Takeyama Naoshi 武山直志

… Alternative Names

TAKEYAMA Naoshi 武山直志

武山直志タケヤマナオシ

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Researcher Number	00155053
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 愛知医科大学, 名誉教授
Affiliation (based on the past Project Information) *help	2023: 愛知医科大学, 愛知医科大学, 名誉教授 2021 – 2022: 愛知医科大学, 医学部, 特命教授 2021: 愛知医科大学, 医学部, 名誉教授 2015 – 2020: 愛知医科大学, 医学部, 教授 2017: 愛知医科大学, 医学部, 准教授 … More 2011 – 2014: 藤田保健衛生大学, 医学部, 教授 2013: 藤田保健衛生大学, 医学部救命救急医学講座, 教授 2010: 藤田保健衛生大学, 医学部, 准教授 2007 – 2009: Aichi Medical University, 医学部, 准教授 2006: 愛知医科大学, 医学部, 助教授 2004: 関西医大, 医学部, 助教授 1998 – 1999: 関西医科大学, 医学部, 講師 1993 – 1995: 関西医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related / General surgery Except Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related / Digestive surgery
Keywords	Principal Investigator lipopolysaccharide / xanthine oxidase / aminotriazole / ARDS / tungsten / DAMPs / angiopoietin 1 / 血管内皮前駆細胞 / 免疫担当遺伝子 / genomic storm … More / 多発外傷 / マイクロアレイ解析 / 自然免疫 / 重症外傷 / 遺伝子発現 / histone / cell-free DNA / cadherin / F actin / 好中球 / 内皮細胞 / Fアクチン / カドヘリン / 急性呼吸促迫症候群 / NETs / neuregulin / angiopoetin / tight junction / 血管透過性亢進 / 血管内皮細胞 / 敗血症性ショック / MPO-DNA / Hydrogen peroxide / xanthine dehydrogenase / グルタチオンモノエステル / PAF / NOS inhibitor / BALF / NO / L-NAME / cf-DNA / CXCL8 / multiplex PCR / PD-１ / 遺伝子解析 / T細胞 / 敗血症 / FACS / syto16 / CD34 / CD31 / CD133 / VEGF / 自家移植 / 内皮前駆細胞 / 急性肺障害 / ALI/ARDS / 集中治療 / 80 / F4 / 脾臓細胞 / 易感染性 / CpG / HLA-DR / 免疫不全 / マクロファージ / マウス / 重症熱傷 / CpG DNA / immunoparalysis / サイトカイン / MHC class II / CpG oligonucleotides / 熱傷 … More Except Principal Investigator 敗血症 / 間葉系幹細胞 / 炎症制御 / 急性呼吸促迫症候群 / cf-DNA / MPO-DNA / ARDS / 自然免疫 / Immunoparalysis / 免疫抑制 / Innate Lymphoid Cell / 骨格筋前駆細胞 / マイクロRNA / 衛星細胞 / 人工呼吸器 / 骨格筋 / 呼吸筋疲労 / 好中球 / 活性酸素種 / 貪食能 / NETｓ / apoptosis / mitochondria / Cytochrome c / zVAD-fmk / TNF-α / L929 / microinjector / チトクローム C / bcl-2 / ミトコンドリア / チロクロームC / アポトーシス / 再生医療 / 神経幹細胞 / 脳虚血 / ES細胞 / 神経再生 / 脳血管障害 / 骨髄幹細胞移植 / immunoparalysis / 骨髄幹細胞 / T細胞 / 骨髄移植 / 免疫不全 / thymosin 4 / cell-free DNA / 免疫染色 / NETs / CXCL8 / VEGF / 骨随前駆細胞 / 呼気 / 単球 / マクロファージ / 急性肺障害 / ヘムオキシゲナーゼI / 酸化ストレス / 一酸化炭素 / ヘムオキシゲナーゼ Less

急性呼吸促迫症候群に対する造血幹細胞移植：炎症制御と血管再生の試み
- Principal Investigator
  
  加納秀記
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Aichi Medical University
Evaluation of gene expression profile during multiple trauma: application of T-iPSPrincipal Investigator
- Principal Investigator
  
  Takeyama Naoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Aichi Medical University
Functional Analysis of Innate Lymphoid Cell in sepsis.
- Principal Investigator
  
