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HYAKUSOKU Hiko  百束 比古

ORCIDConnect your ORCID iD *help
Researcher Number 00165135
Affiliation (based on the past Project Information) *help 2012: 日本医科大学, 医学(系)研究科(研究院), 教授
2012: 日本医科大学, 医学研究科, 教授
2010 – 2011: 日本医科大学, 大学院・医学研究科, 教授
2008: 日本医科大学, 医学研究科, 教授
2003 – 2008: 日本医科大学, 大学院・医学研究科, 教授 … More
2006: 日本医科大学, 大学院医学研究科, 教授
2004: Nippon Medical School, Medical Science, Professor, 大学院医学研究科, 教授
2000 – 2003: 日本医科大学, 医学部, 教授 Less
Review Section/Research Field
Principal Investigator
Plastic surgery / Plastic surgery
Except Principal Investigator
Plastic surgery / Plastic surgery
Keywords
Principal Investigator
DNA-MICROARRAY / EXTRACELLULAR MATRIX / REAL-TIME PCR / HYPERTROPHIC SCARS / KELOIDS / 細胞増殖 / SNP / 肥厚性瘢痕 / ケロイド / 脂肪 … More / 再生医学 / tissue engineering / regenerative medicine / vessels / bone / adipose tissue / mesenchymal stem cells / 軟骨 / トランスレーショナルリサーチ / 組織工学 / 血管 / 骨 / 間葉系幹細胞 / PROTEOGALYCANS / PAR-1 / II-24 / マイクロビーズ・アレイ / Decorin / TGF-β1 / Mda-7 / Par-1 / c-erb B / Real-Time PCR / promoter領域 / collagen形成 / microarray解析 / decorin / lumican / ケロイド培養線維芽細胞 / PROTEOGLYCANS / PATHOLOGICAL GENOMICS / TUMOR SUPPRESSORS / HYPERTROPHIC SCAR / KELOID / apoptosis / PCR / NMR / 遺伝子多型性 / p53遺伝子 / Pathological Genomics / 分子病態 / 腫瘍抑制遺伝子 / DNA-microarray / 顎骨 / 水平性骨吸収 / 頭蓋骨欠損モデル / α-TCP / β-TCP / 多血小板血漿 / 骨増生 / 脂肪組織幹細胞 / 遺伝子導入 / トランスジェニックマウス / GFP / トランスジェニック動物 … More
Except Principal Investigator
組織工学 / 再生医学 / 脂肪 / 間葉系幹細胞 / tissue engineering / regenerative medicine / adipose tissue / mesenchymal stem cells / 脂肪組織 / periodontal diseases / periodontal tissue / 歯周病 / 歯周組織 / skin / 皮膚 / cartilage / stem cells / 軟骨 / 幹細胞 / Tissue Engineering / Regenerative Medicine / Fat / Mesenchymal stem cells / 血管内皮細胞 / 増殖因子 / 血管新生 / 脂肪組織幹細胞 Less
  • Research Projects

    (10 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (14 People)
  •  Horizontal bony outgrowth for mandibular bone using tissue engineering technologyPrincipal Investigator

    • Principal Investigator
      HYAKUSOKU Hiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Mechanism of angiogenesis induced by adipose-derived stem cells

    • Principal Investigator
      MIZUNO Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  緑色脂肪トランスジェニックマウスの開発Principal Investigator

    • Principal Investigator
      百束 比古
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  3 dimensional tissue regeneration using adipose-derived stem cells in large animal modelPrincipal Investigator

    • Principal Investigator
      HYAKUSOKU Hiko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Periodontal tissue regeneration by adipose derived stem cells

    • Principal Investigator
      MIZUNO Hiroshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Therapeutic approach for refractory skin ulcers by adipose derived stem cells

    • Principal Investigator
      IWAKIRI Itaru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  In vivo 3 dimensional cartilage tissue engineering by adipose derived stem cells

    • Principal Investigator
      MURAKAMI Masahiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Genomics Study on Keloids and Hypertrophic ScarsPrincipal Investigator

    • Principal Investigator
      HYAKUSOKU Hiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  3 dimensional fat regeneration using Adipose derived stem cells

    • Principal Investigator
      MIZUNO Hiroshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Genomic Study on Keloids and Hypertrophic ScarsPrincipal Investigator

    • Principal Investigator
      HYAKUSOKU Hiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      NIPPON MEDICAL SCHOOL

All 2013 2012 2011 2009 2008 2007 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] Tissue engineering using adipose-derived stem cells harvested from GFP transgenic animals 「New Developments in Stem Cell Research」(Editor : Erik V.Grier)2007

    • Author(s)
      Ogawa R, Fujimura J, Mizuno H, Hyakusoku H and Shimada T
    • Publisher
      NOVA Science publishers, New York(分担)
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Journal Article] Effect of adipose-derived stem cells on improving the viability of diced cartilage graft2011

    • Author(s)
      Orbay H, Tobita M, Hyakusoku H, Mizuno H
    • Journal Title

      Plast Reconstr Surg

      Volume: 129 Pages: 369-377

    • Data Source
      KAKENHI-PROJECT-22592005
  • [Journal Article] Periodontal tissue regeneration with adipose-derived stem cells2008

