Sakaguchi Kazuyasu 坂口和靖

… Alternative Names

Researcher Number	00315053
Other IDs
Affiliation (Current)	2020: 北海道大学, 理学研究院, 教授
Affiliation (based on the past Project Information) *help	2019 – 2020: 北海道大学, 理学研究院, 教授 2016: 北海道大学, 理学研究院, 教授 2011 – 2015: 北海道大学, 理学(系)研究科(研究院), 教授 2014: 北海道大学, 大学院理学研究院, 教授 2007 – 2012: Hokkaido University, 大学院・理学研究院, 教授 … More
Review Section/Research Field	Principal Investigator Living organism molecular science / Biological Sciences / Bioorganic chemistry / Science and Engineering / Biomolecular chemistry / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 37030:Chemical biology-related Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator ペプチド / 脱リン酸化 / 蛋白質 / ホスファターゼ / リン酸化 / 癌抑制タンパク質 / 生体分子 / 細胞周期 / 抗体 / 翻訳後修飾 … More Except Principal Investigator ホスファターゼ / 酵素 / 染色体不安定性 / がん Less

Development of a novel genome editing method through transient arrest control of the tumor suppressor protein p53Principal InvestigatorOngoing
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Hokkaido University
細菌リボソームRNAにコードされ生存危機ストレスにより翻訳される防御ポリペプチドPrincipal InvestigatorOngoing
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Hokkaido University
Development of a new method for identifying substrates of PPM1 phosphatase familyPrincipal Investigator
- Principal Investigator
  
  Sakaguchi Kazuyasu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
Control of Bioreaction via Oligomerization and Orientation of Tumor Suppressor Protein p53 TetramerPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Study on the molecular mechanism of genome instability in the cells with overexpression of PPM1D
- Principal Investigator
  
  CHUMAN Yoshiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Niigata University
  Hokkaido University
Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerizationPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Stability Change of Tetrameric Structure of Tumor Suppressor Protein p53 in Mutation and Evolution, and Threshold for Loss of Tumor Suppressor Activity in Terms of Disruption of the Tetrameric Structure.Principal Investigator
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
E‐Life構築を目指したD型タンパク質翻訳系の開発Principal Investigator
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Inactivation of Tumor Suppressor Protein p53 by Mutations in the Tetramerization Domain and Stabilizing Methods for the Tetrameric StructurePrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
がん抑制タンパク質p53の四量体形成ドメインのフォールディングPrincipal Investigator
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
酸化ストレス解析のための特異的モノクローナル抗体作製法の開発Principal Investigator
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Design and development of tumor suppressor protein p53 variant that cannot form heterooligomers with the wild-type proteinPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
  Kyushu University
p53誘導性ホスファターゼWip1の局在化とSH3蛋白質を介した細胞周期の制御Principal Investigator
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
p53誘導性ホスファターゼWip1の局在化調節を介した細胞周期の制御機構の解明Principal Investigator
- Principal Investigator
  
  坂口和靖
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Method for Protein Phosphorylation Analysis by Use of Antibodies Specific to Phosphorylation MotifsPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYUSHU UNIVERSITY

[Journal Article] Methylation of the Tetramerization Domain in Tumor Suppressor Protein p53 by PRMT52015
- Author(s)
  N. Nakagawa, J. Wada, R. Kamada, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2014 Pages: 183-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] Synthesis of Yellow and Red Fluorescent 1,3a,6a-Triazapentalene and Theoretical Investigation of Optical Properties.2015
- Author(s)
  Kosuke Namba, Ayumi Osawa, Akira Nakayama, Akane Mera, Fumi Tano, Yoshiro Chuman, Eri Sakuda, Tetsuya Taketsugu, Kazuyasu Sakaguchi, Noboru Kitamura, Keiji Tanino
- Journal Title
  
  Chem. Sci.
  
  Volume: 6 Pages: 83-109
- DOI
  10.1039/c4sc02780a
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J02457, KAKENHI-PROJECT-23750141, KAKENHI-PROJECT-24310162, KAKENHI-PROJECT-24570146, KAKENHI-PROJECT-26560449, KAKENHI-PROJECT-15K05560, KAKENHI-PROJECT-15K06563, KAKENHI-PLANNED-15H05842, KAKENHI-PUBLICLY-26102734, KAKENHI-PUBLICLY-26110501, KAKENHI-PROJECT-15H03806
[Journal Article] Antiproliferative Activity of Silver Nanoplates on Human Promyelocytic Leukemia Cell Lines2015
- Author(s)
  Sakaguchi T., Mine K., Kudoh F., Kamada R., Sakaguchi K.
- Journal Title
  
  Chemistry Letters
  
  Volume: 44 Issue: 3 Pages: 327-329
- DOI
  10.1246/cl.141085
- NAID
  130004868407
- ISSN
  0366-7022, 1348-0715
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J02657, KAKENHI-PROJECT-24310152
[Journal Article] Quantitative Analysis of p53 Hetero-tetramers for Dominant Negative Effect in Transcriptional Activity2015
- Author(s)
  Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2014 Pages: 181-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] Effects of Biomineralization Peptide Topology on the Structure and Catalytic Activity of Pd Nanomaterials2014
- Author(s)
  Janairo J.I., Sakaguhi T., Hara K., Fukuoka A., Sakaguchi K.
- Journal Title
  
  CHEMICAL COMMUNICATIONS
  
  Volume: 50 Pages: 9259-9262
- DOI
  10.1039/c4cc04350b
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J02657, KAKENHI-PROJECT-24310152, KAKENHI-PUBLICLY-25105703, KAKENHI-PLANNED-25106010
[Journal Article] Effects of Buffer on the Structure and Catalytic Activity of Palladium Nanomaterials Formed by Biomineralization2014
- Author(s)
  J. I. B. Janairo and K. Sakaguchi
- Journal Title
  
  Chemistry Letters
  
  Volume: 43 Issue: 8 Pages: 1315-1317
- DOI
  10.1246/cl.140405
- NAID
  130004427156
- ISSN
  0366-7022, 1348-0715
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] Silver nanocrystals formed by oligemeric biomineralization peptide via p53 tetramerization domain.2013
- Author(s)
  T. Sakaguchi, J. I. Janairo, Y. Chuman, K. Hara, A. Fukuoka, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2012 Pages: 57-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651210
[Journal Article] Silver nanocrystals formed by oligemeric biomineralization peptide via p53 tetramerization domain2013
- Author(s)
  T. Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: 2012 Pages: 57-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] Effects of <i>E</i>/<i>Z</i> Configuration of Fluoroalkene-containing HDAC Inhibitors on Selectivity for HDAC Isoforms2013
- Author(s)
  Yoshiro Chuman, Mariko Ueyama, Satoshi Sano, Fei Wu, Yuhei Kiyota, Takayoshi Higashi, Satoshi Osada, and Kazuyasu Sakaguchi
- Journal Title
  
