SUGIYAMA Kimio 杉山公男

Researcher Number	00126781
Other IDs
Affiliation *help	2016 – 2018 : 静岡大学, 農学部, 教授 2005 – 2011 : 静岡大学, 農学部, 教授 2002 – 2003 : Faculty of Agriculture, Professor, 農学部, 教授 2000 : 静岡大学, 農学部, 教授 1996 – 1997 : 静岡大学, 農学部, 教授 1988 – 1989 : 静岡大学, 農学部, 助教授
Review Section/Research Field	Principal Investigator Food science / 食品科学・栄養科学 / 応用生物化学・栄養化学 Except Principal Investigator 食品科学・栄養科学 / Food science / 広領域
Keywords	Principal Investigator タンパク質 / ホモシステイン / 動脈硬化 / アミノ酸 / ラット / 含硫アミノ酸 / 栄養学 / シイタケ / amino acid / protein … More Except Principal Investigator ムチン / bulk-forming effect / NGF / bulk-formingeffect / mushrooms / dietary antigen / 短鎖脂肪酸 / サイトカイン / 機能性物質 / 水中沈定体積 / 抗酸化 / 肝障害抑制 / 大腸炎 / 食物繊維 / 治療 / 抗アレルギー / アミロイドβ / IgA / レクチン / 難消化性デンプン / レジスタントスターチ / short-chain fatty acid / anti-oxidant / mucin / resistant starch / anti-allergy / dietary fiber / amyloid-β / colitis / liver injury / ラット / 食事抗原 / 疾病予防 / キノコ / マトリックスメタロプロテアーゼ / 摂食抑制 / settling volume in water Less

Studies on the regulation of homocysteine metabolism by dietary factorsPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kimio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shizuoka University
Studies on the regulation of plasma homocysteine concentration by protein and amino acidPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kimio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shizuoka University
Research on the mechanism of stimulated mucin secrefion by dietary fiber ingestion and its physiological effects
- Principal Investigator
  
  MORITA Tatsuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shizuoka University
Studies on the regulation of plasma homocysteine concentration by food constituentsPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kimio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shizuoka University
Studies on the regulation, by proteins and amino acids of pathogenisis of hepatitisPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kimio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Shizuoka University
Research for the regulation of large bowel fermentation of resistant starch and its application for the experimental colitis
- Principal Investigator
  
  MORITA Tatsuya
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Shizuoka University
Research on functional substances from mushrooms showing preventing or curing effects on some diseases
- Principal Investigator
  
  KAWAGISHI Hirokazu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Shizuoka University
The relationship between the hypocholesterolemic sction of Shiitake and phospholipid metabolimPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kimio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Shizuoka University
Regulation of plasma cholesterol level by sulfur-containing amino acidsPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kimio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Shizuoka University, Faculty of Agriculture

All 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] アミノ酸の機能特性ーライフサイエンスにおける新しい波ー2007
- Author(s)
  杉山公男(分担執筆)
- Total Pages
  45
- Publisher
  建帛社
- Data Source
  KAKENHI-PROJECT-17580108
[Book] キノコの生理活性と機能(分担執筆)2005
- Author(s)
  杉山公男
- Total Pages
  19
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-17580108
[Journal Article] Effects of betaine supplementation and choline deficiency on folate Deficiency-induced hyperhomocysteinemia in rats2012
- Author(s)
  Y.Liu, Y.Liu, T.Morita, K.Sugiyama
- Journal Title
  
  J.Nutr.Sci.Vitaminol.
  
  Volume : 58 Pages : 69-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats2012
- Author(s)
  Y.Liu, Y.Liu, T.Morita, M.Mori, K.Sugiyama
- Journal Title
  
  J.Nutr.Sci.Vitaminol.
  
  Volume : 58 Pages : 78-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Effect of dietary supplementation with folate on choline deficiency-induced hyperhomocysteinemia in rats2012
- Author(s)
  Y.Liu, Y.Liu, T.Morita, M.Mori, K.Sugiyama
- Journal Title
  
  J.Nutr.Sci.Vitaminol.
  