  Tsuda Masanobu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Aichi Medical University
The protective effect of mesenchymal stem cells on ICU-acquired muscle weakness
- Principal Investigator
  
  Kano Hideki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Aichi Medical University
Stem cell transplantation for vascular permeability and angiogenesis under surgical stressPrincipal Investigator
- Principal Investigator
  
  Takeyama Naoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Aichi Medical University
Immunoparalysis and analysis of hematopoietic stem cell in sepsis:a trial of regenerative immunoactivity by bone-marrow transplantation
- Principal Investigator
  
  Hattori Tomonori
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Nagoya City University
  Fujita Health University
ES derived neuronal stem cells ameliorate ischemic brain injury in mice
- Principal Investigator
  
  Hata Ryuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Fujita Health University
Effect of mesenchymal stem cells on septic acute renal failurePrincipal Investigator
- Principal Investigator
  
  TAKEYAMA Naoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Fujita Health University
Bone marrow stromal cells and thymosin beta 4 attenuate septic organ failure
- Principal Investigator
  
  KANO Hideki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Fujita Health University
急性肺障害における血管内皮前駆細胞の動態解析:自家移植による再生治療の試みPrincipal Investigator
- Principal Investigator
  
  TAKEYAMA Naoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Fujita Health University
  Aichi Medical University
CpG oligonucleotides activate the immune response in burned micePrincipal Investigator
- Principal Investigator
  
  TAKEYAMA Naoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Aichi Medical University
ヘムオキシゲナーゼ1による生体保護作用:バイオマーカーとしての呼気一酸化炭素
- Principal Investigator
  
  野口宏
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Aichi Medical University
熱傷ストレス下における免疫異常と樹状細胞機能:CpGモチーフによる免疫調整Principal Investigator
- Principal Investigator
  
  武山直志
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Kansai Medical University
Bcl-2 blocks apoptosis by preventing loss of mitochondrial outer membrane integrity
- Principal Investigator
  
  KITAZAWA Yasuhide
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KANSAI MEDICAL UNIVERSITY
Role of reactive oxygen intermediates in lipopolysaccharidemediated hepatic injury in the ratPrincipal Investigator
- Principal Investigator
  
  TAKEYAMA Naoshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University

[Journal Article] Role of Neutrophil Extracellular Traps in Health and Disease Pathophysiology: Recent Insights and Advances2023
- Author(s)
  Md. Monirul Islam, Naoshi Takeyama
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 24 Issue: 21 Pages: 15805-15805
- DOI
  10.3390/ijms242115805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09131
[Journal Article] Quantifying Myeloperoxidase-DNA and Neutrophil Elastase- DNA Complexes from Neutrophil Extracellular Traps by Using a Modified Sandwich ELISA2023
- Author(s)
  Islam, M.M.; Salma, U.; Irahara, T.; Watanabe, E.; Takeyama, N.
- Journal Title
  
  J. Vis. Exp
  
  Volume: 195 Issue: 195 Pages: 64644-64644
- DOI
  10.3791/64644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09131
[Journal Article] Neutrophil extracellular traps are associated with altered human pulmonary artery endothelial barrier function.2021
- Author(s)
  Hisatake Mori, Muhammad Aminul Huq, Md. Monirul Islam, Naoshi Takeyama
- Journal Title
  
  European Journal of Inflammation
  
  Volume: 19 Pages: 1-10
- DOI
  10.1177/20587392211062386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08927
[Journal Article] Complementary Role of Hypothermia Identification to the Quick Sequential Organ Failure Assessment Score in Predicting Patients With Sepsis at High Risk of Mortality: A Retrospective Analysis From a Multicenter, Observational Study.2018
- Author(s)
  Kushimoto S, Gando S, Ogura H, Umemura Y, Saitoh D, Mayumi T, Fujishima S, Abe T, Shiraishi A, Ikeda H, Kotani J, Miki Y, Shiraishi SI, Suzuki K, Suzuki Y, Takeyama N, Takuma K, Tsuruta R, Yamaguchi Y, Yamashita N, Aikawa N.
- Journal Title
  
