Hosoi Haruko 細井晴子

… Alternative Names

細井晴子ホソイハルコ

HOSOI Haruko 細井晴子

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Researcher Number	00313396
Other IDs	https://orcid.org/0000-0003-2316-5492
Affiliation (Current)	2024: 東邦大学, 理学部, 准教授
Affiliation (based on the past Project Information) *help	2022: 東邦大学, 理学部, 准教授 2017 – 2020: 東邦大学, 理学部, 准教授 2010 – 2014: 東邦大学, 理学部, 講師 2011: 東邦大学, 理学部生物分子科学科, 講師 2009 – 2011: 東邦大学, 理学部・生物分子科学科, 講師 2008: 東邦大学, 理学部生物分子科学科, 講師
Review Section/Research Field	Principal Investigator Physical chemistry / Basic Section 32010:Fundamental physical chemistry-related Except Principal Investigator Physical chemistry / Science and Engineering
Keywords	Principal Investigator 蛍光タンパク質 / 発光メカニズム / 緑色蛍光タンパク質 / 黄色蛍光タンパク質 / 蛍光寿命 / 時間分解蛍光分光法 / 高次構造ダイナミクス / 蛍光異方性 / 蛍光共鳴エネルギー移動 / 構造緩和 … More / 会合 / レーザー分光法 / 変異体作製 / 結晶構造解析 / 水素結合 / 立体効果 / 蛍光メカニズム / X線結晶構造解析 / 発色団モデル化合物 / 二光子蛍光メカニズム / 高振動励起S1状態 / 電子励起S2状態 / eGFP / HBDI / マルチプレックス二光子吸収分光法 … More Except Principal Investigator ニッケル修飾ガラス表面 / Hisタグ / リシン / システイン / パラニトロアニリン / ヘテロダイン検出電子和周波発生 / セグメント / ヘテロダイン検出電子和周波発生分光法 / ヘテロダイン検出振動和周波発生分光法 / ポリペプチド / 和周波発生分光 / ヘテロダイン検出 / 円二色性 / 二次非線形感受率 / 配向 / 高次構造 / タンパク質 / 時空間分解計測 / 単一分子計測 / 分子複雑系 / 時空間分光計測 / 生体関連分子 / 界面 / 複雑分子系 / 相関分光 / 非線形分光 / 超高速分光 / ダイナミクス / 凝縮相 Less

Dynamic higher-order conformational changes control the fluorescence lifetime of fluorescent proteinsPrincipal Investigator
- Principal Investigator
  
  細井晴子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 32010:Fundamental physical chemistry-related
- Research Institution
  Toho University
Correlation between the fluorescence lifetime and the local environment of the chromophore: Universal nature to fluorescent proteins from the jellyfish Aequorea VictoriaPrincipal Investigator
- Principal Investigator
  
  HOSOI Haruko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical chemistry
- Research Institution
  Toho University
Hidden electronic excited state of enhanced green fluorescent proteinPrincipal Investigator
- Principal Investigator
  
  HOSOI Haruko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical chemistry
- Research Institution
  Toho University
Protein Structure Analysis by Second-order Nonlinear Spectroscopy
- Principal Investigator
  
  YAMAGUCHI Shoichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Study of complex molecular systems by advanced molecular spectroscopy
- Principal Investigator
  
  TAHARA Tahei
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2022 2019 2017 2015 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 月刊「細胞」2023年 4月臨時増刊号　蛍光タンパク質センサー　（蛍光タンパク質の機能と構造不均一性の関係）2023
- Author(s)
  細井晴子
- Total Pages
  5
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-22K05027
[Book] "二光子吸収材料の非線形光学スペクトル測定"高効率二光子吸収材料の開発と応用2011
- Author(s)
  山口祥一, 細井晴子, 田原太平
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Diverse Fluorescence Resonance Energy Transfer Processes Originating from the Conformational Heterogeneity of the Calcium Indicator Yellow Cameleon YC3.602023
- Author(s)
  Tsubota Hiroki、Kinoshita Yuna、Shigeno Mamoru、Hosoi Haruko
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 127 Issue: 17 Pages: 3839-3850
- DOI
  10.1021/acs.jpcb.3c00881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05027
[Journal Article] Solvent Dependence of Two-photon Absorption Spectra of the Enhanced Green Fluorescent Protein (eGFP) Chromophore2015
- Author(s)
  Haruko Hosoi, Ryo Tayama, Satoshi Takeuchi, and Tahei Tahara
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 印刷中 Pages: 32-36
- DOI
  10.1016/j.cplett.2015.04.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24550033, KAKENHI-PLANNED-25104005, KAKENHI-PROJECT-25248009
[Journal Article] Smaller 145th Residue Makes Fluorescent Protein Non-Fluorescent: Fluorescence Lifetimes of Enhanced Yellow Fluorescent Protein (eYFP) Y145 Mutants and H148 Mutants2015
- Author(s)
  Haruko Hosoi, Sakiko Hazama, and Yuri Takeda
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 618 Pages: 186-191
- DOI
  10.1016/j.cplett.2014.11.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24550033
[Journal Article] Physisorption gives narrower orientational fistribution than chemisorption on a glass surface : A polarization-sensitive linear and nonlinear optical study2010
- Author(s)
  Shoichi Yamaguchi, Haruko Hosoi, Megumi Yamashita, Pratik Sen, Tahei Tahara
- Journal Title
  
