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HITOSHI OHISHI  大石 仁

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OHISHI Hitoshi  大石 仁

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Researcher Number 00252461
Affiliation (Current) 2025: 帝京科学大学, 医療科学部, 教授
Affiliation (based on the past Project Information) *help 2007 – 2013: Aichi Medical University, School of Medicine, Department of Anatomy, Associate Professor
2006: 愛知医科大学, 医学部, 助教授
1999 – 2000: 関西医科大学, 医学部, 講師
1996 – 1997: 京都大学, 医学部, 助手
1995 – 1996: 京都大学, 医学研究科, 助手
1994: 京都大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Nerve anatomy/Neuropathology
Except Principal Investigator
Nerve anatomy/Neuropathology / Pain science / Rehabilitation science/Welfare engineering / 疼痛学
Keywords
Principal Investigator
グルタミン酸受容体 / 免疫組織化学 / 抗体 / Receptor / G-protein / Striatum / 大脳基底核 / 受容体 / Gタンパク質 / 線条体 … More / 一次求心性線維 / 脊髄 / グルタミン酸 / 小脳 / ゴルジ細胞 / in situ hybridization / ラット / 中枢神経 … More
Except Principal Investigator
慢性痛 / GABA / 免疫組織 / グリア / 自律神経 / 筋障害 / 動物モデル / 痛み / glia / spinal cord / autonomic nervous system / molecular biology / immunohistochemistry / muscle damage / animal model / chronic pain / 脊髄 / 分子生物 / 筋傷害 / nociceptin / knockout mice / peptide receptor system / gene targeting / β-galactosidase / cDNAサブトラクション法 / イオンチャネル / 学習・記憶機構 / ノシセプチン / マウス / 遺伝子 / Olfactory system / Striatum / Cerebellum / Trigeminal system / Peptide / Glutamate receptor / Glycine / 逆行性標識法 / 免疫組織化学 / エンケファリン / オピオイド受容体 / 嗅覚 / 痛覚 / 三叉神経核 / P物質受容体 / セロトニン / 嗅覚系 / 線条体 / 小脳 / 三叉神経系 / ペプチド / グルタミン酸受容体 / グリシン / 予防 / 神経科学 / 運動療法 / 自発運動 / 不動化 / 分子生物学 / 免疫・炎症 Less
  • Research Projects

    (9 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (23 People)
  •  Development of exercise prescription for the prevention of chronic pain onset associated with hindlimb immobilization

    • Principal Investigator
      OHMICHI MIKA
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Aichi Medical University
  •  Exploration for the factors implicated in pathogenesis and maintenance of chronic pain.

    • Principal Investigator
      IWASE Satoshi, KUMAZAWA Takao (熊沢 孝朗)
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      疼痛学
    • Research Institution
      Aichi Medical University
  •  Systemic and molecular analysis on the pathology of newly-developed myopathic chronic pain models

    • Principal Investigator
      KUMAZAWA Takao
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pain science
    • Research Institution
      Aichi Medical University
  •  Nociceptin receptor-deficient mice : distribution of nociceptin precursor protein and receptor in brain and spinal cord

    • Principal Investigator
      SUGIMOTO Tetsuo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kansai Medical University
  •  ORPHAN G-PROTEIN COUPLED RECEPTORS IN THE STRIATUMPrincipal Investigator

    • Principal Investigator
      OHISHI Hitoshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kansai Medical University
  •  Gタンパク質結合型グルタミン酸受容体mGluR7の中枢神経系内分布の解析Principal Investigator

    • Principal Investigator
      大石 仁
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  Neuronal circuitry in relation with transmitters and their receptors

    • Principal Investigator
      MIZUNO Noboru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      KYOTO UNIVERSITY
  •  抗メタボトロピック グルタミン酸受容体抗体による小脳介在ニューロンの免疫組織化学Principal Investigator

    • Principal Investigator
      大石 仁
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  Gタンパク質結合型グルタミン酸受容体mGluR4,mGluR7の中枢神経系内分布Principal Investigator

    • Principal Investigator
      大石 仁
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University

All 2014 2013 2012 2009 2008

All Journal Article Presentation

  • [Journal Article] Activated spinal astrocytes are involved in the maintenance of chronic widespread mechanical hyperalgesia after cast immobilization.2014

    • Author(s)
      Mika Ohmichi
    • Journal Title

      Molecular Pain

      Volume: 24 Pages: 6-6

    • DOI

      10.1186/1744-8069-10-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23500628, KAKENHI-PROJECT-23590710, KAKENHI-PROJECT-24700565, KAKENHI-PROJECT-25750237, KAKENHI-PROJECT-25870884
  • [Journal Article] Two-week cast immobilization induced chronic widespread hyperalgesia in rats2012

