MIHARA Kiyoshi 三原潔

… Alternative Names

三原潔ミハラキヨシ

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Researcher Number	00281444
Other IDs
Affiliation (Current)	2025: 武蔵野大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2007: Musashino University, Clinical Pharmaceutics, Associate Professor 2006: 武蔵野大学, 薬学研究所, 助教授 2004 – 2005: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Medical pharmacy
Keywords	Principal Investigator immunosuppressive drugs / 薬物動態・薬力学解析 / 拒絶反応 / バイオマーカー / 免疫抑制剤 / 臓器移植 / Non-invasive / Pharmacodynamics / Pharmacokinetics / Protein Chip … More / Rejection / Biomarkers / Organ Transplantation / 低浸襲 / プロテインチップ / PD analysis / PK / rejection / rat / cDNA microarray / biomarkers / organ transplantation / ラット / cDNAマイクロアレイ Less

Individualization of dosage for immunosuppressive drugs based on new biomarkersPrincipal Investigator
- Principal Investigator
  
  MIHARA Kiyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Musashino University
New biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in organ transplantationPrincipal Investigator
- Principal Investigator
  
  MIHARA Kiyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University

All 2008 2007 2006 2005

All Journal Article Presentation Patent

[Journal Article] Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole2008
- Author(s)
  Mihara A, Tanigawara Y, et. al.
- Journal Title
  
  Eur J Clin Pharlnacol 64
  
  Pages: 89-91
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole.2008
- Author(s)
  Mihara A, Tanigawara Y, et. al.
- Journal Title
  
  Eur J Chin Pharmacol. 64
  
  Pages: 89-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole.2008
- Author(s)
  Mihara A, Tanigawara Y, et. al.
- Journal Title
  
  Eur J Clin Pharmacol. 64(1)
  
  Pages: 89-91
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] バイオマーカーによる診断と治療効果の予測2007
- Author(s)
  三原潔
- Journal Title
  
  薬剤学:生命とくすり 67
  
  Pages: 188-192
- NAID
  10019492783
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias2006
- Author(s)
  Ogawa R, Kishi R, Mihara K, et al.
- Journal Title
  
  J. Clin. Pharmacol. 46・1
  
  Pages: 59-68
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590121
[Journal Article] Enantioselective and highly sensitive determination of carvedilol in human plasma and whole blood after administration of the racemate using normal-phase high-performance liquid chromatography.2006
- Author(s)
  Saito M, Mihara K, et al.
- Journal Title
  
  J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 843・1
  
  Pages: 73-77
- NAID
  10025788129
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias2006
- Author(s)
  Ogawa R, Kishi R, Mihara K, et al.
- Journal Title
  
  J.Clin.Pharmacol. 46(1)
  
  Pages: 59-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590121
[Journal Article] Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias2006
- Author(s)
  Ogawa R, Kishi R, Mihara K, et al.
- Journal Title
  
  J.Clin.Pharmacol. 46・1
  
  Pages: 59-68
- Data Source
  KAKENHI-PROJECT-16590121
[Journal Article] Enantioselective and highly sensitive determination of carvedilol in human plasma and whole blood after administration of the racemate using normal-phase high-performance liquid chromatography2006
- Author(s)
  Saito M, Mihara K, et. al.
- Journal Title
  
  J.Chromatogr.B Analyt.Technol.Biomed.Life Sci 843
  
  Pages: 73-77
- NAID
  10025788129
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Population Pharmacolinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias.2006
- Author(s)
  Ogawa R, Mihara K, et. al.
- Journal Title
  
  J Clin Pharmacol. 46(10
  
  Pages: 59-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Enantioselective and highly sensitive determination of the racemate using using normal-phase high-performance liquid chromatography.2006
- Author(s)
  Saito M, Mihara K, et. al.
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci. 843(1)
  
  Pages: 73-77
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590155
[Journal Article] Evaluation of Bayesian Estimation of Pharmacokinetic Parameters2005
- Author(s)
  Tsuchiwata S, Mihara K, et al.
- Journal Title
  
  Ther.Drug Monit. 27・1
  
  Pages: 18-24
- Data Source
  KAKENHI-PROJECT-16590121
[Journal Article] Evaluation of Bayesian Estimation of Pharmacokinetic Parameters2005
- Author(s)
  Tsuchiwata S, Mihara K, et al.
- Journal Title
  
  Ther.Drug Monit. 27(1)
  
