Morimoto Yuji 森本裕二

… Alternative Names

MORIMOTO Yuji 森本裕二

森本裕二モリモトユウジ

Less

Researcher Number	00250457
Other IDs
Affiliation (Current)	2022: 北海道大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 北海道大学, 医学研究院, 教授 2016: 北海道大学, 医学研究科, 教授 2015: 北海道大学, 医学(系)研究科(研究院), 教授 2012 – 2013: 北海道大学, 医学(系)研究科(研究院), 教授 2010 – 2012: 北海道大学, 大学院・医学研究科, 教授 … More 2007: Hokkaido University, Graduate School of Medicine, Professor 2006: 北海道大学, 大学院医学研究科, 教授 2003 – 2005: 北海道大学, 大学院・医学研究科, 教授 2002: Hokkaido Univ., Grad. School of Med., Assistant Prof., 医学部附属病院, 講師 2000 – 2001: Hokkaido Univ., Grad.School of Med., Assistant Prof., 医学部・附属病院, 講師 1996 – 1999: 北海道大学, 医学部・附属病院, 助手 1993 – 1994: 北海道大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology Except Principal Investigator Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 脳虚血 / アポトーシス / 麻酔薬 / 神経細胞 / グルタミン酸 / 低体温 / イソフルラン / セボフルラン / バルビツレート / 幼弱脳 … More / 神経毒性 / 神経炎症 / サイトカイン / 敗血症 / 活性酸素 / カスペース / Hypothermia ; mild hypothermia / Barbiturate ; pentobarbital / Caspase / Reactive oxygen species / Cerebral ischemia / カルシウム / フローサイトメトリー / アシドーシス / 乳酸 / NG108-15 / 脳浮腫 / 興奮性アミノ酸 / ラット / 海馬切片 / 高速液体クロマトグラフィー / 神経系細胞 / PC12 cells / 細胞培養 / PC12 / ペントバルビタール / ベンゾジアゼピン / ミダゾラム / 吸入麻酔薬 / 全身麻酔の機序 / 超短パルスレーザー / 単層脂質幕 / 膜脂質流動性 / DPPC(Dipalmitoyl-L-α-Phosphatidylcholine) / 細胞膜 / 赤血球膜脂質 / 神経細胞死 / GABA / NMDA / 幼弱期 / 高二酸化炭素血症 / 麻醉薬 / 認知機能障害 / シナプス可塑性 / 敗血症関連脳症 / インターロイキン / 海馬 / 術後認知障害 / PC12細胞 / 軽度低体温 / Cell culture ; PC 12 cells / Cell death ; apoptosis / 初代神経細胞培養 / バルビタール / 神経細胞培養 / Cell culture ; cortical neuron / Cell death apoptosis / Glutamate ; glutamate neurotoxocity / Anesthesia / Neurotoxicity / 術後高次機能障害 / 認知症 / 麻酔 / 手術 / 高齢 / 認知機能 / 統合的ストレス応答 / 敗血症関連脳障害 / 認知機能低下 … More Except Principal Investigator メッセンジャーRNA / アフリカツメガエル / 卵母細胞 / 揮発性麻酔薬 / 受容体 Less

統合的ストレス応答が敗血症関連脳障害に果たす役割の解明Principal Investigator
- Principal Investigator
  
  森本裕二
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hokkaido University
Effect of anesthesia and surgery on postoperative cognitive dysfunction and dementia in senescence accelerated mousePrincipal Investigator
- Principal Investigator
  
  Morimoto Yuji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hokkaido University
Mechanism of postoperative cognitive dysfunction-Examination from neuroinflammationPrincipal Investigator
- Principal Investigator
  
  Morimoto Yuji
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Hokkaido University
Mechanism of neurotoxicity by anesthetics in the developing brain-Effect of hypercapniaPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Yuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
The neuronal toxicity of general anesthetics on the developing rat brainPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Yuji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
シナプス形成期における麻酔薬の神経毒性Principal Investigator
- Principal Investigator
  