  Chemistry Letters
  
  Volume: 42 Issue: 8 Pages: 833-835
- DOI
  10.1246/cl.130243
- NAID
  10031189265
- ISSN
  0366-7022, 1348-0715
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152, KAKENHI-PROJECT-24570146
[Journal Article] Formation of Functionalized Nanowires Based on Control of Self-Assembly Using Multiple Modified Amyloid Peptides2013
- Author(s)
  Hiroki Sakai, Ken Watanabe, Yuya Asanomi, Yumiko Kobayashi, Yoshiro Chuman, Lihong Shi, Takuya Masuda, Thomas Wyttenbach, Michael T. Bowers, Kohei Uosaki, and Kazuyasu Sakaguchi
- Journal Title
  
  Adv. Funct. Mater.
  
  Volume: 23 Pages: 4881-4887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] アミロイドペプチドの自己組織化制御による機能化ナノワイヤー形成2013
- Author(s)
  坂井公紀、坂口和靖
- Journal Title
  
  機能材料
  
  Volume: 33 Pages: 47-53
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] Formation of Functionalized Nanowires by Control of Self-Assembly Using Multiple Modified Amyloid Peptides.2013
- Author(s)
  Sakai H, Watanabe K, Asanomi Y, Kobayashi Y, Chuman Y, Shi L, Masuda T, Wyttenbach T, Bowers MT, Uosaki K, Sakaguchi K
- Journal Title
  
  Adv. Funct. Mater.
  
  Volume: 23 Pages: 4881-4887
- DOI
  10.1002/adfm.201300577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07100, KAKENHI-PROJECT-24570146
[Journal Article] Silver nanocrystals formed by oligemeric biomineralization peptide via p53 tetramerization domain2013
- Author(s)
  T. Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: 2012 Pages: 57-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651210
[Journal Article] A Small Molecule Inhibitor of p53-inducible Protein Phosphatase PPMID2012
- Author(s)
  八木寛陽
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: VOL.22 Pages: 729-732
- DOI
  10.1016/j.bmcl.2011.10.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01998, KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-22710206, KAKENHI-PROJECT-23651210, KAKENHI-PROJECT-24350018, KAKENHI-PROJECT-24570146, KAKENHI-PLANNED-21106010
[Journal Article] Repression of p53transcriptional activity by inhibitory peptide via heterotetramerization2012
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 301-302
- NAID
  10030204437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Nanostructure formed bybiomineralization peptide oligomerized via p53 tetramerization2012
- Author(s)
  T. Sakaguchi, R. Kamada, Y. Chuman, andK. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 345-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651210
[Journal Article] Development of screening system for tumor suppressor p53 activators and inhibitors2012
- Author(s)
  K. Uesugi, S. Oshima, A. Tanaka, T.Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 403-404
- NAID
  10030204653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651210
[Journal Article] Repression of p53 transcriptional activity by inhibitory peptide via heterotetramerization2012
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T.Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 301-302
- NAID
  10030204437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651210
[Journal Article] Development of screening system for tumor suppressor p53 activators and inhibitors2012
- Author(s)
  K. Uesugi, S. Ohshima, A. Tanaka, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 345-346
- NAID
  10030204653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerization2012
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Bioorg Med Chem. Lett.
  
  Volume: 22 Pages: 2780-2783
- DOI
  10.1016/j.bmcl.2012.02.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-23651210
[Journal Article] Nanostructure formed by biomineralization peptide oligomerized via p53 tetramerization2012
- Author(s)
  T.Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: 2011 Pages: 345-346
- NAID
  10030204547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Nanostructure formed by biomineralization peptide oligomerized via p53 tetramerization2012
- Author(s)
  T. Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: 2011 Pages: 345-346
- NAID
  10030204547
- Data Source
  KAKENHI-PROJECT-23651210
[Journal Article] Nanostructure formed by biomineralization peptide oligomerized via p53 tetramerization2012
- Author(s)
  T. Sakaguchi, R. Kamada, Y. Chuman, and K.Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 345-346
- NAID
  10030204547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Effect of Peptide Oligomerization Mediated by p53 Tetramerization Domain on Biomineralization Activity.2011
- Author(s)
  T.Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: (in press,in press)
- NAID
  10028238136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21651088
[Journal Article] Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine2011
- Author(s)
  T. Nomura, R. Kamada, I. Ito, K. Sakamoto, Y. Chuman, K. Ishimori, Y. Shimohigashi, and K. Sakaguchi
- Journal Title
  
  Biopolymers
  
  Volume: 95 Pages: 410-419
- DOI
  10.1002/bip.21594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-22221005
[Journal Article] Formation process and solvent-dependent structure of a polyproline self-assembled monolayer on a gold surface.2011
- Author(s)
  Y.Han
- Journal Title
  
  Langmuir
  
  Volume: 27 Pages: 11951-11957
- DOI
  10.1021/la2020995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-23651210
[Journal Article] Cancer-associated p53 Tetramerization Domain Mutants Quantitative Analysis Reveals a Low Threshold for Tumor Suppressor Inactivation2011
- Author(s)
  R. Kamada, T. Nomura, C. W. Anderson, and K. Sakaguchi
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 252-258
- DOI
  10.1074/jbc.m110.174698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Effect of Peptide Oligomerization Mediated by p53 Tetramerization Domain on Biomineralization Activity2011
- Author(s)
  T. Sakaguchi, R. Kamada, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2010 Pages: 269-270
- NAID
  10028238136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Low Threshold of Destabilization for Loss of Tumor Suppressor Activity of p53 : A Quantitative Analysis of p53 Tetramerization Domain Mutants2011
- Author(s)
  R. Kamada, T. Nomura, Y. Chuman, T.Imagawa C.W. Anderson, and K. Sakaguchi
- Journal Title
  
  Peptide Sci
  
  Volume: 2010 Pages: 149-150
- NAID
  10028237634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Repression of p53 transcriptional activity by p53 tetramerization domain peptide containing PTD and NLS domain2011
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2010 Pages: 95-96
- NAID
  10028237399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Effect of Peptide Oligomerization Mediated by p53 Tetramerization Domain on Biomineralization Activity.2011
- Author(s)
  T.Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: in press
- NAID
  10028238136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Biomineralization Activity of Multivalent min TBP-1 Peptide Mediated by p53 Tetramerization Domain2010
- Author(s)
  T. Sakaguchi, R. Kamada, T. Nomura, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2009 Pages: 411-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Biomineralization Activity of Multivalent minTBP-1 Peptide Mediated by p53 Tetramerization Domain.2010
- Author(s)
  T.Sakaguchi
- Journal Title
  
