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KOYANAGI Masamichi  小柳 雅孔

ORCIDConnect your ORCID iD *help
… Alternative Names

小柳 雅孔  コヤナギ マサミチ

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Researcher Number 00325474
Affiliation (based on the past Project Information) *help 2011 – 2017: 九州大学, 大学病院, 助教
2014: 九州大学病院別府病院, 内科, 助教
2013: 九州大学病院, 別府病院, 助教
2001 – 2002: 九州大学, 生体防御医学研究所, 助手
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine
Except Principal Investigator
General internal medicine(including psychosomatic medicine) / Circulatory organs internal medicine / Circulatory organs internal medicine / General internal medicine (including Psychosomatic medicine)
Keywords
Principal Investigator
循環器内科学 / 国際情報交換(ドイツ) / Wntシグナル / エピジェネティック / 再生医療 / エピジェネテックス / 心血管リモデリング / アンジオテンシン変換酵素 / 動脈硬化 / 一酸化窒素 / MCP-1 / 単球・マクロファージ … More
Except Principal Investigator
… More MMP / PPAR-r / サイトカイン / テロメア / 老化 / DNA / 温熱 / 生物学的老化 / NFκ-B / Cytokines / Brain Natriuretic Peptide / Cardiac Remodeling / TIMP / TNF-alpha / 心筋細胞 / 低酸素 / マトリックスメタロプロテアーゼ / NFk-b / BNP / 心筋リモデリング / 近赤外線レーザー / 心臓局所温熱 / トランスジェニックマウス / ナノテクノロジー / 循環器 / 温熱療法 / 心不全 / 金ナノロッド / 血管内皮細胞 / 白血球 / 環状DNA Less
  • Research Projects

    (6 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (10 People)
  •  The development of aging parameters by serum telomere DNA analysis

    • Principal Investigator
      Maeda Toyoki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Kyushu University
  •  Targeted heart hyperthermia for heart failure using gold nano-rod

    • Principal Investigator
      HIGUCHI Yoshihiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  The evaluation of genomic aging by quantifying telomeric circular DNA in peripheral leukocytes of patients with chronic disease.

    • Principal Investigator
      MAEDA Toyoki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kyushu University
  •  Epigenetic control of cardiac gene expressions by non-canonical WntsPrincipal Investigator

    • Principal Investigator
      KOYANAGI Masamichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Matrix Degradative Enzyme Activities on Cardiac Remodeling in Heart Failure

    • Principal Investigator
      MAKINO Naoki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  動脈硬化の分子療法(抗ケモカイン療法)の開発Principal Investigator

    • Principal Investigator
      小柳 雅孔
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University

All 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

  • [Book] Title; Circulating progenitor cells a part of"HEART REGENERATION Stem Cells and Beyond"2012

    • Author(s)
      Masamichi Koyanagi and Stefanie Dimmeler
    • Publisher
      Pub.
    • Data Source
      KAKENHI-PROJECT-23591083
  • [Journal Article] FoxO1 signaling plays a pivotal role in the cardiac telomere biology responses to calorie restriction.2016

    • Author(s)
      Makino N, Oyama J, Maeda T, Koyanagi M, Higuchi Y, Shimokawa I, Mori N, Furuyama T.
    • Journal Title

      Mol Cell Biochem.

      Volume: 412 Issue: 1-2 Pages: 119-130

    • DOI

      10.1007/s11010-015-2615-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08142, KAKENHI-PROJECT-15H04682, KAKENHI-PROJECT-15K08919, KAKENHI-PROJECT-15K14352
  • [Journal Article] Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts.2015

    • Author(s)
      Makino N, Oyama J, Maeda T, Koyanagi M, Higuchi Y, Tsuchida K.
    • Journal Title

      Mol Cell Biochem

      Volume: 403 Issue: 1-2 Pages: 1-11

    • DOI

      10.1007/s11010-015-2327-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08919
  • [Journal Article] X-irradiation alters the telomerase activity and the telomere length distribution of cultured human vascular endothelial cells2014

    • Author(s)
      Toyoki Maeda, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino
    • Journal Title

      Appl Cell Biol

      Volume: 3

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] X-irradiation alters the telomerase activity and the telomere length distribution of cultured human vascular endothelial cells.2014

