FUJITA Takuya 藤田卓也

… Alternative Names

FUJITA-OKA Tkuya 岡卓也(藤田卓也)

岡卓也オカタクヤ

藤田卓也フジタタクヤ

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Researcher Number	00247785
Other IDs
Affiliation (Current)	2025: 立命館大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2022: 立命館大学, 薬学部, 教授 2008: Ritsumeikan University, 薬学部, 教授 2007: Ritsumeikan University, 情報理工学部, 教授 2000 – 2006: 京都薬科大学, 薬学部, 助教授 1998 – 1999: 京都薬科大学, 薬学部, 講師 1995 – 1997: 京都薬科大学, 薬学部, 助手 1993: 京都薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Medical pharmacy / 応用薬理学・医療系薬学 / Biological Sciences / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator 応用薬理学・医療系薬学 / Physical pharmacy / Biomedical engineering/Biomaterial science and engineering / Physical pharmacy
Keywords	Principal Investigator アミノ酸トランスポーター / TCA回路中間体 / アストロサイト / 中枢神経系 / RT-PCR / Gabapentin / gabapentin / クエン酸回路 / クエン酸 / トランスポーター … More / ペプチドトランスポーター / PEPT2 / Caco-2 / クエン酸トランスポーター / クエン酸輸送 / cyclic GMP / 電位依存性Ca^<2+>チャンネル / H^+ exchanger / Na^+ / 電位依存性カルシウムチャネル / TCA回路 / ジ・トリカルボン酸トランスポーター / 有機イオントランスポーター / ニューロン / Transporter / 初代培養 / 薬物代謝 / Canavan病 / Na+依存性クエン酸トランスポーター / 血液脳関門（BBB） / 中枢移行性評価 / Na依存性ジ・トリカルボン酸トランスポーター / 肥満モデルマウス / 糖尿病 / SLC13A5 / 非アルコール性脂肪性肝炎 / 非アルコール性脂肪性肝疾患 / mammalian Indy (mIndy) / Na依存性ジカルボン酸トランスポーター / 薬物動態学 / 薬理学 / Na+依存性クエン酸輸送担体 / CREB / Na+共役クエン酸トランスポーター / 輸送活性調節機構 / 発現調節機構 / 神経細胞 / クエン酸回路中間体 / 中枢神経 / Nitric oxide synthase / Nitric oxide / Neurons / Astrocytes / Voltage-gated Ca^<2+> channels / Amino acids / α_2δ subunit / nitric oxide synthase / ヒトアストロサイト / マウス大脳皮質ニューロン / 中性アミノ酸輸送系システムL / Glial cells / voltage-gated Ca^<2+> channels / Amino acid transporters / Peptide transporter(s) / 過剰発現系 / RACE法 / PCR法 / 小脳 / peptide cotransporter / H^+ / アミノ酸トランスポータ / H^+exchanger / ペプチドトランスポータ / グリア細胞 / Na+共役型ジ･トリカルボン酸トランスポーター / エンケファリン輸送 / 初代培養神経細胞 / 初代培養神経 / ニューロペプチド / ジペプチドトランスポーター / 大脳皮質初代培養ニューロン / 再取り込み / 神経伝達物質 / コハク酸 / 免疫組織染色 / N-acetyl-L-aspartyl-L-glutamate / 有機イオン / 神経初代培養細胞 / アストロサイド / 脳・神経 / 遺伝子発現 / 薬物輸送 / 受容体 / 神経化学 / adenylylcyclase / Zn^<2+> / ラット大脳皮質アストロサイト / GABAトランスポーター / 代謝型GABA_B受容体 / 発現変動 / 大脳皮質ニューロン / タウリン / タウリントランスポーター / nitric oxide / brush-border membrane vesicle / 遅延性下痢 / 塩酸イリノテカン / Western 解析 / glycylsarcosine / synaptosomes / H^+oligopeptide transporter / キョートルフィン / ジ・トリペプチド / オリゴペプチドトランスポータ / 脳シナプトソーム / calcein-AM / p-aminobenzoic acid / cMOAT / ATP-binding cassette transporter / transporter / organic anion / P-glycoprotein / Caco-2細胞 / 有機アニオン / calcein / P糖タンパク質 / カルセイン / アミノ安息香酸 / 有機アニオン系薬物 / 薬物排泄機構 / 薬物消化管吸収 / 消化管吸収 / 胆汁酸塩 / プロテアーゼインヒビター / ペプチド性医薬品 … More Except Principal Investigator 吸収促進剤 / 膜抵抗 / タンパク分解酵素阻害剤 / 経肺吸収 / インスリン / 生理活性ペプチド / 炎症性腸疾患 / リポソーム / 磁場 / マクロファージ / M2型マクロファージ / 細胞送達システム / 磁場応答性リポソーム / 薬効評価 / 薬剤吸収評価 / マイクロマシン / ナノバイオシステム / Pharmaceutical excipient / Absorption enhancer / P-glycoprotein / Transporter / Drug efflux / Absorption enhancement / Oral administration / Gastrointestinal absorption / P糖タンパク / 製剤添加物 / P糖タンパク質 / トランスポーター / 薬物排出 / 吸収改善 / 経口投与 / 消化管吸収 / 培養細胞 / 肺組織 / アフリカツメガエル / ターゲッティング / 剤形修飾 / 高分子化修飾 / 肺吸収 / リンパ移行 / 抗癌剤 / 転移抑制 / 肺癌 Less

