MOTOKURA Toru 本倉徹

Researcher Number	00192823
Other IDs
Affiliation (Current)	2018 : 鳥取大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2007 : Tottori University, Faculty of Medicine, Associate Professor 2002 – 2006 : FACULTY OF MEDICINE, Lecturer, 医学部附属病院, 講師 2001 : 東京大学, 医学部・附属病院, 助手 2001 : Tokyo Univ., Dept. of Medicine Prof., 医学部・附属病院, 講師 1998 – 2000 : The University of Tokyo, Faculty of Medicine Branch Hospital Assistant Professor, 医学部・附属病院分院, 助手 … More
Review Section/Research Field	Principal Investigator Hematology / Hematology Except Principal Investigator Endocrinology / Hematology / Clinical nursing
Keywords	Principal Investigator サイクリン / 血液系腫瘍 / 細胞周期 / 癌遺伝子 / 造血 / 自然選択 / natural selection / p53 / p16INK4a / ARF … More Except Principal Investigator G蛋白質 / 遺伝子治療 / G蛋白質病 / 分子機構 / Jagged1 / Notch / レセプター / 巨核球 / インバースアゴニスト / Molecular Medianism / graft-versus-host disease / コンディショナルノックアウト / G PROTEIN DISEASE / HLー60細胞 / conditional knockout mouse / 自然免疫 / T細胞 / PDGF / RECEPTOR / ras / allogeneic hematopoietic stem cell transplantation / GENE THERAPY / MHC class IIプロモーター / トランスジェニックマウス / INVERSE AGONIST / 終末期 / CARDIOMEGALY / 心肥大 / アクチビン / innate immunity / マウスフレンド細胞 / 造血幹細胞 / アクチビンA / 同種造血幹細胞移植 / 移植片対宿主病 / がん化 / インターフェロンーgamma / 高カルシウム血症 / 免疫調節 / トロンボキサン / 脱感作 / GVHD / G PROTEIN / コンディショナルノックアウトマウス / G protein disease / 悪性リンパ腫 / 副甲状腺ホルモン関連ペプチド / アクチビンレセプター / MHC class II promoter / basic FGF / MOLECULAR MECHANISM / ストローマ細胞 / transgenic mouse / p53 / シランスジェニックマウス / 白血病 / HMBA(Hexamethylene Bis acetamide) / G protein / Gene therapy / TGF-β / 赤芽球 / Receptor / DESENSITIZATION / Notchシグナル / がん遺伝子 Less

Study on r-and K-selection in hematological malignanciesPrincipal Investigator
- Principal Investigator
  
  MOTOKURA Toru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tottori University
  The University of Tokyo
造血器悪性腫瘍患者・家族の終末期の実態把握と具体的支援の検討
- Principal Investigator
  
  河正子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical nursing
- Research Institution
  The University of Tokyo
Analysis of a role of r-and K-selection during malignant progression and K-induced multidrug resistancePrincipal Investigator
- Principal Investigator
  
  MOTOKURA Toru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
G PROTEIN AND DISEASES : ANALYSES OF MOLECULAR MECHANISMS AND REGULATION OF SIGNALS
- Principal Investigator
  
  IIRI Taroh
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Endocrinology
- Research Institution
  The UNIVERSITY OF TOKYO
Assessment of immune modulation by Notch signaling-exploration of immunomodulatory intervention targeting Notch system.
- Principal Investigator
  
  CHIBA Shigeru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Significance of r-and K-selection in hematological malignanciesPrincipal Investigator
- Principal Investigator
  
  MOTOKURA Toru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  THE UNIVERSITY OF TOKYO
G protein diseases : analysis and application
- Principal Investigator
  
  IIRI Taroh
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  The University of Tokyo
Analysis of cell-cycle regulation in hematopoietic cellsPrincipal Investigator
- Principal Investigator
  
  MOTOKURA Toru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  UNIVERSITY OF TOKYO
Analysis of cell-cycle regulatory mechanisms in human hematopoietic cellsPrincipal Investigator
- Principal Investigator
  
  MOTOKURA Toru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
血液系腫瘍細胞におけるPRAD1/サイクリンD1の異常発現とその作用Principal Investigator
- Principal Investigator
  
  本倉徹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
造血細胞の分化・増殖における細胞周期制御因子の発現様式の解析Principal Investigator
- Principal Investigator
  
  本倉徹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
細胞の腫瘍化に伴うホルモン遺伝子活性化のメカニズム
- Principal Investigator
  
  池田恭治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
血液系腫瘍細胞におけるPRAD1/サイクリンD1の異常発現とその作用Principal Investigator
- Principal Investigator
  
  本倉徹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
血液系腫瘍細胞における癌遺伝子D型サイクリンファミリーの発現様式の解析Principal Investigator
- Principal Investigator
  
  本倉徹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
造血細胞の増殖・分化における細胞周期制御因子サイクリンの発現Principal Investigator
- Principal Investigator
  
