Watanabe Daisuke 渡邉大介

… Alternative Names

渡邊大介ワタナベダイスケ

WATANABE Daisuke 渡邉大介

渡辺大介ワタナベダイスケ

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Researcher Number	00260175
Affiliation (Current)	2025: 北里大学, 理学部, 講師
Affiliation (based on the past Project Information) *help	2015 – 2024: 北里大学, 理学部, 講師 2007 – 2010: Kitasato University, Schod of Sci., Res. Assis 2007: 北里大学, 理学部, 専任講師 2004 – 2006: 北里大学, 理学部, 助手 1994: 財団法人大阪バイオサイエンス研究所, 第1研究部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Laboratory animal science / Developmental biology Except Principal Investigator Neurophysiology and muscle physiology / Laboratory animal science
Keywords	Principal Investigator コンディショナルノックアウトマウス / c-kit Sl 遺伝子 / inversin 遺伝子 / コンティショナルレスキュー法 / 疾患モデルマウス / 多発性嚢胞腎 / 左右軸形成 / Inv遺伝子 / 疾患モデル動物 / c-kit,　sl　遺伝子 … More / コンディショナルレスキュー法 / Sl 遺伝子 / c-kit 遺伝子 / Steel Factor/SF 遺伝子 / Kit Ligand 遺伝子 / Kit遺伝子 / Inv/Inversin 遺伝子 / model animal / transgenic mice / Inversin / transgenic rescue / c-kit / left/light asymmetry / cilia / polycystic kidney / inversin / conditional knockout / transgenic rescue mice / disease model animal / 幹細胞 / kit ligand / Inv/ inversin / コンティショナルレスキュー / 繊毛 / inv遺伝子 / コンディショナルレスキューマウス / コンデショナルノックアウトマウス / Inv 遺伝子 / トランスジェニックマウス / コンディシショナルレスキュー / コンディショナルノックアウト / 再生医療 / 発生分化 … More Except Principal Investigator DMD / Cre-loxP / 筋ジストロフィー / 筋肉 / マウス / アイソフォーム / 筋疾患 / ジストロフィン / Cre-lox / ES細胞 / Dp71 / vomeronasal nerve / olfactory sensory neuron / spermiogenesis / mdx / muscle / dystrophin isoforms / muscular dystrophy / 発生工学 / OEC / 嗅覚神経 / 精巣 / ジストロフィンアイソフォーム / Chromosomal Technology / regeneration / Muscle / Artificial Chromosome / ES cell / Muscular Dystrophy / 染色体工学 / 再生 / 人工染色体 / 幹細胞 / Notch3 / Lbx1 / サテライト細胞 / 筋再生 / 細胞死 / 変異体 / CTL / シグナル伝達 / 自己免疫疾患 / TNF / ジーン・ターゲッティング / Fasリガンド / 劇症肝炎 / サイトカイン / プロテアーゼ / Fas / DNase / ICAD / CAD / カスパーゼ / アポトーシス Less

Development and application of a novel conditional gene knockout mouse model without the use of embryonic stem cells.Principal Investigator
- Principal Investigator
  
  WATANABE DAISUKE
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kitasato University
Analysis of tissue- and development-specific gene function using a novel conditional-rescue transgenic mouse technique.Principal Investigator
- Principal Investigator
  
  wtanabe daisuke
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kitasato University
Analysis of Inv gene functions by generation of novel transgenic mice.Principal Investigator
- Principal Investigator
  
  Watanabe Daisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kitasato University
Functional analysis of muscle regeneration using gene-targeting and transgenic technologies
- Principal Investigator
  
  HANAOKA Kazunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kitasato University
Analysis of stem cell specific de novo methyltransferasesPrincipal Investigator
- Principal Investigator
  
  WATANABE Daisuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Kitasato University
Functional analysis of dystrophin isoforms using DMD-null mice
- Principal Investigator
  
  HANAOKA Kazunori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kitasato University
Production of animal models for Duchenne muscular dystrophy (DMD) using chromosomal manipulation and recombination
- Principal Investigator
  
