INOUE Nagamu 井上詠

Researcher Number	00232546
Other IDs
Affiliation *help	2014 – 2015 : 慶應義塾大学, 医学部, 准教授 2007 – 2011 : Keio University, School of Medicine, Assistant Professor 2008 – 2009 : 慶應大, 医学部, 講師 2003 – 2007 : 慶應大, 医学部, 助手 2003 – 2006 : 慶應義塾大学, 医学部, 助手 … More
Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 炎症性腸疾患 / クローン病 / 腸内細菌 / 潰瘍性大腸炎 / 自然免疫 / intestinal microflora / マクロファージ / 細胞内寄生菌 / Crohn's disease / モデルマウス … More Except Principal Investigator 大腸癌 / dysplasia / サーベイランス / 潰瘍性大腸炎 / ELISA / p53 / 内視鏡 / 早期発見 / 内神鏡 / 清瘍性大腸炎 Less

重症潰瘍性大腸炎に対する治療戦略-組織標的プロテオミクス解析による治療効果予測Principal InvestigatorOngoing
- Principal Investigator
  
  井上詠
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Importance of dysregulated autophagy to intracellular parasiting bacteria in the pathogenesis of Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Elucidation of intestinal mucosal immune system through the intracellular processing mechanisms of bacteria and its application for novel therapy of inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Institution
  Keio University
Establishment of cancer surveillance using serum anti-p53 antibody in patients with ulcerative colitis
- Principal Investigator
  
  IWAO Yasushi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
潰瘍性大腸炎合併大腸癌に対する新しいサーベイランス法の確立-抗p53抗体の有用性
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Involvement of intestinal flora in the pathogenesis of chronic'colitisPrincipal Investigator
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of novel mouse model of human Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
免疫グロブリン可変領域遺伝子よりみた潰瘍性大腸炎病変粘膜内自己抗体産生細胞の特性Principal Investigator
- Principal Investigator
  
  井上詠
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Dental College
クローン病類似大腸炎モデルの作製と_<rs>CD4による新たな治療法の開発Principal Investigator
- Principal Investigator
  
  井上詠
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
クローン病の大腸炎症局所湿潤T細胞の抗原受容体β鎖可変領域遺伝子再構成の検討Principal Investigator
- Principal Investigator
  
  井上詠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University

All 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Adalimumab for the treatment of Japanese patients with intestinal Behçet's disease.2015
- Author(s)
  Tanida S, Inoue N, Kobayashi K, Naganuma M, Hirai F, Iizuka B, Watanabe K, Mitsuyama K, Inoue T, Ishigatsubo Y, Suzuki Y, Nagahori M, Motoya S, Nakamura S, Arora V, Robinson AM, Thakkar RB, Hibi T.
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume : 13 Pages : 940-948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460964, KAKENHI-PROJECT-26460977
[Journal Article] Risk factors for decreased bone mineral density in inflammatory bowel disease: A cross-sectional study.2015
- Author(s)
  Wada Y, Hisamatsu T, Naganuma M, Matsuoka K, Okamoto S, Inoue N, Yajima T, Kouyama K, Iwao Y, Ogata H, Hibi T, Abe T, Kanai T
- Journal Title
  
  Clin Nutr
  
  Volume : 34 Pages : 1202-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-26460977
[Journal Article] Risk and Management of Intra-Abdominal Abscess in Crohn's Disease Treated with Infliximab2014
- Author(s)
  Yoneno K, Hisamatsu T, Matsuoka K, Okamoto S, Takayama T, Ichikawa R, Sujino T, Miyoshi J, Takabayashi K, Mikami Y, Mizuno S, Wada Y, Yajima T, Naganuma M, Inoue N, Iwao Y, Ogata H, Hasegawa H, Kitagawa Y, Hibi T, Kanai T
- Journal Title
  
  Digestion
  
  Volume : 89 Pages : 201-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460977, KAKENHI-PROJECT-12J05920
[Journal Article] Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease2012
- Author(s)
  Hisamatsu T, Inoue N, et al
- Journal Title
  
