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Doh-ura Katsumi  堂浦 克美

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DOH-URA Katsumi  堂浦 克美

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Researcher Number 00263012
Other IDs
Affiliation (Current) 2025: 東北大学, 医学系研究科, 名誉教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 東北大学, 医学系研究科, 名誉教授
2016 – 2022: 東北大学, 医学系研究科, 教授
2011 – 2014: 東北大学, 医学(系)研究科(研究院), 教授
2012: 東北大学, 大学院・医学系研究科, 教授
2010: 東北大学, 大学院・医学系研究科, 教授 … More
2007 – 2008: Tohoku University, 大学院・医学系研究科, 教授
2006: 東北大学, 大学院医学系研究科, 教授
2004 – 2005: 東北大学, 医学部, 教授
2003 – 2004: Tohoku University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2001 – 2002: KYUSHU UNIV. Fac. medicne, 大学院・医学研究院, 助教授
2000: 九州大学, 大学院・医学研究院, 講師
1999: 九州大学, 大学院・医学系研究科, 講師 Less
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields / Pathology, Infection/Immunology, and related fields / Neurology / Cerebral neurosurgery / Nerve anatomy/Neuropathology / Biological Sciences
Except Principal Investigator
食の安全 / Psychiatric science / Virology
Keywords
Principal Investigator
プリオン / スクリーニング / プリオン病 / Aβ / 治療学 / 感受性 / 脳神経疾患 / drug screening / prophylactic and therapeutic medicine / 動物実験 … More / 薬剤スクリーニング / 予防治療薬 / 糖質 / 神経分子病態学 / アルツハイマー病 / 脳室内持続注入 / 持続感染培養細胞 / 構造活性相関 / プリオン産生阻害 / 高活性体 / 機序解明 / 免疫系 / セルロースエーテル / 細胞内分解系 / アルカリフォスファターゼ / ゲノムマーカー / gmfb / セルロース誘導体 / 防御機構 / プロテオミクス解析 / 遺伝子解析 / 病因論 / マイクロアレイ / ゲノム / 遺伝子 / in vivo assay / pharmacology / prion / amyloid / conformation disease / 表面プラスモン共鳴法 / 分子間相互作用解析 / in silicoスクリーニング / 作用機序 / in vitro実験 / 治療薬開発 / 薬理作用 / ベータ蛋白 / アミロイド / コンフォメーション病 / intracerebroventricular administration / pentsan polysulfate / animal experiment / persistently infected cell culture / inhibition of prion biosynthesis / prion disease / 脳内感染 / 脳室内投与 / ペントサン ポリサルフェート / エピゲノム / 宿主防御機構 / 神経病態免疫学 / 病態 / 治療 / アミロイド親和性化合物 / 神経病態生化学 / 複製増殖支援因子 / 感染細胞 / 構造変換 / 異常型プリオン蛋白 / RNA干渉 / 早期エンドゾーム / 包括的治療 / 公開講座 / トランスレーショナルリサーチ / 国際会議 / ペントサンポリサルフェート / 実験的治療 / クロイツフェルト・ヤコブ病 / 脳移行性 / アミロイド結合化合物 / プリオン蛋白沈着 / 核医学的診断法 / 円二色性スペクトル / 表面プラズモン共鳴 / 化学療法剤 … More
Except Principal Investigator
BSE / プリオン蛋白 / Diagnosis / 2d-electrophoresis / Serum Proteins / Scrapie / 尿 / タンパク質 / 血液診断 / 生前血液診断 / 血清中金属 / 血清中蛋白質 / スクレーピー / MAPT / Pick's disease / frontotemporal dementia / tau protein / prion protein / dementia / 分子生物学 / タウ遺伝子 / プリオン遺伝子 / ピック病 / 前頭側頭型痴呆 / タウ蛋白 / 痴呆 / 抗体 / 培養神経細胞 / 神経変異 / プリオン Less
  • Research Projects

    (17 results)
  • Research Products

    (327 results)
  • Co-Researchers

    (27 People)
  •  セルロースエーテルが関わるプリオンに対する生体防御機構の解明Principal Investigator

    • Principal Investigator
      堂浦 克美
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Exploration of a new principle for the elimination mechanism of abnormal proteinsPrincipal Investigator

    • Principal Investigator
      Doh-ura Katsumi
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tohoku University
  •  Identification of cellulose ether susceptibility genes involved in suppression of prion disease developmentPrincipal Investigator

    • Principal Investigator
      Doh-ura Katsumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Study for bringing a new dimension in the pathogenesis of prion disease.Principal Investigator

    • Principal Investigator
      Doh-ura katsumi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Pathology, Infection/Immunology, and related fields
    • Research Institution
      Tohoku University
  •  Analysis of host genetic factors associated with disease suppression against prion diseases.Principal Investigator

    • Principal Investigator
      Doh-ura Katsumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Elucidation of the epigenetic gene regulation related to the inhibition of prion formationPrincipal Investigator

    • Principal Investigator
      DOH-URA Katsumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Investigation on host defense mechanism and search for new therapeutic targets against prion diseasesPrincipal Investigator

    • Principal Investigator
      DOH-URA Katsumi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Research of therapeutic strategy applying to both prion diseases and Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      DOH-URA Katsumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  siRNAを用いた早期エンドゾーム中のプリオン複製補助因子の探索Principal Investigator

    • Principal Investigator
      堂浦 克美
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  ヤコブ病に対する実験的治療法に関する国際連絡会議の企画Principal Investigator

    • Principal Investigator
      堂浦 克美
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Analysis of Serum Proteins of Scrapie and BSE and Application to the Diagnosis.

    • Principal Investigator
      YOKOTA Hiroshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      食の安全
    • Research Institution
      Rakuno Gakuen University
  •  プリオン病の化学療法剤開発に関する研究Principal Investigator

    • Principal Investigator
      堂浦 克美
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  非通常病原体プリオンの分子機構

    • Principal Investigator
      片峰 茂
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Nagasaki University
  •  プリオン・バイオイメージング法開発に関する基礎研究Principal Investigator

    • Principal Investigator
      堂浦 克美
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tohoku University
      Kyushu University
  •  Development and pharmacological analysis of therapeutic drugs for conformation diseases and prion diseasesPrincipal Investigator

    • Principal Investigator
      DOH-URA Katsumi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
      Kyushu University
  •  Development of prophylactic and therapeutic anti-prion drugs for the patients at high risksPrincipal Investigator

    • Principal Investigator
      DOH-URA Katsumi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tohoku University
      Kyushu University
  •  Prion protein and tau protein gene analysis in frontotemporal dementia in Japan

    • Principal Investigator
      OGOMORI Koji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Kyushu University

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All Journal Article Presentation Book Patent

  • [Book] 脳科学研究の現状と課題 プリオン病研究の進歩(杉田秀夫、高橋清久編集)2003

    • Author(s)
      堂浦克美
    • Total Pages
      324
    • Publisher
      じほう社、東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Book] Advances in prion disease research. the topics and challenge of neuroscience research. (Eds.by Sugita H, Takahashi K.)(Jpn)2003

    • Author(s)
      Doh-ura K.
    • Total Pages
      324
    • Publisher
      Jiho, Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Combination of Styrylbenzoazole Compound and Hydroxypropyl Methylcellulose Enhances Therapeutic Effect in Prion-Infected Mice.2024

    • Author(s)
      Teruya K, Oguma A, Iwabuchi S, Nishizawa K, Doh-Ura K.
    • Journal Title

      Molecular Neurobiology

      Volume: 61(7) Issue: 7 Pages: 4705-4711

    • DOI

      10.1007/s12035-023-03852-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Journal Article] Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer’s disease2023

    • Author(s)
      Ali Tahir、Klein Antonia N.、McDonald Keegan、Johansson Lovisa、Mukherjee Priyanka Ganguli、Hallbeck Martin、Doh-ura Katsumi、Schatzl Hermann M.、Gilch Sabine
    • Journal Title

      Journal of Neuroinflammation

      Volume: 20(1) Issue: 1 Pages: 177-177

    • DOI

      10.1186/s12974-023-02858-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Journal Article] 治療法開発状況2023

    • Author(s)
      照屋健太、堂浦克美
    • Journal Title

      Clinical Neuroscience

      Volume: 41(9) Pages: 1240-1243

    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Journal Article] Anti-prion activity of cellulose ether is impaired in mice lacking pre T-cell antigen receptor α, T-cell receptor δ, or lytic granule function2022

    • Author(s)
      Teruya Kenta、Oguma Ayumi、Takahashi Satoko、Watanabe-Matsui Miki、Tsuji-Kawahara Sachiyo、Miyazawa Masaaki、Doh-ura Katsumi
    • Journal Title

      International Immunopharmacology

      Volume: 107 Pages: 108672-108672

    • DOI

      10.1016/j.intimp.2022.108672

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03481, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435, KAKENHI-PROJECT-23K24120, KAKENHI-PROJECT-23K24239
  • [Journal Article] プリオン病の薬物治療2022

    • Author(s)
      照屋健太、堂浦克美
    • Journal Title

      脳神経内科

      Volume: 97 Pages: 467-476

    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Journal Article] Therapeutic development of polymers for prion disease.2022

    • Author(s)
      Teruya K, Doh-ura K.
    • Journal Title

      Cell Tissue Res.

      Volume: in press. Issue: 1 Pages: 349-365

    • DOI

      10.1007/s00441-022-03604-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435, KAKENHI-PROJECT-23K05036, KAKENHI-PROJECT-23K24239
  • [Journal Article] Activities of curcumin-related compounds in two cell lines persistently infected with different prion strains2022

    • Author(s)
      Teruya Kenta、Iwabuchi Sara、Watanabe Yuki、Tsuchida Rikiya、Watanabe-Matsui Miki、Konno Hiroyuki、Doh-ura Katsumi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1866 Issue: 4 Pages: 130094-130094

    • DOI

      10.1016/j.bbagen.2022.130094

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435, KAKENHI-PROJECT-23K24239
  • [Journal Article] プリオン病の薬物治療2022

    • Author(s)
      照屋健太、堂浦克美
    • Journal Title

      脳神経内科

      Volume: 97 Pages: 467-476

    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Journal Article] Polymorphisms in glia maturation factor β gene are markers of cellulose ether effectiveness in prion-infected mice2021

    • Author(s)
      Teruya Kenta、Oguma Ayumi、Arai Keita、Nishizawa Keikoi、Sakasegawa Yuji、Schatzl Hermann、、Iwabuchi Sara、Watanabe-Matsui MikGilch Sabine、Doh-ura Katsumi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 560 Pages: 105-111

    • DOI

      10.1016/j.bbrc.2021.04.116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435
  • [Journal Article] Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics2021

    • Author(s)
      Ding Mingxuan、Teruya Kenta、Zhang Weiguanliu、Lee Hae Weon、Yuan Jue、Oguma Ayumi、Foutz Aaron、Camacho Manuel V.、Mitchell Marcus、Greenlee Justin J.、Kong Qingzhong、Doh-ura Katsumi、Cui Li、Zou Wen-Quan
    • Journal Title

      Molecular Neurobiology

      Volume: 58 Issue: 9 Pages: 4280-4292

    • DOI

      10.1007/s12035-021-02418-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435
  • [Journal Article] Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.2020

    • Author(s)
      Minikel EV, Zhao HT, Le J, O'Moore J, Pitstick R, Graffam S, Carlson GA, Kavanaugh MP, Kriz J, Kim JB, Ma J, Wille H, Aiken J, McKenzie D, Doh-ura K, Beck M, O'Keefe R, Stathopoulos J, Caron T, Schreiber SL, Carroll JB, Kordasiewicz HB, Cabin DE, Vallabh SM.
    • Journal Title

      Nucleic Acids Res.

