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nakagawa yasuhito  中川 靖一

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NAKAGAWA Yasuhito  中川 靖一

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Researcher Number 00119603
Other IDs
Affiliation (Current) 2025: 北里大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help 2010 – 2012: 北里大学, 薬学部, 教授
2007 – 2008: Kitasato University, 薬学部, 教授
2002 – 2005: 北里大学, 薬学部, 教授
1998 – 2000: 北里大学, 薬学部, 教授
1993 – 1996: 北里大学, 薬学部, 教授
1987 – 1988: 帝京大学, 薬学部, 講師
1986: Faculty of Pharmaceutical Sciences, Teikyo Univ., Lecturer, 薬学部, 講師
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy / 物質生物化学
Except Principal Investigator
Biological pharmacy
Keywords
Principal Investigator
グルタチオンペルオキシダーゼ / glutathione peroxidase / アラキドン酸 / ミトコンドリア / Macrophage / リン脂質分子種 / マクロファージ / apoptosis / アポトーシス / mitochondria … More / 過酸化脂質 / カルジオリピン / 核小体 / Calcium / Phospholipase / Arachidonic Acid / カルモデュリン / カルシュウム / ホスホリパーゼ / Molecular species / Alkylacylglycerophosphocholine / アルキル型コリンリン脂質 / embryo / testis / ethane dimethane sulfonate / 精子形成 / グルタチオペルオキシダーゼ / トランスジェニックマウス / 胚発生 / 胚 / 精巣 / cytochrome c / cardiolipin / ANT / 脂質過酸化 / シトクロームc / AIF / EPA / チトクロームc / genome / infertile / 抗酸化酵素 / ゲノム / 不妊 / ageing / aldehydic phospholipid / oxidative phospholipid / lipid peroxide / oxidative stress / 生体膜 / 生成膜 / 老化 / アルデヒド型リン脂質 / 酸化型リン脂質 / 酸化ストレス / Diabetes / Aggregation / Neutrophil / Leukotriene / Arachidonic acid / リン脂質 / 凝集 / 白血球 / 糖尿病 / ロイコトリエン / 分化 / 発生 / 生殖細胞 / 線虫 / 脂質 / p16 / pRb / CDK / サイクリンD / グルタチオンペルオキソダーゼ / C23 / p53 / ガン増殖 / グルタチオンペルオキシザーゼ / RB タンパク質 / サイクリン / 細胞周期 … More
Except Principal Investigator
Transacylase / Arachidonic Acid / Platelet-activating Factor / Macrophage / Alkylether Phospholipid / アルキル型リン脂質 / アセチルトランスフェラーゼ / トランスアシラーゼ / アラキドン酸 / 血小板活性化因子 / マクロファージ / アルキルエーテル型リン脂質 Less
  • Research Projects

    (10 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (6 People)
  •  Novel function of cardiolipin in the gonad development ofC. ElegansPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Mechanism of the suppression of cell cycle by the overexpression of nucleolar phospholipids hydroperoxide glutathione peroxidase (PHGPx)Principal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Role of PHGPx on the embryogenesis and sperm maturationPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  The mechanism of protection of apoptosis by the mitochondrial PHGPxPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Mechanism of transcription of phospholipid glutathione peroxidasePrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Metabolism of oxidative phospholipids in peroxidized human erythrocytes membranesPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Changes in the function of neutrophils from diabetic ratsPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Studies on the biosynthetic mechanism of platelet-activating factor and its physiological significance in alveolar macrophages

    • Principal Investigator
      WAKU Keizo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Faculty of Pharmaceutical Sciences, Teikyo University
  •  Studies on the separation of phospholipase A_2 preferred the arachidonoyl species of phospholipidsPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Faculty of Pharmaceutical Sciences, Teikyo University
  •  The study of the arachidonoyl molecular species of alkylacyl glycerophosphocholine of rabbit alveolar macrophagesPrincipal Investigator

    • Principal Investigator
      NAKAGAWA Yasuhito
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Teikyo University