  Volume : 58 Pages : 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyper homocyste inemia in rats2012
- Author(s)
  Liu Y, Liu Y, Morita T, Mori M, and Sugiyama K
- Journal Title
  
  J. Nutr. Sci. Vitaminol.
  
  Volume : 58 Pages : 78-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Effect of dietary supplementation with folate on choline deficiency-induced hyper homocysteinemia inrats2012
- Author(s)
  Liu Y, Liu Y, Morita T, Mori M, and Sugiyama K
- Journal Title
  
  J. Nutr Sci. Vitaminol.
  
  Volume : 58 Pages : 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Effects of betaine supplementation andcholine deficiency on folate deficiency-induced hyper homocysteinemia in rats2012
- Author(s)
  Liu Y, Liu Y, Morita T, and Sugiyama K
- Journal Title
  
  J. Nutr. Sci. Vitaminol.
  
  Volume : 58 Pages : 69-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Methionine and serine synergistically suppress hyperhomocysteinemia induced by choline deficiency, but not by guanidinoacetic acid, in rats fed a low casein diet2011
- Author(s)
  Y.Liu, Y.Liu, T.Morita, K.Sugiyama
- Journal Title
  
  Biosci.Biotechnol.Biochem.
  
  Volume : 75 Pages : 2333-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Motioning and serine synergistically suppress hyper homocysteinemia induced by choline deficiency, but not by guanidino aceticacid, in rats fed a low casein diet2011
- Author(s)
  Liu Y, Liu Y, Morita T, and Sugiyama K
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume : 75 Pages : 2333-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] High casein diet decreases plasma homocysteine concentration in rats2009
- Author(s)
  K.Ohuichi, Y.Matsumoto, T.Morita, K.Sugiyama
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 55
  
  Pages : 22-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580137
[Journal Article] Hypohomocysteinemic effect of cysteine is associated with increased plasma cysteine concentration in rats fed diets low in protein and methionine levels2009
- Author(s)
  Kawakami Y, Ohuchi S, Morita T, and Sugiyama K.
- Journal Title
  
  J. Nutr. Sci. Vitaminol. 55
  
  Pages : 66-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] Hepatic cystathionine β-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet : associationwith plasma homocysteine concetrations2009
- Author(s)
  Ohuchi S, Morita T, Mori M, and Sugiyama K.
- Journal Title
  
  J. Nutr. Sci. Vitaminol. 55
  
  Pages : 178-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] High casein diet decreases plasma homocysteine concentration in rats2009
- Author(s)
  Ohuchi S, Matsumoto Y, Morita T, and Sugiyama K.
- Journal Title
  
  J. Nutr. Sci. Vitaminol. 55
  
  Pages : 22-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] Hyperhomocysteinemia induced by guanidinoacetic acid is effectively suppressed by choline and betaine in rats2008
- Author(s)
  Setoue M, Ohuchi S, Morita T, and Sugiyama K.
- Journal Title
  
  Biosci. Biotechnol. Biochem 72
  
  Pages : 1696-1703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] Effect of dietary soybean protein level on the plasma homocysteine concentration in rats2008
- Author(s)
  Okawa H, Morita T, and Sugiyama K.
- Journal Title
  
  Biosci. Biotechnol. Biochem 72
  
  Pages : 1607-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] High-casein diet suppresses guanidinoacetic acid-induced hyperhomocysteinemia and potentiates the hypohomocysteinemic effect of serine in rats2008
- Author(s)
  Ohuchi S, Matsumoto Y, Morita T, and Sugiyama K.
- Journal Title
  
  Biosci. Biotechnol. Biochem 72
  
  Pages : 3258-3264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] Effects of various amino acids on methionine-induced hyperhomocysteinemia in rats2008
- Author(s)
  Fukada S, Morita T, and Sugiyama K.
- Journal Title
  
  Biosci. Biotechnol. Biochem 72
  
  Pages : 1940-1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] Choline deprivation induces hyperhomocysteinemia in rats fed low methionine diets2008
- Author(s)
  Setoue M, Ohuchi S, Morita T, and Sugiyama K.
- Journal Title
  
  J. Nutr. Sci. Vitaminol 54
  
  Pages : 483-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580135
[Journal Article] ラットの血漿ホモシステイン濃度に及ぼす食餌タンパク質レベルの影響2006
- Author(s)
  杉山公男他
- Journal Title
  
