• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Chiba Hideki  千葉 英樹

ORCIDConnect your ORCID iD *help
… Alternative Names

CHIBA Hideki  千葉 英樹

Less
Researcher Number 00295346
Other IDs
Affiliation (Current) 2025: 福島県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2017 – 2024: 福島県立医科大学, 医学部, 教授
2014 – 2015: 福島県立医科大学, 医学部, 教授
2011 – 2012: 福島県立医科大学, 医学部, 教授
2007 – 2009: Sapporo Medical University, School of Medicine, Associate Professor
2006: Sapporo Medical University, School of Medicine, Associate Professor, 医学部, 助教授
2000 – 2005: 札幌医科大学, 医学部, 講師
1998 – 1999: 札幌医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Experimental pathology / Experimental pathology / Human pathology / Basic Section 49030:Experimental pathology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Except Principal Investigator
Basic Section 49020:Human pathology-related / Experimental pathology / Obstetrics and gynecology / Obstetrics and gynecology / Experimental pathology … More / Human pathology / Tumor biology / Human pathology / Ophthalmology Less
Keywords
Principal Investigator
タイト結合 / 核内受容体 / クローディン / がん / 細胞接着 / HNF-4α / 血液組織関門 / 細胞間接着 / 細胞間接着装置 / 細胞極性 … More / 病理学 / ノックアウト細胞 / 遺伝子発現誘導 / Cre / F9 / レチノイド / 代謝 / 浸潤 / がん悪性形質 / がん増悪 / 腫瘍 / リン酸化 / 組織再生 / 皮膚損傷 / ニッチ / 脂肪由来幹細胞 / 間葉系幹細胞 / 幹細胞 / 細胞内シグナル / クロストーク / 子宮内膜癌 / 子宮体がん / 子宮体癌 / シグナル伝達 / エストロゲン受容体 / blood-tissue barrier / tight junction / junctional complex / cell proliferation / epithelial differentiation / epithelial polarization / nuclear receptor / プロテインキナーゼC / 細胞増殖 / 上皮分化 / Enodothelial cells / Protein kinase A / Cyclic AMP / MAP kinase / Blood-tissue barrier / Blood-brain barrier / Claudin / Tight junction / Tet-onシステム / 血管内皮細胞 / プロテインキナーゼA / サイクリックAMP / MAPキナーゼ / 血液脳関門 / 分化転換 / 再生医学 / C型肝炎 / トランスレーショナルリサーチ / C型肝炎ウィルス / 抗体医薬 / トうンスレーショナルリサーチ / 肝癌 / 感染症 / C 型肝炎ウィルス / 細胞・組織 / クローデイン / loxP / 遺伝子発現誘導システム / 部位特異的遺伝子組換え / リガンド誘導性Creリコンビナーゼ / lox P / 生体バリアー / 臓器内胚芽 / 上皮 … More
Except Principal Investigator
タイト結合 / occludin / claudin-5 / tight junction / claudin / クローディン / HNF-4α / Fas Ligand / insulin resistance / adiponectin / matrix metalloproteinase / vascular endothelial growth factor / Toll-like receptor / TSLP / ヒト鼻粘膜 / 病理学 / 鼻アレルギー / Ca吸収 / 糖尿病網膜症 / バリア機能 / 血管内皮細胞 / 腸管オルガノイド / ゲノム編集 / 腸上皮幹細胞 / 蠕動 / JAMファミリー / CLMP / 腸管幹細胞 / Ca absorption / diabetic retinopathv / glial cell / retinoic acid / human nasal mucosa / 上皮細胞極性 / フェンス機能 / シグナル伝達 / アポトーシス / オクルジン / グリア細胞 / レチノイン酸 / follicle atresia / polycystic ovary / androgen / HOMA / BMI / testosteorone / polysyctic ovary syndrome / MT1-MMP / caspase 8 / Fas / apoptosis / testosterone / polycystic ovary syndrome / 閉鎖卵胞 / 多嚢胞卵巣 / fa)ラット / Zucker (fa / FasLligand / 卵胞閉鎖 / 多嚢胞性卵巣 / インスリン抵抗性 / アンドロゲン / vascular permeability / ovarian hyperstimulation syndrome / corous Luteum / 血管新生 / 血管透過性 / 卵巣過剰刺激症候群 / 黄体 / gap junction / nuclear receptor / hepatocyte / enodothelial cells / PI3K / MAPK / ギャップ結合 / 核内レセプター型転写因子 / 肝細胞 / differentiation / smooth-msucle actin / osteoblast / pericyte / 分化機能 / 平滑筋アクチン / 骨芽細胞 / 血管周皮細胞 / ペリサイト / 予後因子 / 転移 / がん転移 / 細胞運動 / 浸潤 / 予後 / 乳癌 / S100A16 / S100A14 / ビタミンD受容体欠損マウス / Ca吸収機構 / 樹状細胞 / 生体機能利用 / 細胞・組織 / サイトカイン / 肝(黄疸) / 膵管上皮 / TER / 血液透過性 / neurturin / GDNF / 血液脳関門 / 血液網膜関門 / アクチン / Min mouse / 細胞電気抵抗 Less
  • Research Projects

    (20 results)
  • Research Products

    (131 results)
  • Co-Researchers

    (25 People)
  •  Novel mechanism of cancer progression by phosphorylation of nuclear receptorsPrincipal Investigator

    • Principal Investigator
      千葉 英樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Fukushima Medical University
  •  Tissue regeneration using the niche signal for stem cellsPrincipal Investigator

    • Principal Investigator
      Chiba Hideki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Fukushima Medical University
  •  Fate decision of intestinal stem cells by tight junction molecules

    • Principal Investigator
      Tanaka Mizuko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Fukushima Medical University
  •  Promotion of cancer progression by aberrant cell adhesion signalingPrincipal Investigator

    • Principal Investigator
      Chiba Hideki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Fukushima Medical University
  •  Development of a novel direct reprogramming method using cell adhesion signalPrincipal Investigator

    • Principal Investigator
      Chiba Hideki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Fukushima Medical University
  •  Analysis of molecular function of S100A14 and its clinical aplication to diagnosis and therapy of breast cancer.

