ISHIBASHI Toshiyuki 石橋敏幸

… Alternative Names

石橋敏幸イシバシトシユキ

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Researcher Number	00223024
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2010 – 2011: 福島県立医科大学, 医学部, 博士研究員 2002 – 2004: Fukushima Medical University Depart. Of Medicine, Associate Professor, 医学部, 助教授 2001: 福島県立医科大学, 医学部, 講師 1997: 福島県立医科大学, 医学部, 講師 1996: 福島県立医科大学, 医学部, 助手 1991: 1st Dep. Int. Med. Fukushima Medical College, 第一内科, 助手
Review Section/Research Field	Principal Investigator Hematology / Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Hematology / Circulatory organs internal medicine
Keywords	Principal Investigator 血管内皮細胞 / RhoA / Rho / トロンボポエチン / endothelin / endothelial injury / coronary vasospasm / Coronary microcirculation / アセチルコリン / 攣縮 … More / ヘンドセリン / エンドセリン / 内皮損傷 / 冠攣縮 / 冠微小循環 / statins / geranylgeranylation / lipid modification / nonselective cation current / Reactive oxygen species / Calcium / Endothelial cells / HMG-CoA還元酵素阻害薬 / リゾフォスファチジルコリン / パッチクランプ / 膜電流 / H_2O_2 / スタチン / ゲラニルゲラニル化 / 脂質修飾 / 非選択的カチオン電流 / 活性酸素種 / カルシウム / 一酸化窒素合成酵素 / 一酸化窒素 / トロンボポエチン受容体 / 血管平滑筋細胞 … More Except Principal Investigator RhoA / calcium / NF-κB / plasminogen activator inhibitor-1 / tissue factor / oxidized LDL / monocyteadhesion / geranylgeranylation / endothelial dysfunction / 血管内皮細胞 / 組織因子 / 活性酸素種 / 酸化LDL / eNOS / カルシウム / NF-kB / PAI-1 / ゲラニルゲラニル化 / 単球 / 血管内皮細胞機能不全 / thrombopoietin / thrombocytopoiesis / megakaryocytopoiesis / cytokines / Interleukin 6 / Thrombopoietic factor / 巨核球 / 血小板造血 / Interleukinー6 / 血小板産産 / トロンボポエチン / 血小板産生 / 巨核球造血 / サイトカイン / インタ-ロイキン6 / 心不全 / 不整脈 / 移植・再生医療 / 再生医療 / 致死性不整脈 Less

Efficacy of Auto-PBACT combined with ICD implantation in cardiac anyloidosis
- Principal Investigator
  
  OGAWA Kazuei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukushima Medical University
Pathophysiology and therapeutic strategy of coronary vasospasm of microvessels using a novel porcine model.Principal Investigator
- Principal Investigator
  
  ISHIBASHI Toshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukushima Medical University
Signaling pathway and therapeutic strategy of endothelial dysfunction : role of small GTP-binding protein RhoA and beneficial effects of HMG-CoA reductase inhibitor
- Principal Investigator
  
  MARUYAMA Yukio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukushima Medical University
Role of Ca^<2+> signaling and reactive oxygen species in endothelial dysfunction induced by lysophosphatidylcholinePrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukushima Medical University
トロンボポエチンの血管内皮細胞におけるNO産生能に及ぼす影響と血小板凝集抑制Principal Investigator
- Principal Investigator
  
  石橋敏幸
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Fukushima Medical University
トロンボポエチンの血管内皮細胞および血管平滑筋細胞に及ぼす作用Principal Investigator
- Principal Investigator
  
  石橋敏幸
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukushima Medical University
The study on thrombopoietic activity of interleukin 6
- Principal Investigator
  
  KIMURA Hideo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Fukushima Medical College

All 2005 2004

All Journal Article Book

[Book] 炎症反応(p.118-119)酸化ストレスナビゲーター2005
- Author(s)
  石橋敏夫
- Total Pages
  329
- Publisher
  メディカルレビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Book] 炎症反応酸化ストレスナビゲータ2005
- Author(s)
  石橋敏幸
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essenttial process for RhoA activation in endothelial cells2005
- Author(s)
  Ohkawara H, Ishibashi T, et al.
- Journal Title
  
