Miwa Hiroshi 三輪啓志

… Alternative Names

三輪啓志ミワヒロシ

MIWA Hroshi 三輪啓志

MIWA Hiroshi 三輪啓志

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Researcher Number	00209967
Other IDs
Affiliation (Current)	2022: 三重大学, 医学系研究科, 産学官連携講座准教授
Affiliation (based on the past Project Information) *help	2022: 三重大学, 医学系研究科, 産学官連携講座准教授 2020: 三重大学, 医学系研究科, 産学官連携講座准教授 2019: 三重大学, 医学系研究科, 特任准教授(研究担当) 2011: 愛知医科大学, 医学部, 教授 2009 – 2010: 愛知医科大学, 医学部, 准教授 … More 1993 – 1996: Mie University Hospital, Assistant, 医学部・附属病院, 助手 1995: Mie University, Mie University Hospital, Assistant, 医学部附属病院, 助手 1994: 医学部。附属病院, 助手 1991 – 1992: Mie University University Hospital, Assistant, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Hematology Except Principal Investigator Hematology / Hematology / General fisheries / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator CAR-T細胞 / エネルギー代謝 / 白血病 / 血液幹細胞 / WT-1 / MDR1 / 表現型 / CAR-T細胞療法 / 解糖阻害薬 Except Principal Investigator 悪性リンパ腫 … More / 免疫表現型 / リンパ系腫瘍 / 免疫遺伝子型 / 急性リンパ性白血病(ALL) / 急性骨髄性白血病(AML) / 造血幹細胞 / 細胞周期 / 造血因子 / TF / TFPI / TM / 白血病 / 食道癌 / 大腸癌 / stage / ストローマ / 薬剤耐性 / 成熟B細胞腫瘍 / B細胞分化 / CD5 / CD11c / Cμ遺伝子欠落 / 病態 / indolent型病型 / 二重遺伝子型 / 骨髄球系抗原 / B前駆細胞性腫瘍 / 急性分類不能白血病(AUL) / 予後 / lymphoid malignancy / immunophenotype / immunogenotype / dual genotype / AUL (acute unclassified leukemia) / mature B-cell malignancy / Cmu gene deletion / indolent type / IL-7受容体遺伝子発現 / c-hit遺伝子発現 / CD7陽性急性白血病 / CD5陽性B細胞リンパ腫 / PRAD-1遺伝子発現 / CD7陽性急性骨髄性白血病(AML) / B細胞リンパ腫 / c-kit遺伝子発現 / CD5発現 / Lymphoid malignanoy / Immunophenotype / Immunogenotyfe / IL-7 receptor gene expression / c-kit gene expression / CD7 positive acute leukemia / CD5 positive B-cell lymphona / PRAD-1 gone expression / 表現型 / 染色体異常 / 増殖因子受容体 / 多剤耐性遺伝子 / 幹細胞 / 白血病分類 / 造血因子受容体 / AML / ALL / Phenotype / chromosome / cytokine receptor / MDR1 gene / stem cell / AML classification / γδT細胞 / 遺伝子改変 Less

代謝改変によるCAR-T細胞療法の有効性向上の試みPrincipal Investigator
- Principal Investigator
  
  三輪啓志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Mie University
エネルギー代謝に注目した多機能遺伝子改変γδT細胞の追求
- Principal Investigator
  
  石原幹也
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Mie University
腫瘍細胞とキメラ抗原受容体Ｔ細胞のエネルギー代謝の相違に着目した次世代細胞治療Principal Investigator
- Principal Investigator
  
  三輪啓志
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Mie University
The Role of Reactive Oxygen Species In Apoptosis Induction of Mantle Cell Lymphoma(MCL); Inhibition of NADPH Oxidase 2 Induces Apoptosis In MCL
- Principal Investigator
  
  MIURA Yuji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Aichi Medical University
癌転移・浸潤における外因系止血機構、特に組織因子とそのインヒビターの役割
- Principal Investigator
  
  和田英夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
造血幹細胞の細胞周期に関する研究
- Principal Investigator
  
  KATAYAMA Naoyuki
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Mie University
Study for reconstitution of the AML classification on the basis of the biological characteristics.
- Principal Investigator
  
  KITA Kenkichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Mie University
がん抑制遺伝子WT-1の造血における役割と白血病発症への関与Principal Investigator
- Principal Investigator
  
  三輪啓志
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Mie University
Study on clinicoparhological characteristics of lymphoid malignaxcy based upon immunological and molecular biological analysis.
- Principal Investigator
  
  SHIRAKAWA Shigeru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General fisheries
- Research Institution
  Mie University
Pathological analyses of lymphoid malignancies based on immunological and molecular biological characteristics.
- Principal Investigator
  
  SHIRAKAWA Shigeru
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Mie University

All 2020 2019 2010

All Journal Article Presentation

[Journal Article] The Role of Reactive Oxygen Species In Apoptosis Induction of Mantle Cell Lymphoma(MCL)2010
- Author(s)
  Yuji Miura, Hiroshi Miwa, Toshihito Ohno, Miyako Haneda, Yoshitaka Hosokawa, Masakazu Nitta, and Masanori Daibata
- Journal Title
  
