SAKATA Nobuo 坂田宣夫

Researcher Number	00170598
Other IDs	https://orcid.org/0000-0001-9967-8409
Affiliation (based on the past Project Information) *help	2013 – 2014: 昭和薬科大学, 薬学部, 講師 2002 – 2003: 昭和薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Experimental pathology / Pathological medical chemistry
Keywords	Principal Investigator ZFH4 / ATBF1 / Central nervous System / Zinc Finger / Homeodomain / 中枢神経 / ジンクフィンガー / ホメオドメイン / スプライソソーム / シグナル伝達研究の新展開 … More / JMJD6 / LUC7L3 / Smad / Alternative splicing Less

Smad-mediated spliceosome assembly and alternative splicingPrincipal Investigator
- Principal Investigator
  
  SAKATA Nobuo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa Pharmaceutical University
EXPRESSION ANALYSIS OF TRANSCRIPTION FACTOR, ATBF1 AND ZFH4 IN NORMAL DEVELOPING RAT BRAINPrincipal Investigator
- Principal Investigator
  
  SAKATA Nobuo, 川口誠
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  SHOWA PHARMACEUTICAL UNIVERSITY
  Toyama Medical and Pharmaceutical University

All 2014 2013 Other

All Journal Article Presentation

[Journal Article] TGF-β signaling cooperates with AT motif-binding factor-1 for repression of the α-fetoprotein promoter.2014
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Journal Title
  
  J. Signal Transduct.
  
  Volume: 2014 Pages: 970346-970346
- DOI
  10.1155/2014/970346
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006
[Journal Article] C18ORF1: A Novel Negative Regulator of TGF-β Signaling.2014
- Author(s)
  2. Nakano N, Maeyama K, Ikeno S, Itoh F, Togawa Y, Katsu Y, Thanh Thao, VN, Watanabe Y, Kato M & Itoh, S.
- Journal Title
  
  J. Biol. Chem.,
  
  Volume: 289 Issue: 18 Pages: 12680-12680
- DOI
  10.1074/jbc.m114.558981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-25118728, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state.2013
- Author(s)
  Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray M, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, Nishimura R, Sakata N, Fine HA, Carpenter AE, Silver SJ, Verhaak RGW, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG
- Journal Title
  
  Cell Reports
  
  Volume: 6 Issue: 2 Pages: 1-12
- DOI
  10.1016/j.celrep.2013.12.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659824, KAKENHI-PROJECT-25293378, KAKENHI-PROJECT-25670168
[Presentation] 転写因子ATBF1とTGF-βシグナル伝達系によるalpha-fetoprotein遺伝子プロモーターの協調的抑制2014
- Author(s)
  坂田宣夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
- Organizer
  第58回日本薬学会関東支部会
- Place of Presentation
  昭和薬科大学（町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] TMEPAIファミリーによるTGF-βシグナル制御機構2014
- Author(s)
  中野なおこ、赤津俊介、中田美紀、伊東史子、坂田宣夫、葛祐紀、池野聡一、戸川陽子、伊東進
- Organizer
  第58回日本薬学会関東支部会
- Place of Presentation
  昭和薬科大学（町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] Transcriptional Repression Mechanisms of TGF-β Signaling and ATBF1 on the AFP Promoter
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  Joint International Symposium on TGF-β Family and Cancer “Signal Network in Tumor Microenvironment”
- Place of Presentation
  つくば国際会議場（つくば市）
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] TGF-β Signaling Cooperates with AT Motif Binding Factor 1 (ATBF1) to Repress α-Fetoprotein Gene in Human Hepatoma Cells.
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] Negative regulation of α-fetoprotein gene transcription by TGF-β signaling with AT motif binding factor 1 (ATBF1)
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  TGF-β Meeting in Leiden 2014 “TGF-β signal transduction in human disease”
- Place of Presentation
  Leiden Univ. Med. Center (Leiden, NL)
- Year and Date
  2014-05-07 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] 2.TGF-β signaling cooperate with ATBF1 in AFP transcription
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Framework in TGF-β Family Signaling”
- Place of Presentation
  大和屋本店（松山市）
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] TGF-β/Smadシグナル伝達系と転写因子ATBF1によるα-fetoprotein遺伝子転写抑制
- Author(s)
  坂田宣夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-25670168

1. ITOH Susumu (70223154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. SASAHARA Masakiyo (20154015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 川口誠 (50204699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 西村理行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 伊東史子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKATA Nobuo 坂田 宣夫

Research Projects

Research Products

Co-Researchers

Smad-mediated spliceosome assembly and alternative splicingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EXPRESSION ANALYSIS OF TRANSCRIPTION FACTOR, ATBF1 AND ZFH4 IN NORMAL DEVELOPING RAT BRAINPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] TGF-β signaling cooperates with AT motif-binding factor-1 for repression of the α-fetoprotein promoter.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C18ORF1: A Novel Negative Regulator of TGF-β Signaling.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 転写因子ATBF1とTGF-βシグナル伝達系によるalpha-fetoprotein遺伝子プロモーターの協調的抑制2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] TMEPAIファミリーによるTGF-βシグナル制御機構2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Transcriptional Repression Mechanisms of TGF-β Signaling and ATBF1 on the AFP Promoter

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] TGF-β Signaling Cooperates with AT Motif Binding Factor 1 (ATBF1) to Repress α-Fetoprotein Gene in Human Hepatoma Cells.

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Negative regulation of α-fetoprotein gene transcription by TGF-β signaling with AT motif binding factor 1 (ATBF1)

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 2.TGF-β signaling cooperate with ATBF1 in AFP transcription

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] TGF-β/Smadシグナル伝達系と転写因子ATBF1によるα-fetoprotein遺伝子転写抑制

Author(s)

Organizer

Place of Presentation

Data Source

SAKATA Nobuo 坂田宣夫