  本倉徹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
造血組織におけるアクチビンの作用機構の解明
- Principal Investigator
  
  内丸薫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
血液系腫瘍細胞における癌遺伝子D型サイクリンファミリーの発現様式の解析Principal Investigator
- Principal Investigator
  
  本倉徹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
アクチビンAによる白血病細胞の分化誘導機構
- Principal Investigator
  
  山下孝之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Hypercalcemic Factors in ATLPrincipal Investigator
- Principal Investigator
  
  MOTOKURA Toru
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

All 2007 2006

All Journal Article Presentation

[Journal Article] Aberrant overexpression of an epithelial marker, 14-3-3σ, in a subset of hematological malignancies2007
- Author(s)
  Motokura T, et. al.
- Journal Title
  
  BMC Cancer 7
  
  Pages : 217-217
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591042
[Journal Article] Aberrant overexpression of an epithelial marker, 14-3-3a, in a subset of hematological malignancies2007
- Author(s)
  Motokura, T., Nakamura, Y., Hiroyuki, Sato
- Journal Title
  
  BMC Cancer 7
  
  Pages : 217-217
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591042
[Journal Article] Aberrant overexpression of an epithelial marker, 14-3-3σ, in a subset of hematological malignancies2007
- Author(s)
  Toru Motokura, et. al.
- Journal Title
  
  BMC Cancer 7
  
  Pages : 217-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591042
[Journal Article] Differential 14-3-3a DNA methylation and expression in c-myc and activated H-ras-transformed cells under r and K-selection2006
- Author(s)
  Sato, H., Nakamura, Y., Motokura, T
- Journal Title
  
  Cancer Lett 236
  
  Pages : 105-114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591042
[Journal Article] Development of multidrug resistance due to multiple factors includingP-glycoprotein overexpression under K-selection after MYCand HRASoncogene activation2006
- Author(s)
  Nakamura, Y., Sato, H., Motokura, T
- Journal Title
  
  Int. J. Cancer 118(10)
  
  Pages : 2448-2454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591042
[Journal Article] 造血器腫瘍における14-3-3σ遺伝子の発現解析2006
- Author(s)
  本倉徹他
- Journal Title
  
  臨床血液 47・9
  
  Pages : 264-264
- Data Source
  KAKENHI-PROJECT-18591042
[Presentation] Analysis of 14-3-3a expression in hematological malignancies2006
- Author(s)
  Motokura, T., Sato, H
- Organizer
  The United General Meeting of the Japanese Society of Hematology and the Japanese Scoiety of Clinical Hematology
- Place of Presentation
  Fukuoka
- Year and Date
  2006-10-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591042
[Presentation] 造血器腫瘍における14-3-3σ遺伝子の発現解析2006
- Author(s)
  本倉徹、佐藤博之
- Organizer
  第68回日本血液学会・第48回日本臨床血液学会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591042

1. 内丸薫 (60251203)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
2. NAKAHARA Tatsutoshi (20110744)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. IIRI Taroh (90313022)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
4. OHNISHI Hirohide (00313023)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. FUJITA Toshiro (10114125)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. MAKITA Noriko (60353455)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. CHIBA Shigeru (60212049)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. OGAWA Seishi (60292900)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. KANDA Yoshinobu (30334379)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. SUZUKI Takahiro (40345210)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. IGARASHI Tetsuya (00134601)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. MATSUMOTO Toshio (20157374)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. WATANABE Toshiki (30182934)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 山下孝之 (10166671)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. 池田恭治 (00222878)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. 尾形悦郎 (70013761)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 河正子 (60291316)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 宮下光令 (90301142)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 高橋強志 (70332608)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. KUMANO Keiki

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. TAKAHASHI Shunji

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 芝井博四郎

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

MOTOKURA Toru 本倉 徹

Research Projects

Research Products

Co-Researchers

Study on r-and K-selection in hematological malignanciesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

造血器悪性腫瘍患者・家族の終末期の実態把握と具体的支援の検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of a role of r-and K-selection during malignant progression and K-induced multidrug resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

G PROTEIN AND DISEASES : ANALYSES OF MOLECULAR MECHANISMS AND REGULATION OF SIGNALS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment of immune modulation by Notch signaling-exploration of immunomodulatory intervention targeting Notch system.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Significance of r-and K-selection in hematological malignanciesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

G protein diseases : analysis and application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cell-cycle regulation in hematopoietic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cell-cycle regulatory mechanisms in human hematopoietic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血液系腫瘍細胞におけるPRAD1/サイクリンD1の異常発現とその作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

造血細胞の分化・増殖における細胞周期制御因子の発現様式の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

細胞の腫瘍化に伴うホルモン遺伝子活性化のメカニズム

Principal Investigator

Project Period (FY)

Research Category

Research Institution

血液系腫瘍細胞におけるPRAD1/サイクリンD1の異常発現とその作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOTOKURA Toru 本倉徹

血液系腫瘍細胞における癌遺伝子D型サイクリンファミリーの発現様式の解析Principal Investigator