  HANAOKA Kazunori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kitasato University
アポト-シスの分子機構とその生理作用
- Principal Investigator
  
  長田重一
- Project Period (FY)
  1994 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
  Osaka Bioscience Institute

[Journal Article] Generation of a conditional null allele of Lbx12010
- Author(s)
  Watanabe S, Matsushita S, Hayasaka M., Hanaoka K
- Journal Title
  
  Genesis
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500367
[Journal Article] Functional analysis of homeodomain-containing transcription factor,Lbx1,in satellite cells of mouse skeletal muscles.2007
- Author(s)
  Watanabe S, Kondo S and Hanaoka K
- Journal Title
  
  J.Cell Sci. 120
  
  Pages: 4178-4187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500320
[Journal Article] Functional analysis of homeodomain- containing transcription factor,Lbxl,in satellite cells of mouse skeletal muscles2007
- Author(s)
  Watanabe S, Kondo S and Hanaoka K
- Journal Title
  
  J.Cell Sci 33
  
  Pages: 4178-4187
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500320
[Journal Article] Functional analysis of homeodomain- containing transcription factor, Lbx1, in satellite cells of mouse skeletal muscles.2007
- Author(s)
  Watanabe, S, Kondo, S, Hanaoka, K
- Journal Title
  
  J. Cell Sci 120(23)
  
  Pages: 4178-4187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500320
[Journal Article] Transition of mouse de novo methyltransferases ecpression from Dnmt3b to Dmnt3a during neural progenitor cell development2006
- Author(s)
  D Watanabe, K Uchiyama, K Hanaokai
- Journal Title
  
  Neuroscience (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500279
[Journal Article] Transition of mouse de novo methytransferases expression from Dnmt3b to Dmnt3a during neural progenitor cell development2006
- Author(s)
  D Watanabe, K Uchiyama, K Hanaoka
- Journal Title
  
  Neuroscience 142
  
  Pages: 727-737
- Data Source
  KAKENHI-PROJECT-18500320
[Journal Article] Transition of mouse de novo methytransferases expression from Dnmt3b to Dmnt3a during neural progenitor cell development2006
- Author(s)
  D, Watanabe, K, Uchiyama, K, Hanaoka
- Journal Title
  
  Neuroscience 142
  
  Pages: 727-737
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500320
[Journal Article] Transition of mouse de novo methytransferases expression from Dnmt3b to Dmnt3a during neural progenitor cell development2006
- Author(s)
  Watanabe D, Uchiyama K and HanaokaK.
- Journal Title
  
  Dev.Biol 291
  
  Pages: 25-37
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500320
[Journal Article] A new model mouse for Duchenne muscular dystrophy produced by 2.4 megabase deletion of dystrophin gene using Cre-loxP recombination system2005
- Author(s)
  Watanabe D, Suetake I, Kakitani, A Ueda, M Hayasaka, K Tomizuka, K Hanaoka
- Journal Title
  
  Biochem.Biophys.Res.Communi. 328
  
  Pages: 507-516
- Data Source
  KAKENHI-PROJECT-16500279
[Journal Article] Expression of Dnmt3b in mouse hematopoietic progenitor cells and spermatogonia at specific stages2004
- Author(s)
  Watanabe D, Suetake I, Tajima S, Hanaoka K
- Journal Title
  
  Gene Expr Patterns 5
  
  Pages: 43-49
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500279
[Journal Article] Expression of Dnmt3b in mouse hematopoietic progenitor cells and spermatogonia at specific stages.2004
- Author(s)
  Watanabe D, Suetake I, Tajima S, Hanaoka K.
- Journal Title
  
  Gene Expr Patterns. 5 (1)
  
  Pages: 43-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500279
[Journal Article] Expression of Dnmt3b in mouse hematopoietic progenitor cells and spermatogonia at specific stages2004
- Author(s)
  Watanabe D, Suetake I, Tajima S, Hanaoka K.
- Journal Title
  
