Nishihara Shoko 西原祥子

… Alternative Names

NISHIHARA Shoko 西原祥子

西原祥子ニシハラショウコ

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Researcher Number	00164575
Other IDs
Affiliation (Current)	2023: 創価大学, 糖鎖生命システム融合研究所, 教授
Affiliation (based on the past Project Information) *help	2022: 創価大学, 糖鎖生命システム融合研究所, 教授 2020: 創価大学, 糖鎖生命システム融合研究所, 教授 2019: 創価大学, 糖鎖生命システム融合センター, 教授 2015 – 2018: 創価大学, 理工学部, 教授 2012 – 2014: 創価大学, 工学部, 教授 … More 2010: Soka University, 工学部・生命情報工学科 2008 – 2010: Soka University, 工学部, 教授 2001: Soka University, Institute of Life Science, Professor, 生命科学研究所, 教授 1997 – 2000: 創価大学, 生命科学研究所, 助教授 1994: 創価大学, 生命科学研究所, 講師 Less
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Structural biochemistry / Science and Engineering / Hematology / Biological Sciences / Functional biochemistry Except Principal Investigator Molecular biology / Immunology / Bioinformatics/Life informatics / Developmental biology
Keywords	Principal Investigator 糖鎖 / 胚性幹細胞 / ショウジョウバエ / ES細胞 / 分化 / glycosyltransferase / フコース転移酵素 / 糖転移酵素 / 低周波低温大気圧プラズマ / ニッチ … More / 造血幹細胞 / PSME-3 / 液-液相分離 / 多能性幹細胞 / O-GlcNAc / 脂質ラフト / シグナル / マウスES細胞 / プラズマトサイト / クリスタルセル / フィードバック / フィードバック機構 / 成熟血球細胞 / 糖鎖関連遺伝子 / 造血器官 / 活性酸素 / Wntシグナル / FGFシグナル / H2O2 / プラズマ照射 / 幹細胞 / プラズマ医療 / プラズマ照射培地 / 活性窒素 / iPS細胞 / 胚様体形成 / FUT2 / Se enzyme / FUT1 / H enzyme / Golgi apparatus / focosyltransferase / H酵素 / Se酵素 / ゴルジ装置 / fucosyltransferase / Golgi membrane / ガラクトース転移酵素 / ゴルジ膜 / 三胚葉 / エピブラスト / 胚葉体 / 細胞分化 / 胚様体 / 血液幹細胞 / BP102 / 局在 / 近位部 / 初代培養 / 輸送 / BP102抗原 / 区画化 / 軸索 / 神経 / PAPS輸送体 / 発生・分化 / 蛋白質 / 生理機能 / ノックダウン / RNAi / ノックアウトマウス / PAPs輸送体 / 硫酸化 / 糖鎖生物学 … More Except Principal Investigator 糖転移酵素 / フコース転移酵素 / FUCOSYLTRANSFERASE / GLYCOSYLTRANSFERASE / ルイス抗原 / MOLECULAR GENETICS / MOLECULAR BIOLOGY / NEMATODE / C.ELEGANS / 分子遺伝学 / 分子生物学 / 線虫 / C.elegans / フコース転位酵素 / CA19-9 / CARBOHYDRATE / LEWIS ANTIGEN / GALACTOSYLTRANSFERASE / CANCER / SELECTIN / CLA / ガラクトース転移酵素 / シアリルルイスX / セレクチン / 糖鎖構造解析 / 機械学習 / ウイルス / 硫酸化酵素 / 糖鎖インフォマティクス / バイオインフォマティクス / ルイスX抗原 / α1,3フコース転移酵素 / 初期胚抗原 / F9テラトカルシノーマ細胞 / SSEA-1抗原 Less

Functional analysis of O-GlcNAc modification that regulates the liquid-liquid phase separation in pluripotent stem cells.Principal Investigator
- Principal Investigator
  
