AKAGI Masao 赤木将男

Researcher Number	00273441
Other IDs
Affiliation *help	2010 – 2017 : Kinki University, 医学部, 教授 2006 – 2007 : 近畿大, 医学部, 助教授 2007 : Kinki University, School of Med., Associate Professor 2004 – 2006 : Kinki University, School of Med., Associate Professor, 医学部, 助教授 2005 : 近畿大, 医学部, 教授 … More
Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery
Keywords	Principal Investigator 骨粗鬆症 / 親規遺伝子 / つくば高血圧マウス / レニン・アンジオテンシン系 / 変形性膝関節症 / ATDC5細胞 / Differential Display法 Except Principal Investigator 末梢神経再生 / 変形性膝関節症 / 骨髄幹細胞 … More

Artificial nerves containing allogenic basal lamellae scaffold and bone marrow derived stem cellsOngoing
- Principal Investigator
  
  柿木良介
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
局所的レニン・アンギオテンシン系（RAS）活性化による関節軟骨変性の機序の解明Principal InvestigatorOngoing
- Principal Investigator
  
  赤木將男
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
骨髄間葉系幹細胞移植した同種脱細胞化神経片含有血管柄入りチューブ内での神経再生Ongoing
- Principal Investigator
  
  柿木良介
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
Effects of local Renin-angiotensin system on development and progression of knee osteoarthritis(OA)Principal Investigator
- Principal Investigator
  
  AKAGI Masao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
Involvement of the oxidized low-density lipoprotein/lectin-like oxidized low-density lipoprotein receptor-1 system to joint cartilage degenerationPrincipal Investigator
- Principal Investigator
  
  AKAGI Masao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
Effects of Hyperlipidemia on Progression of Knee OsteoarthritisPrincipal Investigator
- Principal Investigator
  
  AKAGI Masao
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
Mechanism of hyaluronan depolymerization due to Reactive oxygen species (ROS) produced by synoviocytes cultured in hypoxia, resulting synovial proliferation.Principal Investigator
- Principal Investigator
  
  AKAGI Masao
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kinki University
Differential Display法による軟骨発生分化制御因子のクローニングPrincipal Investigator
- Principal Investigator
  
  赤木将男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Development of a new strategy of hyperthermia for metastatic bone tumor
- Principal Investigator
  
  TSUBOYAMA Tadao, 琴浦良彦
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  KYOTO UNIVERSITY

All 2015 2014 2013 2012 2011 2007 2006 2005

All Journal Article Presentation

[Journal Article] 誌説：変形性膝関節症のX線像と痛み：解離はなぜ生じるのか2015
- Author(s)
  赤木將男
- Journal Title
  
  臨床リウマチ
  
  Volume : 27 Pages : 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462389
[Journal Article] Inhibition of ASCT2 is essential in all-trans retinoic acid-induced reduction of adipogenesis in 3T3-L1 cells.2015
- Author(s)
  K. Takahashi, N. Uchida, C. Kitanaka, C. Sagara, M. Imai, and N. Takahashi,
- Journal Title
  
  FEBS Open Bio.
  
  Volume : 5 Pages : 571-578
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07950, KAKENHI-PROJECT-25462389
[Journal Article] 強制走行負荷による非侵襲性マウス変形性膝関節症モデルの作成2012
- Author(s)
  橋本和彦赤木將男
- Journal Title
  
  近畿大学医学会雑誌
  
  Volume : 37巻第1・2号 Pages : 11-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591694
[Journal Article] 強制走行負荷による非侵襲性マウス変形性膝関節症モデルの作成2012
- Author(s)
  橋本和彦、赤木將男
- Journal Title
  
  近畿大学医学雑誌　37：11-20, 2012
  
  Volume : 37 Pages : 11-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591694
[Journal Article] Possible Involvement of Oxidized Low-density Lipoprotein with Lectin-like Oxidized Low-density Lipoprotein Receptor 1 in Pathogenesis and Progression of Human Osteorthritis2007
- Author(s)
  Masao Akagi, et. al.
- Journal Title
  
  Osteoarthritis and Cartilage 15(3)
  