Pathophysiological role of Na+-dependent citrate transporter in central nervous systemPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Ritsumeikan University
Physiological role of Na-dependent dicarboxylate transporters in central nervous systemPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
An openable tubular artificial gastrointestinal micromachine for medicine effect evaluation
- Principal Investigator
  
  konishi satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Ritsumeikan University
Development of magnetically guided M2 macrophages-based cell therapy for inflammatory bowel disease
- Principal Investigator
  
  Kono Yusuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Ritsumeikan University
Biochemical properties of various organic ion transporters in central nervous systemPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Biopharmaceutical Study on Organic Solute Transporters Which Modulate Central Nervous SystemPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Biopharmaceutical Study on Organic Ions Transporters Which Act as Central Nervous System ModulatorsPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
  Kyoto Pharmaceutical University
脳の形成・発達に伴うタウリントランスポーターの発現変動と生理学的重要性Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
アストロサイトにおける代謝型GABA_B受容体の発現とGABA輸送体との機能的連関Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
Functional Linkage of Neutral amino acid transport system L and voltage-gated Ca^<2+> channels in central nervous systems.Principal Investigator
- Principal Investigator
 
 FUJITA Takuya
- Project Period (FY)
 2003 – 2004
- Research Category
 
 Grant-in-Aid for Scientific Research (C)
- Research Field
 
 Medical pharmacy
- Research Institution
 Kyoto Pharmaceutical University
Localization and functional regulation of H^+/oligopptide transporter(s) in brainPrincipal Investigator
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO PHARMACEUTICAL UNIVERSITY
塩酸イリノテカン投与による消化管上皮細胞での薬物輸送担体の発現制御機構の解明Principal Investigator
- Principal Investigator
  
  岡卓也 (藤田卓也)
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
Functional modulation of drug efflux system by drug interaction and development of oral drug delivery system
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
小腸上皮細胞における薬物の代謝およびそれに付随する消化管分泌機構Principal Investigator
- Principal Investigator
  
  岡卓也 (藤田卓也)
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Pharmaceutical University
脳におけるH^+-オリゴペプチドトランスポーターの局在と電気生理学的特性Principal Investigator
- Principal Investigator
  
  岡卓也 (藤田卓也)
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
小腸上皮細胞に存在する有機アニオン排出機構の実証と分子クローニングPrincipal Investigator
- Principal Investigator
  
  岡卓也 (藤田卓也)
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
肺培養上皮細胞系を用いた生理活性ペプチドの透過性の評価
- Principal Investigator
  
  山本昌
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
薬物の代謝・排泄器官として機能する消化管の生化学的解明Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
アフリカツメガエルの単離肺組織を用いた生理活性ペプチドの肺吸収性の評価
- Principal Investigator
  
  山本昌
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
脂肪酸および胆汁酸塩による薬物の上皮細胞透過性亢進機構の生化学的解明Principal Investigator
- Principal Investigator
  
  藤田卓也
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
肺癌の転移抑制を目的とした抗癌剤の高分子化修飾ならびに剤形修飾に関する研究
- Principal Investigator
  
  村西晶三
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Pharmaceutical University

