NAKAGAWA Yasuhito 中川靖一

Researcher Number	00119603
Other IDs
Affiliation *help	2010 – 2012 : Kitasato University, 薬学部, 教授 2007 – 2008 : 北里大, 薬学部, 教授 2007 – 2008 : Kitasato University, 薬学部, 教授 2002 – 2005 : 北里大, 薬学部, 教授 2002 – 2005 : 北里大学, 薬学部, 教授 … More
Research Field	Principal Investigator 物質生物化学 / Biological pharmacy Except Principal Investigator Biological pharmacy / Biological pharmacy
Keywords	Principal Investigator アラキドン酸 / マクロファージ / Macrophage / リン脂質分子種 / lipid peroxide / Phospholipase / Alkylacylglycerophosphocholine / ホスホリパーゼ / 酸化ストレス / oxidative phospholipid … More Except Principal Investigator グルタチオンペルオキシダーゼ / glutathione peroxidase / ミトコンドリア / カルジオリピン / アラキドン酸 / アポトーシス / apoptosis / mitochondria / 核小体 / 精子形成 / embryo / ゲノム / ガン増殖 / リン脂質 / 凝集 / Transacylase / アルキルエーテル型リン脂質 / 不妊 / 細胞周期 / Arachidonic acid / EPA / 脂質過酸化 / testis / AIF / トランスアシラーゼ / 分化 / 抗酸化酵素 / 胚 / サイクリンD / 白血球 / Alkylether Phospholipid / 糖尿病 / ロイコトリエン / genome / トランスジェニックマウス / シトクロームc / Neutrophil / infertile / 血小板活性化因子 / Diabetes / 胚発生 / C23 / グルタチオンペルオキシザーゼ / 過酸化脂質 / ethane dimethane sulfonate / アルキル型リン脂質 / マクロファージ / cytochrome c / p16 / 精巣 / p53 / cardiolipin / Leukotriene / サイクリン / 線虫 / 生殖細胞 / pRb / RB タンパク質 / 脂質 / CDK / ANT / グルタチオンペルオキソダーゼ / Platelet-activating Factor / 発生 / チトクロームc / グルタチオペルオキシダーゼ / Aggregation / Macrophage / アセチルトランスフェラーゼ / Arachidonic Acid Less

Novel function of cardiolipin in the gonad development ofC. ElegansPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Mechanism of the suppression of cell cycle by the overexpression of nucleolar phospholipids hydroperoxide glutathione peroxidase (PHGPx)Principal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Role of PHGPx on the embryogenesis and sperm maturationPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
The mechanism of protection of apoptosis by the mitochondrial PHGPxPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Mechanism of transcription of phospholipid glutathione peroxidasePrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Metabolism of oxidative phospholipids in peroxidized human erythrocytes membranesPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Changes in the function of neutrophils from diabetic ratsPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Studies on the biosynthetic mechanism of platelet-activating factor and its physiological significance in alveolar macrophages
- Principal Investigator
  
  WAKU Keizo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Faculty of Pharmaceutical Sciences, Teikyo University
Studies on the separation of phospholipase A_2 preferred the arachidonoyl species of phospholipidsPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Faculty of Pharmaceutical Sciences, Teikyo University
The study of the arachidonoyl molecular species of alkylacyl glycerophosphocholine of rabbit alveolar macrophagesPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yasuhito
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Teikyo University

All 2013 2012 2011 2010 2008 2007 2005 2004 Other

All Journal Article Presentation

[Journal Article] Metabolism and biological function of cardiolipin2013
- Author(s)
  Nakagawa Y.Yakugaku Zasshi
- Data Source
  KAKENHI-PROJECT-22590072
[Journal Article] Metabolism and biological function of cardiolipin.2013
- Author(s)
  Yasuhito Nakagawa
- Journal Title
  
  Yakugaku Zasshi
  
  Volume : 133 Pages : 561-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590072
[Journal Article] Deficiency of cardiolipin synthase causes abnormalmitochondrial function and morphology in germ cells of Caenorhabditis elegans2012
- Author(s)
  Sakamoto T., Inoue T., Otomo Y., Yokomori N., Ohno M., Arai H., and Nakagawa Y
- Journal Title
  
  J. Biol. Chem
  
  Volume : 287 Pages : 4590-4601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590072, KAKENHI-PROJECT-23227004
[Journal Article] Recent studies of cardiolipin as a novel modulator of apoptosis2011
- Author(s)
  Nakagawa Y
- Journal Title
  