  Pages : 281-290
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Possible Involvement of Oxidized Low-density Lipoprotein with.Lectin-like Oxidized Low-density Lipoprotein Receptor 1 in Pathogenesis and Progression of Human Osteoarthritis2007
- Author(s)
  Masao Akagi
- Journal Title
  
  Osteoarthritis and Cartilage 15(3)
  
  Pages : 281-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Possible Involvement of Oxidized Low-density Lipoprotein with Lectin-like Oxidized Low-density Lipoprotein Receptor 1 in Pathogenesis and Progression of Human Osteoarthritis.2007
- Author(s)
  Masao Akagi, Soya Kanata, Shigeshi Mori, Hiroyuki Itabe, Tatsuya Sawamura, Chiaki Hamanishi
- Journal Title
  
  Osteoarthritis and Cartilage 15(3)
  
  Pages : 281-290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Cyclic Tensile Stretch Load and Oxidized Low Density Lipoprotein Synergistically Induce Lectin-like Oxidized LDL Receptor-1 in Cultured Bovine Chondrocytes,Resulting in Decreased Cell Viability and Glycosaminoglycan Synthesis2006
- Author(s)
  Masao Akagi
- Journal Title
  
  J Orthop.Res 24(8)
  
  Pages : 1782-1790
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Cyclic Tensile Stretch Load and Oxidized Low Density Lipoprotein Synergistically Induce Lectin-like Oxidized LDL Receptor-1 in Cultured Bovine Chondrocytes, Resulting in Decreased Cell Viability and Glycosaminoglycan Synthesis.2006
- Author(s)
  Masao Akagi, et al.
- Journal Title
  
  J Orthop. Res, 24(8)
  
  Pages : 1782-1790
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Cyclic Tensile Stretch Load and Oxidized Low Density Lipoprotein Synergistically Induce Lectin-like Oxidized LDL Receptor-1 in Cultured Bovine Chondrocytes, Resulting in Decreased Cell Viability and Glycosaminoglycan Synthesis.2006
- Author(s)
  Masao Akagi, Shunji Nishimura, Kohji Yoshida, Takumi Kakinuma, Tatsuya Sawamura, Hiroshi Munakata, Chiaki Hamanishi.
- Journal Title
  
  J Orthop. Res 24(8)
  
  Pages : 1782-1790
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Oxidized LDL binding to LOX-1 upregulates VEGF expression in cultured bovine chondrocytes through activation of PPAR-γ.2006
- Author(s)
  Sohya Kanata, Masao Akagi, Shunji Nishimura, Sumio Hayakawa, Kohji Yoshida, Tatsuya Sawamura, Hiroshi Munakata, Chiaki Hamanishi
- Journal Title
  
  Biochem Biophy Res Comm 348(3)
  
  Pages : 1003-1010
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Journal Article] Effects of Hyperlipidemia on Progression of Knee Osteoarthritis2005
- Author(s)
  Akio Nishimura, Masao Akagi, Chiaki Hamanishi
- Journal Title
  
  Med J of Kinki University 30(3,4)
  
