HIRAI Yasuo 平井康夫

Researcher Number	00260076
Affiliation *help	2011 : 東京女子医科大学, 医学部, 准教授 1997 – 2007 : 癌研究会, 研究員 2007 : Japanese Foundation For Cancer Research, CANCER INSTITUTE, RESEARCH FELLOW 2005 – 2006 : (財)癌研究会, 癌研究所細胞生物部, 研究員 2005 : (財)癌研究会, 癌研究所・細胞生物部, 研究員 … More
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences Except Principal Investigator Obstetrics and gynecology / Biological Sciences
Keywords	Principal Investigator PTEN / BAX / 遺伝的不安定性 / 子宮頚部腺癌 / MICROSATELLITE INSTABILITY / TGFβRII / array-based CGH / β-catenin / DCC(18q21.3) / 多段階発癌 … More Except Principal Investigator コホート研究 / 子宮頚癌 / CIN / 中央病理診断 / ヒトパピローマウイルス(HPV) / ワクチン / 発現アレイ法 / CMV抗体 / Gene expression profiling / gene expression array / マイクロダイセクション / ケース・コントロール研究 / 子宮頸癌 / 遣伝子発現解析 / E6 / VLP抗体 / 遺伝子発現解析 / HPV / 子宮体癌 / L2 / Endometrial Cancer / パートナー数 / HPV抗体 / 子宮頸がん / Laser capture microdissection / クラミジア抗体 / HLA Less

分子疫学的手法を用いた我が国の家族性子宮内膜癌の病態解明と疫学Principal Investigator
- Principal Investigator
  
  平井康夫
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN UTERINE CANCER BASED ON MOLECULAR CYTOGENETIC STUDYPrincipal Investigator
- Principal Investigator
  
  HIRAI Yasuo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Japanese Foundation For Cancer Research
EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN UTERINE ENDOCERVICAL AND ENDOMETRIAL ADENOCARCINOMAS BASED ON CYTOGENETIC STUDY OF MULTI- STEP CARCINOGENESISPrincipal Investigator
- Principal Investigator
  
  HIRAI Yasuo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Japanese Foundation For Cancer Research
Gene expression profile of small endometrial cancer by using gene expression array and laser capture microdissection
- Principal Investigator
  
  SUGIYAMA Yuko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Japanese Foundation for Cancer Research
HPV感染と子宮頚部発がんに関するコホート研究
- Principal Investigator
  
  吉川裕之
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN ENDOCERVICAL ADENOCARCINOMA OF THE UTERUS BASED ON CYTOGENETIC MECHANISMS OF MULTI- STEP CARCINOGENESISPrincipal Investigator
- Principal Investigator
  
  HIRAI Yasuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Japanese Foundation for Cancer Research
HPV感染と子宮頚部発がんに関するコホート研究
- Principal Investigator
  
  吉川裕之
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
EXLPLOITATION OF NEW DIAGNOSTIC PROCEDURES OF HUMAN ENDOMETRIAL CANCERS IN RELATION TO CYTOGENETIC MECHANISMS OF MULTI-STEP CARCINOGENESIS ELUCIDATED WITH CGHPrincipal Investigator
- Principal Investigator
  
  HIRAI Yasuo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  JAPANESE FOUNDATION OF CANCER RESEARCH
予備細胞培養系の3次元培養による子宮頚部多段階発癌過程の解析Principal Investigator
- Principal Investigator
  
  平井康夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research

All 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Banno K, et. al. molecular Epidemiological and Mutational Analysis of MMR Genes In Endometrial Cancer Patients With HNPCC-associated Familial Predisposition To Cancer2008
- Author(s)
  Hirai Y
- Journal Title
  
  Cancer Science (In Press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] A unique fibrous tumor of the ovary:fibrosarcoma or mitotically active cellular fibroma?2008
- Author(s)
  Kaku S, Hirai Y, et. al.
- Journal Title
  
  Anticancer Res. 27
  
  Pages : 4365-9
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Molecular Epidemiological and Mutational Analysis of MMR Genes In Endometrial Cancer Patients With HNPCC-associated Familial Predisposition To Cancer2008
- Author(s)
  Hirai Y,Banno K, et. al.
- Journal Title
  
  Cancer Science (In Press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] A unique fibrous tumor of the ovary:fibrosarcoma or mitotically active cellular fibroma?2007
- Author(s)
  Kaku S, Hirai Y, et. al.
- Journal Title
  
  Anticancer Res. 27
  
  Pages : 4365-4369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Treatment results of adjuvant chemotherapy after radical hysterectomy for intermediate- and high-risk stage IB-IIA cervical cancer2006
- Author(s)
  Takeshima N, Umayahara K, Fujiwara K, Hirai Y, et al.
- Journal Title
  
