MURAKAMI Nobutoshi 村上啓寿

Researcher Number	00210013
Other IDs
Affiliation (based on the past Project Information) *help	2009 – 2011: Kyoto Pharmaceutical University, 薬学部, 研究員 2006 – 2008: Osaka University, Graduate school of pharmaceutical sciences, Professor, 薬学研究科, 寄附講座教授 2002 – 2006: Osaka university Graduate School of Pharmaceutical Sciences Professor, 薬学研究科, 教授 1998 – 2001: 大阪大学, 薬学研究科, 助教授 1997: 大阪大学, 薬学部, 助教授 1995: Kyoto Pharmaceutical University Assistant Professor, 薬学部, 助教授 1993 – 1994: 京都薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Chemical pharmacy / Biological Sciences / Drug development chemistry / Chemical pharmacy / 医薬分子機能学 / Chemical biology Except Principal Investigator Chemical pharmacy / 医薬分子機能学
Keywords	Principal Investigator CRM1 / 核外移行シグナル / valtrate / 核外移行阻害活性 / MAPKK / callystatin A / 1'-acetoxychavicol acetate / 1'-acetoxylchavicol acetate / 抗癌剤 / malaria … More / 中央アフリカ / コンゴ民主共和国 / 中央アフリカ薬用植物 / マラリア / 抗がん剤 / 核外移行阻害剤 / 抗ガン剤 / 抗HIV剤 / 医薬リード化合物 / 薬用植物 / 抗エイズ薬 / Rev蛋白 / 天然物 / ポリケタイド / 沢瀉 / molecular orbital calculation / anti-tumor agents / anti-HIV agents / medicinal leads / inhibitor for nuclear export / nuclear export signal (NES) / 1)-acetoxychavicol acetate / 分子軌道計算 / artemisinin / biflavonoid / traditional antiinfectious medicinal plants / Central Africa / parasitic infectious disease / leishmania / trypanosome / プロアンソシアニジンン / アルテミシニン / ビフラボノイド / 抗寄生虫伝承薬用植物 / 寄生虫感染症 / リューシュマニア / トリパノソーマ / flavonoid-C-glycoside / iridoid / Democratic Republic of Congo / flavonol monoglycoside / traditional antimalarials / central Africa / medicinal plants / 成分探索 / 選択毒性 / フラボノイド配糖体 / 伝承薬 / 抗マラリア / コンゴ / イリドイド / フラボノイドC-グライコサイド / フラボノールモノグライコサイド / 薬剤耐性マラリア原虫 / 抗マラリア伝承薬 / anti-HIV / antttumors agent / Rev protein / nuclear export signal / 核外輸送シグナル / 標的蛋白 / 抗がん / 抗HIV / プローブ分子 / l'-acetoxychavicol acetate / peumusolide A / valtratre / 核外移行シグナル(NES) / HIV / カノコソウ / callystatinA / 抗腫瘍活性 / ファーマコフォー / 全合成 / 構造活性相関 / 細胞毒性 / 幼苗 / 再分化植物 / アシルトランスフェラーゼ / ジヒドロイソクマリン / サポニン / エルテラーゼ / アマチャ / カルス / sulfoorientalol / orientalol / thunberginol / alisol / 甘茶 / 制法 / 糖脂質 / 抗高脂血症 / トリテルペン / 抗アレルギー / 慈姑 / 植物プランクトン / 水生植物 … More Except Principal Investigator callystatin A / ニガキ科植物 / Brucea javanica / 鴉胆子 / カシノイド / 抗マラリア剤 / 細胞毒性 / 海綿 / arenastatin A / scoparianoside / トチノキ / タラノキ / agosterol A / bruceolide / ポリケタイド / がん多剤耐性 / 海洋生物 / depsipeptide / structure activity relationship / polyketide / marine sponge / cytotoxicity / anti-tumor / MRP / P-glycoprotein / araguspongine / がん多剤耐性克服物質 / 細胞毒性物質 / 軟サンゴ / 底生海洋生物 / senegasaponin / camelliasaponin / escin / elatoside / Chinese traditional medicine / anti-alcoholic principle / alcohol-absorption inhibitor / 構造活性相関 / サポニン / ツバキ / ムクロジ / ジヒドロフラボノール / hovenitin / ヒスタミン遊離抑制成分 / 肝障害抑制成分 / アルコール性筋弛緩抑制成分 / 枳子 / アルコール吸収抑制物質 / kochianoside / 抗潰瘍活性 / 地膚子 / 西洋トチノキ / セネガ / 肝障害抑制活性 / 筋弛緩抑制活性 / アルコール性潰瘍抑制活性 / アルコール吸収抑制活性 / 消酒生薬 / Gymnema sylvestre / Beta vulgaris / Aralia elata / Sagittaria trifolia / Zingiber officinale / Antidiabetic constituent / Antiallergic constituent / Medicinal foodstuff / 抗アレルギー / アマチャ / サトウダイコン / タラノメ / クワイ / ショウガ / 抗糖尿症作用 / 抗アレルギー作用 / 薬用食物 / 医食同源 / カーボネート / コンピュータグラフィックス / leptomycin B / 3,15-di-O-acetylbruceolide / デプシペプチド / 抗腫性 Less