  J.Phys.Chem.Letters
  
  Volume: 1 Pages: 2662-2665
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Physisorption Gives Narrower Orientational Distribution than Chemisorption on a Glass Surface: A Polarization-Sensitive Linear and Nonlinear Optical Study2010
- Author(s)
  Shoichi Yamaguchi, Haruko Hosoi, Megumi Yamashita, Pratik Sen, and Tahei Tahara
- Journal Title
  
  J. Phys. Chem. Lett
  
  Volume: 1 Pages: 2662-2665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350014
[Journal Article] Physisorption gives narrower orientational distribution than chemisorption on a glass surface: A polarization-sensitive linear and nonlinear optical study2010
- Author(s)
  S. YAMAGUCHI, H. HOSOI, M. YAMASHITA, P. SEN, T. TAHARA
- Journal Title
  
  J. Phys. Chem. Letters
  
  Volume: 1 Pages: 2662-2665
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] 超短パルスレーザーを用いた先端的分光計測による蛍光タンパク質の発光機構の研究2009
- Author(s)
  細井晴子、山口祥一、田原太平
- Journal Title
  
  レーザー研究 37(10)
  
  Pages: 734-738
- NAID
  10025517305
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Picosecond time-resolved fluorescence study of poly vinyl methylether aqueous solution2009
- Author(s)
  Tsutomu SAKAMAKI, Tatsuya FUJINO, Haruko HOSOI, Tahei TAHARA, Takashi KORENAGA
- Journal Title
  
  Chem.Phys.Lett. 468(4-6)
  
  Pages: 171-175
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Direct observation of time-dependent photoluminescence spectral shift in CdS nanoparticles synthesized in polymer solutions2009
- Author(s)
  Debabrata MANDAL, Haruko HOSOI, Uma CHATTERJEE, Tahei TAHARA
- Journal Title
  
  J.Chem.Phys. 130(3)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Solvation structure on polyacrylamide fine particle surface studied by picoseconds time-resolved fluorescence spectroscopy2008
- Author(s)
  T. Sakamaki, T. Fujino, H. Hosoi, T. Tahara, and T. Korenaga
- Journal Title
  
  Chem. Lett. 37
  
  Pages: 980-981
- NAID
  10024282611
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Hidden Electronic State of Enhanced Green Fluorescence Protein2008
- Author(s)
  H. HOSOI, S. YAMAGUCHI, H. MIZUNO, A. MIYAWAKI, T. TAHARA
- Journal Title
  
  J. Chem. Phys. B
  
  Volume: 112 Pages: 2761-2763
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Hidden electronic state of enhanced green fluorescent protein2008
- Author(s)
  H. Hosoi, S. Yamaguchi, H. Mizuno, A. Miyawaki, T. Tahara
- Journal Title
  
  J. Phys. Chem. B 112
  
  Pages: 2761-2763
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Hidden Electronic state of Enhanced Green Fluorescence Protein2008
- Author(s)
  H. Hosoi, S. Yamaguchi, H. Mizuno, A. Miyawaki and T. Tahara
- Journal Title
  
  Chem. Phys. B. 112
  
  Pages: 2761-2763
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Femtosecond/picosecond time-resolved fluorescence study of hydorphilic polymer fine particles2007
- Author(s)
  D. Nanjo, H. Hosoi, T. Fujino, T. Tahra, and T. Korenaga
- Journal Title
  
  J. Phys, Chem. B 111
  
  Pages: 2759-2764
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] The excited-state structure and the dynamics of 1,3,5-tris (phenylethynyl) benzene as studied by Raman and time-resolved fluorescence spectroscopy2007
- Author(s)
  T. Nomoto, H. Hosoi. T. Fujino, T. Tahara, and H. Hamaguchi
- Journal Title
  
  J. Phys. Chem. A 111
  
  Pages: 2907-2912
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Journal Article] Hidden electronic state of enhanced green fluorescent protein
- Author(s)
  H. Hosoi, S. Yamaguchi, H. Mizuno, A. Miyawaki, and T. Tahara
- Journal Title
  