  Pages : 93-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Presentation] アンジオテンシンⅡはメカニカルストレスによる変形性関節症を促進させる2015
- Author(s)
  山岸孝太郎　墳本一郎　橋本和彦　赤木將男
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場(富山市)
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-25462389
[Presentation] 高血圧によるOA変化：つくば高血圧モデルマウスを用いた検討2014
- Author(s)
  山岸孝太郎、墳本一郎、井上紳司、橋本和彦、赤木將男
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25462389
[Presentation] 軟骨細胞肥大分化過程におけるlocal RASと酸化ストレス2014
- Author(s)
  中村文久、墳本一郎、井上紳司、赤木將男
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25462389
[Presentation] Zymosan誘発性関節炎モデルマウスにおけるLOX-1の滑膜炎と軟骨変性に対する関与の検討2013
- Author(s)
  小田豊、赤木將男、橋本和彦、浜西千秋
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2013-03-01
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 異なる野生型マウスでの強制走行負荷による変形性膝関節症様変化の比較検討2013
- Author(s)
  橋本和彦赤木將男小田豊浜西千秋
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 異なる野生型マウスでの強制走行負荷による変形性膝関節症様変化の比較検討2013
- Author(s)
  橋本和彦、赤木將男、小田豊、濵西千秋
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] Zymosan誘発性関節炎モデルマウスにおけるLOX-1の滑膜炎と軟骨変性に対する関与の検討2013
- Author(s)
  小田豊、赤木將男、橋本和彦、濵西千秋
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 強制走行負荷によるマウス変形性膝関節症モデルの検討2012
- Author(s)
  橋本和彦赤木將男岸本英樹浜西千秋寺村岳士小野寺勇太
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-09
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] CHARACTERISING NON-SURGICAL MURINE KNEE OSTEOARTHRITIS MODEL PRODUCED BY CONTROLLED FORCED RUNNING2012
- Author(s)
  Hashimoto K, Akagi M
- Organizer
  2012 OARSI World Congress
- Place of Presentation
  Barcelona Spain
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 強制走行負荷によるマウス変形性膝関節症モデルの作成2012
- Author(s)
  橋本和彦、赤木將男、濵西千秋
- Organizer
  第3回　ヒアルロン酸研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] CHARACTERISING NON-SURGICAL MURINE KNEE OSTEOARTHRITIS MODEL PRODUCED BY CONTROLLED FORCED RUNNING2012
- Author(s)
  Hashimoto K, Akagi M
- Organizer
  2012 Osteoarthritis Research Society International (OARSI) World Congress
- Place of Presentation
  スペイン（バルセロナ）
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 強制走行負荷によるマウス変形性膝関節症モデルの検討2012
- Author(s)
  赤木將男
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋(ウィル愛知)
- Year and Date
  2012-03-09
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 非侵襲性OAモデルマウスと侵襲性OAモデルマウスの比較検討2011
- Author(s)
  赤木將男
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋(ベイシア文化ホール)
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 走行負荷でのマウス膝関節変形の検討2011
- Author(s)
  赤木將男
- Organizer
  第39回日本関節病学会
- Place of Presentation
  横浜(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 走行負荷でのマウス膝関節変形の検討2011
- Author(s)
  橋本和彦赤木將男岸本英樹浜西千秋寺村岳士小野寺勇太
- Organizer
  第39回日本関節病学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 走行負荷でのマウス膝関節変形の検討2011
- Author(s)
  赤木將男
- Organizer
  第24回日本軟骨代謝学会
- Place of Presentation
  福岡(ポスター発表)
- Year and Date
  2011-03-04
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 非侵襲性OAモデルマウスと侵襲性OAモデルマウスの比較検討2011
- Author(s)
  橋本和彦赤木將男岸本英樹浜西千秋寺村岳士小野寺勇太
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] 走行負荷でのマウス膝関節変形の検討(ポスター発表)2011
- Author(s)
  橋本和彦赤木將男岸本英樹浜西千秋
- Organizer
  第24回日本軟骨代謝学会
- Place of Presentation
  福岡
- Year and Date
  2011-03-04
- Data Source
  KAKENHI-PROJECT-22591694
[Presentation] Oxidized low-density lipoprotein binding to lectin-like oxidized lipoprotein receptor-1(LOX-1) upregulates Vascular endothelial growth factor expression in cultured bovine articular chondrocytes through PPAR-gamma activation2007
- Author(s)
  Sohya Kanata, Masao Akagi, Shunji Nishimura, Akio Nishimura, Shigeki Asada, Shigeshi Mori, Chiaki Hamanishi
- Organizer
  53nd Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Diego, CA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Presentation] Oxidized-LDL binding to Lectin-like ox-LDL receptor 1(LOX-1) in bovine cultured chondrocytes increases VEGF expression through activation of PPAR-gamma.2006
- Author(s)
  Sohya Kanata, Masao Akagi, Akio Nishimura, Shigeshi Mori, Shigeki Asada, Chiaki Hamanishi
- Organizer
  19th Annual Meeting of the Japanese Society of Cartilage Metabolism
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Presentation] The effects of hyperlipidemic loading on cartilage degeneration in the knee : Experimental studies using a congenital hyperlipidemic rabbit(KHC rabbit)2006
- Author(s)
  Akio Nishimura, Masao Akagi, Sohya Kanata Shigeshi Mori, Shigeki Asada, Chiaki Hamanishi
- Organizer
  19th Annual Meeting of the Japanese Society of Cartilage Metabolism
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Presentation] Presence of oxidized low density lipoprotein(ox-LDL) with lectin-like oxidized lipoprotein receptor-1(LOX-1) correlates to degeneration of human osteoarthritic cartilage.2005
- Author(s)
  Masao Akagi, Muneya Kanata, Akio Nishimura, Shigeshi Mori, Shunji Nishimura, Chiaki Hamanishi.
- Organizer
  10th World Congress of Osteoarthritis Research Society International
- Place of Presentation
  Boston, MA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591602
[Presentation] PRESENCE OF OXIDIZED LOW DENSITY LIPOPROTEIN(OX-LDL)WITH LECTIN-LIKE OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR-1(LOX-1)CORRELATES TO DEGENERATION OF HUMAN OSTEOARTHRITIC CARTILAGE2005
- Author(s)
  Masao Akagi, et. al.
- Organizer
  10th World Congress of Osteoarthritis Research Society International
- Place of Presentation
  Boston,Massachusetts,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591602

