YAMANOUCHI Satoshi 山内聡

Researcher Number	00307638
Affiliation (based on the past Project Information) *help	2015: 東北大学, 大学院医学系研究科, 講師 2014 – 2015: 東北大学, 医学(系)研究科(研究院), 講師 2012 – 2014: 東北大学, 医学(系)研究科(研究院), 助教 2012: 東北大学, 大学院・医学系研究科, 教授 2011: 東北大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Except Principal Investigator Emergency medicine
Keywords	Except Principal Investigator ミトコンドリア / damage control / alarmins / 凝固線溶異常 / DIC / 凝固障害 / ダメージ関連分子パターン / 集中治療 / 血液凝固異常 / 外傷 … More / 感染 / 熱傷 / 局所投与 / 一酸化炭素 / second hit phenomenon / 重傷熱傷 / 急性肺水腫 / 診断基準 / 肺血管透過性 / 肺血管外水分量 / 急性呼吸窮迫症候群 / 急性肺損傷 Less

Understanding the pathophysiology and establishing the therapeutic strategy for trauma-induced coagulopathy in patients with severe trauma
- Principal Investigator
  
  Kushimoto Shigeki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Tohoku University
一酸化炭素局所投与による熱傷後敗血症の生存率向上効果の検討
- Principal Investigator
  
  赤松順寛
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Tohoku University
Analysis of extravascular lung water dynamics and exhaustive evaluation of pulmonary epithelial metabolites to establish a novel therapeutic approach for acute lung injury/ acute respiratory distress syndrome
- Principal Investigator
  
  KUSHIMOTO Shigeki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Tohoku University

All 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Efficacy of a high FFP:PRBC transfusion ratio on the survival of severely injured patients: a retrospective study in a single tertiary emergency center in Japan.2014
- Author(s)
  Kudo D, Sasaki J, Akaishi S, Yamanouchi S, Koakutsu T, Endo T, Sato T, Nomura R, Yuzawa H, Kobayashi M, Shinozawa Y, Kushimoto S
- Journal Title
  
  Surg Today
  
  Volume: 44 Pages: 653-661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462810
[Journal Article] Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: Time-course and the association with clinical status2013
- Author(s)
  Yamanouchi S, Kudo D, Yamada M, Miyagawa N, Furukawa H, Kushimoto S.
- Journal Title
  
  J Crit Care
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592023
[Journal Article] PiCCO Pulmonary Edema Study Group. Relationship between extravascular lung water and severity categories of acute respiratory distress syndrome by the Berlin definition2013
- Author(s)
  Kushimoto S, Endo T, Yamanouchi S, Sakamoto T, Ishikura H, Kitazawa Y, Taira Y, Okuchi K, Tagami T, Watanabe A, Yamaguchi J, Yoshikawa K, Sugita M, Kase Y, Kanemura T, Takahashi H, Kuroki Y, Izumino H, Rinka H, Seo R, Takatori M, Kaneko T, Nakamura T, Irahara T, Saito N
- Journal Title
  
  Crit Care
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592023
[Journal Article] Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: time course and the association with clinical status.2013
- Author(s)
  Yamanouchi S, Kudo D, Yamada M, Miyagawa N, Furukawa H, Kushimoto S.
- Journal Title
  
  J Crit Care
  
  Volume: 28 Pages: 1027-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462810
[Journal Article] 急性期侵襲病態におけるミトコンドリアの多面的役割の可能性.2013
- Author(s)
  久志本成樹、山内聡、工藤大介、宮川乃理子
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 3 Pages: 316-322
- Data Source
  KAKENHI-PROJECT-25462810
[Journal Article] PiCCO Pulmonary Edema Study Group. The clinical usefulness of extravascular lung water and pulmonary vascular permeability index to diagnose and characterize pulmonary edema: a prospective multicenter study on the quantitative differential diagnostic definition for acute lung injury/acute respiratory distress syndrome2012
- Author(s)
  Kushimoto S, Taira Y, Kitazawa Y, Okuchi K, Sakamoto T, Ishikura H, Endo T, Yamanouchi S, Tagami T, Yamaguchi J, Yoshikawa K, Sugita M, Kase Y, Kanemura T, Takahashi H, Kuroki Y, Izumino H, Rinka H, Seo R, Takatori M, Kaneko T, Nakamura T, Irahara T, Saito N, Watanabe A
- Journal Title
  