  Peptide Science
  
  Volume: 2009 Pages: 411-412
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Inhibition of p53 by Introducing Tetramerization Domain Peptide Fused with Polyvalent Cationic Sequence into cells2010
- Author(s)
  R. Kamada, S. Ohshima, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2009 Pages: 319-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Tetramerization of tumor suppressor protein p532010
- Author(s)
  R. Kamada and K. Sakaguchi
- Journal Title
  
  Seikagaku
  
  Volume: 82 Pages: 848-93
- NAID
  10026899887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Biomineralization Activity of Multivalent minTBP-1 Peptide Mediated by p53 Tetramerization Domain.2010
- Author(s)
  T.Sakaguchi
- Journal Title
  
  Peptide Science 2009
  
  Pages: 411-412
- Data Source
  KAKENHI-PROJECT-21651088
[Journal Article] Effects of tumor-associated mutations in the p53 tetramerization domain on oligomerization state and transcriptional activity2009
- Author(s)
  R. Kamada, T. Terai, T. Nomura, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 611 Pages: 567-8
- DOI
  10.1007/978-0-387-73657-0_249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Effects of tumor-associated mutations in thep53 tetramerization domain onoligomerization state and transcriptionalactivity2009
- Author(s)
  R. Kamada, T. Terai, T. Nomura, Y. Chuman, T. Imagawa, K. Sakaguchi
- Journal Title
  
  Adv. Exp.Med. Biol 611
  
  Pages: 567-568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Evaluation of Transcriptional Activity of p53 in Individual Living Mammalian Cell2009
- Author(s)
  T.Imagawa, T. Terai, Y. Yamada, R. Kamada and K. Sakaguchi
- Journal Title
  
  Anal. Biochem. 387
  
  Pages: 249-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Characterization of a new cancer-associated mutant of p53 with a missense mutation(K351N) in the tetramerization domain2009
- Author(s)
  M. Muscolini, E. Montagni, S. Caristi, T.Nomura, R. Kamada, S. Di Agostino, M. Corazzaari, M. Piacentini, G. Blandino, A. Costanzo, K. Sakaguchi, and L. Tuosto
- Journal Title
  
  Cell Cycle
  
  Volume: 8 Pages: 3396-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Thermal Stability of p53 Tetramerization Domain Peptides Derived from Various Species2009
- Author(s)
  T. Nomura, R. Kamada, Y. Chumanand and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2008
  
  Pages: 35-36
- NAID
  10027165876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure2009
- Author(s)
  T. Nomura, R. Kamada, I. Ito, Y.Chuman, Y. Shimohigashi, K. Sakaguchi
- Journal Title
  
  Biopolymers 91(1)
  
  Pages: 78-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Correlation of Oligomeric Structure and Transcriptional Activity of p53 Mutants2008
- Author(s)
  R. Kamada, T. Terai, T. Nomura, Y. Chuman, T.Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 69-70
- NAID
  10021906623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Correlation of Oligomeric Structure and Transcriptional Activity of p53 Mutants2008
- Author(s)
  K. Sakaguchi
- Journal Title
  
  Peptide Science 2007
  
  Pages: 69-70
- NAID
  10021906623
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Correlation between Expression Level in E.coli and Stability of Oligomeric Structure ofthe p53 Tetramerization Domain2008
- Author(s)
  H. Miyazaki, R. Kamada, T. Nomura, Y. Chuman, T.Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 317-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Differential Recognition of PhosphorylatedTransactivation Domains of p53 by Differentp300 Domains2008
- Author(s)
  S. Polley, S. Guha, N.S. Roy,S. Kar, K. Sakaguchi, Y. Chuman, V.Swaminathan and S. Roy
- Journal Title
  
  J. Mol. Biol. 376
  
  Pages: 8-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Structural Photomodulation of Peptides with Azobenzoate Derivative in Peptide Backbone.2008
- Author(s)
  R. Kamada, K. Fukuda, H. Miyazaki, T.Nomura, Y. Chuman, T. Imagawa, K. Tanino and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 447-448
- NAID
  10021907298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Screening of Peptides to Stabilize the p53 Tetramer Formation from Phage Displayed Library2008
- Author(s)
  T. Nomura, R. Kamada, Y. Chuman and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 315-316
- NAID
  10021907074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Thermodynamic Stability of Mutant p53 Tetramerization Domain Peptides Associated with Human Tumors2007
- Author(s)
  R. Kamada, T. Nomura, Y. chuman, T. Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2006
  
  Pages: 131-132
- NAID
  10020530042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Stabilization of p53 Tetrameric Structure by Polyol Compounds2007
- Author(s)
  T. Nomura, Y. Chuman and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2006
  
  Pages: 131-132
- NAID
  10020529267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Fibrillar and Granular Aggregation of G334V Mutant p53 Tetramer Peptide. Y. Asanomi, Y. Higashimoto2006
- Author(s)
  Y. Asanomi, Y. Higashimoto, Y. Chuman, S. Kaya, T. Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2005
  
  Pages: 397-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Unfolding, Aggregation, and Amyloid Formation by the Tetramerization Domain from Mutant p53 Associated with Lung Cancer2006
- Author(s)
  Y. Higashimoto, Y. Asanomi, S.Takakusagi, M. S. Lewis, K. Uosaki, S. R. Durell, C. W. Anderson, E. Appella and K. Sakaguchi
- Journal Title
  
  Biochemistry 45
  
  Pages: 1608-1619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Analysis of Stabilization by Substituti on of Cyclohexylalanine for Phe341 in Hydrophobic Core of p53 Tetramer.2006
- Author(s)
  T. Nomura, K. Sakamoto, Y. Kasai, Y. Chuman, K. Ishimori and K. Sakaguchi
- Journal Title
  
  Peptide Science 2005
  
  Pages: 399-402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Effects of mutation and modification on tetramer formation of tumor suppressor protein p53.2005
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2004
  
  Pages: 17-20
- NAID
  10014459478
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380290
[Journal Article] Hetero-Oligomer Formation of Peptides Derived from Tetramerization Domain in Tumor Suppressor Protein p532004
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2003
  
  Pages: 307-310
- NAID
  10012654299
- Data Source
  KAKENHI-PROJECT-16041202
[Journal Article] Hetero-Oligomer Formation of Peptides Derived from Tetramerization Domain in Tumor Suppressor Protein p532004
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2003
  