[Book] Identity of thehigh-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter2006
- Author(s)
  V. Ganapathy and T. Fujita
- Publisher
  Adv ExpMed Biol
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Generation of Caco-2?cells with predictable metabolism by CYP3A4, UGT1A1 and CES using the PITCh system2023
- Author(s)
  Yamada Naoki、Negoro Ryosuke、Watanabe Keita、Fujita Takuya
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 50 Pages: 100497-100497
- DOI
  10.1016/j.dmpk.2023.100497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15264, KAKENHI-PROJECT-20K07190
[Journal Article] Inhibition of Liquid-Liquid Phase Separation for Breaking the Solubility Barrier of Amorphous Solid Dispersions to Improve Oral Absorption of Naftopidil2022
- Author(s)
  Fukiage Masafumi、Suzuki Kyosuke、Matsuda Maki、Nishida Yohei、Oikawa Michinori、Fujita Takuya、Kawakami Kohsaku
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 12 Pages: 2664-2664
- DOI
  10.3390/pharmaceutics14122664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Mesenchymal Stem Cells Promote IL-6 Secretion and Suppress the Gene Expression of Proinflammatory Cytokines in Contractile C2C12 Myotubes2022
- Author(s)
  Kono Yusuke、Kajita Hiroki、Okada Takuya、Nakagawa Rina、Fujita Takuya、Konishi Satoshi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 7 Pages: 962-967
- DOI
  10.1248/bpb.b22-00118
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Prediction of oral drug absorption in rats from in vitro data.2022
- Author(s)
  Yoshiyuki Akiyama, Naoya Matsumura, Asami Ono, Shun Hayashi, Satoko Funaki, Naomi Tamura, Takahiro Kimoto, Maiko Jiko, Yuka Haruna, Akiko Sarashina, Masahiro Ishida, Kotaro Nishiyama, Masahiro Fushimi, Yukiko Kojima, Takuya Fujita and Kiyohiko Sugano
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 39 Issue: 2 Pages: 359-373
- DOI
  10.1007/s11095-022-03173-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Generation of HepG2 Cells with High Expression of Multiple Drug-Metabolizing Enzymes for Drug Discovery Research Using a PITCh System2022
- Author(s)
  Negoro Ryosuke、Tasaka Mitsuki、Deguchi Sayaka、Takayama Kazuo、Fujita Takuya
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 10 Pages: 1677-1677
- DOI
  10.3390/cells11101677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Characterization of P-glycoprotein inhibitors for evaluating the effect of P-glycoprotein on the intestinal absorption of drugs.2021
- Author(s)
  Yusuke Kono, Iichiro Kawahara, Kohei Shinozaki, Ikuo Nomura, Honoka Marutani, Akira Yamamoto and Takuya Fujita
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 3 Pages: 338-338
- DOI
  10.3390/pharmaceutics13030388
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Indigo enhances wound healing activity of Caco-2 cells via activation of the aryl hydrocarbon receptor.2021
- Author(s)
  Takaaki Shimizu, Chisa Takagi, Toshinori Sawano, Yuto Eijima, Jin Nakatani, Takuya Fujita, and Hidekazu Tanaka
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 75 Issue: 4 Pages: 833-839
- DOI
  10.1007/s11418-021-01524-y
- NAID
  40022680495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Assessment of contribution of BCRP to intestinal absorption of various drugs using portal‐systemic blood concentration difference model in mice2020
- Author(s)
  Kawahara Iichiro、Nishikawa Satoyo、Yamamoto Akira、Kono Yusuke、Fujita Takuya
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 8 Issue: 1
- DOI
  10.1002/prp2.544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-17K15438
[Journal Article] Transport Characteristics of 5-Aminosalicylic Acid Derivatives Conjugated with Amino Acids via Human H+-Coupled Oligopeptide Transporter PEPT12020
- Author(s)
 Tatsushi Yuri, Yusuke Kono, Tomofumi Okada, Tomohiro Terada, Seiji Miyauchi, Takuya Fujita
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 43 Issue: 4 Pages: 697-706
- DOI
 10.1248/bpb.b19-01048
- NAID
 130007825299
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2020-04-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18K06608, KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-20K07190
[Journal Article] The Impact of Breast Cancer Resistance Protein (BCRP/ABCG2) on Drug Transport Across Caco-2 Cell Monolayers2020
- Author(s)
  Kawahara Iichiro、Nishikawa Satoyo、Yamamoto Akira、Kono Yusuke、Fujita Takuya
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 48 Issue: 6 Pages: 491-498
- DOI
  10.1124/dmd.119.088674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07190
[Journal Article] Hepatic Expression of the Na+-Coupled Citrate Transporter (NaCT/Slc13a5) and Cellular Uptake of Citrate in a Mouse Model of Type 1 Diabetes Induced by Streptozotocin2020
- Author(s)
 Goto Maya、Kono Yusuke、Ohno Kanta、Fujita Takuya
- Journal Title
 
 BPB Reports
 
 Volume: 3 Issue: 3 Pages: 97-101
- DOI
 10.1248/bpbreports.3.3_97
- NAID
 130007944882
- ISSN
 2434-432X
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-20K07190
[Journal Article] Transport characteristics of 5-aminosalicylic acid into colonic epithelium: Involvement of sodium-coupled monocarboxylate transporter SMCT1-mediated transport system2020
- Author(s)
  Yuri Tatsushi、Kono Yusuke、Fujita Takuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 3 Pages: 561-566
- DOI
  10.1016/j.bbrc.2020.01.139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-20K07190
[Journal Article] Protein Kinase C Regulates the Citrate Transport via Na+-Coupled Citrate Transporter NaCT in HepG2 Cells2019
- Author(s)
  Maya Goto、Yusuke Kono、Ayako Yuki、Haruka Nishimura、Mizuki Ikawa、Kanta Ohno、Takuya Fujita
- Journal Title
  
  BPB Reports
  
  Volume: 2 Pages: 134-140
- NAID
  130007940491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08430
[Journal Article] An Openable Artificial Intestinal Tract System Enables the Evaluation of Drug Absorption in Caco-2 Cells through the Reduction in Thickness of the Unstirred Water Layer2019
- Author(s)
  Yusuke Kono, Satoshi Konishi and Takuya Fujita
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 5 Pages: 840-844
- DOI
  10.1248/bpb.b18-00921
- NAID
  130007641451
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-05-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08430
[Journal Article] Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer.2018
- Author(s)
  Yusuke Kono, Ayu Iwasaki and Takuya Fujita
- Journal Title
  
  Pharmazie
  
  Volume: 73 Pages: 3-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08430
[Journal Article] Pharmaceutical stability of colloidal saccharated iron oxide injection in normal saline2018
- Author(s)
  Daiki Hira, Asami Suzuki, Yusuke Kono, Kosuke Shimokawa, Serika Matsuoka, Ken-yuh Hasumoto, Hiroyuki Kawahara, Masahide Onoue, Takuya Fujita, Tomonobu Okano and Mikio Kakumoto
- Journal Title
  
  J. Pharm. Health Care Sci.
  
  Volume: 4 Issue: 1 Pages: 1-6
- DOI
  10.1186/s40780-018-0116-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-17K15438, KAKENHI-PROJECT-17K15504
[Journal Article] Influence of Physicochemical Properties and PEG Modification of Magnetic Liposomes on Their Interaction with Intestinal Epithelial Caco-2 Cells2017
- Author(s)
  Yusuke Kono, Hitomi Jinzai, Yota Kotera and Takuya Fujita
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 12 Pages: 2166-2174
- DOI
  10.1248/bpb.b17-00563
- NAID
  130006235423
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-17K15438
[Journal Article] Pharmacokinetic Modeling and Monte Carlo Simulation to Predict Interindividual Variability in Human Exposure to Oseltamivir and Its Active Metabolite, Ro 64-0802.2017
- Author(s)
  Ito M, Kusuhara K, Ose A, Kondo T, Tanabe K, Nakayama H, Horita S, Fujita T, Sugiyama Y.
- Journal Title
  
