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HIRAI Yasuo  平井 康夫

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… Alternative Names

平井 康夫  ヒライ ヤスオ

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Researcher Number 00260076
Affiliation (based on the past Project Information) *help 2007: Japanese Foundation For Cancer Research, CANCER INSTITUTE, RESEARCH FELLOW
2005 – 2006: (財)癌研究会, 癌研究所細胞生物部, 研究員
2005: (財)癌研究会, 癌研究所・細胞生物部, 研究員
2004: 財団法人 癌研究会, 癌研究所・細胞生物部, 研究員
2001 – 2004: CANCER INSTITUTE, DEPT. OF CELL BIOLOGY, ASSOCIATE, 癌研究所・細胞生物部, 研究員 … More
2002: 癌研究会附属病院, 副部長
2001: 癌研究会, 附属病院, 副部長
2001: 財団法人 癌研究会, 癌研究所・細胞生物部, 研究員
2000: (財)癌研究会, 癌研究所・細胞生物部, 研究員
2000: 癌研究会, 附属病院・婦人科, 副部長
1999: 癌研究会附属病院, 婦人科, 医長
1999: 財団法人 癌研究会, 癌研究所・細胞生物部, 研究員
1999: CANCER INSTITUTE, JAPANESE FOUNDATION OF CANCER RESEARCH, RESEARCH FELLOW, 癌研究所・細胞生物部, 研究員
1998: 癌研究会, 癌研究所細胞生物部, 研究員
1998: 癌研究会附属病院, 医長
1997: 財団法人癌研究會, 癌研究所細胞生物部, 研究員
1994: (財)癌研究所, 細胞生物部, 研究員 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences
Except Principal Investigator
Obstetrics and gynecology / Biological Sciences
Keywords
Principal Investigator
PTEN / 遺伝的不安定性 / BAX / array-based CGH / 子宮頚部腺癌 / MICROSATELLITE INSTABILITY / TGFβRII / DCC(18q21.3) / 子宮頸部腺癌 / conventional CGH … More / 子宮内膜腺癌 / MULTISTEP CARCINOGENESIS / COMPARATIVE GENOMIC INSTABILITY / CGH / 発癌過程 / β-catenin / 多段階発癌 / 子宮頚癌 / DAB2(5n13) / LRP 1B(2q 21.2) / genetic instability / Endometrial adenocarcinoma / Endocervical adenocarcinoma / MLH1 / P-cadherin / DAB2(5p13) / DAB2(5q13) / LRP1B(2q21.2) / HPV INFECTION / ARRAY-BASED CGH / CONVENTIONAL CGH / GLASSY CELL CARCINOMA / ENDOMETRIAL ADENOCARCINOMA / ENDOCERVICAL ADENOCARCINOMAS / TCF βtype II Recetpor / TCFβ typeII Receptor / HPV感染 / HIV感染 / すりガラス細胞癌 / CHROMOSOMAL IMBALANCE / TGF 13 RII / ENDOCERVICAL ADENQCARCINOMAS / SMAD / Comparative Genomic Hybridization法 / TGF-β Type II Receptor / スリガラス細胞癌 / 細胞遺伝学 / 頚部腺癌 / ENDOMETRIAL CARCINOMA / エストロゲンリセプター / 臨床病理学 / E2F / TGF β Rll / CGH(comparative genomic hybridisation) / OGH(comparative genomic hybridisation) / TFGβRII / 子宮体癌 / hMLH1遺伝子 / hMSH2遺伝子 / MMR遺伝子 / MSI / 家族性子宮内膜癌 / HNPCC / アムステルダムクライテリア / 子宮内膜癌 / がん抑制遺伝子 / 3次元培養 / 悪性転換 / HPV遺伝子 / 予備細胞 … More
Except Principal Investigator
コホート研究 / 子宮頚癌 / CIN / Gene expression profiling / gene expression array / Laser capture microdissection / Endometrial Cancer / 遣伝子発現解析 / 遺伝子発現解析 / 発現アレイ法 / マイクロダイセクション / 子宮体癌 / L2 / ワクチン / 子宮頸癌 / E6 / VLP抗体 / HPV抗体 / 中央病理診断 / パートナー数 / CMV抗体 / クラミジア抗体 / HLA / HPV / 子宮頸がん / ケース・コントロール研究 / ヒトパピローマウイルス(HPV) Less
  • Research Projects

    (9 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (18 People)
  •  分子疫学的手法を用いた我が国の家族性子宮内膜癌の病態解明と疫学Principal Investigator

    • Principal Investigator
      平井 康夫
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN UTERINE CANCER BASED ON MOLECULAR CYTOGENETIC STUDYPrincipal Investigator