  Inhibition of NADPH Oxidase 2 Induces Apoptosis In MCL. Blood
  
  Volume: 116 Pages: 3616-3616
- Data Source
  KAKENHI-PROJECT-21591226
[Presentation] Accession of GITRL improves anti-leukemia functionality of CD19 CAR-T cells via metabolic behavior2020
- Author(s)
  三輪啓志、藤原弘、赤堀泰、王立楠、奥村悟志、田中義正、加藤琢磨、宮原慶裕、珠玖洋
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07751
[Presentation] グルココルチコイド誘導腫瘍壊死因子受容体リガンド（GITRL）付加による CD19 CAR-T細胞療法有効性向上の試み2020
- Author(s)
  三輪啓志、藤原弘、赤堀泰、王立楠、奥村悟志、田中義正、加藤琢磨、宮原慶裕、珠玖洋
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K07751
[Presentation] 有効性向上を目指したB細胞腫瘍に対する新たなCD19 CAR-T細胞療法の開発研究2019
- Author(s)
  三輪啓志、藤原　弘、赤堀　泰、王　立楠、奥村悟司、田中義正、加藤琢磨、宮原慶裕、珠玖　洋
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K07751
[Presentation] Development of novel CD19 CAR-T cell therapy with enhanced antitumor efficacy against B cell malignancies2019
- Author(s)
  三輪啓志、藤原　弘、赤堀　泰、王　立楠、奥村悟司、田中義正、加藤琢磨、宮原慶裕、珠玖　洋
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07751
[Presentation] Development of novel CD19 CAR-T cell therapy for B cell malignancies to improve its efficacy2019
- Author(s)
  三輪啓志、藤原　弘、赤堀　泰、王　立楠、奥村悟司、田中義正、加藤琢磨、宮原慶裕、珠玖　洋
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07751
[Presentation] The Role of Reactive Oxygen Species in Apoptosis Induction of Mantle Cell Lymphoma (MCL) ; Inhibition of NADPH Oxidase 2 Induces Apoptosis in MCL2010
- Author(s)
  Yuji Miura, Hiroshi Miwa, Toshihito Ohno, Miyako Haneda, Yoshitaka Hosokawa, Masakazu Nitta, Masanori Daibata
- Organizer
  第52回米国血液学会年次総会
- Place of Presentation
  オーランド(フロリダ州)
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21591226
[Presentation] The Role of Reactive Oxygen Species in Apoptosis Induction of Mantle Cell Lymphoma(MCL); Inhibition of NADPH Oxidase 2 Induces Apoptosis in MCL2010
- Author(s)
  Yuji Miura, Hiroshi Miwa, Toshihito Ohno, Miyako Haneda, Yoshitaka Hosokawa, Masakazu Nitta, Masanori Daibata
- Organizer
  第52回米国血液学会年次総会
- Place of Presentation
  米国フロリダ州オーランド
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21591226

1. KITA Kenkichi (90169847)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KATAYAMA Naoyuki (20185812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SHIRAKAWA Shigeru (20026850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OHNO Toshiyuki (50194246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NISHIKAWA Masakatsu (30144257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOBAYASHI Tohru (00144246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIURA Yuji (00345612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 和田英夫 (40158704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石原幹也 (20707369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Miwa Hiroshi 三輪 啓志

三輪 啓志 ミワ ヒロシ

MIWA Hroshi 三輪 啓志

MIWA Hiroshi 三輪 啓志

Research Projects

Research Products

Co-Researchers

代謝改変によるCAR-T細胞療法の有効性向上の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エネルギー代謝に注目した多機能遺伝子改変γδT細胞の追求

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍細胞とキメラ抗原受容体Ｔ細胞のエネルギー代謝の相違に着目した次世代細胞治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Role of Reactive Oxygen Species In Apoptosis Induction of Mantle Cell Lymphoma(MCL); Inhibition of NADPH Oxidase 2 Induces Apoptosis In MCL

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌転移・浸潤における外因系止血機構、特に組織因子とそのインヒビターの役割

Principal Investigator

Project Period (FY)

Research Category

Research Institution

造血幹細胞の細胞周期に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for reconstitution of the AML classification on the basis of the biological characteristics.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん抑制遺伝子WT-1の造血における役割と白血病発症への関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on clinicoparhological characteristics of lymphoid malignaxcy based upon immunological and molecular biological analysis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathological analyses of lymphoid malignancies based on immunological and molecular biological characteristics.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Role of Reactive Oxygen Species In Apoptosis Induction of Mantle Cell Lymphoma(MCL)2010

Author(s)

Journal Title

Data Source

[Presentation] Accession of GITRL improves anti-leukemia functionality of CD19 CAR-T cells via metabolic behavior2020

Author(s)

Organizer

Data Source

[Presentation] グルココルチコイド誘導腫瘍壊死因子受容体リガンド（GITRL）付加による CD19 CAR-T細胞療法有効性向上の試み2020

Author(s)

Organizer

Data Source

[Presentation] 有効性向上を目指したB細胞腫瘍に対する新たなCD19 CAR-T細胞療法の開発研究2019

Author(s)

Miwa Hiroshi 三輪啓志

三輪啓志ミワヒロシ

MIWA Hroshi 三輪啓志

MIWA Hiroshi 三輪啓志