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MIZUTANI Shigehiko
水谷 榮彦
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Alternative Names
水谷 栄彦 ミズタニ シゲヒコ
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Researcher Number
00159162
Affiliation (based on the past Project Information)
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2002 – 2003: Nagoya University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2001: 名古屋大学, 大学院・医学研究科, 教授
1997 – 2000: Nagoya University, Faculty of Medicine, Professor, 医学部, 教授
1990 – 1996: 名古屋大学, 医学部, 助教授
1988: Nagoya University School of Medicine, 医学部, 助教授
1986: 名大, 医学部, 講師
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
/
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
/
Obstetrics and gynecology
/
Endocrinology
Keywords
Principal Investigator
オキシトシン / アミノペプチダーゼ / ブラジキニン / 妊娠中毒症 / Aminopeptidase / Oxytocinase / Angiotensinase / Oxytocin / アンジオテンシナーゼ / オキシトシナーゼ
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/ アミノペプチダーゼP(AP-P) / アミノペプチダーゼA(AP-A) / P-LAP(オキシトシナーゼ) / パルスドプラー / キニナーゼI / キニナーゼII / アミノペプチダ-ゼM / オキシトシナ-ゼ / クロ-ニング / アンジオテンシナ-ゼ / アミノペプチダ-ゼA / PーLAP / キニナ-ゼI / 胎盤性ロイシン・アミノペプチタ-ゼ / ワゾプレッシン / アンジオテンシン / アミノペプチダ-ゼB / ベスタチン / Placental function test / Placenta / Pregnancy / Angiotensin / 胎盤性ロイシンアミノペプチダーゼ( P-LAP) / ソマトスタチン / 免疫調節ペプチド / 過期妊娠 / 切迫早産 / パルスドプラーS / D比 / 胎盤性ロイシンアミノペプチダーゼ(P-LAP) / cDNA / パゾブレシン / アミノペプチダーゼN(CD13) / スプレノペンチン / サイモペンチン / タフトシン / アミノペプチダーゼP / ヒト胎盤 / 妊娠の免疫調節 / placental leucine aminopeptidase (P-LAP) / oxytocin / vasopressin / somatostatin / angiotensin / angiotensinase / bradykinin / placental function / 分子生物学 / 組み換え蛋白 / 胎盤 / 早産 / アミノペプチダーセ / 遺伝子組み換え / 遺伝子組み換え動物 / 転写 / 免疫染色 / 遺伝子動物 / トランスジェニックマウス / ノックアウトマウス / EIA / ペプチドホルモン / リコンビナントP-LAP / ゲノムクローニング / インヒビター / oxytocinase / molecular biology / recombinant protein / placenta / preterm delivery / aminopeptidase / gene targeting / transgenic animal / 子宮内膜癌 / 絨毛細胞 / 転写因子 / 分化 / 浸潤 / Endometrial Cancer / Trophoblast / Transcription Factor / Differentiation / invasion / 胎盤アミノペプチダーゼ / アンジオテンシン不応性 / 妊娠中毒症治療 / アンジオテンシンレセプター / 遺伝子工学 / レニンーアンギオテンシン / アンジオテンシン代謝 / 高速液体クロマトグラフィー / 胎盤機能評価 / Placental aminopeptidase / Refractoriness to angiotensin II / Pregnancy-induced hypertension / Treatment of pregnancy-induced hypertension / Angiotensin II receptor
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Except Principal Investigator
胎盤 / IUGR / 妊娠中毒症 / Transwell / HGF / 絨毛細胞 / HNE / PSN / プロゲステロン / 産生調節 / 細胞生物学 / 分子生物学 / アクアポリン2 / leucine aminopeptidase / バゾプレシン / 集合尿細管 / オキシトシン / 水再吸収機構 / ペプチダーゼ / 子宮内膜 / 胚着床 / 脱落膜化 / 血管新生 / 着床 / 卵巣過剰刺激症候群 / 予定日超過 / ミトコンドリア遺伝子 / 変異蓄積 / チトクロームオキシダーゼ / DNAコピー / プロモーター / 子定日超過 / 子宮内胎児発育遅延 / チトクロ-ムオキシダ-ゼ / DNAコピ- / プロモ-タ- / placenta / overterm / mitochondria gene / accumulation of mutation / cytochrome oxidase / DNA copy / promotor / 物質輸送 / 胎児肝 / 羊水 / 羊膜 / 細胞増殖 / 胎児肺 / 胎児発育 / トランスフェル / DNA合成 / Transport / Fetal liver / Amniotic fluid / Amnion / Cell proliferation / fetal lung / 特異遺伝子 / 肝細胞増殖因子 / Differential PCR / Preeclampsia / Specific gene / Placenta / hepatocyte growth factor / 脳虚血-再還流 / Ishemic-reperfusion damage in brain / アンギオテンシンII / Extravillous trophoblast / 絨毛癌 / 妊娠高血圧症候群 / Cytotrophoblast / angitensin II / trophoblast / extravillous trophoblast / choriocarcinoma / pregnancy induced hypertension / cytotrophoblast
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Research Projects
(
13
results)
Research Products
(
2
results)
Co-Researchers
(
13
People)
Project Start Year (Newest)
Project Start Year (Oldest)
分泌期子宮内膜のダイナミズムと胚着床・妊娠成立との時間的空間的関連性の解析
Principal Investigator
安藤 寿夫
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
New Development of Oxytocinase Study to Spread through Gynecologic Tumors
Principal Investigator
Principal Investigator
NOMURA Seiji
, 水谷 榮彦