    • Author(s)
      Tobita M, Uysal AC, Ogawa R, Hyakusoku H and Mizuno H
    • Journal Title

      Tissue Eng 14(6)

      Pages: 945-953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Journal Article] Improved viability of random pattern skin flaps through the use of adipose-derived stem cells2008

    • Author(s)
      Lu F, Mizuno H, Uysal AC, Cai X, Ogawa R and Hyakusoku H
    • Journal Title

      Plast Reconstr Surg 121(1)

      Pages: 50-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Journal Article] In vivo adipose tissue regeneration by adipose-derived stromal cells isolated from GFP transgenic mice2008

    • Author(s)
      Mizuno H, Itoi Y, Kawahara S, Ogawa R, Akaishi S and Hyakusoku H
    • Journal Title

      Cells Tissues Organs 187(3)

      Pages: 177-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Journal Article] Pathological Genomics of Keloid Fibroblastic Cells2005

    • Author(s)
      Wang CM, Hyakusoku H, et al.
    • Journal Title

      Chinese J Plastic Reconstructive Surgery (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Pathological Genomics of Keloid Fibroblastic Cells2005

    • Author(s)
      Wang CM, Hyakusoku H, et al.
    • Journal Title

      Chinese J Plastic Reconstructive Surgery (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Severe Neck Scar Contricture Reconstructed with a Ninth Dorsal Inter2004

    • Author(s)
      Ogawa R, Hyakusoku H, et al.
    • Journal Title

      Annals of Plastic Surgery 52

      Pages: 216-219

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] ケロイド・肥厚性瘢痕の治療とシリコーン・ジェルシート2004

    • Author(s)
      大浦武彦, 百束比古, 他
    • Journal Title

      ibid 20(4)

      Pages: 439-457

    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] ケロイド・肥厚性瘢痕に対するシリコーン・ジェルシートの使用経験(1)2004

    • Author(s)
      小川令, 赤石諭史, 百束比古
    • Journal Title

      臨床医薬 20(4)

      Pages: 459-464

    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Severe Neck Scar Contracture Reconstructed with a Ninth Dorsal Inter2004

    • Author(s)
      Ogawa R, Hyakusoku H, et al.
    • Journal Title

      Annals of Plastic Surgery 52

      Pages: 216-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Postoperative Electron-beam Irradiation Therapy for Keloids and Hypertrophic Scars2003

    • Author(s)
      Ogawa R, Hyakusoku H, et al.
    • Journal Title

      Plastic and Reconstruction Surgery 111

      Pages: 547-553

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Reconstruction of axillary scar constrictures-retrospective study2003

    • Author(s)
      Ogawa R, Hyakusoku H, et al.
    • Journal Title

      British J Plastic Surgery 56

      Pages: 100-105

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] The Small-wave Incision for long Keloids2003

    • Author(s)
      Hyakusoku H, Ogawa R
    • Journal Title

      Plastic and Reconstruction Surgery 111

      Pages: 964-965

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Reconstruction of axillary scar constrictures - retrospective study2003

    • Author(s)
      Ogawa R, Hyakusoku H, et al.
    • Journal Title

      British J Plastic Surgery 56

      Pages: 100-105

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370574
  • [Journal Article] Prefabrication of tissue engineered bone grafts : an experimental study

    • Author(s)
      Okuda T, Uysal AC, Tobita M, Hyakusoku H and Mizuno H
    • Journal Title

      Ann Plast Surg (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Journal Article] The effect of adipose-derived stem cells on ischemia reperfusion

    • Author(s)
      Uysal AC, Ogawa R, Tobita M, Hyakusoku H and Mizuno H
    • Journal Title

      injury : immunohistochemical and ultrastructural evaluation Plast Reconstr Surg (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Journal Article] Comparison of readily available scaffolds for adipose tissue engineering using adipose-derived

    • Author(s)
      Itoi Y, Takatori M, Hyakusoku H and Mizuno H
    • Journal Title

      J Plast Reconstr Aesthet Surg (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] ラット頭蓋骨における脂肪組織幹細胞と多血小板血漿による骨再生能の免疫学的検証2013

    • Author(s)
      田島聖士、飛田護邦、ハカンオルバイ、百束比古、水野博司
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      神奈川・日本
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-22592005
  • [Presentation] 多血小板血漿を移植キャリアーとして用いた脂肪組織幹細胞の硬組織再生能2012

    • Author(s)
      飛田護邦、田島聖士、ハカンオルバイ、百束比古、水野博司
    • Organizer
      第4回PRP療法研究会
    • Place of Presentation
      大阪・日本
    • Year and Date
      2012-11-25
    • Data Source
      KAKENHI-PROJECT-22592005
  • [Presentation] ラット頭蓋骨における脂肪組織幹細胞と多血小板血漿を用いた硬組織再生への効果2012

    • Author(s)
      飛田護邦、田島聖士、ハカンオルバイ、百束比古、水野博司
    • Organizer
      第42回日本創傷治癒学会
    • Place of Presentation
      北海道・日本
    • Year and Date
      2012-12-04
    • Data Source
      KAKENHI-PROJECT-22592005
  • [Presentation] 幹細胞より誘導した再生骨に対しprefabrication手法を用いて血管導入された組織移植に関する研究2009

