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TSUZAKA Kensei  津阪 憲政

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… Alternative Names

津坂憲 政  ツザカケン セイ

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Researcher Number 00245490
Other IDs
Affiliation (based on the past Project Information) *help 2009 – 2013: Tokyo Dental College, 歯学部, 准教授
2000 – 2007: Saitama Medical School, Instructor, 医学部, 講師
1997 – 2000: 埼玉医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
膠原病・アレルギー・感染症内科学 / 内科学一般
Except Principal Investigator
内科学一般 / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
alternative splicing / 全身性エリテマトーデス / signal transduction / mRNA 3'UTR / TCRζ鎖 / EXTL2 / syndecan / Systemic lupus erythematosus / mRNA3'UTR / MA5.8 … More / シンデカン / TCR ζ / exon deletion / syndecan-1 / cDNA microarray / ヘパラン硫酸 / signla transduction / Syndecan / TCRζ / 半定量PCR法 / dimerization / In vitro translation / RNA結合タンパク / 3' UTR / ノックアウトマウス / TCR / 3'UTR / knockout mouse / SLE / TCR zeta / クローニング / 自己抗体 / クローリング / 分子生物学 / 自己免疫疾患 / 抗核抗体 / 抗DNA抗体 / リボゾーム蛋白S1 … More
Except Principal Investigator
autoimmunity / SLE / CD103 / TCRζ chain / BAFF / 自己免疫 / インテグリン / apoptosis / adhesion / epithelial cells / Integrins / integrin / adherin / epithelial injuries / カドヘリン / 上皮障害 / microarray / splicing variants / autoantibody / 3'untranslated region / splicing / 3' untranslated region / T lymphocytes / tyrosine phosphorylation / CD3 zeta chain / lupus / T cell receptor / signaal transduction / チロシンリン酸化 / T細胞リセプター / シグナル伝達 / TCRζ鎖 / E-cadherin / シェ-グレン症候群 / シェーグレン症候群 / アポトーシス / 組織障害 / E-カドヘリン / E-cadherins / PTPN1 / JMJD1A / 機能解析 / 末梢血 / FAM20A / 14-3-3zeta / 発現異常 / mRNA / 病態形成 / 網羅的遺伝子解析 / 遺伝子発現 / DNAマイクロアレイ / 関節リウマチ Less
  • Research Projects

    (9 results)
  • Research Products

    (88 results)
  • Co-Researchers

    (6 People)
  •  Identification and characterization of pathogenesis related molecules in early rheumatoid arthritis by DNA microarray

    • Principal Investigator
      TAKEUCHI Tsutomu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Keio University
  •  Mechanism of systemic lupus erythematosus accompanied with the aberrant TCR zeta mRNA 3'UTRPrincipal Investigator

    • Principal Investigator
      TSUZAKA Kensei
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Dental College
  •  Molecular mechanism and its regulation of heterophilic adhesion between α E 3 7 (CD103) and E-cadherin in autoimmune epithelial injury

    • Principal Investigator
      TAKEUCHI Tsutomu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Saitama Medical University
  •  Decreased expression of TCRζ and signal transduction due to the aberrantexpression of the TCR mRNA in SLE patient T cellsPrincipal Investigator

    • Principal Investigator
      TSUZAKA Kensei
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Saitama Medical University
  •  Molecular mechanism and possible therapeutic target of BAFF upregulation in SLE

    • Principal Investigator
      TAKEUCHI Tsutomu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical School
  •  Analysis of the aberrant TCRζ mRNA 3'UTR in SLE patient T cellsPrincipal Investigator

    • Principal Investigator
      TSUZAKA Kensei
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical School
  •  全身性エリテマトーデス患者T細胞に発現されるTCRζ鎖の異常に関する研究

    • Principal Investigator
      TAKEUCHI Tsutomu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical School
  •  リボゾーム蛋白S1による抗DNA抗体産生の機序に関する研究Principal Investigator

    • Principal Investigator
      津坂 憲政 (津坂憲 政)
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical University
  •  Role of alphaEbeta7 on tissue destruction of autoimmune diseases

    • Principal Investigator
      TAKEUCHI Tsutomu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical School

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] SLEではT細胞にシグナル異常があるか。皮膚科膠原病診療のすべて。古江増隆・佐藤伸一編集2011

