Mise Setsuko 三瀬節子

… Alternative Names

三瀬節子ミセセツコ

Mise-Omata Setsuko 三瀬節子

MISE Setsuko 三瀬節子

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Researcher Number	00269052
Other IDs
Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 助教
Affiliation (based on the past Project Information) *help	2023: 東京理科大学, 研究推進機構生命医科学研究所, 助教 2019 – 2021: 慶應義塾大学, 医学部(信濃町), 助教 2016 – 2018: 慶應義塾大学, 医学部(信濃町), 特任助教 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 非常勤講師 2013: 独立行政法人理化学研究所, バイオリソースセンター, 開発研究員 2009 – 2012: 独立行政法人理化学研究所, 生体情報統合技術開発チーム, 開発研究員 2004: 独立行政法人理化学研究所, 生体情報総合技術開発チーム, 開発研究員
Review Section/Research Field	Principal Investigator Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49030:Experimental pathology-related / Orthopaedic surgery Except Principal Investigator Hematology / Biological Sciences
Keywords	Principal Investigator 骨芽細胞 / マクロファージ / NF-kB / 造血幹細胞ニッチ / 骨代謝 / エフェクター / CAR-T細胞 / エフェクター細胞 / サイトカイン / 腫瘍免疫 … More / 放射線 / 造血幹細胞移植 / IL-6 / 疲弊化T細胞 / 低分子化合物 / SOCSファミリー分子 / サイトカインシグナル / IL-21 / SOCS3 / IL6 / 制御性T細胞 / ミトコンドリア / 代謝 / T細胞 / 移植・再生医療 / 免疫学 / NF-ｋB / インフラマソーム / Spred / 脂肪細胞 / オステオマック / 炎症性サイトカイン / 炎症 / 破骨細胞 / 造血幹細胞 / 転写因子 / 血球分化 / プロスタグランジンE2 / 骨髄マクロファージ … More Except Principal Investigator NF-kB / マクロファージ / リンパ球 / 造血機構 / Apopotsis / Maturation arrest / Macrophage / Lymphocyte / Apoptosis / Macrophages Maturation / phocytes / Lym / Hematopoiesis / c-Rel / RelA / Brca1 / 遺伝子発現プロファイリング / TNF耐性 / TNF / RelAサブユニット Less

Therapeutic approach to confer an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine in effector T cellsPrincipal Investigator
- Principal Investigator
  
  三瀬節子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo University of Science
Enhancement of anti-tumor response by augmentation by cytokine signaling.Principal Investigator
- Principal Investigator
  
  Mise-Omata Setsuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Keio University
Repairing of heamatopoietic niche in bone marrow after X-ray irradiationPrincipal Investigator
- Principal Investigator
  
  Mise-Omata Setsuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Keio University
The dysfunction of macrophages/osteoclast precursors in bone metabolism after transplantation with RelA-deficient HSC.Principal Investigator
- Principal Investigator
  
  Mise-Omata Setsuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical and Dental University
  Institute of Physical and Chemical Research
Role of NF-kB RelA in homeostasis of bone and hematopoietic nichePrincipal Investigator
- Principal Investigator
  
  MISE Setsuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The Institute of Physical and Chemical Research
Elucidation of immune regulation mechanisms by NF-kB for development of lymphocytes and macrophages.
- Principal Investigator
  
  DOI Takahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The Institute of Physical and Chemical Research
腫瘍壊死因子(TNF)、転写因子NFκB経路によるがん化防御機構の解析
- Principal Investigator
  
  DOI Takahiro
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009

All Journal Article Presentation Book

[Book] Biology in Stem Cell Niche.2015
- Author(s)
  Mise-Omata, S., Doi, TS, Aoki K., Obata Y.
- Total Pages
  14
- Publisher
  Springer Humana Press
- Data Source
  KAKENHI-PROJECT-25462392
[Journal Article] NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment2024
- Author(s)
  Srirat Tanakorn、Hayakawa Taeko、Mise-Omata Setsuko、Nakagawara Kensuke、Ando Makoto、Shichino Shigeyuki、Ito Minako、Yoshimura Akihiko
- Journal Title
  