    • Principal Investigator
      SUGINO Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Shizuoka Cancer Center Research Institute
  •  Development of a novel therapy targeting tight-junction protein occludin against hepatitis CPrincipal Investigator

    • Principal Investigator
      CHIBA Hideki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Fukushima Medical University
  •  Pathobiology of the tight junction : from cell biology of paracellular pathway to bed-side

    • Principal Investigator
      SAWADA Norimasa
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Regulation of biological barrier and cell polarity formationPrincipal Investigator

    • Principal Investigator
      CHIBA Hideki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Biological barrier and human diseases

    • Principal Investigator
      KOJIMA Takashi, 小山内 誠
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Molecular mechanism of formation and regulation of the biological barrierPrincipal Investigator

    • Principal Investigator
      CHIBA Hideki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Study for the etiology of polycystic ovary using a rat model

    • Principal Investigator
      ENDO Toshiaki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Sapporo Medical University
  •  Molecular pathophysiology of the biological barrier regulation of molecular passage through paracellular spaces.

    • Principal Investigator
      SAWADA Norimasa
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Reconstitution and regulation of the blood-tissue barrierPrincipal Investigator

    • Principal Investigator
      CHIBA Hideki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  The differences of mechanisms between normal luteal formation and occurrence of ovarian hyperstimulation syndrome

    • Principal Investigator
      ENDO Toshiaki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Sapporo Medical University
  •  遺伝子改変F9細胞株を用いた生体バリアの機能解析Principal Investigator

    • Principal Investigator
      千葉 英樹
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  糖尿病網膜症と血液網膜関門のタイト結合

    • Principal Investigator
      澤田 典均
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Sapporo Medical University
  •  Induction of pericyte differentiation in human osteoblastic cell line

    • Principal Investigator
      IKEDA Tatsuru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  血管内皮細胞のタイト結合蛋白と癌転移

    • Principal Investigator
      SAWADA Norimasa
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Sapporo Medical University
  •  生体バリアー関連分子の同定と機能解析に関する研究Principal Investigator

    • Principal Investigator
      千葉 英樹
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University

All 2023 2021 2020 2019 2018 2017 2015 2013 2012 2011 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Patent

  • [Journal Article] Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence2023

    • Author(s)
      Nishimagi Atsushi、Kobayashi Makoto、Sugimoto Kotaro、Kofunato Yasuhide、Sato Naoya、Haga Junichiro、Ishigame Teruhide、Kimura Takashi、Kenjo Akira、Kobayashi Yasuyuki、Hashimoto Yuko、Marubashi Shigeru、Chiba Hideki
    • Journal Title

      Clinical and Experimental Medicine

      Volume: 23 Issue: 8 Pages: 4985-4995

    • DOI

      10.1007/s10238-023-01098-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08896, KAKENHI-PROJECT-23K08716, KAKENHI-PROJECT-21K06950, KAKENHI-PROJECT-23K27394
  • [Journal Article] Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β2023

    • Author(s)
      Murakami-Nishimagi Yuko、Sugimoto Kotaro、Kobayashi Makoto、Tachibana Kazunoshin、Kojima Manabu、Okano Maiko、Hashimoto Yuko、Saji Shigehira、Ohtake Tohru、Chiba Hideki
    • Journal Title

      Breast Cancer Research

      Volume: 25 Issue: 1 Pages: 41-41

    • DOI

      10.1186/s13058-023-01646-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08716, KAKENHI-PROJECT-21K06950, KAKENHI-PROJECT-23K27394
  • [Journal Article] Soluble JAM-C Ectodomain Serves as the Niche for Adipose-Derived Stromal/Stem Cells2021

    • Author(s)
      Yamazaki Morio、Sugimoto Kotaro、Mabuchi Yo、Yamashita Rina、Ichikawa-Tomikawa Naoki、Kaneko Tetsuharu、Akazawa Chihiro、Hasegawa Hiroshi、Imura Tetsuya、Chiba Hideki
    • Journal Title

      Biomedicines

      Volume: 9 Issue: 3 Pages: 278-278

    • DOI

      10.3390/biomedicines9030278

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K01753, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-20K21529, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-19K16615
  • [Journal Article] Molecular organization, regulation and function of tricellular junctions2020

    • Author(s)
      Higashi Tomohito、Chiba Hideki
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Biomembranes

      Volume: 1862 Issue: 2 Pages: 183143-183143

    • DOI

      10.1016/j.bbamem.2019.183143

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08699, KAKENHI-PROJECT-18K06223
  • [Journal Article] Cell adhesion signals regulate the nuclear receptor activity2019

    • Author(s)
      Sugimoto Kotaro、Ichikawa-Tomikawa Naoki、Kashiwagi Korehito、Endo Chihiro、Tanaka Satoshi、Sawada Norimasa、Watabe Tetsuya、Higashi Tomohito、Chiba Hideki
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 49 Pages: 24600-24609

    • DOI

      10.1073/pnas.1913346116

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08699, KAKENHI-PROJECT-17K08766, KAKENHI-PROJECT-19K16615
  • [Journal Article] Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth2015

    • Author(s)
      Morhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP
    • Journal Title

