sakurai hiroshi 桜井博

… Alternative Names

Sakurai Hiroshi 桜井博

SAKURAI Hiroshi 桜井博

櫻井博サクライヒロシ

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Researcher Number	00225848
Other IDs
Affiliation (Current)	2025: 金沢大学, 保健学系, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 金沢大学, 保健学系, 教授 2008 – 2011: Kanazawa University, 保健学系, 准教授 2008: Kanazawa University, 保健学系, 準教授 2007: Kanazawa University, 医学系研究科, 准教授 2005 – 2006: 金沢大学, 医学系研究科, 助教授 … More 1998 – 2004: 金沢大学, 医学部, 助教授 1999: 金沢大学, 医学部, 教授 1996 – 1997: 金沢大学, 医学部, 講師 1995: Keio University School of Medicine, 医学部, 助手 1994 – 1995: 慶應義塾大学, 医学部, 助手 1994: 慶應義塾大学, 医学部分子遺伝学, 助手 Less
Review Section/Research Field	Principal Investigator Molecular biology / Molecular biology / Basic Section 44010:Cell biology-related / Functional biochemistry Except Principal Investigator General medical chemistry / Basic Section 59040:Nutrition science and health science-related / Basic Section 43020:Structural biochemistry-related
Keywords	Principal Investigator 酵母 / 基本転写因子 / 転写制御 / 熱ショック転写因子 / ストレス応答 / 酵母菌 / Protein phosphatase 2A / プロテインホスファターゼ / yeast / phosphorylation … More / stress response / リン酸化 / 培養細胞 / 転写開始点 / 転写調節因子E2F / Rbがん抑制タンパク / サイクリン / IER2タンパク / Rbがん抑制遺伝子 / 細胞運動 / 細胞周期 / E2F転写調節因子 / RBがん抑制遺伝子 / IERタンパク / PP2Aアダプタータンパク / ストレス / 蛋白質 / 遺伝子 / タンパク分解 / 転写開始と伸長 / MAPキナーゼ / GADD45 / CDC25 / HSF1 / IER5L / IER5 / IER2 / 熱ショック応答 / 初期応答遺伝子 / MAPキナーゼ経路 / 細胞増殖 / heat shock transcription factor / heat shock factor / 抑圧変異 / 転写開始 / 熱ショック遺伝子 / 転写因子 / 遺伝子特異性 / 基礎転写 … More Except Principal Investigator 芳香族アミノ酸 / 紫外共鳴ラマン / ヘモグロビン / SH3 / UV resonance Raman / 異常血色素 / トリプトファン / チロシン / 円二色性 / 四次構造変化 / T状態マーカー / 近紫外円二色性 / 4次構造変化 / アロステリー / ガラクトース / 非アルコール性脂肪肝炎（NASH） / 非アルコール性脂肪肝炎 / 転写因子 / 運動 / 腸管透過性 / マクロファージ / 非アルコール性脂肪肝炎(NASH) / Heat shock protein / HSP / アミロイドβ / ミスフォールディング / アミロイド / 熱ショックタンパク質 / うつ様行動 / マウス / 社会敗北ストレス / うつ病 / quaternary structure transition / tryptophan / tyrosine / mutants / near-UV CD / hemoglobin / 共鳴ラマン分光 / SrcSH3 domein / PI3K / 円二色性(CD) / 蛋白質の機能 / アロステリックエフェクター / HbM / 共鳴ラマン / CD / 酸素結合機能 / 高次構造変化 / 変異体 / 近紫外域CD / Oxygen equilibrium / T-state marker / Aromatic amino acids / Ouaternary structure transition / Allostery / UVCD / Hemoglobin / 機能異常 / トリプトフン / タンパクの構造変化 / 酸素平衡機能 / 酵素平衡機能 / 紫外円二色性 / Saccharomyces cerevisiae / Phosphoryration / Basal factor / Basal transcription / Reconstitution System / Galactose / サッカロミセス属酵母 / 燐酸化 / 基本転写因子 / 基礎転写 / 再構成系 / 転写誘導 / 酵母 Less