  Cell Reports
  
  Volume: 43 Issue: 3 Pages: 113898-113898
- DOI
  10.1016/j.celrep.2024.113898
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06723, KAKENHI-PROJECT-22K19444, KAKENHI-PROJECT-22K20778, KAKENHI-PUBLICLY-23H04785, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-21H02719
[Journal Article] SOCS3 deletion in effector T?cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine2023
- Author(s)
  Mise-Omata Setsuko、Ando Makoto、Srirat Tanakorn、Nakagawara Kensuke、Hayakawa Taeko、Iizuka-Koga Mana、Nishimasu Hiroshi、Nureki Osamu、Ito Minako、Yoshimura Akihiko
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 112940-112940
- DOI
  10.1016/j.celrep.2023.112940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06723, KAKENHI-PROJECT-22K19444, KAKENHI-PROJECT-22K20778, KAKENHI-PUBLICLY-23H04785, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-21H02719
[Journal Article] Cellular and Humoral Immune Responses after Breakthrough Infection in Patients Undergoing Hemodialysis2023
- Author(s)
  Toda Masataro、Yoshifuji Ayumi、Nakayama Tetsuo、Mise-Omata Setsuko、Oyama Emi、Uwamino Yoshifumi、Namkoong Ho、Komatsu Motoaki、Yoshimura Akihiko、Hasegawa Naoki、Kikuchi Kan、Ryuzaki Munekazu
- Journal Title
  
  Vaccines
  
  Volume: 11 Issue: 7 Pages: 1214-1214
- DOI
  10.3390/vaccines11071214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06723
[Journal Article] SOCS: negative regulators of cytokine signaling for immune tolerance2021
- Author(s)
  Akihiko Yoshimura, Minako Ito, Setsuko Mise-Omata, Makoto Ando
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 711-716
- DOI
  10.1093/intimm/dxab055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07514, KAKENHI-PROJECT-19J21508
[Journal Article] サイトカインストームとT細胞疲弊　コロナウィルス感染を中心に2021
- Author(s)
  三瀬節子、安藝大輔、池田真理、吉村昭彦
- Journal Title
  
  実験医学
  
  Volume: 39 Pages: 505-511
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07514
[Journal Article] T 細胞のエピジェネティック改変による免疫疾患制御2021
- Author(s)
  吉村昭彦、中司寛子、三瀬節子
- Journal Title
  
  炎症と免疫
  
  Volume: 29 Pages: 533-539
- Data Source
  KAKENHI-PROJECT-19K07514
[Journal Article] Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand.2021
- Author(s)
  Makoto Ando; Taisuke Kondo; Wataru Tomisato; Minako Ito; Shigeyuki Shichino; Tanakorn Srirat; Setsuko Mise-Omata; Kensuke Nakagawara ; Akihiko Yoshimura
- Journal Title
  
  Cancer Research Communications
  
  Volume: 1 Issue: 1 Pages: 41-55
- DOI
  10.1158/2767-9764.crc-21-0034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07514, KAKENHI-PROJECT-19J21508
[Journal Article] The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells.2020
- Author(s)
  Kondo T, Ando M, Nagai N, Tomisato W, Srirat T, Liu B, Mise-Omata S, Ikeda M, Chikuma S, Nishimasu H, Nureki O, Ohmura M, Hayakawa N, Hishiki T, Uchibori R, Ozawa K, Yoshimura A
- Journal Title
  
  Cancer Res
  
  Volume: 80 Issue: 3 Pages: 471-483
- DOI
  10.1158/0008-5472.can-19-1196
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07488, KAKENHI-PROJECT-19K07514, KAKENHI-PROJECT-19K23850, KAKENHI-PUBLICLY-19H04816, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-18K15290, KAKENHI-PROJECT-16H06276
[Journal Article] 核内受容体NR4aによるT細胞疲弊と免疫寛容の制御2020
- Author(s)
  安藤　眞、三瀬節子、大谷木正貴、吉村昭彦
- Journal Title
  