All 2013 2012 2011 2010 2008 2007 2005 2004 Other

All Journal Article Presentation Other

  • [Journal Article] Metabolism and biological function of cardiolipin.2013

    • Author(s)
      Yasuhito Nakagawa
    • Journal Title

      Yakugaku Zasshi

      Volume: 133 Pages: 561-574

    • NAID

      130003361950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Journal Article] Metabolism and biological function of cardiolipin2013

    • Author(s)
      Nakagawa Y.Yakugaku Zasshi
    • Volume
      133
    • Pages
      561-574
    • NAID

      130003361950

    • Data Source
      KAKENHI-PROJECT-22590072
  • [Journal Article] アポトーシス制御因子としてのカルジオリピン研究の現状2011

    • Author(s)
      中川靖一
    • Journal Title

      生化学

      Volume: 83 Pages: 475-484

    • NAID

      10029068768

    • Data Source
      KAKENHI-PROJECT-22590072
  • [Journal Article] Recent studies of cardiolipin as a novel modulator of apoptosis2011

    • Author(s)
      Nakagawa Y
    • Journal Title

      Seikagaku

      Volume: 83 Pages: 475-484

    • NAID

      10029068768

    • Data Source
      KAKENHI-PROJECT-22590072
  • [Journal Article] Induction of phospholipid hydroperoxide glutathione peroxidase in human polymorphonuclear neutrophills and HL60 cells stimulated with TNFα.2005

    • Author(s)
      Hattori H, Imai H, Furuhama K, Sato O, Nakagawa Y
    • Journal Title

      Biochemical and Biophysical Research Communications 337

      Pages: 464-473

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Up-regulation of phospholipid hydroperoxide glutathione peroxidase in rat casein-induced polymorphonuclear neutrophiils.2005

    • Author(s)
      Hattori H, Imai H, Hanamoto A, Furuhama K, Nakagawa Y
    • Journal Title

      Biochem. J. 389

      Pages: 279-287

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Involvement of hydroperoxidase in mitochondria in the induction of apoptosis by eicosapentaenoic acid.2005

    • Author(s)
      Koumura T, Nakamura C, Nakagawa Y
    • Journal Title

      Free Rad. Res. 39(3)

      Pages: 225-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Involvement of hydroperoxidase in mitochondria in the induction of apoptosis by eicosapentaenoic acid.2005

    • Author(s)
      Koumura T, Nakamura.C, Nakagawa Y
    • Journal Title

      Free Rad.Res. 39(3)

      Pages: 225-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Up-regulation of phospholipid hydroperoxide glutathione peroxidase in rat casein-induced polymorphonuclear neutrophills.2005

    • Author(s)
      Hattori H, Imai H, Hanamoto A, Furuhama K, Nakagawa Y
    • Journal Title

      Biochem.J. 389

      Pages: 279-287

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment.2005

    • Author(s)
      Koumura T, Nakamura C, Nakagawa Y
    • Journal Title

      Free Rad.Res. 39(10)

      Pages: 1083-1089

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Induction of phospholipid hydroperoxide glutathione peroxidase in human polymorphonuclear neutrophills and HL60 cells stimulated with TNF-α.2005

    • Author(s)
      Hattori H, Imai H, Furuhama K, Sato O, Nakagawa Y
    • Journal Title

      Biochemical and Biophysical Research Communications 337

      Pages: 464-473

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment.2005

    • Author(s)
      Koumura T, Nakamura C, Nakagawa Y
    • Journal Title

      Free Rad. Res. 39(10)

      Pages: 1083-1089

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Inhibition of apoptotic signal by the peroxidation of cardiolipin of mitochondria.2004

    • Author(s)
      Nakagawa Y
    • Journal Title

      Ann. N. Y. Sci 1011

      Pages: 177-184

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase as a antiapototic factor2004

    • Author(s)
      Nakagawa Y.
    • Journal Title

      Biol.Pharm.Bull 27(7)

      Pages: 956-960

    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Initiation of apoptotic signal by the peroxidation of cardiolipin of mitochondria2004

    • Author(s)
      Nakagawa Y
    • Journal Title

      Ann.N.Y.Acad.Sci 1011

      Pages: 177-184

    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as a antiapoptotic factor.2004

