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yamashita taku  山下 拓

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YAMASHITA Taku  山下 拓

山下 拓  ヤマシタ タク

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Researcher Number 00296683
Other IDs
Affiliation (Current) 2025: 北里大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 北里大学, 医学部, 教授
2015 – 2019: 北里大学, 医学部, 教授
2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 准教授
2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 准教授
2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院, 准教授 … More
2013: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育学部医学科専門課程, 准教授
2011 – 2012: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院, 講師
2002: 慶應大, 医学部, 助手
2001: 慶應義塾大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Except Principal Investigator
Basic Section 49020:Human pathology-related / Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords
Principal Investigator
頭頸部癌 / バイオマーカー / REV7 / DNA修復因子 / 遺伝子治療 / 癌細胞雄株 / ノックアウト / 癌細胞株 / ノックアウトマウス / CD109 … More / DNA修復 / 予後因子 / DNA損傷修復 / p16 / 中咽頭癌 / 未分化癌 / 甲状腺癌 / センダイウイルス / 同所移植モデル / ウイルスベクター / DNA修復遺伝子 / DNA切断 / 遺伝子修復 / リンパ節転移 / 同所移植 / 舌扁平上皮癌 / MMP阻害剤 … More
Except Principal Investigator
頭頸部癌 / REV7 / CD44 / 有効性予測 / DNA損傷乗り越え複製 / 腫瘍遺伝子変異量 / 免疫チェックポイント阻害薬 / MTI-MMP / Head and Neck Cancer / MT1-MMP Less
  • Research Projects

    (8 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (8 People)
  •  REV7は頭頸部癌の新たな予後因子となるか?

    • Principal Investigator
      籾山 香保
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Kitasato University
  •  変異導入に関わる蛋白の発現は頭頸部癌の免疫チェックポイント阻害薬適応の指標となる

    • Principal Investigator
      星野 昭芳
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Kitasato University
  •  Is CD109 useful as a biomarker or therapeutic target for head and neck cancer?Principal Investigator

    • Principal Investigator
      山下 拓
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Kitasato University
  •  REV expression as a biomarker for head and neck cancerPrincipal Investigator

    • Principal Investigator
      Yamashita Taku
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kitasato University
  •  The therapeutic efffect of Oncolytic recombinant Sendai Virus against refractory head and neck cancer.Principal Investigator

    • Principal Investigator
      Yamashita Taku
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kitasato University
      National Defense Medical College
  •  Sensitization for chemotherapy and radiation by gene induction which suppresses DNA repair in head and neck cancerPrincipal Investigator

    • Principal Investigator
      YAMASHITA Taku
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      National Defense Medical College
  •  頭頚部癌由来細胞株を用いた新規MMP阻害剤のMMP-2,9活性抑制に関する研究Principal Investigator

    • Principal Investigator
      山下 拓
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Keio University
  •  Interaction between MT1-MMP and CD44 in the invasion and metastasis of head and neck cancer

    • Principal Investigator
      FUJII Masato
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Keio University

All 2019 2017 2015 2012 Other

All Journal Article Presentation

  • [Journal Article] 5)Dual Disruption of DNA Repair and Telomere Maintenance for the Treatment of Head and Neck Cancer.2015

    • Author(s)
      Lajud SA, Nagda DA, Yamashita T, Zheng J, Tanaka N, Abuzeid WM, Civantos A, Bezpalko O, O'Malley BW Jr, Li D.
    • Journal Title

      Clin Cancer Res.

      Volume: in press Issue: 24 Pages: 6465-6478

    • DOI

      10.1158/1078-0432.ccr-14-0176

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23592544
  • [Presentation] HPV関連癌とREV7発現の検討2019

    • Author(s)
      籾山香保、宮本俊輔、清野由輩、松木崇、堤翔平、鈴木綾子、山下拓
    • Organizer
      第43回頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-17K11407
  • [Presentation] A novel treatment strategy for anaplastic thyroid carcinoma using urokinase-type plasminogen activator-dependent oncolytic recombinant Sendai virus2017

    • Author(s)
      Taku Yamashita, Yoshihiro Miyagawa, Akihiro Shiotani
    • Organizer
      2nd Congress of Asia-Pacific Society of Thyroid Surgery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462626
  • [Presentation] 腫瘍溶解性センダイウイルスによる頭頸部癌の新規治療2015

    • Author(s)
      宮川義弘, 山下拓, 田中伸吾, 田中雄也, 冨藤雅之, 荒木幸仁, 塩谷彰浩
    • Organizer
      第67回日本気管食道科学会
    • Place of Presentation
      ザ・セレクトン福島他(福島県福島市)
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-26462626
  • [Presentation] A Urokinase-type Plasminogen Activator-dependent Oncolytic Sendai Virus, Eradicates Head and Neck Squamous Cell Carcinoma.2015

    • Author(s)
      Tanaka S, Yamashita T, Araki K, Tomufuji M, Kamide D, Miyagawa Y, Shiotani A
    • Organizer
      39th Annual Meeting of Japan society of Head and Neck Oncology
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-06-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462626
  • [Presentation] DNA修復阻害によるシスプラチン増感治療.2012

    • Author(s)
      山下 拓
    • Organizer
      頭頸部癌基礎研究会
    • Place of Presentation
      島根県
    • Data Source
      KAKENHI-PROJECT-23592544
  • [Presentation] Bioknife, a urokinase-type plasminogen activator-dependent oncolytic Sendai Virus, exerminate orthotopic anaplastic thyroid carcinoma.

    • Author(s)
      Miyagawa Y, Yamashita T, Araki K, Tomufuji Y, Ueda Y, Yonematsu Y, Shiotani A
    • Organizer
      IFHNOS 5th World Congress and AHNS 2014 meeting
    • Place of Presentation
      New York
    • Year and Date
      2014-07-25 – 2014-07-30
    • Data Source
      KAKENHI-PROJECT-26462626
  • 1.  村雲 芳樹 (40324438)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  ARAKI Koji (70317220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  FUJII Masato (70129633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TASHIRO Mastsugu (70296680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  冨藤 雅之 (80327626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  石黒 隆一郎 (20296677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  籾山 香保 (50748663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  星野 昭芳 (00392382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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