FUJITA Takuya 藤田卓也

… Alternative Names

Researcher Number	00247785
Other IDs
Affiliation *help	2011 – 2018 : 立命館大学, 薬学部, 教授 2008 : Ritsumeikan University, 薬学部, 教授 2007 : Ritsumeikan University, 情報理工学部, 教授 2000 – 2006 : 京都薬科大学, 薬学部, 助教授 1998 – 1999 : 京都薬科大学, 薬学部, 講師 1995 – 1997 : 京都薬科大学, 薬学部, 助手 1993 : 京都薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Medical pharmacy / 応用薬理学・医療系薬学 / Biological Sciences Except Principal Investigator 応用薬理学・医療系薬学 / Physical pharmacy / Physical pharmacy / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator アミノ酸トランスポーター / RT-PCR / アストロサイト / PEPT2 / gabapentin / ペプチドトランスポーター / TCA回路中間体 / 中枢神経系 / Gabapentin / Caco-2 … More Except Principal Investigator 吸収促進剤 / 生理活性ペプチド / 経肺吸収 / タンパク分解酵素阻害剤 / インスリン / 膜抵抗 / 消化管吸収 / 薬物排出 / 細胞送達システム / 磁場応答性リポソーム / Oral administration / P-glycoprotein / 肺吸収 / M2型マクロファージ / マイクロマシン / Drug efflux / Gastrointestinal absorption / 培養細胞 / ターゲッティング / 薬剤吸収評価 / マクロファージ / 磁場 / Absorption enhancer / Transporter / トランスポーター / 転移抑制 / リンパ移行 / 薬効評価 / ナノバイオシステム / 炎症性腸疾患 / 経口投与 / Absorption enhancement / P糖タンパク質 / アフリカツメガエル / 製剤添加物 / 肺癌 / 吸収改善 / リポソーム / 肺組織 / 高分子化修飾 / P糖タンパク / 剤形修飾 / 抗癌剤 / Pharmaceutical excipient Less

Physiological role of Na-dependent dicarboxylate transporters in central nervous systemPrincipal InvestigatorOngoing
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
An openable tubular artificial gastrointestinal micromachine for medicine effect evaluation
- Principal Investigator
  
  konishi satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Ritsumeikan University
Development of magnetically guided M2 macrophages-based cell therapy for inflammatory bowel disease
- Principal Investigator
  
  Kono Yusuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Ritsumeikan University
Biochemical properties of various organic ion transporters in central nervous systemPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Biopharmaceutical Study on Organic Solute Transporters Which Modulate Central Nervous SystemPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Biopharmaceutical Study on Organic Ions Transporters Which Act as Central Nervous System ModulatorsPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
  Kyoto Pharmaceutical University
脳の形成・発達に伴うタウリントランスポーターの発現変動と生理学的重要性Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
アストロサイトにおける代謝型GABA_B受容体の発現とGABA輸送体との機能的連関Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
Functional Linkage of Neutral amino acid transport system L and voltage-gated Ca^<2+> channels in central nervous systems.Principal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Localization and functional regulation of H^+/oligopptide transporter(s) in brainPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO PHARMACEUTICAL UNIVERSITY
塩酸イリノテカン投与による消化管上皮細胞での薬物輸送担体の発現制御機構の解明Principal Investigator
- Principal Investigator
  
  岡卓也
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
Functional modulation of drug efflux system by drug interaction and development of oral drug delivery system
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
小腸上皮細胞における薬物の代謝およびそれに付随する消化管分泌機構Principal Investigator
- Principal Investigator
  
  岡卓也
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Pharmaceutical University
脳におけるH^+-オリゴペプチドトランスポーターの局在と電気生理学的特性Principal Investigator
- Principal Investigator
  
  岡卓也
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
小腸上皮細胞に存在する有機アニオン排出機構の実証と分子クローニングPrincipal Investigator
- Principal Investigator
  
  岡卓也
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
肺培養上皮細胞系を用いた生理活性ペプチドの透過性の評価
- Principal Investigator
  
  山本昌
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
薬物の代謝・排泄器官として機能する消化管の生化学的解明Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
アフリカツメガエルの単離肺組織を用いた生理活性ペプチドの肺吸収性の評価
- Principal Investigator
  