    • Author(s)
      津坂憲政
    • Publisher
      中山書店(東京)
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Book] リウマチ、膠原病最新トピックス2005

    • Author(s)
      津坂 憲政
    • Publisher
      診断と治療社(東京)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] シェーグレン症候群2013

    • Author(s)
      津坂憲政, 浮地賢一郎
    • Journal Title

      ザ・クインテッセンス

      Volume: 32 Pages: 142-146

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] RAにおけるADAMTS-10の異常発現と血管新生2013

    • Author(s)
      津坂憲政
    • Journal Title

      リウマチ科

      Volume: 50 Pages: 112-114

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] CD3ζdefects in systemic lupus erythematosus2012

    • Author(s)
      Takeuchi T, Suzuki K, Kondo T, Yoshimoto K, Tsuzaka K
    • Journal Title

      Ann Rheum Dis

      Volume: 71(Suppl), 2

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome2011

    • Author(s)
      Yoshimoto K, Tanaka M, Kojima M, Setoyama Y, Kameda H, Suzuki K, Tsuzaka K, Ogawa Y, Tsubota K, Abe T, Takeuchi T
    • Journal Title

      Arthritis Res Ther

      Volume: 13(5)(Epub)

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] Decreased mRNA expression of two FOXP3 isoforms in peripheral blood mononuclear cells from patients with rheumatoid arthritis and systemic lupus erythematosus2011

    • Author(s)
      Suzuki K, Setoyama Y, Yoshimoto K, Tsuzaka K, Abe T, Takeuchi T
    • Journal Title

      Int J Immunopathol Pharmacol

      Volume: 24 Pages: 7-14

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] Decreased mRNA expression of two Foxp3 isoforms in peripheral blood mononuclear cells from patients with rheumatoid arthritis and systemic lupus erythematosus2011

    • Author(s)
      Suzuki K, Setoyama Y, Yoshimoto K, Tsuzaka K, Abe T, Takeuchi T
    • Journal Title

      Int J Immunopathol and Pharmacology

      Volume: 24 Pages: 7-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390259
  • [Journal Article] Single center prospective study of tacrolimus efficacy and safety in treatment of rheumatoid arthritis2011

    • Author(s)
      Suzuki K, Kameda H, Amano K, Nagasawa H, Takei H, Sekiguchi N, Nishi E, Ogawa H, Tsuzaka K, Takeuchi T
    • Journal Title

      Rheumatol Int

      Volume: 31 Pages: 757-763

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] Reduced Expression of TCR zeta Is Involved in the Abnormal Production of Cytokines by Peripheral T Cells of Patients with Systemic Lupus Erythematosus2010

    • Author(s)
      Yoshimoto K, Setoyama Y, Tsuzaka K, Abe T, Takeuchi T
    • Journal Title

      J Biomed Biotechnol

      Volume: (Epub)

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] ADAMTS5 is a biomarker for prediction of the response to Infliximab in patients with rheumatoid arthritis2010

    • Author(s)
      Tsuzaka K, Itami Y, Takeuchi T, Shinozaki N, Morishita T
    • Journal Title

      J Rheumatol

      Volume: 37 Pages: 1454-1460

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] ADAMTS5 is a biomarker for prediction of the response to Infliximab in patients with rheumatoid arthritis.2010

    • Author(s)
      Tsuzaka K, Itami Y, Takeuchi T, et al.
    • Journal Title

      J Rheumatol

      Volume: 37 Pages: 1454-1460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] Reduced Expression of TCR zeta Is Involved in the Abnormal Production of Cytokines by Peripheral T Cells of Patients with Systemic Lupus Erythematosus2010

    • Author(s)
      Yoshimoto K, Setoyama Y, Tsuzaka K, et al.
    • Journal Title

      J Biomed Biotechnol

      Volume: (Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] IgG4関連自己免疫性疾患(形質細胞浸潤)2009

    • Author(s)
      津坂憲政
    • Journal Title

      別刷日本臨床呼吸器症候群

      Pages: 135-137

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] 関節リウマチ2009

    • Author(s)
      津坂憲政
    • Journal Title

      小児科 50

      Pages: 1999-2004

    • Data Source
      KAKENHI-PROJECT-21591268
  • [Journal Article] The conservative sequences in 3'UTR of TCRζ mRNA regulate the production of TCRζ and TCR/CD3 complex in SLE T cells2008

    • Author(s)
      Tsuzaka Kensei, et. al.
    • Journal Title

      BBRC 367

      Pages: 311-317

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] T The conservative sequences in 3' UTR of TCRtξ mRNA regulate the production of TCRξ and TCR/CD3 complex in SLE T cells.2008

    • Author(s)
      Tsuzaka, K, Itami, Y, Kumazawa, C, Suzuki, M, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
    • Journal Title

      BBRC 367

      Pages: 311-317

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] The conservative sequences in 3'UTR of TCRζ mRNA regulate the production of TCRζ and TCR/CD3 complex in SLE T cells.2008

    • Author(s)
      Tsuzaka Kensei, et. al.
    • Journal Title

      BBRC 367

      Pages: 311-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] Down-regulation of Fas-ligand mRNA Shogren' syndrome patients with enlarged exocrine glands2007

    • Author(s)
      Tsuzaka Kensei, et. al.
    • Journal Title

      Autoimmunity 40

      Pages: 497-502

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] Down-regulation of Fas-ligand mRNA in Sjogren's syndrome patients with enlarged exocrine glands2007

    • Author(s)
      Tsuzaka, K, Matsumoto, Y, Sasaki, Y, et. al.
    • Journal Title

      Autoimmunity 40

      Pages: 497-502

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Prospective study of low dose cyclosporine A in patients with refractory lupus nephritis2007

    • Author(s)
      Ogawa, H, Kameda, H, Nagasawa, H, Sekiguchi, N, Takei, H, Tsuzaka, K, Amano, K, d Takeuchi, T
    • Journal Title

      Mod Rheum 17

      Pages: 92-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] Down-regulation of Fas-ligand mRNA Shogren' syndrome patients with enlarged exocrine glands2007

    • Author(s)
      Tsuzaka, K, Matsumoto, Y, Sasaki, Y, Abe, T, Tsubota, K, Takeuchi, T
    • Journal Title

      Autoimmunity 40

      Pages: 497-502

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] Down-regulation of Fas-ligand mRNA in Sjogren's syndrome patients with enlarged exocrine glands2007

    • Author(s)
      Tsuzaka K, Matsumoto Y, Sasaki Y, et. al.
    • Journal Title

      Autoimmunity 40

      Pages: 497-502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Down-regulation of Fas-ligand mRNA Shogren' syndrome patients with enlarged exocrine glands2007

    • Author(s)
      Tsuzaka Kensei, et. al.
    • Journal Title

      Autommunity 40

      Pages: 497-502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] Efficacy and Safety of Tacrolimus in Patients with rheumatoid arthritis in clinical practice : Significant role of blood concentration measurement for preventing severe adverse events2007

    • Author(s)
      Suzuki, K, Takei, H, Kameda, H, Nagasawa, H, Sekiguchi, N, Nishi, E, Ogawa, H, Tsuzaka, K, Amano, K, Takeuchi, T
    • Journal Title

      Arthritis Rheum S 35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] DNA microarray gene expression profile of T cells with splice variants of TCRz mRNA observed in SLE2006

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, Shiraishi, K, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
    • Journal Title

      J Immunol 176

      Pages: 949-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] TCRz mRNA splice variant forms observed in peripheral blood T cells from systemic lupus erythematosus patients2006

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, Shiraishi, K, Setoyama, Y, Yoshimoto, K, Abe, T, Takeuchi, T
    • Journal Title

      Springer Seminars in Immunopathology 28

      Pages: 185-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] DNA microarray gene expression profile of T cells with the splice variants of TCRζ mRNA observed in SLE2006

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, et. al.
    • Journal Title

      J Immunol 176

      Pages: 949-956

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] DNA microarray gene expression profile of T cells with the splice variants of TCRζ mRNA observed in SLE2006

    • Author(s)
      Tsuzaka K, Nozaki K, Kumazawa C, et. al.
    • Journal Title

      J Immunol 176

      Pages: 949-956

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] TCRゼータ鎖ヴァリアントに起因する二次的分子異常の検索2006

    • Author(s)
      津坂憲政
    • Journal Title

      リウマチ科 35

      Pages: 6-10

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Molecular abnormalities of T cells in systemic lupus erythematosus2006

    • Author(s)
      Takeuchi, T, Tsuzaka, T, Kameda, H, Amano, K
    • Journal Title

      APLAR journal of Rheum 9

      Pages: 365-71

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] TCRζ mRNA splice variant forms observed in the peripheral blood T cells from systemic lupus erythematosus patients2006

    • Author(s)
      Tsuzaka K, Nozaki K, Kumazawa C, et. al.
    • Journal Title

      Springer Semin lmmunopathol 28

      Pages: 185-193

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] DNA microarray gene expression profile of T cells with splice variants of TCRz mRNA observed in SLE2006

    • Author(s)
      Tsuzaka Kensei
    • Journal Title

      J Immunol 176

      Pages: 949-956

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] DNA microarray gene expression profile of T cells with cplice variants of TCRζ mRNA observed in SLE.2006

    • Author(s)
      Tsuzaka Kensei
    • Journal Title

      J Immunology 176

      Pages: 949-956

    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] Aberrant expression of BAFF in T cells of systemic lupus erythematosus, which is recapitulated by a human T cell line, Loucy2006

    • Author(s)
      Yoshimoto, K, Takahashi, Y, Ogasawara, M, Setoyama, Y, Suzuki, K, Tsuzaka, K, Abe, T, Takeuchi, T
    • Journal Title

      Int Immunol 18

      Pages: 1189-96

    • NAID

      10020618413

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Journal Article] TCRζ mRNA splice variant forms observed in the peripheral blood T cells from systemic lupus erythematosus patients2006

    • Author(s)
      Tsuzaka Kensei
    • Journal Title

      Springer Semin Immunopathol 28

      Pages: 185-193

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] DNA microarray gene expression profile of T cells with the splice variants of TCRζ mRNA observed in SLE2006

    • Author(s)
      Tsuzaka Kensei
    • Journal Title

      Journal of Immunology 176

      Pages: 949-956

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] TCRζ mRNA splice variant forms observed in the peripheral blood T cells from systemic lupus erythematosus patients2006

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, et. al.
    • Journal Title

      Springer Semin Immunopathol 28

      Pages: 185-193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] A splice variant of the TCR ζ mRNA lacking exon 7 leads to the down-regulation of TCR ζ, the TCR/CD3 complex, and IL-2 production in SLE T cells2005

    • Author(s)
      Tsuzaka K, Setoyama Y, Yoshimoto K, et.
    • Journal Title

      J Immunol 174

      Pages: 3518-3525

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] T cell abnormalities in systemic lupus erythematosus2005

    • Author(s)
      Takeuchi, T, Tsuzaka, K, Abe, T, et. al.
    • Journal Title

      Autoimmunity 38

      Pages: 339-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Critical role of the fifth domain of E-cadherin for heterophilic adhesion with αEβ7, but not for homophilic adhesion.2005

    • Author(s)
      Shiraishi K, Tsuzaka K, Kumazawa C, et al.
    • Journal Title

      J Immunol 175

      Pages: 1014-1021

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] TCRζ鎖障害によって惹起される二次的分子異常2005

    • Author(s)
      津坂憲政
    • Journal Title

      炎症と免疫 13

      Pages: 633-639

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] A splice variant of the TCRζmRNA lacking exon 7 leads to the down-regulation of TCR ζ the TCR/CD3 complex, and IL-2 production in systemic lupus erythematosus T cells.2005

    • Author(s)
      Tsuzaka K, Setoyama Y, Yoshimoto K, Shiraishi K, et al.
    • Journal Title

      Journal of Immunology 174

      Pages: 3518-3525

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Therapeutic targets in misguided T cells in systemic lupus erythematosus.2005

    • Author(s)
      Takeuchi T, Tsuzaka K, Kameda H, et al.
    • Journal Title

      Current Drug Target 4

      Pages: 295-298

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Therapeutic targets in misguided T cells in systemic lupus erythematosus2005

    • Author(s)
      Takeuchi, T, Tsuzaka, K, Kameda, H, et. al.
    • Journal Title

      Current Drug Target 4

      Pages: 295-298

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Critical role of the fifth domain of E-cadherin for heterophilic adhesion with a E β 7, but not for homophilic adhesion2005

    • Author(s)
      Shiraishi, K, Tsuzaka, K, Kumazawa, C, et. al.
    • Journal Title

      J Immunol 175

      Pages: 1014-1021

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] A splice variant of the TCR mRNA lacking exon 7 leads to the down-regulation of TCRζ, the TCR/CD3 complex, and IL-2 production in SLE T cells.2005

    • Author(s)
      Tsuzaka, K, Setoyama, Y, Yoshimoto, K, et. al.
    • Journal Title

      J Immunol 174

      Pages: 3518-3525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] T cell abnormalities in systemic lupus erythematosus.2005

    • Author(s)
      Takeuchi T, Tsuzaka K, Abe T, et al.
    • Journal Title

      Autoimmunity 38

      Pages: 339-346

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] Altered expression of the T cell receptor-CD3 complex in systemic lupus erythematosus.2004

    • Author(s)
      Takeuchi T, Tsuzaka K, Abe T
    • Journal Title

      Int Rev Immunol 23

      Pages: 273-291

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] SLE発症前の自己抗体2004

    • Author(s)
      津坂憲政, 竹内勤
    • Journal Title

      内科 93

      Pages: 972-973

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] SLE患者に認められるTCRζ鎖スプライス・ヴァリアントの役割2004

    • Author(s)
      津坂憲政
    • Journal Title

      分子リウマチ 3

      Pages: 183-191

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] SLE T細胞の早期シグナル伝達異常2004

    • Author(s)
      津坂憲政
    • Journal Title

      臨床免疫 42

      Pages: 427-434

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Journal Article] 全身性エリテマトーデス患者T細胞におけるTCRζ鎖mRNAスプライス異常2004

    • Author(s)
      津坂憲政
    • Journal Title

      最新医学 59

      Pages: 2165-2178

    • Data Source
      KAKENHI-PROJECT-16590993
  • [Presentation] Plasma short-talin is a new rheumatoid arthritis monitoring biomarker independent of the inflammatory markers.2013

    • Author(s)
      Tsuzaka K, Takao M, Nishida J
    • Organizer
      2013 ACR Annual Scientific Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] ADAMTS5 is a biomarker for the efficacy prediction of tocilizumab in rheumatoid arthritis2013

    • Author(s)
      Tsuzaka K, Takao M, Nishida J
    • Organizer
      2013 ACR Annual Scientific Meeting
    • Place of Presentation
      SanDiego
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] ADAMTS5 is a biomarker for the efficacy prediction of tocilizumab in rheumatoid arthritis.2013

    • Author(s)
      Tsuzaka K, Takao M, Nishida J
    • Organizer
      2013 ACR Annual Scientific Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Plasma short-talin is a new rheumatoid arthritis monitoring biomarker independent of the inflammatory markers2013

    • Author(s)
      Tsuzaka K, Takao M, Nishida J
    • Organizer
      2013 ACR Annual Scientific Meeting
    • Place of Presentation
      SanDiego
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] ニューモシスティス肺炎合併膠原病患者の気道検体Pneumocystis jiroveci DNA濃度、血清βD-glucan値の臨床的検討-気道検体conventional PCR陰性例を含む-2013

    • Author(s)
      阿部治男、津坂憲政
    • Organizer
      第57回日本リウマチ学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] 関節リウマチ患者に対するトシリズマブ休薬基準の検討(多施設共同研究)2013

    • Author(s)
      金子礼志、津坂憲政、海辺剛志
    • Organizer
      第57回日本リウマチ学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] 関節リウマチの新規診断マーカーおよびモニタリングマーカーとしての血中タリン2012

    • Author(s)
      津坂憲政
    • Organizer
      第56回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Talin is cleaved and expressed as a short form predominantly in patients with rheumatoid arthritis2012

    • Author(s)
      Tsuzaka K, Takao Masako, Shinozaki N, Nishida J
    • Organizer
      2012 ACR Annual Scientific Meeting
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Talin is cleaved and expressed as a short form predominantly in patients with rheumatoid arthritis.2012

    • Author(s)
      Tsuzaka K
    • Organizer
      2012 ACR Annual Scientific Meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Plasma talin is a new diagnostic and monitoring marker for rheumatoid arthritis2011

    • Author(s)
      Tsuzaka K, Itami Y, Shinozaki N, Morishita T
    • Organizer
      2011 ACR Annual Scientific Meeting
    • Place of Presentation
      米国、シカゴ
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Plasma talin is a new diagnostic and monitoring marker for rheumatoid arthritis2011

    • Author(s)
      Tsuzaka K, Itami Y, Shinozaki N, Morishita T
    • Organizer
      2011 ACR Annual Scientific Meeting
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Baseline ADAMTS5 expression could sort the prediction of response to infliximab or adalimumab in patients with rheumatoid arthritis2010

    • Author(s)
      Tsuzaka K, Itami Y, Shinozaki N, Morishita T
    • Organizer
      2010 ACR Annual Scientific Meeting
    • Place of Presentation
      Atlanta
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] Baseline ADAMTS5 expression could sort the prediction of response to infliximab or adalimumab in patients with rheumatoid arthritis2010

    • Author(s)
      Tsuzaka, K, et al.
    • Organizer
      ACR Annual Scientific Meeting
    • Place of Presentation
      米国、アトランタ
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] ADAMTS5 is a biomarker for prediction of the response to infliximab in patients with rheumatoid arthritis2009

    • Author(s)
      Tsuzaka K, et al.
    • Organizer
      ACR 72nd Annual Meeting
    • Place of Presentation
      米国、フィラデルフィア
    • Year and Date
      2009-10-19
    • Data Source
      KAKENHI-PROJECT-21591268
  • [Presentation] 14-kd protein binds to the conservative region in TCR zeta mRNA 3' UTR and regulates the production of TCR zeta and TCR/CD3 complex2007

    • Author(s)
      Tsuzaka, K, Itami, Y, Kumazawa, C, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
    • Organizer
      American College of Rheumatology 71st Annual Meeting
    • Place of Presentation
      Boston, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] A negative role of a unique integrin alphaEbeta7 on proliferative capability of human T cell line2007

    • Author(s)
      Kumazawa, C, Shiraishi, K, Tsuzaka, K, Takeuchi, T
    • Organizer
      The EULAR annual congress of rheumatology
    • Place of Presentation
      Barcelona, Spain
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Possible involvement of MMP in the production of soluble BAFF in human T cells2007

    • Author(s)
      Yoshimoto, K, Takahashi, Y, Setoyama, Y, Suzuki, K, Tsuzaka, K, Abe, T, Takeuchi, T
    • Organizer
      The EULAR annual congress of rheumatology, Barcelona
    • Place of Presentation
      Spain
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Decreased expression of the glycosylated syndecan 4 accompanied with down-regulation of TCR zeta in SLE patient T cells2007

    • Author(s)
      Tsuzaka, K, Itami, Y, Kumazawa, C, et. al.
    • Organizer
      ACR71st Annual Meeting Boston
    • Place of Presentation
      U. S. A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Presentation] Decreased expression of the glycosylated syndecan 4 accompanied with down-regulationof TCR zeta in SLE patient T cells2007

    • Author(s)
      Tsuzaka Kensei
    • Organizer
      American College of Rheumatology, 71st Annual Meeting
    • Place of Presentation
      Boston,U.S.A
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Decreased expression of theglycosylated syndecan 4 accompanied with down-regulation of TCR zeta in SLE patient T cells2007

    • Author(s)
      Tsuzaka K, Itami Y, Kumazawa C
    • Organizer
      ACR 71st Annual Meeting
    • Place of Presentation
      Boston
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Presentation] Efficacy and safety of tacrolimus in patients with rheumatic disease : Appropriate clinical application for various rheumatic conditions2007

    • Author(s)
      Suzuki, K, Kameda, H, Amano, K, Nagasawa, H, Sekiguchi, N, Takei, H, Nishi, E, Okuyama, A, Ogawa, H, Tsuzaka, K, Takeuchi, T
    • Organizer
      American College of Rheumatology 71st Annual Meeting
    • Place of Presentation
      Boston, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] 14-kd protein binds to the conservative region in TCR zeta mRNA 3'UTR and regulates the production of TCR zeta and TCR/CD3 complex.2007

    • Author(s)
      Tsuzaka Kensei
    • Organizer
      American College of Rheumatology, 71st Annual Meeting
    • Place of Presentation
      Boston,U.S.A.
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Decreased expression of the glycosylated syndecan 4 accompanied with down-regulation of TCR zeta in SLE patient T cells2007