  PLoS One
  
  Volume : 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease2012
- Author(s)
  Hisamatsu T, Okamoto S, Hashimoto M, Muramatsu T, Andou A, Uo M, Kitazume MT, Matsuoka K, Yajima T, Inoue N, Kanai T, Ogata H, Iwao Y, Yamakado M, Sakai R, Ono N, Ando T, Suzuki M, Hibi T
- Journal Title
  
  PLoS One
  
  Volume : 7(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease2011
- Author(s)
  Miyoshi J, Inoue N, et al
- Journal Title
  
  J Gastroenterol
  
  Volume : 46 Pages : 1056-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease2011
- Author(s)
  Miyoshi J, Yajima T, Okamoto S, Matsuoka K, Inoue N, Hisamatsu T, Shimamura K, Nakazawa A, Kanai T, Ogata H, Iwao Y, Mukai M, Hibi T
- Journal Title
  
  J Gastroenterol
  
  Volume : 46(9) Pages : 1056-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] Target biopsy or step biopsy? Optimal surveillance for ulcerative colitis : a Japanese nationwide randomized controlled trial.2011
- Author(s)
  Watanabe T, Ajioka Y, Matsumoto T, Tomotsugu N, Takebayashi T, Inoue E, Iizuka B, Igarashi M, Iwao Y, Ohtsuka K, Kudo SE, Kobayashi K, Sada M, Matsumoto T, Hirata I, Murakami K, Nagahori M, Watanabe K, Hida N, Ueno F, Tanaka S, Watanabe M, Hibi T
- Journal Title
  
  J Gastroenterol 46Suppl 1
  
  Pages : 11-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] 消化器疾患と樹状細胞病態の解明と治療法の開発クローン病におけるCD14+腸管マクロファージの抗原提示能について2010
- Author(s)
  久松理一、井上詠, 他
- Journal Title
  
  消化器と免疫
  
  Volume : 46 Pages : 36-38
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T
- Journal Title
  
  Eur J Immunol
  
  Volume : 40(9) Pages : 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] 消化器疾患と樹状細胞病態の解明と治療法の開発クローン病におけるCD14+腸管マクロファージの抗原提示能について2010
- Author(s)
  久松理一、井上詠, 他
- Journal Title
  
  消化器と免疫
  
  Volume : 46 Pages : 36-38
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Inoue N, et al
- Journal Title
  
  Eur J Immunol
  
  Volume : 40 Pages : 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T
- Journal Title
  
  Eur J Immunol 40(9)
  
  Pages : 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis.2010
- Author(s)
  Kobayashi T, Naganuma M, Okamoto S, Hisamatsu T, Inoue N, Ichikawa H, Takayama T, Saito R, Sujino T, Ogata H, Iwao Y, Hibi T
- Journal Title
  
  J Gastroenterol 45(11)
  
  Pages : 1129-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] Novel endoscopic activity index is useful for choosing treatment in severe active ulcerative colitis patients.2010
- Author(s)
  Naganuma M, Ichikawa H, Inoue N, Kobayashi T, Okamoto S, Hisamatsu T, Kanai T, Ogata H, Iwao Y, Hibi T
- Journal Title
  
  J Gastroenterol 45(9)
  
  Pages : 936-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] クローン病における腸管マクロファージの腸内細菌認識異常 IL-23を中心とした慢性炎症サイクル2009
- Author(s)
  久松理一, 井上詠, 他
- Journal Title
  
  消化器と免疫 45
  
  Pages : 52-54
- Data Source
  KAKENHI-PROJECT-21590820
[Journal Article] クローン病における腸管マクロファージの腸内細菌認識異常IL-23を中心とした慢性炎症サイクル2009
- Author(s)
  久松理一、井上詠, 他
- Journal Title
  
  消化器と免疫 45
  
  Pages : 52-54
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease2008
- Author(s)
  Takaishi, H, Inoue, N, Hib, i T, et. al.
- Journal Title
  
  Int J Med Microbiol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells2008
- Author(s)
  Kamada, N, Inoue, N, Hibi, T, et. al.
- Journal Title
  
  Infect Immun 76(1)
  
  Pages : 214-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transd uction in intestinal epithelial cells2008
- Author(s)
  Kamada N, Inoue N, Hibi T, et. al.
- Journal Title
  
  Infect Immun 76
  
  Pages : 214-220
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease2008
- Author(s)
  Takaishi H, Inoue N, Hibi T, et. al.
- Journal Title
  