  山本昌
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
脂肪酸および胆汁酸塩による薬物の上皮細胞透過性亢進機構の生化学的解明Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
肺癌の転移抑制を目的とした抗癌剤の高分子化修飾ならびに剤形修飾に関する研究
- Principal Investigator
  
  村西晶三
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Pharmaceutical University

All 2017 2016 2015 2013 2012 2011 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] Identity of thehigh-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter2006
- Author(s)
  V. Ganapathy and T. Fujita
- Publisher
  Adv ExpMed Biol
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Pharmacokinetic Modeling and Monte Carlo Simulation to Predict Interindividual Variability in Human Exposure to Oseltamivir and Its Active Metabolite, Ro 64-08022017
- Author(s)
  Ito M, Kusuhara K, Ose A, Kondo T, Tanabe K, Nakayama H, Horita S, Fujita T, Sugiyama Y.
- Journal Title
  
  Ito M, Kusuhara H, Ose A, Kondo T, Tanabe K, Nakayama H, Horita S, Fujita T, Sugiyama Y.
  
  Volume : 19 Pages : 286-297
- DOI
  10.1208/s12248-016-9992-0
- Peer Reviewed / Int'l Joint Research / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-26293032, KAKENHI-PROJECT-26460210
[Journal Article] Dextran sodium sulfate alters cytokine production in macrophages in vitro2016
- Author(s)
  Y Kono, S Miyoshi, T Fujita
- Journal Title
  
  Pharmazie
  
  Volume : 71 Pages : 619-624
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18851
[Journal Article] Effect of Mechanical Agitation on Cationic Liposome Transport across an Unstirred Water Layer in Caco-2 Cells.2016
- Author(s)
  Kono Y, Iwasaki A, Matsuoka K, Fujita T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume : 39 Pages : 1293-1299
- DOI
  10.1248/bpb.b16-00050
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460210
[Journal Article] An openable artificial intestinal tract system for the in vitro evaluation of medicines2015
- Author(s)
  Satoshi Konishi, Takuya Fujita, Koji Hattori, Yusuke Kono and Yoshifumi Matsushita
- Journal Title
  
  Microsystems and Nanoengineering
  
  Volume : 1 Pages : 15015-15015
- DOI
  10.1038/micronano.2015.15
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460210, KAKENHI-PROJECT-15K12526, KAKENHI-PROJECT-15K18851
[Journal Article] Studies on the Intestinal Absorption Characteristics of Sulfasalazine, a Breast Cancer Resistance Protein (BCRP) Substrate.2013
- Author(s)
  Atsuko Tomaru, Nozomi Morimoto, Mariko Morishita, Kozo Takayama, Takuya Fujita, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume : 28 Pages : 71-74
- DOI
  10.2133/dmpk.DMPK-12-NT-024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Studies on the Intestinal Absorption Characteristics of Sulfasalazine, a Breast Cancer Resistance Protein (BCRP) Substrate2013
- Author(s)
  Atsuko Tomaru, Nozomi Morimoto, Mariko Morishita, Kozo Takayama, Takuya Fujita, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume : 28 (1) Pages : 71-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Extra-renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2.2012
- Author(s)
  Atsushi Hosomi, Takeo Nakanishi, Takuya Fujita, and Ikumi Tamai
- Journal Title
  
  PLoS ONE
  
  Volume : 7 Issue : 2 Pages : e30456
- Publisher
  Public Library of Science
- DOI
  10.1371/journal.pone.0030456
- Year and Date
  2012-01-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Extra-renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG22012
- Author(s)
  Atsushi Hosomi, Takeo Nakanishi, Takuya Fujita, and Ikumi Tamai
- Journal Title
  
  PLoS ONE
  
  Volume : 7 (2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Pharmacokinetic interaction study of sulfasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP2012
- Author(s)
  Hiroyuki Kusuhara, Hidetoshi Furuie, Akihiro Inano, Akihiro Sunagawa, Sakiko Yamada, Chungyong Wu, Shinya Fukizawa, Ichiro Ieiri, Mariko Morishita, Kiminobu Sumida, Hiroshi Mayahara, Takuya Fujita, Kazuya Maeda, and Yuichi Sugiyama
- Journal Title
  