  実験医学
  
  Volume: 38 Pages: 3178-3306
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07514
[Journal Article] 抗腫瘍免疫におけるT細胞の疲弊とその回避2020
- Author(s)
  三瀬節子、大谷木正貴、吉村昭彦
- Journal Title
  
  腫瘍内科
  
  Volume: 26 Pages: 694-701
- NAID
  40022446757
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07514
[Journal Article] Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery2019
- Author(s)
  Ito Minako、Komai Kyoko、Mise-Omata Setsuko、Iizuka-Koga Mana、Noguchi Yoshiko、Kondo Taisuke、Sakai Ryota、Matsuo Kazuhiko、Nakayama Takashi、Yoshie Osamu、Nakatsukasa Hiroko、Chikuma Shunsuke、Shichita Takashi、Yoshimura Akihiko
- Journal Title
  
  Nature
  
  Volume: 565 Issue: 7738 Pages: 246-250
- DOI
  10.1038/s41586-018-0824-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15129, KAKENHI-PROJECT-18K15198, KAKENHI-PUBLICLY-17H05514, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H05096, KAKENHI-PROJECT-16J30001, KAKENHI-PROJECT-16K08847, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-17K19571, KAKENHI-PROJECT-17K15667, KAKENHI-PROJECT-17H06175, KAKENHI-PROJECT-20K20384
[Journal Article] Inhibition of Nr4a receptors enhances anti-tumor immunity by breaking Treg-mediated immune tolerance2018
- Author(s)
  Sana Hibino, Shunsuke Chikuma, Taisuke Kondo, Minako Ito, Hiroko Nakatsukasa, Setsuko Omata-Mise, and Akihiko Yoshimura,
- Journal Title
  
  Cancer Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09867
[Journal Article] Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy.2018
- Author(s)
  Taisuke Kondo Yuki Imura Shunsuke Chikuma Sana Hibino Setsuko Omata‐Mise Makoto Ando Takashi Akanuma Mana Iizuka Ryota Sakai Rimpei Morita Akihiko Yoshimura
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 7 Pages: 2130-2140
- DOI
  10.1111/cas.13648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15290, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-16H05178
[Journal Article] Inhibition of Nr4a receptors enhances anti-tumor immunity by breaking Treg-mediated immune tolerance.2018
- Author(s)
  Hibino S, Chikuma S, Kondo T, Ito M, Nakatsukasa H, Omata-Mise S, Yoshimura A
- Journal Title
  
  Cancer Res
  
  Volume: Epub Issue: 11 Pages: 3027-3040
- DOI
  10.1158/0008-5472.can-17-3102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-15J07566, KAKENHI-PROJECT-18K15198, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-20K20384
[Journal Article] Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy.2017
- Author(s)
  Chikuma S, Kanamori M, Mise-Omata S, Yoshimura A.
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Issue: 4 Pages: 574-580
- DOI
  10.1111/cas.13194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08847, KAKENHI-PROJECT-16K09867
[Journal Article] Delivery of RANKL-Binding Peptide OP3-4 Promotes BMP-2-Induced Maxillary Bone Regeneration.2016
- Author(s)
  Uehara T, Mise-Omata S, Matsui M, Tabata Y, Murali R, Miyashin M, Aoki K.
- Journal Title
  
  J Dent Res.
  