  AAPS J
  
  Volume: 19 Issue: 1 Pages: 286-297
- DOI
  10.1208/s12248-016-9992-0
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-26293032, KAKENHI-PROJECT-26460210
[Journal Article] Development of magnetic anionic liposome/atelocollagen complexes for efficient magnetic drug targeting.2017
- Author(s)
  Yusuke Kono, Taketo Nakai, Hitomi Taguchi and Takuya Fujita
- Journal Title
  
  Drug Delivery
  
  Volume: 24 Issue: 1 Pages: 1740-1749
- DOI
  10.1080/10717544.2017.1402219
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-17K15438
[Journal Article] Dextran sodium sulfate alters cytokine production in macrophages in vitro2016
- Author(s)
  Y Kono, S Miyoshi, T Fujita
- Journal Title
  
  Pharmazie
  
  Volume: 71 Pages: 619-624
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18851
[Journal Article] Effect of Mechanical Agitation on Cationic Liposome Transport across an Unstirred Water Layer in Caco-2 Cells2016
- Author(s)
  Kono Y, Iwasaki A, Matsuoka K, Fujita T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 8 Pages: 1293-1299
- DOI
  10.1248/bpb.b16-00050
- NAID
  130005254677
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460210
[Journal Article] An openable artificial intestinal tract system for the in vitro evaluation of medicines.2015
- Author(s)
  Satoshi Konishi, Takuya Fujita, Koji Hattori, Yusuke Kono and Yoshifumi Matsushita
- Journal Title
  
  Microsystems &Nanoengineering
  
  Volume: 1 Issue: 1 Pages: 15015-15015
- DOI
  10.1038/micronano.2015.15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460210, KAKENHI-PROJECT-15K12526, KAKENHI-PROJECT-15K18851
[Journal Article] Studies on the Intestinal Absorption Characteristics of Sulfasalazine, a Breast Cancer Resistance Protein (BCRP) Substrate2013
- Author(s)
  Atsuko Tomaru, Nozomi Morimoto, Mariko Morishita, Kozo Takayama, Takuya Fujita, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 28 (1) Pages: 71-74
- NAID
  130004463289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Studies on the Intestinal Absorption Characteristics of Sulfasalazine, a Breast Cancer Resistance Protein (BCRP) Substrate2013
- Author(s)
  Atsuko Tomaru, Nozomi Morimoto, Mariko Morishita, Kozo Takayama, Takuya Fujita, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 28 Issue: 1 Pages: 71-74
- DOI
  10.2133/dmpk.DMPK-12-NT-024
- NAID
  130004463289
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Extra-renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG22012
- Author(s)
  Atsushi Hosomi, Takeo Nakanishi, Takuya Fujita, and Ikumi Tamai
- Journal Title
  
  PLoS ONE
  
  Volume: 7 (2)
- NAID
  120003959482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Pharmacokinetic interaction study of sulfasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP2012
- Author(s)
  Kusuhara H, et al
- Journal Title
  
  Br J Pharmacol
  
  Volume: (In press) Issue: 6 Pages: 1793-1803
- DOI
  10.1111/j.1476-5381.2012.01887.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23136101, KAKENHI-PROJECT-23590206, KAKENHI-PROJECT-24229002
[Journal Article] Extra-renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2.2012
- Author(s)
  Atsushi Hosomi, Takeo Nakanishi, Takuya Fujita, and Ikumi Tamai
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 2 Pages: e30456-e30456
- DOI
  10.1371/journal.pone.0030456
- NAID
  120003959482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Pharmacokinetic interaction study of sulfasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP2012
- Author(s)
  Hiroyuki Kusuhara, Hidetoshi Furuie, Akihiro Inano, Akihiro Sunagawa, Sakiko Yamada, Chungyong Wu, Shinya Fukizawa, Ichiro Ieiri, Mariko Morishita, Kiminobu Sumida, Hiroshi Mayahara, Takuya Fujita, Kazuya Maeda, and Yuichi Sugiyama
- Journal Title
  
  Br. J. Pharmacol
  
  Volume: 166 (6) Pages: 1793-1803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Intranasal immunization with poly(ɤ-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity2011
- Author(s)
  Keisuke Matsuo, Hayato Koizumi, Yumiko Ishii, Kazuhiko Matsuo, Takuya Fujita, Akira Yamamoto, Mitsuru Akashi, Shinsaku Nakagawa, and Naoki Okada
- Journal Title
  
  J Control. Rel
  
  Volume: 152 (2) Pages: 310-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Quantitative evaluation of the impact of active efflux by P-gp and Bcrp at the BBB on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as surrogate2011
- Author(s)
  Hiroshi Kodaira, Hiroyuki Kusuhara, Takuya Fujita, Junko Ushiki, Eiichi Fuse, and Yuichi Sugiyama
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume: 339 (3) Pages: 935-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Quantitative evaluation of the impact of active efflux by P-gp and Bcrp at the BBB on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as surrogate.2011
- Author(s)
  Hiroshi Kodaira, Hiroyuki Kusuhara, Takuya Fujita, Junko Ushiki, Eiichi Fuse, and Yuichi Sugiyama
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 339 Pages: 935-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590206
[Journal Article] Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein2008
- Author(s)
  K. Morimoto, M. Nakakariya, Y. Shirasaka, C. Kakinuma, T. Fujita I. Tamai and T. Ogihara
- Journal Title
  
