Hideaki Oikawa 及川英秋

… Alternative Names

OIKAWA Hideaki 及川英秋

及川英章オピカワヒデアキ

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Researcher Number	00185175
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2021: 北海道大学, 理学研究院, 特任教授 2017: 北海道大学, 理学(系)研究科(研究院), 教授 2016 – 2017: 北海道大学, 理学研究院, 教授 2010 – 2015: Hokkaido University, 理学(系)研究科(研究院), 教授 2007 – 2012: Hokkaido University, Faculty of Scienee, Professor … More 2006: Hokkaido Univeristy, Graduate School of Science, Professor, 大学院・理学院, 教授 2006: 北海道大学, 大学院理学研究院, 教授 2003 – 2005: Hokkaido University, Division of Chemistry, Professor, 大学院・理学研究科, 教授 2001 – 2002: 北海道大学, 農学部, 助教授 1999 – 2002: 北海道大学, 大学院・農学研究科, 助教授 1993 – 1998: 北海道大学, 農学部, 助手 1988 – 1989: 北海道大学, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator Bioproduction chemistry/Bioorganic chemistry / Biomolecular chemistry / Science and Engineering / Basic Section 38040:Bioorganic chemistry-related / Bioproduction chemistry/Bioorganic chemistry / Living organism molecular science / Science and Engineering Except Principal Investigator 製造化学・食品 / Bioproduction chemistry/Bioorganic chemistry / Bioproduction chemistry/Bioorganic chemistry / Chemistry
Keywords	Principal Investigator 生合成 / 天然物 / 麹菌 / 物質生産 / ゲノム情報 / テルペン / 酸化酵素 / biosynthesis / 環化酵素 / inhibitor … More / protein phosphatase / tautomycetin / tautomycin / 阻害剤 / 糸状菌 / 化学酵素合成 / 大腸菌 / ペプチド合成酵素 / 抗腫瘍性物質 / 有機化学 / 微生物 / 酵素反応 / 生理活性 / 異種発現 / ゲノムマイニング / ゲノム編集 / 担子菌 / ペプチド / チトクロームP450 / epoxidase / cyclase / polyketides / polyethers / ポリケタイド / ポリエーテル / phytoalexins / phorbol / terpene synthases / diterpenes / ファイトアレキシン / フォルボール / ジテルペン / alternaric acid / solanapyrone / phytotoxins / pathogenic fungi / アルタナル酸 / ソラナピロン / 植物毒素 / 植物病原菌 / DNAポリメラーゼα / アフィディコリン / 抗ウイルス剤 / ト-トマイセチン / ト-トマイシン / 蛋白脱リン酸化酵素 / トートマイセチン / トートマイシン / 酸無水物 / 全生合成 / ゲノム / 抗生物質 / 二次代謝産物 / メタボローム / バイオインフォマティクス / solanapyrone A / Diels-Alder反応 … More Except Principal Investigator biosynthesis / 生合成 / AAL-toxin / Furanosylation / Choke disease / Fungitoxic compound / Epoxy fatty acid / Induced resistance / Chokol / 抗菌物質 / チョコール酸 / チョコール / 病害抵抗性機作 / チョーク / Epichloe Iyphina / チモシーがまの穂病 / スフィンゴイド / フラノシル化 / チョ-ク / Epichloe typhina / チモシ-ガマの穂病 / フラノ-ス化 / ガマの穂病 / 坑菌物質 / エポキシ脂肪酸 / 誘導性抵抗 / チョコ-ル / P450 oxygenase / cyclase / gene cluster / terpenoid / P450酸化酵素 / 環化酵素 / 遺伝子クラスター / テルペノイド / squarene / tetraterpene / biosynthetic intermediate / cyclization mechanism / terpene cyclase / diterpene / 非天然型トリテルペン / スクアレン-ホペン環化酵素 / アフィジコリンの環化機構 / テルペンテトリエン / ヤマブシタケ / 環化酵素遺伝子 / フシコクシン / テルペンテシン / アフィジコリン / サイアタジエン / エリナシン / フォマクチン / スクアレン / テトラテルペン / 生合成中間体 / 環化機構 / テルペン環化酵素 / ジテルペン / tuber inducing substance / coronatine / Diels-Alderase / tautomycin / abscisterol / altemaric acid / phytotoxin / 生体内ディールス・アルダー反応 / オッシラトキシンD / ジャスモン酸 / セパシアミドA / マクロフォミン酸 / ソラナピロン / アポトーシス / 塊茎誘導物質 / コロナチン / ディールス・アルダラーゼ / トウトマイシン / アプシステロール / アルタナル酸 / 植物毒素 Less

Exploring new biologically active metabolites using unidentified gene clusters from Basidiomycota genomesPrincipal Investigator
- Principal Investigator
  
  Hideaki Oikawa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Hokkaido University
Construction of convergent library for fungal cytochrome P450s and its application to exploring novel functionsPrincipal Investigator
- Principal Investigator
  
  Oikawa Hideaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
Development of versatile synthesis for fungal natural products by reconstitution of biosynthetic machineryPrincipal Investigator
- Principal Investigator
  
  Oikawa Hideaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
Development of a rational protocol searching novel biosynthetic gene clusters for natural product synthesisPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
Biosynthetic machinery: Deciphering and regulating the system for creating structural diversity of baioactive metabolitesPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Reconstitution of anticancer agent-biosynthetic machinery and elucidation of its mechanism on molecular diversificationPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Biosynthetic machinery: Deciphering and regulating the system for bioactive metabolite diversificationArea Organizer
- Area Organizer
  
  OIKAWA Hideaki
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Hokkaido University
Functional analysis of modular enzymes and its application to the synthesis of antitumor agentsPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
ポリペプチド合成酵素を用いた抗がん剤ライブラリーの構築Principal Investigator
- Principal Investigator
  
  及川英秋
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Studies on the Mechanism of Constructing Molecular Skeletons of Bioactive Polyether MetabolitesPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Hokkaido University
Studies on production and improvement of terpenoids using biosynthetic gene cluster in fungi and plants.
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Study on cloning of diterpene synthase genes from plantsPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Hokkaido University
Scientific research on elucidation of terpene-cyclic reactions in the biosynthesis of bioactive microbial terpenoids.
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Study of the role of phototoxins in toxin-induced symptom developmentPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
Large-scale Production of Antivirus Agent Based on Engineered BiosynthesisPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
Study on Inhibition Mechanism and Rational Design of Protein Phosphatase Inhibitor TautomycinPrincipal Investigator
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
Chemistry and New Development of Phytotoxin
- Principal Investigator
  
  ICHIHARA Akitami
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
生合成における酵素的Diels-Alder反応-----その証明と反応機構Principal Investigator
- Principal Investigator
  
  及川英秋
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Hokkaido University
Symptom and sign of infected plants--chemistry and biological activity-
- Principal Investigator
  
  YOSHIHARA Teruhiko, SAKAMURA Sadao
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  製造化学・食品
- Research Institution
  Hokkaido University

[Book] Comprehensive Natural Products Ⅲ: Chemistry and Biology,2020
- Author(s)
  Atsushi Minami, Taro Ozaki, Chengwei Liu, Hideaki Oikawa
- Total Pages
  4238
- Publisher
  Elsevier
- ISBN
  9780081026915
- Data Source
  KAKENHI-PROJECT-19H02891
[Book] Comprehensive Natural Products Ⅲ: Chemistry and Biology2020
- Author(s)
  C. Liu, A. Minami, T. Ozaki, and H. Oikawa
- Total Pages
  4238
- Publisher
  Elsevier
- ISBN
  0081026900
- Data Source
  KAKENHI-PROJECT-19H02891
[Book] 酵母菌・麹菌・乳酸菌の産業応用展開2018
- Author(s)
  及川英秋,南篤志,劉誠偉,尾﨑太郎,他69名　監修：五味勝也,阿部敬悦
- Total Pages
  264
- Publisher
  シーエムシー出版
- ISBN
  9784781313177
- Data Source
  KAKENHI-PROJECT-15H01835
[Book] Metabolite analyses of single cells2012
- Author(s)
  Akira Oikawa
- Publisher
  Plant J.
- Data Source
  KAKENHI-ORGANIZER-22108001
[Book] Plant Metabolism ana Biotechnology Hiroshi Ashihara, Alan Crozier, Atsushi Komamine2011
- Author(s)
  Yozo Okazaki, Akira Oikawa, Miyako Kusano, Fumio Matsuda, Kazuki Saito(共著)
- Publisher
  Wiley
- Data Source
  KAKENHI-ORGANIZER-22108001
[Book] "The Diels-Alderase never ending story." in Biomimetic Organic Synthesis, Vol.II2011
- Author(s)
  Minami, A., Oikawa, H.
- Publisher
  (in press)
- Data Source
  KAKENHI-PLANNED-22108002
[Book] The Diels-Alderase never ending story. Biomimetic Organic Synthesis, Vol.22011
- Author(s)
  A.Minami, H.Oikawa(共著)
- Publisher
  Wiley-VCH, New York
- Data Source
  KAKENHI-PLANNED-22108002
[Book] The Diels-Alderase never ending story2011
- Author(s)
  A.Minami, H.Oikawa(共著)
- Publisher
  Wiley-VCH, New York
- Data Source
  KAKENHI-ORGANIZER-22108001
[Book] "Diels-Alderases." in Comprehensive Natural Products Chemistry II2010
- Author(s)
  Oikawa, H.
- Total Pages
  38
- Publisher
  Elsevier.
- Data Source
  KAKENHI-PLANNED-22108002
[Book] "Chemical Defense and Toxins of Plant."in Comprehensive Natural Products Chemistry II2010
- Author(s)
  Yamane, H., Konno, K., Takabayashi, J., Sassa, T., Oikawa, H
- Total Pages
  46
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-20310126
[Book] Chemical Difence and Toxins of Plant. in Comprehensive Natural Products Chemistry II2010
- Author(s)
  Yamane, H., Konno, K., Takabayashi, J., Sassa, T., Oikawa, H.
- Total Pages
  47
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-20310126
[Book] Comprehensive Natural Products Chemistry II(Diels-Alderases)2010
- Author(s)
  Oikawa H.
- Total Pages
  39
- Data Source
  KAKENHI-PROJECT-20310126
[Book] Diels-Alderases."in Comprehensive Natural Products Chemistry II2010
- Author(s)
  Oikawa, H
- Total Pages
  39
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-20310126
[Book] "Chapter 8 Diels-Alderases," In Comprehensive Natural Products II : Chemistry and Biology ; Mander2010
- Author(s)
  Oikawa, H.
- Total Pages
  38
- Publisher
  Elsevier
- Data Source
  KAKENHI-ORGANIZER-22108001
[Book] in Comprehensive Natural Products Chemistry II(Chemical Difence and Toxins of Plant)2010
- Author(s)
  Yamane H., Konno K., Takabayashi J., Sassa T., Oikawa H., Elsevier
- Total Pages
  47
- Data Source
  KAKENHI-PROJECT-20310126
[Book] "Chapter 8 Chemical Difence and Toxins of Plant," In Comprehensive Natural Products II : Chemistry and Biology2010
- Author(s)
  H.Yamane, K.Konno, M.Sabelis, J.Takabayashi, T.Sassa, H.Oikawa(共著)
- Total Pages
  47
- Publisher
  Elsevier
- Data Source
  KAKENHI-ORGANIZER-22108001
[Book] in Comprehensive Natural Products Chemistry II(Chemical Defense and Toxins of Plant)2010
- Author(s)
  Yamane H., Konno K., Takabayashi J., Sassa T., Oikawa H., Elsevier
- Total Pages
  46
- Data Source
  KAKENHI-PROJECT-20310126
[Book] 天然物全合成の最新動向(生合成酵素による天然物の全合成抗腫瘍性物質エキノマイシンの合成を中心に)2009
- Author(s)
  渡辺賢二、大栗博毅、及川英秋
- Total Pages
  16
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-20310126
[Book] 天然物全合成の最新動向『生合成酵素による天然物の全合成抗腫瘍性物質エキノマイシンの合成を中心に』2009
- Author(s)
  渡辺賢二、大栗博毅、及川英秋
- Total Pages
  16
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-20310126
[Book] 天然物化学 -植物編- 第4章二次代謝産物の生合成 4.1節キノー、セスキー、ジテルペン (分筆担当)2007
- Author(s)
  及川, 英秋・常盤野, 哲生
- Total Pages
  10
- Publisher
  株式会社アイピーシー
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Genome-based discovery of enantiomeric pentacyclic sesterterpenes catalyzed by the fungal bifunctional terpene synthases2021
- Author(s)
  L. Jiang, X. Zhang, Y. Sato, G. Zhu, A. Minami, W. Zhang, T. Ozaki, B. Zhu, Z. Wang, X. Wang, K. Lv, J. Zhang, Y. H. Wang, S. S. Gao, C. Liu, T. Hsiang, L. Zhang, H. Oikawa, X. Liu
- Journal Title
  