Elucidation of new anti-tumor and anti-HIV target proteins by using probe molecules derived from bioactive natural productsPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Nobutoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto Pharmaceutical University
Exploration for New Medicinal Leads by Use of Natural Products Inhibiting Nuclear Export of Proteins as ScaffoldsPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Nobutoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University
Exploration for Traditional Anti-infectious Medicinal Plants in Central AfricaPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Nobutoshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka university
Search for Medicinal Leads Inhibiting Nuclear Export of NES-containing ProteinPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Nobutoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University
Exploration for Traditional Antimalarial Medicinal Plants in Central AfricaPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Nobutoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Osaka University
Rev蛋白核外移行阻害を標的とする天然由来抗エイズリード化合物の探索Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
MAPKK核外移行阻害天然物をシードとする新規抗癌剤の探索Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
NES保有蛋白の核外移行阻害を標的とする新規医薬リード化合物の探索Principal Investigator
- Principal Investigator
  
  MURAKAMI Nobutoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University
MAPKK核外移行阻害を標的とする天然由来新規抗癌剤の探索Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
天然カシイノド成分を利用した新規抗マラリア剤の創製
- Principal Investigator
  
  小林資正
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
天然カシノイドを利用した新規抗マラリア剤の創製
- Principal Investigator
  
  小林資正
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
海洋生物を起源とする機能探索分子の探索および創製
- Principal Investigator
  
  小林資正
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
超細胞毒性ポリケタイドcallystatinAの全合成と構造活性相関Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University
Search for New Anti-tumor Lead Compounds from Marine Organisms
- Principal Investigator
  
  KOBAYASHI Motomasa
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Osaka University
新しい抗がん剤の開発を志向する海洋天然物質の探索
- Principal Investigator
  
  KOBAYASHI Motomasa
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
天然カシノイド成分を利用した新規抗マラリア剤の創製
- Principal Investigator
  
  小林資正
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
植物培養細胞および生体触媒を利用した生物活性物質への化学変換研究Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Characterization of Alcohol-Absorption Inhibitors from Chinese Traditional Medicines with Anti-Alcoholic Activity
- Principal Investigator
  
  YOSHIKAWA Masayuki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
生薬制法の化学過程の解明に基づく生物有機化学的研究Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Search for Antiallergic and Antidiabetic Constituents from Oriental Medicinal Foodstuffs
- Principal Investigator
  
  YOSHIKAWA Masayuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
水生植物および植物プランクトンを基原とする薬理活性物質の探索研究Principal Investigator
- Principal Investigator
  
  村上啓寿
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University

All 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Patent

[Journal Article] Unprecedented NES non-antagonistic inhibitor for nuclear export of Rev from Sida cordifolia2010
- Author(s)
  Tamura, S.; Kaneko, M.; Shiomi A.; Yang G. M.; Yamaura T.; Murakami, N
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20 Pages: 1837-1839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603009
[Journal Article] Total synthesis of peumusolide A, NES non-antagonistic inhibitor for nuclear export of MEK2010
- Author(s)
  Tamura, S.; Doke, S.; Murakami, N
- Journal Title
  