    • Author(s)
      Toyoki Maeda1, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino.
    • Journal Title

      Appl Cell Biol

      Volume: 3 Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Vascular endothelial cell surviving through under prolonged elevated temperature shows persistent or transient up-regulation of telomerase and stress-associated proteins.2014

    • Author(s)
      Toyoki Maeda1, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino.
    • Journal Title

      Appl Cell Biol

      Volume: 3 Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Vascular endothelial cell surviving through under prolonged elevated temperature shows persistent or transient up-regulation of telomerase and stress-associated proteins2014

    • Author(s)
      Toyoki Maeda, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino
    • Journal Title

      Appl Cell Biol

      Volume: 2

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Alterations in the telomere length distribution and the subtelomeric methylation status in human vascular endothelial cells under elevated temperature in culture condition2013

    • Author(s)
      Maeda T, G. Jing-Zhi, Koyanagi M Makino N
    • Journal Title

      Aging Clin Exp Res

      Volume: 25 Pages: 231-238

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Alterations in the telomere length distribution and the subtelomeric methylation status in human vascular endothelial cells under elevated temperature in culture condition.2013

    • Author(s)
      Maeda T, Guan JZ, Koyanagi M, Makino N.
    • Journal Title

      Aging Clin Exp Res.

      Volume: 25 Issue: 3 Pages: 231-238

    • DOI

      10.1007/s40520-013-0045-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590885, KAKENHI-PROJECT-23591083
  • [Journal Article] Telomerase activity and telomere length distribution in vascular endothelial cell in a short-term culture under the presence of hydrogen peroxide2013

    • Author(s)
      Maeda T, Jing-Zhi Guan, Koyanagi M, Makino N
    • Journal Title

      Geriatrics and Gerontology International

      Volume: 13 Pages: 774-782

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Telomerase activity and telomere length distribution in vascular endothelial cells in a short-term culture under the presence of hydrogen peroxide.2013

    • Author(s)
      Maeda T, Guan JZ, Koyanagi M, Makino N.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: 13 Issue: 3 Pages: 774-782

    • DOI

      10.1111/j.1447-0594.2012.00936.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Acute myocardial infarction activates progenitor cells and increases Wnt signaling in the bone marrow2012

    • Author(s)
      Assmus B, Iwasaki M, Schächinger V, Roexe T, Koyanagi M, Iekushi K, Xu Q, Tonn T, Seifried E, Liebner S, Kranert WT, Gruenwald F, Dimmeler S, Zeiher AM
    • Journal Title

      Eur Heart J

      Volume: 33(15) Issue: 15 Pages: 1911-9

    • DOI

      10.1093/eurheartj/ehr388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591083
  • [Journal Article] The gender-related alterations in the telomere length and subtelomeric methylation status in patients with Parkinson's disease2012

    • Author(s)
      Maeda T, Jing-Zhi Guan, Koyanagi M, Makino N
    • Journal Title

      Ageing Res

      Volume: 4 Pages: 61-66

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Aging-associated alteration of telomere length and subtelomeric status in female patients with Parkinson's disease.2012

    • Author(s)
      Maeda T, Guan JZ, Koyanagi M, Higuchi Y, Makino N.
    • Journal Title

      Journal of Neurogenetics

      Volume: 26 Issue: 2 Pages: 245-251

    • DOI

      10.3109/01677063.2011.651665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590885, KAKENHI-PROJECT-23591083
  • [Journal Article] Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-alpha overexpression2012

    • Author(s)
      Higuchi Y, Kubota T, Koyanagi M, Maeda T, Feldman AM, Makino N.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 302(11) Issue: 11 Pages: H2352-H2362

    • DOI

      10.1152/ajpheart.01026.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591083, KAKENHI-PROJECT-24591098
  • [Journal Article] Aging-associated alteration of telomere length and subtelomeric status in female patients with Parkinson's disease2012

    • Author(s)
      Toyoki Maeda, Jing Zhi Guan, Masamichi Koyanagi, Yoshihiro Higuchi, Naoki Makino
    • Journal Title

      Neurogenetics

      Volume: 26 Pages: 245-251

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Upregulation of Anticoagulant Proteins, Protein S and Tissue Factor Pathway Inhibitor, in the Mouse Myocardium with Cardio-Specific TNF- x03B1; Overexpression2012