      FASEB J

      Volume: 29 Issue: 1 Pages: 274-285

    • DOI

      10.1096/fj.14-261404

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670191
  • [Journal Article] The liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression2015

    • Author(s)
      Kaneko T, Kanno C, Ichikawa-Tomikawa N, Kashiwagi K, Yaginuma N, Ohkoshi C, Tanaka M, Sugino T, Imura T, Hasegawa H, Chiba H
    • Journal Title

      Oncotarget

      Volume: 6 Issue: 32 Pages: 33345-33357

    • DOI

      10.18632/oncotarget.5428

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670191
  • [Journal Article] Methionine aminopeptidase 2 as a potential therapeutic target for human non-small cell lung cancers2015

    • Author(s)
      Shimizu H, Yamagishi S, Chiba H, Ghazizadeh M
    • Journal Title

      Adv Clin Exp Med

      Volume: 25 Pages: 117-128

    • Data Source
      KAKENHI-PROJECT-26670191
  • [Journal Article] Expression and function of lysophosphatidic acid receptor 1 in bladder cancer2015

    • Author(s)
      Kataoka M, Ishibashi K, Kumagai S, Yanagida T, Aikawa K, Chiba H, Kojima Y
    • Journal Title

      J Urol

      Volume: 194 Issue: 1 Pages: 238-244

    • DOI

      10.1016/j.juro.2014.12.028

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670191
  • [Journal Article] Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion.2015

    • Author(s)
      Tanaka M, Ichikawa-Tomikawa N, Shishito N, Nishiura K, Miura T, Hozumi A, Chiba H, Yoshida S, Ohtake T, Sugino T
    • Journal Title

      BMC Cancer

      Volume: 15 Issue: 1 Pages: 53-53

    • DOI

      10.1186/s12885-015-1059-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24501318, KAKENHI-PROJECT-26670191
  • [Journal Article] Evidence of vitamin D and interferon-ss cross-talk in human osteoblasts with 1a ,25-dihydroxyvitamin D_3 and rosigliatazone synergistically osteoblast-mediated mineralization.2013

    • Author(s)
      Woeckel VJ, Bruedigam C, Koedam M, Chiba H, van der Eerden BC, van LeeuwenJP
    • Journal Title

      Gene

      Volume: 512 Pages: 438-443

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] 蛍光ダイレクトラベリングによる生細胞蛍光イメージング2012

    • Author(s)
      冨川(市川)直樹, 千葉英樹
    • Journal Title

      Surgery Frontier

      Volume: 19 Pages: 335-340

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] IFN ss impairs extracellular matrix formation leading to inhibition of mineralization by effects in the early stage of human osteoblast differentiation2012

    • Author(s)
      Woeckel VJ, Eijken M, van de Peppel J, Chiba H, van der Eerden BC, van LeeuwenJP
    • Journal Title

      J Cell Physiol

      Volume: 227 Pages: 2668-2676

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Stereotaxic injection の手法と応用2012

    • Author(s)
      冨川(市川)直樹, 千葉英樹
    • Journal Title

      Surgery Frontier

      Volume: 19 Pages: 445-450

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Evidence of vitamin D and interferon- ss cross-talk in human osteoblasts with 1a,25-dihydroxyvitamin D_3 being dominant over interferon-ss in stimulating mineralization2012

    • Author(s)
      Woeckel VJ, Eijken M, van de Peppel J, Chiba H, van der Eerden BC, van LeeuwenJP
    • Journal Title

      J Cell Physiol

      Volume: 227 Pages: 3258-3266

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] The transient potential channel TRPV6 is dynamically expressed in bone cells but in not crucial for bone mineralization in mice2012

    • Author(s)
      van der Eerden BC, Weissgerber P, Fratzl-Zelman N, Olausson J, Hoenderop JG,Schreuders-Koedam M, Eijken M, Roschger P, de Vries TJ, Chiba H, Klaushofer K, Flockerzi V, Bindels RJ, Freichel M, van Leeuwen JP
    • Journal Title

      J Cell Physiol

      Volume: 227 Pages: 1951-1959

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Laminin a1 is essential for mouse cerebellar development.2012

    • Author(s)
      Ichikawa-Tomikawa N, Ogawa J, Douet V, Xu Z, Kamikubo Y, Sakurai T, Kohsaka S, Chiba H, Hattori N, Yamada Y,Arikawa-Hirasawa E
    • Journal Title

      Matrix Biol

      Volume: 31 Pages: 17-28

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Claudin-4-targeted therapy using Clostridium Perfringensenterotoxin for prostate cancer2012

    • Author(s)
      Maeda T, Murata M, Chiba H, Takasawa A, Tanaka S, Kojima T, Masumori N, Tsukamoto T, Sawada N
    • Journal Title

      Prostate

      Volume: 72 Pages: 351-360

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Interphase cytogenetic analysis of lung adenocarcinomas with bronchioloalveolar pattern.2012

    • Author(s)
      Shimizu H, Sugino T, Chiba H.
    • Journal Title

      Fukushima J Med Sci.