  Tetrahedron
  
  Volume: 66 Pages: 8476-8480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603009
[Journal Article] Prenylcoumarin with Rev-export inhibitory activity from Cnidii Monnieris Fructus2010
- Author(s)
  Tamura, S.; Fujitani, T.; Kaneko, M.; Murakami, N
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20 Pages: 3717-3720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603009
[Journal Article] Stereo-controlled synthesis of analogs of peumusolide A, NES non-antagonistic inhibitor for nuclear export of MEK2010
- Author(s)
  Tamura, S.; Tonokawa, M.; Murakami, N
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 51 Pages: 3134-3137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603009
[Journal Article] New Rev Export Inhibitor from Alpinia galanga and Structure Activity Relationship2009
- Author(s)
  Tamura, S.; Shiomi, A.; Kaneko, M.; Ye, Y.; Yoshida, M.; Yoshikawa, M.; Kimura, T.; Kobayashi, M.; Murakami, N
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 19 Pages: 2555-2557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603009
[Journal Article] The 7^<th> forum of community research interchange from the fiftieth anniversary commemorative project of the faculty ofpharmaceutical sciences of Osaka university. "Exploration of new functions of plant resources"2007
- Author(s)
  村上啓寿
- Journal Title
  
  Foods Food Ingredients J. Jpn. 212
  
  Pages: 169-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590100
[Journal Article] Exploration of bioactive natural products from medicinal plants with novel mechanisms of action2007
- Author(s)
  村上啓寿
- Journal Title
  
  Foods Food Ingredients J. Jpn. 212
  
  Pages: 217-226
- NAID
  40015420311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590100
[Journal Article] The 7th forum of community research interchange from the fiftieth anniversary commemorative project of the faculty of pharmaceutical sciences of Osaka university. 'Exploration of new functions of plant resources'2007
- Author(s)
  村上啓寿
- Journal Title
  
  Foods Food Ingredients J. Jpn. 212
  
  Pages: 169-171
- Data Source
  KAKENHI-PROJECT-19590100
[Journal Article] α-リポ酸の製造工程で生成する重合物の安全性と構造解析2007
- Author(s)
  下田博司, 田中潤司, 関あずさ, 本田晴哉, 赤荻誠一郎, 小松原博文, 鈴木信夫, 亀山眞由美, 田村理, 村上啓寿
- Journal Title
  
  食衛誌 48
  
  Pages: 125-131
- NAID
  130000054316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590100
[Journal Article] 生物活性天然物をシーズとするプローブ分子の合成2006
- Author(s)
  村上啓寿, 田村理
- Journal Title
  
  ファルマシア 42
  
  Pages: 436-440
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Synthesis of probe molecules using bioactive natural products as seeds2006
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Farumashia 42 (5)
  
  Pages: 436-440
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Synthesis of probe molecules using bioactive natural products as seeds.2006
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Farumashia. 42 (5)
  
  Pages: 436-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Metabolic behavior of enzymatically modified isoquercitrin by α-amylase and gastric juices2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12(3)
  
  Pages: 162-165
- NAID
  110007367326
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Metabolic behavior of enzymatically modified isoquercitrin by α-amylase and gastric juices2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn. J. Food. Chem. 12 (3)
  
  Pages: 162-165
- NAID
  110007367326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Metabolic behavior of enzymatically modified isoquercitrin by α-amylase and gastric juices2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12(3)
  
  Pages: 162-165
- NAID
  110007367326
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Enhancement of anthocyanin content in red radish (Raphanus sativus L.). by γ-ray irradiation2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn. J. Food. Chem. 12 (3)
  
  Pages: 152-155
- NAID
  110007367328
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Kola acuminate proanthocyanidins : a class of anti-trypanosomal compounds effective against Trypanosoma brucei2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Int.J.Parasitology 35
  
  Pages: 91-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Metabolic behavior of enzymatically modified isoquercitrin by α-amylase and gastric juices2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food.Chem. 12(3)
  
  Pages: 162-165
- NAID
  110007367326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Enhancement of anthocyanin content in red radishes (Raphanus sativus L.) by γ-ray irradiation2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12(3)
  
  Pages: 152-155
- NAID
  110007367328
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Kola acuminata proanthocyanidins : a class of anti-trypanosomal compounds effective against Trypanosoma brucei.2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Int.J.Parasitology 35
  