  J Intensive Care Med
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] Assessment of mortality by qSOFA in patients with sepsis outside ICU: A post hoc subgroup analysis by the Japanese Association for Acute Medicine Sepsis Registry Study Group.2017
- Author(s)
  Umemura Y, Ogura H, Gando S, Kushimoto S, Saitoh D, Mayumi T, Fujishima S, Abe T, Ikeda H, Kotani J, Miki Y, Shiraishi SI, Shiraishi A, Suzuki K, Suzuki Y, Takeyama N, Takuma K, Tsuruta R, Yamaguchi Y, Yamashita N, Aikawa N
- Journal Title
  
  J Infect Chemother
  
  Volume: 23(11) Pages: 757-762
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] Early evaluation of severity in patients with severe sepsis: a comparison with "septic shock" - subgroup analysis of the Japanese Association for Acute Medicine Sepsis Registry (JAAM-SR).2017
- Author(s)
  Tarui T, Yamaguchi Y, Suzuki K, Tsuruta R, Ikeda H, Ogura H, Kushimoto S, Kotani J, Shiraishi SI, Suzuki Y, Takuma K, Takeyama N, Fujishima S, Mayumi T, Miki Y, Yamashita N, Aikawa N, Gando S.
- Journal Title
  
  Acute Med Surg
  
  Volume: 4(4) Pages: 426-431
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] 致死量を超えて内服した市販薬トラベルミン(ジフェンヒドラミン、ジプロフィリン配合剤)の急性中毒例2017
- Author(s)
  竹中信義, 平川昭彦, 加納秀記, 津田雅庸, 武山直志, 服部友紀
- Journal Title
  
  日本臨床救急医学会雑誌
  
  Volume: 20(5) Pages: 672-677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] Increased PD-1 Expression and Altered T Cell Repertoire Diversity Predict Mortality in Patients with Septic Shock: A Preliminary Study.2017
- Author(s)
  Tomino A, Tsuda M, Aoki R, Kajita Y, Hashiba M, Terajima T, Kano H, Takeyama N
- Journal Title
  
  PLoS One
  
  Volume: 12(1)
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] Sandwich ELISA for circulating myeloperoxidase- and neutrophil elastase-DNA complexes released from neutrophil extracellular traps.2016
- Author(s)
  H Kano, M Aminul Huq, M Tsuda, H Noguchi, and N Takeyama
- Journal Title
  
  Advanced Techniques in Biology & Medicine
  
  Volume: 5 Pages: 1-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Journal Article] Clostridium Perfringens Infection in a Febrile Patient with Severe Hemolytic Anemia.2016
- Author(s)
  Hashiba M, Tomino A, Takenaka N, Hattori T, Kano H, Tsuda M, Takeyama N
- Journal Title
  
  Am J Case Rep
  
  Volume: 17 Pages: 219-223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] Neutrophil extracellular traps in patients with sepsis.2015
- Author(s)
  Hashiba M, Huq A, Tomino A, Hirakawa A, Hattori T, Miyabe H, Tsuda M, Takeyama N.
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 194 Issue: 1 Pages: 248-254
- DOI
  10.1016/j.jss.2014.09.033
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] 敗血症性ショック患者におけるT細胞機能障害2015
- Author(s)
  武山直志、富野敦稔、波柴尉充、安藤雅規、後長孝佳、宮部浩道、津田雅庸、服部友紀、加納秀記、平川昭彦
- Journal Title
  
  Shock: 日本Shock学会雑誌
  
  Volume: 29(2) Pages: 9-12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] 多彩な症状を呈した合成カチノン系化合物を含有する危険ドラッグの急性中毒症例2015
- Author(s)
  後長孝佳、服部友紀、安藤雅規、波柴尉充、富野敦稔、宮部浩道、加納秀記、津田雅庸、平川昭彦、武山直志
- Journal Title
  
  日本臨床救急医学会雑誌
  
  Volume: 18(3) Pages: 546-550
- NAID
  130005085622
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] Neutrophil extracellular traps in patients with sepsis.2015
- Author(s)
  Hashiba M, Huq MA, Tomino A, Hirakawa A, Hattori T, Miyabe H, Tsuda M, and Takeyama N
- Journal Title
  
  J Surg Res
  
  Volume: 194 Pages: 248-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592756
[Journal Article] 肺切除術後、健側肺に急性肺障害を認めた1例2015
- Author(s)
  安藤雅規、津田雅庸、後長孝佳、栃井大輔、波柴尉充、富野敦稔、宮部浩道、須田隆、植西憲達、服部友紀、平川昭彦、武山直志
- Journal Title
  
