OZONO Ryoji 小園亮次

Researcher Number	00304436
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2007: 広島大学, 病院, 講師 2006: 広島大学, 病院・講師 2004: Hiroshima University, Hospital, Assistant Professor, 病院・講師 2003: Hiroshima University, Medical and Dental Hospital, Assistant Professor, 医学部・歯学部附属病院, 講師 2002: Hiroshima University Medical Hospital, Assistant Professor, 医学部附属病院, 講師 2001: 広島大学, 医学部・付属病院, 助手 1999 – 2000: 広島大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Laboratory medicine Except Principal Investigator Laboratory medicine / Circulatory organs internal medicine / Laboratory medicine
Keywords	Principal Investigator Bach1 / oxidative stress / 虚血性心疾患 / 動脈硬化 / 酸化ストレス / 高血圧 / cardiovascular disease / heme oxygenase / ヘムオキシゲネース / 心肥大 … More / HO-1 / ischemic heart disease / risk factors / hypertension / atherosclerosis / telomere / aging / science of longevity / リスクファクター / テロメア / 老化 / 長寿科学 / ドーパミン / 食塩 / ノックアウトマウス / 受容体 / ドパミン … More Except Principal Investigator 動脈硬化 / endothelium / 血小板 / 血管内皮 / hypertension / platelets / atherosclerosis / 高血圧 / 反応性充血 / reactive hyperemia / nitric oxide / 高脂血症 / 加齢 / 一酸化窒素 / Animal Model / Vascular Smooth Muscle Cells / Bone Metabolism-related Factors / Vascular Calcification / Arteriosclerosis / 血管平滑筋細胞 / 骨代謝関連因子 / 血管石灰化 / inflammation / artery / shear stress / 炎症反応 / 頚動脈 / ずり応力 / aging / ultrasound / hyperemia / 超音波 / aerobic exercise / obesity / estrogen / menopause / essential hypertension / エストロゲン / 運動 / アンジオテンシン変換酵素阻害薬 / 肥満 / 閉経 / 本態性高血圧 Less

Role of Osteoprotegerin in Arterial Calcification: Development of New Animal Model
- Principal Investigator
  
  YOSHIZUMI Masao
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Hiroshima University
Assessment of tolerability against oxidative stress based on the inducible capacity of heme oxygenase-1Principal Investigator
- Principal Investigator
  
  OZONO Ryoji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  HIROSHIMA UNIVERSITY
Systematization of Non-invasive Evaluation of Atherosclerosis in Clinical Laboratory Medicine
- Principal Investigator
  
  OSHIMA Tetsuya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  HIROSHIMA UNIVERSITY
Telomere as a possible marker for aging of cardiovascular systemPrincipal Investigator
- Principal Investigator
  
  OZONO Ryoji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  HIROSHIMA UNIVERSITY
Establishment of Evaluation of Endothelial Function in Clinical Laboratory Medicine.
- Principal Investigator
  
  OSHIMA Tetsuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  HIROSHIMA UNIVERSITY
新しい昇圧因子としてのドパミン受容体機能異常の研究Principal Investigator
- Principal Investigator
  
  小園亮次
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hiroshima University
Noninvasive evaluation of endothelial function in life style-related diseases
- Principal Investigator
  
  OSHIMA Tetsuya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Laboratory medicine
- Research Institution
  HIROSHIMA UNIVERSITY

All 2007 2006 2005

All Journal Article Book

[Book] よくわかる病態生理シリーズ第2巻循環器疾患 9章高血圧 (岡田隆夫編集)2006
- Author(s)
  小園亮次(共著)
- Total Pages
  17
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-17590493
[Book] よくおかる病態生理シリーズ第2巻循環器疾患9章高血圧2006
- Author(s)
  小園亮次他
- Total Pages
  17
- Publisher
  日本医事報社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] Gene delivery of paraoxonase-1 neointiroal hyperplasia after balloon-injury in rabbits fed a high-fat diet.2007
- Author(s)
  Miyoshi M., Nakano Y., Sakaguchi T., Ogi H., Oda N., Suenari K., Kiyotani K., Ozono R., Oshima T., Yoshida T., Chayama K.
- Journal Title
  
  Hypertens Res. Vol 30
  
  Pages: 85-91
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] Reduced Expression of Heme Oxygenase-1 in Patients with Coronary Atherosclerosis.2007
- Author(s)
  Brydun, Y.Watari, Y.Yamamoto, K.Okuhara, H.Teragawa K.Chayama, F.Kono, T.Oshima, R.Ozono.
- Journal Title
  