  Br. J. Pharmacol
  
  Volume : 166 (6) Pages : 1793-1803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Pharmacokinetic interaction study of sulfasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.2012
- Author(s)
  Kusuhara H, et al
- Journal Title
  
  British Journal of Pharmacology
  
  Volume : (In press) Pages : 1793-1803
- DOI
  10.1111/j.1476-5381.2012.01887.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23136101, KAKENHI-PROJECT-23590206, KAKENHI-PROJECT-24229002
[Journal Article] Quantitative evaluation of the impact of active efflux by P-gp and Bcrp at the BBB on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as surrogate.2011
- Author(s)
  Hiroshi Kodaira, Hiroyuki Kusuhara, Takuya Fujita, Junko Ushiki, Eiichi Fuse, and Yuichi Sugiyama
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume : 339 Pages : 935-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Intranasal immunization with poly(ɤ-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity2011
- Author(s)
  Keisuke Matsuo, Hayato Koizumi, Yumiko Ishii, Kazuhiko Matsuo, Takuya Fujita, Akira Yamamoto, Mitsuru Akashi, Shinsaku Nakagawa, and Naoki Okada
- Journal Title
  
  J Control. Rel
  
  Volume : 152 (2) Pages : 310-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Quantitative evaluation of the impact of active efflux by P-gp and Bcrp at the BBB on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as surrogate2011
- Author(s)
  Hiroshi Kodaira, Hiroyuki Kusuhara, Takuya Fujita, Junko Ushiki, Eiichi Fuse, and Yuichi Sugiyama
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume : 339 (3) Pages : 935-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Functional characterization and cloning of amino acid transporter B^<0,+> (ATB^<0,+>) in primary cultured rat pneumocytes2008
- Author(s)
  T. Uchiyama, T. Fujita, H. J. Gukasyan, K. -J. Kim, Z. Borok, E. D. Crandall and V. H. L. Lee
- Journal Title
  
  J. Cell. Physiol 214
  
  Pages : 645-654
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein2008
- Author(s)
  K. Morimoto, M. Nakakariya, Y. Shirasaka, C. Kakinuma, T. Fujita I. Tamai and T. Ogihara
- Journal Title
  
  Drug Metab. Dispos 36
  
  Pages : 6-9
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] P-glycoprotein restricts the penetration of Oseltamivir across the blood-brain barrier2008
- Author(s)
  A. Ose, H. Kusuhara, K. Yamatsugu, M. Kanai, M. Shibasaki, T. Fujita, A. Yamamoto and Y. Sugiyama
- Journal Title
  
  Drug Metab. Dispos 36
  
  Pages : 427-434
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Development of oligoarginine-drug conjugates linked to new peptidic self-cleavable spacers towards effective intestinal absorption2007
- Author(s)
  Y. Hayashi, K. Takayama, Y. Suehisa, T. Fujita, J.-T. Nguyen, S. Futaki, A. Yamamoto and Y. Kiso
- Journal Title
  
  Bioorg. Med. Chem Lett 17
  
  Pages : 5129-5132
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional and molecular identification of sodium-coupled dicarboxylate transporters in primary cultured cerebrocortical astrocytes and neurons2006
- Author(s)
  E. Yodoya, M. Wada, A. Shimada, H. E. Yodoya, M. Wada, A. Shimada, H. Katsukawa, N. Okada, A. Yamamoto, V. Ganapathy and T. Fujita
- Journal Title
  
  J. Neurochem 97
  
  Pages : 162-173
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Na^+-coupled citrate transporter NaC2/NaCT expressed in primary cultures of neurons from mouse cerebral cortex2006
- Author(s)
  M. Wada, A. Shimada and T. Fujita
- Journal Title
  
  Brain Res 1081
  
  Pages : 92-100
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter2006
- Author(s)
  V. Ganapathy and T. Fujita
- Journal Title
  
  Adv ExpMed Biol 576
  
  Pages : 67-76
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional expression of taurine transporter and its up-regulation in developing neurons from mouse cerebral cortex2006
- Author(s)
  T. Fujita, A. Shimada, M. Wada, S. Miyakawa and A. Yamamoto
- Journal Title
  