  Critical Care
  
  Volume: 16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592023
[Presentation] 外傷急性期における凝固線溶および炎症反応にはalarminsとしてのmitochondrial DNAが関与する2015
- Author(s)
  宮川乃理子、工藤大介、山内　聡、久志本成樹
- Organizer
  第29回日本外傷学会学術集会
- Place of Presentation
  札幌市　札幌コンベンションセンター
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] The response of coagulation and fibrinolysis system was different between elderly and non-elderly patients with severe sepsis2014
- Author(s)
  Daisuke Kudo, Satoshi Yamanouchi, Takeaki Sato, Ryosuke Nomura, Taku Omura, Noriko Miyagawa and Shigeki Kushimoto
- Organizer
  International Symposium of Intensive Care and Emergency Medicine
- Place of Presentation
  Brussel, Belgium
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] 重症敗血症における炎症･免疫応答は年齢により異なる2014
- Author(s)
  工藤大介、山内聡、遠藤智之、佐藤武揚、古川宗、野村亮介、藤田基生、大村拓、宮川乃理子、久志本成樹
- Organizer
  第41回日本集中治療医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] 急性期侵襲病態におけるalarmins―敗血症、外傷、院外心停止における役割は同一ではない2014
- Author(s)
  久志本成樹、山内　聡、工藤大介、宮川乃理子、大村　拓
- Organizer
  第41回日本集中治療医学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] 重症敗血症病態形成におけるalarminsの関与―外傷、院外心停止との比較から2013
- Author(s)
  久志本成樹、山内　聡、野村亮介、工藤大介、古川　宗、小圷知明、浅沼敬一郎、瀬尾亮太、前澤翔太
- Organizer
  第４１回日本救急医学会総会・学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] 心停止後症候群における全身性炎症反応―alarminsに起因しない炎症反応が関与する2013
- Author(s)
  久志本成樹、山内　聡、遠藤智之、工藤大介、古川　宗、宮川乃理子、大村　拓、松村隆志、入野田　崇
- Organizer
  第４１回日本救急医学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] PiCCO肺水腫study group:Berlin DefinitionによるARDS分類は肺血管外水分量増加と肺血管透過性亢進を反映する2013
- Author(s)
  久志本成樹、山内聡、遠藤智之、古川宗
- Organizer
  第40回日本集中治療医学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-22592023
[Presentation] Multidisciplinary damage control surgery using interventional radiology in patients with severe trauma2013
- Author(s)
  Shigeki Kushimoto, Satoshi Yamanouchi, Daisuke Kudo, Takashi Irinoda, Takeaki Sato, Motoo Fujita, Noriko Miyagawa, Taku Omura, and Syota Maezawa
- Organizer
  The 7th Asian Conference on Emergency Medicine
- Place of Presentation
  Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] Mitochondrial DNA Levels In Patients With Trauma and Severe Sepsis: Time-course and The Association With Clinical Status2013
- Author(s)
  Yamanouchi, Daisuke Kudo (Presenter), Shigeki Kushimoto
- Organizer
  International Symposium Anatomical Science for advance in health and clinical therapy: Asahct2013
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] 外傷急性期における線溶系反応と血小板数の推移は年齢と関係する2013
- Author(s)
  工藤大介、大村拓、山内聡、中川敦寛、佐藤武揚、古川宗、野村亮介、藤田基生、久志本成樹
- Organizer
  第27回日本外傷学会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] PiCCO肺水腫study group.敗血症急性期における心収縮能低下時の拡張末期心臓容量による前負荷の評価には注意が必要である2012
- Author(s)
  久志本成樹、遠藤智之、山内聡、野村亮介、工藤大介
- Organizer
  第39回日本集中治療医学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-22592023
[Presentation] 敗血症および外傷急性期におけるmitochondrial DNA、HMGB-1動態と病態形成への可能性2012
- Author(s)
  久志本成樹、山内聡、遠藤智之、野村亮介、工藤大介、古川宗、宮川乃理子、大村拓
- Organizer
  第40回日本救急医学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22592023
[Presentation] 敗血症急性期心収縮能低下例では拡張末期心臓血液容量による前負荷の評価には注意を要する2012
- Author(s)
  久志本成樹、遠藤智之、山内聡、野村亮介、工藤大介
- Organizer
  第40回日本救急医学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22592023
[Presentation] 鈍的外傷によるDAMPsレベルの上昇は外傷後炎症反応に関連する可能性がある2012
- Author(s)
  久志本成樹、山内聡、遠藤智之、工藤大介、宮川乃理子、大村拓
- Organizer
  第26回日本外傷学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22592023
[Presentation] 急性期侵襲病態におけるalarminsの役割は同一ではない：重症敗血症、外傷、心停止症候群症例の比較
- Author(s)
  久志本成樹、山内　聡、工藤大介、宮川乃理子、大村　拓
- Organizer
  第42回日本救急医学会学術集会
- Place of Presentation
  福岡：福岡国際会議場
- Year and Date
  2014-10-28 – 2014-10-30
- Data Source
  KAKENHI-PROJECT-25462810
[Presentation] 重症敗血症における血液凝固線溶反応は年齢により異なる
- Author(s)
  工藤大介、山内聡、久志本成樹
- Organizer
  第24回バイオメディカルフォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25462810