    • Author(s)
      Nakagawa Y
    • Journal Title

      Biol.Pharm.Bull. 27

      Pages: 956-960

    • NAID

      110003608894

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Inhibition of apoptotic signal by the peroxidation of cardiolipin of mitochondria.2004

    • Author(s)
      Nakagawa Y
    • Journal Title

      Ann.N.Y.Sci 1011

      Pages: 177-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Journal Article] Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as a antiapoptotic factor.2004

    • Author(s)
      Nakagawa Y
    • Journal Title

      Biol. Pharm. Bull. 27

      Pages: 956-960

    • NAID

      110003608894

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590059
  • [Presentation] カルジオリピン合成酵素はC. elegansの生殖細胞の増殖に必要である2012

    • Author(s)
      坂本太郎、井上貴雄、新井洋由、中川靖一
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] A role for cardiolipin in the gonad development of Caenorhabditis elegans2011

    • Author(s)
      Taro Sakamoto, Nagaharu Yokomori, Yukae Otomo, Motoki Ohno, Takao Inoue, Hiroyuki Arai, Yasuhito Nakagawa
    • Organizer
      18^<th> International C.elegans Meeting
    • Place of Presentation
      カリフォルニア大学ロサンゼルス校
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] カルジオリピン欠損線虫におけるミトコンドリア機能の生化学的解析2011

    • Author(s)
      坂本太郎、横森永治、大友由佳永、大野元希、井上貴雄、新井洋由、中川靖一
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都府・国立京都国際会館
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] 線虫C.elegansの生殖腺形成におけるカルジオリピンの生理機能の解析2010

    • Author(s)
      坂本太郎、井上貴雄、大友由佳永、新井洋由、中川靖一
    • Organizer
      第52回日本脂質生化学会
    • Place of Presentation
      群馬県・伊香保森秋旅館
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] 線虫の生殖腺形成におけるカルジオリピンの生理的役割2010

    • Author(s)
      大野元希、坂本太郎、大友由佳永、横森永治、井上貴雄、新井洋由、中川靖一
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      兵庫県・神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] Characterization of phenotypes for the sterility in cardiolipin-deficient mutants2010

    • Author(s)
      Motoki Ohno, Taro Sakamoto, Yukae Ohtomo, Nagaharu Yokomori, Takao Inoue, Hiroyuki Arai, Yasuhito Nakagawa
    • Organizer
      4^<th> East Asia C.elegans Meeting
    • Place of Presentation
      東京都・国立オリンピック記念青少年総合センター
    • Year and Date
      2010-07-12
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] カルジオリピン欠損線虫の生化学的解析2010

    • Author(s)
      横森永治、坂本太郎、大友由佳永、大野元希、井上貴雄、新井洋由、中川靖一
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      兵庫県・神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] Cardiolipin is required for the maintenance of mitochondrial membrane potential of C.elegans gonad.2010

    • Author(s)
      Nagaharu Yokomori, Taro Sakamoto, Yukae Ohtomo, Motoki Ohno, Takao Inoue, Hiroyuki Arai.Yasuhito Nakagawa
    • Organizer
      4^<th> East Asia C.elegans Meeting
    • Place of Presentation
      東京都・国立オリンピック記念青少年総合センター
    • Year and Date
      2010-07-12
    • Data Source
      KAKENHI-PROJECT-22590072
  • [Presentation] 核小体型PHGPx細胞増殖抑制の解析2008

    • Author(s)
      鈴木, 今井, 大川, 杉本, 喜来, 鈴木, 中川
    • Organizer
      日本分子生物学会、日本生化学学会 合同会議
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-19590074
  • [Presentation] 12007

    • Author(s)
      喜来、今井、杉本、鈴木、中川
    • Organizer
      第80会日本生化学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-19590074
  • [Presentation] カルジオリピン合成酵素はC. elegansの生殖細胞の増殖に必要である

    • Author(s)
      坂本太郎、井上貴雄、新井洋由、中川靖一
    • Organizer
      2012年度 第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590072
  • []

  • 1.  IMAI Hirotaka (50255361)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 2.  SAKAMOTO Taro (10383655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 3.  OHSHIMA Gennichiro (20050502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KOUMURA Tomoko (30337985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  WAKU Keizo (90013854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SUGIURA Takayuki (40130009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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