    • Author(s)
      Ohmichi Y, Sato J, Ohmichi M, Sakurai H, Yoshimoto T, Morimoto A, Hashimoto T, Eguchi K, Nishihara M, Arai YC, Ohishi H, Asamoto K, Ushida T, Nakano T, Kumazawa T
    • Journal Title

      Eur J Pain

      Volume: 16 Issue: 3 Pages: 338-348

    • DOI

      10.1002/j.1532-2149.2011.00026.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500628
  • [Presentation] 脊髄アストロサイトの活性化はラット後肢のギプス固定後に出現する持続性の広範囲痛覚過敏に関与する2013

    • Author(s)
      大道裕介, 大道美香, 大石仁
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23500628
  • [Presentation] ギプス固定後慢性痛モデルラットの脊髄後角におけるc-Fosの両側性発現2012

    • Author(s)
      大石仁, 大道美香, 大道裕介
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2012-03-28
    • Data Source
      KAKENHI-PROJECT-23500628
  • [Presentation] ギプス固定後慢性痛モデルラットの脊髄後角におけるc-Fosの両側性発現2012

    • Author(s)
      大石仁
    • Organizer
      第177回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨
    • Data Source
      KAKENHI-PROJECT-23500628
  • [Presentation] ギプス固定後慢性痛モデルにおける機械的痛覚増強行動はMinocyclineにより減弱する2012

    • Author(s)
      大道美香, 大道裕介, 大石仁
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2012-03-28
    • Data Source
      KAKENHI-PROJECT-23500628
  • [Presentation] Inhibitory effects of minocycline, an inhibitor of spinal microglial activation, on widespread mechanical hyperalgesia in a rat model of cast immobilization2012

    • Author(s)
      Mika Ohmichi, Yusuke Ohmichi, Hitoshi Ohishi
    • Organizer
      14th World Congress on Pain
    • Place of Presentation
      Milan( Italy)
    • Year and Date
      2012-08-31
    • Data Source
      KAKENHI-PROJECT-23500628
  • [Presentation] 下肢ギプス固定がもたらす慢性的痛み行動に伴う脊髄ミクログリア・アストロサイトの変化2009

    • Author(s)
      大道裕介, 大道美香, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 江口国博, 山口佳子, 中野隆, 熊澤孝朗
    • Organizer
      第114回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20602009
  • [Presentation] Temporal and spatial changes of spinal glial cells in chronic pain model induced by the cast-immobilization.2008

    • Author(s)
      大道美香, 大道裕介, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 牛田享宏, 山口佳子, 熊澤孝朗
    • Organizer
      12th World Congress on Pain
    • Place of Presentation
      Glasgow
    • Data Source
      KAKENHI-PROJECT-20602009
  • [Presentation] Changes in pain behavior associated with the spinal glial activations in the chronic pain model by the plaster-immobilization.2008

    • Author(s)
      大道裕介, 大道美香, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 牛田享宏, 山口佳子, 熊澤孝朗
    • Organizer
      The 3rd Asian Pain Symposium
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-20602009
  • [Presentation] 下肢ギプス固定後に発症する慢性的痛み行動における脊髄グリア細胞の関与2008

    • Author(s)
      大道裕介, 大道美香, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 江口国博, 牛田享宏, 山口佳子, 熊澤孝朗
    • Organizer
      第23回日本整形外科学会基礎学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20602009
  • 1.  IWASE Satoshi (90184879)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  KUMAZAWA Takao (20022775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  OHMICHI MIKA (30581079)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 4.  OHMICHI Yusuke (50506673)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 5.  SAKURAI Hiroki (60454419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  EGUCHI Kunihiro (30113062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  USHIDA Takahiro (60304680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  KOZAKI Yasuko (20126882)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MIZUNO Noboru (10025596)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NOMURA Sakashi (60034188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TOKUNO Hironobu (40212071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKADA Masahiko (00236233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KANEKO Takeshi (90177519)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUGIMOTO Tetsuo (90144352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KASE Masahiko (10309221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HOUTANI Takeshi (60241163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SAKUMA Satoru (70309227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HONDA Takashi (20165608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  大迫 洋治 (40335922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  橋本 辰幸 (80367763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YOSHIMOTO Takahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 22.  YAMAGUCHI Yoshiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 23.  MORIMOTO Atsuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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