Shohab Youssefian ＳＹｏｕｓｓｅｆｉａｎ

Connect your ORCID iD *help

… Alternative Names

S Youssefian ショハブユーセフィアン

ユセフィアンショハブユセフィアンショハブ

ユーセフィアンショハブユーセフィアンショハブ

YOUSSEFIAN Shohab ユ-セフィアンショハブ

YOUSSEFIAN SHOHAB ユ-セフィアンショハブ

SHOHAB YOUSSEFIAN

YOUSSEFIAN S. YOUSSEFIAN S

Less

Researcher Number	00210576
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 京都大学, 医学研究科, 教授 2001: 秋田県立大学, 生物資源科学部, 助教授 2000: 秋田県立大学, 附属生物工学研究所, 助教授 1999: 秋田県立大学, 生物資源科学部, 助教授 1996 – 1997: 秋田県立農業短期大学, 附属生物工学研究所, 助教授 … More 1993 – 1995: 秋田県立農業短期大学, 附属生物工学研究所, 講師 1991: 秋田県立農業短期大学, 附属生物工学研究所, 講師 1991: Biotechnology Institute, Molecular Genetics, Lecturer, 講師 1990: 秋田県立農業短期大学, 生物工学研究所, 講師 1989: 秋田県立農業短期大学, 附属生物工学研究所, 助手 Less
Review Section/Research Field	Principal Investigator 植物生理 Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 56010:Neurosurgery-related / Society medicine, Nursing, and related fields / Complex systems / 植物生理学
Keywords	Principal Investigator トランスジェニック植物 / 小麦 / wgp / 小分子G-蛋白 / 酸素ストレス / Wgp / wgp7 / accessory proteins / transgenic plants / nitrogen dioxide … More / sulphur dioxide / oxidative stress / small G protein / GTP / wheat / パラコート / 二酸化窒素 / 二酸化硫黄 / 病原体感染 / 傷 / 一過的解析 / 傷応答 / 細胞死 / GTPase / 酸化ストレス / G蛋白質 / TRANSGENIC PLANTS / OXiDATIVS STRESS / NO_2 / SO_2 / SMALL G PROTEINS / WHEAT / プロモーター解析 / 組み換えタバコ / GTP結合タンパク質 / ras遺伝子 / コムギ … More Except Principal Investigator 疼痛 / RNF213 / もやもや病 / rgp1 / 組換えタバコ / モデルマウス / SCN10A / SCN11A / チャネロパチー / 寒冷暴露 / ＳＣＮ10Ａ / ＳＣＮ11Ａ / 寒冷 / 小児四肢疼痛発作症 / 細胞内シグナル / 血管閉塞 / 血管閉塞性疾患 / シグナル伝達 / 細胞内輸送 / 気象環境 / ナトリウムチャネル / 気象変化 / 気圧 / 温度 / 血管閉塞性病変 / R4810K変異 / 脳卒中 / 循環器疾患 / AAA+ / E3 ligase / ウイルス抗体の保有状況 / Mitotic failure / Arterial-Stenosis / RNF213-R4810K / 腸内細菌 / 細胞分裂 / R4810K / Apoptosis / ER stress / シグナル制御 / 感受性遺伝子 / 遺伝疫学 / transgenic tobacco / azacytidine / Oryza sativa / ras-related gene / small GTP-binding protein / dwarfism / DNA methylation / フザシチジン / 矮性イネ / rga1 / GTP結合蛋白質 / 矮性植物 / rasー関連遺伝子 / DNAメチル化 / アザシチジン / イネ / ras関連遺伝子 / 低分子量GTP結合タンパク質 / 矮性発現 / DNAのメチル化 / 硫化水素 / 酸性雨 / システイン合成酵素 / イオウ化合物 / 環境汚染 Less

Elucidation of infantile episodic limb pain mechanism induced by cold exposure
- Principal Investigator
  
  Okuda Hiroko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
  Kyoto University
Functional analysis of heritable risk factors for moyamoya disease and stroke
- Principal Investigator
  
  Tezuka Tohru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular society
- Principal Investigator
  
  Koizumi Akio
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Investigation of mechanisms of pain evoked by meteorological environment
- Principal Investigator
  