    • Principal Investigator
      HIRAI Yasuo
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Japanese Foundation For Cancer Research
  •  EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN UTERINE ENDOCERVICAL AND ENDOMETRIAL ADENOCARCINOMAS BASED ON CYTOGENETIC STUDY OF MULTI- STEP CARCINOGENESISPrincipal Investigator

    • Principal Investigator
      HIRAI Yasuo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Gene expression profile of small endometrial cancer by using gene expression array and laser capture microdissection

    • Principal Investigator
      SUGIYAMA Yuko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  HPV感染と子宮頚部発がんに関するコホート研究

    • Principal Investigator
      吉川 裕之
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN ENDOCERVICAL ADENOCARCINOMA OF THE UTERUS BASED ON CYTOGENETIC MECHANISMS OF MULTI- STEP CARCINOGENESISPrincipal Investigator

    • Principal Investigator
      HIRAI Yasuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  HPV感染と子宮頚部発がんに関するコホート研究

    • Principal Investigator
      吉川 裕之
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  EXLPLOITATION OF NEW DIAGNOSTIC PROCEDURES OF HUMAN ENDOMETRIAL CANCERS IN RELATION TO CYTOGENETIC MECHANISMS OF MULTI-STEP CARCINOGENESIS ELUCIDATED WITH CGHPrincipal Investigator

    • Principal Investigator
      HIRAI Yasuo
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      JAPANESE FOUNDATION OF CANCER RESEARCH
  •  予備細胞培養系の3次元培養による子宮頚部多段階発癌過程の解析Principal Investigator

    • Principal Investigator
      平井 康夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research

All 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

  • [Journal Article] Molecular Epidemiological and Mutational Analysis of MMR Genes In Endometrial Cancer Patients With HNPCC-associated Familial Predisposition To Cancer2008

    • Author(s)
      Hirai Y,Banno K, et. al.
    • Journal Title

      Cancer Science (In Press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Banno K, et. al. molecular Epidemiological and Mutational Analysis of MMR Genes In Endometrial Cancer Patients With HNPCC-associated Familial Predisposition To Cancer2008

    • Author(s)
      Hirai Y
    • Journal Title

      Cancer Science (In Press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] A unique fibrous tumor of the ovary:fibrosarcoma or mitotically active cellular fibroma?2008

    • Author(s)
      Kaku S, Hirai Y, et. al.
    • Journal Title

      Anticancer Res. 27

      Pages: 4365-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] A unique fibrous tumor of the ovary:fibrosarcoma or mitotically active cellular fibroma?2007

    • Author(s)
      Kaku S, Hirai Y, et. al.
    • Journal Title

      Anticancer Res. 27

      Pages: 4365-4369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Treatment results of adjuvant chemotherapy after radical hysterectomy for intermediate- and high-risk stage IB-IIA cervical cancer2006

    • Author(s)
      Takeshima N, Umayahara K, Fujiwara K, Hirai Y, et al.
    • Journal Title

      Gynecol Oncol 103

      Pages: 618-22

    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Treatment results of adjuvant chemotherapy after radical hysterectomy for intermediate-and high-risk stage IB-IIA cervical cancer2006

    • Author(s)
      Takeshima N, Hirai Y, et. al.
    • Journal Title

      Gynecol Oncol. 103

      Pages: 618-22

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Mutational analysis of TP53 and p21 in familial and sporadic ovarian cancer in Japan2006

    • Author(s)
      Amikura T, Sekine M, Hirai Y, et al.
    • Journal Title

      Gynecol Oncol 100

      Pages: 365-71

    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Effectiveness of postoperative chemotherapy for para-aortic lymph node metastasis of endometrial cancer2006

    • Author(s)
      Takeshima N, Umayahara K, Fujiwara K, Hirai Y, et al.
    • Journal Title

      Gynecol Oncol 102

      Pages: 214-7

    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Lymph node metastasis in ovarian cancer : difference between serous and non-serous primary tumors2005

    • Author(s)
      Takeshima N, Hirai Y, Umayahara K, Fujiwara K, Takizawa K, Hasumi K
    • Journal Title

      Gynecol Oncol 99(2)

      Pages: 427-431

    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] Mutational analysis of the estrogen receptor-alpha gene in familial ovarian cancer2005

    • Author(s)
      Wu HJ, Hirai Y, Tanaka K, et al.
    • Journal Title

      J Obstet Gynaecol Res. 31(5)

      Pages: 375-383

    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] CA125 regression during neoadjuvant chemotherapy as an independent prognostic factor for survival in patients with advanced ovarian serous adenocarcinoma2005

    • Author(s)
      Tate S, Hirai Y, Takeshima N, Hasumi K.
    • Journal Title

      Gynecol Oncol 96(1)

      Pages: 143-149

    • Data Source
      KAKENHI-PROJECT-17591770
  • [Journal Article] CA125 regression during neoadjuvant chemotherapy as an independent prognostic factor for survival in patients with advanced ovarian serous adenocarcinoma2005