      Volume: 58(1) Pages: 66-73

    • NAID

      130002153561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501318
  • [Journal Article] Opposing actions of rosiglitazone and resveratrol on mineralization in human vascular smooth muscle cells2011

    • Author(s)
      Bruedigam C, Eijken M, Koedam M, Chiba H, van Leeuwen JP
    • Journal Title

      J Mol Cell Cardiol

      Volume: 51 Pages: 862-871

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Possible involevement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation2011

    • Author(s)
      Ichikawa-Tomikawa N, Sugimoto K, Satohisa S, Nishiura K, Chiba H
    • Journal Title

      J Biomed Biotechnol

      Volume: 2011 Pages: 253048-253048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Possible involevement of tight junctions, extracellular matrix and nuclear receptors in epithelialdifferentiation2011

    • Author(s)
      Ichikawa-Tomikawa N, Sugimoto K, Satohisa S, Nishiura K, Chiba H
    • Journal Title

      J Biomed Biotechnol

      Volume: 2011 Pages: 253048-253048

    • Data Source
      KAKENHI-PROJECT-23659187
  • [Journal Article] Tight junction proteins and signal transduction pathways in hepatocytes.2009

    • Author(s)
      Kojima T, Murata M, Yamamoto T, Lan M, Imamura M, Son S, Takano K-i, Yamaguchi H, Ito T, Tanaka S, Chiba H, Hirata K, Sawada N
    • Journal Title

      Histol Histopathol 24

      Pages: 1463-1472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells.2009

    • Author(s)
      Son S, Kojima T, Decaens C, Yamaguchi H, Ito T, Imamura M, Murata M, Tanaka S, Chiba H, Hirata K, Sawada N
    • Journal Title

      Histochem Cell Biol 131

      Pages: 411-424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells2009

    • Author(s)
      Son S, Kojima T, Decaens C, Yamaguchi H, Ito T, Imamura M, Murata M, Tanaka S, Chiba H, Hirata K, Sawada N
    • Journal Title

      Histochem Cell Biol 131

      Pages: 411-424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Thymic stromal lymphopoietin enhances tight junction barrier function of human nasal epithelial cells.2009

    • Author(s)
      Kamekura R, Kojima T, Koizumi J, Ogasawara N, Kurose M, Go M, Harimaya A, Murata M, Tanaka S, Chiba H, Himi T, Sawada N
    • Journal Title

      Cell Tissue Res 338

      Pages: 283-293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba H, Osanai M, Murata M, Kojima T, Sawada N
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy2008

    • Author(s)
      Nishikiori N, Osanai M, Chiba H, Kojima T, Inatomi S, Ohguro H, Sawada N
    • Journal Title

      Clinical Ophthalmology 2

      Pages: 233-235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Evidence for multiple peroxisome proliferator-activated receptor gamma transcripts in bone : Fine-tuning by hormonal regulation and mRNA stability2008

    • Author(s)
      Bruedigam C, Koedam M, Chiba H, Eijken M, van Leeuwen JP
    • Journal Title

      FEBS Lett 582

      Pages: 1618-1624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Wnt signaling acts and is regulated in a human osteoblast differentiation dependent manner2008

    • Author(s)
      Eijken M, Meijer IM, Westbroek I, Koedam M, Chiba H, Uitterlinden AG, Pols HA, van Leeuwen JP
    • Journal Title

      J Cell Biochem 104

      Pages: 568-579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Transmembrane proteins of tight junctions2008

    • Author(s)
      Chiba H, et. al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro2008

    • Author(s)
      Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T, Kurose M, Koizumi J, Kamekura R, Murata M, Tanaka S, Chiba H, Himi T, Sawada N
    • Journal Title

      J Mol Histol 39

      Pages: 265-273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway2008

    • Author(s)
      Hatakeyama N, Kojima T, Iba K, Murata M, Thi MM, Spray DC, Osanai M, Chiba H, Ishii S, Yamashita T, Sawada N
    • Journal Title

      Cell Tissue Res 334

      Pages: 243-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma2008

    • Author(s)
      Satake S, Semba S, Matsuda Y, Usami Y, Chiba H, Sawada N, Kasuga M, Yokozaki H
    • Journal Title

      Pathol Int 58

      Pages: 156-163

    • NAID

      10027375982

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Tight junction proteins claudin-2 and-12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.2008

    • Author(s)
      Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, Uchiyama Y, Yamamoto Y, Wada T, Kojima T, Yokozaki H, Yamashita T, Kato S, Sawada N, Chiba H
    • Journal Title

      Mol Biol Cell 19

      Pages: 1912-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba H, et. al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba H, et. al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Transmembrane proteins of tight junctions2008

    • Author(s)
      Chiba H, Osanai M, Murata M, Kojima T, Sawada N
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba H, et. al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba, H, et. al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma.2008

    • Author(s)
      Satake S, Semba S, Matsuda Y, Usami Y, Chiba H, Sawada N, Kasuga M, Yokozaki H
    • Journal Title

      Pathol Int 58

      Pages: 156-163

    • NAID

      10027375982

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation2008

    • Author(s)
      Koizumi J, Kojima T, Ogasawara N, Kamekura R, Kurose M, Go M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      Mol Pharmacol 74

      Pages: 432-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro.2008

    • Author(s)
      Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T, Kurose M, Koizumi J, Kamekura R, Murata M, Tanaka S, Chiba H, Himi T, Sawada N
    • Journal Title

      J Mol Histol 39

      Pages: 265-273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba H, et al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Transmembrane proteins of tight junctions.2008

    • Author(s)
      Chiba H, et al.
    • Journal Title

      BBA-Biomembranes 1778

      Pages: 588-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway.2008

    • Author(s)
      Hatakeyama N, Kojima T, Iba K, Murata M, Thi MM, Spray DC, Osanai M, Chiba H, Ishii S, Yamashita T, Sawada N
    • Journal Title

      Cell Tissue Res 334

      Pages: 243-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Transforming growth factor-β induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes2008

    • Author(s)
      Kojima T, Takano K, Yamamoto T, Imamura M, Murata M, Son S, Yamaguchi H, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      Liver Int 28