      Volume: 48(19) Issue: 19 Pages: 10615-10631

    • DOI

      10.1093/nar/gkaa616

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Journal Article] Intermolecular crosslinking of abnormal prion protein is efficiently induced by a primuline-sensitized photoreaction2019

    • Author(s)
      Teruya Kenta、Nishizawa Keiko、Oguma Ayumi、Sakasegawa Yuji、Kitamoto Tetsuyuki、Doh-ura Katsumi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1863 Issue: 2 Pages: 384-394

    • DOI

      10.1016/j.bbagen.2018.11.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07518, KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-18H02738, KAKENHI-PROJECT-19K22479
  • [Journal Article] Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression.2019

    • Author(s)
      Hannaoui S, Arifin MI, Chang SC, Yu J, Gopalakrishnan P, Doh-ura K, Schatzl HM, Gilch S.
    • Journal Title

      J Neurochem.

      Volume: 152(6) Issue: 6 Pages: 727-740

    • DOI

      10.1111/jnc.14877

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-19H03570
  • [Journal Article] Combining autophagy stimulators and cellulose ethers for therapy against prion disease.2019

    • Author(s)
      Abdulrahman BA, Tahir W, Doh-ura K, Gilch S, Schatzl HM.
    • Journal Title

      Prion.

      Volume: (1) Issue: 1 Pages: 185-196

    • DOI

      10.1080/19336896.2019.1670928

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-19H03570
  • [Journal Article] Preparation and Characterization of Cellulose Ether Liposomes for the Inhibition of Prion Formation in Prion-infected Cells.2019

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Schatzl H, Gilch S, Doh-ura K.
    • Journal Title

      J Pharm Sci.

      Volume: - Issue: 8 Pages: 2814-2820

    • DOI

      10.1016/j.xphs.2019.03.025

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-18K07518, KAKENHI-PROJECT-19H03570
  • [Journal Article] Insights from Therapeutic Studies for PrP Prion Disease.2017

    • Author(s)
      Teruya K, Doh-ura K.
    • Journal Title

      Cold Spring Harb Perspect Med.

      Volume: 7(3) Issue: 3 Pages: a024430-a024430

    • DOI

      10.1101/cshperspect.a024430

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-15K01804
  • [Journal Article] プリオン病の多様性と治療開発2017

    • Author(s)
      逆瀬川 裕二、堂浦 克美
    • Journal Title

      実験医学 増刊

      Volume: 35(12) Pages: 27-35

    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Journal Article] 「プリオン病のアミロイドーシス」最新アミロイドーシスのすべて2017

    • Author(s)
      照屋健太、堂浦克美
    • Journal Title

      医師薬出版

      Volume: - Pages: 226-236

    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Journal Article] Melanin or melanin-like substance interacts with the N-terminal portion of prion protein and inhibits abnormal prion protein formation in prion-infected cells.2017

    • Author(s)
      Taichi Hamanaka, Keiko Nishizawa, Yuji Sakasegawa, Ayumi Oguma, Kenta Teruya, Hiroshi Kurahashi, Hideyuki Hara, Suehiro Sakaguchi, Katsumi Doh-ura
    • Journal Title

      Journal of Virology

      Volume: 印刷中 Issue: 6

    • DOI

      10.1128/jvi.01862-16

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01560, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-26293212, KAKENHI-PROJECT-15K15380, KAKENHI-PROJECT-15K01804
  • [Journal Article] プリオン病の多様性と治療開発2017

    • Author(s)
      逆瀬川 裕二、堂浦 克美
    • Journal Title

      実験医学 増刊

      Volume: 35(12) Pages: 27-35

    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Journal Article] Pyrene conjugation and spectroscopic analysis of hydroxypropyl methylcellulose compounds successfully demonstrated a local dielectric difference associated with in vivo anti-prion activity.2017

    • Author(s)
      Teruya K, Oguma A, Nishizawa K, Kamitakahara H, Doh-ura K.
    • Journal Title

      PLoS One.

      Volume: 12(9) Issue: 9 Pages: e0185357-e0185357

    • DOI

      10.1371/journal.pone.0185357

    • NAID

      120006878530

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-15K01804
  • [Journal Article] A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents.2016

    • Author(s)
      Teruya K, Oguma A, Nishizawa K, Kawata M, Sakasegawa Y, Kamitakahara H, Doh-ura K.
    • Journal Title

      PLoS Pathog.

      Volume: 12(12) Issue: 12 Pages: e1006045-e1006045

    • DOI

      10.1371/journal.ppat.1006045

    • NAID

      120005980891

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-15K01804
  • [Journal Article] Heparinase I-specific disaccharide unit of heparin is a key structure but insufficient for exerting anti-prion activity in prion-infected cells.2015

    • Author(s)
      Teruya K, Wakao M, Sato M, Hamanaka T, Nishizawa K, Funayama Y, Sakasegawa Y, Suda Y, Doh-ura K.
    • Journal Title

      BBRC

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Journal Article] プリオン(異常プリオン蛋白)の伝播2015

    • Author(s)
      倉橋 洋史、堂浦 克美.
    • Journal Title

      Clinical Neuroscience

      Volume: 33(3) Pages: 260-264

    • Data Source
      KAKENHI-PROJECT-24659424
  • [Journal Article] Efficacy and Mechanism of a Glycoside Compound Inhibiting Abnormal Prion Protein Formation in Prion-Infected Cells: Implications of Interferon and Phosphodiesterase 4D-Interacting Protein.2014

    • Author(s)
      Nishizawa K, Oguma A, Kawata M, Sakasegawa Y, Teruya K, Doh-Ura K.
    • Journal Title

      J Virol.

      Volume: 88 Issue: 8 Pages: 4083-4099

    • DOI

      10.1128/jvi.03775-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23550195, KAKENHI-PROJECT-24659424
  • [Journal Article] Detection of Proteinase K-resistant prion protein(PrPres) in mouse neuroblastoma cells.2014

    • Author(s)
      Kurahashi H, Sakasegawa Y, Doh-ura K.
    • Journal Title

      PSSJ Arch

      Volume: 7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Journal Article] Amyloid-binding compounds and their anti-prion potency.2013

    • Author(s)
      Teruya K1, Doh-ura K.
    • Journal Title

      Curr Top Med Chem.

      Volume: 13(19) Pages: 2522-2532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Journal Article] Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion.2012

    • Author(s)
      Honda H, Sasaki K, Minaki H, Masui K, Suzuki SO, Doh-ura K, Iwaki T.
    • Journal Title

      Neuropathology

      Volume: 32 Pages: 124-132

    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion.2012

    • Author(s)
      Honda H, Sasaki K, Minaki H, Masui K, Suzuki SO, Doh-ura K, Iwaki T.
    • Journal Title

      Neuropathology.

      Volume: 32(2) Pages: 124-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Journal Article] Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion2012

    • Author(s)
      Honda H, Sasaki K, Minaki H, Masui K, Suzuki SO, Doh-Ura K, Iwaki T
    • Journal Title

      Neuropathology

      Volume: 32 Issue: 2 Pages: 124-132

    • DOI

      10.1111/j.1440-1789.2011.01245.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300116, KAKENHI-PROJECT-22390172
  • [Journal Article] プリオン病の疫学から治療までプリオン病の分子標的治療薬の開発2011

    • Author(s)
      逆瀬川裕二,木村朋寛,堂浦克美
    • Journal Title

      NEUROINFECTION

      Volume: 16 Pages: 79-86

    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Binding and selectivity of the marine toxins neodysiherbaine A, and its synthetic analogues, to GluK1 and GIuK2 kainate receptors2011

    • Author(s)
      M.Unno, M.Shinohara, K.Takayama, H.Tanaka, K.Teruya, K.Doh-ura, R.Sakai, M.Sasaki, M.Ikeda-Saito
    • Journal Title

      Journal of Molecular Biology

      Volume: 413 Issue: 3 Pages: 667-683

    • DOI

      10.1016/j.jmb.2011.08.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21241050, KAKENHI-PROJECT-21350087, KAKENHI-PROJECT-22390172, KAKENHI-PROJECT-22770096, KAKENHI-PLANNED-23102016, KAKENHI-PUBLICLY-23121504, KAKENHI-PROJECT-23550195
  • [Journal Article] 【認知症学下-その解明と治療の最新知見-】臨床編プリオン病の診断と治療孤発性プリオン病Creutzfeldt-Jakob病と治療薬開発2011

    • Author(s)
      逆瀬川裕二,堂浦克美
    • Journal Title

      日本臨床

      Volume: 69 Pages: 411-414

    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] プリオン病の疫学から治療まで プリオン病の分子標的治療薬の開発.2011

    • Author(s)
      逆瀬川 裕二,木村 朋寛, 堂浦 克美.
    • Journal Title

      NEUROINFECTION

      Volume: 16 Pages: 79-86

    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.2011

    • Author(s)
      Unno M, Shinohara M, Takayama K, Tanaka H, Teruya K, Doh-ura K, Sakai R, Sasaki M, Ikeda-Saito M.
    • Journal Title

      J Mol Biol

      Volume: 413(3) Pages: 667-683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Anti-prion activity of protein-bound polysaccharide K in prion-infected cells and animals2011

    • Author(s)
      Hamanaka T, Sakasegawa Y, Ohmoto A, Kimura T, Ando T, Doh-ura K.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405(2) Issue: 2 Pages: 285-290

    • DOI

      10.1016/j.bbrc.2011.01.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Anti-prion activity of protein-bound polysaccharide K in prion-infected cells and animals2011

    • Author(s)
      Hamanaka T, Sakasegawa Y, Omoto A, Kimura T, Ando T, Doh-ura K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 285-290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] 【認知症学 下-その解明と治療の最新知見-】臨床編 プリオン病の診断と治療 孤発性プリオン病 Creutzfeldt-Jakob病と治療薬開発.2011