  Gynecol Oncol 103
  
  Pages : 618-22
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Effectiveness of postoperative chemotherapy for para-aortic lymph node metastasis of endometrial cancer2006
- Author(s)
  Takeshima N, Umayahara K, Fujiwara K, Hirai Y, et al.
- Journal Title
  
  Gynecol Oncol 102
  
  Pages : 214-7
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Mutational analysis of TP53 and p21 in familial and sporadic ovarian cancer in Japan2006
- Author(s)
  Amikura T, Sekine M, Hirai Y, et al.
- Journal Title
  
  Gynecol Oncol 100
  
  Pages : 365-71
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Treatment results of adjuvant chemotherapy after radical hysterectomy for intermediate-and high-risk stage IB-IIA cervical cancer2006
- Author(s)
  Takeshima N, Hirai Y, et. al.
- Journal Title
  
  Gynecol Oncol. 103
  
  Pages : 618-22
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Mutational analysis of the estrogen receptor-alpha gene in familial ovarian cancer2005
- Author(s)
  Wu HJ, Hirai Y, Tanaka K, et al.
- Journal Title
  
  J Obstet Gynaecol Res. 31(5)
  
  Pages : 375-383
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] CA125 regression during neoadjuvant chemotherapy as an independent prognostic factor for survival in patients with advanced ovarian serous adenocarcinoma2005
- Author(s)
  Tate S, Hirai Y, Takeshima N, Hasumi K.
- Journal Title
  
  Gynecol Oncol 96(1)
  
  Pages : 143-149
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] Lymph node metastasis in ovarian cancer : difference between serous and non-serous primary tumors2005
- Author(s)
  Takeshima N, Hirai Y, Umayahara K, Fujiwara K, Takizawa K, Hasumi K
- Journal Title
  
  Gynecol Oncol 99(2)
  
  Pages : 427-431
- Data Source
  KAKENHI-PROJECT-17591770
[Journal Article] CA125 regression during neoadjuvant chemotherapy as an independent prognostic factor for survival in patients with advanced ovarian serous adenocarcinoma2005
- Author(s)
  Tate S, Hirai Y, Takeshima N, Hasumi K.
- Journal Title
  
  Gynecol Oncol 96(1)
  
  Pages : 143-149
- Data Source
  KAKENHI-PROJECT-17015045
[Journal Article] Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH.2004
- Author(s)
  Hirai Y, et al.
- Journal Title
  
  Am J Obstet Gynecol. 191(4)
  
  Pages : 1173-1182
- Data Source
  KAKENHI-PROJECT-12218102
[Journal Article] Conventional and array-based comparative genomic hybridization analyzes of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine cervix.2004
- Author(s)
  Hirai Y, Kawamata Y, Takeshima N, Furuta R, Kitagawa T, Kawaguchi T, Hasumi K, Sugai S, Noda T.
- Journal Title
  
  Int J Oncol. Apr;24(4)
  
  Pages : 977-986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group.2004
- Author(s)
  Hirai Y, Hasumi K, Onose R, Kuramoto H, Kuzuya K, Hatae M, Ochiai K, Nozawa S, Noda K.
- Journal Title
  
  Gynecol Oncol. Aug;94(2)
  
  Pages : 471-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group2004
- Author(s)
  Hirai Y, Hasumi K, Onose R, Kuramoto H, Kuzuya K, Hatae M, Ochiai K, Nozawa S, Noda K.
- Journal Title
  
  Gynecol Oncol 94(2)
  
  Pages : 471-476
- Data Source
  KAKENHI-PROJECT-17015045
[Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group2004
- Author(s)
  Hirai Y
- Journal Title
  
  Gynecol Oncol 94
  
  Pages : 471-471
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Conventional and array-based comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine2004
- Author(s)
  Hirai Y
- Journal Title
  
  Int J Oncol 24
  
  Pages : 977-977
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH.2004
- Author(s)
  Hirai Y, Utsugi K, Takeshima N, Kawamata Y, Furuta R, Kitagawa T, Kawaguchi T, Hasumi K, Noda T.
- Journal Title
  
  Am J Obstet Gynecol., Erratum in : Am J Obstet Gynecol. Noda, Shirahama Tetsuo [corrected to Noda, Tetsuo]. Oct;191(4), Apr;192(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH2004
- Author(s)
  Hirai Y
- Journal Title
  
  Am J Obstet Gynecol 191
  
  Pages : 1173-1173
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Conventional and array-based comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine2004
- Author(s)
  Hirai Y
- Journal Title
  
  Int J Oncol 24
  
  Pages : 977-977
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Putative gene loci associated with carciongenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH2004
- Author(s)
  Hirai Y
- Journal Title
  
  Am J Obstet Gynecol 191
  
  Pages : 1173-1173
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] Phase II trial of 3-h infusion of paclitaxel in patients with adenocarcinoma of endometrium : Japanese Multicenter Study Group2004
- Author(s)
  Hirai Y
- Journal Title
  