      Pages: 534-545

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy.2008

    • Author(s)
      Nishikiori N, Osanai M, Chiba H, Kojima T, Inatomi S, Ohguro H, Sawada N
    • Journal Title

      Clinical Ophthalmology 2

      Pages: 233-235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma2008

    • Author(s)
      Nakayama F, Semba S, Usami Y, Chiba H, Sawada N, Yokozaki H
    • Journal Title

      Pathobiology 75

      Pages: 177-185

    • NAID

      120001408357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation.2008

    • Author(s)
      Koizumi J, Kojima T, Ogasawara N, Kamekura R, Kurose M, Go M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      Mol Pharmacol 74

      Pages: 432-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Transforming growth factor-βinduces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes.2008

    • Author(s)
      Kojima T, Takano K, Yamamoto T, Imamura M, Murata M, Son S, Yamaguchi H, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      Liver Int 28

      Pages: 534-545

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma.2008

    • Author(s)
      Nakayama F, Semba S, Usami Y, Chiba H, Sawada N, Yokozaki H
    • Journal Title

      Pathobiology 75

      Pages: 177-185

    • NAID

      120001408357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca^<2+> absorption between enterocytes2008

    • Author(s)
      Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, Uchiyama Y, Yamamoto Y, Wada T, Kojima T, Yokozaki H, Yamashita T, Kato S, Sawada N, Chiba H
    • Journal Title

      Mol Biol Cell 19

      Pages: 1912-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Heterogeneous expression of claudin-4 in human colorectal cancer : decreased claudin-4 expression at the invasive front correlates cancer invasion and metastasis2007

    • Author(s)
      Ueda J, Semba S, Chiba H, Sawada N, Seo Y, Kasuga M, Yokozaki H
    • Journal Title

      Pathobiology 74

      Pages: 32-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains.2007

    • Author(s)
      Nishikiori N, Osanai M, Chiba H, Kojima T, Ohguro H, Sawada N
    • Journal Title

      Invest Ophthalmol Vis Sci 48

      Pages: 2224-2229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells.2007

    • Author(s)
      Osanai M, Murata M, Chiba H, Kojima T, Sawada N
    • Journal Title

      Cancer Sci 98

      Pages: 1557-1562

    • NAID

      10019997370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions.2007

    • Author(s)
      Imamura M, Kojima T, Lan M, Son S, Murata M, Osanai M, Chiba H, Hirata K, Sawada N
    • Journal Title

      Exp Cell Res 313

      Pages: 1951-1962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Gastric and intestinal claudin expression at the invasive front of gastric carcinoma.2007

    • Author(s)
      Matsuda Y, Semba S, Ueda J, Fuku T, Hasuo T, Chiba H, Sawada N, Kuroda Y, Yokozaki H
    • Journal Title

      Cancer Sci 98

      Pages: 1014-1019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Induction of claudins in passaged hTERT-transfected human nasal epithelial cells with an extended life span2007

    • Author(s)
      Kurose M, Kojima T, Koizumi J, Kamekura R, Ninomiya T, Murata M, Ichimiya S, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      Cell Tissue Res 330

      Pages: 63-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Gastric and intestinal claudins expression at the invasive front of gastric carcinoma2007

    • Author(s)
      Matsuda Y, Semba S, Ueda J, Fuku T, Hasuo T, Chiba H, Sawada N, Kuroda Y, Yokozaki H
    • Journal Title

      Cancer Sci 98

      Pages: 1014-1019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Changes of gap and tight junctions during differentiation of human nasal epithelial cells using primary human nasal epithelial cells and primary human nasal fibroblast cells in a noncontact coculture system.2007

    • Author(s)
      Koizumi J, Kojima T, Kamekura R, Kurose M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      J Membr Biol 218

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity : role of retinoic acid receptor alpha agonists in colitis2007

    • Author(s)
      Osanai M, Nishikiori N, Murata M, Chiba H, Kojima T, Sawada N
    • Journal Title

      Mol Pharmacol 71

      Pages: 250-258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.2007

    • Author(s)
      Osanai M, Murata M, Nishikiori N, Chiba H, Kojima T, Sawada N
    • Journal Title

      Cancer Sci 98

      Pages: 1027-1034

    • NAID

      120002187916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains2007

    • Author(s)
      Nishikiori N, Osanai M, Chiba H, Kojima T, Ohguro H, Sawada N
    • Journal Title

      Invest Ophth Vis Sci 48

      Pages: 2224-2229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Changes of gap and tight junctions during differentiation of human nasal epithelial cells using primary human nasal epithelial cells and primary human nasal fibroblast cells in a noncontact coculture system2007

    • Author(s)
      Koizumi J, Kojima T, Kamekura R, Kurose M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      J Membr Biol 218

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] nduction of claudins in passaged hTERT-transfected human nasal epithelial cells with an extended life span.2007

    • Author(s)
      Kurose M, Kojima T, Koizumi J, Kamekura R, Ninomiya T, Murata M, Ichimiya S, Osanai M, Chiba H, Himi T, Sawada N
    • Journal Title

      Cell Tissue Res 330

      Pages: 63-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] A novel monoclonal antibody against second extracellular loop of occludin disrupts epithelial cell polarity2007

    • Author(s)
      Tokunaga Y, Kojima T, Osanai M, Murata M, Chiba H, Tobioka H, Sawada N
    • Journal Title

      J Histochem Cytochem 55

      Pages: 735-744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Expression patterns of claudin family of tight-junction proteins in the mouse prostate.2007

    • Author(s)
      Sakai N, Chiba H, Fujita H, Akashi Y, Osanai M, Kojima T, Sawada N
    • Journal Title

