Yamagata Hidehisa 山縣英久

… Alternative Names

YAMAGATA Hidehisa 山縣英久

Less

Researcher Number	00304618
Other IDs
Affiliation (Current)	2025: 天理大学, 医療学部, 教授
Affiliation (based on the past Project Information) *help	2010: Ehime University, 医学(系)研究科(研究院), 講師 2009: 愛媛大学, 医学系研究科, 講師 2009: Ehime University, 大学院・医学系研究科, 准教授 2008: Ehime University, 大学院・医学系研究科, 講師 2000 – 2001: 愛媛大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurology / Surgical dentistry Except Principal Investigator Biological Sciences
Keywords	Principal Investigator gene rearrangement / DMPK protein / multistep model / DNA sequence / linkage disequilibrium / (CTG)n repeat / myotonic dystrophy / シス効果 / 遺伝子再編成 / 遺伝子再構成 … More / DMPK蛋白 / 多段階モデル / シークエンス / 連鎖不平衡 / (CTG)リピート / 筋強直性ジストロフィー / 阻害薬開発 / 遺伝子導入 / 免疫染色 / Western ブロット / 口腔癌 / モノクローナル抗体 / 完全長 cDNA / 癌抑制遺伝子 FAT / カドヘリンスーパーファミリー / Isotyping / Westernブロット / 口腔がん / 免疫組織化学 / 完全長cDNA / FAT蛋白 … More Except Principal Investigator アポリポ蛋白C2 / アポリポ蛋白C1 / SURB遺伝子 / 第八因子 / アポリポ蛋白E / 第12染色体短腕 / 第21染色体 / ダイナミン / 罹患同胞対 / KIBRA / SORL1 / リスク遺伝子 / APPトランスジェニックマウス / アミロイドβ蛋白 / Dynamin2 / ゲノム / 多因子疾患 / アルツハイマー病 Less

がん抑制遺伝子FATを分子標的とする口腔癌の阻害薬の開発と臨床応用Principal Investigator
- Principal Investigator
  
  山縣英久
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Ehime University
Genetic study on Alzheimer Disease
- Principal Investigator
  
  TAKEDA Masatoshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Studies on the pathophysiological mechanism of myotonic dystrophyPrincipal Investigator
- Principal Investigator
  
  YAMAGATA Hidehisa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Ehime University

All 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] 図説分子病態学第4版2008
- Author(s)
  一瀬白帝, 鈴木宏治, 山縣英久, ほか
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20592363
[Journal Article] Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon 4 carriers.2008
- Author(s)
  Aidaralieva MJ, Kamino K, Kimura R, Yamamoto M, Morihara T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Kida T, Okuda J, Uema T, Yamagata H, Miki T, Akatsu H, Kosaka K, Takeda M.
- Journal Title
  
  Journal of Human Genetics 53
  
  Pages: 296-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592363
[Journal Article] The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between β amyloid production and tau phosphorylation in Alzheimer disease.2007
- Author(s)
  Kimura R, Kamino K, Yamamoto M, Nuripa A, Kida T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Yamagata H, Tabara Y, Miki T, Akatsu H, Kosaka K, Funakoshi E, Nishitomi K, Sakaguchi G, Kato A, Hattori H, Uema T, Takeda M.
- Journal Title
  
  Human Molecular Genetics 16
  
  Pages: 15-23
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Identification of homozygous deletions of the tumor suppression gene FAT in oral cancer using CGH-array2007
- Author(s)
  Nakaya, K., Yamagata, HD., Arita, N., Nakashiro, K-I., Nose, M., Miki, T., Hamakawa, H.
- Journal Title
  
  Oncogene. Aug 26(36)
  
  Pages: 5300-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.2007
- Author(s)
  Kimura R, Kamino K, Yamamoto M, Nuripa A, Kida T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Yamagata H, et al
- Journal Title
  
  Hum Mol Genet. 16(1)
  
  Pages: 15-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Albumin gene encoding FFA and beta amyloid transporter is a risk gen for Alzheimer disease.2006
- Author(s)
  Kimura R, Kamino K, Yamamoto M, Akatsu H, Uema T, Kobayashi T, Hattori H, Nuripa A, Nessa B, Kudo T, Yamagata H, miki T, Takeda M.
- Journal Title
  
  Psychiatry and Clinical Neuroscience (In press)
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Albumin gene encoding free fatty acid and β-amyloid transporter is genetically associated with Alzheimer disease.2006
- Author(s)
  Kimura R, Kamino K, Yamamoto M, Akatsu H, Uema T, Kobayashi T, Hattori H, Nuripa A, Nessa B, Kudo T, Yamagata H, miki T, Takeda M.
- Journal Title
  
  Psychiatry and Clinical Neuroscience 60
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Variations in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan.2006
- Author(s)
  Akatsu H, Yamagata H, Kawamata J, Kamino K, Takeda M, Yamamoto T, Miki T, Tooyama I, Shimohama S, Kosaka K, Okada H.
- Journal Title
  
  Dementia and Geriatric Cognitive Disorders 22
  
  Pages: 216-222
- NAID
  40015443844
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Variation in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan Akatsu2006
- Author(s)
  H., Yamagata, HD., Kawamata, J., Kamino, K., Takeda, M., Yamamoto, T., Miki, T., Tooyama, I., Shimohama, S., Kosaka, K. Dement
- Journal Title
  
