NOJIMA Takahiko 野島高彦

Researcher Number	00291930
Other IDs
Affiliation *help	2014 – 2018 : 北里大学, 一般教育部, 准教授 2009 – 2013 : Kitasato University, 一般教育部, 講師 2010 : 北里大学, 一般教育部自然科学教育センター 2007 – 2009 : 東京大学, 生産技術研究所, 助教 2006 : 九州大学, 工学研究科, 助手 … More
Review Section/Research Field	Principal Investigator Chemistry related to living body Except Principal Investigator Science and Engineering / 生物・生体工学 / Chemistry related to living body / Bioorganic chemistry / Bioinformatics/Life informatics / Nanomaterials/Nanobioscience / 工業分析化学
Keywords	Principal Investigator DNA / 論理ゲート / PCR / プライマー / プロテオミクス / GFP / 蛋白質 / 翻訳 / マスキング / 生体分子間相互作用 … More Except Principal Investigator カリウムイオン / インターカレータ / テロメアDNA / intercalator / telomere DNA / ピレン / テロメアDNA配列 / SNP / 蛍光共鳴エネルギー移動 / マイクロ・ナノデバイス / 蛍光共鳴エネルギー移動(FRET) / DNA / MEMS / tetraplex / sensing / 生化学 / threading intercalation / 1分子操作 / 水素結合 / 大環状インターカレータ / テロメラーゼ / Pyrene excimer / カリウムインジケーター / 縫い込み型 / 擬ポリフェロセンアレイ / molecular probe / thrombin-binding aptamer (TBA) / gene detection / 遺伝子多型 / extracellular potassium ion / DNA chip / センシング / 光電流 / 情報伝達 / 1分子計測 / 蛍光 / 表面張力 / テロメア / 解析プローブ / naphthalene diimide / ハイブリダイゼーション / オリゴヌクレオチド / Oxytricha / π-スタック / 一塩基多型(SNP) / マイクロマシン / カリウムセンシングオリゴヌクレオチド(PSO) / 高精度セルフアセンブリ / 分子スイッチ / 蛍光イメージング / ナノバイオ / 遺伝子検出 / エキシマー / DNAチップ / 動的制御 / システムオンチップ / 分子操作 / ナフタレンジミド / フェロセン / 環状インターカレータ / 1分子・ナノ計測 / Guanine quartet構造 / タンパク質合成 / トロンビンアプタマー / フェロセン化ナフタレンジイミド / 1分子イメージング / ピレンエキシマー / ruthenium complex / cyclic intercalator / 1分子科学 / ナトリウム / μ-TAS / アントラキノン / カリウム / 強相関構造 / 混合 / DNAコンピュータ / ゲノムプロジェクト / ルシフェラーゼ / ナノ界面・表面 / fluorescence resonance energy transfer (FRET) / TAMRA / 細胞間カリウムイオン / 蛍光励起共鳴エネルギー移動 / electrochemical measurement / NEMS / ナノバイオロジー / 自己組織化 / FRET / マイクロファブリケーション / テトラキスアクリジニルペプチド(TAP) / 四本鎖DNA構造 / センシング材料 / 四本鎖 / ナノ計測 / telomerase / ferrocene / 4本鎖 / photocurrent / 融解温度 / ミスマッチ塩基 / ナフタレンジイミド / 電気インピーダンス測定 / ナノ流体デバイス / エキシマー発光 / FAM / Potassium Sensing Oligonucleotide(PSO) / DNAワイヤ / ナノサイズ / β-ジクロデキストリン / ヘテロ二重らせん / 酵素反応 / 電気化学的検出 / 神経細胞 / 分子プローブ / 流体 / 味蕾細胞 / tetrakis-acridiny peptide / oligonucelotide / X線構造解析 / マイクロ化学システム / potassium ion / ルテニウム錯体 / human genome Less

Construction of a logic gate system based on precision molecular recognition of DNAPrincipal Investigator
- Principal Investigator
  
  NOJIMA Takahiko
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kitasato University
Development of Molecular Sorter using Nanofluidic Device
- Principal Investigator
  
  YAMAMOTO Takatoki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  The University of Tokyo
On-chip cell-free genetic engineering as a research technology for proteomicsPrincipal Investigator
- Principal Investigator
  
  NOJIMA Takahiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo
Mechanism of High-Precision Molecular Computing and its Evaluation
- Principal Investigator
  
  MURATA Satoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Tokyo Institute of Technology
カリウムイオンのインサイチューイメージング試薬の開発
- Principal Investigator
  
