Hashimoto Yuichi 橋本祐一

… Alternative Names

HASHIMOTO Yuuichi 橋本祐一

HASHIMOTO Yuichi 橋本祐一

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Researcher Number	00317330
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 東京医科大学, 医学部, 講師 2010 – 2015: 東京医科大学, 医学部, 講師 2007: Keio University, School of Medicine, Instructor 2000 – 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Drug development chemistry / General pharmacology / Basic Section 59040:Nutrition science and health science-related / Neurology Except Principal Investigator Neurology / Experimental pathology
Keywords	Principal Investigator ヒューマニン / 神経細胞死 / アルツハイマー病 / STAT3 / アミロイド前駆体タンパク質 / プレセニリン / Humanin / Alzheimer's disease / 受容体 / 細胞内シグナル伝達 … More / サイトカイン / 神経変性疾患 / アミロイドβペプチド / アミロイド前駆体蛋白質 / 細胞老化 / small comoound / receptor / cytokine / neurocnal cell death / Transforming Growth Factor β / 小分子化合物 / transforming growth factor β2 / amyloid precursor protein / neuronal cell death / PLAIDD / p75ニューロトロフィン受容体 / APP / シグナル伝達 / TGFβ2 / 神経科学 / Apollon / UNC5C / CLSP / 創薬化学 / 細胞内シグナル伝 / 治療薬 / スクリーニング / プレセリン … More Except Principal Investigator アルツハイマー病 / receptor / serine isomerase / dimerization / neurodegenerative disease / Alzheimer's disease / Humanin / βFGF / IGF-I / 生体内発現 / ADNF / bFGF / IGF-1 / 分泌機構 / 構造機能相関 / HN / 癌治療 / 細胞死 / 細胞癌化 / ヒューマニン / 神経細胞 / 疾患モデル / 分化誘導 / ノックイン / ES細胞 Less

ミトコンドリア由来ペプチドによる老化制御機構の解明Principal Investigator
- Principal Investigator
  
  橋本祐一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Medical University
Identification of Alzheimer's disease-relevant neuronal death inhibiting molecular basis and its application for drug developmentPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO YUICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo Medical University
Search for neuronal cell death-inhibiting drugs for Alzheimer's disease-relevant signal transductionPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Yuuichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo Medical University
Estblishment of curative therapy for Alzheimer's disease with Humanin peptidesPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Yuichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Keio University
アルツハイマー病抑制因子ヒユーマニンの発癌作用の検討
- Principal Investigator
  
  MATSUOKA Masaaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
Establishment of curative therapy for Alzheimer's disease with Humanin peptidesPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Yuichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  KEIO University
アミロイド前駆体蛋白の変異導入ES細胞を用いたアルツハイマー病神経細胞の確立
- Principal Investigator
  
  阿部陽一郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Keio University
Detailed characterization of Humanin, a newly identified anti-Alzheimer's disease peptide and potential starting point for development of the first curative therapy for Alzheimer's disease
- Principal Investigator
  
  NISHIMOTO Ikuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  KEIO UNIVERSITY
アルツハイマー病原因遺伝子による神経細胞死に対する拮抗遺伝子と分子装置の解明Principal Investigator
- Principal Investigator
  
  橋本祐一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Keio University

All 2016 2015 2014 2013 2012 2011 2010 2007 2006 2005 2004 2001

All Journal Article Presentation

[Journal Article] Apollon/Bruce is upregulated by Humanin.2014
- Author(s)
  4.Hashimoto, Y., Takeshita, Y., Naito, M., Uchino, H. and Matsuoka, M
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 397 Issue: 1-2 Pages: 147-55
- DOI
  10.1007/s11010-014-2182-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460084, KAKENHI-PROJECT-25460343
[Journal Article] A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity2014
- Author(s)
  Hashimoto Y, Matsuoka M
- Journal Title
  
  J Neurochem
  
  Volume: not decided Issue: 2 Pages: 291-300
- DOI
  10.1111/jnc.12717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-25460343
[Journal Article] SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide Humanin by inhibiting c-Jun NH2-teminal kinase2013
- Author(s)
  Takeshita Y, Hashimoto Y, Nawa M, Uchino H, Matsuoka M
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 34 Pages: 24691-24704
- DOI
  10.1074/jbc.m113.469692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-24790264, KAKENHI-PROJECT-25460343
[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.2013
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M.
- Journal Title
  