  Org Lett
  
  Volume: 23 Issue: 12 Pages: 4645-4650
- DOI
  10.1021/acs.orglett.1c01361
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02891
[Journal Article] Biochemistry-guided prediction of the absolute configuration of fungal reduced polyketides2021
- Author(s)
  J. Takino, A. Kotani, T. Ozaki, W. Peng, J. Yu, Y. Guo, S. Mochizuki, K. Akimitsu, M. Hashimoto, T. Ye, A. Minami, H. Oikawa
- Journal Title
  
  Angew Chem Int Ed
  
  Volume: 60 Issue: 43 Pages: 23403-23411
- DOI
  10.1002/ange.202110658
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02891
[Journal Article] Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation of Dehydroamino Acids by UstYa Family Proteins2021
- Author(s)
  K. Sogahata, T. Ozaki, Y. Igarashi, Y. Naganuma, C. Liu, A. Minami, H. Oikawa
- Journal Title
  
  Angew Chem Int Ed
  
  Volume: 60 Issue: 49 Pages: 25729-25734
- DOI
  10.1002/ange.202111076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02891
[Journal Article] Heterologous expression of a polyketide synthase ACRTS2 in Aspergillus oryzae produces host-selective ACR toxins: coproduction of minor metabolites2021
- Author(s)
  Kotani Akari、Ozaki Taro、Takino Junya、Mochizuki Susumu、Akimitsu Kazuya、Minami Atsushi、Oikawa Hideaki
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 86 Issue: 3 Pages: 287-293
- DOI
  10.1093/bbb/zbab214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02835, KAKENHI-PROJECT-19H02891
[Journal Article] Biosynthesis of Cyclochlorotine: Identification of the Genes Involved in Oxidative Transformations and Intramolecular O,N-Transacylation2021
- Author(s)
  Jiang Yulu、Ozaki Taro、Liu Chengwei、Igarashi Yuya、Ye Ying、Tang Shoubin、Ye Tao、Maruyama Jun-ichi、Minami Atsushi、Oikawa Hideaki
- Journal Title
  
  Organic Letters
  
  Volume: 23 Issue: 7 Pages: 2616-2620
- DOI
  10.1021/acs.orglett.1c00525
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PUBLICLY-19H04635, KAKENHI-PUBLICLY-19H04644, KAKENHI-PROJECT-19H02835, KAKENHI-PROJECT-19H02891
[Journal Article] Heterologous production of fungal natural products: Reconstitution of biosynthetic gene clusters in model host <i>Aspergillus oryzae</i>2020
- Author(s)
  H. Oikawa
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 96 Issue: 9 Pages: 420-430
- DOI
  10.2183/pjab.96.031
- NAID
  130007938095
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2020-11-11
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02891
[Journal Article] Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin2020
- Author(s)
  Tetsuya Shiina, Taro Ozaki, Yusuke Matsu, Shota Nagamine, Chengwei Liu, Masaru Hashimoto, Atsushi Minami, Hideaki Oikawa
- Journal Title
  
  Organic Letters
  
  Volume: 22 Issue: 5 Pages: 1997-2001
- DOI
  10.1021/acs.orglett.0c00340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05836, KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-19H02891
[Journal Article] Reconstitution of Biosynthetic Machinery of Fungal Natural Products in Heterologous Hosts2020
- Author(s)
  Hideaki Oikawa
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 84 Issue: 3 Pages: 433-444
- DOI
  10.1080/09168451.2019.1690976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02891
[Journal Article] 糸状菌由来生物活性天然物の全生合成2020
- Author(s)
  南篤志、尾﨑太郎、及川英秋
- Journal Title
  
  ファインケミカル
  
  Volume: 49 Pages: 19-24
- Data Source
  KAKENHI-PROJECT-19H02891
[Journal Article] Total synthesis of alkaloids using both chemical and biochemical methods2020
- Author(s)
  Tanifuji Ryo、Minami Atsushi、Oguri Hiroki、Oikawa Hideaki
- Journal Title
  
  Natural Product Reports
  
  Volume: 37 Issue: 8 Pages: 1098-1121
- DOI
  10.1039/c9np00073a
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04647, KAKENHI-PROJECT-17J00931, KAKENHI-PROJECT-18K19142, KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-19H02891
[Journal Article] Predicting the chemical space of fungal polyketides by phylogeny-based bioinformatics analysis of polyketide synthase-nonribosomal peptide synthetase and its modification enzymes2020
- Author(s)
  Minami Atsushi、Ugai Takahiro、Ozaki Taro、Oikawa Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13556-13556
- DOI
  10.1038/s41598-020-70177-w
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-19H02891
[Journal Article] Fungal-derived brevianamide assembly by a stereoselective semipinacolase2020
- Author(s)
  Ye Ying、Du Lei、Zhang Xingwang、Newmister Sean A.、McCauley Morgan、Alegre-Requena Juan V.、Zhang Wei、Mu Shuai、Minami Atsushi、et al
- Journal Title
  
  Nature Catalysis
  
  Volume: 3 Issue: 6 Pages: 497-506
- DOI
  10.1038/s41929-020-0454-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-19H02891
[Journal Article] Biosynthesis of Indole Diterpene Lolitrems: Radical-Induced Cyclization of an Epoxyalcohol Affording a Characteristic Lolitremane Skeleton2020
- Author(s)
  Yulu Jiang, Taro Ozaki, Mei Harada, Tadachika Miyasaka, Hajime Sato, Kazunori Miyamoto, Junichiro Kanazawa, Chengwei Liu, Jun-ichi Maruyama, Masaatsu Adachi, Atsuo Nakazaki, Toshio Nishikawa, Masanobu Uchiyama, Atsushi Minami, Hideaki Oikawa
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 59 Issue: 41 Pages: 17996-18002
- DOI
  10.1002/anie.202007280
- NAID
  120007160289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05863, KAKENHI-PLANNED-16H06446, KAKENHI-PLANNED-17H06406, KAKENHI-PUBLICLY-19H04643, KAKENHI-PUBLICLY-19H04644, KAKENHI-PROJECT-20J01256, KAKENHI-PROJECT-18K05456, KAKENHI-PROJECT-20K15950, KAKENHI-PROJECT-19K23621, KAKENHI-PUBLICLY-20H04771, KAKENHI-PROJECT-17H06173, KAKENHI-PROJECT-19H02891
[Journal Article] Biosynthetic study of conidiation-inducing factor conidiogenone: Heterologous production and cyclization mechanism of a key bifunctional diterpene synthase2019
- Author(s)
  Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 83 Issue: 2 Pages: 192-201
- DOI
  10.1080/09168451.2018.1536518
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PUBLICLY-17H05425, KAKENHI-PROJECT-15H04491, KAKENHI-PROJECT-16K07724, KAKENHI-PROJECT-19H02891
[Journal Article] Efficient reconstitution of Basidiomycota diterpene erinacine gene cluster in Ascomycota host Aspergillus oryzae based on genomic DNA sequences2019
- Author(s)
  Liu, C., Minami, A., Ozaki, T., Wu, J., Kawagishi, H., Maruyama, J., Oikawa, H.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 141 Issue: 39 Pages: 15519-15523
- DOI
  10.1021/jacs.9b08935
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06402, KAKENHI-PUBLICLY-19H04644, KAKENHI-PROJECT-18K14342, KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-19H02891
[Journal Article] Ascomycota Aspergillus oryzae is an efficient expression host for production of Basidiomycota terpenes using genomic DNA sequences2019
- Author(s)
  Shota Nagamine, Chengwei Liu, Jumpei Nishishita, Takuto Kozaki, Kaho Sogahata, Yoshiro Sato, Atsushi Minami, Taro Ozaki, Claudia Schmidt-Dannert, Jun-ichi Maruyama, Hideaki Oikawa
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 85 Issue: 15
- DOI
  10.1128/aem.00409-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04644, KAKENHI-PROJECT-18K14342, KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-19H02891
[Journal Article] Total Biosynthesis of Antiangiogenic Agent (-)-Terpestacin by Artificial Reconstitution of the Biosynthetic Machinery in Aspergillus oryzae2018
- Author(s)
  Narita Koji、Minami Atsushi、Ozaki Taro、Liu Chengwei、Kodama Motoichiro、Oikawa Hideaki
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 83 Issue: 13 Pages: 7042-7048
- DOI
  10.1021/acs.joc.7b03220
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-16H03277, KAKENHI-PROJECT-17K07666
[Journal Article] Theoretical Study of Sesterfisherol Biosynthesis: Computational Prediction of Key Amino Acid Residue in Terpene Synthase2018
- Author(s)
  Sato Hajime、Narita Koji、Minami Atsushi、Yamazaki Mami、Wang Chao、Suemune Hironori、Nagano Shingo、Tomita Takeo、Oikawa Hideaki、Uchiyama Masanobu
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2473-2473
- DOI
  10.1038/s41598-018-20916-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PUBLICLY-17H05430, KAKENHI-PROJECT-17H06173, KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-16H03277, KAKENHI-PROJECT-18K06544
[Journal Article] Enzymatic formation of a skipped methyl-substituted octaprenyl side chain of longestin (KS-505a): Involvement of homo-IPP as a common extender unit2018
- Author(s)
  Ozaki Taro、Shinde Sandip S.、Gao Lei、Okuizumi Ryo、Liu Chengwei、Ogasawara Yasushi、Lei Xiaoguang、Dairi Tohru、Minami Atsushi、Oikawa Hideaki
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 22 Pages: 6629-6632
- DOI
  10.1002/anie.201802116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835, KAKENHI-PLANNED-16H06452, KAKENHI-PUBLICLY-17H05425
[Journal Article] Identification of novel sesterterpenes by genome mining of phytopathogenic fungi Phoma and Colletotrichum sp.2018
- Author(s)
  Gao Lei、Narita Koji、Ozaki Taro、Kumakura Naoyoshi、Gan Pamela、Minami Atsushi、Liu Chengwei、Lei Xiaoguang、Shirasu Ken、Oikawa Hideaki
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 59 Issue: 12 Pages: 1136-1139
- DOI
  10.1016/j.tetlet.2018.02.022
- NAID
  120006814278
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835, KAKENHI-PUBLICLY-17H05425, KAKENHI-PROJECT-17H06172
[Journal Article] Subcellular localization of aphidicolin biosynthetic enzymes heterologously expressed in Aspergillus oryzae2018
- Author(s)
  A. Ban, M. Tanaka, R. Fujii, A. Minami, H. Oikawa, T. Shintani, K. Gomi
- Journal Title
  