  Pages: 307-310
- NAID
  10012654299
- Data Source
  KAKENHI-PROJECT-15651100
[Journal Article] Hetero-Oligomer Formation of Peptides Derived from Tetramerization Domain in Tumor Suppressor Protein p532004
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2003
  
  Pages: 307-310
- NAID
  10012654299
- Data Source
  KAKENHI-PROJECT-14380290
[Journal Article] Hetero-oligomer formation of peptides derived from tetramerization domain in tumor suppressor protein p53.2004
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2003
  
  Pages: 307-310
- NAID
  10012654299
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380290
[Journal Article] Phosphorylation site-specific monoclonal antibody recognizing Ser(P)-Gln sequence.2003
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2002
  
  Pages: 439-442
- NAID
  80015936244
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380290
[Journal Article] Phosphorylation site-specific monoclonal antibody recognizing Ser(P)-Gin sequence.2003
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2002
  
  Pages: 439-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380290
[Journal Article] Structural characterization of Phe residues in the p53 tetramerization domain.2002
- Author(s)
  Sakaguchi, K.
- Journal Title
  
  Peptide Science 2001
  
  Pages: 135-138
- NAID
  10009660305
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380290
[Patent] プロテインホスファターゼ阻害剤2008
- Inventor(s)
  坂口和靖, 谷野圭持, 中馬吉郎, 吉村文彦, 八木寛陽
- Industrial Property Number
  2008-262646
- Filing Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-18310140
[Patent] p53翻訳後修飾部位を特異的に認識するーナル抗体、及びその抗体を含む修飾部位測定キット2006
- Inventor(s)
  坂口和靖, 中馬吉郎, 明日山康生, 松木園美穂
- Industrial Property Number
  2007-511193
- Filing Date
  2006-03-31
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] p53-inducible phosphatase PPM1D: Function, regulation and inhibitor deveolment2016
- Author(s)
  Kazuyasu Sakaguchi
- Organizer
  16th Akabori Conference
- Place of Presentation
  六甲山ホテル（兵庫県・神戸市）
- Year and Date
  2016-05-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] 多様なシグナル経路に関与するPPM1Aホスファターゼの脱リン酸化部位認識機構2016
- Author(s)
  白幡祐貴子、清田雄平、松山祐昂、西村裕一、中馬吉郎、下東康幸、坂口和靖
- Organizer
  日本化学会秋季事業第6回CSJフェスタ2016
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] 脂肪細胞におけるp53誘導性ホスファターゼPPM1D阻害剤の脂肪滴形成抑制効果2016
- Author(s)
  鎌田瑠泉、木村望、小笠原紗里、工藤風樹、清田雄平、坂口和靖
- Organizer
  第７回プロテインホスファターゼ研究会
- Place of Presentation
  基礎生物学研究所（愛知県・岡崎市）
- Year and Date
  2016-01-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] Ser/ThrホスファターゼPPM1A（PP2C-a）の脱リン酸化部位認識機構2016
- Author(s)
  白幡祐貴子、清田雄平、松山祐昂、鎌田瑠泉、下東康幸、坂口和靖
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] Regulation of adipocyte differentiation and lipid droplet formation by PPM1D phosphatase2016
- Author(s)
  Kazuyasu Sakaguchi
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府・東大阪市）
- Year and Date
  2016-10-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] リン脂質のPPM1ホスファターゼILKAP脱リン酸化活性に対する効果2016
- Author(s)
  塚原七星,清田雄平,白幡祐貴子,鎌田瑠泉,坂口和靖
- Organizer
  第７回プロテインホスファターゼ研究会
- Place of Presentation
  基礎生物学研究所（愛知県・岡崎市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] Tetramerization Domain of Tumor Suppressor Protein p53: Evolution, Mutation and Application2015
- Author(s)
  Kazuyasu Sakaguchi
- Organizer
  7th International Peptide Symposium
- Place of Presentation
  Biopolis (Singapore)
- Year and Date
  2015-12-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] PPM1ホスファターゼILKAPの脱リン酸化能に対するリン脂質の効果2015
- Author(s)
  塚原七星、清田雄平、白幡祐貴子、鎌田瑠泉、坂口和靖
- Organizer
  第５回CSJフェスタ2015
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] PPM1Dホスファターゼ阻害剤の急性前骨髄球性白血病細胞株HL-60分化に対する効果2015
- Author(s)
  工藤風樹、鎌田瑠泉、吉村文彦、谷野圭持、坂口和靖
- Organizer
  第52回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学（北海道・札幌市
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] Analysis of Stability of Tetrameric Structure and Transcriptional Activity in Evolution of Tumor Suppressor Protein p532015
- Author(s)
  J. Wada and K. Sakaguchi
- Organizer
  U de M HU Joint Graduate Student Symposium
- Place of Presentation
  Universite of Montreal（Canada）
- Year and Date
  2015-02-05
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] 多量体化と配向化を基盤としたバイオミネラリゼーションによる銀ナノ構造体の構造制御2015
- Author(s)
  T. Sakaguchi and K. Sakaguchi
- Organizer
  the Poster Session for 5th Anniversary of Foundation CSE
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Oncogenic phosphatase PPM1D: Role in carcinogenesis and its inhibitors2015
- Author(s)
  坂口和靖
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートピアホテル（兵庫県・神戸市）
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-15K12738
[Presentation] Re-evaluation the Transcriptional Activity of p53 Hetero-tetramers for Dominant Negative Effect2014
- Author(s)
  Y. Toguchi, M. Kanno, T. Imagawa and K. Sakaguchi
- Organizer
  2nd Intennational Symposium on Ambitious Leader's Program
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Novel Fluorescent Probe TAP-4PH for Cytoplasmic Staining in Living Cell2014
- Author(s)
  F. Kudoh, F. Tano, A. Osawa, R. Kamada, Y. Chuman, K. Namba, K. Tanino, and K. Sakaguchi
- Organizer
  Frontiers in Chemical Sciences 2014 (SNU-HU)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] ヒトPPM1Dホスファターゼによる染色体不安定化と新規発がん機構2014
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、梨本健紘、水上洋平、今川敏明、坂口和靖
- Organizer
  第55回新潟生化学懇話会
- Place of Presentation
  長岡技術科学大学(長岡市）
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Control of Silver Nanoparticle Formation by Oligomerization and Orientation of Biomineralization Peptide2014
- Author(s)
  T. Sakaguchi
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学（名古屋市）
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Tetramer Formation of Tumor Suppressor Protein p53: Tumorigenesis and Evolution2014
- Author(s)
  K. Sakaguchi
- Organizer
  Frontiers in Chemical Sciences 2014 (SNU-HU)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] p53ヘテロ多量体形成および転写活性化能の細胞内定量的解析系の構築2014
- Author(s)
  菅野まどか、今川敏明、戸口侑、鎌田瑠泉、坂口和靖
- Organizer
  日本生化学会北海道支部第51回支部例会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] 17q23にコードされたPPM1Dホスファターゼ過剰発現による染色体不安定化2013
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、梨本健紘、水上洋平、今川敏明、坂口和靖
- Organizer
  第50回日本生化学会北海道支部会
- Place of Presentation
  北海道大学医学部フラテ会館
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Recognition of Phosphorylated Ser/Thr residues by Human PPM1 Family Phosphatases2013
- Author(s)
  Yoshiro Chuman, Yukiko Shirahata, Yuhei Kiyota, Ryo Iwamuro, Jose Isagani B. Janairo, Hiroaki Yagi, and Kazuyasu Sakaguchi
- Organizer
  10th International Conference on Protein Phosphatase
- Place of Presentation
  国立がんセンター（東京都）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Functionalized Nanowire Formation via Control of Self-Assembly Using Multiple Modified Amyloid Peptides2013
- Author(s)
  K. Sakaguchi
- Organizer
  The 9th Nanjin-Hokkaid-NIMS/MANA Joint Symposium
- Place of Presentation
  南京（中国）
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Development of New Nanostructure Control Method via Oligomerization of Biomineralization Peptide2013
- Author(s)
  T. Sakaguchi
- Organizer
  Frontier Chemistry Center The 2nd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] p53四量体形成ドメインを介したバイオミネラリゼーションベプチドの立配置による銀ナノ結晶形成2013
- Author(s)
