TANAKA Yujiro 田中裕二郎

… Alternative Names

TANAKA Yuujirou 田中裕二郎

田中裕二郎タナカユウジロウ

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Researcher Number	00311613
Affiliation (based on the past Project Information) *help	2014 – 2015: 東京医科歯科大学, 難治疾患研究所, 准教授 2011: 東京医科歯科大学, 難治疾患研究所, 准教授 2010: Tokyo Medical and Dental University, 大学院・疾患生命科学研究部, 准教授 2009: Tokyo Medical and Dental University, 疾患生命科学研究部, 准教授 2008: Tokyo Medical and Dental University, 大学院・疾患生命科学研究部, 准教授 2000 – 2001: 千葉大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Biological Sciences / Human genetics / Biological Sciences / 基礎ゲノム科学 Except Principal Investigator Pathological medical chemistry / General medical chemistry
Keywords	Principal Investigator クロマチン構造 / ASH1 / 遺伝子発現制御 / FRETプローブ / リジルエンドペプチダーゼ / FRET / ヒストン修飾 / 白血病 / エピジェネティック / 細胞分化 … More / 胸腺 / Trithorax / SAB1 / K562細胞 / CRISPR/Cas9システム / ノックアウトマウス / ChIP-seq解析 / Trithoraxグループ / サラセミア / グロビン遺伝子 / 初期発生 / 共焦点顕微鏡 / in vivoイメージング / メチル化 / ヒストン修飾酵素 / 可視化 / 酵素活性 / ヒストンメチル基転移酵素 / 脱メチル化酵素 / メチル基転移酵素 … More Except Principal Investigator がん抑制 / 発がん / TRAIL受容体 / 動物モデル / 抗がん治療 / モデルマウス / Wnt / p53 / ATF3 / ストレス応答遺伝子 / ＤＲ５ / 細胞死受容体 / 抗がん剤 / ｐ５３ / ＡＴＦ３ / 遺伝子改変マウス / ストレス応答 / System biology / 網羅的ChIP-chip / 肥満マクロファージ / Toll-like receptor 4 / DNA修複 / ATF3標的遺伝子p15 / Alternate promoter / ストレス応答遺伝子ATF3 / がん治療 / ATF3遺伝子改変マウス / p53-ATF3経路 / 標的遺伝子 / 新規プロモーター / 転写因子ATF3 / 遺伝制御 / ゲノム医化学 Less

グロビン遺伝子スイッチングのエピジェネティック分子基盤Principal Investigator
- Principal Investigator
  
  田中裕二郎
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Medical and Dental University
Role of ATF3 in oncogenesis and tumor suppression of model mice
- Principal Investigator
  
  KITAJIMA Shigetaka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
初期胚のヒストン修飾酵素活性をイメージングするPrincipal Investigator
- Principal Investigator
  
  田中裕二郎
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Gene expression of transcriptional repressor ATF3 and its biological role
- Principal Investigator
  
  KITAJIMA Shigetaka
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Spacio-temporal analysis of histone modification by FRET probesPrincipal Investigator
- Principal Investigator
  
  TANAKA Yuujirou
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Tokyo Medical and Dental University
新規クロマチン構造調節因子SAB1によるT細胞分化制御機構Principal Investigator
- Principal Investigator
  
  田中裕二郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
T細胞のクロマチン構造調節因子と発ガンPrincipal Investigator
- Principal Investigator
  
  田中裕二郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University

All 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent

[Journal Article] Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice.2013
- Author(s)
  Lee YS, Sasaki T, Kobayashi M, Kikuchi O, Kim HJ, Yokota-Hashimoto H, Shimpuku M, Susanti VY, Ido-Kitamura Y, Kimura K, Inoue H, Tanaka-Okamoto M, Ishizaki H, Miyoshi J, Ohya S, Tanaka Y, Kitajima S, Kitamura T.
- Journal Title
  
  Diabetologia
  
  Volume: 56(6) Issue: 6 Pages: 1383-1393
- DOI
  10.1007/s00125-013-2879-z
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134502, KAKENHI-PROJECT-23300274, KAKENHI-PROJECT-24590373, KAKENHI-PROJECT-24650487, KAKENHI-PUBLICLY-25134708
[Journal Article] Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.2012
- Author(s)
  Taketani K, Kawauchi J, Tanaka-Okamoto M, Ishizaki H, Tanaka Y, Sakai T, Miyoshi J, Maehara Y, Kitajima S.
- Journal Title
  
  Oncogene
  
  Volume: 31(17) Issue: 17 Pages: 2210-21
- DOI
  10.1038/onc.2011.397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700878, KAKENHI-PUBLICLY-23134502, KAKENHI-PROJECT-23701071, KAKENHI-PROJECT-24590373, KAKENHI-PLANNED-24118002
[Journal Article] Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression.2011
- Author(s)
  Tanaka, Y
- Journal Title
  