  Japanese Journal of Acute Care Surgery
  
  Volume: 5(1) Pages: 55-58
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462771
[Journal Article] 敗血症性ショック患者におけるT細胞機能障害2014
- Author(s)
  武山直志、富野敦稔、波柴尉充、安藤雅規、後長孝佳、宮部浩道、津田雅庸、服部友紀、加納秀記、平川昭彦
- Journal Title
  
  日本ショック学会誌
  
  Volume: 29 Pages: 9-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592756
[Journal Article] Successful treatment of septic shock due to New Delhi metallo-beta-lactamase-1-producing Klebsiella pneumoniae in a patient transferred from India to Japan.2014
- Author(s)
  Kano H, Hirakawa A, Miyabe H, Hattori T, Mikamo H, Yoshida S, and Takeyama N
- Journal Title
  
  Acute Medicine & Surgery
  
  Volume: 1 Pages: 181-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592756
[Journal Article] A multicenter, prospective validation study of the Japanese Association for Acute Medicine disseminated intravascular coagulation scoring system in patients with severe sepsis2013
- Author(s)
  Gando S、Saitoh D、Ogura H、Fujishima S、Takeyama N 14
- Journal Title
  
  Crit Care
  
  Volume: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592688
[Journal Article] Downregulation of neutrophil derived cell-free DNA in sepsis2013
- Author(s)
  Tomino A、Huq MA、Nakagawa T、Takeyama N
- Journal Title
  
  J Clin Lab Invest Updates
  
  Volume: 1 Pages: 3-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592688
[Journal Article] 4G/5G polymorphism of the plasminogen activator-1 gene is associated with multiple organ dysfunction in critically ill patients2012
- Author(s)
  Huq MA, Takeyama N, Harada M, Miki Y, Takeuchi A, Inoue S, Nakagawa T, Kanou H, Hirakawa A, Noguchi H
- Journal Title
  
  Acta Haematologica
  
  Volume: 127 Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592318
[Journal Article] 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene is associated with multiple organ dysfunction in critically ill patients2012
- Author(s)
  Huq MA, Takeyama N, Harada M, Miki Y
- Journal Title
  
  Acta Haematologica
  
  Volume: 127 Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592318
[Journal Article] CpG oligonucleotides activate the immune response in burned mice2009
- Author(s)
  Yabuki T, Takeyama N, Tsuda M
- Journal Title
  
  J Surg Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591990
[Journal Article] 救急医療領域における感染症2007
- Author(s)
  武山直志
- Journal Title
  
  救急医学 31
  
  Pages: 1132-1137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591990
[Journal Article] 免疫系とサイトカイン2007
- Author(s)
  田中孝也, 矢吹輝, 武山直志
- Journal Title
  
  救急医学 31
  
  Pages: 768-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591990
[Journal Article] 救急領域における感染症とimmunoparalysis2006
- Author(s)
  田中孝也, 武山直志, 升田好樹, 新田正和, 原口義座
- Journal Title
  
  日本救命医療学会誌 20
  
  Pages: 49-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591990
[Journal Article] 免疫調節を行うために必要な免疫学的モニタリング2006
- Author(s)
  武山直志, 田中孝也, 野口宏
- Journal Title
  