運動と非アルコール性脂肪肝炎の改善をつなぐ制御分子機構の解明
- Principal Investigator
  
  永島田まゆみ
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa University
Regulation of signal transduction and cell growth by protein phosphatase 2APrincipal Investigator
- Principal Investigator
  
  Sakurai Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kanazawa University
Elucidation of the mechanism of depression development focusing on protein misfolding.
- Principal Investigator
  
  Hashikawa Naoya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Okayama University of Science
Involvement of non-chaperone target genes for heat shock transcription factor in cell homeostasis.Principal Investigator
- Principal Investigator
  
  Sakurai Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Gene-specific transcriptional regulation by heat shock factorPrincipal Investigator
- Principal Investigator
  
  SAKURAI Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
Recognition of diverse nucleotide sequences by heat shock transcription factors of various organismsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
Phosphorylation of heat shock transcription factor in the stress responsePrincipal Investigator
- Principal Investigator
  
  SAKURAI Hiroshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
Relation between the structure and function of proteins studied by the changes of tyrosine and tryptophan residues.
- Principal Investigator
  
  NAGAI Masako
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Hosei University
  Kanazawa University
Interaction between heat shock transcription factor and transcription initiation complex.Principal Investigator
- Principal Investigator
  
  SAKURAI Hiroshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
転写開始から伸長反応への移行における転写因子の作用機構Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
転写開始複合体を形成するタンパク質間の遺伝子特異的な相互作用Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
ヘモグロビンにおけるヘム鉄の蛋白質による機能制御
- Principal Investigator
  
  NAGAI Masako
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
転写調節因子およびプロモーター構造に特異的な転写開始機構Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
転写調節における基本転写因子とプロモーターの特異的相互作用Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
Relationship of function and higher order structure of abnormal hemoglobin.
- Principal Investigator
  
  NAGAI Masako
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
基本転写因子のプロモーター構造特異的な作用機構Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
酵母転写因子GAL11と基本因子TFIIEの相互作用Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
酵母GAL80遺伝子の転写開始点結合タンパク質の機能解析Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Keio University
酵母のガラクトース応答機構
- Principal Investigator
  
  FUKASAWA Toshio
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University
酵母転写因子GAL11と相互作用する基本因子の研究Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University
酵母GAL80遺伝子の転写開始点に依存した転写制御機構Principal Investigator
- Principal Investigator
  
  桜井博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Keio University
Structure and Function of Regulatory Circuit of Galactose-inducible Genes in Yeast
- Principal Investigator
  
  FUKASAWA Toshio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Keio University School of Medicine

[Journal Article] PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genes2023
- Author(s)
  Kuriko Doi, Hiroto Takeuchi, Hiroshi Sakurai
- Journal Title
  
  FEBS Journal
  
  Volume: 293 Issue: 3 Pages: 745-762
- DOI
  10.1111/febs.16612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06619
[Journal Article] Regulation of the stability and activity of CDC25A and CDC25B by protein phosphatase PP2A and 14-3-3 binding.2019
- Author(s)
  Kohama Y, Saito M, Yada M, Sakurai H.
- Journal Title
  
  Cellular Signalling
  
  Volume: 54 Pages: 10-16
- DOI
  10.1016/j.cellsig.2018.11.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07292
[Journal Article] IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A.2019
- Author(s)
  Ueda T, Kohama Y, Sakurai H.
- Journal Title
  
  Cellular Signalling
  
  Volume: 55 Pages: 81-89
- DOI
  10.1016/j.cellsig.2018.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07292
[Journal Article] TAF7 is a heat-inducible unstable protein and is required for sustained expression of heat shock protein genes2018
- Author(s)
  Nagashimada Mayumi、Ueda Takumi、Ishita Yuichiro、Sakurai Hiroshi
- Journal Title
  
  The FEBS Journal
  
  Volume: 285 Issue: 17 Pages: 3215-3224
- DOI
  10.1111/febs.14604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-16K07292
[Journal Article] GADD45 family proteins suppress JNK signaling by targeting MKK7.2017
- Author(s)
  Ueda T, Kohama Y, Kuge A, Kido E, Sakurai H.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 635 Pages: 1-7
- DOI
  10.1016/j.abb.2017.10.005
- NAID
  120006374147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07292
[Journal Article] Activation of ERK/IER3/PP2A-B56g positive feedback loop in lung adenocarcinoma by allelic deletion of B56g gene.2016
- Author(s)
  Ito T, Ozaki S, Chanasong R, Mizutani Y, Oyama T, Sakurai H, Matsumoto I, Takemura H, Kawahara E.
- Journal Title
  