1. ASADA Shigeki (00330283)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
2. 柿木良介 (20314198)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. HASHIMOTO Kazuhiko (10635569)

# of Collaborated Projects : 1results

# of Collaborated Products : 13results
4. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. TERAMURA Takeshi (40460901)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
6. TSUBOYAMA Tadao (90261221)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. HIRAOKA Masahiro (70173218)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. SOEN S (10142598)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. FUKUDA K (50201744)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. NONAKA T (70268407)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. OH M (20319734)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 井上紳司 (10642879)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 墳本一郎 (20770051)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 松田秀一 (40294938)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. 太田壮一 (70592484)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. 琴浦良彦 (50127081)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 岡正典 (20088537)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 原文彦 (30340798)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 森成志 (80351584)

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
20. 西村俊司 (80388545)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. 高橋勝彦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
22. 内田隆史

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

AKAGI Masao 赤木 将男

Research Projects

Research Products

Co-Researchers

Artificial nerves containing allogenic basal lamellae scaffold and bone marrow derived stem cellsOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

局所的レニン・アンギオテンシン系（RAS）活性化による関節軟骨変性の機序の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨髄間葉系幹細胞移植した同種脱細胞化神経片含有血管柄入りチューブ内での神経再生Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of local Renin-angiotensin system on development and progression of knee osteoarthritis(OA)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of the oxidized low-density lipoprotein/lectin-like oxidized low-density lipoprotein receptor-1 system to joint cartilage degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of Hyperlipidemia on Progression of Knee OsteoarthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of hyaluronan depolymerization due to Reactive oxygen species (ROS) produced by synoviocytes cultured in hypoxia, resulting synovial proliferation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Differential Display法による軟骨発生分化制御因子のクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new strategy of hyperthermia for metastatic bone tumor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 誌説：変形性膝関節症のX線像と痛み：解離はなぜ生じるのか2015

Author(s)

Journal Title

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[Journal Article] Inhibition of ASCT2 is essential in all-trans retinoic acid-induced reduction of adipogenesis in 3T3-L1 cells.2015

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[Journal Article] 強制走行負荷による非侵襲性マウス変形性膝関節症モデルの作成2012

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[Journal Article] 強制走行負荷による非侵襲性マウス変形性膝関節症モデルの作成2012

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[Journal Article] Possible Involvement of Oxidized Low-density Lipoprotein with Lectin-like Oxidized Low-density Lipoprotein Receptor 1 in Pathogenesis and Progression of Human Osteorthritis2007

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[Journal Article] Possible Involvement of Oxidized Low-density Lipoprotein with.Lectin-like Oxidized Low-density Lipoprotein Receptor 1 in Pathogenesis and Progression of Human Osteoarthritis2007

AKAGI Masao 赤木将男