    • Author(s)
      逆瀬川 裕二, 堂浦 克美.
    • Journal Title

      日本臨床

      Volume: 69 Pages: 411-414

    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Anti-prion activities and drug-like potential of functionalized quinacrine analogs with basic phenyl residues at the 9-amino position.2011

    • Author(s)
      Nguyen T, Sakasegawa Y, Doh-ura K, Go ML.
    • Journal Title

      Eur J Med Chem

      Volume: 46(7) Pages: 2917-2929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Anti-prion activities and drug-like potential of functionalized quinacrine analogs with basic phenylresidues at the 9-amino position2011

    • Author(s)
      Nguyen T, Sakasegawa Y, Doh-ura K, Go ML.
    • Journal Title

      EurJ Med Chem

      Volume: 46(7) Issue: 7 Pages: 2917-2929

    • DOI

      10.1016/j.ejmech.2011.04.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Semisynthesis of a protein with cholesterol at the C-terminal, targeted to the cell membrane of live cells2010

    • Author(s)
      Teruya K, Nishizawa K, Doh-ura K
    • Journal Title

      Protein J

      Volume: 29 Pages: 493-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] In vivo detection of prion amyloid plaques using [(11)C]BF-227 PET2010

    • Author(s)
      Okamura N, Shiga Y, Furumoto S, Tashiro M, Tsuboi Y, Furukawa K, Yanai K, Iwata R, Arai H, Kudo Y, Itoyama Y, Doh-ura K
    • Journal Title

      Eur J Nucl Med Mol Imaging

      Volume: 37 Pages: 934-941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Semisynthesis of a protein with cholesterol at the C-terminal, targeted to the cell membrane of live cells2010

    • Author(s)
      Teruya K, Nishizawa K, Doh-ura K.
    • Journal Title

      Protein J.

      Volume: 29(7) Issue: 7 Pages: 493-500

    • DOI

      10.1007/s10930-010-9278-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] In vivo detection of prion amyloid plaques using [(11)C]BF-227 PET2010

    • Author(s)
      Okamura N, Shiga Y, Furumoto S, Tashiro M, Tsuboi Y, Furukawa K, Yanai K, Iwata R, Arai H, Kudo Y, Itoyama Y, Doh-ura K.
    • Journal Title

      Eur J Nucl Med Mol Imaging

      Volume: 37 (5) Issue: 5 Pages: 934-941

    • DOI

      10.1007/s00259-009-1314-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] GABAA receptor subunit beta1 is involved in the formation of protease-resistant prion protein in prion-infected neuroblastoma cells2010

    • Author(s)
      Kimura T, Ishikawa K, Sakasegawa Y, Teruya K, Sata T, Schatzl H, Doh-ura K
    • Journal Title

      FEBS Lett

      Volume: 584 Pages: 1193-1198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Journal Article] Amyloidophilic compounds for prion diseases2009

    • Author(s)
      Teruya K, Kawagoe K, Kimura T, Chen CJ, Sakasegawa Y, Doh-ura K
    • Journal Title

      Infect Disord Drug Targets 9(1)

      Pages: 15-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Amyloidophilic compounds for prion diseases2009

    • Author(s)
      Teruya K, Kawagoe K, Kimura T, Chen CJ, Sakasegawa Y, Doh-ura K
    • Journal Title

      Infect Disord Drug Targets. 9(1)

      Pages: 15-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Amyloidophilic compounds for prion diseases2009

    • Author(s)
      Teruya K, Kawagoe K, Kimura T, Chen CJ, Sakasegawa Y, Doh-ura K
    • Journal Title

      Infect Disord Drug Targets 9(1)

      Pages: 15-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Antiprion activity of functionalized 9-aminoacridines related to quinacrine2008

    • Author(s)
      Nguyen TH, Lee CY, Teruya K, Ong WY, Doh-ura K, Go ML
    • Journal Title

      Bioorg Med Chem. 16(14)

      Pages: 6737-6746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Antiprion activity of functionalized 9-aminoacridines related to quinacrine2008

    • Author(s)
      Nguyen TH, Lee CY, Teruya K, Ong WY, Doh-ura K, Go ML
    • Journal Title

      Bioorg Med Chem 16(14)

      Pages: 6737-6746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Antiprion activity of functionalized 9-aminoacridines related to quinacrine2008

    • Author(s)
      Nguyen TH, Lee CY, Teruya K, Ong WY, Doh-ura K, Go ML
    • Journal Title

      Bioorg Med Chem 16(14)

      Pages: 6737-6746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Chelating compound, chrysoidine, is more effective in both antiprion activity and brain endothelial permeability than quinacrine2007

    • Author(s)
      Doh-ura K, Tamura K, Karube Y, Naito M, Tsuruo T, Kataoka Y
    • Journal Title

      Cell.Mol.Neurobiol 27(3)

      Pages: 303-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] プリオン病の診断支援・治療へ試み。2007

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      日本臨床 65(8)

      Pages: 1417-1422

    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] 神経感染症の治療の進歩と将来の展望プリオン病への治療アプローチ。2007

    • Author(s)
      堂浦克美
    • Journal Title

      神経治療学 24(6)

      Pages: 647-650

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice.2007

    • Author(s)
      Hao HP, Doh-Ura K, Nakanishi H
    • Journal Title

      J. Neurosci. Res. 85(10)

      Pages: 2196-2206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Chelating compound, chrysoidine, is more effective in both antiprion activity and brain endothelial permeability than quinacrine.2007

    • Author(s)
      Doh-ura K, Tamura K, Karube Y, Naito M, Tsuruo T, Kataoka Y
    • Journal Title

      Cell. Mo1. Neurobiol. 27(3)

      Pages: 303-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Chelating compound, chrysoidine, is more effective in both anti-prion activity and brain endothelial permeability than quinacrine.2007

    • Author(s)
      Doh-ura K, Tamura K, Karube Y, Naito M, Tsuruo T, Kataoka Y
    • Journal Title

      Cell. Mol. Neurobiol. (in press)

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Chelating compound, chrysoidine, is more effective in both a ntiprion activity and brain endothelial permeability than quinacrine.2007

    • Author(s)
      Doh-ura K, Tamura K, Karube Y, Naito M, Tsuruo T, Kataoka Y
    • Journal Title

      Cell. Mol. Neurobiol. 27(3)

      Pages: 303-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate?2007

    • Author(s)
      Rainov NG, Tsuboi Y, Krolak-Salmon P, Vighetto A, Doh-Ura K
    • Journal Title

      Expert Opin. Biol. Ther. 7

      Pages: 713-726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] プリオン病の分子標的治療2007

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      神経研究の進歩 59(4)

      Pages: 405-414

    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice2007

    • Author(s)
      Hao HP, Doh-Ura K, Nakanishi H
    • Journal Title

      J.Neurosci.Res 85(10)

      Pages: 2196-2206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] プリオン病の分子標的治療。2007

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      神経研究の進歩 59(4)

      Pages: 405-414

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Two different clinical phenotypes of Creutzfeldt-Jakob disease with a M232R substitution.2007

    • Author(s)
      Shiga Y, Satoh K, Kitamoto T, Kanno S, Nakashima I, Sato S, Fujihara K, Takata H, Nobukuni K, Kuroda S, Takano H, Umeda Y, Konno H, Nagasato K, Satoh A, Matsuda Y, Hidaka M, Takahashi H, Sano Y, Kim K, Konishi T, Doh-Ura K, Sato T, Sasaki K, Nakamura Y, Yamada M, Mizusawa H,Itoyama Y
    • Journal Title

      J. Neurol. 254

      Pages: 1509-1517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice.2007

    • Author(s)
      Hao HP, Doh-Ura K, Nakanishi H
    • Journal Title

      J. Neurosci. Res. 85(10)

      Pages: 2196-2206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Prophylactic effect of dietary seaweed Fucoidan against enteral prion infection2007

    • Author(s)
      Doh-Ura K, Kuge T, Uomoto M, Nishizawa K, Kawasaki Y, Iha M
    • Journal Title

      Antimicrob. Agents Chemother 51(6)

      Pages: 2274-2277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] プリオン病の診断支援・治療へ試み。2007

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      日本臨床 65(8)

      Pages: 1417-1422

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate?2007

    • Author(s)
      Rainov NG, Tsuboi Y, Krolak-Salmon P, Vighetto A, Doh-Ura K
    • Journal Title

      Expert Opin. Biol. Ther. 7

      Pages: 713-726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Two different clinical phenotypes of Creutzfeldt-Jakob disease with a M232R substitution2007

    • Author(s)
      Shiga Y, Satoh K, Kitamoto T, Kanno S, Nakashima I, Sato S, Fujihara K, Takata H, Nobukuni K, Kuroda S, Takano H, Umeda Y, Konno H, Nagasato K, Satoh A, Matsuda Y, Hidaka M, Takahashi H, Sano Y, Kim K, Konishi T, Doh-Ura K, Sato T, Sasaki K, Nakamura Y, Yamada M, Mizusawa H, Itoyama Y
    • Journal Title

      J.Neurol 254

      Pages: 1509-1517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Two different clinical phenotypes of Creutzfeldt-Jakob disease with a M232R substitution.2007

    • Author(s)
      Shiga Y, Satoh K, Kitamoto T, Kanno S, Nakashima I, Sato S, Fujihara K, Takata H, Nobukuni K, Kuroda S, Takano H, Umeda Y, Konno H, Nagasato K, Satoh A, Matsuda Y Hidaka M, Takahashi H, Sano Y, Kim K, Konishi T, Doh-Ura K, Sato T, Sasaki K, Nakamura Y, Yamada M, Mizusawa H, Itoyama Ymada M, Mizusawa H, Itoyama Y
    • Journal Title

      J. Neurol. 254

      Pages: 1509-1517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner.2007

    • Author(s)
      Kawasaki Y, Kawagoe K, Chen CJ, Teruya K, Sakasegawa Y, Doh-Ura K
    • Journal Title

      J. Virol. 81(23)

      Pages: 12889-12898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate2007

    • Author(s)
      Rainov NG, Tsuboi Y, Krolak-Salmon P, Vighetto A, Doh-Ura K
    • Journal Title

      Expert Opin. Biol. 7

      Pages: 713-726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] 神経感染症の治療の進歩と将来の展望プリオン病への治療アプローチ2007

    • Author(s)
      堂浦克美
    • Journal Title

      神経治療学 24(6)

      Pages: 647-650

    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] プリオン病の診断支援・治療への試み2007

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      日本臨床 65(8)

      Pages: 1417-1422

    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] プリオン病の分子標的治療。2007

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      神経研究の進歩 59(4)

      Pages: 405-414

    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Prophylactic effect of dietary seaweed Fucoidan against enteral prion infection.2007

    • Author(s)
      Doh-Ura K, Kuge T, Uomoto M, Nishizawa K, Kawasaki Y, Iha M
    • Journal Title