  TAKENAKA Shigeori
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyushu Institute of Technology
プロテオミクス基盤技術としてのリガンド-情報分子コンジュゲート創製Principal Investigator
- Principal Investigator
  
  野島高彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo
  Kyushu University
Fluorometric sensing of potassium ion by using telomere DNA and its application for cell imaging
- Principal Investigator
  
  TAKENAKA Shigeori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyusyu Institute of Technology
  Kyushu University
A novel detection system based on amplification and a strongly correlated hydrogen network
- Principal Investigator
  
  TAKENAKA Shigeori
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyushu University
Cyclic ferrocenyl intercalator as a novel probe for gene polymorphism analysis
- Principal Investigator
  
  TAKENAKA Shigeori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyushu University
Gene Detection by Light-to-electric Converting Intercalator and Its Application to DNA
- Principal Investigator
  
  TAKAGI Makoto
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  工業分析化学
- Research Institution
  Kyushu University
マイクロ生化学反応システムの開発研究
- Principal Investigator
  
  FUJII Teruo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  生物・生体工学
- Research Institution
  The Institute of Physical and Chemical Research

All 2015 2012 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Application of cell-free expression of GFP for evaluation of microsystems2012
- Author(s)
  T.Nojima, S.Kaneda, H.Kimura, T.Yamamoto, T.Fujii
- Journal Title
  
  Frontiers in Bioscience
  
  Volume : 17 Pages : 1931-1939
- DOI
  10.2741/4029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710120, KAKENHI-PROJECT-23550197
[Journal Article] Detection of cRNA hybridized on a DNA chip using tetrakis-acridinyl peptide (TAP) cassette, consisting of TAP and partial self-complementary oligonucleotide, d[A18(TA)5]2007
- Author(s)
  K.Kawaai et al.
- Journal Title
  
  Analytical Sciences 23
  
  Pages : 267-270
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Direct modification of mRNA by ferrocenylcarbodiimide and its application for electrochemical detection of mRNA2007
- Author(s)
  K.Mukumoto et al.
- Journal Title
  
  Analytical Sciences 23
  
  Pages : 115-119
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Fluorescence energy transfer probes based on the guanine quadruplex formation for the fluorometric detection of potassium ion2006
- Author(s)
  S.Nagatoishi et al.
- Journal Title
  
  Analytica Chimica Acta 581
  
  Pages : 125-131
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Tetrakis-acridinyl peptide : Distance dependence of photoinduced electron transfer in DNA duplex2006
- Author(s)
  K.Mizuki et al.
- Journal Title
  
  Analytica Chimica Acta 578
  
  Pages : 88-92
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Ferrocenylnaphthalene diimide-based electrochemical detection of methylated gene2006
- Author(s)
  S.Sato et al.
- Journal Title
  
  Analytica Chimica Acta 578
  
  Pages : 82-87
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] G quadruplex-based FRET probes with the thrombin-binding aptamer (TBA) sequence designed for the efficient fluorometric detection of potassium ion2006
- Author(s)
  S.Nagatoishi et al.
- Journal Title
  
  ChemBioChem 7
  
  Pages : 1730-1737
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Immobilization of RNase S-peptide on a single-stranded DNA-fixed gold surface and effective masking of its surface by an acridinyl poly(ethvlene glycol)2006
- Author(s)
  K.Ohtsuka et al.
- Journal Title
  
  Analyst 131
  
  Pages : 55-61
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] A Pyrene-labeled G-quadruplex oligonucleotide as a fluorescence probe for potassium ions detection in biological applications2005
- Author(s)
  S.Nagatoishi et al.
- Journal Title
  
  Angewandte Chemie International Edition 44
  
  Pages : 449-454
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Pyrene-labeled. G-quadruplex Oligonucleotide as a Fluorescence Probe for Potassium Ions Detection in Biological Applications2005
- Author(s)
  Satoru Nagatoishi, Takahiko Nojima, Bernard Juskowiak, Shigeori Takenaka
- Journal Title
  
  Angew.Chem.Int.Ed. 44
  
  Pages : 5067-5070
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350089
[Journal Article] Synthesis of ferrocenylcarbodiimide as a convenient electrochemically active labeling reagent for nucleic acids2005
- Author(s)
  K.Mukumoto et al.
- Journal Title
  
  Tetrahedron 49
  
  Pages : 11705-11715
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Complexation of thrombin-binding aptamer oligonucleotide carrying fluorescence resonance energy transfer (FRET) dyes at both termini with potassium ion2005
- Author(s)
  Satoru Nagatoishi, Takahiko Nojima, Shigeori Takenaka
- Journal Title
  