  Bioscience Biotechnology and Biochemistry
  
  Volume: 82 Issue: 1 Pages: 139-147
- DOI
  10.1080/09168451.2017.1399789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Stepwise cyclopropanation on the polycyclopropanated polyketide formation in jawsamycin biosynthesis2017
- Author(s)
  Hiratsuka, T.; Suzuki, H.; Minami, A.; Oikawa, H.
- Journal Title
  
  Organic and Biomolecular Chemistry
  
  Volume: 15 Issue: 5 Pages: 1076-1079
- DOI
  10.1039/c6ob02675c
- NAID
  120006383812
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835
[Journal Article] Focused genome mining of structurally related sesterterpenes: enzymatic formation of enantiomeric and diastereomeric products2017
- Author(s)
  Narita, K., Sato, H., Minami, A., Kudo, K., Gao, L., Liu, C., Ozaki, T., Kodama, M.., Lei, X., Taniguchi, T., Monde, K., Yamazaki, M., Uchiyama, M., Oikawa, H.
- Journal Title
  
  Organic letters
  
  Volume: 19 Issue: 24 Pages: 6696-6699
- DOI
  10.1021/acs.orglett.7b03418
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07666, KAKENHI-PLANNED-16H06446, KAKENHI-PLANNED-16H06454, KAKENHI-PUBLICLY-17H05430, KAKENHI-PROJECT-17H06173, KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-15H03111, KAKENHI-PROJECT-16H03277
[Journal Article] Biosynthetic Machinery of Diterpene Pleuromutilin Isolated from Basidiomycete Fungi2017
- Author(s)
  Yamane Momoka、Minami Atsushi、Liu Chengwei、Ozaki Taro、Takeuchi Ichiro、Tsukagoshi Tae、Tokiwano Tetsuo、Gomi Katsuya、Oikawa Hideaki
- Journal Title
  
  ChemBioChem
  
  Volume: 18 Issue: 23 Pages: 2317-2322
- DOI
  10.1002/cbic.201700434
- NAID
  120006541883
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835
[Journal Article] Reconstitution of biosynthetic machinery of fungal polyketides: unexpected oxidations of biosynthetic intermediates by expression host2016
- Author(s)
  R. Fujii, T. Ugai, H. Ichinose, M. Hatakeyama, T. Kosaki, K. Gomi, I. Fujii, A. Minami, and H. Oikawa
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 80 Issue: 3 Pages: 426-431
- DOI
  10.1080/09168451.2015.1104234
- NAID
  120005981344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Genome mining approach for harnessing the cryptic gene cluster in Alternaria solani: production of PKS-NRPS hybrid metabolite, didymellamide B.2016
- Author(s)
  T. Ugai, A. Minami, K. Gomi, H. Oikawa
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 57 Issue: 25 Pages: 2793-2796
- DOI
  10.1016/j.tetlet.2016.05.043
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Catalytic asymmetric synthesis of the common amino acid component in the biosynthesis of tetrahydroisoquinoline alkaloids.2016
- Author(s)
  R. Tanifuji, H. Oguri, K. Koketsu, Y. Yoshinaga, A. Minami, H. Oikawa
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 57 Issue: 5 Pages: 623-626
- DOI
  10.1016/j.tetlet.2015.12.110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Biosynthesis of shearinine: Diversification of a tandem prenyl moiety of fungal indole diterpenes2016
- Author(s)
  Liu, C.; Minami, A.; Dairi, T.; Gomi, K.; Scott, B.; Oikawa, H.
- Journal Title
  
  Organic Letters
  
  Volume: 18 Issue: 19 Pages: 5026-5029
- DOI
  10.1021/acs.orglett.6b02482
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-16K16636
[Journal Article] Total Biosynthesis of Fungal Indole Diterpenes Using Cell Factories.2016
- Author(s)
  A. Minami, C. W. Liu, H. Oikawa
- Journal Title
  
  Heterocycles
  
  Volume: 92 Issue: 3 Pages: 397-421
- DOI
  10.3987/rev-15-830
- NAID
  40020766375
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Recent advances of Diels-Alderases involved in natural product biosynthesis.2016
- Author(s)
  A. Minami, H. Oikawa
- Journal Title
  
  Journal of Antibiotics
  
  Volume: 69 Issue: 7 Pages: 500-506
- DOI
  10.1038/ja.2016.67
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Unveiling the Biosynthetic Pathway of the Ribosomally Synthesized and Post-translationally Modified Peptide Ustiloxin B in Filamentous Fungi.2016
- Author(s)
  Y. Ye, A. Minami, Y. Igarashi, M. Izumikawa, M. Umemura, N. Nagano, M. Machida, T. Kawahara, K. Shin-ya, K. Gomi, H. Oikawa
- Journal Title
  
  Angewandte Chemie-International Edition
  
  Volume: 55 Issue: 28 Pages: 8072-8075
- DOI
  10.1002/anie.201602611
- NAID
  120006318732
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-26505015
[Journal Article] Multiple oxidative modifications in the ophiobolin biosynthesis: P450 oxidations found in the genome mining2016
- Author(s)
  K. Narita, R. Chiba, A. Minami, M. Kodama, I. Fujii, K. Gomi and H. Oikawa
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Issue: 9 Pages: 1980-1983
- DOI
  10.1021/acs.orglett.6b00552
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12737, KAKENHI-PROJECT-15H01835
[Journal Article] Reconstitution of biosynthetic machinery for highly elaborated indole diterpene penitrem2015
- Author(s)
  C. W. Liu, K. Tagami, A. Minami, T. Matsumoto, J. C. Frisvad, H. Suzuki, J. Ishikawa, K. Gomi, and H. Oikawa
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 54
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis2015
- Author(s)
  T. Ugai, A. Minami, R. Fujii, M. Tanaka, K. Gomi, H. Oikawa
- Journal Title
  
  Chem. Commun
  
  Volume: 51 Issue: 10 Pages: 1878-1878
- DOI
  10.1039/c4cc09512j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-22108007, KAKENHI-PROJECT-15H01835
[Journal Article] Reconstitution of biosynthetic machinery for the synthesis of the highly elaborated indole diterpene Penitrem.2015
- Author(s)
  Liu, C., Tagami, K., Minami, A., Matsumoto, T., Frisvad, J.C., Suzuki, H., Ishikawa, J., Gomi, K., and Oikawa, H.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 54 Issue: 19 Pages: 5748-5752
- DOI
  10.1002/anie.201501072
- NAID
  130007492191
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108007, KAKENHI-PLANNED-22108010, KAKENHI-PUBLICLY-25108727, KAKENHI-PROJECT-15H01835
[Journal Article] Genome Mining for Sesterterpenes Using Bifunctional Terpene Synthases Reveals a Unified Intermediate of Di/Sesterterpenes2015
- Author(s)
  Y. Ye, A. Minami, A. Mandi, C. Liu, T. Taniguchi, T. Kuzuyama, K. Monde, K. Gomi, and H. Oikawa
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 137 Issue: 36 Pages: 11846-11853
- DOI
  10.1021/jacs.5b08319
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-15H03111, KAKENHI-PROJECT-26292058
[Journal Article] Minimum Information About a Biosynthetic Gene Cluster2015
- Author(s)
  M. H. Medema, H. Oikawa　他
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 11 Issue: 9 Pages: 625-631
- DOI
  10.1038/nchembio.1890
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835, KAKENHI-PROJECT-26292058
[Journal Article] Biosynthetic Study on Antihypercholesterolemic Agent Phomoidride: General Biogenesis of Fungal Dimeric Anhydrides2015
- Author(s)
  R. Fujii, Y. Matsu, A. Minami, S. Nagamine, I. Takeuchi, K. Gomi, and H. Oikawa
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Issue: 22 Pages: 5658-5661
- DOI
  10.1021/acs.orglett.5b02934
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01835
[Journal Article] Reconstitution of biosynthetic machinery for highly elaborated indole diterpene penitrem2015
- Author(s)
  C. W. Liu, K. Tagami, A. Minami, T. Matsumoto, J. C. Frisvad, H. Suzuki, J. Ishikawa, K. Gomi, and H. Oikawa
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 2015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22108001
[Journal Article] Biogenetically inspired synthesis and skeletal diversification of indole alkaloids2014
- Author(s)
  H. Mizoguchi, H. Oikawa, H. Oguri
- Journal Title
  
  Nat. Chem.
  