  Gene.Exp.Pattern 5
  
  Pages: 43-49
- Data Source
  KAKENHI-PROJECT-16500279
[Journal Article] Transition of mouse de novo methyltransferases expression from Dnmt3b to Dmnt3a during neural progenitor cell development
- Author(s)
  D Watanabe, K Uchiyama, K Hanaokai
- Journal Title
  
  Neuroscience (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500279
[Journal Article] Generation of a conditional null allele of Lbx1
- Author(s)
  Watanabe S, Matsushita S, Hayasaka M., Hanaoka K.
- Journal Title
  
  Genesis In press
- Data Source
  KAKENHI-PROJECT-20500367
[Presentation] コンディショナルレスキュー法ならびに特異的Cre遺伝子発現マウスをもちいた新規の実験手法の開発2025
- Author(s)
  渡邉大介
- Organizer
  文部科学省新学術領域研究「先端モデル動物支援」成果発表会
- Data Source
  KAKENHI-PROJECT-21K06002
[Presentation] Generation and analysis of conditional-rescue transgenic mice for c-Kit, Sl, and Inv genes.2024
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K06002
[Presentation] Development of novel conditional-rescue techniques for tissue-specific gene analysis.2023
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K06002
[Presentation] コンディショナルに遺伝子の欠失誘導を可能とする新たなトランスジェニックマウス系統の作成2022
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K06002
[Presentation] Generation of novel conditional-rescue transgenic mice target for the c-Kit receptor and its ligand gene.2021
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K06002
[Presentation] Generation of novel conditional-rescue transgenic mice target for the functional ligand and its receptor gene.2020
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06038
[Presentation] コンディショナルレスキュー法を用いた新規のトランスマウスの作成2020
- Author(s)
  渡邉大介
- Organizer
  文部科学省新学術領域研究　学術研究支援基盤形成先端モデル動物支援プラットフォーム
- Data Source
  KAKENHI-PROJECT-18K06038
[Presentation] Generation of the conditional-rescue transgenic mice that can regulate rescue-gene expression in the null mutant mice background.2019
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06038
[Presentation] Inv 遺伝子をターゲットとしたコンデショナルレスキューマウスの作製とその新技術の開発2018
- Author(s)
  渡邉大介
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06038
[Presentation] コンディショナルレスキュー法による組織特異的な遺伝子機能の組織特異的に特定の遺伝子機能の欠失を誘導するコンデショナルレスキューマウスの作製2017
- Author(s)
  櫻井瑛輝　伏見尚晃　花岡和則　渡辺大介
- Organizer
  生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K06808
[Presentation] Generation of conditional-rescue transgenic mice for tisusu-supecific expression of Inv gene2016
- Author(s)
  渡辺大介
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K06808
[Presentation] Development of conditional-rescue technique that can analyze tissue-specific gene functions2015
- Author(s)
  櫻井瑛輝 , 伏見尚晃 , 花岡和則 , 渡辺大介
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際展示場 (兵庫県　神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06808
[Presentation] Generation of mice withconditional null allele of Lbx1 gene2010
- Author(s)
  Watanabe S, Matsushita S, Hayasaka M, Hanaoka K
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20500367
[Presentation] Specific expressions of mouse denovo methyltransferases during stem cell differentiation2009
- Author(s)
  梅原芳惠, 坂本祐基, 花岡和則, 渡邉大介
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20500367
[Presentation] Expression dynamics of the imprinted transgenes during mouse germcell development2009
- Author(s)
  内山孝司、渡邉大介、早坂美智子、花岡和則
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20500367
[Presentation] non-coding RNA(Air)のES細胞分化における発現制御2008
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Place of Presentation
  兵庫県(神戸)
- Data Source
  KAKENHI-PROJECT-19570212
[Presentation] マウスIgf2r遺伝子のインプリンティングを制御するnon-coding RNA(Air)のプロモーター活性の可視化2008
- Author(s)
  渡邉大介
- Organizer
  日本エピジェネティク研究会
- Place of Presentation
  静岡県(三島)
- Data Source
  KAKENHI-PROJECT-19570212
[Presentation] non-coding RNA(Air)のES細胞分化における発現制御2008
- Author(s)
  渡邊大介
- Organizer
  日本エピジェネティク学会
- Place of Presentation
  静岡県(三島)
- Data Source
  KAKENHI-PROJECT-19570212
[Presentation] マウスIgf2r遺伝子のインプリンティングを制御するnon-coding RNA(Air)のプロモーター活性の可視化2008
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Place of Presentation
  兵庫県(神戸)
- Data Source
  KAKENHI-PROJECT-19570212
[Presentation] マウス幹細胞分化におけるdencvo methyltvanstevaseの局在と機能2007
- Author(s)
  宮本香織, 内山孝司, 花岡和剛, 渡辺大介
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19570212
[Presentation] マウス幹細胞分化におけるdenovo methyltransferaseの局在と機能2007
- Author(s)
  渡邉大介
- Organizer
  日本分子生物学会
- Place of Presentation
  神奈川県(横浜)
- Data Source
  KAKENHI-PROJECT-19570212
[Presentation] Coordinated expression of mouse de novo methyltransferases from Dnmt3b to Dnmt3a, during ES cell differentiation and olfactory neurogenesis2006
- Author(s)
  Watanabe, D, Uchiyama, K, Hanaoka, K
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500320
[Presentation] Coordinated expression of mouse de novo methyltransferases from Dnmt3b to Dnmt3a, during ES cell differentiation and olfactory neumgenesis2006
- Author(s)
  Watanabe D, Uchiyama K and Hanaoka K
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500320
[Presentation] A novel transgenic mouse line with the imprinted transgenes2006
- Author(s)
  内山孝司, 渡辺大介, 早坂美智子, 花岡和則
- Organizer
  日本発生生物学会第39回大会
- Place of Presentation
  京都
- Year and Date
  2006-06-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500320
[Presentation] 恒常的にsiRNAを発現するトランスジェニックマウスの作成及びその解析2006
- Author(s)
  上條裕貴, 渡辺大介, 花岡和則
- Organizer
  日本発生生物学会第39回大会
- Place of Presentation
  京都
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500320