    • Author(s)
      Yosihiro Higuchi, Masamichi Koyanagi, Toru Kubota, Toyoki Maeda, Arthur Feldman, Naoki Makino
    • Journal Title

      Am J Physiol-Heart Circ Physiol

      Volume: 302

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] Hepatocyte Growth Factor Induces a Proangiogenic Phenotype and Mobilizes Endothelial Progenitor Cells by Activating Nox22011

    • Author(s)
      Schroder, K; Schutz, S; Schloffel, I; Batz, S; Takac, I; Weissmann, N; Michaelis, UR; Koyanagi, M; Brandes,RP
    • Journal Title

      ANTIOXIDANTS & REDOX SIGNALING

      Volume: 15巻4号 Issue: 4 Pages: 915-923

    • DOI

      10.1089/ars.2010.3533

    • Data Source
      KAKENHI-PROJECT-23591083
  • [Journal Article] Epigenetic Regulation of Endothelial Lineage Committed Genes in Pro-Angiogenic Hematopoietic and Endothelial Progenitor Cells2011

    • Author(s)
      Ohtani, K; Vlachojannis, GJ; Koyanagi, M et al.
    • Journal Title

      CIRCULATION RESEARCH

      Volume: 109巻11号 Issue: 11 Pages: 1219-1229

    • DOI

      10.1161/circresaha.111.247304

    • Data Source
      KAKENHI-PROJECT-23591083
  • [Journal Article] Epigenetic repression of endothelial lineage committed genes in pro- angiogenic hematopoietic progenitor cells2011

    • Author(s)
      Ohtani K, Vlachojannis GJ, Koyanagi M, Boeckel JN, Urbich C, Marquez VE, Zeiher AM, & Dimmeler S
    • Journal Title

      Circ Res

      Volume: 109(11) Pages: 1219-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591083
  • [Journal Article] 種々の臨床検査値と末梢血白血球テロメア関連パラメータとの連関の解析2011

    • Author(s)
      前田豊樹,小柳雅孔,尾山純一,樋口義洋,牧野直樹
    • Journal Title

      適応医学

      Volume: 14 Pages: 50-59

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Journal Article] 種々の臨床検査値と末梢血白血球テロメア関連パラメータとの連関の解析.2011

    • Author(s)
      前田豊樹,小柳雅孔,尾山純一,樋口義洋,牧野直樹
    • Journal Title

      適応医学

      Volume: 14 Pages: 50-59

    • Data Source
      KAKENHI-PROJECT-23590885
  • [Presentation] Thrombomodulin Alpha Improved the Cardiac Function but not Hypertrophy in a Transgenic Mouse Model of Inflammatory Cardiomyopathy2013

    • Author(s)
      Higuchi Y, Koyanagi M, Kubota T, Feldman AM, and Makino N.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24591098
  • [Presentation] Epigenetic control of stem cell function2012

    • Author(s)
      Masamichi Koyanagi
    • Organizer
      AHA Scientific Sessions
    • Place of Presentation
      Los Angels, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591083
  • [Presentation] Title;Epigenetic control of stem cell function2012

    • Author(s)
      Masamichi Koyanagi
    • Organizer
      AHA Scientific Sessions
    • Place of Presentation
      Los Angels, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591083
  • [Presentation] Wnt5a increases histone lysine demethylases and induces epigenetic remodeling2011

    • Author(s)
      Masamichi Koyanagi
    • Organizer
      European Epigenomics & Stem Cells-2011 Meetings(招待講演)
    • Place of Presentation
      Paris
    • Data Source
      KAKENHI-PROJECT-23591083
  • [Presentation] Title;Wnt5a increases histone lysine demethylases and induces epigenetic remodeling2011

    • Author(s)
      Masamichi Koyanagi
    • Organizer
      European Epigenomics & Stem Cells-2011 Meetings
    • Place of Presentation
      Paris
    • Data Source
      KAKENHI-PROJECT-23591083
  • 1.  MAEDA Toyoki (30264112)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 2.  MAKINO Naoki (60157170)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 3.  NIIDOME Takuro (20264210)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HIGUCHI Yoshihiro (40404032)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  OYAMA Junich (30359939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  門上 俊明 (40335980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  堀内 孝彦 (90219212)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TSUCHIDA Keiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  稲垣 忍
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  古山 達雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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