  日救急医会誌 17
  
  Pages: 199-209
- NAID
  10018810989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591990
[Presentation] Polymyxin B-immobilized membrane can scavenge damage associated molecular patterns and neutrophil extracellular traps in vitro2023
- Author(s)
  MM. Islam; U. Salma; A. Okumura; E. Watanabe; N. Takeyama
- Organizer
  European Society Intensive Care Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09131
[Presentation] Influence of Neutrophil Extracellular Traps on Vascular Permability2021
- Author(s)
  Mori H, Huq MA, Kajita Y, Islam MM, Takenak N, Gocho T, Maruchi Y, Tsuda M, Takeyama N
- Organizer
  41st Annual conference on Shock
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08927
[Presentation] Low dose acute inorganic arsenic exposure suppresses human neutrophil function in vitro2020
- Author(s)
  Md. Monirul Islama, Naoshi Takeyama
- Organizer
  33rd ESICM LIVES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11598
[Presentation] Removal of circulating NETs-related components with an immobilized polymyxin B filter2019
- Author(s)
  Takeyama N, Gocho T, Maruchi Y, Takenaka N, Mori H, Islam Md M, Huq MA
- Organizer
  39th International symposium on Intensive Care and Emergency medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11598
[Presentation] 血中myeloperoxidase-conjugated DNA測定による敗血症性ショック予後予測の検討2018
- Author(s)
  丸地祐樹、後長孝佳、竹中信義、森久剛、Huq MA、津田雅庸、武山直志
- Organizer
  第33回日本shock学会総会
- Data Source
  KAKENHI-PROJECT-17K11598
[Presentation] Polymyxin-B cartridge can adsorb the NETs related components from plasma2018
- Author(s)
  Muhammad Aminul Huq, Yuka Kajita, Mohammad Monirul Islam, Hisatake Mori, Nobuyoshi Takenaka, Takayoshi Gocho, Yuuki Maruchi, Masanobu Tsuda, Naoshi Takeyama
- Organizer
  41st Annual Conference on Shock
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] Influence of Neutrophil Extracellular Traps on Vascular Permability.2018
- Author(s)
  Mori H, Huq MA, Kajita Y, Islam MM, Takenaka N, Gocho T, Maruchi Y, Tsuda M, Takeyama N.
- Organizer
  41st Annual conference on Shock
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08927
[Presentation] Plasma myeloperoxidase conjugated-DNA level as predictors of outcome and organ dysfunction in septic shock patients: possible therapeutic effect of hemoperfusion with a polymyxin B immobilized fiber column2018
- Author(s)
  Nanshi Takeyama
- Organizer
  38th International Symposium on Intensive Care and Emergency Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462771
[Presentation] Altered T cell Repertoire Diversity and Increased PD-1 Expression Predict Mortality in Patients with Septic Shock.2017
- Author(s)
  N Takeyama; M Tsuda; H Kano; R Aoki; Y Kajita; M Hashiba; T Terashima; A Tomino.
- Organizer
  37th International symposium on Intensive Care and Emergency medicine
- Place of Presentation
  Brussels
- Year and Date
  2017-03-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] Neutrophil extracellular traps (NETs) が血管透過性亢進に及ぼす影響：in vitroの検討2017
- Author(s)
  森久剛、Huq MA, Islam MM, 後長孝佳、丸地祐樹、竹中信義, 津田雅庸,　武山直志
- Organizer
  第３２回日本shock学会総会
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] Neutrophil extracellular traps induce organ damage during sepsis: protective effect of hemoperfusion with a polymyxin B cartridge.2016
- Author(s)
  Muhammad Aminul Huq, Yuka Kajita, Yuki Maruchi, Kato, Atsutoshi Tomino, Ruri Aoki, Hisatake Mori, Masamitsu Hashiba, Tsuguaki Terajima, Masanobu Tsuda, Kano Hideki, and Naoshi Takeyama.
- Organizer
  8th International Shock Congress
- Place of Presentation
  Tokyo
- Year and Date
  2016-10-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] Plasma circulating mayeloperoxidase- and neutrophil-DNA assay is valid biomarker of sepsis2015
- Author(s)
  Huq MA, Tomino A, Hashiba M, Takenaka N, Tsuda M, Takeyama N
- Organizer
  2nd International Conference on Critical Care Medicine
- Place of Presentation
  Bangladesh
- Year and Date
  2015-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] Plasma myeloperoxidase- and neutrophil elastase-DNA assay for measuremet of neutrophil extracellular traps2015
- Author(s)
  MA Huq, Tomino A, Hashiba M, Ando M, Gocho T, Miyabe H, Kano H, Tsuda M, Hattori T, Hirakawa A, Takeyama N
- Organizer
  38th Annual conference on Shock
- Place of Presentation
  Denver, USA
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] INCREASED PD-1 EXPRESSION AND ALTERED T CELL REPERTOIRE DIVERSITY IN SEPTIC SHOCK PATIENTS.2015
- Author(s)
  Takeyama N, Tomino A, Hashiba M, Ando M, Gocho T, Miyabe H, Kano H, Tsuda M, Hattori T, Hirakawa A
- Organizer
  38th Annual conference on Shock
- Place of Presentation
  Denver, USA
- Year and Date
  2015-06-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10997
[Presentation] 敗血症性ショック患者におけるT細胞機能障害2014
- Author(s)
  武山直志、富野敦稔、波柴尉充、安藤雅規、5
- Organizer
  第29回日本ショック学会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 藤田保健衛生大学病院救命ICUにおける敗血症の治療方針2014
- Author(s)
  服部友紀、武山直志、他
- Organizer
  第29回日本救命医療学会総会・学術集会
- Place of Presentation
  東京都八王子市　京王プラザ八王子
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-26462771
[Presentation] Altered T cell repertoire diversity in septic shock patients2014
- Author(s)
  Takeyama N, Tomino A, Hashiba M, Hirakawa A, Hattori T, Miyabe H
- Organizer
  31st International symposium on Intensive Care and Emergency medicine
- Place of Presentation
  Brussels
- Data Source
  KAKENHI-PROJECT-24592756
[Presentation] Altered T cell repertoire diversity in septic shock patients2014
- Author(s)