  Kouji Harada
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Research Field
  
  Society medicine, Nursing, and related fields
- Research Institution
  Kyoto University
Role of a small GTP-binding Protein in Oxidative Stress-Induced Cell Death in PlantsPrincipal Investigator
- Principal Investigator
  
  ユセフィアンショハブ (ユーセフィアンショハブ)
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  植物生理
- Research Institution
  Akita Prefectural University
Characterization of a plant gene encoding a small GTP-binding protein that is specifically induced by SO_2 and NO_2Principal Investigator
- Principal Investigator
  
  YOUSSEFIAN Shohab
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  植物生理
- Research Institution
  Biotechnology Institute, Akita Prefectural College of Agriculture
イオウを含む環境汚染物質の植物による浄化
- Principal Investigator
  
  SANO Hiroshi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita Prefectural College of Agriculture
Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator
- Principal Investigator
  
  YOUSSEFIAN SHOHAB
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  植物生理
- Research Institution
  Akita Prefectural College of Agriculture
Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator
- Principal Investigator
  
  SHOHAB YOUSSEFIAN
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  植物生理
- Research Institution
  Akita Prefectural College of Agriculture
Regulation of plant expression by DNA methylation
- Principal Investigator
  
  SANO Hiroshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  植物生理学
- Research Institution
  Akita Prefectural College of Agriculture

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] Moyamoya Disease: Current Knowledge and Future Perspectives2021
- Author(s)
  Hatasu Kobayashi, Kouji H. Harada, Toshiyuki Habu, Yasuhisa Nakamura, Jiyeong Kim, Akio Koizumi
- Total Pages
  341
- Publisher
  Springer Singapore
- Data Source
  KAKENHI-PLANNED-17H06397
[Journal Article] Posterior cerebral artery involvement in unilateral moyamoya disease is exclusively ipsilateral and influenced by RNF213 mutation gene dose: The SUPRA Japan study2024
- Author(s)
  Mineharu Yohei、Takagi Yasushi、Koizumi Akio、Morimoto Takaaki、Funaki Takeshi、Hishikawa Tomohito、Araki Yoshio、Hasegawa Hitoshi、Takahashi Jun C.、Kuroda Satoshi、Houkin Kiyohiro、Miyamoto Susumu
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 33 Issue: 2 Pages: 107513-107513
- DOI
  10.1016/j.jstrokecerebrovasdis.2023.107513
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24444, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19H03770
[Journal Article] Peripheral blood GATA2 expression impacts RNF213 mutation penetrance and clinical severity in moyamoya disease2024
- Author(s)
  Yohei Mineharu, Takahiko Kamata, Mei Tomoto, Noriaki Sato, Yoshinori Tamada, Takeshi Funaki, Yuki Oichi, Koji H Harada, Akio Koizumi, Tetsuaki Kimura, Ituro Inoue, Yasushi Okuno, Susumu Miyamoto, and Yoshiki Arakawa
- Journal Title
  
  medRxiv
  
  Volume: June 28
- DOI
  10.1101/2024.06.22.24306750
- Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19H03770
[Journal Article] Reduced pain sensitivity of episodic pain syndrome model mice carrying a Nav1.9 mutation by ANP-230, a novel sodium channel blocker2023
- Author(s)
  Hiroko Okuda, Sumiko Inoue, Yoshihiro Oyamada, Shohab Youssefian, Akio Koizumi
- Journal Title
  
  Heliyon
  
  Volume: 9(4) Issue: 4 Pages: e15423-e15423
- DOI
  10.1016/j.heliyon.2023.e15423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10394
[Journal Article] Moyamoya disease: diagnosis, and interventions2022
- Author(s)
  Masafumi Ihara, Yumi Yamamoto, Yorito Hattori, Wanyang Liu, Hatasu Kobayashi, Hiroyuki Ishiyama, Takeshi Yoshimoto, Satoru Miyawaki, Tim Clausen, Oh Young Bang, Gary K. Steinberg, Elisabeth Tournier-Lasserve, Akio Koizumi
- Journal Title
  