  Volume: 95 Issue: 6 Pages: 665-672
- DOI
  10.1177/0022034516633170
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462392, KAKENHI-PROJECT-25293377, KAKENHI-PROJECT-16K09867
[Journal Article] Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.2016
- Author(s)
  Sugamori Y, Mise-Omata S, Maeda C, Aoki S, Tabata Y, Murali R, Yasuda H, Udagawa N, Suzuki H, Honma M, Aoki K.
- Journal Title
  
  Bioessays
  
  Volume: 38 Issue: 8 Pages: 717-725
- DOI
  10.1002/bies.201600104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K11818
[Journal Article] Peptide-induced de novo bone formation after tooth extraction prevents alveolar bone loss in a murine tooth extraction model.2016
- Author(s)
  Arai Y, Aoki K, Shimizu Y, Tabata Y, Ono T, Murali R, Mise-Omata S, Wakabayashi N
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 782 Pages: 89-97
- DOI
  10.1016/j.ejphar.2016.04.049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462392, KAKENHI-PROJECT-26861771, KAKENHI-PROJECT-16K09867
[Journal Article] The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: A bone histomorphometric study.2015
- Author(s)
  Kato G, Shimizu Y, Arai Y, Suzuki N, Sugamori Y, Maeda M, Takahashi M, Tamura Y, Wakabayashi N, Murali R, Ono T, Ohya K, Mise-Omata S, Aoki K.
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: Sep 12 Issue: 1 Pages: 251-264
- DOI
  10.1186/s13075-015-0753-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861771, KAKENHI-PROJECT-25462392, KAKENHI-PROJECT-25861753, KAKENHI-PROJECT-25293377
[Journal Article] The NF-kB RelA subunit confers resistance to Leishmania major by inducing NOS2 and Fas expression but not Th1 differentiation2009
- Author(s)
  S. Mise, T. Doi, et al
- Journal Title
  
  Journal of Immunology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591254
[Journal Article] The NF-kB RelA subunit confers resistance to Leishmania major by inducing NOS2 and Fas expression but not Th1 differentiation2009
- Author(s)
  三瀬節子、土井貴裕
- Journal Title
  