  Drug Metab. Dispos 36
  
  Pages: 6-9
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization and cloning of amino acid transporter B^<0,+> (ATB^<0,+>) in primary cultured rat pneumocytes2008
- Author(s)
 T. Uchiyama, T. Fujita, H. J. Gukasyan, K. -J. Kim, Z. Borok, E. D. Crandall and V. H. L. Lee
- Journal Title
 
 J. Cell. Physiol 214
 
 Pages: 645-654
- Data Source
 KAKENHI-PROJECT-18390054
[Journal Article] P-glycoprotein restricts the penetration of Oseltamivir across the blood-brain barrier2008
- Author(s)
  A. Ose, H. Kusuhara, K. Yamatsugu, M. Kanai, M. Shibasaki, T. Fujita, A. Yamamoto and Y. Sugiyama
- Journal Title
  
  Drug Metab. Dispos 36
  
  Pages: 427-434
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Development of oligoarginine-drug conjugates linked to new peptidic self-cleavable spacers towards effective intestinal absorption2007
- Author(s)
  Y. Hayashi, K. Takayama, Y. Suehisa, T. Fujita, J.-T. Nguyen, S. Futaki, A. Yamamoto and Y. Kiso
- Journal Title
  
  Bioorg. Med. Chem Lett 17
  
  Pages: 5129-5132
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Na^+-independent choline transport in primary cultures of neurons from mouse cerebral cortex.2006
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Neuroscience Letters 393
  
  Pages: 216-221
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional expression of metabotropic γ-aminobutyric acid GABA_B receptor in primary culture of astrocytes from rat cerebral cortex. Biochem. Biophys2006
- Author(s)
  M. Oka, M. Wada, Q. Wu, A. Yamamto and T. Fujita
- Journal Title
  
  Res. Commun 341
  
  Pages: 874-881
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine2006
- Author(s)
  T. Ogihara, M. Kamiya, M. Ozawa, T. Fujita, A. Yamamoto, S. Yamashita, S. Ohnishi and Y. Isomura
- Journal Title
  
  Drug Metab. Pharmacokinet 21
  
  Pages: 238-244
- NAID
  130004933374
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter.2006
- Author(s)
  Vadivel Ganapathy, Takuya Fujita
- Journal Title
  
  Advanced Experimental Medicine and Biology 576
  
  Pages: 67-76
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional and molecular identification of sodium-coupled dicarboxylate transporters in primary cultured cerebrocortical astrocytes and neurons2006
- Author(s)
  E. Yodoya, M. Wada, A. Shimada, H. E. Yodoya, M. Wada, A. Shimada, H. Katsukawa, N. Okada, A. Yamamoto, V. Ganapathy and T. Fujita
- Journal Title
  
  J. Neurochem 97
  
  Pages: 162-173
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characteristics of H^+-dependent nicotinic acid transport in primary cultures of astrocytes from rat cerebral cortex2006
- Author(s)
  A. Shimada, Y. Nakagawa, H. Morishige, A. Yamamoto and T. Fujita
- Journal Title
  
  Neurosci. Lett 392
  
  Pages: 207-212
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Na^<+>-independent choline transport in primary cultures of neurons from mouse cerebral cortex2006
- Author(s)
 T. Fujita, A. Shimada, N. Okada and A. Yamamoto
- Journal Title
 
 Neurosci. Lett 393
 
 Pages: 216-221
- Data Source
 KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Zn^<2+>-sensitive GABA transporter expressed in primary cultures of astrocytes from rat astrocytes2006
- Author(s)
 Q. Wu, M. Wada, A. Shimada, N. Okada, A. Yamamoto and T. Fujita
- Journal Title
 
 Brain Res 1075
 
 Pages: 99-108
- Data Source
 KAKENHI-PROJECT-18390054
[Journal Article] Functional characterization of Na^+-coupled citrate transporter NaC2/NaCT expressed in primary cultures of neurons from mouse cerebral cortex2006
- Author(s)
  M. Wada, A. Shimada and T. Fujita
- Journal Title
  
  Brain Res 1081
  
  Pages: 92-100
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Functional expression of taurine transporter and its up-regulation in developing neurons from mouse cerebral cortex2006
- Author(s)
  T. Fujita, A. Shimada, M. Wada, S. Miyakawa and A. Yamamoto
- Journal Title
  
  Pharm. Res 23
  
  Pages: 689-696
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter2006
- Author(s)
  V. Ganapathy and T. Fujita
- Journal Title
  
  Adv ExpMed Biol 576
  
  Pages: 67-76
- Data Source
  KAKENHI-PROJECT-18390054
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93
  
  Pages: 706-714
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93(in press)
- Data Source
  KAKENHI-PROJECT-16015305
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93
  
  Pages: 706-714
- Data Source
  KAKENHI-PROJECT-16047229
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93(in press)
- Data Source
  KAKENHI-PROJECT-16047229
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : Involvement of sodium-coupled high affinity carboxylate transporter NaC3/NaDC3 mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93(in press)
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Transport characteristics of N-acetyl-L-aspartate in rat astrocytes : involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system.2005
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Journal of Neurochemistry 93
  