  NeuroReport
  
  Volume: 25 Issue: 9 Pages: 751-735
- DOI
  10.1097/wnr.0b013e328362d9fe
- NAID
  120005407941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460343
[Journal Article] Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptor2013
- Author(s)
  Hashimoto Y, Nawa M, Kurita M, Tokizawa M,Iwamatsu A, Matsuoka M
- Journal Title
  
  Cell Death Dis
  
  Volume: 4 Issue: 3 Pages: 555-555
- DOI
  10.1038/cddis.2013.80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247, KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23659784, KAKENHI-PROJECT-24790264, KAKENHI-PROJECT-25460343
[Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer 's disease-related mutants of amyloid beta precursor protein and presenilin2012
- Author(s)
  Tachi N, Hashimoto Y, Matsuoka M
- Journal Title
  
  Biochem. J
  
  Volume: 442 Issue: 2 Pages: 413-422
- DOI
  10.1042/bj20100993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] Caricasole AVSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin2011
- Author(s)
  Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M
- Journal Title
  
  FASEB J.
  
  Volume: 25 Issue: 6 Pages: 1983-2000
- DOI
  10.1096/fj.10-163535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin2011
- Author(s)
  Rossini, L, Hashimoto, Y., et al
- Journal Title
  
  FASEB Journal
  
  Volume: 25(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] TAG-1 in an inhibitor of TGFβ2-induced neuronal cell death via amyloid β precursor protein2010
- Author(s)
  Tachi, N., Hashimoto, Y., et al
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 394 Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] Humanin and the receptors for Humanin2010
- Author(s)
  Matsuoka, M., Hashimoto, Y.
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 41 Pages: 22-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] Transforming growth factor β2 autocrinally mediates neurona cell death induced by amyloid-β.2006
- Author(s)
  Yuichi Hashimoto
- Journal Title
  
  Journal of Neuroscience Research 83
  
  Pages: 1039-1047
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Transforming growth factor β2 autocrinally mediates neuronal cell death induced by amyloid-β.2006
- Author(s)
  Hashimoto Y. et al.
- Journal Title
  
  J.Neurosci.Res. (in press)
- Data Source
  KAKENHI-PROJECT-17659117
[Journal Article] Transforming growth factor β2 autocrinally mediates neuronal cell death induced by amyloid-β.2006
- Author(s)
  Hashimoto Y, Nawa M, Chiba T, Suzuki H, Aiso S, Nishimoto I, Matsuoka M
- Journal Title
  
  Journal of Neuroscience Research 83
  
  Pages: 1039-1047
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-b.2006
- Author(s)
  Yuichi Hashimoto. et al.
- Journal Title
  
  Journal of Neuroscience Research 83・6
  
  Pages: 1039-1047
- Data Source
  KAKENHI-PROJECT-18590106
[Journal Article] Transforming growth factor β2 autocrinally mediates neuronal cell death induced by amyloid-β.2006
- Author(s)
  Yuichi Hashimoto(橋本祐一)
- Journal Title
  
  Journal of Neuroscience Research (印刷中)
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta2006
- Author(s)
  Hashimoto Y. et al.
- Journal Title
  
  Journal of Neuroscience Research 83・6
  
  Pages: 1039-1047
- Data Source
  KAKENHI-PROJECT-17659117
[Journal Article] Transforming growth factor β2 is a neuronal cell death-inducing ligand for amyloid-β precursor protein.2005
- Author(s)
  Yuichi Hashimoto(橋本祐一)
- Journal Title
  
  Molecular and Cellular Biology 25
  
  Pages: 9304-9317
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection.2005
- Author(s)
  Hashimoto Y. et al.
- Journal Title
  
  Life Sci. 77
  
  Pages: 3092-3104
- Data Source
  KAKENHI-PROJECT-17659117
[Journal Article] Transforming growth factor beta 2 is a neuronal death-inducing ligand for amyloid-beta precursor protein.2005
- Author(s)
  Hashimoto Y. et al.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 9304-9317
- Data Source
  KAKENHI-PROJECT-17659117
[Journal Article] Involvement of tyrosine kinases and STAT3 in Humanin-mediate neuroprotection2005
- Author(s)
  Yuichi Hashimoto
- Journal Title
  
  Life Sciences 77
  
  Pages: 3092-3104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Transforming growth factor β2 is a neuronal cell death- inducing ligand for amyloid-β precursor protein.2005
- Author(s)
  Yuichi Hashimoto
- Journal Title
  