  Geriatr Cogn Disord 22(3)
  
  Pages: 216-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] A novel alternative splice variant of nicastrin and its implication in Alzheimer disease.2006
- Author(s)
  Mitsuda N, Yamagata HD, Zhong W, Aoto M, Akatsu H, Uekawa N, Kamino K, Taguchi K, Yamamoto T, Maruyama M, Kosaka K, Takeda M, Kondo I, Miki T
- Journal Title
  
  Life Sciences 78
  
  Pages: 2444-2448
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Identification of hippocampus-related candidate genes for Alzheimer's disease.2005
- Author(s)
  Taguchi K, Yamagata H, Zhong W, Kamino K, Akatsu H, Hata R, Yamamoto T, Kosaka K, Takeda M, Kondo I, Miki T.
- Journal Title
  
  Ann Neurol 57(4)
  
  Pages: 585-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Identification of hippocampus-related candidate genes for Alzheimer's disease.2005
- Author(s)
  Taguchi K, Yamagata H, Zhong W, Kamino K, Akatsu H, Hata R, Yamamoto T, Kosaka K, Takeda M, Kondo I, Miki T.
- Journal Title
  
  Annals of Neurology 57・4
  
  Pages: 585-588
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Increased incidence of dementia with Lewy bodies in patients carrying the e4-allele of apolipoprotein E.2004
- Author(s)
  Akatsu H, Kamino K, Yamagata H, Isojima D, Kondo I, Yamamoto T, Kida T, Takeda M, Miki T, Kosaka K.
- Journal Title
  
  PSYCHOGERIATRICS 4
  
  Pages: 23-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer's disease.2004
- Author(s)
  Yamagata H, Chen Y, Akatsu H, Kamino K, Ito J, Yokoyama S, Yamamoto T, Kosaka K, Miki T, Kondo I.
- Journal Title
  
  Biochem Biophys Res Commun 321
  
  Pages: 320-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] TAFI polymorphisms at amino acids 147 and 325 are not risk factors for cerebral infarction.2004
- Author(s)
  Akatsu H, Yamagata H, Chen Y, Miki T, Kamino K, Takeda M, Campbell W, Kondo I, Kosaka K, Yamamoto T, Okada H.
- Journal Title
  
  British J Haematology 127
  
  Pages: 440-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Presentation] 認知症性疾患の遺伝素因2009
- Author(s)
  山縣英久
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20592363

1. KAMINO Koujin (40307955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. TAKEDA Masatoshi (00179649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. MORIHARA Takeshi (90403196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TANAKA Toshihisa (10294068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. AKATSU Hiroyasu (00399734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. MAEDA Kiyoshi (80116251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ARAI Heii (50167988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAJIMA Kenji (70144673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAGUCHI Keiko (20457378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. SHIBATA Nobuto (50365615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAMOTO Yasusji (00324921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
12. WADA kenji (60346351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIKI Tetsuro (00174003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KONDO Ikuko (20110489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NOMURA Takuo (20322274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KIMURA Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. HAYASHI Noriyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YOKOKOJI Mikiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamagata Hidehisa 山縣 英久

YAMAGATA Hidehisa 山縣 英久

Research Projects

Research Products

Co-Researchers

がん抑制遺伝子FATを分子標的とする口腔癌の阻害薬の開発と臨床応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic study on Alzheimer Disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the pathophysiological mechanism of myotonic dystrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 図説 分子病態学 第4版2008

Author(s)

Publisher

Data Source

[Journal Article] Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon 4 carriers.2008

Author(s)

Journal Title

Data Source

[Journal Article] The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between β amyloid production and tau phosphorylation in Alzheimer disease.2007

Author(s)

Journal Title

Data Source

[Journal Article] Identification of homozygous deletions of the tumor suppression gene FAT in oral cancer using CGH-array2007

Author(s)

Journal Title

Data Source

[Journal Article] The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.2007

Author(s)

Journal Title

Data Source

[Journal Article] Albumin gene encoding FFA and beta amyloid transporter is a risk gen for Alzheimer disease.2006

Author(s)

Journal Title

Data Source

[Journal Article] Albumin gene encoding free fatty acid and β-amyloid transporter is genetically associated with Alzheimer disease.2006

Author(s)

Journal Title

Data Source

[Journal Article] Variations in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Variation in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan Akatsu2006

Author(s)

Journal Title

Data Source

[Journal Article] A novel alternative splice variant of nicastrin and its implication in Alzheimer disease.2006

Author(s)

Journal Title

Data Source

[Journal Article] Identification of hippocampus-related candidate genes for Alzheimer's disease.2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of hippocampus-related candidate genes for Alzheimer's disease.2005

Author(s)

Journal Title

Data Source

[Journal Article] Increased incidence of dementia with Lewy bodies in patients carrying the e4-allele of apolipoprotein E.2004

Author(s)

Journal Title

Data Source

[Journal Article] Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer's disease.2004

Author(s)

Journal Title

Data Source

Yamagata Hidehisa 山縣英久

YAMAGATA Hidehisa 山縣英久

[Book] 図説分子病態学第4版2008