  Takeyama N、Tomino A、Hashiba M、3
- Organizer
  31^<st> International symposium on Intensive Care and Emergency medicine 2014
- Place of Presentation
  Brussels
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 日本における敗血症(セプシス)の疫学:海外との比較2013
- Author(s)
  小倉裕司、丸藤哲、斎藤大蔵、武山直志15
- Organizer
  第26回日本外科感染症学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] Neutrophil extracellular trap formation capacity is altered in neutrophil from septic patients2013
- Author(s)
  Huq MA, Hirakawa A, Hattori T, Kano H, Miyabe H, Tomino A, Gocho T, Ando M, Nakagawa T, and Takeyama N
- Organizer
  The 7th Asian conference on emergency medicine
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] Neutrophil extracellular trap formation capacity is altered in neutrophil from septic patients2013
- Author(s)
  Huq MA、Takeyama N、8
- Organizer
  The 7^<th> Asian conference on emergency medicine
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] Sepsis alters the extracellular bacterial killing capacity of neutrophil2013
- Author(s)
  Huq MA, Hirakawa A, Hattori T, Takeyama N, Kano H, 6
- Organizer
  Seventh Mediterranean Emergency Medicine Congress
- Place of Presentation
  Marseille
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 重症敗血症の集中治療:日本救急医学会sepsis registry解析結果からの展望2013
- Author(s)
  丸藤哲、斎藤大蔵、藤島清太郎、真弓俊彦、武山直志、14
- Organizer
  第40回日本集中治療医学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 敗血症治療と病態の最前線2013
- Author(s)
  武山直志
- Organizer
  第7回北海道DIC学術講演会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 敗血症治療と病態のupdate2013
- Author(s)
  武山直志
- Organizer
  第28回日本救命医療学会総会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] Epidemiology of severe sepsis in Japanese intensive care units : A prospective multicenter study2013
- Author(s)
  Ogura H、Gando S、Saito D、Fujishima S、Takeyama N, 14
- Organizer
  The 7^<th> Asian conference on emergency medicine
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] Quality of care and mortality of severe sepsis and septic shock in Japan2012
- Author(s)
  Fujishima S、Gando S、Saito D、Takeyama N、14
- Organizer
  ATS 2012 International Conference
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 4G/5G polymorphism of the PAI-1 gene is associated with multiple organ dysfunction in ICU patients2012
- Author(s)
  Huq MA, Takeyama N, Hirakawa A, et al
- Organizer
  The 12th joint scientific congress of KSCCM and JSICM
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-21592318
[Presentation] 外科的感染症とその制御法2012
- Author(s)
  武山直志
- Organizer
  第86回日本感染症学会総会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 敗血症性ショックに対するPMX施行開始時期と治療効果に関する他施設共同前向き研究2012
- Author(s)
  武山直志
- Organizer
  第13回エンドトキシン血症救命治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 4G/5G polymorphism of the PAI-1 gene is associated with multiple organ dysfunction in ICU patients2012
- Author(s)
  Huq A, Takeyama N, Hirakawa A
- Organizer
  The 12^<th> Joint Scientific Congress of JAICM and KSCCM
- Place of Presentation
  千葉
- Year and Date
  2012-02-29
- Data Source
  KAKENHI-PROJECT-21592318
[Presentation] 敗血症病態とその治療;急性血液浄化療法を中心に2011
- Author(s)
  武山直志
- Organizer
  第4回岐阜外傷カンファレンス
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 敗血症:侵襲反応の破綻をいかに回復させるか2011
- Author(s)
  武山直志
- Organizer
  第19回日本集中治療医学会東海北陸地方会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 敗血症2011
- Author(s)
  武山直志
- Organizer
  第1回東海感染症研究会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23592688
[Presentation] 高度侵襲下におけるimmunoparalysisの病態と治療戦略2007
- Author(s)
  武山直志
- Organizer
  第35回日本救急医学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18591990
[Presentation] Ex vivo and in vivo generation of neutrophil extracellular traps by neutrophils from septic patients.
- Author(s)
  Takeyama N, Huq MA, Ando M, Gocho T, Tomino A, Miyabe H, Kano H, Tsuda M, Hattori T, Hirakawa A, Hashiba M.
- Organizer
  35th International symposium on Intensive Care and Emergency medicine
- Place of Presentation
  Brussels
- Year and Date
  2015-03-17 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24592756
[Presentation] INCREASED PD-1 EXPRESSION AND ALTERED T CELL REPERTOIRE DIVERSITY IN SEPTIC SHOCK PATIENTS
- Author(s)
  N. Takeyama, A. Tomino, M. Hashiba, M. Ando, T. Gocho, H. Miyabe, H. Kano, M. Tsuda, T. Hattori, A. Hirakawa
- Organizer
  38th Shock Society Annual Conference
- Place of Presentation
  Denver
- Year and Date
  2015-06-04 – 2015-06-09
- Invited
- Data Source
  KAKENHI-PROJECT-24592756
[Presentation] 当院の血液浄化の現状
- Author(s)
  服部友紀、武山直志、他
- Organizer
  第42回日本集中治療医学会総会・学術集会,
- Place of Presentation
  東京都ホテル日航東京
- Year and Date
  2015-02-09 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-26462771
[Presentation] A290- Ex vivo and in vivo generation of neutropil extracellular traps by neutrophils from septic patients.
- Author(s)
  Takeyama N, Huq MA, Ando M, Gocho T, Hashiba M, Miyabe H, Kano H, Tomino A, Tsuda M, Hattori T, Hirakawa A
- Organizer
  35th International Symposium on Intensive Care and Emergebcy Medicine
- Place of Presentation
  Brussels, Belgium
- Year and Date
  2015-03-17 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26462771
[Presentation] PMMA-HDFとPMX-DHPを併用施行した敗血症性ショックの治療戦略
- Author(s)
  服部友紀、武山直志、他
- Organizer
  第42回日本救急医学会総会・学術集会
- Place of Presentation
  福岡県福岡市福岡国際会議場
- Year and Date
  2014-10-28 – 2014-10-30
- Data Source
  KAKENHI-PROJECT-26462771
[Presentation] 高度外傷、敗血症時の血漿中circulating free-DNAの動的変化
- Author(s)
  武山直志、加納秀記、中村智之、2
- Organizer
  第40回日本救急医学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23592688

