Shohab Youssefian ＳＹｏｕｓｓｅｆｉａｎ

… Alternative Names

Researcher Number	00210576
Other IDs
Affiliation (Current)	2021: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2020: 京都大学, 医学研究科, 教授 2001: 秋田県立大学, 生物資源科学部, 助教授 2000: 秋田県立大学, 附属生物工学研究所, 助教授 1999: 秋田県立大学, 生物資源科学部, 助教授 1996 – 1997: 秋田県立農業短期大学, 附属生物工学研究所, 助教授 … More
Review Section/Research Field	Principal Investigator 植物生理 Except Principal Investigator 植物生理学 / Complex systems / Society medicine, Nursing, and related fields / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator wgp / 小麦 / トランスジェニック植物 / wgp7 / Wgp / 酸素ストレス / 小分子G-蛋白 / コムギ / ras遺伝子 / GTP結合タンパク質 … More Except Principal Investigator 組換えタバコ / rgp1 / RNF213 / もやもや病 / 環境汚染 / イオウ化合物 / システイン合成酵素 / 酸性雨 / 硫化水素 / DNAのメチル化 / 矮性発現 / 低分子量GTP結合タンパク質 / ras関連遺伝子 / イネ / アザシチジン / DNAメチル化 / rasー関連遺伝子 / 矮性植物 / GTP結合蛋白質 / rga1 / 矮性イネ / フザシチジン / DNA methylation / dwarfism / small GTP-binding protein / ras-related gene / Oryza sativa / azacytidine / transgenic tobacco / RNF213-R4810K / Arterial-Stenosis / ER stress / Mitotic failure / 腸内細菌 / ウイルス抗体の保有状況 / E3 ligase / AAA+ / R4810K / Apoptosis / 循環器疾患 / 脳卒中 / R4810K変異 / 血管閉塞性病変 / 疼痛 / ナトリウムチャネル / 温度 / 細胞内輸送 / 気象環境 / 血管閉塞性疾患 / 細胞内シグナル Less

もやもや病や脳梗塞の遺伝性リスク因子の機能解析Ongoing
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular societyOngoing
- Principal Investigator
  
  小泉昭夫
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Investigation of mechanisms of pain evoked by meteorological environmentOngoing
- Principal Investigator
  
  原田浩二
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Research Field
  
  Society medicine, Nursing, and related fields
- Research Institution
  Kyoto University
Role of a small GTP-binding Protein in Oxidative Stress-Induced Cell Death in PlantsPrincipal Investigator
- Principal Investigator
  
  ユセフィアンショハブ (ユーセフィアンショハブ)
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  植物生理
- Research Institution
  Akita Prefectural University
Characterization of a plant gene encoding a small GTP-binding protein that is specifically induced by SO_2 and NO_2Principal Investigator
- Principal Investigator
  
  YOUSSEFIAN Shohab
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  植物生理
- Research Institution
  Biotechnology Institute, Akita Prefectural College of Agriculture
イオウを含む環境汚染物質の植物による浄化
- Principal Investigator
  
  SANO Hiroshi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita Prefectural College of Agriculture
Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator
- Principal Investigator
  
  YOUSSEFIAN SHOHAB
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  植物生理
- Research Institution
  Akita Prefectural College of Agriculture
Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator
- Principal Investigator
  
  SHOHAB YOUSSEFIAN
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  植物生理
- Research Institution
  Akita Prefectural College of Agriculture
Regulation of plant expression by DNA methylation
- Principal Investigator
  
  SANO Hiroshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  植物生理学
- Research Institution
  Akita Prefectural College of Agriculture

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFkB activation and apoptosis in an AAA+domain-dependent manne2020
- Author(s)
  Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: - Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786
[Journal Article] Moyamoya Disease and Spectrums of RNF213 Vasculopathy.2020
- Author(s)
  Bang OY, Chung JW, Kim DH, Won HH, Yeon JY, Ki CS, Shin HJ, Kim JS, Hong SC, Kim DK, Koizumi A
- Journal Title
  
  Translational Stroke Research
  
  Volume: －
- DOI
  10.1007/s12975-019-00743-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Journal Article] Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis.2019
- Author(s)
  Okazaki S, Koizumi A 他26名(27番目)
- Journal Title
  
  Circulation.
  
  Volume: 139 Pages: 295-298
- DOI
  10.1161/circulationaha.118.038439
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H03596
[Journal Article] Prevalence of RNF213 p.R4810K Variant in Early-Onset Stroke With Intracranial Arterial Stenosis2019
- Author(s)
  Kamimura Teppei、Okazaki Shuhei、Morimoto Takaaki、Kobayashi Hatasu、Harada Kouji、Tomita Tsutomu、Higashiyama Aya、Yoshimoto Takeshi、Takahashi Jun C.、Nakagawara Jyoji、Koga Masatoshi、Toyoda Kazunori、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
- Journal Title
  
  Stroke
  
  Volume: 50 Pages: 1561-1563
- DOI
  10.1161/strokeaha.118.024712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06922, KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-17H04670
[Journal Article] Dysregulation of RNF213 promotes cerebral hypoperfusion2018
- Author(s)
  Morimoto T, Enmi J, Hattori Y, Iguchi S, Saito S, Harada K, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Pages: 3607-3607
- DOI
  10.1038/s41598-018-22064-8
- NAID
  120006535057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K19243, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19963
[Journal Article] Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice2018
- Author(s)
  Kobayashi Hatasu、Kabata Risako、Kinoshita Hideyuki、Morimoto Takaaki、Ono Koh、Takeda Midori、Choi Jungmi、Okuda Hiroko、Liu Wanyang、Harada Kouji H、Kimura Takeshi、Youssefian Shohab、Koizumi Akio
- Journal Title
  