      Antimicrob. Agents Chemother. 51(6)

      Pages: 2274-2277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] 神経感染症の治療の進歩と将来の展望 プリオン病への治療アプローチ。2007

    • Author(s)
      堂浦克美
    • Journal Title

      神経治療学 24(6)

      Pages: 647-650

    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner.2007

    • Author(s)
      Kawasaki Y, Kawagoe K, Chen CJ, Teruya K, Sakasegawa Y, Doh-Ura K
    • Journal Title

      J. Virol. 81(23)

      Pages: 12889-12898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner2007

    • Author(s)
      Kawasaki Y, Kawagoe K, Chen CJ, Teruya K, Sakasegawa Y, Doh-Ura K
    • Journal Title

      J. Virol 81(23)

      Pages: 12889-12898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Journal Article] Prophylactic effect of dietary seaweed Fucoidan against enteral prion infection.2007

    • Author(s)
      Doh-Ura K, Kuge T, Uomoto M, Nishizawa K, Kawasaki Y, Iha M
    • Journal Title

      Antimicrob. Agents Chemother. 51(6)

      Pages: 2274-2277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Surface plasmon resonance analysis for the screening of anti-prion compounds.2006

    • Author(s)
      Kawatake S, Nishimura Y, Sakaguchi S, Iwaki T, Doh-ura K
    • Journal Title

      Biol. Pharm. Bull. 29(5)

      Pages: 927-932

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Styrylbenzoazole derivatives for imaging of prion plaques and treatment of transmissible spongiform encephalopathies.2006

    • Author(s)
      Ishikawa K, Kudo Y, Nishida N, Suemoto T, Sawada T, Iwaki T, Doh-ura K
    • Journal Title

      J. Neurochem. 99

      Pages: 198-205

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Brain stem lesions in sporadic Creutzfeldt Jakob disease : A histopathological and immunohistochemical study.2006

    • Author(s)
      Shintaku M, Yutani C, Doh-ura K
    • Journal Title

      Neuropathol. 26

      Pages: 43-49

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] プリオン病の治療-その現状と展望-.2006

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      Brain Medical 18(4)

      Pages: 356-370

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Increased asymmertric pulvinar magnetic resonance imaging signals in Creutzfeldt-Jakob disease with florid plaques following a cadaveric dura mater graft.2006

    • Author(s)
      Wakisaka Y, Santa N, Doh-ura K, Kitamoto T, Ibayashi S, Iida M, Iwaki T
    • Journal Title

      Neuropathol. 26

      Pages: 82-88

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Clusterin expression in follicular dendritic cells associated with prion protein accumulation.2006

    • Author(s)
      Sasaki K, Doh-ura K, Ironside J, Mabbott N, Iwaki T
    • Journal Title

      J. Pathol. 209(4)

      Pages: 484-491

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] 孤発性クロイツフェルトーヤコブ病と6種類のサブタイプ.2006

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Journal Title

      Medical Briefs in Brain & Nerve 15(4)

      Pages: 5-6

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] プリオンイメージングの試み.2006

    • Author(s)
      石川謙介, 堂浦克美
    • Journal Title

      Clinical Neuroscience 24(3)

      Pages: 313-316

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Metal complexes with superoxide dismutase-like activity as candidates for anti-prion drug.2006

    • Author(s)
      Fukuuchi T, Doh-ura K, Yoshihara S, Ohta S
    • Journal Title

      Bioorg. Med. Chem. Lett. 16

      Pages: 5982-5987

    • Data Source
      KAKENHI-PROJECT-18659253
  • [Journal Article] Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models2004

    • Author(s)
      Doh-ura K
    • Journal Title

      J Virol 78

      Pages: 4999-5006

    • Data Source
      KAKENHI-PROJECT-16639011
  • [Journal Article] Prion diseases : disease diversity and therapeutics2004

    • Author(s)
      Doh-ura K
    • Journal Title

      Rinsho Shinkeigaku 44

      Pages: 855-856

    • NAID

      10014114745

    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] プリオン病:遺伝子異常と臨床像・病理像及び治療薬開発の展望2004

    • Author(s)
      堂浦克美
    • Journal Title

      臨床神経学 44

      Pages: 855-856

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Prion diseases : disease diversity and therapeutics.2004

    • Author(s)
      Doh-ura K.
    • Journal Title

      Rinsho Shinkeigaku. (Jpn) 44

      Pages: 855-856

    • NAID

      10014114745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models2004

    • Author(s)
      Doh-ura K
    • Journal Title

      J Virol 78

      Pages: 4999-5006

    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Prion diseases : disease diversity and therapeutics2004

    • Author(s)
      Doh-ura K
    • Journal Title

      Rinsho Shinkeigaku 44

      Pages: 855-856

    • NAID

      10014114745

    • Data Source
      KAKENHI-PROJECT-16639011
  • [Journal Article] Treatment of transmissible spongiform encephalonathy by intraventricular drug infusion.2004

    • Author(s)
      Doh-ura K, et al.
    • Journal Title

      Journal of Virology 78

      Pages: 4999-5006

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion.2004

    • Author(s)
      Doh-ura K, et al.
    • Journal Title

      Journal of Virology 78

      Pages: 4999-5006

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Prion diseases, clinical and pathological features.2003

    • Author(s)
      Doh-ura K.
    • Journal Title

      Byori-to-rinsho (Jpn) 21

      Pages: 230-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] プリオン病治療薬の開発2003

    • Author(s)
      堂浦克美
    • Journal Title

      神経研究の進歩 47

      Pages: 109-118

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Development of anti-prion disease drugs.2003

    • Author(s)
      Doh-ura K.
    • Journal Title

      Shinkeikenkyu-no-shinpo (Jpn) 47

      Pages: 109-118

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Therapeutics for prion diseases.2003

    • Author(s)
      Doh-ura K.
    • Journal Title

      Rinsho Shinkeigaku. (Jpn) 43

      Pages: 820-822

    • NAID

      10013677873

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] プリオン病.新興・再興感染症、輸入感染症の臨床と病理2003

    • Author(s)
      堂浦克美
    • Journal Title

      病理と臨床 21

      Pages: 230-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] プリオン病の治療2003

    • Author(s)
      堂浦克美
    • Journal Title

      臨床神経学 43

      Pages: 820-822

    • NAID

      10013677873

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Development of anti-prion disease drugs.2002

    • Author(s)
      Doh-ura K.
    • Journal Title

      Igaku-no-ayumi (Jpn) 203(10)

      Pages: 923-930

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] プリオン病の治療薬開発2002

    • Author(s)
      堂浦克美
    • Journal Title

      医学のあゆみ 203(10)

      Pages: 923-930

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] ヒトのプリオン病とその治療薬剤開発の現状2002

    • Author(s)
      堂浦克美
    • Journal Title

      ファルマシア 38

      Pages: 635-639

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Journal Article] Human prion diseases and therapeutic drug development.2002

    • Author(s)
      Doh-ura K.
    • Journal Title

      Pharmacia (Jpn) 38

      Pages: 635-639

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] コンフォメーション病の予防又は治療剤、及びコンフォメーション病医薬のスクリーニング方法2018

    • Inventor(s)
      照屋 健太、西澤 桂子、堂浦 克美
    • Industrial Property Rights Holder
      照屋 健太、西澤 桂子、堂浦 克美
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Patent] コンフォメーション病の予防又は治療剤、及びコンフォメーション病医薬のスクリーニング方法2018

    • Inventor(s)
      照屋 健太、西澤 桂子、堂浦 克美、
    • Industrial Property Rights Holder
      照屋 健太、西澤 桂子、堂浦 克美、
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Patent] コンフォメーション病治療用材料、及びその製造方法、並びにコンフォメーション病医薬のスクリーニング方法2017

    • Inventor(s)
      堂浦 克美、照屋 健太
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-169312
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Patent] コンフォメーション病治療用材料、及びその製造方法、並びにコンフォメーション病医薬のスクリーニング方法2017

    • Inventor(s)
      堂浦 克美、照屋 健太
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-169312
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Patent] コンフォメーション病医薬組成物及びその製造方法2016

    • Inventor(s)
      堂浦 克美、照屋 健太、西澤 桂子、小熊 歩
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-05-09
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Patent] コンフォメーション病医薬組成物2012

    • Inventor(s)
      堂浦 克美
    • Industrial Property Rights Holder
      東北大学、伊藤ハム株式会社
    • Industrial Property Number
      2008-512153
    • Acquisition Date
      2012-04-27
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Patent] 異常型プリオン蛋白質の濃縮方法、 および除去方法2011

    • Inventor(s)
      堂浦 克美 、照屋 健太、竹中 繁織、大塚 圭一
    • Industrial Property Rights Holder
      東北大学、九州工業大学
    • Industrial Property Number
      2006-071881
    • Acquisition Date
      2011-07-01
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Patent] プリオン病の予防及び/又は治療用薬、並びに異常プリオン蛋白質の発現抑制方法2009

    • Inventor(s)
      堂浦克美、木村朋寛
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Number
      2009-059468
    • Filing Date
      2009-03-12
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] プリオン病の予防及び/又は治療用薬、並びに異常プリオン蛋白質の発現抑制方法2009

    • Inventor(s)
      堂浦克美、木村朋寛
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2009-03-12
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] プリオン病の予防及び/又は治療用薬、並びに異常プリオン蛋白質の発現抑制方法2009

    • Inventor(s)
      堂浦克美, 木村朋寛
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Number
      2009-059468
    • Filing Date
      2009-03-12
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-11-04
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-10-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-10-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-11-04
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-11-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-10-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-10-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] コンフォメーション病医薬組成物2008

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学伊藤ハム
    • Filing Date
      2008-11-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] 抗プリオン活性剤及び異常型プリオン蛋白質生成の阻害方法。2007

    • Inventor(s)
      宮田直樹、鈴木孝禎、中川秀彦、太田茂、堂浦克美、福内友子
    • Industrial Property Rights Holder
      名古屋市立大学
    • Filing Date
      2007-10-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] 抗プリオン活性剤及び異常型プリオン蛋白質生成の阻害方法。2007

    • Inventor(s)
      宮田直樹、鈴木孝禎、中川秀彦、太田茂、堂浦克美、福内友子
    • Industrial Property Rights Holder
      名古屋市立大学
    • Filing Date
      2007-10-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] コンフォメーション病医薬組成物2007

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学, 伊藤ハム株式会社
    • Filing Date
      2007-04-20
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] プリオン病治療薬及びそのスクリーニング方法。2007

    • Inventor(s)
      堂浦克美、照屋健太、隅田泰生
    • Industrial Property Rights Holder
      東北大学、鹿児島大学
    • Industrial Property Number
      2007-102005
    • Filing Date
      2007-04-09
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] コンフォメーション病医薬組成物。2007