  Pages: 91-103
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Enhancement of anthocyanin content in red radishes (Raphanus sativus L.) by γ-ray irradiation2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12(3)
  
  Pages: 152-155
- NAID
  110007367328
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Enhancement of anthocyanin content in red radish (Raphanus sativus L.) by γ-ray irradiation2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food.Chem. 12(3)
  
  Pages: 152-155
- NAID
  110007367328
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Kola acuminata proanthocyanidins : a class of anti-typanosomal compounds effective against Trypanosoma brucei.2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Int.J.Parasitology 35
  
  Pages: 91-103
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Enhancement of anthocyanin content in red radish (Raphanus sativus L.) by γ-ray irradiation2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12 (3)
  
  Pages: 152-155
- NAID
  110007367328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Kola acuminata proanthocyanidins : a class of anti-trypanosomal compounds effective against Trypanosoma brucei2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Int.J.Parasitology 35
  
  Pages: 91-103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Kola acuminate proanthocyanidins : a class of anti-trypanosomal compounds effective against Trypanosoma brucei2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Int.J.Parasitology 35
  
  Pages: 91-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Metabolic behavior of enzymatically modified isoquercitrin by α-amylase and gastric juices2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12 (3)
  
  Pages: 162-165
- NAID
  110007367326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Enhancement of anthocyanin content in red radish (Raphanus sativus L.) by γ-ray irradiation2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 12(3)
  
  Pages: 152-155
- NAID
  110007367328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Metabolic behavior of enzymatically modified isoquercitrin by α-amylase and gastric juices2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J Food Chem. 12(3)
  
  Pages: 162-165
- NAID
  110007367326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Kola acuminata proanthocyanidins : a class of anti-trypanosomal compounds effective against Trypanosoma brucei2005
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Int. J. Parasitology 35 (14)
  
  Pages: 91-103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxides2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14(13)
  
  Pages: 3513-3516
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Exploration for new anti-malarial leads using ingredients from medicinal plants as scaffolds2004
- Author(s)
  N.Murakami
- Journal Title
  
  Foods & Food Ingredients Journal of Japan 209(1)
  
  Pages: 60-66
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14(10)
  
  Pages: 2597-2601
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxide2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14 (13)
  
  Pages: 3513-3516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxides2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14(13)
  
  Pages: 3513-3516
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Exploration for new anti-malarial leads using ingredients from medicinal plants as scaffolds2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Foods ＆ Food Ingredients Journal of Japan 209 (1)
  
  Pages: 60-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 14 (10)
  
  Pages: 2597-2601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Comparative study on genetic diversity of two populations of red radish (Raphanus sativus L.) by AFLP analyses2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 11(3)
  
  Pages: 151-154
- NAID
  110007367302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Exploration for new anti-malarial leads using ingredients from medicinal plants as scaffolds2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Foods & Food Ingredients Journal of Japan 209(1)
  
  Pages: 60-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxides2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 14 (13)
  
  Pages: 3513-3516
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Comparative Study on Genetic Diversity of Two Populations of Red Radish (Raphanus sativus L.) by AFLP Analysis2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  日本食品化学会誌 11(3)
  
  Pages: 151-154
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Comparative Study on Genetic Diversity of Two Populations of Red Radish(Raphanus sativus L.) by AFLP Analysis2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  日本食品化学会誌 11(3)
  
  Pages: 151-154
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Comparative Study on Genetic Diversity of Two Population of Red Radish (Raphanus sativus L.) by AFLP Analysis2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  日本食品化学会誌 11(3)
  
  Pages: 151-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Exploration for new anti-malarial leads using ingredients from medicinal plants as scaffolds2004
- Author(s)
  N.Murakami
- Journal Title
  
  Foods & Food Ingredients Journal of Japan 209(1)
  
  Pages: 60-66
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Comparative study on genetic diversity of two populations of red radish (Raphanus sativus L.) by AFLP analyses2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn. J. Food Chem. 11 (3)
  
  Pages: 151-154
- NAID
  110007367302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14 (10)
  
  Pages: 2597-2601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14(10)
  