  Lancet Neurology
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Journal Article] Genetic and nongenetic factors for contralateral progression of unilateral moyamoya disease: the first report from the SUPRA Japan Study Group2022
- Author(s)
  Mineharu Yohei、Takagi Yasushi、Koizumi Akio、Morimoto Takaaki、Funaki Takeshi、Hishikawa Tomohito、Araki Yoshio、Hasegawa Hitoshi、Takahashi Jun C.、Kuroda Satoshi、Houkin Kiyohiro、Miyamoto Susumu
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: 136 Issue: 4 Pages: 1005-1014
- DOI
  10.3171/2021.3.jns203913
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19H03770
[Journal Article] Lack of association between seropositivity of vasculopathy-related viruses and moyamoya disease.2022
- Author(s)
  Nakamura Y, Mineharu Y, Kamata T, Funaki T, Susumu M, Koizumi A, Harada HK
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06397
[Journal Article] Suppression of RNF213, a susceptibility gene for moyamoya disease, inhibits endoplasmic reticulum stress through SEL1L upregulation2022
- Author(s)
  Ahmed Sharif、Habu Toshiyuki、Kim Jiyeong、Okuda Hiroko、Oikawa Shinji、Murata Mariko、Koizumi Akio、Kobayashi Hatasu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 609 Pages: 62-68
- DOI
  10.1016/j.bbrc.2022.04.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-22K10487, KAKENHI-PROJECT-21K19640, KAKENHI-PROJECT-19KK0238, KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-23K24589, KAKENHI-PROJECT-19H03885
[Journal Article] Characterization of Moyamoya and Middle Cerebral Artery Diseases by Carotid Canal Diameter and RNF213 p.R4810K Genotype2022
- Author(s)
  Oichi Yuki、Mineharu Yohei、Agawa Yuji、Morimoto Takaaki、Funaki Takeshi、Hitomi Toshiaki、Kobayashi Hatasu、Todo Kenichi、Tani Shoichi、Imamura Hirotoshi、Yoshida Kazumichi、Kataoka Hiroharu、Koizumi Akio、Sakai Nobuyuki、Miyamoto Susumu
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 31 Issue: 6 Pages: 106481-106481
- DOI
  10.1016/j.jstrokecerebrovasdis.2022.106481
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19H03770, KAKENHI-PROJECT-22K10487, KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-23K24589, KAKENHI-PROJECT-23K24444
[Journal Article] Socio‐economic factors do also matter: comments on the article “Can climatic factors explain the differences in COVID-19?incidence and severity across the spanish regions?: an ecological study”2021
- Author(s)
  Phosri Arthit、Cao Yang、Harada Sassa Mariko、Harada Kouji H.
- Journal Title
  
  Environmental Health
  
  Volume: 20 Issue: 1 Pages: 17-17
- DOI
  10.1186/s12940-021-00701-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20308
[Journal Article] UBC13 is an RNF213-associated E2 ubiquitin-conjugating enzyme, and Lysine 63-linked ubiquitination by the RNF213UBC13 axis is responsible for angiogenic activity.2021
- Author(s)
  Habu T, Harada K
- Journal Title
  
  FASEB Bioadv.
  
  Volume: 3 Issue: 4 Pages: 243-258
- DOI
  10.1096/fba.2019-00092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06397
[Journal Article] Intranasal levels of lead estimated from airborne pollen and urinary lead levels in Japan2021
- Author(s)
  Nanayakkara Shanika、Yamamoto Naomichi、Harada Kouji H.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 148 Issue: 2 Pages: 654-655
- DOI
  10.1016/j.jaci.2021.05.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20308
[Journal Article] RNF213 p.R4810K (c.14429G > A) Variant Determines Anatomical Variations of the Circle of Willis in Cerebrovascular Disease2021
- Author(s)
  Eto Futoshi、Yoshimoto Takeshi、Okazaki Shuhei、Nishimura Kunihiro、Ogura Shiori、Yamaguchi Eriko、Fukuma Kazuki、Saito Satoshi、Washida Kazuo、Koga Masatoshi、Toyoda Kazunori、Morimoto Takaaki、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 681743-681743
- DOI
  10.3389/fnagi.2021.681743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922
[Journal Article] E44Q mutation in NaV1.7 in a patient with infantile paroxysmal knee pain: electrophysiological analysis of voltage-dependent sodium current2021
- Author(s)
  Takahashi Kiichi、Ohba Takayoshi、Okamoto Yosuke、Noguchi Atsuko、Okuda Hiroko、Kobayashi Hatasu、Harada Kouji H.、Koizumi Akio、Ono Kyoichi、Takahashi Tsutomu
- Journal Title
  