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学、伊藤ハム株式会社
    • Filing Date
      2007-04-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] プリオン病治療薬及びそのスクリーニング方法。2007

    • Inventor(s)
      堂浦克美、照屋健太、隅田泰生
    • Industrial Property Rights Holder
      東北大学、鹿児島大学
    • Industrial Property Number
      2007-102005
    • Filing Date
      2007-04-09
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] 抗プリオン活性剤及び異常型プリオン蛋白質生成の阻害方法2007

    • Inventor(s)
      宮田直樹, 鈴木孝禎, 中川秀彦, 太田茂, 堂浦克美, 福内友子
    • Industrial Property Rights Holder
      名古屋市立大学
    • Filing Date
      2007-10-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] コンフォメーション病医薬組成物。2007

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学、伊藤ハム株式会社
    • Filing Date
      2007-04-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] プリオン治療薬及びそのスクリーニング方法2007

    • Inventor(s)
      堂浦克美, 照屋健太, 隅田泰生
    • Industrial Property Rights Holder
      東北大学, 鹿児島大学
    • Industrial Property Number
      2007-102005
    • Filing Date
      2007-04-09
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Patent] 電気化学的抗原検出法とそのための装置並びに検出チップ2006

    • Inventor(s)
      竹中繁織, 大塚圭一, 堂浦克美, 照屋健太
    • Industrial Property Rights Holder
      九州工業大学, 東北大学
    • Industrial Property Number
      2006-065744
    • Filing Date
      2006-03-10
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] 異常型プリオン蛋白質濃縮方法、および除去方法2006

    • Inventor(s)
      堂浦克美, 照屋健太, 竹中繁織, 大塚圭一
    • Industrial Property Rights Holder
      東北大学, 九州工業大学
    • Industrial Property Number
      2006-071881
    • Filing Date
      2006-03-15
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] コンフォメーション病医薬組成物2006

    • Inventor(s)
      堂浦克美
    • Industrial Property Rights Holder
      東北大学, (株)伊藤ハム
    • Industrial Property Number
      2006-117294
    • Filing Date
      2006-04-20
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Patent] プリオン病発症予防剤とそれを含む食品添加剤及び飼料添加剤2005

    • Inventor(s)
      堂浦 克美
    • Industrial Property Rights Holder
      堂浦 克美, 伊藤ハム
    • Industrial Property Number
      2005-051999
    • Filing Date
      2005-02-25
    • Data Source
      KAKENHI-PROJECT-16639011
  • [Patent] プリオン病発症予防剤とそれを含む食品添加剤及び飼料添加剤2005

    • Inventor(s)
      堂浦 克美
    • Industrial Property Rights Holder
      堂浦 克美, 伊藤ハム
    • Industrial Property Number
      2005-051999
    • Filing Date
      2005-02-25
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] 体外診断キット及び体外診断方法2004

    • Inventor(s)
      横田 博, 堂浦 克美
    • Industrial Property Rights Holder
      堂浦 克美, 伊藤ハム, 酪農学園
    • Industrial Property Number
      2004-216510
    • Filing Date
      2004-07-23
    • Data Source
      KAKENHI-PROJECT-16639011
  • [Patent] 体外診断キット及び体外診断方法2004

    • Inventor(s)
      横田 博, 堂浦克美
    • Industrial Property Rights Holder
      横田 博, 堂浦克美, 伊藤ハム(株)
    • Patent Publication Number
      2006-038536
    • Filing Date
      2004-07-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16613010
  • [Patent] 体外診断キット及び体外診断方法2004

    • Inventor(s)
      横田 博, 堂浦 克美
    • Industrial Property Rights Holder
      堂浦 克美, 伊藤ハム, 酪農学園
    • Industrial Property Number
      2004-216510
    • Filing Date
      2004-07-23
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] 異常プリオンの電気化学的検出方法2004

    • Inventor(s)
      竹中 繁織, 野島 高彦, 大塚 圭一, 堂浦 克美
    • Industrial Property Rights Holder
      九州大学, 東北大学
    • Industrial Property Number
      2004-287562
    • Filing Date
      2004-09-30
    • Data Source
      KAKENHI-PROJECT-16639011
  • [Patent] 異常プリオンの電気化学的検出方法2004

    • Inventor(s)
      竹中 繁織, 野島 高彦, 大塚 圭一, 堂浦 克美
    • Industrial Property Rights Holder
      九州大学,東北大学
    • Industrial Property Number
      2004-287562
    • Filing Date
      2004-09-30
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] プリオン蛋白蓄積性疾患の診断プローブおよび治療薬ならびにプリオン蛋白の染色剤2003

    • Inventor(s)
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Rights Holder
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Filing Date
      2003
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] プリオン蛋白蓄積性疾患の診断プローブおよび治療薬2003

    • Inventor(s)
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Rights Holder
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Number
      2003-073344
    • Filing Date
      2003
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] プリオン蛋白蓄積性疾患の診断プローブ及び治療薬としてのベンゾチアゾール環含有化合物2002

    • Inventor(s)
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Rights Holder
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Number
      2002-255015
    • Filing Date
      2002
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] プリオン蛋白蓄積性疾患の診断プローブ及び治療薬としてのベンゾオキサゾール環含有化合物2002

    • Inventor(s)
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Rights Holder
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Number
      2002-255014
    • Filing Date
      2002
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] プリオン蛋白蓄積性疾患の診断プローブ及び治療薬としてのベンゾイミダゾール環含有化合物2002

    • Inventor(s)
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Rights Holder
      工藤 幸司, 澤田 徹, 堂浦 克美
    • Industrial Property Number
      2002-255013
    • Filing Date
      2002
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Patent] 病原性プリオンタンパク質生成阻害剤およびその使用方法2002

    • Inventor(s)
      堂浦 克美, 久保 郁子
    • Industrial Property Rights Holder
      堂浦 克美, 久保 郁子
    • Industrial Property Number
      2002-265321
    • Filing Date
      2002
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207030
  • [Presentation] Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on Acquired and Spontaneous Prion Diseases in Humanized Transgenic Mice2023

    • Author(s)
      Wang Z, Binyamin O, Martinez MC, Gilliland T, Teruya K, Gerasimenko M, Doh-ura K, Gabizon R, Kong Q, Zou WQ
    • Organizer
      Asia Pacific Prion Symposium 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] プリオンの概要2023

    • Author(s)
      堂浦克美
    • Organizer
      第 128 回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on Acquired and Spontaneous Prion Diseases in Humanized Transgenic Mice2023

    • Author(s)
      Wang Z, Binyamin O, Martinez MC, Gilliland T, Teruya K, Gerasimenko M, Doh-ura K, Gabizon R, Kong Q, Zou WQ
    • Organizer
      PRION 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] Candidate drugs for treatment of prion diseases.2023

    • Author(s)
      Teruya K, Doh-ura K
    • Organizer
      Asia Pacific Prion Symposium 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] プリオンの概要2023

    • Author(s)
      堂浦克美
    • Organizer
      第 128 回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Presentation] Characterization of the actions of CRANAD on two prion strains and PrP-amyloid2022

    • Author(s)
      Teruya K, Iwabuchi S, Okada M, Yaguchi N, Konno H, Doh-ura K
    • Organizer
      第59 回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] Structure-Activity relationship of curcumin-related compounds in ScN2a and N1672022

    • Author(s)
      Teruya K, Iwabuchi S, Kato R, Konno H, Doh-ura K
    • Organizer
      Asian Pacific Prion Symposium 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] Characterization of the actions of CRANAD on two prion strains and PrP-amyloid2022

    • Author(s)
      Teruya K, Iwabuchi S, Okada M, Yaguchi N, Konno H, Doh-ura K
    • Organizer
      第59 回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Presentation] Our Quest for Anti-prion Compounds 20222022

    • Author(s)
      Teruya K, Doh-ura K
    • Organizer
      Asian Pacific Prion Symposium 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24239
  • [Presentation] Structure-Activity relationship of curcumin-related compounds in ScN2a and N1672022

    • Author(s)
      Teruya K, Iwabuchi S, Kato R, Konno H, Doh-ura K
    • Organizer
      Asian Pacific Prion Symposium 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Presentation] Our Quest for Anti-prion Compounds 20222022

    • Author(s)
      Teruya K, Doh-ura K
    • Organizer
      Asian Pacific Prion Symposium 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Presentation] フェロトーシス阻害剤による異常型プリオンタンパク質蓄積抑制機構の解明.2021

    • Author(s)
      松井 美紀、照屋 健太、小熊 歩、村山 和隆、堂浦 克美.
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Presentation] Photoreaction-induced SDS-resistant PrPSc/res oligomer formation.2021

    • Author(s)
      Kenta Teruya, Toshiya Ishikawa, Sara Iwabuchi, Miki Watanabe-Matsui, Katsumi Doh-ura.
    • Organizer
      第58回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] フェロトーシス阻害剤による異常型プリオンタンパク質蓄積抑制機構の解明.2021

    • Author(s)
      松井 美紀、照屋 健太、小熊 歩、村山 和隆、堂浦 克美.
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Photoreaction-induced SDS-resistant PrPSc/res oligomer formation.2021

    • Author(s)
      Kenta Teruya, Toshiya Ishikawa, Sara Iwabuchi, Miki Watanabe-Matsui, Katsumi Doh-ura.
    • Organizer
      第58回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-21K19435
  • [Presentation] Prophylactic anti-prion effects of cellulose ether compounds depend on host mouse strains.2020

    • Author(s)
      Kenta Teruya, Keiko Nishizawa, Ayumi Oguma, Katsumi Doh-ura.
    • Organizer
      第57回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Characterization of the effects of curcumin related compounds on two prion strains.2020

    • Author(s)
      Sara Iwabuchi, Kenta Teruya, Miki Matsui, Hiroyuki Konno, Katsumi Doh-ura.
    • Organizer
      第57回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Characterization of cellulose ether liposomes for the inhibition of prion formation in prion-infected cells.2019

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Kamitakahara H, Schatzl HM, Gilch S, Doh-ura K.
    • Organizer
      PRION2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Cellulose ether liposomes for the inhibition of prion formation.2019

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Kamitakahara H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Characterization of cellulose ether liposomes for the inhibition of prion formation in prion-infected cells.2019

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Kamitakahara H, Schatzl H, Gilch S, Doh-ura K.
    • Organizer
      PRION2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Protection to prion infection by cellulose ether compounds depends on host mouse strains.2019

    • Author(s)
      Teruya K, Nishizawa K, Oguma A, Sakasegawa Y, Kamitakahara H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Cellulose ethers interfere with CWD prion propagation in vitro and in vivo.2019

    • Author(s)
      Gopalakrishnan P, Yu J, Hannaoui S, Chang SC, Arifin MI, Doh-ura K, Schatzl HM, Gilch S.
    • Organizer
      PRION2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Cellulose ethers interfere with CWD prion propagation in vitro and in vivo.2019