  Volume: 6 Issue: 1 Pages: 57-64
- DOI
  10.1038/nchem.1798
- NAID
  120005476195
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PROJECT-23310156
[Journal Article] Rapid reconstitution of biosynthetic machinery for fungal metabolites in Aspergillus oryzae: Total biosynthesis of aflatrem2014
- Author(s)
  K. Tagami, A. Minami, R. Fujii, C. W. Liu, K. Gomi, T. Dairi, H. Oikawa
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 14 Pages: 2076-2076
- DOI
  10.1002/cbic.201402195
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-22108007, KAKENHI-PLANNED-23108101
[Journal Article] Synthesis of Natural Products with Biosynthetic Machinery2014
- Author(s)
  南篤志、及川英秋
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 72 Issue: 5 Pages: 548-556
- DOI
  10.5059/yukigoseikyokaishi.72.548
- NAID
  130004548605
- ISSN
  0037-9980, 1883-6526
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Analysis of enantiofacial selective epoxidation catalyzed by flavin-containing monooxygenase Lsd18 involved in ionophore polyether lasalocid biosynthesis2014
- Author(s)
  G. Suzuki, A. Minami, M. Shimaya, T. Kodama, Y. Morimoto, H. Oguri, H. Oikawa
- Journal Title
  
  Chem. Lett.
  
  Volume: 43 Issue: 11 Pages: 1779-1779
- DOI
  10.1246/cl.140721
- NAID
  130004677603
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PROJECT-26750361
[Journal Article] Biosynthesis of the structurally unique polycyclopropanated polyketide-nucleoside hybrid jawsamycin (FR-900848)2014
- Author(s)
  T. Hiratsuka, H. Suzuki, R. Kariya, T. Seo, A. Minami, H. Oikawa
- Journal Title
  
  Angew. Chem. Int. Edit.
  
  Volume: 53 Issue: 42 Pages: 1-4
- DOI
  10.1002/anie.201204109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Allosteric Regulation of Epoxide Opening Cascades by a Pair of Epoxide Hydrolases in Monensin Biosynthesis,2014
- Author(s)
  A. Minami, T. Ose, K. Sato, A. Oikawa, K. Kuroki, K.Maenaka, H.Oguri and H. Oikawa
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 9 Issue: 2 Pages: 562-569
- DOI
  10.1021/cb4006485
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108002
[Journal Article] Core Assembly Mechanism of Quinocarcin/Sf-1739: Bimodular Complex Nonribosomal Peptide Synthetases for Sequential Mannich-Type Reactions2013
- Author(s)
  T. Hiratsuka, K. Koketsu, A. Minami, S. Kaneko, C. Yamazaki, K. Watanabe, H. Oguri, and H. Oikawa
- Journal Title
  
  Chem. Biol.
  
  Volume: 20 Issue: 12 Pages: 1523-1535
- DOI
  10.1016/j.chembiol.2013.10.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108002, KAKENHI-PROJECT-25514004
[Journal Article] Regiospecificities and prenylation mode specificities of the fungal indole diterpene prenyltransferases AtmD and PaxD2013
- Author(s)
  C. Liu, M. Noike, A. Minami, H. Oikawa, T. Dairi
- Journal Title
  
  Appl. Environ. Microbiol.
  
  Volume: 79 Issue: 23 Pages: 7298-7304
- DOI
  10.1128/aem.02496-13
- NAID
  120005451569
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-23108101
[Journal Article] Pictet-Spenglerase Involved in Tetrahydroisoquinoline Antibiotic Biosynthesis2012
- Author(s)
  K.Koketsu, A.Minami, K.Watanabe, H.Oguri, H.Oikawa
- Journal Title
  
  Curr.Opin.Chem.Biol.
  
  Volume: Vol.15(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Enzymatic Catalysis of Anti-Baldwin Ring-Closure in Polyether Biosynthesis2012
- Author(s)
  K.Hotta, X.Chen, R.S.Paton, A.Minami, H.Li, K.Swamina-than, I.Mathews, K.Watanabe, H.Oikawa, K.N.Houk, K.C.-Y.
- Journal Title
  
  Nature
  
  Volume: 483 No.7389 Pages: 355-358
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Enzymatic Catalysis of Anti-Baldwin Ring-Closure in Polyether Biosynthesis2012
- Author(s)
  K.Hotta, X.Chen, R.S.Paton, A.Minami, H.Li, K.Swamina-than, I.Mathews, K.Watanabe, H.Oikawa, K.N.Houk, K.C.-Y.
- Journal Title
  
  Nature
  
  Volume: 483 No.7389 Pages: 355-358
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001
[Journal Article] The Pictet-Spengler Mechanism Involved in the Biosynthesis of Tetrahydroisoquinoline Antitumor Antibiotics : A Novel Function for a Nonribosomal Peptide Synthetase2012
- Author(s)
  K.Koketsu, A.Minami, K.Watanabe, H.Oguri, H.Oikawa
- Journal Title
  
  Methods Enzymol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Crystallization and Preliminary X-ray Crystallographic Study of a Methyltransferase involved in 2-Methylisoborneol (2-MIB) Biosynthesis in Streptomyces lasaliensis2011
- Author(s)
  O.Ariyawutthiphan, T.Ose, M.Tsuda, Y.-G.Gao, M.Yao, A.Minami, H.Oikawa, I.Tanaka
- Journal Title
  
  Acta Crystallogr.Sect F Struct.Biol.Cryst.Commun.
  
  Volume: Vol.67 Issue: 3 Pages: 417-420
- DOI
  10.1107/s1744309110051523
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Involvement of Common Intermediate 3-Hydroxy-L-Kynurenine in Chromophore Biosynthesis of Quinomycin Family Antibiotics.2011
- Author(s)
  Y.Hirose, K.Watanabe, A.Minami, T.Nakamura, H.Oguri, H.Oikawa
- Journal Title
  
  J.Antibiot
  
  Volume: Vol.64, No.1 Pages: 117-122
- NAID
  10030637815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase .ALPHA.: Heterologous Expression of Four Biosynthetic Genes in Aspergillus oryzae2011
- Author(s)
  R.Fujii, A.Minami, T.Tsukagoshi, N.Sato, T.Sahara, S.Ohgiya, K.Gomi, H.Oikawa
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 75 Issue: 9 Pages: 1813-1817
- DOI
  10.1271/bbb.110366
- NAID
  10029757547
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-22108007
[Journal Article] Generation of Anti-trypanosomal Agents through Concise Synthesis and structural Diversification of Sesquiterpene Analogues2011
- Author(s)
  H.Oguri, T.Hiruma, Y.Yamagishi, H.Oikawa, A.Ishiyama, K.Otoguro, H.Yamada, S.Omura
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: Vol.133, No 18 Issue: 18 Pages: 7096-7105
- DOI
  10.1021/ja200374q
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Involvement of Common Intermediate 3-Hydroxy-L-Kynurenine in Chromophore Biosynthesis of Quinomycin Family Antibiotics.2011
- Author(s)
  Y.Hirose, K.Watanabe, A.Minami, T.Nakamura, H.Oguri, H.Oikawa
- Journal Title
  
  J.Antibiot Vol.64, No.1
  
  Pages: 117-122
- NAID
  10030637815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] 生合成マシナリーを用いた抗腫瘍性物質生産の試み2011
- Author(s)
  渡辺賢二、大栗博毅、及川英秋
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 69巻、No.1 Pages: 26-30
- NAID
  10027617152
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Enzymatic Epoxide-Opening Cascades Catalyzed by a Pair of Epoxide Hydrolases in the Ionophore Polyether Biosynthesis.2011
- Author(s)
  A.Minami, A.Migita, D.Inada, K.Hotta, K.Watanabe, H.Oguri, H.Oikawa
- Journal Title
  
  Org Lett
  
  Volume: Vol.13, No.7 Pages: 1638-1641
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Remarkable synergistic effect between MonBI and MonBII on epoxide opening reaction in ionophore polyether monensin biosynthesis2011
- Author(s)
  K.Sato, A.Minami, T.Ose, H.Oguri, H.Oikawa
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: Vol.52, No.41 Pages: 5277-5280
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Involvement of Common Intermediate L-3-Hydroxyknyurenine in the Chromophore Biosynthesis of Quinomycin Family Antibiotics2011
- Author(s)
  Y.Hirose, K.Watanabe, A.Minami, T.Nakamura, H.Oguri, H.Oikawa
- Journal Title
  
  J.Antibiot.
  
  Volume: Vol.64, No.1 Issue: 1 Pages: 117-122
- DOI
  10.1038/ja.2010.142
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Enzymatic Epoxide-opening Cascades Catalyzed by a Pair of Epoxide Hydrolases in the Ionophore Polyether Biosynthesis2011
- Author(s)
  A.Minami, A.Migita, D.Inada, K.Hotta, K.Watanabe, H.Oguri, H.Oikawa
- Journal Title
  
  Org.Lett.
  
  Volume: Vol.13, No.7 Pages: 7096-7105
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Reconstruction of the Saframycin Core Scaffold Defines Dual Pictet-Spengler Mechanisms2010
- Author(s)
  K.Koketsu, K.Watanabe, H.Suda, H.Oguri, H.Oikawa
- Journal Title
  
  Nat.Chem.Biol.
  