  西原祥子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Soka University
Determining differentiation from ES cells by localization of signal receptors on the cell membranePrincipal Investigator
- Principal Investigator
  
  Nishihara Shoko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Soka University
Functional screening of glycan-related molecules in feedback regulation of hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Nishihara Shoko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Soka University
ヒトES/iPS細胞の維持と分化におけるプラズマ照射効果と分子生物学的基盤の形成Principal Investigator
- Principal Investigator
  
  西原祥子
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Soka University
ES/iPS細胞の分化におけるプラズマ照射効果とその分子生物学的機構の解明Principal Investigator
- Principal Investigator
  
  西原祥子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Soka University
神経近位部特異的に局在する糖鎖の構造と軸索区画化における機能の解明Principal Investigator
- Principal Investigator
  
  西原祥子
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Soka University
Screening of the glycans regulating stemness and differentiation of hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  NISHIHARA Shoko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Soka University
ウィルスとの結合親和性データからの糖鎖プロファイルの抽出
- Principal Investigator
  
  木下聖子
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Soka University
Analysis of physiological function of su l fat i on by regulating the expression of PAPS transporterPrincipal Investigator
- Principal Investigator
  
  NISHIHARA Shoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Soka University
The molecular system of Golgi retentior of glycosyltransferasesPrincipal Investigator
- Principal Investigator
  
  NISHIHARA Shoko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Soka University
BIOCHEMICAL AND MOLECULAR BIOLOGICAL ANALYSIS OF THE FUCOSYLTRANSFERASES IN C.ELEGANS
- Principal Investigator
  
  KONDO Kazunori
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  SOKA UNIVERSITY
The molecular mechanisms underlying Golgi retention of glycosyltransferasesPrincipal Investigator
- Principal Investigator
  
  NISHIHARA Shoko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Soka University
SEARCH AND IDENFICATION OF NOVEL LIGANDS FOR SELECTINS
- Principal Investigator
  
  NARIMATSU Hisashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  INSTITUTE OF LIFE SCIENCE,SOKA UNICERSITY
初期胚糖鎖抗原-1を生合成するフコース転移酵素のクローニング
- Principal Investigator
  
  NARIMATSU Hisashi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Soka University