    • Author(s)
      Gopalakrishnan P, Yu J, Hannaoui S, Chang SC, Arifin MI, Doh-ura K, Schatzl HM, Gilch S.
    • Organizer
      PRION2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Protection to prion infection by cellulose ether compounds depends on host mouse strains.2019

    • Author(s)
      Teruya K, Nishizawa K, Oguma A, Sakasegawa Y, Kamitakahara H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Cellulose ether liposomes for the inhibition of prion formation.2019

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Kamitakahara H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03570
  • [Presentation] Liposomal formulation improved the anti-prion activity of cellulose ether compounds in ScN2a cells.2018

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Liposomal formulation improved the anti-prion activity of cellulose ether compounds in ScN2a cells.2018

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] A platinum compound enhances the endogenous proteolytic degradation of the PrPC and PrPres in mouse neuroblastoma N2a cells.2018

    • Author(s)
      Sakasegawa Y, Nishizawa K, Oguma A, Teruya K, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Photoreaction-induced SDS-resistant PrP Sc/res oligomer formation.2018

    • Author(s)
      Teruya K, Nishizawa K, Oguma A, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] A platinum compound enhances the endogenous proteolytic degradation of the PrPC and PrPres in mouse neuroblastoma N2a cells.2018

    • Author(s)
      Sakasegawa Y, Nishizawa K, Oguma A, Teruya K, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Photoreaction-induced SDS-resistant PrP Sc/res oligomer formation.2018

    • Author(s)
      Teruya K, Nishizawa K, Oguma A, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] C-terminal chaperone domain of heat shock protein 90 modifies the conformation of cellular prion protein central region in the presence of copper ion.2017

    • Author(s)
      Sakasegawa Y, Nishizawa K, Oguma A, Teruya K, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Cellulose ether compounds exert protection to prion infection; a biological parameter related to the effectiveness of compounds.2017

    • Author(s)
      Doh-ura K, Teruya K, Nishizawa K, Oguma A, Sakasegawa Y, Kamitakahara H.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Protein Aggregation - Prions: still untouchable agents -.2017

    • Author(s)
      Doh-ura K.
    • Organizer
      XXIII World Congress of Neurology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Anti-prion activities of cellulose ether compounds in prion-infected cells are consistent with long-lasting anti-prion activities in vivo.2017

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Pyrene index of hydroxypropyl methylcellulose compounds correlates with the in vivo long-lasting anti-prion activity.2017

    • Author(s)
      Teruya K, Oguma A, Nishizawa K, Kamitakahara H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Protein Aggregation - Prions: still untouchable agents -.2017

    • Author(s)
      Doh-ura K.
    • Organizer
      XXIII World Congress of Neurology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] C-terminal chaperone domain of heat shock protein 90 modifies the conformation of cellular prion protein central region in the presence of copper ion.2017

    • Author(s)
      Sakasegawa Y, Nishizawa K, Oguma A, Teruya K, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Pyrene index of hydroxypropyl methylcellulose compounds correlates with the in vivo long-lasting anti-prion activity.2017

    • Author(s)
      Teruya K, Oguma A, Nishizawa K, Kamitakahara H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Anti-prion activities of cellulose ether compounds in prion-infected cells are consistent with long-lasting anti-prion activities in vivo.2017

    • Author(s)
      Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19540
  • [Presentation] Cellulose ether compounds exert protection to prion infection; a biological parameter related to the effectiveness of compounds.2017

    • Author(s)
      Doh-ura K, Teruya K, Nishizawa K, Oguma A, Sakasegawa Y, Kamitakahara H.
    • Organizer
      Asian Pacific Prion Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Lessons from recent outcomes of clinical trials and therapeutic studies.2016

    • Author(s)
      Doh-ura K.
    • Organizer
      PRION2016TOKYO
    • Place of Presentation
      東京、一ツ橋ホール
    • Year and Date
      2016-05-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] A platinum compound targeting the cysteine residues of disease-related form of prion protein in cell lysates.2016

    • Author(s)
      Sakasegawa Y, Doh-ura K.
    • Organizer
      PRION2016TOKYO
    • Place of Presentation
      東京、一ツ橋ホール
    • Year and Date
      2016-05-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Effects of cell growth suppression treatments on PrPSc accumulation in prion-infected cells; Paradoxical phenomena observed in butyric acid treatment.2016

    • Author(s)
      Hiyoshi T, Doh-ura K.
    • Organizer
      PRION2016TOKYO
    • Place of Presentation
      東京、一ツ橋ホール
    • Year and Date
      2016-05-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] プリオン病の原因であるPrPScは排除が困難2016

    • Author(s)
      堂浦 克美
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台、仙台国際センター
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] Dimer-sized PrPSc formation detected by western blotting.2016

    • Author(s)
      Teruya K, Doh-ura K.
    • Organizer
      PRION2016TOKYO
    • Place of Presentation
      東京、一ツ橋ホール
    • Year and Date
      2016-05-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05317
  • [Presentation] 抗プリオン化合物の作用機序に関する考察2015

    • Author(s)
      堂浦 克美.
    • Organizer
      徳島大学疾患酵素学研究センタープリオンセミナー
    • Place of Presentation
      徳島大学疾患酵素学研究センター(徳島)
    • Year and Date
      2015-02-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] TSEプリオンとプリオノイドの違い2014

    • Author(s)
      堂浦 克美.
    • Organizer
      第55回日本神経病理学会総会学術研究会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2014-06-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Glycerol enhances the PrPres production via a PI3K signaling pathway in prion-infected neuroblastoma cells.2013

    • Author(s)
      Sakai E, Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2013
    • Place of Presentation
      Nagasaki
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Drug discovery for prion diseases: dream and reality.2013

    • Author(s)
      Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2013
    • Place of Presentation
      Nagasaki
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] プリオン複製に関わる宿主因子の細胞生物学的および生化学的な探索アプローチ。2013

    • Author(s)
      逆瀬川裕二、西澤桂子、堂浦克美.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] ヤコブ病治療研究の現状と課題2012

    • Author(s)
      堂浦克美
    • Organizer
      第6回食と医療の安全に関わるプリオン病の市民講座
    • Place of Presentation
      東京
    • Year and Date
      2012-12-02
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Glycerol enhances the protease-resistance prion protein production in prion-infected neuroblastoma cells.2012

    • Author(s)
      Sakai E, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Melanin-like substances extracted from insect cuticle reduce the PrPres levels in prion-infected cells.2012

    • Author(s)
      Hamanaka T, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Applicational research from yeast prion to mammalian prion with Gpg1 and Rnq1Δ100 that inhibitpropagation of yeast prion.2012

    • Author(s)
      Kurahashi H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Dominant negative inhibition by GPI anchor-less recombinant prion proteins is observed in persistently prion infected N2a cells in a culture medium-dependent manner2012

    • Author(s)
      Sakasegawa Y, Goto Y, Hachiya N, Kaneko K, Doh-ura K.
    • Organizer
      Prion2012
    • Place of Presentation
      Amsterdam (Netherlands)
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Dominant negative inhibition by GPI anchor-less recombinant prion proteins is observed in persistently prion infected N2a cells in a culture medium-dependent manner.2012

    • Author(s)
      Sakasegawa Y, Goto Y, Hachiya N, Kaneko K, Doh-ura K.
    • Organizer
      Prion2012
    • Place of Presentation
      Amsterdam (Netherlands)
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Applicational research from yeast prion to mammalian prion with Gpg1 and Rnq1Δ100 that inhibitpropagation of yeast prion.2012

    • Author(s)
      Kurahashi H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Extracellular heat shock protein 90 enhances PrPres production in prion-infected neuroblastoma N2a cells.2012

    • Author(s)
      Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Melanin-like substances extracted from insect cuticle reduce the PrPres levels in prion-infected cells2012

    • Author(s)
      Hamanaka T, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] K. Extracellular heat shock protein 90 enhances PrPresproduction in prion-infected neuroblastoma N2a cells2012

    • Author(s)
      Sakasegawa Y, Doh-ura
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Glycerol enhances the protease-resistance prion protein production in prion-infected neuroblastoma cells.2012

    • Author(s)
      Sakai E, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] プリオン病に対する治療法の開発.2012

    • Author(s)
      坪井 義夫、堂浦 克美.
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Extracellular heat shock protein 90 enhances PrPres production in prion-infected neuroblastoma N2a cells.2012

    • Author(s)
      Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Glycerol enhances the protease-resistance prion protein production in prion-infected neuroblastoma cells2012

    • Author(s)
      Sakai E, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] ヤコブ病治療研究の現状と課題2012

    • Author(s)
      堂浦 克美.
    • Organizer
      第6回 食と医療の安全に関わるプリオン病の市民講座
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] プリオン病に対する治療法の開発2012

    • Author(s)
      坪井義夫、堂浦克美
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Dominant negative inhibition by GPI anchor-less recombinant prion proteins is observed in persistently prion infected N2a cells in a culture medium-dependent manner.2012

    • Author(s)
      Sakasegawa Y, Goto Y, Hachiya N, Kaneko K, Doh-ura K.
    • Organizer
      Prion2012
    • Place of Presentation
      Amsterdam ( Netherlands )
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] ヤコブ病治療研究の現状と課題.2012

    • Author(s)
      堂浦 克美.
    • Organizer
      第6回 食と医療の安全に関わるプリオン病の市民講座
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Applicational research from yeast prion to mammalian prion with Gpg1 and Rnq1Δ100 that inhibitpropagation of yeast prion2012

    • Author(s)
      Kurahashi H, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Melanin-like substances extracted from insect cuticle reduce the PrPres levels in prion-infected cells.2012

    • Author(s)
      Hamanaka T, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2012
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24659424
  • [Presentation] Structure-activity analysis of anti-prion isoprenoid compounds.2011

    • Author(s)
      Hamanaka T, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2011
    • Place of Presentation
      Karuizawa
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Acidic CC Chemokines are Upregulated in RML-Prion-Infected Neuroblastoma N2a Cells.2011

    • Author(s)
      Sakasegawa Y, Nishizawa K, Oguma A, Doh-ura K.
    • Organizer
      Prion2011
    • Place of Presentation
      Montreal (Canada)
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Anti-prion activity of protein-bound polysaccharide K in prion-infected cells and animals2011

    • Author(s)
      Hamanaka T, Sakasegawa Y, Kimura T, Doh-ura K, Ando T, Ohmoto A
    • Organizer
      Prion 2011
    • Place of Presentation
      Montreal(Canada)
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Secretin receptor is involved in the abnormal PrP levels in prion-infected cells.2011

    • Author(s)
      Kimura T, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2011
    • Place of Presentation
      Karuizawa
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Acidic CC Chemokines are Upregulated in RML-Prion-Infected Neuroblastoma N2a Cells2011