    • Author(s)
      奥田貴久、A. Cagri Uysal、Hakan Orbay、河邊京子、小野真平、糸井由里恵、百束比古、水野博司
    • Organizer
      第1回日本創傷外科学会
    • Place of Presentation
      東京
    • Year and Date
      2009-01-17
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] Therapeutic strategy for chronic wound by stem cells or controlled-release of basic fibroblast growth factors2008

    • Author(s)
      Mizuno H, Hyakusoku H, Miyamoto M and Tabata Y
    • Organizer
      International Conference on Advances in Bioresorbable Biomaterials for Tissue Engineering
    • Place of Presentation
      Singapore
    • Year and Date
      2008-01-06
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] Clinical perspective of the stem cell therapy in the field of plastic surgery2008

    • Author(s)
      Mizuno H, Uysal AC, Tobita M, Itoi Y, Hyakusoku H and Nambu H
    • Organizer
      The 9^<th> Japan-Korean Congress of Plastic and Reconstructive Surgery
    • Place of Presentation
      沖縄
    • Year and Date
      2008-02-22
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] Adipose derived stem cells accelerate primary nerve repair2008

    • Author(s)
      Mizuno H, Uysal AC, Orbay H, Okuda T and Hyakusoku H
    • Organizer
      6^<th> Annual Meeting of International Federation of Adipose Therapeutics and Science
    • Place of Presentation
      oulouse, France 2008
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] prefabricated flapを用いた再生培養骨への血管付加2008

    • Author(s)
      奥田貴久、A. Cagri Uysal、糸井由里恵、河邊京子、小野真平、Hakan Orbay、百束比古、水野博司
    • Organizer
      第17回日本形成外科学会基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-02
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] Flap prefabrication technique as a tool for inducing angiogenesis in tissue engineering2008

    • Author(s)
      Okuda T, Tobita M, Uysal AC, Ogawa R, Hyakusoku H and Mizuno H
    • Organizer
      3^<rd> Annual Meeting of the Plastic Surgery Research Council
    • Place of Presentation
      Splingfield, IL
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] The effect of stem cells on acute wound healing Tissue Engineering2007

    • Author(s)
      Uysal AC, Mizuno H, Tobita M and Hyakusoku H
    • Organizer
      International & Regenerative Medicine Society Asia-Pacific Chapter Meeting 2007
    • Place of Presentation
      東京
    • Year and Date
      2007-12-05
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] The effect of stem cells on skin flap models : random skin flap, prefabricated skin flap, ischemia reperfusion injury model, expanded skin flap2007

    • Author(s)
      Uysal AC, Mizuno H, Ogawa R, Lu F, Tobita M and Hyakusoku H
    • Organizer
      The 14^<th> international congress of the international confederation for plastic, reconstructive and aesthetic surgery
    • Place of Presentation
      Berlin
    • Year and Date
      2007-06-28
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] Angiogenic potential of adipose-derived stem cells in skin flap model2007

    • Author(s)
      Mizuno H, Uysal AC, Lu F, Ogawa R and Hyakusoku H
    • Organizer
      Tissue Engineering International & Regenerative Medicine Society Asia-Pacific Chapter Meeting 2007
    • Place of Presentation
      東京
    • Year and Date
      2007-12-05
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] The effect of stem cells on acute wound healing2007

    • Author(s)
      Uysal AC, Mizuno H, Nambu M, Tobita M and Hyakusoku H
    • Organizer
      5^<th> Annual Meeting of International Federation of Adipose Therapeutics and Science
    • Place of Presentation
      Indianapolis, Indiana
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] Adipose derived stem cells as a novel source of cell-based therapy in vivo2007

    • Author(s)
      Mizuno H, Uysal AC, Tobita M, Itoi Y, Ogawa R, Nambu M, and Hyakusoku H
    • Organizer
      The 14^<th> international congress of the international confederation for plastic, reconstructive and aesthetic surgery
    • Place of Presentation
      Berlin
    • Year and Date
      2007-06-28
    • Data Source
      KAKENHI-PROJECT-19592080
  • [Presentation] 拡張された皮弁に対する脂肪組織幹細胞の影響2007

    • Author(s)
      A. Cagri Uysal、水野博司、飛田護邦、糸井由里恵、百束比古
    • Organizer
      第16回日本形成外科学会基礎学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19592080
  • 1.  MIZUNO Hiroshi (80343606)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 23 results
  • 2.  MURAKAMI Masahiro (00239500)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  OGAWA Rei (70398866)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KOIKE Sachiko (90386227)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NAKAZAWA Nando (20010051)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  OKI Koichiro (90291715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  AKAISHI Satoshi (10373010)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TOBITA Morikuni (10599038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 9.  IGOTA Shinichi (30339361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IWAKIRI Itaru (50307899)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  AOKI Ritsu (50231775)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  石丸 さやか (00297889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  河原 理子 (30328794)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ONO Shimpei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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