  Molecular and Cellular Biology 25
  
  Pages: 9304-9317
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection2005
- Author(s)
  Yuichi Hashimoto(橋本祐一)
- Journal Title
  
  Life Sciences 77
  
  Pages: 3092-3104
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Transforming growth factor β2 is a neuronal cell death-inducing ligand for amyloid-β precursor protein.2005
- Author(s)
  Hashimoto Y, Chiba T, Yamada M, Nawa M, Kita Y, Kanekura K, Suzuki H, Terashita K, Aiso S, Nishimoto I, Matsuoka M
- Journal Title
  
  Molecular and Cellular Biology 25
  
  Pages: 9304-9317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection2005
- Author(s)
  Hashimoto Y, Suzuki H, Aiso S, Niikura T, Nishimoto I, Matsuoka M
- Journal Title
  
  Life Sciences 77
  
  Pages: 3092-3104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Molecular characterization of neuronal cell death by Alzheimer's amyloid-β peptides via p75NTR/PLAIDD2004
- Author(s)
  Hashimoto Y, Kaneko Y, Tsukamoto E, Frankowski H, Kouyama K, Kita Y, Niikura T, Aiso S, Bredesen DE, Matsuoka M, Nishimoto I
- Journal Title
  
  Journal of Neurochemistry 90
  
  Pages: 549-558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Humanin antagonists : mutants that interfere with dimerization inhibit neuroprotection by Humanin.2004
- Author(s)
  Yuichi Hashimoto
- Journal Title
  
  European Journal of Neuroscience 19
  
  Pages: 2356-2364
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Molecular characterization of neuronal cell death by Alzheimer's a myloid-β peptides via p75NTR/PLADD2004
- Author(s)
  Hashimoto Y.
- Journal Title
  
  Journal of Neurochemistry 90
  
  Pages: 549-558
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Cytotoxic mechanisms by M239V presenilin 2, a little analyzed Alzheimer's disease-causative mutant.2004
- Author(s)
  Abe Y, Hashimoto Y.
- Journal Title
  
  Journal of Neuroscience Research 77
  
  Pages: 583-595
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Molecular characterization of neuronal cell death by Alzheimer's amyloid-β peptides via p75NTR/PLAIDD2004
- Author(s)
  Yuichi Hashimoto
- Journal Title
  
  Journal of Neurochemistry 90
  
  Pages: 549-558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Humanin antagonists : mutants that interfere with dimerization inhibit neuroprotection by Humanin.2004
- Author(s)
  Hashimoto Y.
- Journal Title
  
  European Journal of Neuroscience 19
  
  Pages: 2356-2364
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] Humanin antagonists : mutants that interfere with dimerization inhibit neuroprotection by Humanin.2004
- Author(s)
  Hashimoto Y, Terashita K, Niikura T, Yamagishi Y, Ishizaka M, Kanekura K, Chiba T, Yamada M, Kita Y, Matsuoka M, Aiso S, Nishimoto I
- Journal Title
  
  European Journal of Neuroscience 19
  
  Pages: 2356-2364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590088
[Journal Article] A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ.2001
- Author(s)
  Hashimoto Y., et al.
- Journal Title
  
  Proceedings of National Academy of the United States of America 98(22)
  
  Pages: 6336-6341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13307022
[Journal Article] Detailed characterization of neuroprotection by a rescue factor Humanin against various Alzheimer's disease-relevant insults.2001
- Author(s)
  Hashimoto Y., et al.
- Journal Title
  
  The Journal of Neuroscience 21(23)
  
  Pages: 9235-9245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13307022
[Journal Article] A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ.2001
- Author(s)
  Hashimoto Y, et al.
- Journal Title
  
  Proceedings of National Academy of Sciences, USA 98
  
  Pages: 6336-6341
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13307022
[Journal Article] Detailed characterization of neuroprotection by a rescue factor Humanin against various Alzheimer's disease-relevant insults.2001
- Author(s)
  Hashimoto Y, et al.
- Journal Title
  