  Pulmonary Circulation
  
  Volume: - Pages: 204589401877815-204589401877815
- DOI
  10.1177/2045894018778155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-15K09137, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06397
[Journal Article] Familial episodic limb pain in kindreds with novel Nav1.9 mutations2018
- Author(s)
  Kabata R, Okuda H, Noguchi A, Kondo D, Fujiwara M, Hata K, Kato Y, Ishikawa K, Tanaka M, Sekine Y, Hishikawa N, Mizukami T, Ito J, Akasaka M, Sakurai K, Yoshida T, Minoura H, Hayashi T, Inoshita K, Matsuyama M, Kinjo N, Cao Y, Inoue S, Kobayashi H, Harada KH, Youssefian S, Takahashi T, Koizumi A.
- Journal Title
  
  PLOS ONE
  
  Volume: 13
- DOI
  10.1371/journal.pone.0208516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-20K20308
[Presentation] もやもや病感受性遺伝子産物RNF213 の結合蛋白質の同定2020
- Author(s)
  崔　廷米、武田　美都里、小林　果、手塚　徹、原田　浩二、小泉　昭夫、Youssefian Shohab
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] RNF213 調節不全は両側総頸動脈狭窄マウスモデルの脳低灌流を悪化させる2020
- Author(s)
  小林　果、森本　貴昭、原田　浩二、奥田　裕子、 Shohab Youssefian、及川　伸二、村田　真理子、小泉　昭夫
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213のユビキチンリガーゼ活性の検討2019
- Author(s)
  武田美都里, 手塚徹, 金びん秀, 西出旭, 崔廷米, 原田浩二, 小泉昭夫, ショハブ・ユーセフィアン
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子RNF213の結合分子の同定2019
- Author(s)
  崔廷米, 井上令一, 武田美都里, 小林果, 手塚徹, 原田浩二, 小泉昭夫, Youssefian Shohab
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] Rnf213遺伝子改変マウスにおける免疫細胞・血清サイトカインの系統的解析2019
- Author(s)
  小林果, 西村泰光, 奥田裕子, 原田浩二, 加畑理咲子, 武田美都里, 崔廷米, Youssefian Shohab, 大槻剛巳, 小泉昭夫
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] mysterin 遺伝子の肺高血圧症患者遺伝子スクリーニングおよびマウスモデルによる解析2018
- Author(s)
  小林果、加畑理咲子、木下秀之、森本貴昭、武田美都里、崔廷米、奥田裕子、原田浩二、Youssefian　Shohab、小泉昭夫
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] The Prevalence of RNF213 p.R4810K Variant is High in Juvenile-Onset Stroke Patients With Intracranial Arterial Stenosis2018
- Author(s)
  Teppei Kamimura, Shuhei Okazaki, Takaaki Morimoto, Hatasu Kobayashi, Kouji Harada, Tsutomu Tomita, Aya Higashiyama, Jun C Takahashi, Jyoji Nakagawara, Kazunori Toyoda, Akio Koizumi, Masafumi Ihara
- Organizer
  International Stroke Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病タンパク質RNF213 のE3 ligase活性の機能的評価2018
- Author(s)
  武田美都里、キムミンソ、小林果、原田浩二、土生敏行、小泉昭夫、ユーセフィアン　ショハブ
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397

1. SANO Hiroshi (20178809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 小泉昭夫 (50124574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. 手塚徹 (50312319)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 小林果 (70542091)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. 原田浩二 (80452340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. 土生敏行 (70346071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 高橋勉 (20270845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 奥田裕子 (30709663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 尾野恭一 (70185635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kim Minsoo (50466835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 水島恒裕 (90362269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IIDA Hidehiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. SAITO Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. MORIMOTO takaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. MIYAMOTO susumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. KINOSHITA Hideyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. CHOI JUNGMI

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 猪原匡史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 高橋淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 高木康志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 峰晴陽平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 森泰生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 岡崎周平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 平田真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shohab Youssefian Ｓ Ｙｏｕｓｓｅｆｉａｎ

S Youssefian ショハブ ユーセフィアン

ユセフィアン ショハブ ユセフィアン ショハブ

ユーセフィアン ショハブ ユーセフィアン ショハブ

YOUSSEFIAN Shohab ユ-セフィアン ショハブ

YOUSSEFIAN SHOHAB ユ-セフィアン ショハブ

SHOHAB YOUSSEFIAN

YOUSSEFIAN S. YOUSSEFIAN S

Research Projects

Research Products

Co-Researchers

もやもや病や脳梗塞の遺伝性リスク因子の機能解析Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular societyOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of mechanisms of pain evoked by meteorological environmentOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of a small GTP-binding Protein in Oxidative Stress-Induced Cell Death in PlantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of a plant gene encoding a small GTP-binding protein that is specifically induced by SO_2 and NO_2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

イオウを含む環境汚染物質の植物による浄化

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of plant expression by DNA methylation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFkB activation and apoptosis in an AAA+domain-dependent manne2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Moyamoya Disease and Spectrums of RNF213 Vasculopathy.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prevalence of RNF213 p.R4810K Variant in Early-Onset Stroke With Intracranial Arterial Stenosis2019

Shohab Youssefian ＳＹｏｕｓｓｅｆｉａｎ

S Youssefian ショハブユーセフィアン

ユセフィアンショハブユセフィアンショハブ

ユーセフィアンショハブユーセフィアンショハブ

YOUSSEFIAN Shohab ユ-セフィアンショハブ

YOUSSEFIAN SHOHAB ユ-セフィアンショハブ

[Presentation] もやもや病感受性遺伝子産物RNF213 の結合蛋白質の同定2020

[Presentation] RNF213 調節不全は両側総頸動脈狭窄マウスモデルの脳低灌流を悪化させる2020