  T. Sakaguchi
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学(草津市)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] p53誘導性ホスファターゼPPM1D過剰発現による染色体不安定性機構2013
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、梨本健紘、水上洋平、今川敏明、坂口和靖
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Structure Control of Silver Nanoparticles by Orientation Control of Biomineralization Peptides using Oligomerization Peptides2013
- Author(s)
  T. Sakaguchi
- Organizer
  The 9th Nanjin-Hokkaid-NIMS/MANA Joint Symposium
- Place of Presentation
  南京（中国）
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] アミロイドペプチドの自己組織化制御による機能性ナノワイヤー形成2013
- Author(s)
  坂口和靖
- Organizer
  2013年真空・表面学術合同講演会：第33回表面科学学術講演会・第54回真空に関する連合講演会
- Place of Presentation
  つくば国際会議場（つくば市）
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Structure Stability of the Tetramerization Domain of Tumor Suppressor Protein p532013
- Author(s)
  K. Sakaguchi
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館（鳥取市）
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Formation of Functionalized Nanowires via Control of Self-Assembly Using Multiple Modified Amyloid Peptides2013
- Author(s)
  K. Sakaguchi
- Organizer
  ４th Asia Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク（大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Expression of p53-inducible Protein phosphatase PPM1D in Pluripotent Human Germ Cell Tumor-derived Cell Line, NCCIT2012
- Author(s)
  Yoshiro Chuman, Takahiro Michiba, Kazuyasu Sakaguchi
- Organizer
  The 58th/60th NIBB Conference “Germline -Specification, Sex, and Stem Cells-“
- Place of Presentation
  岡崎カンファレンスセンター（愛知県）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Silver Nanoparticle Formation by Oligomeric Biomineralization Peptide via p53 Tetramerization Domain2012
- Author(s)
  T. Sakaguchi
- Organizer
  2012 HU-NU-SNU-NIMS/MANA Joint Symposium
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] p53四量体形成ドメインを介した多量体バイオミネラリゼーションペプチドによる銀粒子形成2012
- Author(s)
  T.Sakaguchi
- Organizer
  第92日本化学会春季年会
- Place of Presentation
  慶應義塾大学(横浜市)
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Biomineralization and nanoparticle arrangement by Oligomeric Peptides2012
- Author(s)
  K. Sakaguchi
- Organizer
  Cambodian Malaysian Chemical Conference 2012
- Place of Presentation
  Angkor Century Resort and Spa (カンボジア)
- Invited
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] ヒトPPM1ホスファターゼにおけるリン酸化アミノ酸選択性2012
- Author(s)
  中馬吉郎・岩室良・白幡祐貴子・Jose Isagani B. Janairo・清田雄平・八木寛陽・坂口和靖
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] p53四量体形成ドメインを介した多量体バイオミネラリゼーションペプチドによる銀粒子形成2012
- Author(s)
  T.Sakaguchi
- Organizer
  第92日本化学会春季年会
- Place of Presentation
  慶應義塾大学(横浜市)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Control of Biomineralization and Nanoparticle Arrangement via Peptide Self-assembly2012
- Author(s)
  K. Sakaguchi
- Organizer
  14th Akabori Conference
- Place of Presentation
  ニセコ町民センター(北海道)(招待講演)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Control of Biomineralization and Nanoparticle Arrangement via Peptide Self-assembly2012
- Author(s)
  K. Sakaguchi
- Organizer
  14th Akabori Conference
- Place of Presentation
  ニセコ町民センター(北海道)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] p53四量体形成ドメインを介した多量体バイオミネラリゼーションペプチドによる銀粒子形成2012
- Author(s)
  T. Sakaguchi
- Organizer
  第92日本化学会春季年会
- Place of Presentation
  慶應義塾大学（横浜市）
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Control of Biomineralization and Nanoparticle Arrangement via Peptide Self-assembly2012
- Author(s)
  K. Sakaguchi
- Organizer
  14th Akabori Conference
- Place of Presentation
  ニセコ町民センター（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Biomineralization and nanoparticle arrangement by Oligomeric Peptides2012
- Author(s)
  K. Sakaguchi
- Organizer
  Cambodian Malaysian Chemical Conference 2012
- Place of Presentation
  Angkor Century Resort and Spa(カンボジア)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Silver Nanocrystals Formed by Oligemeric Biomineralization Peptide via p53 Tetramerization Domain2012
- Author(s)
  T. Sakaguchi
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  かごしま県民交流センター(鹿児島県)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Silver Nanocrystals Formed by Oligemeric Biomineralization Peptide via p53 Tetramerization Domain2012
- Author(s)
  T. Sakaguchi
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  かごしま県民交流センター(鹿児島県)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Biomineralization and nanoparticle arrangement by Oligomeric Peptides2012
- Author(s)
  K. Sakaguchi
- Organizer
  Cambodian Malaysian Chemical Conference 2012
- Place of Presentation
  Angkor Century Resort and Spa (カンボジア)(招待講演)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Biomineralization and nanoparticle arrangement via paptide self-assembly2012
- Author(s)
  K. Sakaguchi
- Organizer
  Polish-Japanese Seminar
- Place of Presentation
  Akademia Gomiczo-Hutnicza University of Science Technology (ポーランド)(招待講演)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Ser/Thr specificity and metal prefeceince in human PPM1 family phosphatases2012
- Author(s)
  中馬吉郎・岩室良・白幡祐貴子・Jose Isagani B. Janairo・清田雄平・八木寛陽・坂口和靖
- Organizer
  第４９回ペプチド討論会
- Place of Presentation
  かごしま県民交流センター（鹿児島市）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Silver crystal formation by biomineralization peptide oligomerized through p53 tetramerization domain2012
- Author(s)
  T. Sakaguchi
- Organizer
  Polish-Japanese Seminar
- Place of Presentation
  Akademia Gomiczo-Hutnicza University of Science Technology (ポーランド)
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] p53四量体形成ドメインを用いたバイオミネラリゼーションペプチドによる銀粒子構造制御2012
- Author(s)
  T. Sakaguchi
- Organizer
  日本化学会北海道支部2012年夏季研究発表会
- Place of Presentation
  旭川工業高等専門学校 (北海道)
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Silver Nanocrystals Formed by Oligemeric Biomineralization Peptide via p53 Tetramerization Domain2012
- Author(s)
  T. Sakaguchi
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  かごしま県民交流センター（鹿児島県）
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Arrangement of Nanoparticle and Biomineralization through Peptide Self-assembly2011
- Author(s)
  K. Sakaguchi
- Organizer
  14th Asian Chemical Congress 2011(招待講演)
- Place of Presentation
  he Queen Sirikit National Convention Center （タイ）
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Abnormal nucleolar formation by overexpression of p53-inducible protein phosphatase PPM1D2011
- Author(s)
  K. Sakaguchi
- Organizer
  30th Annual Convention of Indian Association for Cancer Research
- Place of Presentation
  Indian Institute of Chemical Biology, CSIR, and Kolkata, India
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Arrangement of Nanoparticle and Biomineralization through Peptide Self-assembly2011
- Author(s)
  K.Sakaguchi
- Organizer
  14th Asian Chemical Congress 2011
- Place of Presentation
  The Queen Sirikit National Convention Center (タイ)(招待講演)
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Abnormal nucleolar formation by overexpression of p53-inducible protein phosphatase PPM1D.2011
- Author(s)
  K.Sakaguchi
- Organizer
  30th Annual Convention of Indian Association for Cancer Research
- Place of Presentation
  インド・コルカタ