[Book] Glycoscience: Biology and Medicine（１章を担当： Functional analysis of glycans using Drosophila mutants and RNAi）2014
- Author(s)
  Fuwa TJ, Nishihara S
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24659468
[Book] The function of glycan structures for the maintenance and differentiation of embryonic stem cells.2011
- Author(s)
  Nishihara, S.
- Publisher
  INTECH(In press)
- Data Source
  KAKENHI-PROJECT-20370051
[Book] Method in Enzymnology(480)(Glycosyltransferases and transporters that contribute to proteoglycan synthesis in Drosophila : Identification and functional analyses using the heritable and inducible RNAi system.)2010
- Author(s)
  西原祥子
- Data Source
  KAKENHI-PROJECT-20370051
[Book] The function of glycan structures expressed on embryonic stem cells.2009
- Author(s)
  西原祥子
- Publisher
  TIGG(21)
- Data Source
  KAKENHI-PROJECT-20370051
[Book] 化学工業(59)(ES細胞の未分化性、多能性維持に関わる硫酸化糖鎖)2008
- Author(s)
  西原祥子
- Data Source
  KAKENHI-PROJECT-20370051
[Book] 蛋白質核酸酵素(53)(糖ヌクレオチド輸送体・PAPS輸送体による糖鎖合成の制御)2008
- Author(s)
  神山伸、西原祥子
- Data Source
  KAKENHI-PROJECT-20370051
[Book] Experimental Glycoscience-Glycobiology(edited by Naoyuki Taniguchi et al.)(Nucleotide sugar transporter genes and their functional analysis.)2008
- Author(s)
  西原祥子
- Publisher
  Springer(Partl, Section III)
- Data Source
  KAKENHI-PROJECT-20370051
[Book] Nucleotide sugar transporter genes and their functional analysis.2008
- Author(s)
  Nishihara, S.
- Publisher
  Experimental Glycoscience-Glycobiology, edited by Naoyuki Taniguchi et al., Springer, Parti, Section III
- Data Source
  KAKENHI-PROJECT-20370051
[Book] Methods Mol. Biol.(Gene silencing in mouse embryonic stem cells.)
- Author(s)
  Sasaki N, Nishihara S
- Publisher
  (in press.)
- Data Source
  KAKENHI-PROJECT-20370051
[Book] Embryonic Stem Cells(The function of glycan structures for the maintenance and differentiation of embryonic stem cells.)
- Author(s)
  西原祥子
- Publisher
  INTECH(in press)
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] Glycans which regulate the stem cell state2020
- Author(s)
  西原祥子
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 94-106
- DOI
  10.14952/SEIKAGAKU.2020.920094
- NAID
  40022176139
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06139
[Journal Article] The functions of O-GlcNAc in pluripotent stem cells2019
- Author(s)
  Miura T, Nishihara S
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 31 Issue: 180 Pages: E69-E75
- DOI
  10.4052/tigg.1954.2e
- NAID
  130007653235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06139
[Journal Article] Cell Profiling Based on Sugar‐Chain?Cell Binding Interaction and Its Application to Typing and Quality Verification of Cells2019
- Author(s)
  Shinchi Hiroyuki、Nakamura Tomoya、Ota Hayato、Nishihara Shoko、Wakao Masahiro、Suda Yasuo
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 14 Pages: 1810-1816
- DOI
  10.1002/cbic.201900028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00929, KAKENHI-PROJECT-18K06139
[Journal Article] Highly sulfated hyaluronic acid maintains human induced pluripotent stem cells under feeder-free and bFGF-free conditions2019
- Author(s)
  Taichi Miura, Noriyuki Yuasa, Hayato Ota, Masato Habu, Mitsuko Kawano, Fumiaki Nakayama, Shoko Nishihara
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 518 Issue: 3 Pages: 506-512
- DOI
  10.1016/j.bbrc.2019.08.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15571, KAKENHI-PROJECT-18K06139
[Journal Article] Glycans in stem cell regulation: from Drosophila tissue stem cells to mammalian pluripotent stem cells2018
- Author(s)
  Shoko Nishihara
- Journal Title
  
  FEBS Letters
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15505
[Journal Article] Glycans in stem cell regulation: from Drosophila tissue stem cells to mammalian pluripotent stem cells.2018
- Author(s)
  Nishihara S.
- Journal Title
  
  FEBS Lett.
  
  Volume: 592 Issue: 23 Pages: 3773-3790
- DOI
  10.1002/1873-3468.13167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06139
[Journal Article] 幹細胞における糖鎖の働き - ショウジョウバエモデルからES細胞まで -2017
- Author(s)
  西原祥子、伊藤和義
- Journal Title
  
  化学と生物
  
  Volume: 55 Pages: 750-758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15505
[Journal Article] Atmospheric pressure plasma irradiation on embryonic stem cells: Signals and differentiation2017
- Author(s)
  Nishihara, S., Ota, H., Miura, T.
- Journal Title
  
  Plasma Medicine
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Journal Article] Atmospheric-pressure plasma-irradiation inhibits mouse embryonic stem cell differentiation to mesoderm and endoderm but promotes ectoderm differentiation2016
- Author(s)
  Miura T, Hamaguchi S, Nishihara S
- Journal Title
  