    • Author(s)
      Sakasegawa Y, Nishizawa K, Oguma A, Doh-ura K.
    • Organizer
      Prion2011
    • Place of Presentation
      Montreal(Canada)
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Secretin receptor is involved in the abnormal PrP levels in prion-infected cells2011

    • Author(s)
      Kimura T, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2011
    • Place of Presentation
      Karuizawa
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] ヤコブ病克服の基礎研究2011

    • Author(s)
      堂浦克美
    • Organizer
      第5回食と医療の安全関わるプリオン病の市民講座プリオン病・口蹄疫・インフルエンザ・放射能
    • Place of Presentation
      福岡
    • Year and Date
      2011-10-23
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] プリオン病研究の最前線.2011

    • Author(s)
      堂浦 克美.
    • Organizer
      第16回日本神経感染症学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] ヤコブ病克服の基礎研究.2011

    • Author(s)
      堂浦 克美.
    • Organizer
      第5回食と医療の安全関わるプリオン病の市民講座 プリオン病・口蹄疫・インフルエンザ・放射能.
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] プリオン病研究の最前線2011

    • Author(s)
      堂浦克美
    • Organizer
      第16回日本神経感染症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Anti-Prion Activity of Protein-Bound Polysaccharide K in Prion-Infected Cells and Animals.2011

    • Author(s)
      Hamanaka T, Sakasegawa Y, Kimura T, Doh-ura K, Ando T, Ohmoto A.
    • Organizer
      Prion2011
    • Place of Presentation
      Montreal (Canada)
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] CC chemokines are upregulated in prion-infected neuroblastoma cells2010

    • Author(s)
      Sakasegawa Y, Nakabayashi S, Nishizawa K, Oguma A, Doh-ura K.
    • Organizer
      Asia-Oceania Symposium on Prion Diseases
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] A thioflavin derivative facilitates cross-linking of abnormal PrP but not normal PrP2010

    • Author(s)
      Teruya K, Doh-ura K.
    • Organizer
      Asia-Oceania Symposium on Prion Diseases
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] 熱ショック蛋白質Hsp90のリコンビナントプリオン蛋白質に対する部分変性活性は低濃度Cu(II)イオンによって可逆的に制御される2010

    • Author(s)
      逆瀬川裕二、堂浦克美
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] ヤコブ病の克服研究2010

    • Author(s)
      堂浦克美
    • Organizer
      第4回プリオン病の市民講座食と医療の安全
    • Place of Presentation
      東京
    • Year and Date
      2010-11-23
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Search for endogenous factors involved in the abnormal PrP formation in prion-infected cells2010

    • Author(s)
      Kimura T, Nishizawa K, Doh-ura K.
    • Organizer
      Asia-Oceania Symposium on Prion Diseases
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] Anti-prion activities of PSK in vitro and in vivo-further evaluation of its function-2010

    • Author(s)
      Hamanaka T, Sakasegawa Y, Oguma A, Nishizawa K, Doh-ura K.
    • Organizer
      Asia-Oceania Symposium on Prion Diseases
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] ヤコブ病の克服研究.第4回プリオン病の市民講座2010

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全-BSE・ヤコブ病・鳥インフルエンザ・口蹄疫-
    • Place of Presentation
      東京
    • Year and Date
      2010-11-23
    • Data Source
      KAKENHI-PROJECT-22390172
  • [Presentation] BF-227を用いたプリオンアミロイドイメージング-Gerstmann-Straussler-Scheinker病における画像と病理の対比-2008

    • Author(s)
      坪井義夫、田中美紀、岡村信行、志賀裕正、堂浦克美、本田裕之、佐々木健介、山田達夫
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プロテアーゼ抵抗性プリオン蛋白産生に関与する内因性因子2008

    • Author(s)
      木村朋寛、西村有起、堂浦克美
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] スクレイピーマウス血清中における疾患特異的蛋白質の検出2008

    • Author(s)
      戸邊美智子、宮庄拓、野村幸子、伊藤暁史、松田一哉、川崎ゆり、堂浦克美, 毛利資郎、横田博
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] プロテアーゼ抵抗性プリオン蛋白産生に関与する内因性因子2008

    • Author(s)
      木村朋寛, 西村有起, 堂浦克美
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 抗プリオン活性を有するアミロイド親和性化合物の構造的特徴2008

    • Author(s)
      濱中大一、川越敬一、陳忠正、照屋健太、堂浦克美
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] スクレイピーマウス血清中における疾患特異的蛋白質の検出2008

    • Author(s)
      戸邊美智子, 宮庄拓, 野村幸子, 伊藤暁史, 松田一哉, 川崎ゆり, 堂浦克美, 毛利資郎, 横田博
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヤコブ病克服プロジェクトの成果と課題-治療・発症機序研究2008

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全に関する市民講座「プリオンから見た食と医療の安全 : プリオンはもう怖くないの? ウシ海綿状脳症(BSE)とヤコブ病(CJD)」
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-14
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Characterization of the interaction between prion protein and heparin2008

    • Author(s)
      Teruya K, Yamada Y, Nishimura T, Suda Y, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] BF-227を用いたプリオンアミロイドイメージング-Gerstmann-Straussler-Scheinker病における画像と病理の対比-2008

    • Author(s)
      坪井義夫、田中美紀、岡村信行、志賀裕正、堂浦克美、本田裕之、佐々木健介、山田達夫
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] Binding of mouse prion protein to heparin2008

    • Author(s)
      Teruya K, Wakao T, Nishimura T, Kimura Y, Sakasegawa Y, Suda Y, Doh-ura K
    • Organizer
      Meeting of 17th Methods in Protein Structure Analysis (MPSA2008)
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Binding of mouse prion protein to heparin2008

    • Author(s)
      Teruya K, Wakao T, Nishimura T, Kimura Y, Sakasegawa Y, Suda Y, Doh-ura K
    • Organizer
      Meeting of 17th Methods in Protein Structure Analysis (MPSA2008)
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] 持続性プリオン感染細胞におけるPrPresの産生を抑制する新規ヒートショック蛋白質90阻害剤2008

    • Author(s)
      逆瀬川裕二, 堂浦克美
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヤコブ病克服プロジェクトの成果と課題-治療・発症機序研究2008

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全に関する市民講座「プリオンから見た食と医療の安全 : プリオンはもう怖くないの? ウシ海綿状脳症(BSE)とヤコブ病(CJD)」
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-14
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] Heat shock protein 90 (Hsp90) stimulates polymerization of a copper-loaded prion protein.2008

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      Prion2008
    • Place of Presentation
      Madrid (Spain)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 持続性プリオン感染細胞におけるPrPresの産生を抑制する新規ヒートショック蛋白質90阻害剤2008

    • Author(s)
      逆瀬川裕二、堂浦克美
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] Heat shock protein 90(Hsp90)stimulates polymerization of a copper-loaded prion protein2008

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      Prion2008
    • Place of Presentation
      Madrid
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] BF-227を用いたプリオンアミロイドイメージング-Gerstmann-Straussler- Scheinker病における画像と病理の対比-2008

    • Author(s)
      坪井義夫, 田中美紀, 岡村信行, 志賀裕正, 堂浦克美, 本田裕之, 佐々木健介, 山田達夫
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Heat shock protein 90 (Hsp90) stimulates polymerization of acooper-loaded prion protein2008

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      Prion2008
    • Place of Presentation
      Madrid (Spain)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヤコブ病克服プロジェクトの成果と課題-治療・発症機序研究2008

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全に関する市民講座
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-14
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 抗プリオン活性を有するアミロイド親和性化合物の構造的特徴2008

    • Author(s)
      濱中大一, 川越敬一, 陳忠正, 照屋健太, 堂浦克美
    • Organizer
      2008年プリオン研究会
    • Place of Presentation
      新得(北海道)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Binding of mouse prion protein to heparin2008

    • Author(s)
      Teruya K, Wakao T, Nishimura T, Kimura Y, Sakasegawa Y, Suda Y, Doh-ura K
    • Organizer
      Meeting of 17th Methods in Protein Structure Analysis(MPSA2008)
    • Place of Presentation
      Sapporo, August(26-29)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Screening for endogenous factors involved in the formation of protease resistant prion protein.2007

    • Author(s)
      Kimura T, Ishikawa K, Nishimura Y, Schatzl HM, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヘパリンとプリオン蛋白質相互作用のキャラクタリゼーション。2007

    • Author(s)
      照屋健太、山田有希、隅田泰生、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] 銅イオンにより誘起されるプリオンタンパク質の構造変化2007

    • Author(s)
      山口恭史, 三浦隆史, 照屋健太, 堂浦克美, 竹内英夫
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] フェオフィチン類の異常型プリオンタンパク質産生阻害機構の解明2007

    • Author(s)
      末吉 真, 樋口隆一, 堂浦克美, 宮本智文
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] The C-terminal chaperone domain of heat shock protein 90 kDa isresponsible for the conformational modification ofcopper-loaded recombinant prion protein.2007

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ペントサンポリサルフェート脳室内持続投与療法の臨床研究-11例の臨床経過と問題点。2007

    • Author(s)
      坪井義夫、山田達夫、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病への治療アプローチ。2007

    • Author(s)
      堂浦克美
    • Organizer
      第25回日本神経治療学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ウシ海綿状脳症罹患牛血清に検出されたグリア線維性酸性蛋白質に対する自己抗体2007

    • Author(s)
      野村幸子, 宮庄 拓, 戸邉美智子, 志賀康弘, 前田尚之, 堂浦克美, 横田 博
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 銅イオンにより誘起されるプリオンタンパク質の構造変化。2007

    • Author(s)
      山口恭史、三浦隆史、照屋健太、堂浦克美、竹内英夫
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] 抗プリオン活性を持つ担子菌成分に関する研究2007

    • Author(s)
      濱中大一, 堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Development of potential therapeutics for prion diseases2007

    • Author(s)
      Doh-ura K
    • Organizer
      CJD Foundation Family Conference
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病の治療の試み。2007

    • Author(s)
      堂浦克美
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Development of potential therapeutics for prion diseases.2007

    • Author(s)
      Doh-ura K
    • Organizer
      CJD Foundation Family Conference
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] C 末端をコレステロールで修飾した蛋白質の半合成と細胞膜への結合。2007

    • Author(s)
      照屋健太、山田有希、西澤桂子、堂浦克美
    • Organizer
      第44回ペプチド討論会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ペントサンポリサルフェート脳室内持続投与療法の臨床研究-11例の臨床経過と問題点2007

    • Author(s)
      坪井義夫, 山田達夫, 堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Amyloidophilic chemicals for therapeutics of prion diseases.2007

    • Author(s)
      Doh-ura K
    • Organizer
      CJD2007
    • Place of Presentation
      Vancouver
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヒト由来のグルタミン酸受容体GluR5リガンド結合部位の結晶構造解析。2007