  Journal of Biological Chemistry 280(11)
  
  Pages: 10182-10188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] スタチンと凝固・線溶系2005
- Author(s)
  石橋敏夫
- Journal Title
  
  The Lipid 16(1)
  
  Pages: 41-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] スタチンと凝固・線溶系2005
- Author(s)
  石橋敏幸
- Journal Title
  
  The Lipid 16(1)
  
  Pages: 41-50
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells2005
- Author(s)
  Ohkawara H, Ishibashi T, et al.
- Journal Title
  
  Journal of Biological Chemistry 280(11)
  
  Pages: 10182-10188
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.2005
- Author(s)
  Hiroshi Ohkawara, Toshiyuki Ishibashi, Takayuki Sakamoto, Koichi Sugimoto, Kenji Nagata, Keiko Yokoyama, Nobuo Sakamoto, Masashi Kamioka, Isao Matsuoka, Shigetomo Fukuhara, Naotoshi Sugimoto, Yoh Takuwa, Yukio Maruyama.
- Journal Title
  
  Journal of Biological Chemistry 280 (11)
  
  Pages: 10182-10188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] Role of small GTP-binding proteins in endothelial dysfunction.2004
- Author(s)
  Toshiyuki Ishibashi, Yukio Maruyama.
- Journal Title
  
  Journal of Adaptation Medicine 8 (2)
  
  Pages: 23-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] 血管内皮機能不全における低分子GTP結合蛋白質の役割2004
- Author(s)
  石橋敏幸, 丸山幸夫
- Journal Title
  
  適応医学 8(2)
  
  Pages: 23-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] Repeated epicardial coronary artery endothelial injuries lead to a global spontaneous coronary artery spasm2004
- Author(s)
  Saitoh S, Ishibashi T, Maruyama Y, et al.
- Journal Title
  
  Coronary Artery Disease 15
  
  Pages: 137-145
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590762
[Journal Article] Repeated epicardial coronary artery endothelial injuries lead to a global spontaneous coronary artery spasm.2004
- Author(s)
  Shu-ichi Saitoh, Mitsuru Muto, Taku Osugi, Kazuhiko Aikawa, Ken Matsumoto, Futoshi Onogi, Kazuhira Maehara, Toshiyuki Ishibashi, Yukio Maruyama.
- Journal Title
  
  Coronary Artery Disease 15 (3)
  
  Pages: 137-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590762

1. MARUYAMA Yukio (90004712)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
2. OGAWA Kazuei (40423800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SUZUKI Hitoshi (10347213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKEISHI Yasuchika (40272067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKANO Masumi (60398344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIMURA Hideo (00128547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAITOH Shuichi (20274962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAOITA Hiroyuki (50264544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISHIBASHI Toshiyuki 石橋 敏幸

石橋 敏幸 イシバシ トシユキ

Research Projects

Research Products

Co-Researchers

Efficacy of Auto-PBACT combined with ICD implantation in cardiac anyloidosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiology and therapeutic strategy of coronary vasospasm of microvessels using a novel porcine model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Signaling pathway and therapeutic strategy of endothelial dysfunction : role of small GTP-binding protein RhoA and beneficial effects of HMG-CoA reductase inhibitor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Ca^<2+> signaling and reactive oxygen species in endothelial dysfunction induced by lysophosphatidylcholinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

トロンボポエチンの血管内皮細胞におけるNO産生能に及ぼす影響と血小板凝集抑制Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

トロンボポエチンの血管内皮細胞および血管平滑筋細胞に及ぼす作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study on thrombopoietic activity of interleukin 6

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 炎症反応(p.118-119)酸化ストレスナビゲーター2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 炎症反応 酸化ストレスナビゲータ2005

Author(s)

Publisher

Data Source

[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essenttial process for RhoA activation in endothelial cells2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] スタチンと凝固・線溶系2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] スタチンと凝固・線溶系2005

Author(s)

Journal Title

Data Source

[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells2005

Author(s)

Journal Title

Data Source

[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.2005

Author(s)

Journal Title

Description

Data Source

ISHIBASHI Toshiyuki 石橋敏幸

石橋敏幸イシバシトシユキ

[Book] 炎症反応酸化ストレスナビゲータ2005