  Volume: Vol 6, No 6 Pages: 408-410
- NAID
  120002646838
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001
[Journal Article] Solanapyrone Synthase, a Possible Diels-Alderase, and Iterative Type 1 Polyketide Synthase Encoded in a Biosynthetic Gene Cluster from Alternaria Solani.2010
- Author(s)
  K.Kasahara, T.Miyamoto, T.Fujimoto, H.Oguri, T.Tokiwano, H.Oikawa, Y.Ebizuka, I.Fujii
- Journal Title
  
  ChemBioChem
  
  Volume: vol.11, No.9 Pages: 1245-1252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.2010
- Author(s)
  Koketsu H., Watanabe K., Suda H., Oguri H., Oikawa H.
- Journal Title
  
  Nat.Chem.Biol. Vol.6
  
  Pages: 408-410
- NAID
  120002646838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Reconstruction of the Saframycin Core Scaffold Defines Dual Pictet-Spengler Mechanisms.2010
- Author(s)
  K.Koketsu, K.Watanabe, H.Suda, H.Oguri, H.Oikawa
- Journal Title
  
  Nat.Chem.Blot
  
  Volume: Vol.6, No.6 Pages: 408-410
- NAID
  120002646838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Intriguing Substrate Tolearance of Epoxide Hydrolase Lsd19 Involved in Biosynthesis of the Ionophore Antibiotic Lasalocid A.2010
- Author(s)
  Y.Matsuura, Y.Shichijo, A.Minami, A.Migita, H.Oguri, M.Watanabe, T.Tokiwano, K.Watanabe, H.Oikawa
- Journal Title
  
  Org.Lett
  
  Volume: Vol.12, No.10 Pages: 2226-2229
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Solanapyrone Synthase, a Possible Diels-Alderase, and Iterative Type I Polyketide Synthase Encoded in a Biosynthetic Gene Cluster from Alternaria Solani.2010
- Author(s)
  K.Kasahara, T.Miyamoto, T.Fujimoto, H.Oguri, T.Tokiwano, H.Oikawa, Y.Ebizuka, I.Fujii
- Journal Title
  
  ChemBioChem Vol.11, No.9
  
  Pages: 1245-1252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Reconstruction of the Saframycin Core Scaffold Defines Dual Pictet-Spengler Mechanisms.2010
- Author(s)
  K.Koketsu, K.Watanabe, H.Suda, H.Oguri, H.Oikawa
- Journal Title
  
  Nat.Chem.Biol.
  
  Volume: Vol.6, No.6 Pages: 408-410
- NAID
  120002646838
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002
[Journal Article] Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.2010
- Author(s)
  Koketsu, H., Watanabe, K., Suda, H., Oguri, H., Oikawa, H
- Journal Title
  
  Nat.Chem.Biol. (印刷中)
- NAID
  120002646838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Reconstruction of the Saframycin Core Scaffold Defines Dual Pictet-Spengler Mechanisms2010
- Author(s)
  K.Koketsu, K.Watanabe, H.Suda, H.Oguri, H. Oikawa
- Journal Title
  
  Nat.Chem.Biol Vol.6, No.6
  
  Pages: 408-410
- NAID
  120002646838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis2009
- Author(s)
  A.Migita, M.Watanabe, Y.Hirose, K.Watanabe, T.Tokiwano, H.Kinashi, H.Oikawa
- Journal Title
  
  Biosci.Biotechnol.Biochem Vol.73, No.1
  
  Pages: 169-176
- NAID
  10027536367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Biosynthetic gene-based secondary metabolite screening : a new diterpene, methyl phomopsenonate, from the fungus Phomopsis am ygdali2009
- Author(s)
  Toyomasu T., Kaneko A, Tokiwano T., Kanno Y., Kanno Y., Nuda R., Miura S., Nishioka T., Ikeda C., Mitsuhashi, W., Dairi T., Kawano T., Oikawa H., Kato N., Sassa T.
- Journal Title
  
  J.Org.Chem. Vol.74, No.1
  
  Pages: 1541-1548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway2009
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  Curr. Opinion Chem. Biol. 13(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Rationally Engineered Total Biosynthesis of a Synthetic Analogue of a Natural Quinomycin Depsipeptide in Escherichia coli.2009
- Author(s)
  Watanabe, K., (5 persons), Oikawa, H.
- Journal Title
  
  Chem Bio Chem 10
  
  Pages: 1965-1968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Rationally Engineered Total Biosynthesis of a Synthetic Analogue of a Natural Quinomycin Depsipeptide in Escherichia coli.2009
- Author(s)
  Watanabe K., (5 persons), Oikawa H.
- Journal Title
  
  ChemBioChem Vol.10
  
  Pages: 1965-1968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis2009
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  Biosci. Biotechnol. Biochem 73
  
  Pages: 169-176
- NAID
  10027536367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Biosynthetic gene-based secondary metabolite screening: a new diterpene, methyl phomopsenonate, from the fungus Phomopsis am ygdali2009
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  J. Org. Chem. 74
  
  Pages: 1541-1548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Enzymatic synthesis of molecular skeletons of complex antitumor antibiotics with non-ribosomal peptide synthetases2009
- Author(s)
  Watanabe, K., Oguri, H., Oikawa, H.
- Journal Title
  
  J.Synth.Org.Chem., Jpn. 67
  
  Pages: 1152-1160
- NAID
  10026866717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Escherichia coli Allows Efficient Modular Incorporation of Newly Isolated Quinomycin Biosynthetic Enzyme into Echinomycin Biosynthetic Pathway for Rational Design and Synthesis of Potent Antibiotic Unnatural Natural Product2009
- Author(s)
  Watanabe K., (8 persons), Oikawa, H.
- Journal Title
  
  J.Am.Chem.Soc. Vol.131
  
  Pages: 9347-9353
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway2009
- Author(s)
  Watanabe K., Oguri H., Oikawa H.
- Journal Title
  
  Curr.Opin.Chem.Biol. Vol.13
  
  Pages: 189-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Enzymatic synthesis of molecular skeletons of complex antitumor antibiotics with non-ribosomal peptide synthetases2009
- Author(s)
  Watanabe K., Oguri H., Oikawa H.
- Journal Title
  
  J.Synth.Org.Chem.Jpn. Vol.67
  
  Pages: 1152-1160
- NAID
  10026866717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway2009
- Author(s)
  Watanabe K., Oguri H., Oikawa H.
- Journal Title
  
  Curr.Opinion Chem.Biol. Vol.13, No.1
  
  Pages: 189-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway2009
- Author(s)
  Watanabe, K., Oguri, H., ^*Oikawa, H.
- Journal Title
  
  Curr.Opin.Chem.Biol. 13
  
  Pages: 189-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Escherichia coli Allows Efficient Modular Incorporation of Newly Isolated Quinomycin Biosynthetic Enzyme into Echinomycin Biosynthetic Pathway for Rational Design and Synthesis of Potent Antibiotic Unnatural Natural Product2009
- Author(s)
  Watanabe, K., (8 persons), Oikawa, H.
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 9347-9353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Unprecedented biological cyclopropanation in the biosynthesis of FR-9008482008
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  Chem. Commun.
  
  Pages: 6016-6018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Enzymatic macrolactonization in the presence of DNA leading to triostin A analogs2008
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  Chem. Biol. 15
  
  Pages: 818-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Unprecedented biological cyclopropanation in the biosynthesis of FR-9008482008
- Author(s)
  T.Tokiwano, H.Watanabe, T.Seo, H.Oikawa
- Journal Title
  
  Chem.Commun. No.1
  
  Pages: 6016-6018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Stereo-controlled synthesis of prelasalocid, a key precursor proposed in the biosynthesis of polyether antibiotic lasalocid A.2008
- Author(s)
  Hideaki Oikawa, et. al.
- Journal Title
  
  Tetrahedron Letters 49
  
  Pages: 1021-1025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Improved production of triostin A in engineered Escherichia coli with furnished quinoxaline chromophore by design of experiments in small-scale culture2008
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  Biotechnology Progress 24
  
  Pages: 134-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] 2-Methylisoborneol: Identification and functional analysis of genes controlling biosynthesis2008
- Author(s)
  Hideaki Oikawa, et. al.
- Journal Title
  
  Proc. Natl. acad. Sci. U. S. A. 105(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Stereo-controlled synthpsis of prelasalocid, a key precursor proposed in the biosynthesis of polyether antibiotic lasalocid A.2008
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Tetrahedron Letters 49
  
  Pages: 1021-1025
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Enzymatic macrolactonization in the presence of DNA leading to triostin A analogs2008
- Author(s)
  K.Koketsu, H.Oguri, K.Watanabe, Oikawa H.
- Journal Title
  
  Chem.Biol. Vol.15, No.1
  
  Pages: 818-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] 2-Methylisoborneol: Identification and functional analysis of genes controlling biosynthesis2008
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Proc. Natl. acad. Sci. U. S. A. 105(In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of Lasalocid A: Direct experimental evidence on polyene?polyepoxide hypothesis in polyether biosynthesis2008
- Author(s)
  Oikawa, H, et.al.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 12230-12231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of Lasalocid A : Direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis2008
- Author(s)
  Y.Shichijo, A.Migita, H.Oguri, M.Watanabe, T.Tokiwano, K.Watanabe, H.Oikawa
- Journal Title
  
  J.Am.Chem.Soc. Vol.130, No.1
  
  Pages: 12230-12231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] 2-Methylisoborneol: Identification and functional analysis of genes controlling biosynthesis2008
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Improved production of triostin A in engineered Escherichia coli with furnished quinoxaline chromophore by design of experiments in small-scale culture2008
- Author(s)
  A.P.Praseuth, M.B.Praseuth, H.Oguri, H.Oikawa, K.Watanabe, C.C.C.Wang
- Journal Title
  
  Biotechnology Progress Vol.24, No.1
  
  Pages: 134-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310126
[Journal Article] Stereo-controlled synthesis of prelasalocid, a key precursor proposed in the biosynthesis of polyether antibiotic lasalocid A2008
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Tetrahedron Lett. 49(6)
  
  Pages: 1021-1025
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Improved production of triostin A in engineered Escherichia coli with furnished quinoxaline chromophore by design of experiments in small-scale culture.2008
- Author(s)
  Oikawa, H., et. al.
- Journal Title
  
  Biotechnology Progress 24
  
  Pages: 134-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032004
[Journal Article] Characterization of a Rice Gene Family Encording Type-A Diterpene Cyclases2007
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Bioscience Biotechnology and Biochemistry
  
  Pages: 1701-1703
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Relative and absolute configuration of antitumor agent SW-163D.2007
- Author(s)
  Oikawa, H., et. al.
- Journal Title
  
  Biosci. Biotechnol. Biochem. 71
  
  Pages: 2969-2976
- NAID
  10027521978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032004
[Journal Article] Active site mutagenesis of the putative Diels-Alderase macrophomate synthase2007
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Chem. Commun.
  
  Pages: 1701-1703
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Active site mutagenesis of the putative Diels-Alderase macrophomate synthase2007
- Author(s)
  Hideaki Oikawa, et. al.
- Journal Title
  
  Chem. Commun.
  