  Pages: 2597-2601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Journal Article] Comparative study on genetic diversity of two populations of red radish (Raphanus sativus L.) by AFLP analyses2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Jpn.J.Food Chem. 11 (3)
  
  Pages: 151-154
- NAID
  110007367302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxide2004
- Author(s)
  N.Murakami et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14(13)
  
  Pages: 3513-3516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Patent] MAPKK核外移行阻害物質peumusolideaの類縁体とその利用2008
- Inventor(s)
  村上啓寿, 他
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2008-02-22
- Overseas
- Data Source
  KAKENHI-PROJECT-19590100
[Patent] Preparation of peumusolide A analogues as MAPKK nuclear export inhibitors2008
- Inventor(s)
  N. Murakami、S. Tamura
- Industrial Property Rights Holder
  大阪大学、PCT Int. Appl
- Filing Date
  2008-02-22
- Overseas
- Data Source
  KAKENHI-PROJECT-19590100
[Patent] MAPKK核外移行阻害物質peumusolide Aの類縁体とその利用2007
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人, 大阪大学
- Filing Date
  2007-02-22
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] NES含有タンパク質核外移行阻害剤とその利用2006
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人, 大阪大学
- Filing Date
  2006-08-16
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] 1'-(アシルオキシ)シャビコールエステルハロゲン化物およびその利用2006
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Filing Date
  2006-09-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] NES含有タンパク質核外移行阻害剤とその利用2006
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Filing Date
  2006-08-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] 1'-(アシルオキシ)シャビコールエステルハロゲン化物およびその利用2006
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人, 大阪大学
- Filing Date
  2006-09-01
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] マスト細胞IgEレセプター発現抑制剤2005
- Inventor(s)
  村上啓寿, 田村理, 他
- Industrial Property Rights Holder
  国立大学法人大阪大学, 三栄源エフ・エフ・アイ株式会社
- Filing Date
  2005-06-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Patent] 新規MAPKK核移行阻害物質とその利用2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 独立行政法人科学技術振興機構
- Filing Date
  2005-01-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Patent] マスト細胞IgEレセプター発現抑制剤2005
- Inventor(s)
  村上啓寿, 田村理他
- Industrial Property Rights Holder
  国立大学法人大阪大学, 三栄源エフ・エフ・アイ株式会社
- Filing Date
  2005-06-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] 1'-アセトキシシャビコールアセテートの立体選択的化学合成法2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 独立行政法人科学技術振興機構
- Filing Date
  2005-01-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] NES非依存性MAPKK核外移行阻害物質2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 独立行政法人科学技術振興機構
- Industrial Property Number
  2005-023645
- Filing Date
  2005-01-31
- Data Source
  KAKENHI-PROJECT-16590007
[Patent] マスト細胞IgEレセプター発現抑制剤2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 三栄源エフ・エフ・アイ株式会社
- Filing Date
  2005-06-20
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] マスト細胞IgEレセプター発現抑制剤2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 三栄源エフ・エフ・アイ株式会社
- Filing Date
  2005-06-20
- Data Source
  KAKENHI-PROJECT-16590007
[Patent] NES非依存性MAPKK核外移行阻害物質2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 独立行政法人科学技術振興機構
- Industrial Property Number
  2005-023645
- Filing Date
  2005-01-31
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] 1'-アセトキシシャピコールアセテートの立体選択的化学合成法2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 独立行政法人科学技術振興機構
- Filing Date
  2005-01-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590007
[Patent] 新規MAPKK核移行阻害物質とその利用2005
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 独立行政法人科学技術振興機構
- Filing Date
  2005-01-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Patent] 赤潮原因藻駆除剤、及びそれを用いる赤潮防御方法2004
- Inventor(s)
  村上啓寿, 田村理
- Industrial Property Rights Holder
  国立大学法人大阪大学, 三栄源エフ・エフ・アイ株式会社
- Filing Date
  2004-08-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16406003
[Presentation] MEK 核外移行阻害物質peumusolide A の標的タンパクの探索2008
- Author(s)
  田村理、道家駿佑、服部雄飛、村上啓寿
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] MEK 核外移行阻害物質peumusolide A アナログの立体選択的合成2008
- Author(s)
  田村理、殿川雅之、村上啓寿
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] NES 含有蛋白核外移行阻害天然物valtrate の血中安定アナログ2008
- Author(s)
  田村理、藤堂慎吾、村上啓寿
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] 生薬“苦練皮"由来抗トリパノソーマ活性成分2008
- Author(s)
  村上啓寿, 他
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] MEK核外移行阻害物質peumusolide Aの標的タンパクの探索2008
- Author(s)
  村上啓寿, 他
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] NES含有蛋白核外移行阻害天然物valtrateの血中安定アナログ2008
- Author(s)
  村上啓寿, 他
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] 生薬 "苦練皮" 由来抗トリパノソーマ活性成分2008
- Author(s)
  田村理、Mifundu Michel Ngoma、村上啓寿
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] NES含有蛋白核外移行阻害活性valtrateのアナログ合成と生物活性2007
- Author(s)
  村上啓寿, 他
- Organizer
  第42回天然物談話会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] 標的タンパクとの結合モデルを用いた1'-acetoxychavicol acetateのアナログ設計と生物活性2007
- Author(s)
  村上啓寿, 他
- Organizer
  日本生薬学会第54回年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] 標的タンパクに対する結合モデルを用いた1' -acetoxychavicol acetate のアナログ設計と生物活性2007
- Author(s)
  田村理、塩見敦、小板橋央旭、村上啓寿
- Organizer
  第42回天然物談話会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] NES含有蛋白核外移行阻害物質valtrateのアナログ合成と生物活性2007
- Author(s)
  村上啓寿, 他
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] 標的タンパクとの結合モデルを用いた1' -acetoxychavicol acetate のアナログ設計と生物活性2007
- Author(s)
  田村理、塩見敦、小板橋央旭、村上啓寿
- Organizer
  日本生薬学会第54回年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] NES 含有蛋白核外移行阻害活性valtrate のアナログ合成と生物活性2007
- Author(s)
  田村理、藤堂慎吾、清水伸泰、藤原克昭、村上啓寿
- Organizer
  第42回天然物談話会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] NES 含有蛋白核外移行阻害物質valtrate のアナログ合成と生物活性2007
- Author(s)
  田村理、清水伸泰、藤原克昭、藤堂慎吾、村上啓寿
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590100
[Presentation] 標的タンパクに対する結合モデルを用いた1'-acetoxychavicol acetateのアナログ設計と生物活性2007
- Author(s)
  村上啓寿, 他
- Organizer
  第42回天然物談話会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590100

