OHNISHI Akihiro 大西明弘

… Alternative Names

大西明弘オオニシアキヒロ

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Researcher Number	00194225
Affiliation (based on the past Project Information) *help	2006 – 2007: 東京慈恵会医科大学, 医学部, 助教授 2002 – 2004: 東京慈恵会医科大学, 医学部, 助教授 1996 – 1998: 東京慈恵会医科大学, 医学部, 講師 1990 – 1991: 東京慈恵会医科大学, 医学部, 講師 1989: 東京慈恵会医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator 応用薬理学・医療系薬学 / Laboratory medicine
Keywords	Principal Investigator genotype / 肝硬変 / hepatocellular carcinoma / P450 / detoxication / chronic Ctype virus hepatitis / liver cirrhosis / polymorphism / チトクロームP450 / C型肝炎 … More / 肝細胞癌 / 薬物遺伝 / 人種的多型 / 解毒 / 人種的差異 / 慢性C型肝炎 / 肝細胞癌(HCC) / angiotensin II / portal hypertension / natriuresis / thromboxane A_2 / prostacycline / noradrenaline / ascites / Liver cirrhosis / アンギオテンシン変換酵素 / 薬物療法 / ナトリウム利尿 / アンギオテンシンII / プロスタグランディン / 門脈圧亢進症 … More Except Principal Investigator 6β-hydroxycortisol / partial metabolic clearance / cortisol / lansoprazole / drug interaction / Helicobacter pylori / cytochrome P450 / clarithromycin / 6β水酸化コルチゾール / 部分代謝クリアランス / コルチゾール / ランソプラゾール / 薬物相互作用 / ヘリコバクターピロリ菌 / シトクロームP450 / クラリスロマイシン / ステロイド / LC-MS / ステロイドホルモン / 個人差 / 薬物代謝 Less

Studies on the urinary assay of CYP-mediated endogenous corticosteroid metabolites with a LC-MS method
- Principal Investigator
  
  ECHIZEN Hirotoshi
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Meiji Pharmaceutical University
Inhibition of CYP3A activity by a standard triple drug regimen including clarithromycin for eradication of Helicobacter pylori infection
- Principal Investigator
  
  ECHIZEN Hirotoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Meiji Pharmaceutical University
Genetic polymorphism in the cytochrome P450-2C19 genes in Japanese patients with hepatocellu-lar carcinoma and hepatitis C infectionPrincipal Investigator
- Principal Investigator
  
  OHNISHI Akihiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Dept.Int.Med., Daisan Hosp., Jikei University School of Medicine, Tokyo
Portal Hypertension in Liver Cirrhosis and Drug TherapyPrincipal Investigator
- Principal Investigator
  
  OHNISHI Akihiro
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The Jikei University School of Medicine

All 2009 2003 2002

All Journal Article

[Journal Article] Urinary Lipocalin-Type Prostaglandin D Synthase : A Potential Marker for Early Gentamicin-Induced Renal Damage?2009
- Author(s)
  Nakayama H, Echizen H, Gomi T, Shibuya Y, Nakamura Y, Nakano K, Arashi H, Ohnishi S, Tanaka M, Orii T
- Journal Title
  
  Ther Drug Monit 32
  
  Pages: 126-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590542
[Journal Article] Urinary Lipocalin Type Prosta- glandin D Synthase : A Potential Marker for Early Gentamicin-Induced Renal Damage?2009
- Author(s)
  Nakayama H, Echizen H, Gomi T, Shibuya Y, Nakamura Y, Nakano K, Arashi H, Ohnishi S, Tanaka M, Orii T
- Journal Title
  
  Ther Drug Monit 32
  
  Pages: 126-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590542
[Journal Article] Reduced urinary 6b-hydroxycortisol to cortisol rations in patients with liver cirrhosis2003
- Author(s)
  Shibuya Masahiko, Hirotoshi Echizen, Suzuko Kubo, Noboru Tamura, Koichi Suzuki, Hideki Ushiama, Akihiko Ohnishi
- Journal Title
  
  Hepatol Res 26
  
  Pages: 28-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572166
[Journal Article] Reduced urinary 6b-hydroxycortisol to cortisol ratios in patients with liver cirrhosis2003
- Author(s)
  Shibuya M, Echzien H, Kubo S, Tamura N, Suzuki K, Ushiama H, Ohnishi A
- Journal Title
  
  Hepatology Res 26
  
  Pages: 28-33
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572166
[Journal Article] 標準的3剤併用ヘリコバクターピロリ菌除菌療法におけるクラリスロマイシンの投与量依存的CYP3A阻害作用2003
- Author(s)
  越前宏俊, 牛尼秀樹, 大西明弘
- Journal Title
  
  臨床薬理 34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572166
[Journal Article] Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobactoer Pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6b-hydroxycortisol2002
- Author(s)
  Hideki Ushiama, Hirotoshi Echizen, Shinobu Nachi, Akihiro Ohnishi
- Journal Title
  
  Clin Pharmacol Ther 72
  
  Pages: 33-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572166
[Journal Article] Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in lansoprazole levels and partial cortisol clearance to 6(β-hydroxycortisol2002
- Author(s)
  Ushiama H, Echizen H, Nachi S, Ohnishi A
- Journal Title
  
  Clin Pharmacol Ther 72
  
  Pages: 33-43
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572166

1. ECHIZEN Hirotoshi (00191924)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. MURAKAMI Shigeto (20219893)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OSAKA Kazuhiro (30246384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 原田誠 (60221511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TSUCHIYA Takumi (80207406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 河合文平 (60281383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 村上誠

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHNISHI Akihiro 大西 明弘

大西 明弘 オオニシ アキヒロ

Research Projects

Research Products

Co-Researchers

Studies on the urinary assay of CYP-mediated endogenous corticosteroid metabolites with a LC-MS method

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of CYP3A activity by a standard triple drug regimen including clarithromycin for eradication of Helicobacter pylori infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic polymorphism in the cytochrome P450-2C19 genes in Japanese patients with hepatocellu-lar carcinoma and hepatitis C infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Portal Hypertension in Liver Cirrhosis and Drug TherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Urinary Lipocalin-Type Prostaglandin D Synthase : A Potential Marker for Early Gentamicin-Induced Renal Damage?2009

Author(s)

Journal Title

Data Source

[Journal Article] Urinary Lipocalin Type Prosta- glandin D Synthase : A Potential Marker for Early Gentamicin-Induced Renal Damage?2009

Author(s)

Journal Title

Data Source

[Journal Article] Reduced urinary 6b-hydroxycortisol to cortisol rations in patients with liver cirrhosis2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Reduced urinary 6b-hydroxycortisol to cortisol ratios in patients with liver cirrhosis2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] 標準的3剤併用ヘリコバクターピロリ菌除菌療法におけるクラリスロマイシンの投与量依存的CYP3A阻害作用2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobactoer Pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6b-hydroxycortisol2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in lansoprazole levels and partial cortisol clearance to 6(β-hydroxycortisol2002

Author(s)

Journal Title

Description

Data Source

OHNISHI Akihiro 大西明弘

大西明弘オオニシアキヒロ