  Heliyon
  
  Volume: 7 Issue: 6 Pages: e07396-e07396
- DOI
  10.1016/j.heliyon.2021.e07396
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20308, KAKENHI-PROJECT-20K16116
[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFκB activation and apoptosis in an AAA+ domain-dependent manner2020
- Author(s)
  Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Issue: 3 Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-20H03790
[Journal Article] Mechanical allodynia triggered by cold exposure in mice with the Scn11a p.R222S mutation: a novel model of drug therapy for neuropathic pain related to NaV1.92020
- Author(s)
  Matsubara Yosuke、Okuda Hiroko、Harada Kouji H.、Youssefian Shohab、Koizumi Akio
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology
  
  Volume: 394 Issue: 2 Pages: 299-306
- DOI
  10.1007/s00210-020-01978-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20308
[Journal Article] Moyamoya Disease and Spectrums of RNF213 Vasculopathy.2020
- Author(s)
  Bang OY, Chung JW, Kim DH, Won HH, Yeon JY, Ki CS, Shin HJ, Kim JS, Hong SC, Kim DK, Koizumi A
- Journal Title
  
  Translational Stroke Research
  
  Volume: － Issue: 4 Pages: 580-589
- DOI
  10.1007/s12975-019-00743-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Journal Article] Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis2019
- Author(s)
  Okazaki S, Koizumi A 他26名(27番目)
- Journal Title
  
  Circulation
  
  Volume: 139 Issue: 2 Pages: 295-298
- DOI
  10.1161/circulationaha.118.038439
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H03596
[Journal Article] Prevalence of RNF213 p.R4810K Variant in Early-Onset Stroke With Intracranial Arterial Stenosis2019
- Author(s)
  Kamimura Teppei、Okazaki Shuhei、Morimoto Takaaki、Kobayashi Hatasu、Harada Kouji、Tomita Tsutomu、Higashiyama Aya、Yoshimoto Takeshi、Takahashi Jun C.、Nakagawara Jyoji、Koga Masatoshi、Toyoda Kazunori、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
- Journal Title
  
  Stroke
  
  Volume: 50 Issue: 6 Pages: 1561-1563
- DOI
  10.1161/strokeaha.118.024712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06922, KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-17H04670
[Journal Article] Familial episodic limb pain in kindreds with novel Nav1.9 mutations2018
- Author(s)
  Kabata R, Okuda H, Noguchi A, Kondo D, Fujiwara M, Hata K, Kato Y, Ishikawa K, Tanaka M, Sekine Y, Hishikawa N, Mizukami T, Ito J, Akasaka M, Sakurai K, Yoshida T, Minoura H, Hayashi T, Inoshita K, Matsuyama M, Kinjo N, Cao Y, Inoue S, Kobayashi H, Harada KH, Youssefian S, Takahashi T, Koizumi A.
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 12 Pages: e0208516-e0208516
- DOI
  10.1371/journal.pone.0208516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-20K20308
[Journal Article] Dysregulation of RNF213 promotes cerebral hypoperfusion2018
- Author(s)
  Morimoto T, Enmi J, Hattori Y, Iguchi S, Saito S, Harada K, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 3607-3607
- DOI
  10.1038/s41598-018-22064-8
- NAID
  120006510289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K19243, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19963
[Journal Article] EXPRESS: Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice2018
- Author(s)
  Kobayashi Hatasu、Kabata Risako、Kinoshita Hideyuki、Morimoto Takaaki、Ono Koh、Takeda Midori、Choi Jungmi、Okuda Hiroko、Liu Wanyang、Harada Kouji H、Kimura Takeshi、Youssefian Shohab、Koizumi Akio
- Journal Title
  