1. KOBAYASHI Motomasa (40116033)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. AOKI Shunji (60252699)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YOSHIKAWA Masayuki (90116129)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIMADA Hiromi (90268102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MURAKAMI Toshiyuki (40278445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAMURA Satoru (30362619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. MATSUDA Hisashi (40288593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TSUJI Koji (50359840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山口祥子 (60198744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MURAKAMI Nobutoshi 村上 啓寿

Research Projects

Research Products

Co-Researchers

Elucidation of new anti-tumor and anti-HIV target proteins by using probe molecules derived from bioactive natural productsPrincipal Investigator

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Exploration for New Medicinal Leads by Use of Natural Products Inhibiting Nuclear Export of Proteins as ScaffoldsPrincipal Investigator

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Exploration for Traditional Anti-infectious Medicinal Plants in Central AfricaPrincipal Investigator

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Search for Medicinal Leads Inhibiting Nuclear Export of NES-containing ProteinPrincipal Investigator

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Exploration for Traditional Antimalarial Medicinal Plants in Central AfricaPrincipal Investigator

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Rev蛋白核外移行阻害を標的とする天然由来抗エイズリード化合物の探索Principal Investigator

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MAPKK核外移行阻害天然物をシードとする新規抗癌剤の探索Principal Investigator

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NES保有蛋白の核外移行阻害を標的とする新規医薬リード化合物の探索Principal Investigator

Principal Investigator

Project Period (FY)

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MAPKK核外移行阻害を標的とする天然由来新規抗癌剤の探索Principal Investigator

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Project Period (FY)

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Review Section

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Principal Investigator

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Principal Investigator

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Principal Investigator

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超細胞毒性ポリケタイドcallystatinAの全合成と構造活性相関Principal Investigator

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Principal Investigator

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MURAKAMI Nobutoshi 村上啓寿