  Gynecol Oncol 94
  
  Pages : 471-471
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched to same-patient normal tissue.2003
- Author(s)
  Sugiyama Y, Dan S, Yoshida Y, Akiyama F, Sugiyama K, Hirai Y, Matsuura M, Miyata S, Ushijima M, Hasumi K, Yamori T.
- Journal Title
  
  Clin Cancer Res. Nov15:9(15)
  
  Pages : 5589-5600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched same-patient2003
- Author(s)
  Sugiyama Y, Hirai Y
- Journal Title
  
  Clin Cancer Res 15
  
  Pages : 5589-5589
- Data Source
  KAKENHI-PROJECT-14571599
[Journal Article] A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched to same-patent2003
- Author(s)
  Sugiyama Y, Hirai Y
- Journal Title
  
  Clin Cancer Res 15
  
  Pages : 5589-5589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571599
[Presentation] 子宮頸部腺癌のComparative genomic hybridizationによる遺伝手解析2007
- Author(s)
  平井康夫, et. al.
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-09-04
- Data Source
  KAKENHI-PROJECT-17591770
[Presentation] 子宮頚部腺癌のComparative genomic hybridizationによる遺伝子解析2007
- Author(s)
  平井康夫、竹島信宏, et. al.
- Organizer
  日本癌学会総会
- Place of Presentation
  京都
- Year and Date
  2007-10-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591770
[Presentation] Takeshima N, et. al. Gene Loci Associated with Carcinogenesis and Metastasis of Endocervical Determined by CGH2007
- Author(s)
  Hirai Y
- Organizer
  The Japanese Cancer Association
- Place of Presentation
  In Kyoto
- Year and Date
  2007-10-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591770

1. 吉川裕之 (40158415)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
2. 神田忠仁 (60134615)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. 星合昊 (50111290)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
4. 岩坂剛 (60117067)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. HASUMI Katsuhiko (70134608)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. 清水弘之 (90073139)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 佐藤信二 (10142960)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 八重樫伸生 (00241597)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 関谷宗英 (00092065)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 藤井多久磨 (10218969)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 金澤浩二 (50092680)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 永田知里 (30283295)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 阪埜浩司 (70265875)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 宇田川康博 (80118918)

# of Collaborated Projects : 1results

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15. 鈴木光明 (50110870)

# of Collaborated Projects : 1results

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16. 菅野康吉 (00171124)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 野田哲生 (10183550)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. SUGIYAMA Yuko (80322634)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

HIRAI Yasuo 平井 康夫

Research Projects

Research Products

Co-Researchers

分子疫学的手法を用いた我が国の家族性子宮内膜癌の病態解明と疫学Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN UTERINE CANCER BASED ON MOLECULAR CYTOGENETIC STUDYPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN UTERINE ENDOCERVICAL AND ENDOMETRIAL ADENOCARCINOMAS BASED ON CYTOGENETIC STUDY OF MULTI- STEP CARCINOGENESISPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene expression profile of small endometrial cancer by using gene expression array and laser capture microdissection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HPV感染と子宮頚部発がんに関するコホート研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

EXPLOITATION OF NEW DIAGNO-THERAPEUTIC PROCEDURES OF HUMAN ENDOCERVICAL ADENOCARCINOMA OF THE UTERUS BASED ON CYTOGENETIC MECHANISMS OF MULTI- STEP CARCINOGENESISPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HPV感染と子宮頚部発がんに関するコホート研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

EXLPLOITATION OF NEW DIAGNOSTIC PROCEDURES OF HUMAN ENDOMETRIAL CANCERS IN RELATION TO CYTOGENETIC MECHANISMS OF MULTI-STEP CARCINOGENESIS ELUCIDATED WITH CGHPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

予備細胞培養系の3次元培養による子宮頚部多段階発癌過程の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Banno K, et. al. molecular Epidemiological and Mutational Analysis of MMR Genes In Endometrial Cancer Patients With HNPCC-associated Familial Predisposition To Cancer2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] A unique fibrous tumor of the ovary:fibrosarcoma or mitotically active cellular fibroma?2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Molecular Epidemiological and Mutational Analysis of MMR Genes In Endometrial Cancer Patients With HNPCC-associated Familial Predisposition To Cancer2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] A unique fibrous tumor of the ovary:fibrosarcoma or mitotically active cellular fibroma?2007

Author(s)

Journal Title

Data Source

[Journal Article] Treatment results of adjuvant chemotherapy after radical hysterectomy for intermediate- and high-risk stage IB-IIA cervical cancer2006

Author(s)

Journal Title

Data Source

[Journal Article] Effectiveness of postoperative chemotherapy for para-aortic lymph node metastasis of endometrial cancer2006

HIRAI Yasuo 平井康夫