    • Author(s)
      Tsuzaka, K, Itami, Y, Kumazawa, C, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
    • Organizer
      American College of Rheumatology 71st Annual Meeting
    • Place of Presentation
      Boston, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] TCR ξ and TCR/CD3 expression from the TCR C mRNA with deleted form of the conservative sequences in 3' UTR is down-regulated due to its instability2007

    • Author(s)
      Tsuzaka, K, Itami, Y, Kumazawa, C, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
    • Organizer
      37th Japanese society for Immunology
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] SLE患者T細胞におけるシンデカン分子糖鎖発現異常2007

    • Author(s)
      津坂 憲政
    • Organizer
      第51回日本リウマチ学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Possible involvement of MMP-9 in the production of BAFF in T cells2007

    • Author(s)
      Yoshimoto, K, Setoyama, Y, Tsuzaka, K, Ogawa, Y, Tsubota, K, Abe, T, Takeuchi, T
    • Organizer
      American uollege of Nheumatology Ylst Annual Meeting
    • Place of Presentation
      Boston, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] TCRζ and TCR/CD3 expression from the TCRζ mRNA with deleted form of the conservative se uences in 3'U丁R is down-reulated due to its instability.2007

    • Author(s)
      Tsuzaka Kensei
    • Organizer
      第37回日本免疫学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Decreased expression of the glycosylated syndecan 4 accompanied with down-regulation of TCR zeta in SLE patient T cells.2007

    • Author(s)
      Tsuzaka K, Itami Y, Kumazawa C, et. al.
    • Organizer
      American College of Rheumatology, 71st Annual Scientific Meeting
    • Place of Presentation
      アメリカ、ボストン
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Presentation] Efficacy and Safety of Tacrolimus in Patients With Rheumatoid Arthritis in Clinical Practice : Significant Role of Blood Concentration Measurement for Preventing Severe Adverse Events2006

    • Author(s)
      Suzuki, K, Takei, H, Kameda, H, Nagasawa, H, Sekiguchi, N, Nishi, E, Ogawa, H, Tsuzaka, K, Amano, K, Takeuchi, T
    • Organizer
      70th Annual Meeting, Washington
    • Place of Presentation
      D. C., U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Responsible region in 3'UTR of TCRz mRNA for producing TCR/CD3 including TCRz in SLE T cells2006

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, Setoyama, Y, Shiraishi, K, Abe, T, Takeuchi, T
    • Organizer
      16th European Congress of Immunology
    • Place of Presentation
      Paris, France
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Responsible region in 3'UTR of TCRz mRNA for producing TCR/CD3 including TCRz in SLE T cells2006

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, et. al.
    • Organizer
      16th European Congress of Immunology Paris
    • Place of Presentation
      France
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Presentation] Aberrant expression of BAFF in SLE T cells2006

    • Author(s)
      Yoshimoto, K, Takahashi, Y, Setoyama, Y, Suzuki. K, Tsuzaka. K, Abe. T, Takeuchi, T
    • Organizer
      The EULAR annual congress of rheumatology
    • Place of Presentation
      Amsterdam, Holland
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] Decreased expression of glycosylated syndecan families due to reduced production of EXTL2 in SLE patient T cells2006

    • Author(s)
      Tsuzaka Kensei
    • Organizer
      第36回日本免疫学会総会
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591122
  • [Presentation] DNA microarray gene expression profile of T cells with the splice variants of TCR mRNA observed in SLE2004

    • Author(s)
      Tsuzaka, K, Setoyama, Y, Yoshimoto, K, et. al.
    • Organizer
      ACR 68th Annual Meeting San Antonio
    • Place of Presentation
      U. S. A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • [Presentation] The conservative region in 3'UTR of TCRz mRNA regulates the production of TCRζ in SLE T cells

    • Author(s)
      Tsuzaka, K, Nozaki, K, Kumazawa, C, et. al.
    • Organizer
      ACR 69th Annual Meeting San Diego
    • Place of Presentation
      U. S. A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590993
  • 1.  TAKEUCHI Tsutomu (50179610)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 25 results
  • 2.  AMANO Koichi (00175928)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  NAGASAWA Hayato (20306343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KATSUYA Suzuki (70306695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  YOSHIMOTO Keiko (20383292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 6.  白石 清之 (10383291)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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