      Histochem Cell Biol 127

      Pages: 457-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Glial cell-derived cytokines attenuate the breakdown of vascular integrity in diabetic retinopathy2007

    • Author(s)
      Nishikiori N, Osanai M, Chiba H, Kojima T, Mitamura Y, Ohguro H, Sawada N
    • Journal Title

      Diabetes 56

      Pages: 1333-1340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Heterogeneous expression of claudin-4 in human colorectal cancer: decreased claudin-4 expression at the invasive front correlates cancer invasion and metastasis.2007

    • Author(s)
      Ueda J, Semba S, Chiba H, Sawada N, Seo Y, Kasuga M, Yokozaki H
    • Journal Title

      Pathobiology 74

      Pages: 32-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells2007

    • Author(s)
      Osanai M, Murata M, Chiba H, Kojima T, Sawada N
    • Journal Title

      Cancer Sci 98

      Pages: 1557-1562

    • NAID

      10019997370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis.2007

    • Author(s)
      Osanai M, Nishikiori N, Murata M, Chiba H, Kojima T, Sawada N
    • Journal Title

      Mol Pharmacol 71

      Pages: 250-258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Glial cell-derived cytokines attenuate the breakdown of vascular integrity in diabetic retinopathy.2007

    • Author(s)
      Nishikiori N, Osanai M, Chiba H, Kojima T, Mitamura Y, Ohguro H, Sawada N
    • Journal Title

      Diabetes 56

      Pages: 1333-1340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] A novel monoclonal antibody against the second extracellular loop of occludin disrupts epithelial cell polarity.2007

    • Author(s)
      Tokunaga Y, Kojima T, Osanai M, Murata M, Chiba H, Tobioka H, Sawada N
    • Journal Title

      J Histochem Cytochem 55

      Pages: 735-744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Journal Article] Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions2007

    • Author(s)
      Imamura M, Kojima T, Lan M, Son S, Murata M, Osanai M, Chiba H, Hirata K, Sawada N
    • Journal Title

      Exp Cell Res 313

      Pages: 1951-1962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells2007

    • Author(s)
      Osanai M, Murata M, Nishikiori N, Chiba H, Kojima T, Sawada N
    • Journal Title

      Cancer Sci 98

      Pages: 1027-1034

    • NAID

      120002187916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] Expression patterns of claudin family of tight-junction proteins in the mouse prostate2007

    • Author(s)
      Sakai N, Chiba H, Fujita H, Akashi Y, Osanai M, Kojima T, Sawada N
    • Journal Title

      Histochem Cell Biol 127

      Pages: 457-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Journal Article] The significance of interferon-γ-triggered internalization of tight junction proteins in inflammatory bowel disease.2006

    • Author(s)
      Chiba H et al.
    • Journal Title

      Sci STKE 316

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590322
  • [Journal Article] The nuclear receptor hepatocyte nuclear factor 4α acts as amorphogen to induce the formation of microvilli2006

    • Author(s)
      Chiba H, et. al.
    • Journal Title

      J Cell Biol 175

      Pages: 971-980

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] The significance of interferon-Y-triggered internalization of tight-junction proteins in inflammatory bowel disease.2006

    • Author(s)
      Chiba, H, et. al.
    • Journal Title

      Sci STKE 316

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] The significance of interferon-y-triggered internalization of tight-junction proteins in inflammatory bowel disease.2006

    • Author(s)
      Chiba H et al.
    • Journal Title

      Sci STKE. 316

    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] The nuclear receptor hepatocyte nuclear factor 4a acts as a morphogen to induce the formation of microvilli.2006

    • Author(s)
      Chiba H et al.
    • Journal Title

      J Cell Biol. 175

      Pages: 971-980

    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] The significance of interferon-γ-triggered internalization of tight-junction proteins in inflammatory bowel disease.2006

    • Author(s)
      Chiba H et al.
    • Journal Title

      Sci STKE. 316

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] The significance of interferon-γ-triggered internalization of tight-junction proteins in inflammatory bowel disease.2006

    • Author(s)
      Chiba H et al.
    • Journal Title

      Sci STKE. 316

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590322
  • [Journal Article] The nuclear receptor hepatocyte nuclear factor 4o ; acts as a morphogen to induce the formation of microvilli.2006

    • Author(s)
      Chiba, H, et. al.
    • Journal Title

      J Cell Biol 175

      Pages: 971-980

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Activation of p21^<CIP1/WAF1> gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4α.2005

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res 302

      Pages: 11-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590322
  • [Journal Article] Activation of p21CIP1/WAF1 gene and inhibition of cell proliferation by hepatocyte nuclear factor-4α.2005

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res. 302

      Pages: 11-21

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370080
  • [Journal Article] Activation of p21^<CIPI/WAFI> gene and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4α2005

    • Author(s)
      Chiba H, et. al.
    • Journal Title

      Exp Cell Res. 302

      Pages: 11-21

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Activation of p21^<CIP1/WAF1> gene and inhibition of cell proliferation by overexpression of hepatocyte unclear factore-4α.2005

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res. 302

      Pages: 11-21

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590322
  • [Journal Article] Activation of p21^<CIP1/WAF1> gene and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4α.2005

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res. 302

      Pages: 11-21

    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Activation of p21^<CIPI/WAFI> gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4a.2005

    • Author(s)
      Chiba, H, et. al.
    • Journal Title

      Exp Cell Res 302

      Pages: 11-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Journal Article] Activation of p21^<CIP1/WAF1> gene and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4α.2005

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res. 302

      Pages: 11-21

    • Data Source
      KAKENHI-PROJECT-16590322
  • [Journal Article] Activation of p21^<CIP1/WAF1> gene and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4a2005