  The Journal of Neuroscience 21
  
  Pages: 9235-9245
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13307022
[Presentation] An Alzheimer's disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade.2016
- Author(s)
  橋本祐一　外山由夏　松岡正明
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜　会議センター
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] An Alzheimer's disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2015
- Author(s)
  Yuchi Hashimoto Masaaki Matsuoka
- Organizer
  Society for Neuroscience 2015, SfN's 45th Annual Meeting
- Place of Presentation
  米国　シカゴ市
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] An anti-Alzheimer’s disease mutation makes amyloid precursor protein unable to mediate transforming growth factor β2-induced neurotoxicity2014
- Author(s)
  Hashimoto Y, Matsuoka M.
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] Apollon/Bruce is upregulated by Humanin2014
- Author(s)
  橋本祐一　竹下裕二　内藤幹彦　内野博之　松岡正明
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  東北大学
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] SH3-binding protein 5 mediates the neuroprotective effect of Humanin by inhibiting c-Jun NH2-terminal kinase2013
- Author(s)
  Hashimoto Y, Takeshita Y, Nawa M, Uchino H, Matsuoka M.
- Organizer
  Society for Neuroscience 43rd annual meeting 2013
- Place of Presentation
  アメリカ合衆国カリフォルニア州サンディエゴ市
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer's disease-relevant toxicity2013
- Author(s)
  竹下裕二、橋本祐一、内野博之、松岡正明
- Organizer
  日本薬理学会第86回大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Involvement of MOCA in neuronal cell death triggered by familial Alzheimer's disease-linked mutants of APP and presenilins2011
- Author(s)
  Hashimoto, Y., et al.
- Organizer
  第84回日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2011-03-16
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Involvement of MOCA in Alzheimer's disease-relevant neuronal cell death via APP and presenilins2011
- Author(s)
  Yuichi Hashimoto
- Organizer
  Society for Neuroscience 2011 Annual Meeting
- Place of Presentation
  米国ワシントンD.C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Involvement of MOCA in Alzheimer ' s disease-relevant neuronal cell death via APP and presenilins2011
- Author(s)
  Hashimoto Y, Tachi N, Matsuoka M
- Organizer
  Society for Neuroscience 2011 Annual Meeting
- Place of Presentation
  ワシントン D.C
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Involvement of MOCA in neuronal cell death triggered by familial Alzheimer's disease-linked mutants of APP and presenilins.2011
- Author(s)
  橋本祐一、太知信之、名和幹朗、松岡正明
- Organizer
  日本薬理学会第84回大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-16
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Humanin inhibits neuronal death via a CNTF receptor a/WSX-1/gp 130 complex2007
- Author(s)
  Yuichi, Hashimoto, Megumi, Kurita, Ikuo, Nishimoto, Sadakazu, Aiso, Masaaki, Matsuoka
- Organizer
  Society for Neuroscience 2007 Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590106
[Presentation] Humanin inhibits neuronal death via a CNTF receptor α/WSX-1/gp130 complex2007
- Author(s)
  Yuichi Hashimoto
- Organizer
  Society for Neuroscience 2007 Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590106

1. MATSUOKA Masaaki (70222297)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. NIIKURA Takako (10301491)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NISHIMOTO Ikuo (80180652)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 阿部陽一郎 (10317331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 安川孝史 (60291936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 田島裕久 (50306833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 内藤幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Yuichi 橋本 祐一

HASHIMOTO Yuuichi 橋本 祐一

HASHIMOTO Yuichi 橋本 祐一

Research Projects

Research Products

Co-Researchers

ミトコンドリア由来ペプチドによる老化制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Alzheimer's disease-relevant neuronal death inhibiting molecular basis and its application for drug developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for neuronal cell death-inhibiting drugs for Alzheimer's disease-relevant signal transductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Estblishment of curative therapy for Alzheimer's disease with Humanin peptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルツハイマー病抑制因子ヒユーマニンの発癌作用の検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of curative therapy for Alzheimer's disease with Humanin peptidesPrincipal Investigator

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アミロイド前駆体蛋白の変異導入ES細胞を用いたアルツハイマー病神経細胞の確立

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Detailed characterization of Humanin, a newly identified anti-Alzheimer's disease peptide and potential starting point for development of the first curative therapy for Alzheimer's disease

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アルツハイマー病原因遺伝子による神経細胞死に対する拮抗遺伝子と分子装置の解明Principal Investigator

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[Journal Article] Apollon/Bruce is upregulated by Humanin.2014

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[Journal Article] A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity2014

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[Journal Article] SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide Humanin by inhibiting c-Jun NH2-teminal kinase2013

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[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.2013

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Hashimoto Yuichi 橋本祐一

HASHIMOTO Yuuichi 橋本祐一

HASHIMOTO Yuichi 橋本祐一