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] Methylation of p53 Tetramerization Domain Arginine Residues Destabilizes the Tetrameric Structure2011
- Author(s)
  K. Sakaguchi
- Organizer
  22ndAmerican Peptide Symposium
- Place of Presentation
  Sheraton Hotel and Marina, San Diego, USA
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Methylation of p53Tetramerization Domain Arginine Residues Destabilizes the Tetrameric Structure2011
- Author(s)
  K. Sakaguchi
- Organizer
  22nd American Peptide Symposuim
- Place of Presentation
  Sheraton Hotel and Marina(アメリカ)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Abnormal nucleolar formation by overexpression of p53-inducible protein phosphatase PPM1D.2011
- Author(s)
  K.Sakaguchi
- Organizer
  30th Annual Convention of Indian Association for Cancer Research
- Place of Presentation
  インド・コルカタ招待講演
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Nanostructure formed by biomineralization peptide oligomerized via p53 tetramerization2011
- Author(s)
  T. Sakaguchi
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Methylation of p53 Tetramerization Domain Arginine Residues Destabilizes the Tetrameric Structure2011
- Author(s)
  K. Sakaguchi
- Organizer
  22nd American Peptide Symposuim
- Place of Presentation
  Sheraton Hotel and Marina（アメリカ）
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] Arrangement of Nanoparticle and Biomineralization through Peptide Self-assembly2011
- Author(s)
  K. Sakaguchi
- Organizer
  14th Asian Chemical Congress 2011
- Place of Presentation
  The Queen Sirikit National Convention Center, Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Methylation of p53 Tetramerization Domain Arginine Residues Destabilizes the Tetrameric Structure2011
- Author(s)
  K.Sakaguchi
- Organizer
  22nd American Peptide Symposuim
- Place of Presentation
  Sheraton Hotel and Marina (アメリカ)
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Arrangement of Nanoparticle and Biomineralization through Peptide Self-assembly2011
- Author(s)
  K. Sakaguchi
- Organizer
  14th Asian Chemical Congress 2011
- Place of Presentation
  The Queen Sirikit National Convention Center(タイ)
- Data Source
  KAKENHI-PROJECT-23651210
[Presentation] p53四量体形成ドメインとバイオミネラリゼーションペプチドの融合による銀粒子の構造制御2010
- Author(s)
  T.Sakaguchi
- Organizer
  日本化学会北海道支部2010年夏季研究発表会
- Place of Presentation
  函館工業高等専門学校
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Highly Effective Method for Functionalized Nanowire Formation by Mixing Multi Amyloid Peptides.2010
- Author(s)
  K.Sakaguchi
- Organizer
  13th Akabori Conference
- Place of Presentation
  ドイツ・ライプツイヒ
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] p53四量体形成ドメインとバイオミネラリゼーションペプチドの融合による銀粒子の構造制御2010
- Author(s)
  T.Sakaguchi
- Organizer
  日本化学会北海道支部2010年夏季研究発表会
- Place of Presentation
  函館工業高等専門学校
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] Highly Effective Method for Functionalized Nanowire Formation by Mixing Multi Amyloid Peptides.2010
- Author(s)
  K.Sakaguchi
- Organizer
  30th Annual Convention of Indian Association for Cancer Research
- Place of Presentation
  ドイツ・ライプツィヒ招待講演
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Highly Effective Method for Functionalized Nanowire Formation by Mixing Multi Amyloid Peptides2010
- Author(s)
  K. Sakaguchi
- Organizer
  13thAkabori Conference
- Place of Presentation
  Breitenfelder Hof, Leipzig, Germany
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53四量体形成ドメインを介した空間配向制御によるバイオミネラリゼーションの活性増強と構造制御2010
- Author(s)
  T.Sakaguchi
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学本部キャンパス
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Effect of Peptide Oligomerization Mediated by p53 Tetramerization Domain on Biomineralization Activity2010
- Author(s)
  T.Sakaguchi
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] Effect of Peptide Oligomerization Mediated by p53Tetramerization Domain on Biomineralization Activity2010
- Author(s)
  T. Sakaguchi, et al
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Effect of Peptide Oligomerization Mediated by p53 Tetramerization Domain on Biomineralization Activity2010
- Author(s)
  T.Sakaguchi
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53四量体形成ドメインを介した空間配向制御によるバイオミネラリゼーションの活性増強と構造制御2010
- Author(s)
  T.Sakaguchi
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学本部キャンパス
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] 分子情報生命科学:自己組織化を基盤とする機能性分子創成と界面構造2009
- Author(s)
  K.Sakaguchi
- Organizer
  分子情報生命科学シンポジウム
- Place of Presentation
  独立行政法人理化学研究所和光キャンパス(招待講演)
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] 分子情報生命科学:自己組織化を基盤とする機能性分子創成と界面構造2009
- Author(s)
  K.Sakaguchi
- Organizer
  分子情報生命科学シンポジウム
- Place of Presentation
  (独)理化学研究所和光キャンパス
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] p53四量体形成ドメインを介した多価minTBP-1のバイオメネラリゼーション活性2009
- Author(s)
  T.Sakaguchi
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21651088
[Presentation] p53四量体形成ドメインを介した多価minTBP-1のバイオメネラリゼーション活性2009
- Author(s)
  T.Sakaguchi
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] 分子情報生命科学:自己組織化を基盤とする機能性分子創成と界面構造2009
- Author(s)
  K. Sakaguchi
- Organizer
  分子情報生命科学シンポジウム
- Place of Presentation
  理化学研究所(和光市)
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Tetramerization Domain of Tumor Suppressor Protein p532008
- Author(s)
  K. Sakaguchi
- Organizer
  Taiwan-Japan International Symposium on Organic Chemistry and Molecular Science
- Place of Presentation
  台北・台湾
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Chemical and Structural Proteomics : The Solution to Biological Problems2008
- Author(s)
  K. Sakaguchi
- Organizer
  MPSA2008
- Place of Presentation
  Sapporo
- Year and Date
  2008-08-26
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Tetramerization of Tumor Suppressor Protein p532008
- Author(s)
  K. Sakaguchi
- Organizer
  12th Akabori Conference German - Japanese Symposium on Peptide Science
- Place of Presentation
  京都プラザホテル・京都
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Tetramerization Domain of Tumor Suppressor Protein p532008
- Author(s)
  K. Sakaguchi
- Organizer
  Taiwan-Japan International Symposium on Organic Chemistry and Molecular Science
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Structure Control of Amyloid Peptide Nanofibrils2008
- Author(s)
  K. Sakaguchi
- Organizer
  The 10th RIES-Hokudai International Symposium
- Place of Presentation
  北海道大学学術交流会館・札幌
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Tetramerization of tumor suppressor protein p532008
- Author(s)
  K. Sakaguchi
- Organizer
  12th Akabori Conference : German-Japanese Symposium on Peptide Science
- Place of Presentation
  Kyoto
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Functional Bionanomaterial Based on Peptide Self-assembly2008
- Author(s)
  K. Sakaguchi
- Organizer
  International Symposium on Molecular and System Life Sciences
- Place of Presentation
  理研・神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Correlation of Oligomeric Structure and Transcriptional Activity of p53 Mutants2007
- Author(s)
  坂口和靖
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山国際会議場(富山)
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] 癌抑制タンパク質p53四量体形成ドメイン2007
- Author(s)
  坂口和靖
- Organizer
  日本バイオインフォマティクス学会北海道地域部会
- Place of Presentation
  札幌