  森本裕二
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
吸入麻酔薬の作用機序-超短パルスレーザーを用いた神経細胞膜の動的変化による解析Principal Investigator
- Principal Investigator
  
  森本裕二
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
Effect of mild hypothermia and barbiturate for cerebral ischemia-Evaluation by using primary neuronal culturePrincipal Investigator
- Principal Investigator
  
  MORIMOTO Yuji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  HOKKAIDO UNIVERSITY
Protective effect of mild hypothermia and barbiturate for cerebral ischemia-Evaluation by using neuronal cells-Principal Investigator
- Principal Investigator
  
  MORIMOTO Yuji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  HOKKAIDO UNIVERSITY
神経細胞のアポトーシスに及ぼす各種麻酔薬の影響Principal Investigator
- Principal Investigator
  
  森本裕二
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
脳虚血時の伝達物質放出と麻酔薬の抑制効果-海馬スライスを用いた解析-Principal Investigator
- Principal Investigator
  
  森本裕二
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
維代培養細胞を用いた虚血性神経細胞障害の機序及び各種薬物の保護的効果に関する検討-フローサイトメリ-法による解析-Principal Investigator
- Principal Investigator
  
  森本裕二
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
mRNA注入受容体発現モデルを用いた細胞内2次情報伝達系に対する麻酔薬の作用
- Principal Investigator
  
  太田善博
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University

All 2019 2017 2013 2012 2011 2010 2007

All Journal Article Presentation

[Journal Article] Minocycline prevents the impairment of hippocampal long-term potentiation in the septic mouse2017
- Author(s)
  Koji Hoshino, Mineji Hayakawa, Yuji Morimoto
- Journal Title
  
  Shock
  
  Volume: 印刷中
- NAID
  120006491490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462420
[Journal Article] Synapse-specific effects of IL-1beta; on long-term potentiation in the mouse hippocampus2017
- Author(s)
  Koji Hoshino, Kan Hasegawa, Haruyuk Kamiya, Yuji Morimoto
- Journal Title
  
  Biomedical Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462420
[Journal Article] Neonatalexposuretohighconcentrationofcarbondi oxideproducespersistentlearningdeficitswith impaired hippocampal synaptic plasticity2013
- Author(s)
  Kaori Tachibana, Toshikazu Hashimoto, Koichi Takita, Ryoko Ito, Rui Kato, Yuji Morimoto
- Journal Title
  
  Brain Research
  
  Volume: 1507 Pages: 83-90
- DOI
  10.1016/j.brainres.2013.02.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591699
[Journal Article] Neonatal administration with dexmedetomidine does not impair the rat hippocampal synaptic plasticity later in adulthood2012
- Author(s)
  Kaori Tachibana, Toshikazu Hashimoto, Rui Kato, Yosuke Uchida, Ryoko Ito, Koich Takita, Yuji Morimoto
- Journal Title
  
  Pediatric Anesthesia
  
  Volume: 22 Pages: 13-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591699
[Journal Article] Isoflurane bidirectionally modulates the paired-pulse responses in the rat hippocampal CA1 field in vivo.2007
- Author(s)
  Kaori Tachibana, Koichi Takita, Toshikazu Hashimoto, Machiko Matsumoto, Mitsuhiro Yoshioka and Yuji Morimoto
- Journal Title
  
  Anesthesia and Analgesia 105(4)
  
  Pages: 1006-1011
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591683
[Journal Article] Isoflurane bidirectionally modulates the paired-pulse responses in the rat hippocampal CA1 field in vivo2007
- Author(s)
  Kaori Tachibana, Koichi Takita, Toshikazu Hashimoto, Machiko Matsumoto, Mitsuhiro Yoshioka and Yuji Morimoto
- Journal Title
  
  Anesthesia and Analgesia 105(4)
  