  Oncology Reports
  
  Volume: 35 Issue: 5 Pages: 2635-2642
- DOI
  10.3892/or.2016.4677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07292, KAKENHI-PROJECT-16K08687
[Journal Article] Heme Orientation of Cavity Mutant Hemoglobins (His F8 --> Gly) in Either alpha or beta Subunits: Circular Dichroism, (1) H NMR, and Resonance Raman Studies.2016
- Author(s)
  Nagai, M., Nagai, Y., Aki, Y., Sakurai, H., Mizusawa, N., Ogura, T., Kitagawa, T., Yamamoto, Y. and Nagatomo, S.
- Journal Title
  
  Chirality
  
  Volume: 28 Issue: 8 Pages: 585-592
- DOI
  10.1002/chir.22620
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00960, KAKENHI-PROJECT-16K07292
[Journal Article] Diversity in DNA recognition by heat shock transcription factors(HSFs) from model organisms2011
- Author(s)
  Enoki, Y., Sakurai, H.
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Pages: 1293-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Regulation of chaperone gene expression by heat shock transcription factor in Saccharomyces cerevisiae2011
- Author(s)
  Sakurai, H.
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Issue: 17 Pages: 2744-2748
- DOI
  10.1016/j.febslet.2011.07.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Regulation of chaperone gene expression by heat shock transcription factor in Saccharomyces cerevisiae : Importance in normal cell growth, stress resistance and longevity2011
- Author(s)
  Sakurai, H., Ota, A.
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Pages: 2744-2748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Binding affinities and interactions among different heat shock element types and heat shock factors in rice(Oryza sativa L.)2011
- Author(s)
  Mittal, DJ., Enoki, Y., Lavania, D., Singh, A., Sakurai, H., Grover, A.
- Journal Title
  
  FEBS Journal
  
  Volume: 278 Pages: 3076-3085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] DNA-binding and transcriptional activities of human HSF4 containing mutations that associate with congenital and age-related cataracts2010
- Author(s)
  Enoki, Y., Mukoda, Y., Furutani, C., Sakurai, H.
- Journal Title
  
  Biochimica et Biophysica Acta Molecular Basis of Disease
  
  Volume: 1802 Pages: 749-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Novel aspects of heat shock factors : DNA recognition, chromatin modulation and gene expression2010
- Author(s)
  Sakurai, H., Enoki, Y.
- Journal Title
  
  FEBS Journal
  
  Volume: 277 Pages: 4140-4149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Mutational analysis of human heat-shock transcription factor 1 reveals a regulatory role for oligomerization in DNA-binding specificity2009
- Author(s)
  Takemori, Y., Enoki, Y., Yamamoto, N., Fukai, Y., Adachi, K., Sakurai, H.
- Journal Title
  
  Biochemical Journal
  
  Volume: 424 Pages: 253-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Galactose transporters discriminate steric anomers at the cell surface in yeast2009
- Author(s)
  Fukasawa, T., Sakurai, H., Nogi, Y., Baruffini, E.
- Journal Title
  
  FEMS Yeast Research
  
  Volume: 9 Pages: 723-731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570181
[Journal Article] Differential recognition of heat shock elements by members of the heat shock transcription factor family2009
- Author(s)
  Noritaka Yamamoto, Yukiko Takemori, Mayumi Sakurai, Kazuhisa Sugiyama, and Hiroshi Sakurai
- Journal Title
  
  FEBS Journal 276
  
  Pages: 1962-1974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] (2008)Regulation of thermotolerance by stress-induced transcription factors in Saccharomyces cerevisiae2008
- Author(s)
  Noritaka Yamamoto, Yuka Maeda, Aya Ikeda, and Hiroshi Sakurai
- Journal Title
  