  Pharm. Res 23
  
  Pages : 689-696
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine2006
- Author(s)
  T. Ogihara, M. Kamiya, M. Ozawa, T. Fujita, A. Yamamoto, S. Yamashita, S. Ohnishi and Y. Isomura
- Journal Title
  
  Drug Metab. Pharmacokinet 21
  
  Pages : 238-244
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Na^+-independent choline transport in primary cultures of neurons from mouse cerebral cortex.2006
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Neuroscience Letters 393
  
  Pages : 216-221
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter.2006
- Author(s)
  Vadivel Ganapathy, Takuya Fujita
- Journal Title
  
  Advanced Experimental Medicine and Biology 576
  
  Pages : 67-76
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Na^<+>-independent choline transport in primary cultures of neurons from mouse cerebral cortex2006
- Author(s)
  T. Fujita, A. Shimada, N. Okada and A. Yamamoto
- Journal Title
  
  Neurosci. Lett 393
  
  Pages : 216-221
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characteristics of H^+-dependent nicotinic acid transport in primary cultures of astrocytes from rat cerebral cortex2006
- Author(s)
  A. Shimada, Y. Nakagawa, H. Morishige, A. Yamamoto and T. Fujita
- Journal Title
  
  Neurosci. Lett 392
  
  Pages : 207-212
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Zn^<2+>-sensitive GABA transporter expressed in primary cultures of astrocytes from rat astrocytes2006
- Author(s)
  Q. Wu, M. Wada, A. Shimada, N. Okada, A. Yamamoto and T. Fujita
- Journal Title
  
  Brain Res 1075
  
  Pages : 99-108
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional expression of metabotropic γ-aminobutyric acid GABA_B receptor in primary culture of astrocytes from rat cerebral cortex. Biochem. Biophys2006
- Author(s)
  M. Oka, M. Wada, Q. Wu, A. Yamamto and T. Fujita
- Journal Title
  
  Res. Commun 341
  
  Pages : 874-881
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93(in press)
- Data Source
  KAKENHI-PROJECT-16047229
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93
  
  Pages : 706-714
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93
  
  Pages : 706-714
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93
  
  Pages : 706-714
- Data Source
  KAKENHI-PROJECT-16047229
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93(in press)
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93(in press)
- Data Source
  KAKENHI-PROJECT-16015305
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : identification of the high-affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997(1)
  
  Pages : 52-61
- Data Source
  KAKENHI-PROJECT-16047229
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : Identification of the high affinity type H+/peptide transporter PEPT22004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997
  
  Pages : 52-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : identification of the high-affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997(1)
  
  Pages : 52-61
- Data Source
  KAKENHI-PROJECT-16015305
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : Identification of the high affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997
  
  Pages : 52-61
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : identification of the high-affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997(1)
  