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res 302

      Pages: 11-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370080
  • [Journal Article] 血液組織関門の形成と制御の分子機構2004

    • Author(s)
      千葉英樹 他
    • Journal Title

      福岡医学雑誌 95

      Pages: 139-145

    • NAID

      120002834501

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370080
  • [Journal Article] 血液組織関門の形成と制御の分子機構2004

    • Author(s)
      千葉英樹 他
    • Journal Title

      福岡医学雑誌 95

      Pages: 139-145

    • NAID

      120002834501

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590322
  • [Journal Article] Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morpgology in F9 embryonal carcinoma cells.2003

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res. 286

      Pages: 288-297

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370080
  • [Journal Article] Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells2003

    • Author(s)
      Chiba H et al.
    • Journal Title

      Exp Cell Res 286

      Pages: 288-297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370080
  • [Journal Article] Tight junction proteins and signal transduction pathways in hepatocytes

    • Author(s)
      Kojima T, Murata M, Yamamoto T, Lan M, Imamura M, Son S, Takano K-i, Yamaguchi H, Ito T, Tanaka S, Chiba H, Hirata K, Sawada N
    • Journal Title

      Histol Histopathol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Patent] 細胞培養補助剤2021

    • Inventor(s)
      千葉英樹、杉本幸太郎
    • Industrial Property Rights Holder
      千葉英樹、杉本幸太郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K21529
  • [Patent] 子宮体癌患者の予後予測バイオマーカー2019

    • Inventor(s)
      千葉英樹,杉本幸太郎
    • Industrial Property Rights Holder
      千葉英樹,杉本幸太郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Patent] 子宮体癌患者の予後予測マーカー2019

    • Inventor(s)
      千葉英樹, 杉本幸太郎
    • Industrial Property Rights Holder
      千葉英樹, 杉本幸太郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] CLDN4-LXR 連関による乳癌の悪性形質制御機構2023

    • Author(s)
      杉本幸太郎 、西間木 (村上)祐子 、小林信 、千葉英樹
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-23K27394
  • [Presentation] 肝受容体ホモログ -1 の異常セリンリン酸化は膵癌・肝癌の予後不良因子である2023

    • Author(s)
      小林信 、杉本幸太郎 、西間木淳 、小林靖幸 、千葉英樹
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-23K27394
  • [Presentation] ラットモノクローナル抗体の樹立と有用性2020

    • Author(s)
      千葉英樹
    • Organizer
      第5回DSANJ Bio Conference'20 Open
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] 幹細胞培養補助剤:JAM-C部分ペプチドは間葉系幹細胞の培養補助剤として有用である2019

    • Author(s)
      千葉英樹, 杉本幸太郎
    • Organizer
      ファーマラボEXPO
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] 子宮体癌患者の予後予測バイオマーカー2019

    • Author(s)
      千葉英樹, 杉本幸太郎
    • Organizer
      ファーマラボEXPO
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] ラットモノクローナル抗体の樹立と有用性-子宮体癌予後予測と悪性中皮腫の新規マーカーを例に2019

    • Author(s)
      千葉英樹
    • Organizer
      新技術説明会
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] タイト結合分子クローディンに対するモノクローナル抗体の樹立とその応用2019

    • Author(s)
      杉本幸太郎、東淳子、東智仁、千葉英樹
    • Organizer
      第108回日本病理学会
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] 細胞接着シグナルによる正常細胞機能とがん悪性形質の新規制御機構2018

    • Author(s)
      杉本幸太郎,冨川直樹,柏木惟人,小島学,村上祐子,田中瑞子,東智仁,千葉英樹
    • Organizer
      第107回日本病理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] Mutual activation of Claudin-6 and Src family kinases triggers epithelial differentiation via RARγ phosphorylation2018

    • Author(s)
      Kotaro Sugimoto, Naoki Ichikawa-Tomikawa, Korehito Kashiwagi, Tomohito Higashi, Hideki Chiba
    • Organizer
      Joint Annual Meeting of JSDB 5st and JSCB 70th
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] タイト結合分子クローディン-6の発現は子宮内膜癌の予後不良因子である2017

    • Author(s)
      小島学、杉本幸太郎、田中瑞子、柏木維人、齋藤明、冨川直樹、千葉英樹
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] タイト結合分子クローディン-6接着シグナルは子宮内膜癌の悪性形質を増強する2017

    • Author(s)
      杉本幸太郎、小島学、田中瑞子、柏木維人、冨川直樹、千葉英樹
    • Organizer
      第69回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-17K08699
  • [Presentation] クローディン-6の上皮分化誘導シグナルには、SrcとBlkが機能している2015

    • Author(s)
      冨川直樹、柏木維人、杉本幸太郎、千葉英樹
    • Organizer
      第104回日本病理学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-26670191
  • [Presentation] 幹細胞の上皮分化誘導機構において、核内受容体とCldn6シグナルがタイト結合分子の転写活性化に与える影響2015

    • Author(s)
      柏木維人、冨川直樹、杉本幸太郎、渡部哲也、柳田真衣、千葉英樹
    • Organizer
      第104回日本病理学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-26670191
  • [Presentation] タイト結合分子クローディン-4の上皮分化誘導能の解析2015

    • Author(s)
      柳沼奈々絵、冨川直樹、柏木維人、杉本幸太郎、千葉英樹
    • Organizer
      第104回日本病理学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-26670191
  • [Presentation] Src family kinase involves in the differentiation of stem cells to epithelial cells2012