1. KANO Hideki (90340231)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. TSUDA Masanobu (70506683)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. Hata Ryuji (90258153)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 野口宏 (20065569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 富野敦稔 (70440980)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HIRAKAWA Akihiko (00319633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. Hattori Tomonori (90363936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. KITAZAWA Yasuhide (10140261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宮部浩道 (90398363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 竹中信義 (60770534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 森久剛 (10620867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 梶田裕加 (00351099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takeyama Naoshi 武山 直志

TAKEYAMA Naoshi 武山 直志

武山 直志 タケヤマ ナオシ

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Evaluation of gene expression profile during multiple trauma: application of T-iPSPrincipal Investigator

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Stem cell transplantation for vascular permeability and angiogenesis under surgical stressPrincipal Investigator

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Effect of mesenchymal stem cells on septic acute renal failurePrincipal Investigator

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急性肺障害における血管内皮前駆細胞の動態解析:自家移植による再生治療の試みPrincipal Investigator

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CpG oligonucleotides activate the immune response in burned micePrincipal Investigator

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熱傷ストレス下における免疫異常と樹状細胞機能:CpGモチーフによる免疫調整Principal Investigator

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Takeyama Naoshi 武山直志

TAKEYAMA Naoshi 武山直志

武山直志タケヤマナオシ