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
A research for the involvement of renin-angiotensin system in placental formation
Principal Investigator
ITAKURA Atsuo
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Saitama Medical School
Nagoya University
Physiological roles of placental leucine aminopeptidase/oxytocinase and its clinical application using molecular biological technique.
Principal Investigator
Principal Investigator
MIZUTANI Shigehiko
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
A Research for Prophylaxis of Ischemia-Reperfusion Damage in the Brain of Neonates during Perinatal Period.
Principal Investigator
ITAKURA Atsuo
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
NAGOYA UNIVERSITY
バゾプレシン感受性水チャンネル(アクアポリン2)の機能発現に関する研究
Principal Investigator
大磯 ユタカ
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Endocrinology
Research Institution
Nagoya University
The study of preeclamptic pregnacy-related gene.
Principal Investigator
KURAUCHI Osamu
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
Physiological significance of human placental aminopeptidases
Principal Investigator
Principal Investigator
MIZUTANI Shigehiko
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
Development of a novel assay system of transplacental transport and study of fetal growth mechanism
Principal Investigator
KURAUCHI Osamu
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
The role of mitochondrial DNA mutation on the aging and dysfunction of placents
Principal Investigator
KURAUCHI Osamu
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
胎盤のプロゲステロン産生調節機構の細胞生物学的・分子生物学的研究
Principal Investigator
KASUGAI Masahide
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
physiological significance of placental aminopeptidases
Principal Investigator
Principal Investigator
MIZUTANI Shigehiko
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
The etiology of pregnancy-induced hypertension based on the degradation of angiotensin II by placental aminopeptidases
Principal Investigator
Principal Investigator
MIZUTANI Shigehiko
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Nagoya University
All
2005
2004
All
Journal Article
Book
[Book] Handbook of Proteolitic enzymes, 2nd edition (Cystinyl aminopeptidase, oxytocinase and insulin-regulated aminopeptidase.)
2004
Author(s)
Nomura S, Tsujimoto M, Mizutani S
Publisher
Academic Press, Elsevier Science
Data Source
KAKENHI-PROJECT-15390503
[Journal Article] Involvement of placental peptidases associated with renin-angiotensin systems in preeclampsia
2005
Author(s)
A.Itakura, S.Mizutani
Journal Title
BBA Proteins and proteomics (掲載予定)
Data Source
KAKENHI-PROJECT-15591740
# of Projects (Dsc)
# of Projects (Asc)
1.
KURAUCHI Osamu
(80195528)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
2.
NOMURA Seiji
(20242860)
# of Collaborated Projects:
4 results
# of Collaborated Products:
1 results
3.
KASUGAI Masahide
(00185787)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
ITAKURA Atsuo
(70262897)
# of Collaborated Projects:
3 results
# of Collaborated Products:
1 results
5.
MURATA Yoshiharu
(80174308)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
TOMODA Yutaka
(60023769)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
TANAKA Masashi
(60155166)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
TSUJIMOTO Masafumi
(00281668)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
KIKKAWA Fumitaka
(40224985)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
OKADA Mayumi
(90324433)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
大磯 ユタカ
(40203707)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
安藤 寿夫
(90273234)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
岩瀬 明
(20362246)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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