  Pulmonary Circulation
  
  Volume: - Issue: 3 Pages: 204589401877815-204589401877815
- DOI
  10.1177/2045894018778155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-15K09137, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06397
[Presentation] Naチャネル阻害薬ANP-230の小児四肢疼痛発作症に対する疼痛抑制効果の検証.2024
- Author(s)
  奥田　裕子、井上　純子、小山田義博、Shohab Youseffian、小泉　昭夫.
- Organizer
  第93回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-21K10394
[Presentation] Analgesic effects of a novel sodium channel blocker on a mouse model of episodic pain syndrome.2024
- Author(s)
  Okuda H, Inoue S, Oyamada Y, Koizumi K, Youssefian S.
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10394
[Presentation] 新規のナトリウムチャネル阻害薬であるANP-230は小児四肢疼痛発作症のモデルマウスの疼痛発作を抑制する.2024
- Author(s)
  奥田　裕子、井上　純子、小山田義博、Shohab Youseffian、小泉　昭夫.
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K10394
[Presentation] 新規のナトリウムチャネル阻害薬であるANP-230は小児四肢疼痛発作症のモデルマウスの疼痛発作を抑制する2023
- Author(s)
  奥田　裕子、井上　純子、小山田義博、Shohab Youseffian、小泉　昭夫
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K10394
[Presentation] Naチャネル阻害薬ANP-230の小児四肢疼痛発作症に対する疼痛抑制効果の検証2023
- Author(s)
  奥田　裕子、井上　純子、小山田義博、Shohab Youseffian、小泉　昭夫
- Organizer
  第93回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-21K10394
[Presentation] もやもや病患者のiPS細胞由来内皮細胞におけるRNF213変異の影響2022
- Author(s)
  尾市雄輝、峰晴陽平、吉岡美樹、手塚徹、Kuan-Chun Lan、藤渕航、香川晴信、松本智子、Knut Woltjen、小泉昭夫、宮本享、山下潤、Shohab Youssefian
- Organizer
  STROKE 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病の疾患モデルiPS細胞に対する遺伝子修復の効果2022
- Author(s)
  尾市雄輝、峰晴陽平、吉岡美樹、手塚徹、Kuan-Chun Lan、藤渕航、香川晴信、松本智子、Knut Woltjen、小泉昭夫、宮本享、山下潤、Shohab Youssefian
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] Effect of RNF213 suppression on endoplasmic reticulum stress2022
- Author(s)
  Ahmed Sharif, 小林果, 土生敏行, 原田浩二 , 手塚徹, Youssefian Shohab, 及川伸二, 村田真理子, 小泉昭夫
- Organizer
  第92回　日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] 小児四肢疼痛発作症モデルマウスの減圧に対する疼痛行動解析2022
- Author(s)
  奥田裕子、杉昌樹、原田浩二、Shohab Youseffian、小泉昭夫
- Organizer
  第92回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K20308
[Presentation] もやもや病患者のiPS細胞由来内皮細胞におけるRNF213変異の影響2022
- Author(s)
  尾市雄輝、峰晴陽平、吉岡美樹、手塚徹、Lan Kuan-Chun、藤渕航、香川晴信、松本智子、Woltjen Knut、小泉昭夫、宮本享、山下潤、Youssefian Shohab
- Organizer
  STROKE 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] Effect of RNF213 suppression on endoplasmic reticulum stress2022
- Author(s)
  Sharif Ahmed, 小林果, 土生敏行, 原田浩二 , 手塚徹, Shohab Youssefian, 及川伸二, 村田真理子, 小泉昭夫
- Organizer
  第92回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213における結合蛋白質の制御機構の解明2021
- Author(s)
  崔廷米、手塚徹、小林果、原田浩二、小泉昭夫、Youssefian Shohab
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] Rnf213抑制はオスAkitaマウスと異なりメスAkitaマウスの糖尿病を改善しない2021
- Author(s)
  Sharif Ahmed, 小林果, 奥田裕子, 原田浩二, 土生敏行, Shohab Youssefian, 及川伸二, 村田真理子, 小泉昭夫
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213における結合蛋白質の制御機構の解明2021
- Author(s)
  崔廷米、手塚徹、小林果、原田浩二、小泉昭夫、Youssefian Shohab
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] 小児四肢疼痛発作症の神経過興奮メカニズム解明のためのNav1.8欠損マウスの作出2021
- Author(s)
  奥田裕子、竹谷朱、小林果、土生敏行、原田浩二、ユーセフィアン・ショハブ、小泉昭男
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K20308
[Presentation] RNF213 調節不全は両側総頸動脈狭窄マウスモデルの脳低灌流を悪化させる2020
- Author(s)
  小林　果、森本　貴昭、原田　浩二、奥田　裕子、 Shohab Youssefian、及川　伸二、村田　真理子、小泉　昭夫
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213 の結合蛋白質の同定2020
- Author(s)
  崔　廷米、武田　美都里、小林　果、手塚　徹、原田　浩二、小泉　昭夫、Youssefian Shohab
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子RNF213の結合分子の同定2019
- Author(s)
  崔廷米, 井上令一, 武田美都里, 小林果, 手塚徹, 原田浩二, 小泉昭夫, Youssefian Shohab
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] Rnf213遺伝子改変マウスにおける免疫細胞・血清サイトカインの系統的解析2019
- Author(s)
  小林果, 西村泰光, 奥田裕子, 原田浩二, 加畑理咲子, 武田美都里, 崔廷米, Youssefian Shohab, 大槻剛巳, 小泉昭夫
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213のユビキチンリガーゼ活性の検討2019
- Author(s)
  武田美都里, 手塚徹, 金びん秀, 西出旭, 崔廷米, 原田浩二, 小泉昭夫, ショハブ・ユーセフィアン
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] The Prevalence of RNF213 p.R4810K Variant is High in Juvenile-Onset Stroke Patients With Intracranial Arterial Stenosis2018
- Author(s)
  Teppei Kamimura, Shuhei Okazaki, Takaaki Morimoto, Hatasu Kobayashi, Kouji Harada, Tsutomu Tomita, Aya Higashiyama, Jun C Takahashi, Jyoji Nakagawara, Kazunori Toyoda, Akio Koizumi, Masafumi Ihara
- Organizer
  International Stroke Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] mysterin 遺伝子の肺高血圧症患者遺伝子スクリーニングおよびマウスモデルによる解析2018
- Author(s)
  小林果、加畑理咲子、木下秀之、森本貴昭、武田美都里、崔廷米、奥田裕子、原田浩二、Youssefian　Shohab、小泉昭夫
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病タンパク質RNF213 のE3 ligase活性の機能的評価2018
- Author(s)
  武田美都里、キムミンソ、小林果、原田浩二、土生敏行、小泉昭夫、ユーセフィアン　ショハブ
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397

