ARAI Masazumi 荒井正純

Researcher Number	00202721
Affiliation *help	2006 : 岐阜大, 医学部附属病院, 講師 2003 – 2005 : 岐阜大学, 医学部附属病院, 講師 2004 : 岐阜大, 医学部附属病院, 講師 2003 : 岐阜大, 医学部附属病院, 助手 1999 – 2000 : 岐阜大, 医学部, 助手 2000 : 岐阜大学, 医学部・附属病院, 助手 1999 : 岐阜大学, 医学部, 助手
Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator NO / pravastatin / G-CSF / フリーラジカル / ハイドロキシラジカル / preconditioning / glycogen / 心筋梗塞サイズ / 一酸化窒素 / protein kinase C … More Except Principal Investigator G-CSF / 再生医療 / 顆粒球コロニー刺激因子 / DCMハムスターモデル / 梗塞後慢性心不全 / cardiomyocyte regeneration / 拡張型心筋症 / 慢性心不全 / CD34 / 心機能の改善 / autophagy / 虚血性末梢動脈疾患 / サイトカイン / 顆粒球コロニー刺激因子(G-CSF) / 血管新生 / 遺伝子治療 / アポトーシス / heart failure / 再生療法 / 狭心症 / dilated cardiomyopathy / CD34 positive cells / 心筋再生 / remodeling / apotosis / endothelial progenitor cell / cytokine / 繊維化抑制 / 微小血管の増殖 / 冠血流 / 好中球 / ハムスターUM-X7.1 / 血管内皮前駆細胞 / 骨髄細胞 / HGF / Regeneration therapy / proliferation of microvessel / G-CSF受容体 / ischemic peripheral artery disease / TNF-α / 心筋シンチ / リモデリング / 心不全 / MMP / Thallium 201 / 閉塞性動脈硬化症 / 心筋細胞再生 / Talium心筋シンチ / leukocytes / Angina / オートファジイ / regeneration therapy / オートファジー Less

Low invasive therapy with gratnilotyte colony stimulating factor in patients with coronary artery diceasePrincipal Investigator
- Principal Investigator
  
  MINATOGUCHI Shinya, 荒井正純
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Effect of Granulocyte Colony-Stimulating Factor Treatment at a Low Dose but Long Duration in Patients with Coronary Heart Disease
- Principal Investigator
  
  NISHIGAKI Kazuhiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  GIFU UNIVERSITY
Non-invasive regeneration therapy of dilated cardiomyopathy using G-CSF
- Principal Investigator
  
  FUJIWARA Hisayoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  GIFU UNIVERSITY
Clinical Application of Colony Stimulating Factor as a Non-invasive Regeneration Therapy against Ischemic Teripheral Artery DiseasePrincipal Investigator
- Principal Investigator
  
  ARAI Masazumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  GIFU UNIVERSITY
α-グルコシダーゼ阻害剤の梗塞縮小効果のメカニズムの解明-glycogenolysis抑制の下流側にK_<ATP> channelではなくprotein kinase Cがある-Principal Investigator
- Principal Investigator
  
  荒井正純
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University

All 2008 2007 2006 2004 2003

All Journal Article Presentation

[Journal Article] Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits2007
- Author(s)
  Bao, N., Minatoguchi, S., Kobayashi, H., Yasuda, S., Kawamura, I., Iwasa, M., Yamaki, T., Sumi, S., Misao, Y., Arai, M, Nishigaki, K., Takemura, G., Fujiwara, T., Fujiwara, H
- Journal Title
  
  Circ J 71
  
  Pages : 1622-1628
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590765
[Journal Article] Effect of Granulocyte Colony-Stimulating Factor Treatment at a Low Dose but for a Long Duration in Patients With Coronary Heart Disease-A Pilot Study-2006
- Author(s)
  Suzuki K, Nagashima K, Arai M, Uno Y, Misao Y, Takemura G, Nishigaki K, Minatoguchi S, Watanabe S, Tei C, Fujiwara H
- Journal Title
  
  Circ J 70(4)
  
  Pages : 430-437
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590668
[Journal Article] Effect of granulocyte colony-stimulating factor treatment at a low dose but for a long duration in patients with coronary heart disease -a pilot study2006
- Author(s)
  Suzuki, K., Nagashima, K., Arai, M, Uno, Y., Misao, Y., Takemura, G., Nishigaki, X, Minatoguchi, S., Watanabe, S., Tei, C., Fujiwara, H
- Journal Title
  
  Circ J 70
  
  Pages : 430-437
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590765
[Journal Article] 心筋梗塞後のリモデリング予防・サイトカイン療法の臨床2004
- Author(s)
  荒井正純, 藤原久義
- Journal Title
  