  Int J Med Microbiol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coh strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells2008
- Author(s)
  Kamada N, Inoue N, Hibi T, et. al.
- Journal Title
  
  Infect Immun 76
  
  Pages : 214-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice2008
- Author(s)
  Nanno M, Inoue N, Hibi T, et. al.
- Journal Title
  
  Gastroenterology 134
  
  Pages : 481-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Imbalance in intesthlal microf[ora constitution could be ivolved in thepathogenesis of inflammatory bowel disease2008
- Author(s)
  Takaishi H, Inoue N, Hibi, T, et. al.
- Journal Title
  
  Int J Med Microbiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Exacerbating role of gammadelta T-cells in chronic colitis of T-cell receptoralpha mutant mice2008
- Author(s)
  Nanno M, Inoue N, et.al.
- Journal Title
  
  Gastroenterology 134
  
  Pages : 481-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease.2008
- Author(s)
  Takaishi H, Matsuki T, Nakazawa A, Takada T, Kado S, Asahara T, Kamada N, Sakuraba A, Yajima T, Higuchi H, Inoue N, Ogata H, Iwao Y, Nomoto K, Tanaka R, Hibi T
- Journal Title
  
  Int J Med Microbiol 298(5-6)
  
  Pages : 463-472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.2008
- Author(s)
  Nanno M, Kanari Y, Naito T, Inoue N, Hisamatsu T, Chinen H, Sugimoto K, Shimomura Y, Yamagishi H, Shiohara T, Ueha S, Matsushima K, Suematsu M, Mizoguchi A, Hibi T, Bhan AK, Ishikawa
- Journal Title
  
  Gastroenterology 134(2)
  
  Pages : 481-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Non-pathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells.2008
- Author(s)
  Kamada N, Maeda K, Inoue N, Hisamatsu T, Okamoto S, Hong KS, Yamada T, Watanabe N, Tsuchimoto K, Ogata H, Hibi T
- Journal Title
  
  Infect Immun 76(1)
  
  Pages : 214-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007
- Author(s)
  Yoshizawa S, Inoue N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007
- Author(s)
  Matsuoka K, Inoue N, Hibi T et al.
- Journal Title
  
  Am J Gastroenterol (in press)
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007
- Author(s)
  Matsuoka K, Iwao Y, Inoue N, Hibi T et al.
- Journal Title
  
  Am J Gastroenterol (in press)
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007
- Author(s)
  Yoshizawa S, Inoue N, Iwao Y, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Nonpathogenic Escherichia coil strain Nissle1917 prevents murine acute and chronic colitis2006
- Author(s)
  Kamada N, Inoue N, Hibi T, et. al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages : 455-463
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis2006
- Author(s)
  Kamada, N, Inoue, N, Hibi, T, et. al.
- Journal Title
  
  Inflamm Bowel Dis 11(5)
  
  Pages : 455-463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Inoue N, Hibi T et al.
- Journal Title
  
  J Gastroenterol 41・4
  
  Pages : 318-324
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coli strain Nisslel917 prevents murine acute and chronic colitis.2006
- Author(s)
  Kamada N, Inoue N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages : 455-463
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Inoue N, Iwao Y, Hibi T et al.
- Journal Title
  
  J Gastroenterol Apr.41(4)
  
  Pages : 318-324
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara T, Inoue N, Hibi T et al.
- Journal Title
  
  J Gastroenterol Hepatol 20・5
  
  Pages : 710-715
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005
- Author(s)
  Hitotsumatsu O, Inoue N, Hibi T, Ishikawa H et al.
- Journal Title
  
  J Gastroenterol 40・10
  
  Pages : 956-963
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N, Inoue N, Hibi T et al.
- Journal Title
  
  J Immunol 175・10
  
  Pages : 6900-6908
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Non-pathogenic Escherichia coil strain Nissle 1917 prevents murine acute and chronic colitis.2005
- Author(s)
  Kamada N, Inoue N, et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara T, Inoue N, et al.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Non-pathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis.2005
- Author(s)
  Kamada N, Inoue N, et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, et al.
- Journal Title
  