  Pages: 1701-1703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Active site mutagenesis of the putative Diels-Alderase macrophomate synthase2007
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Chem. Commun. (17)
  
  Pages: 1701-1703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Relative and absolute configuration of antitumor agent SW-163D2007
- Author(s)
  Hideaki Oikawa, et. al.
- Journal Title
  
  Bioscience Biotechnology and Biochemistry 71
  
  Pages: 1701-1703
- NAID
  10027521978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Robust platform for de novo production of heterologous polyketides and nonribosomal peptides in Escherichia coli.2007
- Author(s)
  Oikawa, H., et. al.
- Journal Title
  
  Org. Biomol. Chem. 5・4
  
  Pages: 593-602
- NAID
  10018069552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032004
[Journal Article] Biosynthetic Study of FR-900848 : Unusual Observation on Polyketide Biosythesis that Did not Accept Acetate as Origin of Acetyl-CoA2006
- Author(s)
  Hideki Oikawa et al.
- Journal Title
  
  Tetrahedron Letters 46
  
  Pages: 5885-5888
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Characterization of a Rice Gene Family Encoding Type-A Diterpene Cyclases2006
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Biosci. Biotechnol. Biochem. 70(7)
  
  Pages: 1702-1710
- NAID
  10018529282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Biosynthetic Study of FR-900848 : Unusual Observation on Polyketide Biosythesis that Did not Accept Acetate as Origin of Acetul-CoA2006
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Tetrahedron Letters 46
  
  Pages: 5885-5888
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Biosynthetic Study of FR-900848 : Unsusual Observation on Polyketide Biosynthesis that Did not Accept Acetate as Origin of Acetyl-CoA2006
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Tetrahedron Lett. 47(9)
  
  Pages: 1399-1402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Characterization of a Rice Gene Family Encording Type-A Diterpene Cyclases2006
- Author(s)
  Hideaki Oikawa et al.
- Journal Title
  
  Bioscience Biotechnology and Biochemistry (in press)
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Biosynthetic Studies on the Antibiotics PF1140:A Nevel Pathway for a 2-Pyridone Framework2005
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Tetrahedron Letters 46
  
  Pages: 5885-5888
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Proposed mechanism for diterpene synthases in the formation of phomactatriene and taxadiene2005
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Org. Biomol. Chem. 3(15)
  
  Pages: 2713-2722
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Involvement of the Diels-Alderases in the biosynthesis of natural products2005
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Bull. Chem. Soc. Jpn. 78(4)
  
  Pages: 537-554
- NAID
  10015462879
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Biosynthetic Studies on the Antibiotics PF1140: A Novel Pathway for a 2-Pyridone Framework2005
- Author(s)
  Hideaki Oikawa et al.
- Journal Title
  
  Tetrahedron Letters 46(35)
  
  Pages: 5885-5888
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] The Relative and Absolute Configuration of PF11402005
- Author(s)
  Hideaki Oikawa et al.
- Journal Title
  
  The Journal of Antibiotics 58(6)
  
  Pages: 425-427
- NAID
  10016458154
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] The Relative and Absolute Configuration of PF11402005
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  The Journal of Antibiotics 58
  
  Pages: 425-427
- NAID
  10016458154
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Proposed mechanism for diterpene synthases in the formation of Phomactatriene and taxadiene2005
- Author(s)
  Hideaki, Oikawa, et. al.
- Journal Title
  
  Organic and Biomolecular Chemistry 3
  
  Pages: 2713-2722
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Involvement of the Diels-Alderases in the biosynthesis of natural products2005
- Author(s)
  Hideaki Oikawa et al.
- Journal Title
  
  Bulletin of the Chemical Society of Japan 78(4)
  
  Pages: 537-554
- NAID
  10015462879
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Proposed mechanism for diterpene synthases in the formation of Phomactatriene and taxadiene2005
- Author(s)
  Hideaki Oikawa et al.
- Journal Title
  
  Organic and Biomolecular Chemistry 3(15)
  
  Pages: 2713-2722
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Involvernent of the Diels-Alderases in the biosynthesis of natural products2005
- Author(s)
  Hideaki, Oikawa
- Journal Title
  
  Bulletin of the Chemical Society of Japan 78
  
  Pages: 537-554
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Biosynthetic Studies on the Antibiotics PF1140: A Novel Pathway for a 2-Pyridone Framework2005
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  Tetrahedron Lett. 46(35)
  
  Pages: 5885-5888
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] The Relative and Absolute Configuration of PF11402005
- Author(s)
  H. Oikawa, et al.
- Journal Title
  
  J. Antibiot. 58(6)
  
  Pages: 425-427
- NAID
  10016458154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Journal Article] Enzymatic catalysis of the Diels-Alder reaction in the biosynthesis of natural products2004
- Author(s)
  H.Oikawa, T.Tokiwano
- Journal Title
  
  Nat.Prod.Rep. 21
  
  Pages: 321-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14360061
[Journal Article] Enzymatic catalysis of the Diels-Alder reaction in the biosynthesis of natural products2004
- Author(s)
  H.Oikawa et al.
- Journal Title
  
  Nat.Prod.Rep. 21(3)
  