  J. Phys. D: Appl. Phys.
  
  Volume: 49 Issue: 16 Pages: 165401-165401
- DOI
  10.1088/0022-3727/49/16/165401
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Journal Article] Immuno-Electron Microscopy of Primary Cell Cultures from GeneticallyModified Animals in Liquid by Atmospheric Scanning Electron Microscopy (ASEM)2014
- Author(s)
  T.Kinoshita, Y.Mori, K.Hirano, S.Sugimoto, K.Okuda, S.Matsumoto, T.Namiki, T.Ebihara, M.Kawata, H.Nishiyama, M.Sato, M.Suga, K.Higashiyama, K.Sonomoto, Y.Mizunoe, S.Nishihara, C.Sato
- Journal Title
  
  Microscopy and Microanalysis
  
  Volume: 20 Issue: 2 Pages: 469-483
- DOI
  10.1017/s1431927614000178
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22121004, KAKENHI-PROJECT-23590521, KAKENHI-PROJECT-23689028, KAKENHI-PUBLICLY-24110515, KAKENHI-PROJECT-24780079, KAKENHI-PROJECT-26293100
[Journal Article] Proliferation assay of mouse embryonic stem (ES) cells exposed to atmospheric pressure plasmas at room temperature2014
- Author(s)
  Taichi Miura, Ayumi Ando, Kazumi Hirano, Chika Ogura, Tatsuya Kanazawa, Masamichi Ikeguchi, Atsushi Seki, Shoko Nishihara, and Satoshi Hamaguchi,
- Journal Title
  
  J. Phys. D: Appl. Phys.
  
  Volume: 47 Issue: 44 Pages: 445402-445402
- DOI
  10.1088/0022-3727/47/44/445402
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25108506, KAKENHI-PUBLICLY-25108514
[Journal Article] Expression and role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma.2011
- Author(s)
  Kamiyama S, Ichimiya T, Ikehara Y, Takase T, Fujimoto I, Suda T, Nakamori S, Nakamura M, Nakayama F, Irimura T, Nakanishi H, Watanabe M, Narimatsu N, Nishihara S
- Journal Title
  
  Glycobiology 21
  
  Pages: 235-246
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] Two Golgi-resident 3'-phosphoadenosine 5'-phosphosulfate transporters play distinct roles in heparan sulfate modifications and embryonic and larval development in Caenorhabditis elegans.2010
- Author(s)
  Dejima K, Murata D, Mizuguchi S, Nomura KH, Izumikawa T, Kitagawa H, Gengyo-Ando K, Yoshina S, Ichimiya T, Nishihara S, Mitani S, Nomura K
- Journal Title
  
  J Biol.Chem. 285
  
  Pages: 24717-24728
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] Chemical inhibition of sulfation accelerates neural differentiation of mouse embryonic stem cells and human induced pluripotent stem cells.2010
- Author(s)
  Sasaki N, Hirano T, Kobayashi K, Toyoda M, Miyakawa Y, Okita H, Kiyokawa N, Akutsu H, Umezawa A, Nishihara S
- Journal Title
  
  BBRC 401
  
  Pages: 480-486
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] Glycosyltransferases and transporters that contribute to proteoglycan synthesis in Drosophila : Identification and functional analyses using the heritable and inducible RNAi system.2010
- Author(s)
  Nishihara, S.
- Journal Title
  
  Method in Enzymnology
  
  Volume: 480 Pages: 323-351
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] The function of glycan structures expressed on embryonicstem cells2009
- Author(s)
  Nishihara, S.
- Journal Title
  
  TIGG 21
  
  Pages: 207-218
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells.2009
- Author(s)
  Sasaki N, Hirano T, Ichimiya T, Wakao M, Hirano K, Kinoshita-Toyoda A, Tovoda H, Suda Y, Nishihara S
- Journal Title
  
  PLoS One 4
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] ES細胞の未分化性、多能性維持に関わる硫酸化糖鎖.2008
- Author(s)
  西原祥子
- Journal Title
  
  化学工業 59
  
  Pages: 947-954
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.2008
- Author(s)
  Sasaki N, Okishio K, Ui-Tei K, Saigo K, Kinoshita-Toyoda A, Tovoda H, Nishimura T, Suda Y, Hayasaka M, Hanaoka K, Hitoshi S, Ikenaka K, Nishihara S
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 3594-3606
- Data Source
  KAKENHI-PROJECT-20370051
[Patent] 胚様体を外胚葉へと分化誘導する方法2015
- Inventor(s)
  西原祥子、三浦太一、浜口智志
- Industrial Property Rights Holder
  学校法人創価大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-231156
- Filing Date
  2015-11-26
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Patent] 神経細胞の製造方法及び神経細胞分化促進剤2010
- Inventor(s)
  西原祥子、佐々木紀彦
- Industrial Property Rights Holder
  西原祥子、佐々木紀彦
- Industrial Property Number
  2010-223472
- Filing Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-20370051
[Patent] 胚様体分化制御剤2010
- Inventor(s)
  西原祥子、佐々木紀彦
- Industrial Property Rights Holder
  西原祥子、佐々木紀彦
- Industrial Property Number
  2010-261170
- Filing Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-20370051
[Patent] 分化制御剤、分化抑制基材及び分化抑制方法並びにその使用2010
- Inventor(s)
  西原祥子、佐々木紀彦
- Industrial Property Rights Holder
  西原祥子、佐々木紀彦
- Industrial Property Number
  2008-167493
- Filing Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20370051
[Patent] 胚様体分化制御剤2009
- Inventor(s)
  西原祥子, 佐々木紀彦
- Industrial Property Rights Holder
  学校法人創価大学、タマティーエルオー株式会社
- Industrial Property Number
  2009-267231
- Filing Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-20370051
[Patent] 胚様体分化制御剤2009
- Inventor(s)
  西原祥子、佐々木紀彦
- Industrial Property Rights Holder
  西原祥子、佐々木紀彦
- Industrial Property Number
  2009-267231
- Filing Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-20370051
[Patent] 分化制御剤、分化抑制基材及び分化抑制方法並びにその使用2008
- Inventor(s)
  西原祥子, 佐々木紀彦
- Industrial Property Rights Holder
  出願人 : 学校法人創価大学, タマティーエルオー株式会社
- Industrial Property Number
  2008-167493
- Filing Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Mucin-type O-glycosylation regulates pluripotency in mouse embryonic stem cell2019
- Author(s)
  Pecori F, Hanamatsu H, Furukawa J, Nishihara S
- Organizer
  The ISSCR (International Society for Stem Cell Research) 18th Annual Meeting, Los Angeles, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] Functional analyses of glycans in mammalian stem cells2019
- Author(s)
  Nishihara S, Miura T, Ota H, Yuasa N, Habu M, Pecori F, Nakayama F, Ogura C
- Organizer
  11th Asian Community of Glycoscience and Glycotechnology Conference, Busan, South Korea, South Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] 多能性幹細胞におけるヘパラン硫酸とO-GlcNAc修飾によるシグナル制御2019
- Author(s)
  西原祥子
- Organizer
  第92回日本生化学会大会、横浜
- Invited
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] O-GlcNAc inhibits FGF4 signaling via inhibition of PKC zeta phosphorylation to maintain naive state in mouse embryonic stem cells.2019
- Author(s)
  Nishihara S
- Organizer
  Glycobiology Gordon Research Conference, Lucca (Barga), IT.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] Function of glycans in pluripotent stem cells2019
- Author(s)
  Nishihara S, Miura T, Ota H, Yuasa N, Habu M, Pecori F, Nakayama F, Ogura C
- Organizer
  1st International Symposium on Glycans,Zhuhai, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] bFGFおよびフィーダー細胞を必要としない高硫酸化ヒアルロン酸を用いたヒトiPS細胞の新規培養法の確立2019
- Author(s)
  三浦太一、湯浅徳行、太田隼人、羽生正人、川野光子、中山文明、西原祥子
- Organizer
  第42回日本分子生物学会年会、福岡
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] O-GlcNAc on PKCζ inhibits differentiation of mouse embryonic stem cells2019
- Author(s)
  Pecori F, Ota H, Miura T, Nishihara S
- Organizer
  The 25th International Symposium on Glycoconjugates (GLYCO XXV), Milano, Italy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] マウスES細胞におけるO-GlcNAc糖鎖修飾による新規FGF4シグナル抑制機構2019
- Author(s)
  三浦太一、中山文明、西原祥子
- Organizer
  第18回日本再生医療学会総会、神戸
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] 幹細胞における糖鎖の機能2018
- Author(s)
  西原祥子
- Organizer
  第12回多糖の未来フォーラム、京都
- Invited
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] O-GlcNAc Regulates Signaling in Embryonic Stem Cells.2018
- Author(s)
  Nishihara S
- Organizer
  the 24th IUBMB Congress & 15th FAOBMB Congress, Seoul, Korea.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06139
[Presentation] プラズマ照射によるES細胞の分化制御効果：各種シグナル経路の活性化と抑制2016
- Author(s)
  西原祥子
- Organizer
  第57回日本組織細胞化学会総会・学術集会　シンポジウム
- Place of Presentation
  東京
- Year and Date
  2016-09-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Presentation] Effects of low-temperature atmospheric-pressure plasma irradiation on mouse embryonic stem cells2016
- Author(s)
  Nishihara S, Miura T, Hamaguchi S
- Organizer
  5th International Conference on Advanced Plasma Technologies
- Place of Presentation
  Zrece, Slovenia
- Year and Date
  2016-02-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Presentation] Atmospheric-pressure plasma irradiation on embryonic stem cells: signals and differentiation2016
- Author(s)
  Nishihara S
- Organizer
  6th International Conference on Plasma Medicine (ICPM-6)
- Place of Presentation
  Bratislava, Slovakia
- Year and Date
  2016-09-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Presentation] プラズマ照射のES細胞の分化への影響2015
- Author(s)
  西原祥子
- Organizer
  新学術領域研究「プラズマ医療科学の創成」＋「統合的神経機能の制御を標的とした糖鎖の作動原理解明」合同公開シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2015-08-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H00904
[Presentation] The atmospheric scanning electron microscope (ASEM) observes axonal segmentation and synaptic induction in solution2014
- Author(s)
  Sato C, Kinoshita T, Uemura T, Hiarno K, Kawata M, Nishiyama H, Sato M, Ebihara T, Suga M, Nishihara S
- Organizer
  Microscopy & Microanalysis 2014 Meeting
- Place of Presentation
  Hartford
- Data Source
  KAKENHI-PUBLICLY-24110515
[Presentation] Analysis of intra-axonal compartmentalization in Drosophila neuron by Atmospheric Scanning Electron Microscopy (ASEM)2014
- Author(s)
  Kinoshita T, Fuwa T, Sato T, Nishihara S
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PUBLICLY-24110515
[Presentation] Effects of low-temperature atmospheric-pressure plasma irradiation on the differentiation of mouse embryonic stem cells2014
- Author(s)
  Miura T, Ogura C, Hamaguchi S, Nishihara S
- Organizer
  5th International Conference on Plasma Medicine (ICPM5)
- Place of Presentation
  Nara
- Data Source
  KAKENHI-PUBLICLY-25108514
[Presentation] The atmospheric scanning electron microscope (ASEM) observes axonal segmentation and platelet generation in solution2014
- Author(s)
  Kinoshita T, Motohashi H, Hirano K, Maruyama Y, Kawata M, Ebihara T, Sato M, Nishiyama H, Suga M, Yamamoto M, Nishihara S, Sato C
- Organizer
  The 18th International Microscopy Congress
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PUBLICLY-24110515
[Presentation] Effects of reactive species generated by low-temperature atmospheric-pressure plasmas on mouse embryonic stem (ES) cells.2013
- Author(s)
  Miura T, Ando A, Hirano K, Ogura C, Kanazawa T, Ikeguchi M, Nishihara S, Hamaguchi S
- Organizer
  2013 JSAP-MRS Joint Symposia
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PUBLICLY-25108514
[Presentation] 糖鎖異常に起因する疾患のショウジョウバエモデルを用いた解析: 筋ジストロフィー2012
- Author(s)
  西原祥子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-24110515
[Presentation] 硫酸化阻害剤によるマウスES細胞およびヒトips細胞の神経分化誘導2011
- Author(s)
  小林久美子、佐々木紀彦、平野拓也、豊田雅士、梅澤明弘、西原祥子
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation]2010
- Author(s)
  Nishihara, S.
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Makuhari
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Sulfation contributes to the maintenance of mouse embryonic stem cells, the differentiation of the embryoid body and the progression of neurogenesis2010
- Author(s)
  Sasaki N, Hirano T, Ichimiya T, Wakao M, Hirano K, Kinoshita-Toyoda A, Toyoda H, Suda Y, Nishihara S
- Organizer
  第8回幹細胞シンポジウム
- Place of Presentation
  淡路
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] 硫酸化修飾はES細胞の維持および分化に重要である2010