  GUT 53
  
  Pages : 1303-1308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Granulocytapheresis is useful as an alterative therapy in patients with steroid-refractory or-dependent ulcerative colitis.2004
- Author(s)
  Naganuma M, Inoue N, et al.
- Journal Title
  
  Inflamm Bowel Dis 10・3
  
  Pages : 251-257
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto 5, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kxoczek RA, Fukushima T, Ishii H, Hibi T
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages : 829-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, et al.
- Journal Title
  
  GUT 53・9
  
  Pages : 1303-1308
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004
- Author(s)
  Okazawa A, Inoue N, et al.
- Journal Title
  
  Clin Exp Immunol 136・2
  
  Pages : 269-276
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Inoue N, et al.
- Journal Title
  
  Gastroenterology 126・3
  
  Pages : 829-839
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Inoue N, et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages : 829-839
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Gut 53(9)
  
  Pages : 1303-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003
- Author(s)
  Ezaki T, Watanabe M, Inoue N, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
- Journal Title
  
  Cancer Res 63(13)
  
  Pages : 3747-3749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulfate colitis in mice.2003
- Author(s)
  Takagi T, Kanai T, Okazawa A, Sato T, Takaishi H, Inoue N, Ogata H, Hoshino K, Takeda K, Akira S, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Scand J Gastroenterol 38(8)
  
  Pages : 837-844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003
- Author(s)
  Ezaki T, Inoue N, et al.
- Journal Title
  
  Cancer Res 63
  
  Pages : 3747-3749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice.2003
- Author(s)
  Takagi H, Inoue N, et al.
- Journal Title
  
  Scand J Gastroenterol 38
  
  Pages : 837-844
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Presentation] 大腸カプセル内視鏡は潰瘍性大腸炎粘膜治癒の評価に有用か．2014
- Author(s)
  三枝慶一郎、長沼誠、細江直樹、柏木和弘、新井万里、清原裕貴、森清人、竹下梢、南木康作、武下達矢、中里圭宏、松岡克善、久松理一、井上詠、岩男泰、緒方晴彦、金井隆典
- Organizer
  第98回日本消化器内視鏡学会関東地方会
- Place of Presentation
  シェーンバッハ・サボー（東京都千代田区）
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-26460977
[Presentation] MRエンテログラフィーによる生物学的製剤2次無効例に対するクローン病治療法の選択2014
- Author(s)
  長沼誠、久松理一、松岡克善、井上詠、岩男泰、金井隆典、緒方晴彦
- Organizer
  第69回日本大腸肛門病学会
- Place of Presentation
  横浜ベイホテル東急・パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26460977
[Presentation] Intestinal CXCR4+IgG+immature plasma cells contribute to the pathogenesis of ulcerative colitis through IgGImmune complex-Fc_YR signaling2011
- Author(s)
  Hisamatsu T, Inoue N, et al
- Organizer
  15th International Congress of Mucosal Immunology
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-07
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] Intestinal CXCR4+IgG+immature plasma cells contribute to the pathogenesis of ulcerative colitis through IgG Immune complex-FcγR signaling2011
- Author(s)
  Hisamatsu T, Uo M, Miyoshi J, Yoneno K, Inoue N, Ogata H, Kanai T, Hibi T
- Organizer
  15^<th> International Congress of Mucosal Immunology
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] 腸管マクロファージからみたクローン病のサイトカインネットワーク異常2010
- Author(s)
  久松理一、井上詠, 他
- Organizer
  第47回日本消化器免疫学会総会
- Place of Presentation
  大津
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] 腸管マクロファージからみたクローン病のサイトカインネットワーク異常2010
- Author(s)
  久松理一、鎌田信彦、高山哲朗、齋藤理子、米野和明、松岡克善、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
- Organizer
  第47回日本消化器免疫学会総会、シンポジウム
- Place of Presentation
  滋賀
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] 腸管マクロファージからみたクローン病のサイトカインネットワーク異常2010
- Author(s)
  久松理一、井上詠, 他
- Organizer
  第47回日本消化器免疫学会総会
- Place of Presentation
  大津
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] 腸管マクロファージからみたクローン病のサイトカインネットワーク異常2010
- Author(s)
  久松理一、鎌田信彦、高山哲朗、齋藤理子、米野和明、松岡克善、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
- Organizer
  第47回日本消化器免疫学会総会、シンポジウム
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] 大腸腫瘍性病変に対するESDの工夫2010
- Author(s)
  今枝博之、細江直樹、中溝裕雅、別所理恵子、齋藤理子、小池祐司、井上詠、石井良幸、長谷川博俊、岩男泰、緒方晴彦、北川雄光、日比紀文
- Organizer
  第79回日本消化器内視鏡学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-20590748
[Presentation] クローン病におけるCD14+腸管マクロファージの抗原提示能について2009
- Author(s)
  久松理一, 井上詠, 他
- Organizer
  第46回日本消化器免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] IL-10KOマウスにおけるマクロファージからのIL-12過剰産生機序の解明2009
- Author(s)
  成瀬浩史、久松理一、鎌田信彦、岡本晋、井上詠、金井隆典、日比紀文
- Organizer
  第46回日本消化器免疫学会
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] IL-10KOマウスにおけるマクロファージからのIL-12過剰産生機序の解明2009
- Author(s)
  成瀬浩史、久松理一、鎌田信彦、岡本晋、井上詠、金井隆典、日比紀文
- Organizer
  第46回日本消化器免疫学会、一般演題
- Place of Presentation
  愛媛
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] 胆汁酸はTGR5受容体を介してIL-12低産生型樹状細胞に分化誘導する/Bile acids generate IL-12 hypoproducingDCs via Tgr5 signaling pathway2009
- Author(s)
  Saito R, Hisamatsu T, Takayama T, Kamada N, Ando S, Inoue N, Okamoto S, Kanai T, Hibi T
- Organizer
  第39回日本免疫学会総会・学術集会、ワークショップ
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病におけるCD14+腸管マクロファージの抗原提示能について2009
- Author(s)
  久松理一、井上詠, 他
- Organizer
  第46回日本消化器免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病におけるCD14+腸管マクロファージの抗原提示能について2009
- Author(s)
  久松理一、鎌田信彦、本田治樹、北爪美奈、井上詠、岡本晋、金井隆典、日比紀文
- Organizer
  第46回日本消化器免疫学会、シンポジウム
- Place of Presentation
  愛媛
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病におけるCD14+腸管マクロファージの抗原提示能について2009
- Author(s)
  久松理一、鎌田信彦、本田治樹、北爪美奈、井上詠、岡本晋、金井隆典、日比紀文
- Organizer
  第46回日本消化器免疫学会、シンポジウム
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] 胆汁酸はTGR5受容体を介してIL-12低産生型樹状細胞に分化誘導する/Bile acids generate IL-12 hypoproducing DCs via Tgr5 signaling pathway2009
- Author(s)
  Saito R, Hisamatsu T, Takayama T, Kamada N, Ando S, Inoue N, Okamoto S, Kanai T, Hibi T
- Organizer
  第39回日本免疫学会総会・学術集会、ワークショップ
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590820
[Presentation] 早期大腸癌の内視鏡摘除後における大腸内視鏡サーベイランスの検討2009
- Author(s)
  井田陽介、今枝博之、細江直樹、中溝裕雅、別所理恵子、斉藤理子、小池祐司、井上詠、長谷川博俊、岩男泰、緒方晴彦、杉野吉則、北川雄光、日比紀文
- Organizer
  第27回日本大腸検査学会総会
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-20590748
[Presentation] MCP-1依存性腸管マクロファージサブセットの腸管免疫恒常性における役割2008
- Author(s)
  高田康裕、久松理一、鎌田信彦、斎藤理子、高山哲朗、市川仁志、小林拓、知念寛、井上詠、岡本晋、日比紀文
- Organizer
  第45回日本消化器免疫学会、一般演題
- Place of Presentation
  京都
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病における腸管マクロファージの腸内細菌認識異常 -IL-23を中心とした慢性炎症サイクル-2008
- Author(s)
  久松理一、鎌田信彦、小林拓、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
- Organizer
  第45回日本消化器免疫学会、シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病における腸管マクロファージの腸内細菌認識異常-IL-23を中心とした慢性炎症サイクルー2008
- Author(s)
  久松理一、井上詠、他
- Organizer
  第45回日本消化器免疫学会
- Place of Presentation
  京都
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] Mucosal CD4+ T cells with high CD26 surface expression are enriched for memory Thl cells and involved in the pathogenesis of inflammatory bowel disease2007
- Author(s)
  Inoue N, Hibi T, et. al.
- Organizer
  15th United Gastroenterology Week
- Place of Presentation
  Paris,France
- Year and Date
  2007-10-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Presentation] Mucosal CD4+T cells with high CD26 surface expression are enrichedfor memory Th1 cells and involved in the pathogenesis of inflammatorybowel disease2007
- Author(s)
  Inoue N, Hibi T, et. al.
- Organizer
  15th United Gastroenterology Week
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-29
- Data Source
  KAKENHI-PROJECT-17590677
[Presentation] Mucosal CD^<4+>T cells with high CD26 surface expression are enriched for memory Th1 cells and involved in the pathogenesis of inflammatory bowel disease2007
- Author(s)
  Inoue, N, Hibi, T, et. al.
- Organizer
  15th United Gastroenterology Week
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Presentation] A new, rapid, effective, tolerable, and safe preparation suitable for colonoscopy: a morning-only preparation using reduced-volume polyethylene glycol and electrolyte solution (peg-els) plus ascorbic acid
- Author(s)
  Inoue　N, Iwao Y, Matsuzaki J, Yoshida T, Shimizu R, Takayama M, Sugino Y
- Organizer
  Asian Pacific Digestive Week 2014
- Place of Presentation
  バリ（インドネシア）
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-26460977