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Correlation of oligomeric Structure and Transcritional Activity of p53 Mutants2007
- Author(s)
  坂口和靖, 他
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] Control of Biomineralization and Nanoparticle Arrangement via Peptide Self-assembly by 3D Structure Element
- Author(s)
  K. Sakaguchi
- Organizer
  2013 SNU-HU Chemistry Symposium
- Place of Presentation
  ソウル大（韓国）
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Destabilization of p53 Tetramer Formation by Arginine Methylation
- Author(s)
  J. Wada, R. Kamada, T. Imagawa, and K. Sakaguchi
- Organizer
  the 10th Nanjing-Hokkaido-NIMS/MANA Joint Symposium
- Place of Presentation
  ルスツリゾート（北海道）
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Silver Nanoparticles formed by Oligomeric Biomineralization Peptide Conjugated with DNA
- Author(s)
  T. Sakaguchi, S. Sasaki, K. Mine, and K. Sakaguchi
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学（徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Induction of genome instability by overexpression of PPM1D phosphatase in cancer cells
- Author(s)
  Yoshiro Chuman, Sari Ogasawara, Akihiro Fujita, Yuuki Kozakai, and Kazuyasu Sakaguchi
- Organizer
  第11回プロテインホスファターゼ国際学会
- Place of Presentation
  東北大学(仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] DNA高次構造体を介した多量体化バイオミネラリゼーションペプチドによる銀ナノ構造体形成
- Author(s)
  峯健太、坂口達也、佐々木慎一郎、中馬吉郎、鎌田瑠泉、坂口和靖
- Organizer
  化学系学協会北海道支部2015年冬季研究発表会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2015-01-27 – 2015-01-28
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Effects of Oligomerization and Orientation of Biomineralization Peptides on Formation and Structure of Silver Nanoparticles
- Author(s)
  T. Sakaguchi, J. I. B. Janairo, Y. Chuman, and K. Sakaguchi
- Organizer
  Frontier Chemistry Center the 3rd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Changes in Tetramerization Domain of Tumor Suppressor Protein p53 in Tumorigenesis and Evolution
- Author(s)
  K. Sakaguchi
- Organizer
  15th Akabori Conference Japanese-German Symposium on Peptide Science
- Place of Presentation
  Best Western Premier Bellevue Rheinhotel (Germany)
- Year and Date
  2014-09-07 – 2014-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Development of small molecule PPM1D phosphatase inhibitors
- Author(s)
  Sari Ogasawara, Yuhei Kiyota, Yoshiro Chuman, Fumihiko Yoshimura, Keiji Tanino, Kazuyasu Sakaguchi
- Organizer
  第11回プロテインホスファターゼ国際学会
- Place of Presentation
  東北大学(仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Control of Biomineralization and Nanoparticle Arrangement via Peptide Self-assembly and Oligomerization
- Author(s)
  K. Sakaguchi
- Organizer
  NIMS/MANA Seminar
- Place of Presentation
  NIMS（つくば市）
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Analysis of p53 Mutation for Dominant Negative Effect in Transcriptional Activity
- Author(s)
  Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
- Organizer
  Frontier Chemistry Center the 3rd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] DNA高次構造体を介した多量体化バイオミネラリゼーションペプチドによる銀ナノ構造体形成
- Author(s)
  峯健太、坂口達也、佐々木慎一郎、中馬吉郎、鎌田瑠依、坂口和靖
- Organizer
  日本化学会北海道支部2015年冬季研究発表会
- Place of Presentation
  北海道大学(札幌市）
- Year and Date
  2015-01-27 – 2015-01-28
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Enhancing Pd Biomineralization through Manipulation of Peptide Spatial Orientation and Buffer Selection
- Author(s)
  J. I. B. Janairo, T. Sakaguchi, and K. Sakaguchi
- Organizer
  Frontier Chemistry Center the 3rd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Effects of p53 Tetramerization Domain Mutants found in Li-Fraumeni Syndrome on Hetero-oligomerization and Transcriptional Activity
- Author(s)
  M. Kanno, T. Imagawa, Y. Toguchi, R. Kamada, and K. Sakaguchi
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Analysis of Stability of Tetrameric Structure and Transcriptional Activity in Evolution of Tumor Suppressor Protein p53
- Author(s)
  J. Wada, T. Nomura, R. Kamada, T. Imagawa, and K. Sakaguchi
- Organizer
  Methods in Protein Structure Analysis 2014
- Place of Presentation
  Base Village Conference Center (U.S.A)
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Changes of Structural Stability of p53 Tetramerization Domain by Arginine Methylation
- Author(s)
  J. Wada, R. Kamada, T. Imagawa, and K. Sakaguchi
- Organizer
  Frontier Chemistry Center the 3rd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] PPM1Dホスファターゼ過剰発現による染色体不安定化機構
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、水上洋平、今川敏明、坂口和靖
- Organizer
  第４９回ペプチド討論会
- Place of Presentation
  徳島大学大塚講堂(徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Methylation of the Tetramerization Domain in Tumor Suppressor Protein p53 by PRMT
- Author(s)
  N. Nakagawa, J. Wada, R. Kamada, and K. Sakaguchi
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学（徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] 生細胞蛍光イメージングのための新規細胞質特異的プローブ
- Author(s)
  鎌田瑠泉、田野史、大澤歩、工藤風樹、中馬吉郎、難波康祐、谷野圭持、坂口和靖
- Organizer
  日本化学会第95春季年会（2015）
- Place of Presentation
  日本大学（船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] 蛍光レポーターアッセイを用いた定量的解析によるヘテロ四量体p53の転写活性化能
- Author(s)
  戸口侑、菅野まどか、今川敏明、坂口和靖
- Organizer
  第79回日本インターフェロンサイトカイン学会学術集会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Quantitative Analysis of p53 Hetero-tetramers for Dominant Negative Effect in Transcriptional Activity
- Author(s)
  Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学(徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Analysis of Active Sites in Human PPM1 Phosphatase Family
- Author(s)
  Yuhei Kiyota, Sari Ogasawara, Yukiko Shirahata, Yutaka Matsuyama, Yuichi Nishimura, Yoshiro Chuman Yasuyuki Shimohigashi and Kazuyasu Sakaguchi
- Organizer
  第11回プロテインホスファターゼ国際学会
- Place of Presentation
  東北大学(仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Amino Acid Substitution in Tetramerization Domain of Tumor Suppressor Protein p53 in Tumorigenesis and Evolution
- Author(s)
  K. Sakaguchi
- Organizer
  the 10th Nanjing-Hokkaido-NIMS/MANA Joint Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-08-22 – 2014-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] 多量体型scaffoldに融合したバイオミネラリゼーションペプチドの銀粒子形成
- Author(s)
  坂口達也
- Organizer
  日本化学会北海道支部　２０１３年　夏季研究発表会
- Place of Presentation
  北見工業大学（北見市）
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Tetramer Formation of Tummor Suppressor Protein p53: Mutation, Evolution and Application
- Author(s)
  K. Sakaguchi
- Organizer
  Frontier Chemistry Center the 3rd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-13 – 2014-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Hetero-oligomerization of the WildI-type and Mutant Tumor Suppessor Protein p53
- Author(s)
  Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
- Organizer
  5th Symposium on Academic Exchange and Collaborative Research (AECoR-5)
- Place of Presentation
  ETH Zurich（Switzerland）
- Year and Date
  2014-11-27 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Mutation and Evolution of Tetramerization Domain in Tumor Suppressor Protein p53
- Author(s)
  K. Sakaguchi
- Organizer
  18th Korean Peptide Protein Society Symposium
- Place of Presentation
  Hanwha Resort Haeundae (Korea)
- Year and Date
  2014-06-07 – 2014-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-24310152