  Hypertens Res vol 30
  
  Pages: 345-352
- NAID
  10019576575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] AT2 receptor mediates the cardioprotective effects of AT1 receptor antagonist in post myocardial infarction remodeling.2006
- Author(s)
  Y.Oishi, R.Ozono.M.Yoshizumi, M.Akishita, M.Horiuchi, T.Oshima.
- Journal Title
  
  Life Sci vol. 80
  
  Pages: 82-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] New biotechnological methods to reduce oxidative stress in the cardiovascular system focusing on the Bach1/heme oxygenase-1 pathway.2006
- Author(s)
  Ozono, Ryoji
- Journal Title
  
  Curr Pharm. Biotechnol. 7巻(2)号
  
  Pages: 87-93
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] Differential impact of family history on age-associated increase in the prevalence of hypertension and diabetes in male Japanese workers.2006
- Author(s)
  T.Shirakawa, R.Ozono, F.Kasagi, T.Oshima, N.Kamada, M.Kambe
- Journal Title
  
  Hyper tens Res vol. 29
  
  Pages: 81-87
- NAID
  10019254379
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] New biotechnological methods to reduce oxidative stress in the cardiovascular system : focusing on the Bachl/heme oxygenase-1 pathway.2006
- Author(s)
  Ozono, Ryoji
- Journal Title
  
  Curr. Pharm. Biotechnol. 7巻・2号
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] Genetic ablation the transcription, repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice.2006
- Author(s)
  Y.Yano, R.Ozono, Y.Oishi M.Kambe, M.Yoshizumi, T.Ishida, S.Omura, T.Oshima, K.Igarashi
- Journal Title
  
  Genes Cells vol. 11
  
  Pages: 791-803
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] New biotechnological methods to reduce oxidative stress in the cardiovascular system : focusing on the Bach1/heme oxygenase-1 pathway.2006
- Author(s)
  Ozono R.
- Journal Title
  
  Curr.Pharm.Biotechnol. 7(2)
  
  Pages: 87-93
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] Association oF Helicobacter pylori : infection with systemic inflammation. and endothelial dysfunction in healthy male subjects.2005
- Author(s)
  T.Oshima, R.Ozono, Y.Yano, Y.Oishi, H.Teragawa, Y.Higashi, M.Yoshizumi, M.Kambe
- Journal Title
  
  J Am Coll Cardiol vol. 19;45
  
  Pages: 1219-1222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493
[Journal Article] Effects of genetic ablation of bach1 upon, smooth muscle cell proliferation and atherosclerosis after cuff injury.2005
- Author(s)
  S.Omura, H.Suzuki, M.Toyofuku, R.Ozono, N.Kohno, K.Igarashi
- Journal Title
  
  Genes Cells voL10
  
  Pages: 277-285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590493

1. KAMBE Masayuki (70034139)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. OSHIMA Tetsuya (40233100)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
3. YOSHIZUMI Masao (20282626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHIDA Takafumi (40346482)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HIYAMA Eiso (00218744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIGASHI Yukihito (40346490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMAMOTO Hideya (70335678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAWAMATA Seiichi (30127641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OZONO Ryoji 小園 亮次

Research Projects

Research Products

Co-Researchers

Role of Osteoprotegerin in Arterial Calcification: Development of New Animal Model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment of tolerability against oxidative stress based on the inducible capacity of heme oxygenase-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Systematization of Non-invasive Evaluation of Atherosclerosis in Clinical Laboratory Medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Telomere as a possible marker for aging of cardiovascular systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of Evaluation of Endothelial Function in Clinical Laboratory Medicine.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい昇圧因子としてのドパミン受容体機能異常の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Noninvasive evaluation of endothelial function in life style-related diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] よくわかる病態生理シリーズ 第2巻 循環器疾患 9章 高血圧 (岡田隆夫 編集)2006

Author(s)

Total Pages

Publisher

Data Source

[Book] よくおかる病態生理シリーズ第2巻循環器疾患9章高血圧2006

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Gene delivery of paraoxonase-1 neointiroal hyperplasia after balloon-injury in rabbits fed a high-fat diet.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Reduced Expression of Heme Oxygenase-1 in Patients with Coronary Atherosclerosis.2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] AT2 receptor mediates the cardioprotective effects of AT1 receptor antagonist in post myocardial infarction remodeling.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] New biotechnological methods to reduce oxidative stress in the cardiovascular system focusing on the Bach1/heme oxygenase-1 pathway.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Differential impact of family history on age-associated increase in the prevalence of hypertension and diabetes in male Japanese workers.2006

Author(s)

OZONO Ryoji 小園亮次

[Book] よくわかる病態生理シリーズ第2巻循環器疾患 9章高血圧 (岡田隆夫編集)2006