  Pages: 706-714
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : identification of the high-affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997(1)
  
  Pages: 52-61
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : Identification of the high affinity type H+/peptide transporter PEPT22004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997
  
  Pages: 52-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : Identification of the high affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997
  
  Pages: 52-61
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590143
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : identification of the high-affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997(1)
  
  Pages: 52-61
- Data Source
  KAKENHI-PROJECT-16015305
[Journal Article] Functional characterization of brain peptide transporter in rat cerebral cortex : identification of the high-affinity type H^+/peptide transporter PEPT2.2004
- Author(s)
  Takuya Fujita et al.
- Journal Title
  
  Brain Research 997(1)
  
  Pages: 52-61
- Data Source
  KAKENHI-PROJECT-16047229
[Presentation] サルBCRP-MDCK細胞を用いたサルBCRP基質認識特性の検討2023
- Author(s)
  伊藤健志、古澤李果、小林凌也、根来亮介、藤田卓也
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] 開閉可能なチューブデバイスを用いた薬物吸収および血管透過性評価系の構築2022
- Author(s)
  渡邉敬太、石橋伸悟、Abdalkader Rodi、小西聡、藤田卓也
- Organizer
  日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] ゲノム編集技術を用いて複数の薬物代謝酵素を安定発現した腸・肝細胞モデルの開発2022
- Author(s)
  根来亮介、出口清香、高山和雄、藤田卓也
- Organizer
  日本組織培養学会第94回大会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] PITChシステムを用いて複数の薬物代謝酵素を安定発現した腸・肝細胞モデルの開発2022
- Author(s)
  根来亮介、出口清香、高山和雄、藤田卓也
- Organizer
  日本薬物動態学会第37回年会大会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] 薬物の消化管吸収予測のための人工腸管マイクロマシンの開発2020
- Author(s)
  寺田圭佑、河野裕允、根来亮介、小西　聡、藤田卓也
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] マウス肝臓における核内受容体を介したSLC13A5の発現調節に関する検討2020
- Author(s)
  大野寛太、後藤　真耶、根来亮介、河野裕允、藤田卓也
- Organizer
  第70回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] 磁性リポソームを用いた間葉系幹細胞の磁性化とその骨格筋内保持効率の評価2020
- Author(s)
  河野裕允、宮本晃洋、根来亮介、藤田卓也
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] 骨格筋細胞に対する間葉系幹細胞の抗炎症効果のin vitro評価2020
- Author(s)
  宮本晃洋、河野裕允、根来亮介、藤田卓也
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] CRISPR-Cas9システムを用いたCYP3A4安定発現Caco-2細胞の作製2020
- Author(s)
  山田尚生、根来亮介、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07190
[Presentation] HepG2 細胞における Na+-dependent citrate transporter (SLC13A5) の PKC による輸送活性調節機構2019
- Author(s)
  後藤真耶、結城綾子、西村春香、河野裕允、藤田卓也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 骨格筋細胞 C2C12 における Na+ 非依存性中性アミノ酸トランスポーターの活性調節機構の解明2019
- Author(s)
  飯田千景、河野裕允、藤田卓也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 糖尿病発症時における Na+ 依存性クエン酸トランスポーターの発現変動に関する研究2019
- Author(s)
  原田千裕、後藤真耶、大野寛太、河野裕允、根来亮介、藤田卓也
- Organizer
  第69回日本薬学会関西支部総会大会
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] HepG2 細胞における cyclic AMP による Na+-dependent citrate transporter (SLC13A5) の発現上昇機構の解明2019
- Author(s)
  井川瑞貴、河野裕允、藤田卓也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] Transport Characteristics of Amino Acids-Conjugated 5-aminosalicylic Acid Derivatives via H+-Coupled Oligopeptide Transporter 12019
- Author(s)
  Tatsushi Yuri, Yusuke Kono, Tomohiro Terada, Takuya Fujita
- Organizer
  2019 AAPS Pharm Sci 360
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 外部磁場を利用した組織選択的細胞送達に向けた磁性化間葉系幹細胞の作製2018
- Author(s)
  大庭健、平岡芹菜、松田浩司、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 金属イオンによるNa+ 依存性クエン酸トランスポーターの輸送活性調節機構2018
- Author(s)
  西村春香、結城綾子、後藤真耶、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 異なる混合比からなる磁性負電荷リポソーム/アテロコラーゲン複合体の細胞内取り込み効率および免疫応答の評価2018
- Author(s)
  小寺陽太、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] HepG2細胞におけるNa+ 依存性クエン酸トランスポーターの活性調節機構2018
- Author(s)
  結城綾子、西村春香、後藤真耶、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] ドキソルビシン内封磁性負電荷リポソーム/アテロコラーゲン複合体のin vitro殺細胞効果の評価2018
- Author(s)
  田口ひとみ、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] ヒト網膜上皮ARPE-19細胞株におけるエンケファリン輸送活性の制御機構解析2018
- Author(s)
  松岡芹佳、西村春香、結城綾子、河野裕允、角本幹夫、藤田卓也
- Organizer
  医療薬学フォーラム2018／第26回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] In Vitro Devices for Estimating Intestinal Absorption of New Chemical Entities.2018
- Author(s)
  Takuya Fujita
- Organizer
  University British Colombia - Ritsumeikan University MEMS Workshop
- Invited
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 神経細胞におけるNa+,Cl－依存性エンケファリン輸送特性の検討2017
- Author(s)
  西村春香、松岡芹香、結城綾子、河野裕允、角本幹夫、藤田卓也
- Organizer
  医療薬学フォーラム2017・第25回クリニカルファーマシーシンポジウム
- Place of Presentation
  鹿児島市民文化ホール（鹿児島県鹿児島市）
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] Pharmacokinetic Study in Drug Delivery Stage.2017
- Author(s)
  Takuya Fujita
- Organizer
  University Hawaii - Ritsumeikan University Workshop
- Invited
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] HepG2 細胞での Na+ 依存性クエン酸輸送における金属イオンの影響2017
- Author(s)
  結城綾子、西村春香、後藤真耶、船橋理子、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2017・第25回クリニカルファーマシーシンポジウム
- Place of Presentation
  鹿児島市民文化ホール（鹿児島県鹿児島市）
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] HepG2細胞でのNa+依存性クエン酸輸送における金属イオンの影響2017
- Author(s)
  結城綾子、西村春香、後藤真耶、船橋理子、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2017／第25回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 神経細胞における Na+, Cl－依存性エンケファリン輸送特性の検討2017
- Author(s)
  西村春香、松岡芹佳、結城綾子、河野裕允、角本幹夫、藤田卓也
- Organizer
  医療薬学フォーラム2017／第25回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08430
[Presentation] 腸管粘膜を標的とした磁性リポソームを利用した薬物・細胞デリバリーシステムの構築2016
- Author(s)
  河野裕允、藤田卓也
- Organizer
  遺伝子・デリバリー研究会第16回夏季セミナー
- Place of Presentation
  やすらぎ伊王島 (長崎県、長崎市)
- Year and Date
  2016-09-13