1. CHUMAN Yoshiro (40372263)

# of Collaborated Projects: 6 results

# of Collaborated Products: 42 results
2. SHIMOHIGASHI Yasuyuki (00211293)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. TOSHIAKI Imagawa (20142177)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
4. 鎌田瑠泉 (40750881)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 嘉屋俊二 (90186023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKUDA Eri

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. NAMBA Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. NAKAYAMA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 八木寛陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 吉村文彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 谷野圭持

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 原賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 下東美樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakaguchi Kazuyasu 坂口 和靖

坂口 和靖 サカグチ カズヤス

SAKAGUCHI Kazuyasu 坂口 和靖

Research Projects

Research Products

Co-Researchers

Development of a novel genome editing method through transient arrest control of the tumor suppressor protein p53Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細菌リボソームRNAにコードされ生存危機ストレスにより翻訳される防御ポリペプチドPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new method for identifying substrates of PPM1 phosphatase familyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Control of Bioreaction via Oligomerization and Orientation of Tumor Suppressor Protein p53 TetramerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the molecular mechanism of genome instability in the cells with overexpression of PPM1D

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stability Change of Tetrameric Structure of Tumor Suppressor Protein p53 in Mutation and Evolution, and Threshold for Loss of Tumor Suppressor Activity in Terms of Disruption of the Tetrameric Structure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

E‐Life構築を目指したD型タンパク質翻訳系の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inactivation of Tumor Suppressor Protein p53 by Mutations in the Tetramerization Domain and Stabilizing Methods for the Tetrameric StructurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん抑制タンパク質p53の四量体形成ドメインのフォールディングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

酸化ストレス解析のための特異的モノクローナル抗体作製法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design and development of tumor suppressor protein p53 variant that cannot form heterooligomers with the wild-type proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

p53誘導性ホスファターゼWip1の局在化とSH3蛋白質を介した細胞周期の制御Principal Investigator

Principal Investigator

Sakaguchi Kazuyasu 坂口和靖

坂口和靖サカグチカズヤス

SAKAGUCHI Kazuyasu 坂口和靖