    • Author(s)
      篠原正将、海野昌喜、照屋健太、酒井隆一、堂浦克美、佐々木 誠、齋藤正男
    • Organizer
      第22回生体機能関連化学シンポジウム「若手フオーラム」
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病の治療の試み。2007

    • Author(s)
      堂浦克美
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヤコブ病克服プロジェクトの成果と残されている課題-治療・発症機序研究。2007

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全に関する市民講座「プリオンから見た食の安全と医療の安全:プリオンはもう怖くないの?ウシ海綿状脳症(BSE)とヤコブ病(CJD)」
    • Place of Presentation
      東京
    • Year and Date
      2007-12-16
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] HSP90 family proteins modify the comformation of copper-loaded prion protein in a nucleotide-dependent manner.2007

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プロテアーゼ抵抗性プリオン蛋白産生に関与する内因性因子のスクリーニング。2007

    • Author(s)
      木村朋寛、石川謙介、西村有起、Schatzl HM、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病-診断・治療研究の最近の進歩と課題-2007

    • Author(s)
      堂浦克美
    • Organizer
      第12回SRL感染症フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 抗プリオン活性を持つ担子菌成分に関する研究。2007

    • Author(s)
      濱中大一、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病への治療アプローチ2007

    • Author(s)
      堂浦克美
    • Organizer
      第25回日本神経治療学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Screening for endogenous factors involved in the formation of protease resistant prion protein2007

    • Author(s)
      Kimura T, Ishikawa K, Nishimura Y, Schatzl HM, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病への治療アプローチ。2007

    • Author(s)
      堂浦克美
    • Organizer
      第25回日本神経治療学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] The C-terminal chaperone domain of heat shock protein 90 kDa is responsible for the conformational modification of copper-loaded recombinant prion protein2007

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Amyloidophilic chemicals for therapeutics of prion diseases2007

    • Author(s)
      Doh-ura K
    • Organizer
      CJD2007
    • Place of Presentation
      Vancouver
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] HSP90 family proteins modify the comformation of copper-loaded prion protein in a nucleotide-dependent manner2007

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヤコブ病克服プロジェクトの成果と残されている課題-治療・発症機序研究。2007

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全に関する市民講座「プリオンから見た食の安全と医療の安全:プリオンはもう怖くないの? ウシ海綿状脳症(BSE)とヤコブ病(CJD)」
    • Place of Presentation
      東京
    • Year and Date
      2007-12-16
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Characterization of the interaction between prion protein and heparin.2007

    • Author(s)
      Teruya K, Yamada Y, Nishimura T, Suda Y, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヒト由来のグルタミン酸受容体GluR5 リガンド結合部位の結晶構造解析2007

    • Author(s)
      篠原正将, 海野昌喜, 照屋健太, 酒井隆一, 堂浦克美, 佐々木 誠, 齋藤正男
    • Organizer
      第22回生体機能関連化学シンポジウム「若手フォーラム」
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] The C-terminal chaperone domain of heat shock protein 90 kDa is responsible for the conformational modification of copper-loaded recombinant prion protein.2007

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヒト由来のグルタミン酸受容体GluR5リガンド結合部位の結晶構造解析。2007

    • Author(s)
      篠原正将、海野昌喜、照屋健太、酒井隆一、堂浦克美、佐々木 誠、齋藤正男
    • Organizer
      第22回生体機能関連化学シンポジウム「若手フォーラム」
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] 抗プリオン活性を持つ担子菌成分に関する研究。2007

    • Author(s)
      濱中大一、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] フェオフィチン類の異常型プリオンタンパク質産生阻害機構の解明。2007

    • Author(s)
      末吉 真、樋口隆一、堂浦克美、宮本智文
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] Screening for endogenous factors involved in the formation of protease resistant prion protein.2007

    • Author(s)
      Kimura T, Ishikawa K, Nishimura Y, Schatzl HM, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] プロテアーゼ抵抗性プリオン蛋白産生に関与する内因性因子のスクリーニング。2007

    • Author(s)
      木村朋寛、石川謙介、西村有起、Schatzl HM、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヘパリンとプリオン蛋白質相互作用のキャラクタリゼーション。2007

    • Author(s)
      照屋健太、山田有希、隅田泰生、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン感染細胞からの迅速なPrPres回収法。2007

    • Author(s)
      照屋健太、魚本 幸、藤田智司、堂浦克美
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] プリオン感染細胞からの迅速なPrPres回収法2007

    • Author(s)
      照屋健太, 魚本 幸, 藤田智司, 堂浦克美
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン感染細胞からの迅速なPrPres回収法。2007

    • Author(s)
      照屋健太、魚本 幸、藤田智司、堂浦克美
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ウシ海綿状脳症罹患牛血清に検出されたグリア線維性酸性蛋白質に対する自己抗体。2007

    • Author(s)
      野村幸子、宮庄 拓、戸邉美智子、志賀康弘、前田尚之、堂浦克美、横田 博
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 末梢で異常型プリオン蛋白の形成に関与するリンパ球サブセット。2007

    • Author(s)
      川崎ゆり、河原佐智代、宮澤正顕、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] C末端をコレステロールで修飾した蛋白質の半合成と細胞膜への結合。2007

    • Author(s)
      照屋健太、山田有希、西澤桂子、堂浦克美
    • Organizer
      第44回ペプチド討論会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] Development of potential therapeutics for prion diseases.2007

    • Author(s)
      Doh-ura K
    • Organizer
      CJD Foundation Family Conference
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ペントサンポリサルフェート脳室内持続投与療法の臨床研究-11例の臨床経過と問題点。2007

    • Author(s)
      坪井義夫、山田達夫、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] C 末端をコレステロールで修飾した蛋白質の半合成と細胞膜への結合2007

    • Author(s)
      照屋健太, 山田有希, 西澤桂子, 堂浦克美
    • Organizer
      第44回ペプチド討論会
    • Place of Presentation
      富山市
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病-診断・治療研究の最近の進歩と課題-。2007

    • Author(s)
      堂浦克美
    • Organizer
      第12回SRL感染症フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヒト由来のグルタミン酸受容体GluR5 リガンド結合部位の結晶構造解析2007

    • Author(s)
      篠原正将, 海野昌喜, 照屋健太, 酒井隆一, 堂浦克美, 佐々木 誠, 齋藤正男
    • Organizer
      第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] HSP90 family proteins modify the comformation of copper-loaded prion protein in a nucleotide-dependent manner.2007

    • Author(s)
      Sakasegawa Y, Hachiya NS, Kaneko K, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] フェオフィチン類の異常型プリオンタンパク質産生阻害機構の解明。2007

    • Author(s)
      末吉 真、樋口隆一、堂浦克美、宮本智文
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 末梢で異常型プリオン蛋白の形成に関与するリンパ球サブセット。2007

    • Author(s)
      川崎ゆり、河原佐智代、宮澤正顕、堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヘパリンとプリオン蛋白質相互作用のキャラクタリゼーション2007

    • Author(s)
      照屋健太, 山田有希, 隅田泰生, 堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ヤコブ病克服プロジェクトの成果と残されている課題-治療・発症機序研究2007

    • Author(s)
      堂浦克美
    • Organizer
      食と医療の安全に関する市民講座「プリオンから見た食の安全と医療の安全 : プリオンはもう怖くないの? ウシ海綿状脳症(BSE)とヤコブ病(CJD)」
    • Place of Presentation
      東京
    • Year and Date
      2007-12-16
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Characterization of the interaction between prion protein and heparin.2007

    • Author(s)
      Teruya K, Yamada Y, Nishimura T, Suda Y, Doh-ura K
    • Organizer
      Prion2007
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プリオン病-診断・治療研究の最近の進歩と課題-。2007

    • Author(s)
      堂浦克美
    • Organizer
      第12回SRL感染症フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] プリオン病の治療の試み2007

    • Author(s)
      堂浦克美
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 銅イオンにより誘起されるプリオンタンパク質の構造変化。2007

    • Author(s)
      山口恭史、三浦隆史、照屋健太、堂浦克美、竹内英夫
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] プロテアーゼ抵抗性プリオン蛋白産生に関与する内因性因子のスクリーニング2007

    • Author(s)
      木村朋寛, 石川謙介, 西村有起, Schatzl HM, 堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] Amyloidophilic chemicals for therapeutics of prion diseases.2007

    • Author(s)
      Doh-ura K
    • Organizer
      CJD2007
    • Place of Presentation
      Vancouver
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] 末梢で異常型プリオン蛋白の形成に関与するリンパ球サブセット2007

    • Author(s)
      川崎ゆり, 河原佐智代, 宮澤正顕, 堂浦克美
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] ウシ海綿状脳症罹患牛血清に検出されたグリア線維性酸性蛋白質に対する自己抗体。2007

    • Author(s)
      野村幸子、宮庄 拓、戸邉美智子、志賀康弘、前田尚之、堂浦克美、横田 博
    • Organizer
      2007年プリオン研究会
    • Place of Presentation
      津南(新潟)
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヒト由来のグルタミン酸受容体GluR5リガンド結合部位の結晶構造解析。2007

    • Author(s)
      篠原正将、海野昌喜、照屋健太、酒井隆一、堂浦克美、佐々木 誠、齋藤正男
    • Organizer
      第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18659253
  • [Presentation] ヒト由来のグルタミン酸受容体GluR5 リガンド結合部位の結晶構造解析。2007

    • Author(s)
      篠原正将、海野昌喜、照屋健太、酒井隆一、堂浦克美、佐々木 誠、齋藤正男
    • Organizer
      第80回目本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390234
  • [Presentation] A platinum compound enhances the protease sensitivity of PrPres in cell lysates.

    • Author(s)
      Sakasegawa Y, Doh-ura K.
    • Organizer
      Asian Pacific Prion Symposium 2014
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2014-07-06 – 2014-07-07
    • Data Source
      KAKENHI-PROJECT-24659424
  • 1.  SAKASEGAWA Yuji (90418616)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 26 results
  • 2.  TERUYA Kenta (30372288)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 39 results
  • 3.  IWAKI Toru (40221098)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  鈴木 伸之
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OGOMORI Koji (40211817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YOKOTA Hiroshi (90137414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MORI Seiichi (10390824)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  片峰 茂 (40161062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  金子 清俊 (10251513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  小野寺 節 (90012781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  福岡 伸一 (20183923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  堀内 基広 (30219216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  北本 哲之 (20192560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  山田 達夫 (60159217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  福島 武雄 (10078735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  山本 正昭 (80240125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  坪井 義夫 (90291822)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  松島 俊夫 (40165816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  安東 由喜雄 (20253742)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  吉良 潤一 (40183305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  太田 茂 (60160503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NISHIZAWA Keiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 23.  OGUMA Ayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 24.  村田 充男
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SASAKI Kensuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  佐々木 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  坂口 末廣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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