1. KUSHIMOTO Shigeki (50195434)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. KUDO Daisuke (30455844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. MASUNO Tomohiko (00318528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SATO Norio (30409205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MIYAUCHI Masato (60312063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIRAKAWA Keiko (30165162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOKOTA Hiroyuki (60182698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ENDO Tomoyuki (00400317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. YAMADA MITSUHIRO (00396483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. FURUKAWA HAJIME (30624853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 赤松順寛 (50302112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 藤田基生 (80579756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 宮川乃理子 (10535074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 矢野寿一 (20374944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMANOUCHI Satoshi 山内 聡

Research Projects

Research Products

Co-Researchers

Understanding the pathophysiology and establishing the therapeutic strategy for trauma-induced coagulopathy in patients with severe trauma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

一酸化炭素局所投与による熱傷後敗血症の生存率向上効果の検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of extravascular lung water dynamics and exhaustive evaluation of pulmonary epithelial metabolites to establish a novel therapeutic approach for acute lung injury/ acute respiratory distress syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Efficacy of a high FFP:PRBC transfusion ratio on the survival of severely injured patients: a retrospective study in a single tertiary emergency center in Japan.2014

Author(s)

Journal Title

Data Source

[Journal Article] Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: Time-course and the association with clinical status2013

Author(s)

Journal Title

Data Source

[Journal Article] PiCCO Pulmonary Edema Study Group. Relationship between extravascular lung water and severity categories of acute respiratory distress syndrome by the Berlin definition2013

Author(s)

Journal Title

Data Source

[Journal Article] Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: time course and the association with clinical status.2013

Author(s)

Journal Title

Data Source

[Journal Article] 急性期侵襲病態におけるミトコンドリアの多面的役割の可能性.2013

Author(s)

Journal Title

Data Source

Author(s)

Journal Title

Data Source

[Presentation] 外傷急性期における凝固線溶および炎症反応にはalarminsとしてのmitochondrial DNAが関与する2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The response of coagulation and fibrinolysis system was different between elderly and non-elderly patients with severe sepsis2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 重症敗血症における炎症･免疫応答は年齢により異なる2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 急性期侵襲病態におけるalarmins―敗血症、外傷、院外心停止における役割は同一ではない2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 重症敗血症病態形成におけるalarminsの関与―外傷、院外心停止との比較から2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 心停止後症候群における全身性炎症反応―alarminsに起因しない炎症反応が関与する2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] PiCCO肺水腫study group:Berlin DefinitionによるARDS分類は肺血管外水分量増加と肺血管透過性亢進を反映する2013

Author(s)

Organizer

Place of Presentation

YAMANOUCHI Satoshi 山内聡