  Pages: 321-352
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14360061
[Presentation] ゲノム情報を利用した生物活性天然物の酵素合成戦略およびその応用展開2022
- Author(s)
  及川英秋
- Organizer
  日本農芸化学会2022年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 酵素を用いた天然物合成の新展開2021
- Author(s)
  及川英秋
- Organizer
  第32回万有仙台シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 複雑な天然物の酵素合成における質量分析2021
- Author(s)
  及川英秋
- Organizer
  第69回質量分析総合討論会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 酵素を駆使した天然物合成を目指して2021
- Author(s)
  及川英秋
- Organizer
  第47回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 酵素合成による天然物供給法の開発は応用研究につながるか2021
- Author(s)
  及川英秋
- Organizer
  日本ケミカルバイオロジー学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 複雑で驚異的生物活性を持つ天然物の酵素合成を夢見て2021
- Author(s)
  及川英秋
- Organizer
  日本農芸化学会北海道支部第2回支部講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] Total biosynthetic study of bioactive fungal natural products: Pathway elucidation and genome mining2021
- Author(s)
  Hideaki Oikawa
- Organizer
  Pacifichem2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 糸状菌天然物の網羅的生産法の開発への挑戦：きのこ由来天然物も合成可能か？2020
- Author(s)
  及川英秋
- Organizer
  高分子学会北海道支部
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 生合成マシナリーの再構築を用いた生物活性天然物の生合成研究2019
- Author(s)
  及川英秋
- Organizer
  2019 年度(第 34 回)日本放線菌学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] Efficient and versatile total biosynthesis of mushroom bioactive terpenoids2019
- Author(s)
  Hideaki Oikawa
- Organizer
  The Third A3 Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 生合成酵素を用いた生理活性天然物の生産2019
- Author(s)
  及川英秋
- Organizer
  日本農芸化学会北海道支部第２回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] Biosynthetic Study and Genome Mining of Fungal Terpenoids2019
- Author(s)
  Hideaki Oikawa
- Organizer
  TERPNET2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] 生合成マシナリー再構築による生理活性物質の生産と多様性創出機構の解明2019
- Author(s)
  及川英秋
- Organizer
  日本農芸化学会東北支部第 154 回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02891
[Presentation] Biosynthetic mechanism of fungal ribosomal peptides RiPPS2018
- Author(s)
  Taro Ozaki, Chengwei Liu, Atsushi Minami, Hideaki Oikawa
- Organizer
  農芸化学会2018年度大会シンポジウム“多様なペプチド化合物を創出する微生物が備えた生合成戦略”
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Nature’s strategy for synthesis of biologically active small molecule2018
- Author(s)
  Hideaki Oikawa
- Organizer
  Students Seminar of NIMS Joint Graduate Program
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] ゲノム情報を用いた有用生物活性を持つ低分子化合物の汎用的酵素合成法の開発2017
- Author(s)
  及川　英秋
- Organizer
  北大－ＮＩＭＳジョイントシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Total biosynthetic study of fungal metabolites2017
- Author(s)
  Hideaki Oikawa
- Organizer
  9th US-Japan Seminar on the Biosynthesis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 生物が選択した天然物合成戦略：糸状菌天然物を中心に2017
- Author(s)
  及川英秋
- Organizer
  日本化学会第97春季年会特別企画新領域研究グループシンポジウム
- Place of Presentation
  慶應義塾大学（神奈川県・横浜市）
- Year and Date
  2017-03-16
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 抗生物質プロイロムチリンの生合成研究 (3)2017
- Author(s)
  山根桃華,南篤志,劉成偉,尾崎太郎,塚越多映,常盤野哲生,五味勝也,及川英秋
- Organizer
  日本化学会第97春季年会 2017
- Place of Presentation
  慶應義塾大学　日吉キャンパス（神奈川県・横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K12737
[Presentation] Construction of focused library of structurally related fungal metabolites2017
- Author(s)
  Atsushi Minami, Chengwei Liu, Taro Ozaki, Hideaki Oikawa
- Organizer
  The Second A3 Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Construction of Focused Library of Structurally Related Fungal Metabolites Using Genome Mining2017
- Author(s)
  及川　英秋
- Organizer
  1st China-Japan Joint Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 骨格構造が類似した天然物の集中的生合成法の開発2017
- Author(s)
  及川　英秋
- Organizer
  日本ケミカルバイオロジー学会第12回年会特別講演“有機合成化学を起点とするものづくり戦略”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 生合成マシナリー再構築による天然物合成の新展開2017
- Author(s)
  及川　英秋
- Organizer
  東京農工大学大学院特別講演会
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 麹菌異種発現系を用いたAbscisic Acidの生合成研究（3）2017
- Author(s)
  小崎拓登,南篤志,五味勝也,及川英秋
- Organizer
  日本農芸化学会大会2017
- Place of Presentation
  京都女子大学（京都府・東山区）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K12737
[Presentation] Total Biosynthesis of Microbial Natural Products2016
- Author(s)
  H. Oikawa
- Organizer
  The 8th Takeda Science Foundation Symposium
- Place of Presentation
  Center for Learning and Innovation (Suita, Osaka)
- Year and Date
  2016-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Recent Topics for Total Biosynthesis of Fungal Natural Products2016
- Author(s)
  Hideaki Oikawa
- Organizer
  Peking University & Hokkaido University Joint Seminar on Organic Chemistry and Chemical Biology
- Place of Presentation
  Peking University, Beijing, China
- Year and Date
  2016-05-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 天然物生合成マシナリーから生合成リデザインへ：麹菌による驚異的異種発現2016
- Author(s)
  及川英秋
- Organizer
  生物合成系の再設計による複雑骨格機能分子の革新的創成科学　新学術領域「生合成リデザイン」キックオフシンポジウム
- Place of Presentation
  東京大学薬学系総合研究棟(東京都・文京区）
- Year and Date
  2016-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Genome mining of sesterterpenes by bifunctional terpene synthase: Unified biogenesis of sesterterpenes2015
- Author(s)
  Ying Ye, Atsushi Minami, Katsuya Gomi, Hideaki Oikawa
- Organizer
  第25回イソプレノイド研究会
- Place of Presentation
  東北大学片平さくらホール（宮城県・仙台市）
- Year and Date
  2015-09-14
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Total biosynthetic study of antitumor antibiotic ophiobolins using by Aspergillus oryzae heterologous expression system2015
- Author(s)
  Koji Narita , Ryota Chiba , Atsushi Minami , Hideaki Oikawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii (USA)
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12737
[Presentation] 糸状菌発現系を利用した、糸状菌酸無水物二量体型天然物の生合成研究2015
- Author(s)
  藤居瑠彌、南　篤志、五味　勝也、及川　英秋
- Organizer
  日本化学会
- Place of Presentation
  日本大学理工学部船橋キャンパス／薬学部（千葉県船橋市）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25560398
[Presentation] Reconstitution of biosynthetic machinery for highly elaborated indole diterpene penitrem in Aspergillus oryzea2015
- Author(s)
  Liu Chengwei , Koichi Tagami , Atsushi Minami , Tomoyuki Matsumoto , Hideaki Oikawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Total biosynthetic study of bioactive fungal natural products: Pathway elucidation and genome mining2015
- Author(s)
  H. Oikawa
- Organizer
  Biosynthesis of Natural Products, Pacifichem2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Study on the enzymatic construction of polycyclopropane skeleton in jawsamycin biosynthesis2015
- Author(s)
  Atsushi Minami , Tomoshige Hiratsuka , Hideaki Oikawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 生合成マシナリー再構築法による糸状菌天然物の全生合成2015
- Author(s)
  及川英秋
- Organizer
  天然有機化合物の生合成研究―新潟ミニシンポジウム―
- Place of Presentation
  トキメイト（新潟県、新潟市）
- Year and Date
  2015-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] Novel enzymatic reaction mechanism found in biosynthesis of natural products2015
- Author(s)
  H. Oikawa
- Organizer
  Bioorganic Reaction Mechanisms, Pacifichem2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 麹菌異種発現系を利用したペニトレム生合成マシナリーの解明2015
- Author(s)
  南　篤志、劉　成偉、田上　紘一、松本　知之、Jens Christian Frisvad, 鈴木　秀幸、石川　淳、五味　勝也、及川　英秋
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  神奈川県民ホール（神奈川県・横浜市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H01835
[Presentation] 麹菌発現系を利用した抗腫瘍性物質ophiobolin類の全生合成研究2015
- Author(s)
  成田　興司、千葉　諒太、南　篤志、藤井　勲、及川　英秋
- Organizer
  日本化学会北海道支部　2015年夏季研究発表会
- Place of Presentation
  北海道教育大学函館校（北海道・函館市）
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-15K12737
[Presentation] ゲノム情報を利用した微生物代謝産物生産法の開発2014
- Author(s)
  及川　英秋
- Organizer
  日本生物工学会大会シンポジウム
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌）
- Year and Date
  2014-09-10
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] 抗生物質Zopfiellinの生合成研究2014
- Author(s)
  松優佑・南篤志・及川英秋
- Organizer
  日本化学会春期年会
- Place of Presentation
  名古屋大学、名古屋市
- Data Source
  KAKENHI-PROJECT-25560398
[Presentation] 生合成マシナリー再構築による天然物の合成2014
- Author(s)
  及川　英秋
- Organizer
  第20回天然薬物の開発と応用シンポジウム
- Place of Presentation
  東京大学（東京・文京区）
- Year and Date
  2014-11-06
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] 微生物代謝産物の生合成機構の解明および全生合成2013
- Author(s)
  及川英秋
- Organizer
  平塚シンポジウム「ケミカルバイオロジー最前線」
- Place of Presentation
  神奈川大学湘南ひらつかキャンパス（平塚市）
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Genomic data-based synthesis of fungal natural products2013
- Author(s)
  Hideaki Oikawa
- Organizer
  International Symposium on Natural Products Chemistry and Chemical Biology 2013
- Place of Presentation
  Hotel Ohzan, Aichi-ken
- Invited
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] Nature’s way to synthesize structurally diverse small molecules2013
- Author(s)
  Hideaki Oikawa
- Organizer
  CRC symposium of post ISHHC-16
- Place of Presentation
  Hotel Millione, Hokkaido
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Functional Analysis of Prenyltransferses Responsible for Diterpene Biosynthesis in Fungi2013
- Author(s)
  C. W. Liu, M. Noike, A. Minami, H. Oikawa, and T. Dairi,
- Organizer
  11th TERPNET meeting
- Place of Presentation
  Kolymvari, Crete, Greece
- Invited
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] Nov. 24-26, 2013, Genomic data-based synthesis of fungal natural products2013
- Author(s)
  Hideaki Oikawa
- Organizer
  International Symposium on Natural Products Chemistry and Chemical Biology 2013
- Place of Presentation
  Hotel Ohzan, Aichi-ken
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Elucidation of the Catalytic Mechanism on Non-ribosomal Peptide Synthetase Involving Biosynthesis of Saframycin-Type Antitumor Agent2012
- Author(s)
  Hideaki Oikawa
- Organizer
  6th Korea-Japan Young Scientists Meeting on Bioorganic and Natural Products Chemistry
- Place of Presentation
  Seoul University(韓国)(招待講演)
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] Recent Progress on Biosynthesis of Fungal and Bacterial Metabolites2012
- Author(s)
  Hideaki Oikawa
- Organizer
  9th Asia-Pacific Marine Biotechnology Conference (APMBC2012)
- Place of Presentation
  高知市文化プラザ　かるぽーと（高知）
- Year and Date
  2012-07-13
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Organic Synthesis Learned from Nature2012
- Author(s)
  Hideaki Oikawa
- Organizer
  5th GCOE International Symposium, "Green & Sustainable Chemistry for Next Generation"
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Recent Progress on Biosynthesis of Fungal and Bacterial Metabolites2012
- Author(s)
  Hideaki Oikawa
- Organizer
  9th Asia-Pacific Marine Biotechnology Conference (APMBC2012)
- Place of Presentation
  高知市文化プラザ　かるぽーと（高知県）
- Year and Date
  2012-07-13
- Invited
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] Reaction mechanism on enzymatic polyether formation2012
- Author(s)
  Hideaki Oikawa
- Organizer
  2012 Hokkaido University Peking University Joint Symposium of Organic and Organometallic Chemistry
- Place of Presentation
  Hokkaido University(Sapporo)
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Elucidation of the Catalytic Mechanism on Non-ribosomal Peptide Synthetase Involving Biosynthesis of Saframycin-Type Antitumor Agent2012
- Author(s)
  Hideaki Oikawa
- Organizer
  6th Korea-Japan Young Scientists Meeting on Bioorganic and Natural Products Chemistry
- Place of Presentation
  Seoul University(韓国)(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Versatile Strategy on Total Biosynthesis of Fungal Natural Products2012
- Author(s)
  Hideaki Oikawa
- Organizer
  17th Malasian Chemical Congress (17MCC)
- Place of Presentation
  Putra World Trade Centre Kuala Lumpur(Malaysia)
- Year and Date
  2012-10-15
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Biosynthesis of Peptide and Polyether Antibiotics 7th US-Japan Seminar on Marine Natural Products2011
- Author(s)
  Hideaki Oikawa
- Organizer
  7th US-Japan Seminar on Marine Natural Products, Cross-Disciplinary Expansions in Marine Bioorganic Chemistry
- Place of Presentation
  沖縄コンベンションセンター(那覇市)(招待講演)
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] Recent progress on enzymatic construction of natural polyethers2011
- Author(s)
  Hideaki Oikawa
- Organizer
  IUMS 2011 Sapporo, XIII, International Congress of Bacteriology and Applied Microbiology, Bioactive Microbial Products (Biosynthesis and Activity)
- Place of Presentation
  札幌コンベンションセンター(札幌市)(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Biosynthesis of Peptide and Polyether Antibiotics 7th US-Japan Seminar on Marine Natural Products2011
- Author(s)
  Hideaki Oikawa
- Organizer
  7th US-Japan Seminar on Marine Natural Products, Cross-Disciplinary Expansions in Marine Bioorganic Chemistry
- Place of Presentation
  沖縄コンベンションセンター(那覇市)(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] 生合成マシナリー:生物活性物質構造多様性創出システムの解明と制御2011
- Author(s)
  及川英秋
- Organizer
  新学術領域研究「生合成マシナリー」第一回公開シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2011-01-08
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Recent progress on the biosynthesis of peptide antitumor antibiotics2010
- Author(s)
  Hideaki Oikawa
- Organizer
  Pacifichem 2010 Symposium on Recent Advances in Natural Products as Anticancer Agents
- Place of Presentation
  Honolulu, Hawaii, USA(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Highly unusual iterative use of NRPS involved in the biosynthesis of saframycin2010
- Author(s)
  Hideaki Oikawa
- Organizer
  Directed Biosynthesis II
- Place of Presentation
  Durham University (UK)(招待講演)
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] 抗腫瘍抗生物質サフラマイシンの生合成酵素を用いた骨格合成2010
- Author(s)
  及川英秋
- Organizer
  第52回天然有機化合物討論会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] 生合成にDiels-Alder反応は関与するのか?始まり-苦闘-結末2010
- Author(s)
  及川英秋
- Organizer
  薮田セミナー:市原メモリアルシンポジウム
- Place of Presentation
  北海道大学招待講演
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] 天然物生合成は、普遍的有用物質生産法となり得るか?2010
- Author(s)
  及川英秋
- Organizer
  化学トピックス特別講義
- Place of Presentation
  東京工業大学
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] 生合成にDiels-Alder 反応は関与するのか?2010
- Author(s)
  及川英秋
- Organizer
  始まり-苦闘-結末、薮田セミナー:市原メモリアルシンポジウム
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] Detailed Mechanism on the Enzymatic Polyether Formation2010
- Author(s)
  Hideaki Oikawa
- Organizer
  Pacifichem 2010 Symposium on Biosynthesis of Natural Products
- Place of Presentation
  Honolulu, Hawaii, USA(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] 生物活性物質の骨格合成酵素を利用した誘導体合成を目指して2010
- Author(s)
  及川英秋
- Organizer
  東京大学生物生産工学研究センターシンポジウム「微生物代謝研究におけるケミカルバイオロジーの最前線」
- Place of Presentation
  東京大学招待講演
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] Recent progress on the biosynthesis of peptide antitumor antibiotics2010
- Author(s)
  Hideaki Oikawa
- Organizer
  Pacifichem 2010 Symposium on Recent Advances in Natural Products as Anticancer Agents
- Place of Presentation
  Hilton Hawaiian Village Hotel (USA)(招待講演)
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] 生合成マシナリー:生物活性物質構造多様性創出システムの解明と制御2010
- Author(s)
  及川英秋
- Organizer
  北海道大学大学院農学研究院寄附分野講演会
- Place of Presentation
  北海道大学
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Highly unusual iterative use of NRPS involved in the biosynthesis of saframycin2010
- Author(s)
  Hideaki Oikawa
- Organizer
  Directed Biosynthesis II
- Place of Presentation
  Durham, UK(招待講演)
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] 天然物生合成は、普遍的有用物質生産法となり得るか2010
- Author(s)
  及川英秋
- Organizer
  化学科セミナー
- Place of Presentation
  東京工業大学招待講演
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] テトラヒドロイソキノリン系抗生物質SF-1739HP生合成経路の解明2009
- Author(s)
  纐纈健人、渡辺賢二、大栗博毅、及川英秋
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] Biosynthetic Engineering on Antitumor Peptide Antibiotics2009
- Author(s)
  Oikawa, H
- Organizer
  14^<th> European Congress on Biotechnology
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] Biosynthetic Engineering on Antitumor Peptide Antibiotics2009
- Author(s)
  Oikawa H.
- Organizer
  14th European Congress on Biotechnology
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] 非リボソーム依存性ペプチド合成酵素を用いた抗腫瘍性物質ライブラリー構築の試み2009
- Author(s)
  及川英秋
- Organizer
  日本化学会第89春季年会大会シンポジウム、第二次先端ウォッチングイブニングセッション「生合成工学一酵素を駆使した生物活性天然物の創製を目指して」
- Place of Presentation
  船橋
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20310126
[Presentation] Biosynthetic Studies on Polyether Antibiotics and Peptide Antitumor Agents2008
- Author(s)
  H. Oikawa
- Organizer
  The Nakanishi Symposium on Natural Products & Bioorganic Chemistry
- Place of Presentation
  Tokyo
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] 抗腫瘍性抗生物質生合成に関与する非リボソーム依存性ペプチド合成酵素を用いたケミカルバイオロジー2008
- Author(s)
  及川英秋
- Organizer
  日本農芸化学会2006年度大会シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18032004
[Presentation] ポリエーテル系抗生物質lasalocidの酵素的ポリエーテル環構築機構2008
- Author(s)
  七條, 好宏・右田, 章・大栗, 博毅・渡部, 万美・常盤野, 哲生・渡辺, 賢二・及川, 英秋
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  東京
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Biosynthetic Studies on Polyether Antibiotics and Peptide Antitumor Agents2008
- Author(s)
  H., Oikawa
- Organizer
  The Nakanishi Symposium on Natural Products and Bioorganic Chemistry 2008.
- Place of Presentation
  Tokyo
- Year and Date
  2008-05-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] 放線菌線状プラスミド上のポリケタイド生合成遺伝子クラスター2007
- Author(s)
  津田, 宗哉・右田, 章・纐纈, 健人・常盤野, 哲生・渡辺, 賢二・木梨, 陽康・池田, 治生・及川, 英秋
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  大阪
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] 推定生合成経路に基づいたポリエーテル系抗生物質イソラサロシドの全合成2007
- Author(s)
  七條, 好宏・右田, 章・渡部, 万美・大栗, 博毅・常盤野, 哲生・及川, 英秋
- Organizer
  日本化学会北海道支部2007年夏期研究発表会
- Place of Presentation
  旭川
- Year and Date
  2007-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] ポリエーテル系抗生物質ラサロシドの生合成研究 (第4報)2007
- Author(s)
  右田, 章・渡部, 万美・七條, 好宏・纐纈, 健人・廣瀬, 雄己・常盤野, 哲生・大栗, 博毅・及川, 英秋
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  大阪
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Biosynthetic Study of Polyether Antibiotic Lasalocid2006
- Author(s)
  Akira, Migita・Mami, Watanabe・Yoshihiro, Shichijo・Tetsuo, Tokiwano・Hiroki, Oguri・Hideaki, Oikawa:
- Organizer
  ICOB-5 & ISCNP-25 IUPAC International Conference on Biodiversity and Natural Products
- Place of Presentation
  Kyoto
- Year and Date
  2006-07-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Biosynthetic Studies of Two Bioactive Metabolites from Streptomyces Toward Engineered Biosynthesis2006
- Author(s)
  H., Oikawa
- Organizer
  ICOB-5 & ISCNP-25 IUPAC International Conference on Biodiversity and Natural Products
- Place of Presentation
  Kyoto
- Year and Date
  2006-07-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] ポリエーテル系抗生物質ラサロシドの生合成研究2006
- Author(s)
  右田, 章・七條, 好宏・渡部, 万美・常盤野, 哲生・大栗, 博毅・及川, 英秋
- Organizer
  日本化学会堂86春季年会
- Place of Presentation
  船橋
- Year and Date
  2006-03-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] ポリエーテル系抗生物質ラサロシドの生合成研究2006
- Author(s)
  右田, 章・大栗, 博毅・常盤野, 哲生・渡部, 万美・七條, 好宏・廣瀬, 雄己・渡辺, 賢二・木梨, 陽康・及川, 英秋
- Organizer
  第48回天然有機化合物討論会
- Place of Presentation
  仙台
- Year and Date
  2006-10-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Biosynthetic Studies of Bioactive Metabolites from Streptomyces Toward Engineered Biosynthesis2006
- Author(s)
  H., Oikawa
- Organizer
  1st International Conference on Cutting-Edge Organic Chemistry In Asia
- Place of Presentation
  Okinawa
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] ポリペプチド、ポリエーテル型天然物生合成における骨格構築機構の解析2005
- Author(s)
  及川, 英秋
- Organizer
  天然物科学研究会第二回講演会
- Place of Presentation
  東京
- Year and Date
  2005-11-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Reaction Mechanism of Enzymes Constructing Molecular Skeletons in the Biosynthesis of Natural Products2005
- Author(s)
  H. Oikawa
- Organizer
  Pacifichem2005
- Place of Presentation
  Honolulu
- Year and Date
  2005-12-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Biosynthetic Studies of Bioactive Metabolites from Streptomyces Toward Engineered Biosynthesis2005
- Author(s)
  H. Oikawa
- Organizer
  East Asian Marine Bioscience Symposium---the Frontier of Chemical Biology
- Place of Presentation
  Sapporo
- Year and Date
  2005-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208010
[Presentation] Total Biosynthesis of Bioactive Fungal Metabolites
- Author(s)
  Hideaki Oikawa
- Organizer
  24th French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  Lyon (France)
- Year and Date
  2014-09-14 – 2014-09-17
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] ゲノム情報に基づいた新規生合成経路の発見
- Author(s)
  及川英秋
- Organizer
  日本化学会第94春季年会特別企画シンポジウム”バイオインフォマティクスを駆使した生物活性天然物の供給への挑戦”
- Place of Presentation
  名古屋大学、名古屋市
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Total Biosynthesis of Fungal Indole Diterpenes
- Author(s)
  Hideaki Oikawa
- Organizer
  International Sympojium on Natural Products Chemistry and Chemical Biology 201
- Place of Presentation
  Hangzhou (China)
- Year and Date
  2014-11-22 – 2014-11-25
- Invited
- Data Source
  KAKENHI-PLANNED-22108002
[Presentation] Total Biosynthesis of Bioactive Fungal Metabolites
- Author(s)
  Hideaki Oikawa
- Organizer
  24th French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  Lyon, France
- Year and Date
  2014-09-14 – 2014-09-17
- Invited
- Data Source
  KAKENHI-ORGANIZER-22108001