  Pages : 52-61
- Data Source
  KAKENHI-PROJECT-15590143
[Presentation] 神経細胞におけるNa+,Cl－依存性エンケファリン輸送特性の検討2017
- Author(s)
  西村春香、松岡芹香、結城綾子、河野裕允、角本幹夫、藤田卓也
- Organizer
  医療薬学フォーラム2017・第25回クリニカルファーマシーシンポジウム
- Place of Presentation
  鹿児島市民文化ホール（鹿児島県鹿児島市）
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] HepG2 細胞での Na+ 依存性クエン酸輸送における金属イオンの影響2017
- Author(s)
  結城綾子、西村春香、後藤真耶、船橋理子、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2017・第25回クリニカルファーマシーシンポジウム
- Place of Presentation
  鹿児島市民文化ホール（鹿児島県鹿児島市）
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] 磁性リポプレックス導入によるRAW264細胞の免疫応答の変化の評価2016
- Author(s)
  合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場 (岐阜県岐阜市)
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] マグネタイトを導入したマクロファージにおけるサイトカイン産生能と細胞接着効率の評価2016
- Author(s)
  陣在ひと美、合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  びわ湖ホール (滋賀県大津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 細胞接着効率の向上を目的とした磁性マクロファージの作製とその機能評価2016
- Author(s)
  河野裕允、合ヶ坪芹香、藤田卓也
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ (静岡県静岡市)
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 腸管粘膜を標的とした磁性リポソームを利用した薬物・細胞デリバリーシステムの構築2016
- Author(s)
  河野裕允、藤田卓也
- Organizer
  遺伝子・デリバリー研究会第16回夏季セミナー
- Place of Presentation
  やすらぎ伊王島 (長崎県、長崎市)
- Year and Date
  2016-09-13
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] アミノ酸枯渇時のヒトアストロサイトにおけるsystem Aアミノ酸トランスポーターの適応調節機構2016
- Author(s)
  船橋理子、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  岐阜国際会議場（岐阜県岐阜市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] 細胞治療への応用を目的としたマクロファージに対する磁性体、遺伝子医薬品同時導入法の構築2016
- Author(s)
  中井健人、合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  びわ湖ホール (滋賀県大津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] Assessment of Intestinal Absorption of New Chemical Entities: In Vitro/In Vivo Correlation2015
- Author(s)
  T Fujita, Y Kono
- Organizer
  2015 AAPS Annual Meeting and Exposition
- Place of Presentation
  Orlando (USA)
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 消化管上皮細胞株 Caco-2 を用いた in vitro 薬物中枢移行評価系の構築2015
- Author(s)
  青野真実、河野裕允、藤田卓也
- Organizer
  第23回クリニカルファーマシーシンポジウム：医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] Effects of Surface Charge and PEG Modification of Liposomes on Their Uptake in Caco-2 Cells across Unstirred Water Layer2015
- Author(s)
  Y Kono, T Fujita
- Organizer
  2015 AAPS Annual Meeting and Exposition
- Place of Presentation
  Orlando (USA)
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] MDCK細胞におけるリポプレックスの細胞内取り込みに対する非撹拌水層の影響の評価2015
- Author(s)
  松岡健太、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] ヒトアストロサイトにおけるsystem Aアミノ酸トランスポーターの適応調節機構2015
- Author(s)
  船橋理子、河野裕允、藤田卓也
- Organizer
  第23回クリニカルファーマシーシンポジウム：医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] Assessment of Intestinal Absorption of New Chemical Entities: In Vitro/In Vivo Correlation.2015
- Author(s)
  Takua Fujita, Yusuke Kono
- Organizer
  Association of American Pharamceutical Sciences Annual Meeting and Exposition 2015
- Place of Presentation
  Orlando, Florida、USA
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] PEPT1を標的とした5-アミノサリチル酸プロドラッグの輸送特性の検討2015
- Author(s)
  由利龍嗣、西貴弘、河野裕允、寺田智祐、藤田卓也
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 5-アミノサリチル酸プロドラッグのCaco-2細胞における代謝特性の評価2015
- Author(s)
  岡田智文、由利龍嗣、河野裕允、寺田智祐、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] Caco-2細胞表面の非撹拌水層がリポプレックスの細胞内取り込みに及ぼす影響の評価2015
- Author(s)
  河野裕允、藤田卓也
- Organizer
  第31回日本DDS学会学術総会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 外部磁場に応答するマグネタイト封入マクロファージの作製とそのin vitroにおける機能評価2015
- Author(s)
  合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] DSSの暴露によるマクロファージのサイトカイン産生能の変化の評価2015
- Author(s)
  三好沙織、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 表面電荷の違いがリポソームの非撹拌水層拡散過程に及ぼす影響2015
- Author(s)
  岩崎亜侑、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 消化管上皮細胞株Caco-2を用いたin vitro薬物中枢移行評価系の構築2015
- Author(s)
  青野眞実、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] ヒト乳がん由来細胞MCF7におけるカルニチンの輸送機構に関する研究2015
- Author(s)
  地引麻維子、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 炎症時におけるヒト肝細胞様細胞HepaRGの薬物代謝特性の変動2015
- Author(s)
  片山紗希、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] Rifampicinによるヒト肝細胞様細胞HepaRGの薬物代謝・輸送系誘導の評価2015
- Author(s)
  後藤真耶、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] ヒト乳がん由来細胞 MCF7 におけるカルニチンの輸送機構に関する研究2015
- Author(s)
  地引麻維子、河野裕允、藤田卓也
- Organizer
  第23回クリニカルファーマシーシンポジウム：医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] アロマターゼ阻害剤の脳実質移行性の比較2012
- Author(s)
  楠原洋之、宮島真理、高橋佳代、高島忠之、細谷孝充、藤田卓也、渡辺恭良、杉山雄一
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] Intestinal active secretion of uric acid2011
- Author(s)
  Atsushi Hosomi, Kouji Ikukawa, Takeo Nakanishi, Takuya Fujita, Ikumi Tamai
- Organizer
  26^<th> JSSX Annual Meeting
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] Characterizing deteminning factors for brain exposure of aromatase inhibitors2011
- Author(s)
  Mari Miyajima, Hiroyuki Kusuhara, Kayo Tkahahashi, Takamitsu Hosoya, Tadayuki Takashima, Yasuyuki Watanabe, Takuya Fujita, John D. Schuetz, Yuichi Sugiyama
- Organizer
  26^<th> JSSX Annual Meeting
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] 各種動物種における薬物の消化管代謝の予測2011
- Author(s)
  守屋友加、藤田卓也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] ラット門脈-全身血同時採血法による薬物の消化管吸収性評価とP-glycoproteinの寄与2011
- Author(s)
  藤田卓也、守屋友加
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] Innovative strategies for drug development using microdosing clinical studies (NEDO microdose-PJ) 2011- (6)- Prediction of D2 receptor occupancy in the human brain by the recptor antagonists2011
- Author(s)
  Chunyong Wu, Hiroyuki Kusuhara, Takuya Fujita, Yuichi Sugiyama
- Organizer
  26^<th> JSSX Annual Meeting
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] Functional characterization of organic solute transporters in central nervous system2006
- Author(s)
  Takuya Fujita
- Organizer
  The 3^<rd> Korea-Japan Joint Symposium on Drug Delivery and Therapy
- Place of Presentation
  Seoul (Korea)
- Data Source
  KAKENHI-PROJECT-18390054