    • Author(s)
      Tate S, Hirai Y, Takeshima N, Hasumi K.
    • Journal Title

      Gynecol Oncol 96(1)

      Pages: 143-149

    • Data Source
      KAKENHI-PROJECT-17015045
  • [Journal Article] Conventional and array-based comparative genomic hybridization analyzes of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine cervix.2004

    • Author(s)
      Hirai Y, Kawamata Y, Takeshima N, Furuta R, Kitagawa T, Kawaguchi T, Hasumi K, Sugai S, Noda T.
    • Journal Title

      Int J Oncol. Apr;24(4)

      Pages: 977-986

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH2004

    • Author(s)
      Hirai Y
    • Journal Title

      Am J Obstet Gynecol 191

      Pages: 1173-1173

    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Conventional and array-based comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine2004

    • Author(s)
      Hirai Y
    • Journal Title

      Int J Oncol 24

      Pages: 977-977

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group.2004

    • Author(s)
      Hirai Y, Hasumi K, Onose R, Kuramoto H, Kuzuya K, Hatae M, Ochiai K, Nozawa S, Noda K.
    • Journal Title

      Gynecol Oncol. Aug;94(2)

      Pages: 471-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group2004

    • Author(s)
      Hirai Y
    • Journal Title

      Gynecol Oncol 94

      Pages: 471-471

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH.2004

    • Author(s)
      Hirai Y, Utsugi K, Takeshima N, Kawamata Y, Furuta R, Kitagawa T, Kawaguchi T, Hasumi K, Noda T.
    • Journal Title

      Am J Obstet Gynecol., Erratum in : Am J Obstet Gynecol. Noda, Shirahama Tetsuo [corrected to Noda, Tetsuo]. Oct;191(4), Apr;192(4)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Putative gene loci associated with carciongenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH2004

    • Author(s)
      Hirai Y
    • Journal Title

      Am J Obstet Gynecol 191

      Pages: 1173-1173

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH.2004

    • Author(s)
      Hirai Y, et al.
    • Journal Title

      Am J Obstet Gynecol. 191(4)

      Pages: 1173-1182

    • Data Source
      KAKENHI-PROJECT-12218102
  • [Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group2004

    • Author(s)
      Hirai Y, Hasumi K, Onose R, Kuramoto H, Kuzuya K, Hatae M, Ochiai K, Nozawa S, Noda K.
    • Journal Title

      Gynecol Oncol 94(2)

      Pages: 471-476

    • Data Source
      KAKENHI-PROJECT-17015045
  • [Journal Article] A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched to same-patient normal tissue.2003

    • Author(s)
      Sugiyama Y, Dan S, Yoshida Y, Akiyama F, Sugiyama K, Hirai Y, Matsuura M, Miyata S, Ushijima M, Hasumi K, Yamori T.
    • Journal Title

      Clin Cancer Res. Nov15:9(15)

      Pages: 5589-5600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched same-patient2003

    • Author(s)
      Sugiyama Y, Hirai Y
    • Journal Title

      Clin Cancer Res 15

      Pages: 5589-5589

    • Data Source
      KAKENHI-PROJECT-14571599
  • [Journal Article] A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched to same-patent2003

    • Author(s)
      Sugiyama Y, Hirai Y
    • Journal Title

      Clin Cancer Res 15

      Pages: 5589-5589

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571599
  • [Presentation] 子宮頸部腺癌のComparative genomic hybridizationによる遺伝手解析2007

    • Author(s)
      平井 康夫, et. al.
    • Organizer
      日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-09-04
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Presentation] 子宮頚部腺癌のComparative genomic hybridizationによる遺伝子解析2007

    • Author(s)
      平井康夫、竹島信宏, et. al.
    • Organizer
      日本癌学会総会
    • Place of Presentation
      京都
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591770
  • [Presentation] Takeshima N, et. al. Gene Loci Associated with Carcinogenesis and Metastasis of Endocervical Determined by CGH2007

    • Author(s)
      Hirai Y
    • Organizer
      The Japanese Cancer Association
    • Place of Presentation
      In Kyoto
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591770
  • 1.  HASUMI Katsuhiko (70134608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  吉川 裕之 (40158415)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  神田 忠仁 (60134615)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  星合 昊 (50111290)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  岩坂 剛 (60117067)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  野田 哲生 (10183550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  清水 弘之 (90073139)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  佐藤 信二 (10142960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  八重樫 伸生 (00241597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  関谷 宗英 (00092065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  藤井 多久磨 (10218969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  金澤 浩二 (50092680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  永田 知里 (30283295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  阪埜 浩司 (70265875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  宇田川 康博 (80118918)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  鈴木 光明 (50110870)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  菅野 康吉 (00171124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SUGIYAMA Yuko (80322634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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