1. HANAOKA Kazunori (40189577)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
2. UCHIYAMA Koji (20276174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. KITAMOTO Takero (20453516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 長田重一 (70114428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 福山英啓 (70303956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 福永理己郎 (40189965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 須田貴司 (70250090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 江成政人 (90294058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 田中正人 (00294059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 近藤亨 (30270573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MENO Chikara

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Watanabe Daisuke 渡邉 大介

渡邊 大介 ワタナベ ダイスケ

WATANABE Daisuke 渡邉 大介

渡辺 大介 ワタナベ ダイスケ

Research Projects

Research Products

Co-Researchers

Development and application of a novel conditional gene knockout mouse model without the use of embryonic stem cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of tissue- and development-specific gene function using a novel conditional-rescue transgenic mouse technique.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Inv gene functions by generation of novel transgenic mice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of muscle regeneration using gene-targeting and transgenic technologies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of stem cell specific de novo methyltransferasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of dystrophin isoforms using DMD-null mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Production of animal models for Duchenne muscular dystrophy (DMD) using chromosomal manipulation and recombination

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アポト-シスの分子機構とその生理作用

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Generation of a conditional null allele of Lbx12010

Author(s)

Journal Title

Data Source

[Journal Article] Functional analysis of homeodomain-containing transcription factor,Lbx1,in satellite cells of mouse skeletal muscles.2007

Author(s)

Journal Title

Data Source

[Journal Article] Functional analysis of homeodomain- containing transcription factor,Lbxl,in satellite cells of mouse skeletal muscles2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Functional analysis of homeodomain- containing transcription factor, Lbx1, in satellite cells of mouse skeletal muscles.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transition of mouse de novo methyltransferases ecpression from Dnmt3b to Dmnt3a during neural progenitor cell development2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transition of mouse de novo methytransferases expression from Dnmt3b to Dmnt3a during neural progenitor cell development2006

Author(s)

Journal Title

Watanabe Daisuke 渡邉大介

渡邊大介ワタナベダイスケ

WATANABE Daisuke 渡邉大介

渡辺大介ワタナベダイスケ