- Author(s)
  佐々木紀彦、平野拓也、一宮智美、平野和己、隅田康生、豊田英尚、西原祥子
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Functional analysis of sulfated glycans in the differentiation of embryonic stem cells2010
- Author(s)
  Nishihara S, Sasaki N, Hirano T, Ichimiya T, Hirano K, Toyoda H, Suda Y
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Makuhari
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Sulfated glycan function in development : from Drosophila to ES cells.2010
- Author(s)
  Nishihara, S.
- Organizer
  The 8th Naito Conference on Glycan Expression and Regulation [I]
- Place of Presentation
  Kanagawa
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] ES細胞の未分化性・多能性維持、分化シグナルの拠点となる硫酸化糖鎖2010
- Author(s)
  西原祥子、佐々木紀彦、平野和己、隅田泰生、豊田英尚、一宮智美
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)ワークショップ
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Expression and role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma2010
- Author(s)
  神山伸、一宮智美、池原譲、中森正二、中村充、中山文明、入村達郎、中西速夫、渡邊昌彦、成松久、西原祥子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Sulfated glycan function in development : from Drosophila to ES cells2010
- Author(s)
  西原祥子
- Organizer
  The 8th Naito Conference on Glycan Expression and Regulation [I] Functions and Disease Mechanisms
- Place of Presentation
  Kanagawa
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and PAPST2, are important for the maintenance and the differentiation of mouse embryonic stem cells2009
- Author(s)
  Nishihara S, Sasaki N, Hirano T, Ichimiya T, Wakao M, Kinoshita-Toyoda A, Tovoda H, Suda Y.
- Organizer
  XX International Symposium on Glycoconjugates
- Place of Presentation
  San Juan (Puerto Rico)
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] マウスPAPS輸送体mPAPST1, mPAPST2の機能解析2009
- Author(s)
  幾世高史、一宮智美、藤本泉、尾崎秀徳、工藤墨、中村充、西原祥子
- Organizer
  GlycoTOKYO2009シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] The 3' -phosphoadenosine 5' -phosphosulfate transporters, PAPST1 and PAPST2, are important for the maintenance and the differentiation of mouse embryonic stem cells2009
- Author(s)
  西原祥子
- Organizer
  XX International Symposium on Glycoconjugates
- Place of Presentation
  San Juan(Puerto Rico)
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] ES細胞の未分化性・多能性維持に関わる硫酸化糖鎖2009
- Author(s)
  西原祥子、佐々木紀彦、平野和己
- Organizer
  第32回日本分子生物学会年会、ワークショップ
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] PAPST1抑制によるBurkittリンパ腫細胞の放射線感受性の増加について2009
- Author(s)
  中山文明、梅田禎子、神山伸、一宮智美、西原祥子、明石真言
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Heparan suliate regulates self-renewal and pluripotency of mouse embryonic stem cells.2008
- Author(s)
  Nishihara, S.
- Organizer
  The 6th International Symposium on Glycosyltransferases
- Place of Presentation
  Atlanta (USA)
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Heparansulfate regulates self-renewal and pluripotency of embryonic stem cells2008
- Author(s)
  Sasaki N, Okishio K, Ui-Tei K, Kinoshita-Toyoda A, Toyoda H, Nishimura T., Suda Y, Hayasaka M, Hanaoka K, Nishihara S
- Organizer
  The 23rd Naito Conference on Molecular Basis for Maintenance and Differentiation of Stem Cells
- Place of Presentation
  Kanagawa
- Data Source
  KAKENHI-PROJECT-20370051
[Presentation] Effects of low-temperature atmospheric-pressure plasma irradiation on the differentiation of mouse embryonic stem cells.
- Author(s)
  Miura T, Ogura C, Hamaguchi S, Nishihara S
- Organizer
  5th International Conference on Plasma Medicine (ICPM5)
- Place of Presentation
  Nara
- Year and Date
  2014-05-18 – 2014-05-23
- Data Source
  KAKENHI-PUBLICLY-25108514
[Presentation] Effect of low-temperature atmospheric-pressure plasma irradiation on the proliferation and differentiation of mouse embryonic stem cells.
- Author(s)
  Miura T, Ogura C, Hamaguchi S, Nishihara S
- Organizer
  The 2nd International Workshop on Plasma for Cancer Treatment
- Place of Presentation
  Nagoya
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PUBLICLY-25108514