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 細胞接着効率の向上を目的とした磁性マクロファージの作製とその機能評価2016
- Author(s)
  河野裕允、合ヶ坪芹香、藤田卓也
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ (静岡県静岡市)
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] マグネタイトを導入したマクロファージにおけるサイトカイン産生能と細胞接着効率の評価2016
- Author(s)
  陣在ひと美、合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  びわ湖ホール (滋賀県大津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 磁性リポプレックス導入によるRAW264細胞の免疫応答の変化の評価2016
- Author(s)
  合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場 (岐阜県岐阜市)
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] アミノ酸枯渇時のヒトアストロサイトにおけるsystem Aアミノ酸トランスポーターの適応調節機構2016
- Author(s)
  船橋理子、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  岐阜国際会議場（岐阜県岐阜市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] 細胞治療への応用を目的としたマクロファージに対する磁性体、遺伝子医薬品同時導入法の構築2016
- Author(s)
  中井健人、合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  びわ湖ホール (滋賀県大津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] ヒト乳がん由来細胞MCF7におけるカルニチンの輸送機構に関する研究2015
- Author(s)
  地引麻維子、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 消化管上皮細胞株 Caco-2 を用いた in vitro 薬物中枢移行評価系の構築2015
- Author(s)
  青野真実、河野裕允、藤田卓也
- Organizer
  第23回クリニカルファーマシーシンポジウム：医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] Rifampicinによるヒト肝細胞様細胞HepaRGの薬物代謝・輸送系誘導の評価2015
- Author(s)
  後藤真耶、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 5-アミノサリチル酸プロドラッグのCaco-2細胞における代謝特性の評価2015
- Author(s)
  岡田智文、由利龍嗣、河野裕允、寺田智祐、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] MDCK細胞におけるリポプレックスの細胞内取り込みに対する非撹拌水層の影響の評価2015
- Author(s)
  松岡健太、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] PEPT1を標的とした5-アミノサリチル酸プロドラッグの輸送特性の検討2015
- Author(s)
  由利龍嗣、西貴弘、河野裕允、寺田智祐、藤田卓也
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] ヒトアストロサイトにおけるsystem Aアミノ酸トランスポーターの適応調節機構2015
- Author(s)
  船橋理子、河野裕允、藤田卓也
- Organizer
  第23回クリニカルファーマシーシンポジウム：医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] 炎症時におけるヒト肝細胞様細胞HepaRGの薬物代謝特性の変動2015
- Author(s)
  片山紗希、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] Caco-2細胞表面の非撹拌水層がリポプレックスの細胞内取り込みに及ぼす影響の評価2015
- Author(s)
  河野裕允、藤田卓也
- Organizer
  第31回日本DDS学会学術総会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] Assessment of Intestinal Absorption of New Chemical Entities: In Vitro/In Vivo Correlation2015
- Author(s)
  T Fujita, Y Kono
- Organizer
  2015 AAPS Annual Meeting and Exposition
- Place of Presentation
  Orlando (USA)
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] ヒト乳がん由来細胞 MCF7 におけるカルニチンの輸送機構に関する研究2015
- Author(s)
  地引麻維子、河野裕允、藤田卓也
- Organizer
  第23回クリニカルファーマシーシンポジウム：医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-07-05
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] Assessment of Intestinal Absorption of New Chemical Entities: In Vitro/In Vivo Correlation.2015
- Author(s)
  Takua Fujita, Yusuke Kono
- Organizer
  Association of American Pharamceutical Sciences Annual Meeting and Exposition 2015
- Place of Presentation
  Orlando, Florida、USA
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460210
[Presentation] Effects of Surface Charge and PEG Modification of Liposomes on Their Uptake in Caco-2 Cells across Unstirred Water Layer2015
- Author(s)
  Y Kono, T Fujita
- Organizer
  2015 AAPS Annual Meeting and Exposition
- Place of Presentation
  Orlando (USA)
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 消化管上皮細胞株Caco-2を用いたin vitro薬物中枢移行評価系の構築2015
- Author(s)
  青野眞実、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 表面電荷の違いがリポソームの非撹拌水層拡散過程に及ぼす影響2015
- Author(s)
  岩崎亜侑、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム医療薬学フォーラム2015
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] 外部磁場に応答するマグネタイト封入マクロファージの作製とそのin vitroにおける機能評価2015
- Author(s)
  合ヶ坪芹香、河野裕允、藤田卓也
- Organizer
  第23回　クリニカルファーマシーシンポジウム
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] DSSの暴露によるマクロファージのサイトカイン産生能の変化の評価2015
- Author(s)
  三好沙織、河野裕允、藤田卓也
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K18851
[Presentation] アロマターゼ阻害剤の脳実質移行性の比較2012
- Author(s)
  楠原洋之、宮島真理、高橋佳代、高島忠之、細谷孝充、藤田卓也、渡辺恭良、杉山雄一
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] Intestinal active secretion of uric acid2011
- Author(s)
 Atsushi Hosomi, Kouji Ikukawa, Takeo Nakanishi, Takuya Fujita, Ikumi Tamai
- Organizer
 26^<th> JSSX Annual Meeting
- Place of Presentation
 Hiroshima, Japan
- Year and Date
 2011-11-16
- Data Source
 KAKENHI-PROJECT-23590206
[Presentation] 各種動物種における薬物の消化管代謝の予測2011
- Author(s)
  守屋友加、藤田卓也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] ラット門脈-全身血同時採血法による薬物の消化管吸収性評価とP-glycoproteinの寄与2011
- Author(s)
  藤田卓也、守屋友加
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-23590206
[Presentation] Innovative strategies for drug development using microdosing clinical studies (NEDO microdose-PJ) 2011- (6)- Prediction of D2 receptor occupancy in the human brain by the recptor antagonists2011
- Author(s)
 Chunyong Wu, Hiroyuki Kusuhara, Takuya Fujita, Yuichi Sugiyama
- Organizer
 26^<th> JSSX Annual Meeting
- Place of Presentation
 Hiroshima, Japan
- Year and Date
 2011-11-18
- Data Source
 KAKENHI-PROJECT-23590206
[Presentation] Characterizing deteminning factors for brain exposure of aromatase inhibitors2011
- Author(s)
 Mari Miyajima, Hiroyuki Kusuhara, Kayo Tkahahashi, Takamitsu Hosoya, Tadayuki Takashima, Yasuyuki Watanabe, Takuya Fujita, John D. Schuetz, Yuichi Sugiyama
- Organizer
 26^<th> JSSX Annual Meeting
- Place of Presentation
 Hiroshima, Japan
- Year and Date
 2011-11-16
- Data Source
 KAKENHI-PROJECT-23590206
[Presentation] Functional characterization of organic solute transporters in central nervous system2006
- Author(s)
 Takuya Fujita
- Organizer
 The 3^<rd> Korea-Japan Joint Symposium on Drug Delivery and Therapy
- Place of Presentation
 Seoul (Korea)
- Data Source
 KAKENHI-PROJECT-18390054