  Cardiovascular Med-Surg 6
  
  Pages : 304-309
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] Non-invasive Regeneration Therapy Using G-CSF Against Acute Myocardial Infarction2004
- Author(s)
  Masazumi Arai, Lu Chuanjuang, Yu Misao, Hiroshi Nagai, Xuehei Chen, Genzou Takemura, Shinya Minatoguchi, Hisayoshi Fujiwara.
- Journal Title
  
  Jpn J Electrocardiology 24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] Cytokine Therapy Using G-CSF Protects Post Infarct Myocardium From Remodeling2004
- Author(s)
  Masazumi Arai, Hisayoshi Fujiwara.
- Journal Title
  
  Cardiovascular Med-Surg 6
  
  Pages : 309-314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] 心筋梗塞後のリモデリング予防・サイトカイン療法の臨床2004
- Author(s)
  荒井正純, 藤原久義
- Journal Title
  
  Cardiovascular Med-Surg 6
  
  Pages : 309-314
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] 顆粒球コロニー刺激因子を用いた急性心筋梗塞の非侵襲的再生療法2004
- Author(s)
  荒井正純, 竹村元三, 藤原久義他
- Journal Title
  
  Jpn J Electrocardiology 24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment.2004
- Author(s)
  Minatoguchi S, Takemura G, Chen X, Wang N, Uno Y, Koda M, Arai M, Misao Y, Lu C, Suzuki K, Goto K, Komada A, Takahashi T, Kosai K, Fujiwara T, Fujiwara H
- Journal Title
  
  Circulation 109(21)
  
  Pages : 2572-2580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209027
[Journal Article] 心筋再生の現状と将来展望・G-CSFを用いた急性心筋梗塞治療の現状2003
- Author(s)
  荒井正純, 藤原久義
- Journal Title
  
  医学のあゆみ 207
  
  Pages : 927-930
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] 骨髄細胞を用いた心・血管再生療法2003
- Author(s)
  荒井正純
- Journal Title
  
  岐阜県医師会医学雑誌 16
  
  Pages : 63-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] Attempt of G-CSF-Mediated Regeneration Therapy Against Acute Myocardial Infarction2003
- Author(s)
  Masazumi Arai, Hisayoshi Fujiwara.
- Journal Title
  
  J Clinical Experimental Medicine (IGAKU NO AYUMI) 207
  
  Pages : 927-930
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Journal Article] Cardiovascular Regeneration Therapy With Bone Marrow Cells2003
- Author(s)
  Masazumi Arai.
- Journal Title
  
  J Gifu Medical Association 16
  
  Pages : 63-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590732
[Presentation] A low dose but long duration post-myocardial infarction treatment with granulocyte colony-stimulating factor shows a beneficial effect without any complications2008
- Author(s)
  Minatoguchi, S., Arai, M., Suzuki, K., Nishigaki, K., Takemura, G., Fujiwara, H
- Organizer
  The 72nd Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2008-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590765

1. FUJIWARA Hisayoshi (80115930)

# of Collaborated Projects : 3results

# of Collaborated Products : 9results
2. MINATOGUCHI Shinya (20190697)

# of Collaborated Projects : 3results

# of Collaborated Products : 5results
3. TAKEMURA Genzou (40283311)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
4. KOSAI Kenichirou (90258418)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
5. NISHIGAKI Kazuhiko (60198447)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results

ARAI Masazumi 荒井 正純

Research Projects

Research Products

Co-Researchers

Low invasive therapy with gratnilotyte colony stimulating factor in patients with coronary artery diceasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of Granulocyte Colony-Stimulating Factor Treatment at a Low Dose but Long Duration in Patients with Coronary Heart Disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Non-invasive regeneration therapy of dilated cardiomyopathy using G-CSF

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical Application of Colony Stimulating Factor as a Non-invasive Regeneration Therapy against Ischemic Teripheral Artery DiseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

α-グルコシダーゼ阻害剤の梗塞縮小効果のメカニズムの解明-glycogenolysis抑制の下流側にK_<ATP> channelではなくprotein kinase Cがある-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of Granulocyte Colony-Stimulating Factor Treatment at a Low Dose but for a Long Duration in Patients With Coronary Heart Disease-A Pilot Study-2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of granulocyte colony-stimulating factor treatment at a low dose but for a long duration in patients with coronary heart disease -a pilot study2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] 心筋梗塞後のリモデリング予防・サイトカイン療法の臨床2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Non-invasive Regeneration Therapy Using G-CSF Against Acute Myocardial Infarction2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Cytokine Therapy Using G-CSF Protects Post Infarct Myocardium From Remodeling2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 心筋梗塞後のリモデリング予防・サイトカイン療法の臨床2004

Author(s)

Journal Title

Data Source

[Journal Article] 顆粒球コロニー刺激因子を用いた急性心筋梗塞の非侵襲的再生療法2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 心筋再生の現状と将来展望・G-CSFを用いた急性心筋梗塞治療の現状2003

Author(s)

ARAI Masazumi 荒井正純