1. YAMAMOTO Akira (00166779)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
2. konishi satoshi (50288627)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
3. Kono Yusuke (60732823)

# of Collaborated Projects : 2results

# of Collaborated Products : 20results
4. KATSURA Toshiya (10283615)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 村西晶三 (60026888)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. 守屋友加 (00512295)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
7. 服部浩二 (60409670)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
8. Ganapathy Vadivel

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. Kusuhara Hiroyuki

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
10. 杉山雄一

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
11. 伊藤澄人

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 前田和哉

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 家入一郎

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

FUJITA Takuya 藤田 卓也

FUJITA-OKA Tkuya 岡 卓也(藤田 卓也)

岡 卓也 オカ タクヤ

Research Projects

Research Products

Co-Researchers

Physiological role of Na-dependent dicarboxylate transporters in central nervous systemPrincipal InvestigatorOngoing

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An openable tubular artificial gastrointestinal micromachine for medicine effect evaluation

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Development of magnetically guided M2 macrophages-based cell therapy for inflammatory bowel disease

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Biochemical properties of various organic ion transporters in central nervous systemPrincipal Investigator

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Biopharmaceutical Study on Organic Solute Transporters Which Modulate Central Nervous SystemPrincipal Investigator

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Biopharmaceutical Study on Organic Ions Transporters Which Act as Central Nervous System ModulatorsPrincipal Investigator

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脳の形成・発達に伴うタウリントランスポーターの発現変動と生理学的重要性Principal Investigator

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Review Section

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アストロサイトにおける代謝型GABA_B受容体の発現とGABA輸送体との機能的連関Principal Investigator

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Functional Linkage of Neutral amino acid transport system L and voltage-gated Ca^<2+> channels in central nervous systems.Principal Investigator

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Localization and functional regulation of H^+/oligopptide transporter(s) in brainPrincipal Investigator

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塩酸イリノテカン投与による消化管上皮細胞での薬物輸送担体の発現制御機構の解明Principal Investigator

Principal Investigator

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Functional modulation of drug efflux system by drug interaction and development of oral drug delivery system

Principal Investigator

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小腸上皮細胞における薬物の代謝およびそれに付随する消化管分泌機構Principal Investigator

Principal Investigator

FUJITA Takuya 藤田卓也

FUJITA-OKA Tkuya 岡卓也(藤田卓也)

岡卓也オカタクヤ