  Seikagaku
  
  Volume : 83 Pages : 475-484
- Data Source
  KAKENHI-PROJECT-22590072
[Journal Article] アポトーシス制御因子としてのカルジオリピン研究の現状2011
- Author(s)
  中川靖一
- Journal Title
  
  生化学
  
  Volume : 83 Pages : 475-484
- Data Source
  KAKENHI-PROJECT-22590072
[Journal Article] Up-regulation of phospholipid hydroperoxide glutathione peroxidase in rat casein-induced polymorphonuclear neutrophills.2005
- Author(s)
  Hattori H, Imai H, Hanamoto A, Furuhama K, Nakagawa Y
- Journal Title
  
  Biochem.J. 389
  
  Pages : 279-287
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Involvement of hydroperoxidase in mitochondria in the induction of apoptosis by eicosapentaenoic acid.2005
- Author(s)
  Koumura T, Nakamura.C, Nakagawa Y
- Journal Title
  
  Free Rad.Res. 39(3)
  
  Pages : 225-235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Up-regulation of phospholipid hydroperoxide glutathione peroxidase in rat casein-induced polymorphonuclear neutrophiils.2005
- Author(s)
  Hattori H, Imai H, Hanamoto A, Furuhama K, Nakagawa Y
- Journal Title
  
  Biochem. J. 389
  
  Pages : 279-287
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Induction of phospholipid hydroperoxide glutathione peroxidase in human polymorphonuclear neutrophills and HL60 cells stimulated with TNF-α.2005
- Author(s)
  Hattori H, Imai H, Furuhama K, Sato O, Nakagawa Y
- Journal Title
  
  Biochemical and Biophysical Research Communications 337
  
  Pages : 464-473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Involvement of hydroperoxidase in mitochondria in the induction of apoptosis by eicosapentaenoic acid.2005
- Author(s)
  Koumura T, Nakamura C, Nakagawa Y
- Journal Title
  
  Free Rad. Res. 39(3)
  
  Pages : 225-235
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment.2005
- Author(s)
  Koumura T, Nakamura C, Nakagawa Y
- Journal Title
  
  Free Rad. Res. 39(10)
  
  Pages : 1083-1089
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment.2005
- Author(s)
  Koumura T, Nakamura C, Nakagawa Y
- Journal Title
  
  Free Rad.Res. 39(10)
  
  Pages : 1083-1089
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Induction of phospholipid hydroperoxide glutathione peroxidase in human polymorphonuclear neutrophills and HL60 cells stimulated with TNFα.2005
- Author(s)
  Hattori H, Imai H, Furuhama K, Sato O, Nakagawa Y
- Journal Title
  
  Biochemical and Biophysical Research Communications 337
  
  Pages : 464-473
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Inhibition of apoptotic signal by the peroxidation of cardiolipin of mitochondria.2004
- Author(s)
  Nakagawa Y
- Journal Title
  
  Ann. N. Y. Sci 1011
  
  Pages : 177-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Initiation of apoptotic signal by the peroxidation of cardiolipin of mitochondria2004
- Author(s)
  Nakagawa Y
- Journal Title
  
  Ann.N.Y.Acad.Sci 1011
  
  Pages : 177-184
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase as a antiapototic factor2004
- Author(s)
  Nakagawa Y.
- Journal Title
  
  Biol.Pharm.Bull 27(7)
  
  Pages : 956-960
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as a antiapoptotic factor.2004
- Author(s)
  Nakagawa Y
- Journal Title
  
  Biol. Pharm. Bull. 27
  
  Pages : 956-960
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as a antiapoptotic factor.2004
- Author(s)
  Nakagawa Y
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages : 956-960
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Journal Article] Inhibition of apoptotic signal by the peroxidation of cardiolipin of mitochondria.2004
- Author(s)
  Nakagawa Y
- Journal Title
  