  PLoS One
  
  Volume: 6(11) Issue: 11 Pages: e28171-e28171
- DOI
  10.1371/journal.pone.0028171
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22116504
[Journal Article] Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/92010
- Author(s)
  Mori S, Iwase K, Iwanami N, Tanaka Y, Kagechika H, Hirano T.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 18 Pages: 8158-8166
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22116504
[Journal Article] Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.2010
- Author(s)
  Mori S, Iwase K, Iwanami N, Tanaka Y, Kagechika H, Hirano T.
- Journal Title
  
  Bioorg Med Chem. 18
  
  Pages: 8158-8166
- Data Source
  KAKENHI-PROJECT-20510183
[Journal Article] Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/92010
- Author(s)
  Mori S, Iwase K, Iwanami N, Tanaka Y, Kagechika H, Hirano T.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 18 Pages: 8158-8166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510183
[Journal Article] Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells.2009
- Author(s)
  Miyazaki K, Inoue S, Yamada K, Watanabe M, Liu Q, Watanabe T, Adachi M, Tanaka Y, Kitajima S
- Journal Title
  
  Nucleic Acids Res. Vol37
  
  Pages: 1438-1451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590302
[Journal Article] Regulation of early T cell development by PHD finger of histone lysine methyltransferase ASH12008
- Author(s)
  Tanaka Y, Nakayama Y, Tani guchi M, Kioussis D
- Journal Title
  
  Biochem Biophys Res Commun 365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510183
[Patent] ヒストン修飾酵素活性測定法
- Inventor(s)
  田中裕二郎
- Industrial Property Rights Holder
  田中裕二郎
- Data Source
  KAKENHI-PROJECT-20510183
[Presentation] ストレス応答におけるP53-ATF3間の機能的相互作用とその働き2012
- Author(s)
  枝川　真、川内　潤也、井上　允、内田　洋平、田中裕二郎、Paul　Sheridan、山口　類、井元　清哉、宮野　悟、前原　喜彦、北嶋　繁孝
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590373
[Presentation] Regulation of DUX4 gene expression by ASH1 in facioscaplohumeral muscular dystrophy2012
- Author(s)
  田中裕二郎
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PUBLICLY-22116504
[Presentation] ストレス応答遺伝子ATFはCamptothecinによるDR5発現を正に制御する2010
- Author(s)
  武谷憲二、川内潤也、田中裕二郎、前原喜彦、北嶋繁孝
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590302
[Presentation] 細胞内ヒストン修飾酵素活性の測定2010
- Author(s)
  田中裕二郎
- Organizer
  定量生物学の会第3回年会
- Place of Presentation
  東京大学生産技術研究所(東京都)
- Data Source
  KAKENHI-PUBLICLY-22116504
[Presentation] ストレス応答遺伝子ATF3はCamptothecinによるDR5発現を正に制御する2010
- Author(s)
  武谷憲二、川内潤也、田中裕二郎、前原喜彦、北嶋繁孝
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21590302
[Presentation] 細胞内ヒストン修飾酵素活性の測定2010
- Author(s)
  田中裕二郎
- Organizer
  定量生物学の会第3回年会
- Place of Presentation
  東京大学生産技術研究所(東京都)
- Data Source
  KAKENHI-PROJECT-20510183
[Presentation] ATF3によるmicroRNAの発現制御機構2010
- Author(s)
  佐々木かおり、川内潤也、田中裕二郎、北嶋繁孝
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590302
[Presentation] システムズ・バイオテクノロジーによるATF3標的遺伝子の網羅的探索2009
- Author(s)
  中村絢、田中裕二郎、森岡勝樹、武谷憲二、川内潤也、安達(玉盛)三美、田中博、北嶋繁孝
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590302
[Presentation] ATF3(activating transcription factor3)による転写抑制のメカニズム2009
- Author(s)
  劉芹、川内潤也、小澤高嶺、山田一彦、宮崎敬介、田中裕二郎、北嶋繁孝
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590302
[Presentation] ヒストンメチル基転移酵素ASHlによるHox遺伝子発現制御2008
- Author(s)
  Tanaka Y
- Organizer
  日本分子生物学会・日本生化学学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20510183

1. KITAJIMA Shigetaka (30186241)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. KAWAUCHI Junya (20544498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results

TANAKA Yujiro 田中 裕二郎

TANAKA Yuujirou 田中 裕二郎

田中 裕二郎 タナカ ユウジロウ

Research Projects

Research Products

Co-Researchers

グロビン遺伝子スイッチングのエピジェネティック分子基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of ATF3 in oncogenesis and tumor suppression of model mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

初期胚のヒストン修飾酵素活性をイメージングするPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Gene expression of transcriptional repressor ATF3 and its biological role

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spacio-temporal analysis of histone modification by FRET probesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規クロマチン構造調節因子SAB1によるT細胞分化制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

T細胞のクロマチン構造調節因子と発ガンPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/92010

Author(s)

Journal Title

Data Source

[Journal Article] Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.2010

Author(s)

Journal Title

Data Source

[Journal Article] Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/92010

Author(s)

Journal Title

Data Source

[Journal Article] Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of early T cell development by PHD finger of histone lysine methyltransferase ASH12008

TANAKA Yujiro 田中裕二郎

TANAKA Yuujirou 田中裕二郎

田中裕二郎タナカユウジロウ