  Journal of Immunology 182
  
  Pages: 4910-4916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] T 細胞で SOCS3 を欠損したマウスでは IL6 のシグナルの亢進により抗腫瘍作用が増強する2021
- Author(s)
  三瀬　節子、吉村　昭彦
- Organizer
  第 25 回がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K07514
[Presentation] 腫瘍免疫における T 細胞疲弊のメカニズム2021
- Author(s)
  吉村　昭彦、Tanakorn SRIRAT、安藤眞、三瀬　節子
- Organizer
  第 25 回がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07514
[Presentation] Augmentation of IL6 signaling by the deletion of SOCS3 in T cells enhances tumor immunity through the modification of mitochondria states2021
- Author(s)
  Setsuko Mise-Omata, Akihiko Yoshimura
- Organizer
  第 50 回日本免疫学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07514
[Presentation] Blockade of suppressor of cytokine signaling 3 enhances anti-tumor immunity2018
- Author(s)
  Setsuko Mise-Omata and Akihiko Yoshimura
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-16K09867
[Presentation] 放射線照射後の骨髄内環境の修復における骨髄マクロファージの役割2016
- Author(s)
  三瀬節子
- Organizer
  第2回骨免疫学会
- Place of Presentation
  ホテルモントレ沖縄スパ&リゾート（沖縄県恩納村）
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-16K09867
[Presentation] A pharmacological role of metallothionein in zinc-treated cartilage-progenitor cells.2016
- Author(s)
  Yukihiko Tamura, Setsuko Mise, Yasutaka Sugamori, Md. Zahirul Haq Bhuyan, Mariko Takahashi, Tomoki Uehara, Yuki Arai, Michiyo Miyashin, Noriyuki Wakabayashi, Kazuhiro Aoki.
- Organizer
  APFP 2016(The 13th Asia Pacific Federation of Pharmacologists Meeting)
- Place of Presentation
  Bangkok(Thailand)
- Year and Date
  2016-02-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462392
[Presentation] A rankl-binding peptide accelerates BMP-induced bone regeneration in murine maxilla by subperiosteal injections.:2015
- Author(s)
  Uehara T, Mise S, Arai Y, Sugamori Y, Kato G, Tamura Y, Tabata Y, Murali R, Wakabayashi N, Miyashin M, Aoki K.
- Organizer
  13th Congress of the Internatitonal Society of Bone Morphometry.
- Place of Presentation
  東京（東京ガーデンパレスホテル）
- Year and Date
  2015-04-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462392
[Presentation] 亜鉛処理による軟骨前駆細胞(ATDC5)におけるメタロチオンネインの発現について2015
- Author(s)
  32.田村幸彦、三瀬節子、菅森泰隆、Md Zahirul Haque Bhuyan、高橋真理子、上原智己、新井祐貴、宮新美智世、若林則幸、青木和広.
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  千葉(柏市、柏の葉カンファレンスセンター)
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25462392
[Presentation] マウス抜歯窩に局所適用したRANKL結合ペプチドとBMP-2の併用による骨形成促進作用の評価.2015
- Author(s)
  新井祐貴、青木和広、三瀬節子、清水康広、小野卓史、若林則幸.
- Organizer
  第35回日本骨形態計測学会
- Place of Presentation
  倉敷（倉敷市芸文館）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-25462392
[Presentation] NF-kB rela-deficient macrophages fail to support bone formation and maitain the microenvironment for hematopoiesis after X-ray irradiation and HSC transplantation.2013
- Author(s)
  三瀬　節子
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] NF-kappaB, rela-deficient bone marrow macrophages fail to support bone formation and maintain HSC niche after lethal irradiation and HSC tranplantation.2013
- Author(s)
  Setsuko Mise－Omata, Neil Alles, Taro Fukazawa, Kazuhiro Aoki, Keiichi Ohya, Eijiro Jimi, Yuichi Obata, Takahiro Doi
- Organizer
  The joint international meeting of the 78th meeting of the japanese society of interferon and cytokine research and The 21st international symposium on Molecular cell biology of macrophages 2013
- Place of Presentation
  東京　日本
- Data Source
  KAKENHI-PROJECT-25462392
[Presentation] NF-kaｐpaB rela-deficient macrophages fail to support bone formation and maintain the microenvironment for hematopoiesis after X-ray irradiation and HSC transplantation.2013
- Author(s)
  Setsuko Mise-Omata,Taro Fukazawa, Yuichi Obata, Takahiro Doi
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-25462392
[Presentation] NF-κB, rela-deficient bone marrow macrophages fail to support bone formation and maintain HSC niche after lethal irradiation and HSC transplantation2013
- Author(s)
  Setsuko Mise-Omata, Neil Alles, Taro Fukazawa, Kazuhiro Aoki, Keiichi Ohya, Eijiro Jimi, Yuichi Obata, and Takahiro Doi
- Organizer
  JSICR-MMCB 2013
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] NF-kappaB, rela-deficient bone marrow macrophages fail to support bone formation and maintain HSC niche after lethal irradiation and HSC transplantation.2013
- Author(s)
  三瀬　節子
- Organizer
  第78回日本インターフェロン・サイトカイン学会総会（JSICR）　　第21回マクロファージ分子細胞生物学国際シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] rela-deficient osteal tissue macrophages (osteomac) are not able to support bone formation, resulting in impairment of microenvironment for hematopoiesis.2012
- Author(s)
  三瀬　節子
- Organizer
  日本免疫学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] rela-deficient osteal tissue macrophages (osteomac) are not able to support bone formation, resulting in impairment of microenvironment for hematopoiesis2012
- Author(s)
  Setsuko Mise-Omata, Taro Fukazawa, Yuichi Obata and Takahiro Doi
- Organizer
  日本免疫学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] Fukazawa, Yuichi Obata, and Takahiro Doi. NF-κB rela-deficient hematopoietic cells developed osteoporosis and poor activity of hematopoietic stem cells2011
- Author(s)
  Setsuko Mise-Omata, Taro Fukazawa, Yuichi Obata, and Takahiro Doi
- Organizer
  日本免疫学会総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] NF-kB/RelA subunit plays the critical roles on erythropoiesis2011
- Author(s)
  土井貴裕、三瀬節子
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] The precursor of NF-kB2 p100 acta as a cytoplasmic inhibitor of c-Rel, reducing the expression of IL-23 p19 subunits in dendritic cells2011
- Author(s)
  三瀬節子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] RelA欠損造血細胞は骨粗鬆症と造血異常を引き起こす2011
- Author(s)
  三瀬節子
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] NF-kB/RelA positively functions on transcriptional activation of Foxp3 with TGF-b signaling2010
- Author(s)
  土井貴裕、三瀬節子
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] Deficiency of NF-κB/RelA molecule in hematopoietic cells impairs lymphocyte development and bone metabolism : a possibility on a damage of hematopoietic niche.2010
- Author(s)
  Setsuko Mise-Omata
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  日本、神戸
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] Deficiency of NF-κB/RelA molecule in hematopoietic cells impairs lymphocyte development and bone metabolism: a possibility on a damage of hematopoietic niche2010
- Author(s)
  Setsuko Mise-Omata, Taro Fukazawa, Yuichi Obata and Takahiro Doi
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation] 転写因子NF-kBのRelAによって制御される血球分化と骨のリモデリング2010
- Author(s)
  三瀬節子
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] 転写因子NF-κBのRelAによって制御される血球分化と骨のリモデリング2010
- Author(s)
  三瀬節子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会、合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22591073
[Presentation]2010
- Author(s)
  三瀬節子
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] The evidence that precursor of p52 NF-kB2(p100)negatively regulate c-Rel function in IL-23 expression2009
- Author(s)
  三瀬節子
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] RelA欠損マウスでのリンパ球発生能力の再検討2009
- Author(s)
  三瀬節子
- Organizer
  日本免疫学会
- Place of Presentation
  グランキューブ大阪(大阪)
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21591254
[Presentation] Deficiency of NF-kB/RelA subunit and tumor necrosis factor(TNF) both cause abnormal hamatopoiesis.2009
- Author(s)
  土井貴裕、三瀬節子
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21591254