  Ann.N.Y.Sci 1011
  
  Pages : 177-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590059
[Presentation] カルジオリピン合成酵素はC. elegansの生殖細胞の増殖に必要である2012
- Author(s)
  坂本太郎、井上貴雄、新井洋由、中川靖一
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] A role for cardiolipin in the gonad development of Caenorhabditis elegans2011
- Author(s)
  Taro Sakamoto, Nagaharu Yokomori, Yukae Otomo, Motoki Ohno, Takao Inoue, Hiroyuki Arai, Yasuhito Nakagawa
- Organizer
  18^<th> International C.elegans Meeting
- Place of Presentation
  カリフォルニア大学ロサンゼルス校
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] カルジオリピン欠損線虫におけるミトコンドリア機能の生化学的解析2011
- Author(s)
  坂本太郎、横森永治、大友由佳永、大野元希、井上貴雄、新井洋由、中川靖一
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都府・国立京都国際会館
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] 線虫の生殖腺形成におけるカルジオリピンの生理的役割2010
- Author(s)
  大野元希、坂本太郎、大友由佳永、横森永治、井上貴雄、新井洋由、中川靖一
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫県・神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] カルジオリピン欠損線虫の生化学的解析2010
- Author(s)
  横森永治、坂本太郎、大友由佳永、大野元希、井上貴雄、新井洋由、中川靖一
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫県・神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] Characterization of phenotypes for the sterility in cardiolipin-deficient mutants2010
- Author(s)
  Motoki Ohno, Taro Sakamoto, Yukae Ohtomo, Nagaharu Yokomori, Takao Inoue, Hiroyuki Arai, Yasuhito Nakagawa
- Organizer
  4^<th> East Asia C.elegans Meeting
- Place of Presentation
  東京都・国立オリンピック記念青少年総合センター
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] 線虫C.elegansの生殖腺形成におけるカルジオリピンの生理機能の解析2010
- Author(s)
  坂本太郎、井上貴雄、大友由佳永、新井洋由、中川靖一
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  群馬県・伊香保森秋旅館
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] Cardiolipin is required for the maintenance of mitochondrial membrane potential of C.elegans gonad.2010
- Author(s)
  Nagaharu Yokomori, Taro Sakamoto, Yukae Ohtomo, Motoki Ohno, Takao Inoue, Hiroyuki Arai.Yasuhito Nakagawa
- Organizer
  4^<th> East Asia C.elegans Meeting
- Place of Presentation
  東京都・国立オリンピック記念青少年総合センター
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-22590072
[Presentation] 核小体型PHGPx細胞増殖抑制の解析2008
- Author(s)
  鈴木, 今井, 大川, 杉本, 喜来, 鈴木, 中川
- Organizer
  日本分子生物学会、日本生化学学会合同会議
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590074
[Presentation] 12007
- Author(s)
  喜来、今井、杉本、鈴木、中川
- Organizer
  第80会日本生化学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19590074
[Presentation] カルジオリピン合成酵素はC. elegansの生殖細胞の増殖に必要である
- Author(s)
  坂本太郎、井上貴雄、新井洋由、中川靖一
- Organizer
  2012年度　第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590072

1. IMAI Hirotaka (50255361)

# of Collaborated Projects : 4results

# of Collaborated Products : 6results
2. SAKAMOTO Taro (10383655)

# of Collaborated Projects : 1results

# of Collaborated Products : 10results
3. OHSHIMA Gennichiro (20050502)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. KOUMURA Tomoko (30337985)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. WAKU Keizo (90013854)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. SUGIURA Takayuki (40130009)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 新井洋由

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 井上貴雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

NAKAGAWA Yasuhito 中川 靖一

Research Projects

Research Products

Co-Researchers

Novel function of cardiolipin in the gonad development ofC. ElegansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of the suppression of cell cycle by the overexpression of nucleolar phospholipids hydroperoxide glutathione peroxidase (PHGPx)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of PHGPx on the embryogenesis and sperm maturationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of protection of apoptosis by the mitochondrial PHGPxPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of transcription of phospholipid glutathione peroxidasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metabolism of oxidative phospholipids in peroxidized human erythrocytes membranesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Changes in the function of neutrophils from diabetic ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the biosynthetic mechanism of platelet-activating factor and its physiological significance in alveolar macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the separation of phospholipase A_2 preferred the arachidonoyl species of phospholipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of the arachidonoyl molecular species of alkylacyl glycerophosphocholine of rabbit alveolar macrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Metabolism and biological function of cardiolipin2013

Author(s)

Data Source

[Journal Article] Metabolism and biological function of cardiolipin.2013

Author(s)

Journal Title

Data Source

[Journal Article] Deficiency of cardiolipin synthase causes abnormalmitochondrial function and morphology in germ cells of Caenorhabditis elegans2012

Author(s)

Journal Title

Data Source

[Journal Article] Recent studies of cardiolipin as a novel modulator of apoptosis2011

Author(s)

Journal Title

Data Source

[Journal Article] アポトーシス制御因子としてのカルジオリピン研究の現状2011

NAKAGAWA Yasuhito 中川靖一