1. SANO Hiroshi (20178809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Koizumi Akio (50124574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
3. Tezuka Tohru (50312319)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. Kouji Harada (80452340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
5. Okuda Hiroko (30709663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. 小林果 (70542091)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
7. 土生敏行 (70346071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 高橋勉 (20270845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 尾野恭一 (70185635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. Kim Minsoo (50466835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 水島恒裕 (90362269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高橋淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 宮本享

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 峰晴陽平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 猪原匡史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 岡崎周平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shohab Youssefian Ｓ Ｙｏｕｓｓｅｆｉａｎ

S Youssefian ショハブ ユーセフィアン

ユセフィアン ショハブ ユセフィアン ショハブ

ユーセフィアン ショハブ ユーセフィアン ショハブ

YOUSSEFIAN Shohab ユ-セフィアン ショハブ

YOUSSEFIAN SHOHAB ユ-セフィアン ショハブ

SHOHAB YOUSSEFIAN

YOUSSEFIAN S. YOUSSEFIAN S

Research Projects

Research Products

Co-Researchers

Elucidation of infantile episodic limb pain mechanism induced by cold exposure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of heritable risk factors for moyamoya disease and stroke

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular society

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of mechanisms of pain evoked by meteorological environment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of a small GTP-binding Protein in Oxidative Stress-Induced Cell Death in PlantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of a plant gene encoding a small GTP-binding protein that is specifically induced by SO_2 and NO_2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

イオウを含む環境汚染物質の植物による浄化

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of plant expression by DNA methylation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Moyamoya Disease: Current Knowledge and Future Perspectives2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Posterior cerebral artery involvement in unilateral moyamoya disease is exclusively ipsilateral and influenced by RNF213 mutation gene dose: The SUPRA Japan study2024

Author(s)

Journal Title

DOI

Data Source

Shohab Youssefian ＳＹｏｕｓｓｅｆｉａｎ

S Youssefian ショハブユーセフィアン

ユセフィアンショハブユセフィアンショハブ

ユーセフィアンショハブユーセフィアンショハブ

YOUSSEFIAN Shohab ユ-セフィアンショハブ

YOUSSEFIAN SHOHAB ユ-セフィアンショハブ

[Journal Article] RNF213 p.R4810K (c.14429G > A) Variant Determines Anatomical Variations of the Circle of Willis in Cerebrovascular Disease2021