1. DOI Takahiro (60227684)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 青木和広 (40272603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 吉村昭彦 (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. YASUHIRO Shimizu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 土井了

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
6. 竹馬俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 宇田川信之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 近藤泰介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 駒井恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mise Setsuko 三瀬 節子

三瀬 節子 ミセ セツコ

Mise-Omata Setsuko 三瀬 節子

MISE Setsuko 三瀬 節子

Research Projects

Research Products

Co-Researchers

Therapeutic approach to confer an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine in effector T cellsPrincipal Investigator

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Enhancement of anti-tumor response by augmentation by cytokine signaling.Principal Investigator

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Repairing of heamatopoietic niche in bone marrow after X-ray irradiationPrincipal Investigator

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The dysfunction of macrophages/osteoclast precursors in bone metabolism after transplantation with RelA-deficient HSC.Principal Investigator

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Role of NF-kB RelA in homeostasis of bone and hematopoietic nichePrincipal Investigator

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Elucidation of immune regulation mechanisms by NF-kB for development of lymphocytes and macrophages.

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腫瘍壊死因子(TNF)、転写因子NFκB経路によるがん化防御機構の解析

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[Book] Biology in Stem Cell Niche.2015

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[Journal Article] NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment2024

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[Journal Article] SOCS3 deletion in effector T?cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine2023

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[Journal Article] Cellular and Humoral Immune Responses after Breakthrough Infection in Patients Undergoing Hemodialysis2023

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[Journal Article] SOCS: negative regulators of cytokine signaling for immune tolerance2021

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[Journal Article] サイトカインストームとT細胞疲弊 コロナウィルス感染を中心に2021

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[Journal Article] T 細胞のエピジェネティック改変による免疫疾患制御2021

Author(s)

Mise Setsuko 三瀬節子

三瀬節子ミセセツコ

Mise-Omata Setsuko 三瀬節子

MISE Setsuko 三瀬節子

[Journal Article] サイトカインストームとT細胞疲弊　コロナウィルス感染を中心に2021