  Pages: 1006-1011
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591683
[Presentation] Anesthesia Exposure as Well as Surgery Induces Neuroinflammation in Senescence-accelerated Prone Mouse 82019
- Author(s)
  Yuka Uchinami, Yosuke Uchida, Wang Wei, Koji Hoshino, Hitoshi Saito, Yuji Morimoto
- Organizer
  American Society of Anesthesiologists annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08843
[Presentation] ミノサイクリンは敗血症マウス海馬のシナプス可塑性低下を抑止する2017
- Author(s)
  干野晃嗣、森本裕二
- Organizer
  第44回日本集中治療医学会
- Place of Presentation
  ホテル札幌芸文館（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-25462420
[Presentation] 幼弱脳に対する麻酔薬の神経毒性:幼弱脳に対する麻酔薬の神経毒性-概論-2011
- Author(s)
  森本裕二
- Organizer
  日本麻酔科学会
- Place of Presentation
  ポートピアホテル(兵庫)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22591699
[Presentation] シンポジウム幼弱脳に対する麻酔薬の神経毒性:幼弱脳に対する麻酔薬の神経毒性-概論2011
- Author(s)
  森本裕二
- Organizer
  日本麻酔科学会学術集会
- Place of Presentation
  ポートピアホテル、神戸
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22591699
[Presentation] 麻酔薬は脳にとってフレネミーか?2010
- Author(s)
  森本裕二
- Organizer
  第56回日本麻酔科学会関西支部学術集会
- Place of Presentation
  大阪国際交流センター招待講演
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22591699
[Presentation] Isoflurane bidirectionally modulates the hippocampal paired-pulse responses in vivo.2007
- Author(s)
  Kaori Tachibana and Yuji Morimoto
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591683
[Presentation] 低濃度イソフルランはin vivoラット海馬CA1領域で短期シナプス可塑性を増強する2007
- Author(s)
  橘かおり, 橋本聡一, 森本裕二
- Organizer
  第54回日本麻酔科学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2007-05-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591683

1. TACHIBANA Kaori (50374468)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. TSURUGA Kenkichi (50399896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 干野晃嗣 (40802434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. WATANABE Satoshi (20292005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOSHIOKA Mitsuhiro (40182729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 太田善博 (00142802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 神谷温之 (10194979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 斉藤仁志 (10455694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 内田洋介 (00507585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HASEGAWA Kan

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Morimoto Yuji 森本 裕二

MORIMOTO Yuji 森本 裕二

森本 裕二 モリモト ユウジ

Research Projects

Research Products

Co-Researchers

統合的ストレス応答が敗血症関連脳障害に果たす役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of anesthesia and surgery on postoperative cognitive dysfunction and dementia in senescence accelerated mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of postoperative cognitive dysfunction-Examination from neuroinflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of neurotoxicity by anesthetics in the developing brain-Effect of hypercapniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The neuronal toxicity of general anesthetics on the developing rat brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シナプス形成期における麻酔薬の神経毒性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

吸入麻酔薬の作用機序-超短パルスレーザーを用いた神経細胞膜の動的変化による解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of mild hypothermia and barbiturate for cerebral ischemia-Evaluation by using primary neuronal culturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protective effect of mild hypothermia and barbiturate for cerebral ischemia-Evaluation by using neuronal cells-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経細胞のアポトーシスに及ぼす各種麻酔薬の影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳虚血時の伝達物質放出と麻酔薬の抑制効果-海馬スライスを用いた解析-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

維代培養細胞を用いた虚血性神経細胞障害の機序及び各種薬物の保護的効果に関する検討-フローサイトメリ-法による解析-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

mRNA注入受容体発現モデルを用いた細胞内2次情報伝達系に対する麻酔薬の作用

Principal Investigator

Morimoto Yuji 森本裕二

MORIMOTO Yuji 森本裕二

森本裕二モリモトユウジ