1. MINAMI Atsushi (40507191)

# of Collaborated Projects: 6 results

# of Collaborated Products: 58 results
2. DAIRI Tohru (70264679)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. ISHIKAWA Jun (40202957)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. YOSHIHARA Teruhiko (90002071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SAITO Kazuki (00146705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. SAKAMURA Sadao (10001372)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. EGUCHI Tadashi (60201365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ABE Ikuro (40305496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. IKEDA Haruo (90159632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. GOMI Katsuya (60302197)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. KANAYA Shigehiko (90224584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. OGURI Hiroki (80311546)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
13. TOSHIMA Hiroaki (50237088)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SASSA Takeshi (80023456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. KATO Nobuo (50150537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. HOSHINO Tsutomu (30165542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. TOYOMASU Tomonobu (60272085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. KUZUYAMA Tomohisa (30280952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ICHIHARA Akitami (20000820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YOSHIZAWA Yuko (20269202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SATO Hiroji (20002074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. FURUICHI Naotaka (50238664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ITO Hiroyuki (10241366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YAMANE Hisakazu (80090520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TOKIWANO Tetsuo (50312343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
26. 尾崎太郎 (40709060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
27. YOSHIDA Hideaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MARUYAMA Jun-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. NAKAZAKI Atsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 河岸洋和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 児玉基一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hideaki Oikawa 及川 英秋

OIKAWA Hideaki 及川 英秋

及川 英章 オピカワ ヒデアキ

Research Projects

Research Products

Co-Researchers

Exploring new biologically active metabolites using unidentified gene clusters from Basidiomycota genomesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Construction of convergent library for fungal cytochrome P450s and its application to exploring novel functionsPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Development of versatile synthesis for fungal natural products by reconstitution of biosynthetic machineryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a rational protocol searching novel biosynthetic gene clusters for natural product synthesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biosynthetic machinery: Deciphering and regulating the system for creating structural diversity of baioactive metabolitesPrincipal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Reconstitution of anticancer agent-biosynthetic machinery and elucidation of its mechanism on molecular diversificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biosynthetic machinery: Deciphering and regulating the system for bioactive metabolite diversificationArea Organizer

Area Organizer

Project Period (FY)

Research Category

Research Institution

Functional analysis of modular enzymes and its application to the synthesis of antitumor agentsPrincipal Investigator

Principal Investigator

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Research Institution

ポリペプチド合成酵素を用いた抗がん剤ライブラリーの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the Mechanism of Constructing Molecular Skeletons of Bioactive Polyether MetabolitesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Studies on production and improvement of terpenoids using biosynthetic gene cluster in fungi and plants.

Principal Investigator

Project Period (FY)

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Study on cloning of diterpene synthase genes from plantsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Scientific research on elucidation of terpene-cyclic reactions in the biosynthesis of bioactive microbial terpenoids.

Principal Investigator

Project Period (FY)

Hideaki Oikawa 及川英秋

OIKAWA Hideaki 及川英秋

及川英章オピカワヒデアキ