  必須アミノ酸研究 No.176
  
  Pages : 48-56
- Data Source
  KAKENHI-PROJECT-17580108
[Presentation] コリン欠乏による高ホモシステイン血章に及ぼす葉酸の効果2011
- Author(s)
  劉穎, 劉軼群, ドヴァンタイ, 杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  お茶の水女子大学(東京都)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] 低メチオニン食へのシステイン添加による脂肪肝の生成について2011
- Author(s)
  土屋諒, 劉軼群, 石神有介, 杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  お茶の水女子大学(東京都)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] BHMT活性に影響を及ぼす食餌因子とホモシステイン代謝2011
- Author(s)
  劉軼群, 劉穎, 土屋諒, 杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  お茶の水女子大学(東京都)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] 高タンパク質食が血漿ホモシステイン濃度を上昇させない機構について2010
- Author(s)
  呉育如、鈴木朋恵、大久保昭宏、杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  アスティー徳島(徳島市)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] 葉酸欠乏による高ホモシステイン血症に及ぼすベタインおよびコリンの効果2010
- Author(s)
  劉穎、劉戟群、杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  アスティー徳島(徳島市)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] 血漿ホモシステイン濃度に及ぼすコリン欠乏の影響と食餌タンパク質レベルとの関係2010
- Author(s)
  劉軟群、劉穎、杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  アスティー徳島(徳島市)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] タンパク質およびアミノ酸摂取量とラット肝臓CBS活性との関係2009
- Author(s)
  杉山公男
- Organizer
  第63回日本栄養・食糧学会大会
- Place of Presentation
  長崎ブリックホール(長崎市)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19580135
[Presentation] 血漿ホモシステイン濃度に及ぼす食餌タンパク質の種類と量の影響2009
- Author(s)
  呉育如, 姚暁萍, 大内誠也, 杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] べたイン欠乏を伴う高ホモシステイン血症に及ぼす食餌へのメチオニンとセリン添加の影響2009
- Author(s)
  劉軟群, 大内誠也, 杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] タンパク質およびアミノ酸摂取量とラット肝臓CBS活性との関係2009
- Author(s)
  大内誠也, 森誠, 高坂哲也, 杉山公男
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] 食事因子による含硫アミノ酸代謝の制御に関する研究2009
- Author(s)
  杉山公男
- Organizer
  日本栄養・食糧
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21580137
[Presentation] タンパク質およびアミノ酸摂取量とラット肝臓CBS 活性との関係2009
- Author(s)
  杉山公男, 他
- Organizer
  第63回日本栄養・食糧学会大会
- Place of Presentation
  長崎新聞文化ホール
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19580135
[Presentation] D-システイン投与は血漿ホモシステイン濃度を効果的に低下させる2008
- Author(s)
  杉山公男, 他
- Organizer
  第62回日本栄養・食糧学会大会
- Place of Presentation
  女子栄養大学坂戸キャンパス
- Year and Date
  2008-05-04
- Data Source
  KAKENHI-PROJECT-19580135
[Presentation] D-システイン投与はラットの血漿ホモシステイン濃度を効果的に低下させる2008
- Author(s)
  杉山公男
- Organizer
  第62回日本栄養・食糧学会大会
- Place of Presentation
  女子栄養大学坂戸キャンパス
- Year and Date
  2008-05-04
- Data Source
  KAKENHI-PROJECT-19580135

1. MORITA Tatsuya (90332692)

# of Collaborated Projects : 5results

# of Collaborated Products : 8results
2. KAWAGISHI Hirokazu (70183283)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. MURATA Takeomi (30273171)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. TOKUYAMA Shinji (60283347)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. MATSUDA Tsukasa (20144131)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

SUGIYAMA Kimio 杉山 公男

Research Projects

Research Products

Co-Researchers

Studies on the regulation of homocysteine metabolism by dietary factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulation of plasma homocysteine concentration by protein and amino acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the mechanism of stimulated mucin secrefion by dietary fiber ingestion and its physiological effects

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulation of plasma homocysteine concentration by food constituentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulation, by proteins and amino acids of pathogenisis of hepatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for the regulation of large bowel fermentation of resistant starch and its application for the experimental colitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on functional substances from mushrooms showing preventing or curing effects on some diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between the hypocholesterolemic sction of Shiitake and phospholipid metabolimPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of plasma cholesterol level by sulfur-containing amino acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] アミノ酸の機能特性ーライフサイエンスにおける新しい波ー2007

Author(s)

Total Pages

Publisher

Data Source

[Book] キノコの生理活性と機能(分担執筆)2005

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Effects of betaine supplementation and choline deficiency on folate Deficiency-induced hyperhomocysteinemia in rats2012

Author(s)

Journal Title

Data Source

[Journal Article] Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats2012

Author(s)

Journal Title

Data Source

[Journal Article] Effect of dietary supplementation with folate on choline deficiency-induced hyperhomocysteinemia in rats2012

Author(s)

Journal Title

Data Source

SUGIYAMA Kimio 杉山公男