  Pages: 18-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590121
[Journal Article] Evaluation of Bayesian Estimation of Pharmacokinetic Parameters2005
- Author(s)
  Tsuchiwata S, Mihara K, et al.
- Journal Title
  
  Ther. Drug Monit. 27・1
  
  Pages: 18-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590121
[Patent] 遺伝子マーカー及びその利用2006
- Inventor(s)
  谷川原祐介, 三原潔, 他
- Industrial Property Rights Holder
  学校法人慶應義塾大学
- Filing Date
  2006-01-13
- Data Source
  KAKENHI-PROJECT-16590121
[Patent] 遺伝子マーカー及びその利用2006
- Inventor(s)
  谷川原祐介, 三原潔, 他
- Industrial Property Rights Holder
  慶應義塾
- Filing Date
  2006-01-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590121
[Patent] 遺伝子マーカー及びその利用2005
- Inventor(s)
  谷川原祐介, 三原潔, 他
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Number
  2005-006728
- Filing Date
  2005-01-13
- Data Source
  KAKENHI-PROJECT-16590121
[Patent] 遺伝子マーカー及びその利用2005
- Inventor(s)
  谷川原祐介, 三原潔, 他
- Industrial Property Rights Holder
  学校法人慶應義塾
- Filing Date
  2005-05-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590121
[Patent] 遺伝子マーカー及びその利用2005
- Inventor(s)
  谷川原祐介, 三原潔, 他
- Industrial Property Rights Holder
  学校法人慶應義塾大学
- Filing Date
  2005-05-30
- Data Source
  KAKENHI-PROJECT-16590121
[Patent] 遺伝子マーカー及びその利用2005
- Inventor(s)
  谷川原祐介, 三原潔, 他
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Number
  2005-006727
- Filing Date
  2005-01-13
- Data Source
  KAKENHI-PROJECT-16590121
[Presentation] 抗原提示細胞指向型キャリアを用いたNFκBデコイ送達に基づくラット心移植急性拒絶におけるサイトカイン産生抑制2007
- Author(s)
  樋口ゆり子、三原潔, ら
- Organizer
  日本薬剤学会第22年会
- Place of Presentation
  さいたま市
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-18590155
[Presentation] New biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in organ transplantation.2006
- Author(s)
  Mihara K, iketani O, Tanigawara Y
- Organizer
  The 3rd Korea-Japan Joint Symposium on Drug Delivery and Therapy
- Place of Presentation
  Seoul.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590155
[Presentation] Expression of AIF1, a gene marker for rejection, in peripheral blood in rat transplantation model and living-donor Liver transplantation.2006
- Author(s)
  Ishikawa H, Mihara K, Tanigawara Y, et. al.
- Organizer
  The 23rd Annual Meeting of The Japanese Society of Therapeutic Drug Monitoring
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590155
[Presentation] New biomarkers for acute rejection and therapeutic effect of immunosu ppressive drugs in organ transplantation2006
- Author(s)
  Mihara K, Iketani O, Tanigawara Y
- Organizer
  The 3rd Korea-Japan Joint Symposium on Drug Delivery and Therapy
- Place of Presentation
  韓国、ソウル
- Year and Date
  2006-04-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590155

1. TANIGAWARA Yusuke (30179832)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. TANABE Minoru (50197513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIHARA Kiyoshi 三原 潔

三原 潔 ミハラ キヨシ

Research Projects

Research Products

Co-Researchers

Individualization of dosage for immunosuppressive drugs based on new biomarkersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in organ transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole.2008

Author(s)

Journal Title

Data Source

[Journal Article] Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole.2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] バイオマーカーによる診断と治療効果の予測2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enantioselective and highly sensitive determination of carvedilol in human plasma and whole blood after administration of the racemate using normal-phase high-performance liquid chromatography.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias2006

Author(s)

Journal Title

Data Source

[Journal Article] Enantioselective and highly sensitive determination of carvedilol in human plasma and whole blood after administration of the racemate using normal-phase high-performance liquid chromatography2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Population Pharmacolinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enantioselective and highly sensitive determination of the racemate using using normal-phase high-performance liquid chromatography.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Evaluation of Bayesian Estimation of Pharmacokinetic Parameters2005

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of Bayesian Estimation of Pharmacokinetic Parameters2005

Author(s)

Journal Title

Description

Data Source

MIHARA Kiyoshi 三原潔

三原潔ミハラキヨシ