  J. Phys. Chem. B (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] 時間分解分光法による緑色蛍光タンパク質eGFP Y145変異体の蛍光寿命の決定と黄色蛍光タンパク質eYFPとの比較2023
- Author(s)
  木ノ下佑奈、重野守、間紗希子、内田朗、宮武秀行、細井晴子
- Organizer
  日本化学会　第103春期年会
- Data Source
  KAKENHI-PROJECT-22K05027
[Presentation] 時間分解蛍光分光法によるカルシウムセンサータンパク質YC3.60の蛍光共鳴エネルギー移動過程の解明2022
- Author(s)
  坪田空樹、細井晴子
- Organizer
  第16回分子科学討論会
- Data Source
  KAKENHI-PROJECT-22K05027
[Presentation] 蛍光タンパク質の蛍光寿命の制御2019
- Author(s)
  坪田空樹, 間紗希子, 山口佳那子, 宮武秀行, 内田朗, 細井晴子
- Organizer
  分子科学討論会
- Data Source
  KAKENHI-PROJECT-17K05764
[Presentation] 蛍光タンパク質eYFPとそのY145変異体の蛍光寿命に与える発色団周辺環境の影響2017
- Author(s)
  間紗希子・宮武秀行・内田朗・細井晴子
- Organizer
  第11回分子科学討論会
- Data Source
  KAKENHI-PROJECT-17K05764
[Presentation] 超高速時間分解分光法による蛍光タンパク質の発光メカニズムの研究2017
- Author(s)
  細井晴子
- Organizer
  生物発光化学発光研究会　第33回学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17K05764
[Presentation] Smaller 145th Residue Makes Fluorescent Protein Non-Fluorescent:Fluorescence Lifetimes of Enhanced Yellow Fluorescent Protein (eYFP) Y145 Mutants and H148 Mutants2015
- Author(s)
  Haruko Hosoi
- Organizer
  National Symposium on Radiation and Photochemistry
- Place of Presentation
  Indian Institute of Technology Kanpur, India
- Year and Date
  2015-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-24550033
[Presentation] GFP発色団モデル化合物における二光子吸収スペクトルの溶媒依存性2011
- Author(s)
  田山亮、竹内佐年、水野秀昭、宮脇敦史、田原太平、細井晴子
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] GFP発色団モデル化合物における二光子吸収スペクトルの溶媒依存性2011
- Author(s)
  細井晴子、田山亮、竹内佐年、水野秀昭、宮脇敦史、田原太平
- Organizer
  第5回分子科学討論会
- Place of Presentation
  第5回分子科学討論会、札幌コンベンションセンター(札幌市)
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] Physisorption gives narrower orientational distribution than chemisorption a glass surface : A polarization-sensitive linear and nonlinear optical study2010
- Author(s)
  山口祥一、細井晴子、山下めぐみ、Pratik Sen、田原太平
- Organizer
  第26回化学反応討論会
- Place of Presentation
  広島県東広島市
- Year and Date
  2010-06-02
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] ペプチドヘリックスの配向を調べるための新しい架橋型色素の合成と性質2010
- Author(s)
  上村康裕, 山下めぐみ, 山口祥一, 田原太平, 細井晴子, 渡邊総一郎
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学、東大阪市
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] ヘテロダイン電子和周波発生分光法を用いたタンパク質トポロジー決定法の開発2010
- Author(s)
  細井晴子・山口祥一・田林沙織・双木泰斗・上村康裕・渡邊総一郎・清水啓史・田原太平
- Organizer
  第4回分子科学討論会
- Place of Presentation
  大阪府豊中市
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] ヘテロダイン電子和周波発生(HD-ESFG)分光法の膜タンパク質トポロジー決定への適用2009
- Author(s)
  細井晴子、山口祥一、二本柳聡史、田原太平
- Organizer
  シンポジウム「表面・界面を観る非線形分光の新しい展開」
- Place of Presentation
  和光
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] ヘテロダイン検出二次非線形分光法の膜タンパク質トポロジー決定への適用2009
- Author(s)
  細井晴子
- Organizer
  第7回ミニ公開シンポジウム「イオンチャネルの構造ダイナミクスII」
- Place of Presentation
  越前町生涯学習センター越前分館、福井県
- Year and Date
  2009-09-01
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] Hidden electronic excited state of enhanced green fluorescent protein by multiplex two-photon absorption spectroscopy2008
- Author(s)
  H. Hosoi, S. Yamaguchi, H. Mizuno, A. Miyawaki and T. Tahara
- Organizer
  The 235^<th> ACS National Meeting
- Place of Presentation
  New Orleans LA, USA
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] カルシウムセンサー蛍光タンパク質cameleonの共鳴エネルギー移動効率の不均一性2008
- Author(s)
  石井邦彦、細井晴子、水野秀昭、宮脇敦史、田原太平
- Organizer
  第2回分子科学討論会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] Hidden electronic excited state of enhanced green fluorescence protein (eGFP) by new multiplex two-photon absorption spectroscopy2008
- Author(s)
  H. Hosoi, S. Yamaguchi, H. Mizuno, A. Miyawaki and T. Tahara
- Organizer
  Tokyo International Symposium on Time-and Space-resolved Vibrational Spectroscopy
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] ポリアクリルアミド系ナノ微粒子の溶媒和構造2007
- Author(s)
  藤野竜也、細井晴子、南條大輔、田原太平、伊永隆史
- Organizer
  日本化学会第1回関東支部大会
- Place of Presentation
  八王子
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] Ultrafat solvation dynamics of hydrophilic polymer fine particles2007
- Author(s)
  T. Fujino, H. Hosoi, D. Nanjo, T. Tahara, and T. Korenaga
- Organizer
  XXIII International Conference on Photochemistry
- Place of Presentation
  Cologne, Germany
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] 蛍光タンパク質eGFPの‘隠れた'電子励起状態:マルチプレックス二光子吸収およびフェムト秒時間分解蛍光法による追跡2007
- Author(s)
  細井晴子、山口祥一、水野秀昭、宮脇敦史、田原太平
- Organizer
  第1回分子科学討論会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] 高分子ナノ微粒子のフェムト秒時間分解蛍光分光2007
- Author(s)
  藤野竜也、細井晴子、南條大輔、田原太平、伊永隆史
- Organizer
  分析化学討論会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PLANNED-19056009
[Presentation] 蛍光タンパク質eYFPの蛍光寿命を決定する145番アミノ酸側鎖の性質
- Author(s)
  細井　晴子・間　紗希子・石野　佳奈・山畔　麻優
- Organizer
  日本化学会第94春季年会(2014)
- Place of Presentation
  名古屋大学東山キャンパス(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-24550033
[Presentation] 蛍光タンパク質の隠れた電子励起状態
- Author(s)
  細井晴子
- Organizer
  特定領域研究「分子高次系機能解明のための分子科学－先端計測法の開拓による素過程的理解」成果公開シンポジウム
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-24550033