  Nucleic Acids Symposium Series 49
  
  Pages : 233-234
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16350089
[Journal Article] Genotyping of human lipoprotein lipase gene by using ferrocenylnaphthalene diimide-based electrochemical hybridization assay (FND-EHA)2005
- Author(s)
  T.Nojima et al.
- Journal Title
  
  Analytical Sciences 21
  
  Pages : 1437-1441
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Determination of termination efficiency of transcription terminator using different fluorescent profile in green fluorescent protein mutants2005
- Author(s)
  T.Nojima et al.
- Journal Title
  
  Analytical Sciences 21
  
  Pages : 1479-1481
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Electrochemical telomerase assay with ferrocenylnaphthalene diimide as a tetraplex DNA-specific binder2005
- Author(s)
  S.Sato et al.
- Journal Title
  
  Analytical Chemistry 77
  
  Pages : 7304-7309
- Data Source
  KAKENHI-PROJECT-17750165
[Journal Article] Pyrene-labeled G-quadruplex Oligonucleotide as a Fluorescence Probe for Potassium Ions Detection in Biological Applications2005
- Author(s)
  Satoru Nagatoishi, Takahiko Nojima, Bernard Juskowiak, Shigeori Takenaka
- Journal Title
  
  Angew.Chem.Int.Ed. 44
  
  Pages : 5067-5070
- Data Source
  KAKENHI-PROJECT-16350089
[Journal Article] Pyrene-labeled G-quadruplex Oligonucleotide as a Fluorescence Probe for Potassium lons Detection in Biological Applications2005
- Author(s)
  Satoru Nagatoishi, Takahiko Nojima, Bernard Juskowiak, Shigeori Takenaka
- Journal Title
  
  Angew.Chem.Int.Ed 44
  
  Pages : 5067-5070
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16350089
[Journal Article] DNA四本鎖構造を利用したカリウムイオンの検出2004
- Author(s)
  野島高彦, 竹中繁織
- Journal Title
  
  機能材料 24
  
  Pages : 5-9
- Data Source
  KAKENHI-PROJECT-16350089
[Presentation] Construction of a molecular logic gate inspired by polymerase chain reaction2015
- Author(s)
  Takahiko Nojima
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015)
- Place of Presentation
  ハワイ(アメリカ合衆国)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23550197
[Presentation] 蛍光蛋白質の生体外発現を演算レポーターに用いるDNAロジックゲート2012
- Author(s)
  野島高彦，山本貴富喜，木村啓志，藤井輝夫
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川)
- Data Source
  KAKENHI-PROJECT-23550197

1. TAKENAKA Shigeori (60188208)

# of Collaborated Projects : 5results

# of Collaborated Products : 5results
2. FUJII Teruo (30251474)

# of Collaborated Projects : 4results

# of Collaborated Products : 2results
3. YAMAMOTO Takatoki (20322688)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
4. NAKAMURA Shigeo (00264078)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. MURATA Satoshi (10334533)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. FUJIMOTO Kenzo (90293894)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. FUKUBA Tatsuhiro (80401272)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. TAKAGI Makoto (90037739)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 細川和生

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. KIMURA Hiroshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

NOJIMA Takahiko 野島 高彦

Research Projects

Research Products

Co-Researchers

Construction of a logic gate system based on precision molecular recognition of DNAPrincipal Investigator

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On-chip cell-free genetic engineering as a research technology for proteomicsPrincipal Investigator

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プロテオミクス基盤技術としてのリガンド-情報分子コンジュゲート創製Principal Investigator

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[Journal Article] Application of cell-free expression of GFP for evaluation of microsystems2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of cRNA hybridized on a DNA chip using tetrakis-acridinyl peptide (TAP) cassette, consisting of TAP and partial self-complementary oligonucleotide, d[A18(TA)5]2007

Author(s)

Journal Title

Data Source

[Journal Article] Direct modification of mRNA by ferrocenylcarbodiimide and its application for electrochemical detection of mRNA2007

Author(s)

Journal Title

Data Source

[Journal Article] Fluorescence energy transfer probes based on the guanine quadruplex formation for the fluorometric detection of potassium ion2006

Author(s)

Journal Title

Data Source

[Journal Article] Tetrakis-acridinyl peptide : Distance dependence of photoinduced electron transfer in DNA duplex2006

NOJIMA Takahiko 野島高彦