1. YAMAMOTO Akira (00166779)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. konishi satoshi (50288627)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Kono Yusuke (60732823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
4. KATSURA Toshiya (10283615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村西晶三 (60026888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 守屋友加 (00512295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 服部浩二 (60409670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Ganapathy Vadivel

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 杉山雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 伊藤澄人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 根来亮介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 楠原洋之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJITA Takuya 藤田 卓也

FUJITA-OKA Tkuya 岡 卓也(藤田 卓也)

岡 卓也 オカ タクヤ

藤田 卓也 フジタ タクヤ

Research Projects

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Co-Researchers

Pathophysiological role of Na+-dependent citrate transporter in central nervous systemPrincipal Investigator

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Physiological role of Na-dependent dicarboxylate transporters in central nervous systemPrincipal Investigator

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An openable tubular artificial gastrointestinal micromachine for medicine effect evaluation

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Development of magnetically guided M2 macrophages-based cell therapy for inflammatory bowel disease

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Biochemical properties of various organic ion transporters in central nervous systemPrincipal Investigator

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Biopharmaceutical Study on Organic Solute Transporters Which Modulate Central Nervous SystemPrincipal Investigator

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Biopharmaceutical Study on Organic Ions Transporters Which Act as Central Nervous System ModulatorsPrincipal Investigator

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脳の形成・発達に伴うタウリントランスポーターの発現変動と生理学的重要性Principal Investigator

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アストロサイトにおける代謝型GABA_B受容体の発現とGABA輸送体との機能的連関Principal Investigator

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Functional Linkage of Neutral amino acid transport system L and voltage-gated Ca^<2+> channels in central nervous systems.Principal Investigator

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Localization and functional regulation of H^+/oligopptide transporter(s) in brainPrincipal Investigator

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塩酸イリノテカン投与による消化管上皮細胞での薬物輸送担体の発現制御機構の解明Principal Investigator

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Functional modulation of drug efflux system by drug interaction and development of oral drug delivery system

FUJITA Takuya 藤田卓也

FUJITA-OKA Tkuya 岡卓也(藤田卓也)

岡卓也オカタクヤ

藤田卓也フジタタクヤ