1. NARIMATSU Hisashi (40129581)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. KUDO Takashi (20288062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 伊藤和義

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. TOYODA Hidenao (70217579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. ONO Masaya (00270900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUWA Takashi (50570719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. KONDO Kazunori (10211913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 木下聖子 (50440235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高瀬明 (60236221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 栂谷内晶 (60392635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 吉池健治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤大一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 符敦賢

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAWATA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 佐藤主税

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 浜口智志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 隅田泰生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 新地浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 三浦太一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishihara Shoko 西原 祥子

NISHIHARA Shoko 西原 祥子

西原 祥子 ニシハラ ショウコ

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Co-Researchers

Functional analysis of O-GlcNAc modification that regulates the liquid-liquid phase separation in pluripotent stem cells.Principal Investigator

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Determining differentiation from ES cells by localization of signal receptors on the cell membranePrincipal Investigator

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Functional screening of glycan-related molecules in feedback regulation of hematopoietic stem cellsPrincipal Investigator

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ヒトES/iPS細胞の維持と分化におけるプラズマ照射効果と分子生物学的基盤の形成Principal Investigator

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ES/iPS細胞の分化におけるプラズマ照射効果とその分子生物学的機構の解明Principal Investigator

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神経近位部特異的に局在する糖鎖の構造と軸索区画化における機能の解明Principal Investigator

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Screening of the glycans regulating stemness and differentiation of hematopoietic stem cellsPrincipal Investigator

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ウィルスとの結合親和性データからの糖鎖プロファイルの抽出

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Analysis of physiological function of su l fat i on by regulating the expression of PAPS transporterPrincipal Investigator

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The molecular system of Golgi retentior of glycosyltransferasesPrincipal Investigator

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BIOCHEMICAL AND MOLECULAR BIOLOGICAL ANALYSIS OF THE FUCOSYLTRANSFERASES IN C.ELEGANS

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The molecular mechanisms underlying Golgi retention of glycosyltransferasesPrincipal Investigator

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SEARCH AND IDENFICATION OF NOVEL LIGANDS FOR SELECTINS

Principal Investigator

Nishihara Shoko 西原祥子

NISHIHARA Shoko 西原祥子

西原祥子ニシハラショウコ