1. HIBI Toshifumi (50129623)

# of Collaborated Projects : 5results

# of Collaborated Products : 40results
2. IWAO Yasushi (40168547)

# of Collaborated Projects : 2results

# of Collaborated Products : 9results
3. ISHIKAWA Hiromichi (20051667)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
4. OKAMOTO Susumu (70255446)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
5. HISAMATSU Tadakazu (60255437)

# of Collaborated Projects : 1results

# of Collaborated Products : 14results
6. WATANABE Mamoru (10175127)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
7. MORIMOTO Chikao (30119028)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. YAJIMA Tomoharu (70306710)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. NOMURA Tatsuji (10072399)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 光山慶一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
11. 金井隆典

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

INOUE Nagamu 井上 詠

Research Projects

Research Products

Co-Researchers

重症潰瘍性大腸炎に対する治療戦略-組織標的プロテオミクス解析による治療効果予測Principal InvestigatorOngoing

Principal Investigator

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Importance of dysregulated autophagy to intracellular parasiting bacteria in the pathogenesis of Crohn's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Elucidation of intestinal mucosal immune system through the intracellular processing mechanisms of bacteria and its application for novel therapy of inflammatory bowel diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Establishment of cancer surveillance using serum anti-p53 antibody in patients with ulcerative colitis

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

潰瘍性大腸炎合併大腸癌に対する新しいサーベイランス法の確立-抗p53抗体の有用性

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of intestinal flora in the pathogenesis of chronic'colitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel mouse model of human Crohn's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

免疫グロブリン可変領域遺伝子よりみた潰瘍性大腸炎病変粘膜内自己抗体産生細胞の特性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クローン病類似大腸炎モデルの作製と_<rs>CD4による新たな治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クローン病の大腸炎症局所湿潤T細胞の抗原受容体β鎖可変領域遺伝子再構成の検討Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Adalimumab for the treatment of Japanese patients with intestinal Behçet's disease.2015

Author(s)

Journal Title

Data Source

[Journal Article] Risk factors for decreased bone mineral density in inflammatory bowel disease: A cross-sectional study.2015

Author(s)

Journal Title

Data Source

[Journal Article] Risk and Management of Intra-Abdominal Abscess in Crohn's Disease Treated with Infliximab2014

Author(s)

Journal Title

Data Source

[Journal Article] Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease2012

Author(s)

Journal Title

Data Source

[Journal Article] Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease2012

INOUE Nagamu 井上詠

[Journal Article] 消化器疾患と樹状細胞病態の解明と治療法の開発クローン病におけるCD14+腸管マクロファージの抗原提示能について2010

[Journal Article] 消化器疾患と樹状細胞病態の解明と治療法の開発クローン病におけるCD14+腸管マクロファージの抗原提示能について2010