1. YAMAGUCHI Shoichi (60250239)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. TAHARA Tahei (60217164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
3. TAKEUCHI Satoshi (50280582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. ISHII Kunihiko (80391853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MORITA Akihiro (70252418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ASANO Motoko (80201888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 宮武秀行 (50291935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 内田朗 (30176680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Hosoi Haruko 細井 晴子

細井 晴子 ホソイ ハルコ

HOSOI Haruko 細井 晴子

Research Projects

Research Products

Co-Researchers

Dynamic higher-order conformational changes control the fluorescence lifetime of fluorescent proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Correlation between the fluorescence lifetime and the local environment of the chromophore: Universal nature to fluorescent proteins from the jellyfish Aequorea VictoriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hidden electronic excited state of enhanced green fluorescent proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein Structure Analysis by Second-order Nonlinear Spectroscopy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of complex molecular systems by advanced molecular spectroscopy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 月刊「細胞」2023年 4月臨時増刊号 蛍光タンパク質センサー （蛍光タンパク質の機能と構造不均一性の関係）2023

Author(s)

Total Pages

Publisher

Data Source

[Book] "二光子吸収材料の非線形光学スペクトル測定"高効率二光子吸収材料の開発と応用2011

Author(s)

Publisher

Data Source

[Journal Article] Diverse Fluorescence Resonance Energy Transfer Processes Originating from the Conformational Heterogeneity of the Calcium Indicator Yellow Cameleon YC3.602023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Solvent Dependence of Two-photon Absorption Spectra of the Enhanced Green Fluorescent Protein (eGFP) Chromophore2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Smaller 145th Residue Makes Fluorescent Protein Non-Fluorescent: Fluorescence Lifetimes of Enhanced Yellow Fluorescent Protein (eYFP) Y145 Mutants and H148 Mutants2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physisorption gives narrower orientational fistribution than chemisorption on a glass surface : A polarization-sensitive linear and nonlinear optical study2010

Author(s)

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[Journal Article] Physisorption Gives Narrower Orientational Distribution than Chemisorption on a Glass Surface: A Polarization-Sensitive Linear and Nonlinear Optical Study2010

Author(s)

Journal Title

Data Source

[Journal Article] Physisorption gives narrower orientational distribution than chemisorption on a glass surface: A polarization-sensitive linear and nonlinear optical study2010

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[Journal Article] 超短パルスレーザーを用いた先端的分光計測による蛍光タンパク質の発光機構の研究2009

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NAID

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[Journal Article] Picosecond time-resolved fluorescence study of poly vinyl methylether aqueous solution2009

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Hosoi Haruko 細井晴子

細井晴子ホソイハルコ

HOSOI Haruko 細井晴子

[Book] 月刊「細胞」2023年 4月臨時増刊号　蛍光タンパク質センサー　（蛍光タンパク質の機能と構造不均一性の関係）2023