  Eukaryotic Cell 7
  
  Pages: 783-790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] resistance and TOR signaling in Yeast revealed by combined proteomic and genetic analysis2008
- Author(s)
  Sricharan Bandhakavi, Hongwei Xie, Brennon O'Callaghan, Hiroshi Sakurai, Do-Hyung Kim, Timothy and J. Griffin
- Journal Title
  
  PLoS One 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] Interaction between heat shock transcription factors (HSFs) and divergent binding sequences.2007
- Author(s)
  Sakurai, H, Takemori, Y.
- Journal Title
  
  Journal of Biological Chemistry 282(印刷中)
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Role of heat shock transcription factor in the Saccharomyces cerevisiae oxidative stress response2007
- Author(s)
  Ayako Yamamoto, Junko Ueda, Noritaka Yamamoto, Naoya Hashikawa, and Hiroshi Sakurai
- Journal Title
  
  Eukaryotic Cell 6
  
  Pages: 1373-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] Different mechanisms are involved in the transcriptional activation by heat shock transcription factor through different typesof heat shock elements2007
- Author(s)
  Naoya Hashikawa, Noritaka Yanamoto and Hiroshi Sakurai
- Journal Title
  
  Journal of Biological Chememistry 282
  
  Pages: 10333-10340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] Interaction between heat shock transcription factors (HSFs) and divergent binding sequences : binding specificities of yeast HSFs and human HSF12007
- Author(s)
  Hiroshi Sakurai and Yukiko Takemori
- Journal Title
  
  Journal of Biological Chememistry 282
  
  Pages: 13334-13341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] Interaction between heat shock transcription factors(HSFs) and divergent binding sequences: binding specificities of yeast HSFs and human HSF12007
- Author(s)
  Sakurai, H., et. al.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 13334-13341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570164
[Journal Article] Different mechanisms are involved in the transcriptional activation by heat shock transcription factor through different types of heat shock elements2007
- Author(s)
  Naoya Hashikawa, Noritaka, Yamamoto, Hiroshi Sakurai
- Journal Title
  
  Journal of Biological Chemistry 282・14
  
  Pages: 10333-10340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Interaction between heat shock transcription factors (HSFs) and divergent binding sequences.2007
- Author(s)
  Sakurai, H., Takemori, Y.
- Journal Title
  
  Journal of Biological Chemistry 282・18
  
  Pages: 13334-13341
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Interaction between heat shock transcription factors (HSFs) and divergent binding sequences2007
- Author(s)
  Hiroshi Sakurai, Yukiko Takemori
- Journal Title
  
  Journal of Biological Chemistry 282・18
  
  Pages: 13334-13341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] The DNA-binding domain of yeast Hsfl regulates both DNA binding and transcriptional activities.2006
- Author(s)
  Yamamoto, A., Sakurai H.
- Journal Title
  
  Biochemical and Biophysical Research Communications 346・4
  
  Pages: 1324-1329
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Mutated yeast heat shock transcription factor activates transcription independently of hyperphosphorylation2006
- Author(s)
  Naoya Hashikawa, Yu Mizukami, Hiromi Imazu, Hiroshi Sakurai
- Journal Title
  
  Journal of Biological Chemistry 281・7
  
  Pages: 3936-3942
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] The DNA-binding domain of yeast Hsf1 regulates both DNA binding and transcriptional activities.2006
- Author(s)
  Yamamoto, A., Sakurai H.
- Journal Title
  
  Biochemical and Biophysical Research Communications 346・4
  
  Pages: 1324-1329
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Stress-induced transcription of the endoplasmic reticulum oxidoreductin gene ERO1 in the yeast Saccharomyces cerevisiae2006
- Author(s)
  Yukiko Takemori, Ayako Sakaguchi, Saori, Matsuda, Yu Mizukami, Hiroshi Sakurai
- Journal Title
  
  Molecular Genetics and Genomics 275・1
  
  Pages: 89-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] The DNA-binding domain of yeast Hsfl regulates both DNA binding and transcriptional activities2006
- Author(s)
  Ayako Yamamoto, Hiroshi Sakurai
- Journal Title
  
  Biochemical and Biophysical Research Communications 346・4
  
  Pages: 1324-1329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Regulation of stress response by heat shock transcription factor2005
- Author(s)
  Hiroshi Sakurai
- Journal Title
  
  Seikagaku 77・4
  
  Pages: 347-350
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock2005
- Author(s)
  Hiromi Imazu, Hiroshi Sakurai
- Journal Title
  
  Eukaryotic Cell 4・6
  
  Pages: 1050-1056
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] 熱ショック転写因子によるストレス応答の制御2005
- Author(s)
  桜井博
- Journal Title
  
  生化学 77・4
  
  Pages: 347-350
- NAID
  10015548526
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] 熱ショック転写因子によるストレス応答の制御2005
- Author(s)
  桜井博
- Journal Title
  
  「生化学」日本生化学会 (印刷中)
- NAID
  10015548526
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in Saccharomyces cerevisiae2005
- Author(s)
  Ayako Yamamoto, Yu Mizukami, Hiroshi Sakurai
- Journal Title
  
  Journal of Biological Chemistry 280・12
  
  Pages: 11911-11919
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Changes of near-UV CD spectrum of human hemoglobin upon oxygen binding : A study of mutants at α42,α140,β145Tyr and β37 Trp..2004
- Author(s)
  Jin, Y., Sakurai, H., Nagai, Y., Nagai, M.
- Journal Title
  
  Biopolymers 74
  
  Pages: 60-63
- Data Source
  KAKENHI-PROJECT-14570103
[Journal Article] Changes of near-UV CD spectrum of human hemoglobin upon oxygen binding : A study of mutants at α42,α140,β145 tyrosine or β37 tryptophan.2004
- Author(s)
  Jin, Y., Sakurai, H., Nagai, Y., Nagai, M.
- Journal Title
  
  Biopolymers 74
  
  Pages: 60-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570103
[Journal Article] Phosphorylation of the yeast heat shock transcription factor is implicated in gene-specific activation dependent on the architecture of the heat shock element2004
- Author(s)
  Hashikawa, N., Sakurai, H.
- Journal Title
  
  Molecular and Cellular Biology 24・9
  
  Pages: 3648-3659
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Phosphorylation of the yeast heat shock transcription factor is implicated in genespecific activation dependent on the architecture of the heat shock element2004
- Author(s)
  N.Hashikawa, H.Sakurai
- Journal Title
  
  Molecular and Cellular Biology 24・9
  
  Pages: 3648-3659
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Phosphorylation of the yeast heat shock transcription factor is implicated in gene-specific activation dependent on the architecture of the heat shock element2004
- Author(s)
  Naoya Hashikawa, Hiroshi Sakurai
- Journal Title
  
  Molecular and Cellular Biology 24・9
  
  Pages: 3648-3659
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570142
[Journal Article] Changes of near-UV CD spectrum of human hemoglobin upon oxygen binding : A study of mutants at α42, α140, β145 Tyr or β37 Trp.2004
- Author(s)
  Jin, Y., Sakurai, H., Nagai, Y., Nagai, M.
- Journal Title
  
  Biopolymers 74
  
  Pages: 60-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570103
[Presentation] 転写調節因子E2F1のリン酸化による機能制御2022
- Author(s)
  竹内寛人、古賀麻佑子、小林ななみ、土居久里子、櫻井博
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06619
[Presentation] Protein phosphatase PP2AアダプタータンパクによるRbのリン酸化と活性の制御2021
- Author(s)
  土居久里子、櫻井博
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06619
[Presentation] プロテインホスファターゼ2Aとアダプタータンパクによる細胞周期遺伝子の調節2020
- Author(s)
  櫻井博、辻琴羽、土居久里子
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06619
[Presentation] 14-3-3タンパクによるCDC25の安定性と活性調節2018
- Author(s)
  小濱祐里、齋藤愛望、矢田瑞恵、櫻井博
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07292
[Presentation] 初期応答遺伝子IERタンパク質群によるprotein phosphatase 2A活性の制御2017
- Author(s)
  上田拓実、小濱祐里、桜井博
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07292
[Presentation] プロテインホスファターゼPP2A/調節タンパクIER5によるCDC25Bの活性調節2017
- Author(s)
  小濱祐里、上田拓実、桜井博
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07292
[Presentation] DNA損傷誘導性タンパクGADD45による熱ショック応答とMAPキナーゼの制御2016
- Author(s)
  上田拓実、小濱祐里、久下綾菜、城戸恵梨子、太田あづ美、桜井博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07292
[Presentation] 酵母Hsf1によるシャペロン遺伝子の発現調節:細胞増殖、ストレス抵抗性、寿命における重要性2011
- Author(s)
  桜井博,太田あづ美
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21570181
[Presentation] 酵母Hsf1によるシャペロン遺伝子の発現調節2011
- Author(s)
  桜井博
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21570181
[Presentation] 熱ショック転写因子HSF1のDNA結合調節2010
- Author(s)
  榎康明,桜井博
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21570181
[Presentation] さまざまな生物の熱ショック転写因子の機能解析2009
- Author(s)
  榎康明,向田裕香,古谷智慧,桜井博
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21570181
[Presentation] 金属誘導型転写因子タンパク質の設計2008
- Author(s)
  菅原大, 舟越靖, 山本慶隆, 桜井博, 山上健, 石野良純, 田中俊樹
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-19570164
[Presentation] 熱ショック転写因子ファミリーの異なったDNA塩基配列認識2008
- Author(s)
  山本慶隆, 竹森優喜子, 榎康明, 桜井博
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570164
[Presentation] 酵母熱ショック転写因子(Hsfl)による遺伝子特異的なメデイェータ-のリクルートメント2008
- Author(s)
  橋川直也, 桜井博
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570164
[Presentation] 酵母熱ショック転写因子(Hsf1)による遺伝子特異的なメディエーターのリクルートメント2008
- Author(s)
  橋川直也, 桜井博
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570164
[Presentation] 金属イオン誘導性人工転写因子の設計と構築2008
- Author(s)
  村瀬茂雄, 舟越靖, 山上健, 石野良純, 山本慶隆, 桜井博, 田中俊樹
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570164
[Presentation] ヒト熱ショック転写因子による結合配列特異的な転写調節2007
- Author(s)
  山本慶隆, 池田彩, 前田夕佳, 竹森優喜子, 桜井博
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19570164

1. FUKASAWA Toshio (90029934)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NAGAI Masako (60019578)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. SUZUKI Yuriko (40255435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WADA Tadashi (60262309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HANDA Hiroshi (80107432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IMAI Kiyohiro (50028528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Hashikawa Naoya (60434982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福間真理子 (60101995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 置塩信行 (20262561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 荒磯裕平 (20753726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 永島田まゆみ (30645510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 本多政夫 (00272980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. LORCH Yahli

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. JOHNSTON Stephen a

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KORNBERG Roger d

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. BERK A.J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小倉尚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sakurai hiroshi 桜井 博

Sakurai Hiroshi 桜井 博

SAKURAI Hiroshi 桜井 博

櫻井 博 サクライ ヒロシ

Research Projects

Research Products

Co-Researchers

運動と非アルコール性脂肪肝炎の改善をつなぐ制御分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of signal transduction and cell growth by protein phosphatase 2APrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of depression development focusing on protein misfolding.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of non-chaperone target genes for heat shock transcription factor in cell homeostasis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene-specific transcriptional regulation by heat shock factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Recognition of diverse nucleotide sequences by heat shock transcription factors of various organismsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Phosphorylation of heat shock transcription factor in the stress responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relation between the structure and function of proteins studied by the changes of tyrosine and tryptophan residues.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction between heat shock transcription factor and transcription initiation complex.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写開始から伸長反応への移行における転写因子の作用機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写開始複合体を形成するタンパク質間の遺伝子特異的な相互作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ヘモグロビンにおけるヘム鉄の蛋白質による機能制御

Principal Investigator

Project Period (FY)

Research Category

Research Institution

転写調節因子およびプロモーター構造に特異的な転写開始機構Principal Investigator

Principal Investigator

Project Period (FY)

sakurai hiroshi 桜井博

Sakurai Hiroshi 桜井博

SAKURAI Hiroshi 桜井博

櫻井博サクライヒロシ