    • Author(s)
      Naoki Tomikawa-Ichikawa, Kotaro Sugimoto, Risa Kanai, Hideki Chiba
    • Organizer
      In: Tight junction symposium 2012
    • Place of Presentation
      Merida, Mexico.
    • Data Source
      KAKENHI-PROJECT-23659187
  • [Presentation] Tight-junction protein claudin-6 provokes epithelial polarization and cell-cell junction formation in F9 stem cells2012

    • Author(s)
      Kotaro Sugimoto, Naoki Ichikawa-Tomikawa, Risa Kanai, Satoshi Tanaka , Norimasa Sawada, Hideki Chiba
    • Organizer
      In: Tight junction symposium 2012
    • Place of Presentation
      Merida, Mexico
    • Data Source
      KAKENHI-PROJECT-23659187
  • [Presentation] 核内受容体PPAR-γを介したヒト鼻粘膜におけるタイト結合の発現調節機構.2009

    • Author(s)
      小笠原徳子, 小島隆, 郷充, 亀倉隆太, 大國毅, 正木智之, 村田雅樹, 田中敏, 千葉英樹, 氷見徹夫, 澤田典均
    • Organizer
      第98回日本病理学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 膵癌細胞株のPKCシグナル異常におけるタイト結合蛋白の変化.2009

    • Author(s)
      伊東竜哉, 小島隆, 山口洋志, 村田雅樹, 田中敏, 千葉英樹, 平田公一, 澤田典均
    • Organizer
      第98回日本病理学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 核内受容体hepatocyte nuclear factor 4alphaは微絨毛と細胞接着の形成を誘導するモルフォルゲンとして働く2007

    • Author(s)
      千葉 英樹, 他
    • Organizer
      ワークショップ「細胞接着・細胞外基質・細胞間相互作用」第40回日本発生生物学会・第59回日本細胞生物学会大会
    • Place of Presentation
      福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390117
  • [Presentation] 内受容体hepatocyte nuclear factor 4alphaは微絨毛と細胞接着の形成を誘導するモルフォルゲンとして働く.ワークショップ「細胞接着・細胞外基質・細胞間相互作用」2007

    • Author(s)
      千葉英樹, 村田雅樹, 小山内誠, 二宮孝文, 小島隆, 澤田典均
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 肝疾患の病態とタイト結合.2007

    • Author(s)
      澤田典均, 村田雅樹, 小山内誠, 千葉英樹小島隆
    • Organizer
      第4回日本病理学会カンファレンス「肝疾患研究の最前線:現状と課題」
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 核内受容体hepatocyte nuclear factor 4alphaは微絨毛と細胞接着の形成を誘導するモルフォルゲンとして働く2007

    • Author(s)
      千葉英樹, 村田雅樹, 小山内誠, 二宮孝文, 小島隆, 澤田典均
    • Organizer
      ワークショップ「細胞接着・細胞外基質・細胞間相互作用」第40回日本発生生物学会・第59回日本細胞生物学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Presentation] 細胞間接着と極性形成の制御機構2007

    • Author(s)
      千葉英樹
    • Organizer
      第53回日本病理学会秋期特別総会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-06
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 細胞間接着と極性形成の制御機構.2007

    • Author(s)
      千葉英樹
    • Organizer
      第53回日本病理学会秋期特別総会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-06
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 核内受容体hepatocyte nuclear factor 4alphaは微絨毛と細胞接着の形成を誘導するモルフォルゲンとして働く2007

    • Author(s)
      千葉英樹, 他
    • Organizer
      ワークショップ「細胞接着・細胞外基質・細胞間相互作用」第40回日本発生生物学会・第59回日本細胞生物学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19390103
  • [Presentation] 細胞間接着と極性形成の制御機構2007

    • Author(s)
      千葉英樹
    • Organizer
      第53回日本病理学会秋期特別総会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-06
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Presentation] A novel mechanism underlying vitamin D-dependent Ca^<2+> absorption between enterocytes.2007

    • Author(s)
      千葉英樹, 他
    • Organizer
      In: 4th meeting bone biology forum
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Presentation] A novel mechanism underlying vitamin D-dependent Ca^<2+> absorption between enterocytes2007

    • Author(s)
      Chiba H
    • Organizer
      In : 4th meeting Bone Biology Forum
    • Place of Presentation
      Shizuoka
    • Data Source
      KAKENHI-PROJECT-19590398
  • [Presentation] マウス乳癌転移モデルの開発と転移関連遺伝子の探索

    • Author(s)
      宍戸奈美子、田中瑞子、冨川直樹、千葉英樹、杉野隆
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24501318
  • [Presentation] マウス転移モデルの作製とmicroarray, in vivo knockdownを用いた転移関連分子の同定

    • Author(s)
      杉野隆、千葉英樹、中島孝
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24501318
  • 1.  SAWADA Norimasa (30154149)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  KOJIMA Takashi (30260764)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 24 results
  • 3.  TOBIOKA Hirotoshi (90291559)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  TOMIKAWA Naoki (80468587)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 5.  TANAKA Mizuko (40583638)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 6.  杉本 幸太郎 (40791009)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 7.  MURATA Masaki (10404592)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 19 results
  • 8.  ENDO Toshiaki (90213595)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  柏木 維人 (50722451)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 10.  TANAKA Satoshi (30374250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 11.  INATOMI Syuichiro (10437999)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  SUGINO Takashi (90171165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  IMURA TETSUYA (00405276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  IKEDA Tatsuru (40202890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  小海 康夫 (20178239)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  小山内 誠 (60381266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  東 智仁 (70515072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  齋藤 明 (70791010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  小林 信 (60761947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 20.  沢田 典均
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 52 results
  • 21.  小船戸 康英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  丸橋 繁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  石亀 輝英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  赤澤 智宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  馬渕 洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi