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KUBO Kin-ya  久保 金弥

ORCIDConnect your ORCID iD *help
Researcher Number 00329492
Other IDs
Affiliation (Current) 2025: 名古屋葵大学, 健康科学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 名古屋女子大学, 健康科学部, 教授
2017 – 2018: 名古屋女子大学, 家政学部, 教授
2014 – 2016: 星城大学, リハビリテーション学部, 教授
2013 – 2015: 星城大学, 公私立大学の部局等, 教授
2011 – 2013: 星城大学, 健康支援学研究科, 教授 … More
2012: 星城大学, 医療技術学部, 教授
2009 – 2012: 星城大学, リハビリテーション学部, 教授
2006 – 2008: 朝日大学, 歯学部, 講師
2002 – 2004: 朝日大学, 歯学部, 講師 Less
Review Section/Research Field
Principal Investigator
Basic Section 57070:Developmental dentistry-related / Social dentistry / Orthodontics/Pediatric dentistry / 補綴理工系歯学 / Orthodontic/Pediatric dentistry / 補綴理工系歯学
Except Principal Investigator
補綴理工系歯学 / Social dentistry / Orthodontic/Pediatric dentistry / Basic Section 57050:Prosthodontics-related … More / Basic Section 57070:Developmental dentistry-related / Prosthodontics/ Dental materials science and / Basic Section 57080:Social dentistry-related / Applied health science / 補綴理工系歯学 / Orthodontics/Pediatric dentistry / Orthopaedic surgery Less
Keywords
Principal Investigator
妊娠ストレス / 海馬 / SAMP8 / 認知機能 / 空間認知能 / カテコールアミン / ストレス / 咀嚼運動 / 情動障害 / 認知障害 … More / エピジェネティクス / 咀嚼 / 歯 / 歯学 / 老年歯科医学 / デフォルトモードネットワーク / 神経心理的検査 / 脳内ネットワーク / 磁気共鳴画像法 / 神経心理学的検査 / デフォルドモードネットワーク / 口腔環境 / ストレスコーピング / 肥満 / 糖尿病 / insullin resistance / fat / adiposeness / diabetes mellitus / chewing / prenatal stress / Learning ability / Spine / Hippocampus / Occlusal disharmony / 老化促進モデルマウス(SAMP8) / スパイン / 咬合不全 / 情動 / グルココルチコイド / 細胞新生 / 神経発達 / 妊婦ストレス / 神経細胞成長 / コルチコステロン / 神経細胞新生 / 情動行動 / 母胎ストレス / チューイング / 小児歯科学 / ACTH / fMRI / 扁桃体 … More
Except Principal Investigator
ストレス / fMRI / チューイング / 海馬 / 咀嚼刺激 / 咀嚼 / 精神ストレス / 慢性ストレス / 唾液 / 咀嚼物 / 食後血糖 / 自由水 / Memory / Neuronal network / Hippocampus / Mastication / 記憶 / 神経ネットワーク / 咬合 / 偏桃体 / pERK1/2 / 視床下部室傍核 / 扁桃体 / 骨粗鬆症 / 痴呆 / 神経科学 / 認知症 / MMSE / 神経細胞 / 歯の喪失 / 空間認知能 / 高齢者 / メタボリック / 周産期ストレス / 体重 / 高脂肪食 / 妊娠 / 発達障害 / 吸収 / 糖 / 唾液分泌 / 離水 / 流動 / 混合 / 転移がん / GABA / 乳がん / 物性 / 小腸 / ベイジアンネットワーク / 糖の拡散係数 / 飯 / 粘度 / 消化管内容物の移動 / 吸収速度 / 消化管内容物 / グルコースの拡散係数 / 水の拡散係数 / 脳萎縮 / 海馬萎縮 / 口腔環境 / 残存歯数 / Dentures / Elderly / Occulusion / 知的機能維持 / 咬合咀嚼 / 認知 / 義歯 / occulusion / Dementia / 高齢者歯科学 / 学習・記憶 / 大脳皮質 / p-ERK1/2 / p-ERK1/2 / カイニン酸 / p-ERK / Chewing / 骨粗しょう症 / 骨代謝 / ストレスホルモン / 妊娠ストレス / 生後発達障害 / 胎生期ストレス / 海馬新生細胞 / 水迷路テスト / 老化促進モデルマウス / 養育環境 / BDNF / アストロサイト / 細胞分化 / ストレス抑制 / 飼育環境 / 海馬機能 / 飼育環境良好 / 仔マウス / 妊娠中の咬合障害 / 歯学 / 老化 / 社会医学 / 脳の老化 / ブラッシング / 光トポグラフィ / 認知機能 / NIRS / かな拾いテスト / 前頭前野 / 認知記憶 / 口腔ケア / 加齢変化 / 血中グルココルチコイド / 歯の喪失時期 / 情報入力 / シナプトフィジン / 歯の早期喪失 / 老化促進マウス / 歯の長期喪失 / 電子顕微鏡 / 骨形成 / 多核巨細胞 / 炭酸含有アパタイト / 代用骨 / 硫酸化複合糖質 / 新生骨誘起 / 炭酸アパタイト / 骨 / 記憶障害 / マウス / ストレス性記憶障害 / 拘束ストレス / 記憶障害・マウス / 短期記憶 / 記憶力 / 脳年齢 / 高次脳機能 / 咬合咀嚼機能 / ストレス発散 / 小児 Less
  • Research Projects

    (26 results)
  • Research Products

    (180 results)
  • Co-Researchers

    (31 People)
  •  母体の咀嚼運動によるストレス性発達障害胎児期発症の抑制機構の賦活

    • Principal Investigator
      東 華岳
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Elucidation of the suppression mechanism of developmental disorders in children by maternal mastication: analysis of epigenetic modificationsPrincipal Investigator

    • Principal Investigator
      久保 金弥
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Nagoya Women's University
  •  Elucidation of mechanism of metabolic suppression in offspring by perinatal stress during mastication

    • Principal Investigator
      飯沼 光生
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Asahi University
  •  Can salivary secretion be an important modulator of reducing postprandial blood glucose increment?

    • Principal Investigator
      高橋 徹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
      Kanazawa Gakuin University
  •  Chewing attenuates metastasis-promoting effects of chronic stress in mice in

    • Principal Investigator
      Azuma Kagaku
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Elucidation of the neural circuit for the stress suppression mechanism in of chewing and its application to biological stress suppression

    • Principal Investigator
      sasaguri kenichi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Jichi Medical University
  •  Establishment of methodology for controlling postprandial blood sugar to regulate free-water in intestinal contents for clinical application

    • Principal Investigator
      Takahashi Toru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Koriyama Women's University
      Fukuoka Women's University
  •  Effects of chewing on psychological stress-related breast cancer

    • Principal Investigator
      AZUMA Kagaku
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Effect of Oral environment on hippocampal network in the erderlyPrincipal Investigator

    • Principal Investigator
      Kubo kin-ya
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Nagoya Women's University
      Seijoh University
  •  Effects of chewing during prenatal stress on diabetes onset in mouse offspringPrincipal Investigator

    • Principal Investigator
      Kubo Kin-ya
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Nagoya Women's University
      Seijoh University
  •  Effect of oral environment on declining cognitive function of the elderly

    • Principal Investigator
      Onozuka Minoru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Nippon Sport Science University
  •  Maternal chewing during prenatal stress ameliorates stress-induced lower bone mass in adult offspring

    • Principal Investigator
      Kagaku Azuma
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      University of Occupational and Environmental Health, Japan
      Gifu University
  •  Elucidation of intracerebral mechanism of stress reduction effect in amygdala by Chewing

    • Principal Investigator
      Sasaguri Kenichi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Jichi Medical University
      Kanagawa Dental College
  •  Maternal occlusal disharmony produces the learning deficits by the altered hippocampal neurogenesis, enriched enviroment of pups ameliorates the learning deficits

    • Principal Investigator
      Iinuma Mitsuo
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Asahi University
  •  Chewing ameliorates stress-induced osteoporosis in mouse

    • Principal Investigator
      AZUMA Kagaku
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  Maternal chewing prevents stress-induced learning impairment in pupsPrincipal Investigator

    • Principal Investigator
      KUBO Kin-ya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Seijoh University
  •  Oral care-induced activation and reproduction of the functional brain cognitive circuit in the elderly

    • Principal Investigator
      ONOZUKA Minoru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Kanagawa Dental College
  •  Effects of chronic stress of early tooth extraction on hippocampus in senescence-accelerated mice

    • Principal Investigator
      IINUMA Mitsuo
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Asahi University
  •  Protective effect on stress-related memory deficits by chewing

    • Principal Investigator
      WATANABE Kazuko, 渡辺 和子 (渡邊 和子)
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      補綴理工系歯学
    • Research Institution
      Seijoh University
  •  The induction mechanism of new bone formation by sintered carbonate apatite grafted into bone

    • Principal Investigator
      KOGAYA Yasutoku
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      補綴理工系歯学
    • Research Institution
      Asahi University
  •  高齢社会において老年歯科医学が担う社会的重要性を脳科学的に実証する

    • Principal Investigator
      藤田 雅文
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Gifu University
  •  The effect of bite-raised condition on dendritic spine number in hippocampusPrincipal Investigator

    • Principal Investigator
      KUBO Kinya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      補綴理工系歯学
    • Research Institution
      Asahi University
  •  噛むことによる小児のストレス発散の神経科学的解明-磁気共鳴機能画像法による研究-

    • Principal Investigator
      WATANABE Kazuko
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Gifu University
  •  Chewing effects on intelligent activities in the elderly

    • Principal Investigator
      WATANABE Kazuko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      補綴理工系歯学
    • Research Institution
      Gifu University
  •  咀嚼運動によるストレス緩和:fMRI解析Principal Investigator

    • Principal Investigator
      久保 金弥
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      補綴理工系歯学
    • Research Institution
      Asahi University
  •  Chewing effects on intelligent activities

    • Principal Investigator
      ONOZUKA Minoru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      補綴理工系歯学
    • Research Institution
      Kanagawa Dental College
      Gifu University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

  • [Book] Senescence and senescence-related disorders2013

    • Author(s)
      Kubo KY, ChenH, OnozukaM
    • Publisher
      Intech Open Access Publisher
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Book] Senescence and senescence-related disorders2013

    • Author(s)
      Kubo KY, Chen H, Onozuka M
    • Total Pages
      132
    • Publisher
      Intech Open Access Publisher
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Book] Osteoporosis2012

    • Author(s)
      ChenH, Hayashi T, Zhou X, Fujita H, Onozuka M, Kubo KY
    • Publisher
      Intech Open Access Publisher
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Book] Interactions between chewing and brain activity in humans, In Nover Trends in Brain science2008

    • Author(s)
      Onozuka M, Hirano Y, Tachibana A, Kim W, Ono Y, Sasaguri K, Kubo K, Niwa M, Kanematsu K, Watanabe K
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] Maternal chewing alleviates prenatal stress-related neuroinflammation mediated by microglia in the hippocampus of the mouse offspring2023

    • Author(s)
      Hisada C, Kajimoto K, Tsugane H, Iinuma M, Azuma K, Kubo KY
    • Journal Title

      J Prosthodont Res

      Volume: on line Issue: 23 Pages: 5950-5950

    • DOI

      10.3390/cancers14235950

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Journal Article] Deficiency of Wnt10a causes female infertility via the β-catenin/Cys19a1 pathway in mice2022

    • Author(s)
      Zhang J-H, Tasaki T, Tsukamoto M, Wang K-Y, Kubo KY, Azuma K
    • Journal Title

      Int J Med Sci

      Volume: 19 Issue: 4 Pages: 701-710

    • DOI

      10.7150/ijms.71127

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Journal Article] Deletion of Wnt10a is implicated in hippocampal neurodegeneration in mice2022

    • Author(s)
      Zhang J-H, Tasaki T, Tsukamoto M, Wang K-Y, Kubo KY, Azuma K
    • Journal Title

      Biomedicines

      Volume: 10 Issue: 7 Pages: 1500-1500

    • DOI

      10.3390/biomedicines10071500

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Journal Article] Lower Rate of Water Absorption of an Oral Rehydration Solution with Partially Hydrolyzed Guar Gum in Conscious Rats2022

    • Author(s)
      Takahashi Toru、Tokunaga Miki、Okubo Tsutomu、Ozeki Makoto、Kapoor Mahendra P.、Yasukawa Zenta
    • Journal Title

      Nutrients

      Volume: 14 Issue: 20 Pages: 4231-4231

    • DOI

      10.3390/nu14204231

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10321
  • [Journal Article] Maternal chewing improves prenatal stress-induced cognitive deficit and anxiety-like behavior associated with alterations of the apoptotic response and serotonin pathway in mouse offspring.2021

    • Author(s)
      Kajimoto K, Hisada C, Ochi S, Yoshikawa E, Suzuki A, Tsugane H, Zhang J, Iinuma M, Kubo KY, Azuma K
    • Journal Title

      Arch Oral Biol

      Volume: 130 Pages: 105245-105245

    • DOI

      10.1016/j.archoralbio.2021.105245

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065, KAKENHI-PROJECT-18K17270
  • [Journal Article] Chewing Behavior Attenuates the Tumor Progression‐Enhancing Effects of Psychological Stress in a Breast Cancer Model Mouse.2021

    • Author(s)
      Qian Zhou, Masahisa Katano, Jia‐He Zhang, Xiao Liu, Ke‐Yong Wang, Mitsuo Iinuma, Kin‐ya Kubo, Kagaku Azuma.
    • Journal Title

      Brain Sciences

      Volume: 11 Issue: 4 Pages: 479-479

    • DOI

      10.3390/brainsci11040479

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Journal Article] Environmental enrichment improves hypomyelination, synaptic alterations, and memory deficits caused by tooth loss in aged SAMP8 mice.2021

    • Author(s)
      Kin-ya Kubo, Akifumi Ogasawara, Hiroko Tsugane, Mitsuo Iinuma, Toru Takahashi, Kagaku Azuma
    • Journal Title

      Arch Oral Biol

      Volume: 123 Pages: 105039-105039

    • DOI

      10.1016/j.archoralbio.2021.105039

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065, KAKENHI-PROJECT-18K17270
  • [Journal Article] Effects of Maternal Chewing on Prenatal Stress-Induced Cognitive Impairments in the Offspring via Multiple Molecular Pathways2020

    • Author(s)
      Qian Zhou, Ayumi Suzuki, Mitsuo Iinuma, Ke-Yong Wang, Kin-ya Kubo, Kagaku Azuma.
    • Journal Title

      Int J Mol Sci

      Volume: 21 Issue: 16 Pages: 5627-5627

    • DOI

      10.3390/ijms21165627

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Journal Article] Faster short-chain fatty acids absorption from the cecum following polydextrose ingestion increases the salivary immunoglobulin A flow rate in rats2020

    • Author(s)
      Yuko Yamamoto 1 †, Toshiya Morozumi 2 †, Toru Takahashi 3 , Juri Saruta, Masahiro To, Wakako Sakaguchi, Tomoko Shimizu, Nobuhisa Kubota and Keiichi Tsukinoki
    • Journal Title

      Nutrients

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K01863
  • [Journal Article] Tooth loss early in life induces hippocampal morphology remodeling in senescence-accelerated mouse prone 8 (SAMP8) mice2020

    • Author(s)
      Masahisa Katano, Kyoko Kajimoto, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo
    • Journal Title

      Int J Med Sci

      Volume: 17(4) Issue: 4 Pages: 517-524

    • DOI

      10.7150/ijms.40241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05560, KAKENHI-PROJECT-17K11772, KAKENHI-PROJECT-20K10065
  • [Journal Article] Vulnerability to stress in mouse offspring is ameliorated when pregnant dams are provided a chewing stick during prenatal stress.2019

    • Author(s)
      Kubo KY, Suzuki A, Iinuma M, Sato Y, Nagashio R, Ohta E, Azuma K.
    • Journal Title

      Arch Oral Biol

      Volume: 97 Pages: 150-155

    • DOI

      10.1016/j.archoralbio.2018.10.014

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11772, KAKENHI-PUBLICLY-17H05704, KAKENHI-PROJECT-16H05560, KAKENHI-PROJECT-17H07213
  • [Journal Article] Morphological and molecular characterization of the senile osteoporosis in senescence-accelerated mouse prone 6 (SAMP6).2018

    • Author(s)
      Azuma K, Zhou Q, Kubo KY.
    • Journal Title

      Med Mol Morphol

      Volume: 51 Issue: 3 Pages: 139-146

    • DOI

      10.1007/s00795-018-0188-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Journal Article] Yokukansan Ameliorates Hippocampus-Dependent Learning Impairment in Senescence-Accelerated Mouse2018

    • Author(s)
      Azuma K, Toyama T, Katano M, Kajimoto K, Hayashi S, Suzuki A, Tsugane H, Iinuma M, Kubo KY.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 41 Issue: 10 Pages: 1593-1599

    • DOI

      10.1248/bpb.b18-00359

    • NAID

      130007494339

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2018-10-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Journal Article] Chewing during prenatal stress prevents prenatal stress-induced suppression of neurogenesis, anxiety-like behavior and learning deficits in mouse offspring.2018

    • Author(s)
      Kubo KY, Kotachi M, Suzuki A, Iinuma M, Azuma K.
    • Journal Title

      Int J Med Sci

      Volume: 15 Issue: 9 Pages: 849-858

    • DOI

      10.7150/ijms.25281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Journal Article] 骨の老化と加齢性骨粗鬆症の形態学的解析2017

    • Author(s)
      東 華岳, 久保金弥
    • Journal Title

      顕微鏡

      Volume: 52 Pages: 29-34

    • NAID

      130007689240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Journal Article] Maternal occlusal disharmony during pregnancy induces spatial memory deficits associated with the suppression of hippocampal neurogenesis in adult mouse offspring2017

    • Author(s)
      Kondo H, Uchida M, Ichihashi M, Suzuki A, Hayashi S, Iinuma M, Azuma K and Kubo K
    • Journal Title

      Pediatric Dental Journal

      Volume: 27 Issue: 1 Pages: 49-55

    • DOI

      10.1016/j.pdj.2016.12.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11819, KAKENHI-PROJECT-17K11772
  • [Journal Article] Association between mastication, the hippocampus, and the HPA axis: a comprehensive review.2017

    • Author(s)
      Azuma K, Zhou Q, Niwa M, Kubo KY
    • Journal Title

      Int J Mol Sci

      Volume: 18 Issue: 8 Pages: 1867-1867

    • DOI

      10.3390/ijms18081687

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11772, KAKENHI-PROJECT-15K15761
  • [Journal Article] Maternal Active Mastication during Prenatal Stress Ameliorates Prenatal Stress-Induced Lower Bone Mass in Adult Mouse Offspring2017

    • Author(s)
      Azuma K, Ogura M, Kondo H, Suzuki A, Hayashi S, Iinuma M, Onozuka M, Kubo KY
    • Journal Title

      Int J Med Sci

      Volume: 14 Issue: 4 Pages: 348-355

    • DOI

      10.7150/ijms.18298

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462916, KAKENHI-PROJECT-15K15761, KAKENHI-PROJECT-15H05058
  • [Journal Article] Tooth loss early in life suppresses neurogenesis and synaptophysin expression in the hippocampus and impairs learning in mice2017

    • Author(s)
      Kubo KY, Murabayashi C, Kotachi M, Suzuki A, Mori D, Sato Y, Onozuka M, Azuma K, Iinuma M
    • Journal Title

      Arch Oral Biol

      Volume: 74 Pages: 21-27

    • DOI

      10.1016/j.archoralbio.2016.11.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916, KAKENHI-PROJECT-15H05058
  • [Journal Article] Stress-induced galectin-1 influences immune tolerance in the spleen and thymus by modulating CD45 immunoreactive lymphocytes.2017

    • Author(s)
      .Sasaguri K, Yamada K, Narimatsu Y, Oonuki M, Oishi A, Koda K, Kubo KY, Yamamoto T, Kadoya T.
    • Journal Title

      J Physiol Sci.

      Volume: 67(4) Issue: 4 Pages: 489-496

    • DOI

      10.1007/s12576-016-0478-8

    • NAID

      40021238379

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26463124, KAKENHI-PROJECT-15K20459
  • [Journal Article] Maternal chewing during prenatal stress ameliorates stress-induced hypomyelination, synaptic alterations, and learning impairment in mouse offspring2016

    • Author(s)
      Suzuki A, Iinuma M, Hayashi S, Sato Y, Azuma K, Kubo KY
    • Journal Title

      Brain Res

      Volume: 91 Pages: 36-43

    • DOI

      10.1016/j.brainres.2016.09.007

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462916, KAKENHI-PROJECT-15K15761
  • [Journal Article] Novel stress increases hypothalamic-pituitary-adrenal activity in mice with a raised bite2016

    • Author(s)
      Miyake H, Mori D, Katayama T, Fujiwara S, Sato Y, Azuma K, Kubo KY
    • Journal Title

      Arch Oral Biol

      Volume: 68 Pages: 55-60

    • DOI

      10.1016/j.archoralbio.2016.03.020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Hippocampus-dependent spatial memory impairment due to molar tooth loss is ameliorated by an enriched environment.2016

    • Author(s)
      Kondo H, Kurahashi M, Mori D, Iinuma M, Tamura Y, Mizutani K, Shimpo K, Sonoda S, Azuma K, Kubo KY.
    • Journal Title

      Arch Oral Biol.

      Volume: 61 Pages: 1-7

    • DOI

      10.1016/j.archoralbio.2015.10.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350596, KAKENHI-PROJECT-26462916
  • [Journal Article] Effects of Active Mastication on Chronic Stress-Induced Bone Loss in Mice.2015

    • Author(s)
      Azuma K, Furuzawa M, Fujiwara S, Yamada K, Kubo KY
    • Journal Title

      Int J Med Sci

      Volume: 12 Issue: 12 Pages: 952-957

    • DOI

      10.7150/ijms.13298

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Chewing maintains hippocampus-dependent cognitive function.2015

    • Author(s)
      Chen H, Iinuma M, Onozuka M, Kubo KY
    • Journal Title

      Int J Med Sci

      Volume: 12 Issue: 6 Pages: 502-509

    • DOI

      10.7150/ijms.11911

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] 椎体の構造解析による骨粗鬆症の進行と新規骨折の予測2015

    • Author(s)
      東 華岳,周 向栄,藤田広志,小野塚實,久保金弥
    • Journal Title

      Osteoporosis Japan

      Volume: 23 Pages: 337-342

    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Chronic Psychological Stress as a Risk Factor of Osteoporosis2015

    • Author(s)
      Azuma K, Adachi Y, Hayashi H, Kubo KY
    • Journal Title

      Journal of UOEH

      Volume: 37 Issue: 4 Pages: 245-253

    • DOI

      10.7888/juoeh.37.245

    • NAID

      110010015402

    • ISSN
      0387-821X, 2187-2864
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Mastication as a stress-coping behavior.2015

    • Author(s)
      Kubo KY, Iinuma M, Chen H
    • Journal Title

      Biomed Res Int

      Volume: 2015 Pages: 876409-876409

    • DOI

      10.1155/2015/876409

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Tooth loss early in life accelerateds age-remlated bone deterioration in mice.2015

    • Author(s)
      Kurahashi M, Kondo H, Iinuma M, Tamura Y, Chen H, Kubo KY
    • Journal Title

      Tohoku J Exp Med

      Volume: 235 Pages: 29-37

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] The osteocyte plays multiple roles in bone remodeling and mineral homeostasis.2015

    • Author(s)
      Chen H, Senda T, Kubo KY.
    • Journal Title

      Med Mol Morphol

      Volume: 48 Issue: 2 Pages: 61-68

    • DOI

      10.1007/s00795-015-0099-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Chewing maintains hippocampus-dependent cognitive function2015

    • Author(s)
      )Huayue Chen, Mitsuo Iinuma, Minoru Onozuka and Kin-ya Kubo
    • Journal Title

      International Journal of Medical Science

      Volume: 26(3) Pages: 502-509

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24593113
  • [Journal Article] Bone three-dimensional microstructural features of the common osteoporotic fracture sites.2014

    • Author(s)
      Chen H, Kubo KY
    • Journal Title

      World J Orthopedics

      Volume: 5 Issue: 4 Pages: 486-495

    • DOI

      10.5312/wjo.v5.i4.486

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Relationship between the early toothless condition and hippocampal functional morphology2014

    • Author(s)
      Iinuma M, Kondo H, Kurahashi M, Tamura Y, Chen H, Kubo KY.
    • Journal Title

      Anatomy & Physiology

      Volume: 4 Pages: 3-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Journal Article] Relationship between the Early Toothless Condition and HippocampalFunctional Morphology2014

    • Author(s)
      M Iinuma, H Kondo, M Kurahashi, M Onishi, Y Tamura, H Chen and K Kubo
    • Journal Title

      Anatomy and Physiology

      Volume: 4

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24593113
  • [Journal Article] Chewing ameliorates chronic mild stress-induced bone loss in senescence-accelerated mouse (SAMP8), a murine model of senile osteoporosis.2014

    • Author(s)
      Furuzawa M, Chen H, Fujiwara S, Yamada K, Kubo KY
    • Journal Title

      Exp Gerontol

      Volume: 55 Pages: 12-18

    • DOI

      10.1016/j.exger.2014.03.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23592208, KAKENHI-PROJECT-26462916
  • [Journal Article] Chewing ameliorate chronic mild stress-induced bone loss in senescence-accelerated mouse (SAMP8), a murine model of senile osteoporosis2014

    • Author(s)
      Furuzawa M, Chen H, Fujiwara S, Yamada K, Kubo KY
    • Journal Title

      Exp Gerontol

      Volume: 55 Pages: 12-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Age-related changes in trabecular and cortical bone microsctructure.2013

    • Author(s)
      Chen H, Zhou X, Fujita H, Onozuka M, Kubo K
    • Journal Title

      Int J Endocrinol

      Volume: 2013 Issue: 2 Pages: 1-9

    • DOI

      10.5812/ijem.8052

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Age-related changes in trabecular and cortical bone microsctructure2013

    • Author(s)
      Chen H, Zhou X, Fujita H, Onozuka M, Kubo KY
    • Journal Title

      Int J Endocrinol

      Volume: 2013 Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] An update on the structure of the parathyroid gland2013

    • Author(s)
      Chen H, Senda T, Emura S, Kubo KY
    • Journal Title

      The open Anatomy Journal

      Volume: 5 Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] An update on the structure of the parathyroid gland.2013

    • Author(s)
      Chen H, Senda T, Emura S, Kubo K
    • Journal Title

      The open Anatomy Journal

      Volume: 5 Pages: 1-9

    • DOI

      10.2174/1877609401305010001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Combined treatment with a traditional Chinese medicine, Hachimi-jio-gan (Ba-Wei-Di-Huang-Wan) and alendronate improves bone microstructure in ovariectomized rats2012

    • Author(s)
      Chen H, Wu M, Kubo K
    • Journal Title

      J Ethnopharmacol

      Volume: 142 Pages: 80-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Segmental variations in trabecular bone density and microstructure of the spine in senescence-accelerated mouse (SAMP6): A murine model for senile osteoporosis2012

    • Author(s)
      Chen H, Kubo K
    • Journal Title

      Exp Gerontol

      Volume: 47 Pages: 317-322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Gender-related changes in three-dimensional microstructure of trabecular bone at the human proximal tibia with aging2011

    • Author(s)
      Chen H, Washimi Y, Kubo KY, Onozuka M
    • Journal Title

      Histol Histopathol

      Volume: 26 Pages: 563-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Gender-related changes in three-dimensional microstructure of trabecular bone at the human proximal tibia with aging2011

    • Author(s)
      Chen Huayue, Washimi Y, Kubo K, Onozuka M
    • Journal Title

      Histol Histopathol

      Volume: 26 Pages: 563-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390562
  • [Journal Article] 腰椎の外部形状と内部構造の統合解析による骨粗鬆症の解明2011

    • Author(s)
      東 華岳,久保金弥,鷲見雄希,林達郎,周向栄,藤田広志,小野塚實
    • Journal Title

      Osteoporosis Japan

      Volume: 19 Pages: 665-668

    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Gender-related changes in three-dimensional microstructure of trabecular bone at the human proximal tibia with aging2011

    • Author(s)
      Chen H, Washimi Y, Kubo KY, Onozuka M
    • Journal Title

      Histol. Histopathol

      Volume: 26 Pages: 563-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Journal Article] Relationship between light and dark period activity cycles and oral condition in senescence-accelerated mice2011

    • Author(s)
      M.Iinuma, S.Yasui, M.Oonishi, C.Kurata, Y.Ichihashi Y.Tamura, K.Kubo
    • Journal Title

      Okajimas Folia Anat.Jpn

      Volume: 88巻1号 Pages: 29-36

    • NAID

      130004495095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Masticatory function and cognitive function2010

    • Author(s)
      Kin-ya Kubo, et al.
    • Journal Title

      Okajima Folia Anat.Jpn.

      Volume: 87(3) Pages: 135-140

    • NAID

      130004773593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Journal Article] Effects of early tooth extractions on hippocampal GFAP-positive cells in aged senescence accelerated mice2010

    • Author(s)
      M. Iinuma, Y. Hioki, C. Kurata, Y. Ichihashi, Y. Tamura and K. Kubo
    • Journal Title

      Pediatric Dental Journal

      Volume: 20 Pages: 158-164

    • NAID

      10027485870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Effects of early tooth extractions on hippocampal GFAP-positive cells in aged senescence -accelerated mice2010

    • Author(s)
      M.Iinuma, Y.Hioki, C.Kurata, Y.Ichihashi, Y.Tamura, K.Kubo
    • Journal Title

      Pediatric Dental Journal 20

      Pages: 158-164

    • NAID

      10027485870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] T Katayama, H Miyake, S Fujiwara,Y Tamura, Masticatory function and cognitive function2010

    • Author(s)
      K Kubo, Y Ichihashi, C Kurata, M Iinuma, D Mori
    • Journal Title

      Okajima Folia Anat Jpn

      Volume: 87 Pages: 135-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Journal Article] Relationship between light and dark period activity cycles and oral condition in senescence-accelerated mice2010

    • Author(s)
      M. Iinuma, S. Yasui, M. Oonishi, C. Kurata, Y. Ichihashi Y. Tamura and K. Kubo
    • Journal Title

      Okajimas Folia Anat. Jpn

      Volume: 88(1) Pages: 29-36

    • NAID

      130004495095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Occlusion and brain function : mastication as a prevention of cognitive dysfunction2010

    • Author(s)
      Ono Y、Yamamoto T, Kubo KY, et al
    • Journal Title

      J Oral Rehabil 68

      Pages: 236-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] Masticatory function and cognitive function2010

    • Author(s)
      Kubo K, Ichihashi Y, Kurata C, Iinuma M, Mori D, Katayama T, MiyakeH, Fujiwara S and Tamura Y
    • Journal Title

      Okajima Folia Anat Jpn

      Volume: 87(3) Pages: 135-140

    • NAID

      130004773593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Effects of early tooth extractions on hippocampal GFAP positive cells in aged senescence-accelerated mice2010

    • Author(s)
      M.Iinuma, Y.Hioki, C.Kurata, Y.Ichihashi, Y.Tamura, K.Kubo
    • Journal Title

      Pediatric Dental Journal

      Volume: 20(優秀論文賞受賞) Pages: 158-164

    • NAID

      10027485870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Chewing under restraint stress inhibits the stress-induced suppression of cell birth in the dentate gyrus of aged SAMP8 mice.2009

    • Author(s)
      Kubo KY, Sasaguri K, Ono Y, Yamamoto T, Takahashi T, Watanabe K, Karasawa N, Onozuka M
    • Journal Title

      Neurosci Lett 463

      Pages: 109-113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] Effects of early loss on the hippocampus in senescence-accelerated mice2009

    • Author(s)
      Y.Hioki, M.Iinuma, C.Kurata, Y.Ichihashi, Y.Tamura, K.Kubo
    • Journal Title

      Pediatric Dental Journal 19巻

      Pages: 196-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Effects of early loss on the hippocampus in senescence-accelerated mice2009

    • Author(s)
      Y. Hioki, M. Iinuma, C. Kurata, Y. Ichihashi, Y. Tamura and K. Kubo
    • Journal Title

      Pediatric Dental Journal

      Volume: 19 Pages: 196-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Effects of early loss on the hippocampus in senescence-accelerated mice2009

    • Author(s)
      Y.Hioki, M.Iinuma, C.Kurata, Y.Ichihashi, Y.Tamura, K.Kubo
    • Journal Title

      Pediatric Dental Journal 19

      Pages: 196-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] The bite-raised condition in aged SAMP8 mice induces dendritic spine changes in the hippocampal region2008

    • Author(s)
      Kubo K, Kojo A, Yamamoto T, Onozuka M
    • Journal Title

      Neurosci Lett 441

      Pages: 141-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] The bite-raised condition in aged SAMP8 mice induces dendric spine changes in the hippocampal region2008

    • Author(s)
      Kin-ya Kubo, et. al.
    • Journal Title

      Neuroscience Letters (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] Changes in GFAP-immunoreactive astrocytes-induced by the bite-raised condition in aged SAMP8 mice2008

    • Author(s)
      Ichihashi Y, Arakawa Y, Iinuma M, Tamura Y, Kubo K, Iwaku F, Takahashi T, Karasawa N, Nagatsu I, Onozuka M
    • Journal Title

      Biogenic Amines 22

      Pages: 39-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] 老化促進マウス(SAMP1)の経管栄養飼育が中枢に及ぼす影響2008

    • Author(s)
      飯沼光生, 西田淑江, 市橋幸子, 荒川容子, 田村康夫, 久保金弥
    • Journal Title

      日本歯科医師会雑誌 : 第21回日本歯科医学会総会抄録集 61巻5号

      Pages: 99-99

    • Data Source
      KAKENHI-PROJECT-20592420
  • [Journal Article] Occiusal disharmony induces spatial memory impairment and hippocampal neuron degeneration.2007

    • Author(s)
      Kin-ya Kubo
    • Journal Title

      Neurosci. Lett. 414

      Pages: 188-191

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] Occlusal disharmony attenuates glucocortical negative feedback in aged SAMP8 mice2007

    • Author(s)
      Ichihashi Y, Arakawa Y, Iinuma M, Tamura Y, Kubo K, Iwaku F, Sato Y, Onozuka M
    • Journal Title

      Neurosci Lett 427

      Pages: 71-76

    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] Occlusal disharmony induces spatial memory impairment and hippocam pal neuron degeneration via stress in SAMP82007

    • Author(s)
      Kubo K, et. al.
    • Journal Title

      Neurosci Lett 14

      Pages: 188-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] Involvement of glucocorticoid response in hippocampal activities in aged SAMPS mice with occlusal disharmony.2007

    • Author(s)
      Kin-ya Kubo
    • Journal Title

      Biogenic Amines (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] The corticosterone synthesis inhibitor metyrapone prevents bite-raised induced impairment of hippocampal function in aged senescence-accerelated prone mice(SAIVIP8).2007

    • Author(s)
      Kin-ya Kubo
    • Journal Title

      Biogenic Amines (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] Occlusal sisharmony induces spatial memory impairment and hippocampal neuron degeneration via stress in SAMP8 mice2007

    • Author(s)
      Kin-ya Kubo, et al.
    • Journal Title

      Neuroscience Letters 414(2)

      Pages: 188-191

    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] The molarless condition in aged SAMP8 mice reduces hippocampal inhibition of hypothalamic-pituitary-adrenal axis.2007

    • Author(s)
      Kin-ya Kubo
    • Journal Title

      Biogenic Amines (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] Occlusal disharmony induces spatial memory impairment and hippocampal neuron degeneration via stress in SAMP8 mice.2007

    • Author(s)
      Kubo KY, Yamada Y, Iinuma M, Iwaku F, Tamura Y, Watanabe K, Nakamura H, Onozuka M.
    • Journal Title

      Neurosci Lett. 414

      Pages: 188-191

    • Data Source
      KAKENHI-PROJECT-19390493
  • [Journal Article] Occlusal disharmony induces spatial memory impairment and hippocampal neuron degeneration via stress in SAMP8 mice2007

    • Author(s)
      Kin-ya Kubo, et. al.
    • Journal Title

      Neuroscience Letters 414

      Pages: 188-191

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] The bite-raised condition in aged SAMP8 mice induces dendritic spine changes in the hippocampal region.2007

    • Author(s)
      Kin-ya Kubo
    • Journal Title

      Neurosci. Lett. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] Occlusal disharmony induces spatial memory impairment and hippocam-Pal neuron degeneration via stress in SAMP8 mice2007

    • Author(s)
      Kin-ya Kubo, et. al.
    • Journal Title

      Neuroscience Letters 414

      Pages: 188-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Journal Article] Involvement of glucocorticoid response in hippocampal activities in aged SAMP8 mice with occlusal disharmony

    • Author(s)
      Kin-ya Kubo, et. al.
    • Journal Title

      Biogenic Amines (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Presentation] Maternal chewing during prenatal stress improves microglia-mediated neuroinflammation2022

    • Author(s)
      Kajimoto K, Hisada C, Ochi S, Tsugane H, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] Effects of masticatory movements during prenatal stress on hippocampal dendrites2022

    • Author(s)
      Ochi S, Yoshikawa E, Katano M, Suzuki A, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 母マウスの咀嚼運動が仔の海馬のミクログリアに及ぼす影響2022

    • Author(s)
      梶本京子、杉本勘太、久田智詠、越智鈴子、津金裕子、飯沼光生、斎藤一誠、東 華岳、久保金弥
    • Organizer
      第60回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 歯の早期喪失が海馬のBDNF発現と情動障害に及ぼす影響2022

    • Author(s)
      津金裕子、尾辻 渉、片野雅久、越智鈴子、梶本京子、鈴木あゆみ、斎藤一誠、飯沼光生、東 華岳、久保金弥
    • Organizer
      第60回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 乳がんの進行に対するストレスと咀嚼刺激の影響2021

    • Author(s)
      東 華岳、周 倩、張 家赫、久保金弥
    • Organizer
      第53回日本臨床分子形態学会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] Effects of maternal chewing during prenatal stress on microglia-mediated neuroinflammation in the hippocampus of the offspring2021

    • Author(s)
      Hisada C, Kajimoto K, Tsukane H, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 豊かな環境は老化促進モデルマウス(SAM)P8の歯の喪失によって誘発される髄鞘低形成、シナプス低形成および記憶障害を改善する2021

    • Author(s)
      久田智詠、吉川英里、梶本京子、津金裕子、飯沼光生、東 華岳、久保金弥
    • Organizer
      第36回老化促進モデルマウス(SAM)学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 妊娠母体の咀嚼運動が仔のLPS投与におけるミクログリアの活性化に及ぼす影響2021

    • Author(s)
      久田智詠、市橋豊雄、市橋幸子、津金裕子、林 櫻子、飯沼光生、斎藤一誠、東 華岳、久保金弥
    • Organizer
      第59回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] Long-term tooth loss affects the hippocampal neuronal dendrite morphology in SAMP8 mice2021

    • Author(s)
      Yoshikawa E, Suzuki A, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] The potential role of early tooth loss in the pathogenesis of the App knock-in mouse model2021

    • Author(s)
      Ochi S, Saitoh T, Saido T, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 歯の早期喪失がアルツハイマー病の発症に及ぼす影響.2020

    • Author(s)
      越智鈴子、久田智詠、鈴木あゆみ、飯沼光生、東 華岳、久保金弥
    • Organizer
      第58回日本小児歯科学会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 妊娠母体の咀嚼が仔マウス海馬の構造と機能に及ぼす影響2020

    • Author(s)
      Qian Zhou、王 克鏞、林 春樹、安達泰弘、久保金弥、東 華岳
    • Organizer
      第125回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 妊娠母体の咀嚼が仔マウス海馬の構造と機能に及ぼす影響2020

    • Author(s)
      Qian Zhou, 王 克鏞, 林 春樹, 安達泰弘, 久保金弥, 東  華岳
    • Organizer
      第125回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 歯の早期喪失が海馬の体積に及ぼす影響.2020

    • Author(s)
      吉川英里、松田成彦、岡野 哲、林 櫻子、飯沼光生、東 華岳、久保金弥
    • Organizer
      第58回日本小児歯科学会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 歯の早期喪失が老化促進マウス(SAMP8)の海馬体積に影響する2020

    • Author(s)
      吉川英里、越智鈴子、久田智詠、片野雅久、梶本京子、林 櫻子、 鈴木あゆみ、津金裕子、飯沼光生、東 華岳、久保金弥
    • Organizer
      第35回老化促進モデルマウス(SAM)学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] Long-term tooth loss affects the hippocampal volume and oligodendrocytes in SAMP8 mice.2020

    • Author(s)
      Eri Yoshikawa, Suzuko Ochi, Chie Hisada, Masahisa Katano, Kyoko Kajimoto, Sakurako Hayashi, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K10065
  • [Presentation] 妊娠母体の咀嚼が新生仔の海馬の神経細胞数とアストロサイトに及ぼす影響2019

    • Author(s)
      片野雅久、市橋幸子、宋元政文、越智鈴子、鈴木あゆみ、津金裕子、飯沼光生、東 華岳、久保金弥
    • Organizer
      第57回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 歯の喪失が老化促進モデルマウス(SAMP8)海馬の微細構造に及ぼす影響2019

    • Author(s)
      片野雅久、越智鈴子、久田智詠、吉川英里、梶本京子、林櫻子、鈴木あゆみ、津金裕子、 飯沼光生、東 華岳、久保金弥
    • Organizer
      第34回老化促進モデルマウス(SAM)学会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 妊娠母体のストレス下の咀嚼運動は仔の肥満および糖尿病の発症を抑制する2019

    • Author(s)
      林 櫻子、谷 向務、入江庸介、梶本京子、吉川英里、久田智詠、飯沼光生、山田久美子、東 華岳、久保金弥
    • Organizer
      第57回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Maternal chewing during prenatal stress alleviates stress-induced diabetes in mouse offspring.2019

    • Author(s)
      Sakurako Hayashi, Kyoko Kajimoto, Masahisa Katano, Hiroko Tsugane, Kumiko Yamada, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo
    • Organizer
      The 27th IAPD Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Enriched environment ameliorates hypomyelination and synaptic alterations induced by tooth loss2019

    • Author(s)
      Chie Hisada, Suzuko Ochi, Eri Yoshikawa, Sakurako Hayashi, Hiroko Tsugane, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo
    • Organizer
      The 27th IAPD Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Prenatal stress-induced obesity and diabetes in mouse offspring is prevented by allowing pregnant dams to chew on a stick.2019

    • Author(s)
      Sakurako Hayashi, Masahisa Katano, Kyoko Kajimoto, Suzuko Ochi, Chie Hisada, Eri Yoshikawa, Hiroko Tsugane, Kumiko Yamada, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 妊娠ストレスと咀嚼運動による胎盤と仔マウス海馬のストレス関連因子の発現変化2019

    • Author(s)
      Qian Zhou, 林春樹、安達泰弘、久保金弥、東 華岳
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 抑肝散による認知機能障害抑制効果の検討2018

    • Author(s)
      梶本京子、外山達也、西英光、林櫻子、越智鈴子、近藤裕子、飯沼光生、山田久美子、 東 華岳、久保金弥
    • Organizer
      第56回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Tooth loss induces morphological changes in hippocampal glial cells2018

    • Author(s)
      Hiroko Kondo, Ayumi Suzuki, Sakurako Hayashi, Kyoko Kajimoto, Masahisa Katano, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo
    • Organizer
      96th general session & exhibition of the International Association for Dental Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Maternal chewing during prenatal stress in mice ameliorates stress-induced impairment of serotoninergic system in the adult offspring.2018

    • Author(s)
      Kajimoto K, Kondo H, Suzuki A, Hayashi S, Katano M, Iinuma M, Azuma K, Kubo KY.
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 歯の早期喪失が海馬におけるミクログリアの発現に及ぼす影響.2018

    • Author(s)
      近藤裕子、久田智詠、吉川英里、梶本京子、片野雅久、鈴木あゆみ、飯沼光生、東 華岳、久保金弥
    • Organizer
      第56回日本小児歯科学会大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Maternal chewing ameliorates prenatal stress-induced hippocampal impairment in adult offspring2018

    • Author(s)
      Ayumi Suzuki, Hiroko Kondo, Mitsuo Iinuma, Kagaku Azuma, Kin-ya Kubo.
    • Organizer
      96th general session & exhibition of the International Association for Dental Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 歯の早期喪失がSAMP8マウスにおける海馬神経細胞の微細構造に及ぼす影響2018

    • Author(s)
      東 華岳、安達泰弘、林春樹、Qian Zhou,久保金弥
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 歯の早期喪失がSAMP8マウスにおける海馬神経細胞の微細構造に及ぼす影響2018

    • Author(s)
      東 華岳、安達泰弘、林春樹、Qian Zhou、久保金弥
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 妊娠ストレス中のチューイングはSAMP6仔の骨代謝に及ぼす影響.2018

    • Author(s)
      梶本京子、近藤裕子、鈴木あゆみ、林 櫻子、片野雅久、飯沼光生、東 華岳、久保金弥
    • Organizer
      第33回老化促進モデルマウス(SAM)学会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Maternal chewing during prenatal stress ameliorates stress-induced diabetes in adult offspring.2018

    • Author(s)
      Hayashi S, Kondo H, Suzuki A, Kajimoto K, Katano M, Yamada K, Sato Y, Iinuma M, Azuma K, Kubo KY.
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 老化促進モデルマウスSAMP8に対する抑肝散の効果:空間学習記憶と海馬微細構造の解析2017

    • Author(s)
      東 華岳、久保金弥
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Molar tooth loss early in life affects the hippocampal neuronal ultrastructure in SAMP8 mice.2017

    • Author(s)
      Hayashi S, Suzuki A, Kondo H, Katano M, Kajimoto K, Iinuma M, Azuma K, Kubo KY.
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 加齢に伴う海馬機能の低下に対する抑肝散の影響:SAMP8を用いた検討2017

    • Author(s)
      林 櫻子、片野雅久、梶本京子、鈴木あゆみ、近藤裕子、飯沼光生、東 華岳、久保金弥
    • Organizer
      第32回老化促進モデルマウス(SAM)学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] Maternal chewing during prenatal stress ameliorates stress-induced HPA axis disturbance in adult offspring.2017

    • Author(s)
      Suzuki A, Hayashi S, Kondo H, Katano M, Kajimoto K, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K11772
  • [Presentation] 老化促進モデルマウスSAMP8に対する抑肝散の効果:空間学習記憶と海馬微細構造の解析2017

    • Author(s)
      東 華岳、久保金弥
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Place of Presentation
      長崎大学坂本キャンパス(長崎県・長崎市)
    • Year and Date
      2017-03-28
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] 歯の早期喪失が海馬の髄鞘形成に及ぼす影響:SAMP8を用いた検討2016

    • Author(s)
      鈴木あゆみ、林櫻子、近藤裕子、村林知香、飯沼光生、東 華岳、久保金弥
    • Organizer
      第31回老化促進モデルマウス(SAM)研究協議会研究発表会
    • Place of Presentation
      京都大学医学部芝欄会館(京都府・京都市)
    • Year and Date
      2016-07-09
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] Maternal chewing during prenatal stress ameliorates stress-induced synaptic and myelin alterations in the hippocampus in adult pups.2016

    • Author(s)
      Suzuki A, Hayashi S, Kondo H, Ogura M, Murabayashi C, Kotachi M, Iinuma M, Azuma K, Kubo KY
    • Organizer
      10th Biennial conference of the pediatric dentistry association of asia
    • Place of Presentation
      Tokyo Dome Hotel(東京都・文京区)
    • Year and Date
      2016-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] Maternal chewing during prenatal stress ameliorates stress-induced vulnerability of the brain to novel stress in the adult pups in mice2016

    • Author(s)
      Suzuki A, Hayashi S, Kondo H, Murabayashi C, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] マイクロCTによる骨の三次元微細構造解析2016

    • Author(s)
      東 華岳、久保金弥
    • Organizer
      日本顕微鏡学会第72回学術講演会
    • Place of Presentation
      仙台国際会議場(宮城県・仙台市)
    • Year and Date
      2016-06-14
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] 歯の喪失により惹起される海馬機能障害は豊かな飼育環境により改善される2015

    • Author(s)
      近藤裕子、倉橋実里、鈴木あゆみ、小刀見佳、村林知香、森大輔、飯沼光生、田村康夫、久保金弥。
    • Organizer
      第53回日本小児歯科学会
    • Place of Presentation
      広島
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-24593113
  • [Presentation] Maternal chewing during prenatal stress ameliorates stress-induced deficits in myelin formation in the hippocampus in adult pups2015

    • Author(s)
      Suzuki A, Kotachi M, Murabayashi C, Kondo H, Kurahashi M, Iinuma M, Azuma K, Kubo KY
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] Masticatory activity affects bone remodeling in mice.2015

    • Author(s)
      Chen H, Senda T, Kubo KY
    • Organizer
      13th congress of the international society of bone morphometry
    • Place of Presentation
      Tokyo Garden Palace Hotel(東京都文京区)
    • Year and Date
      2015-04-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] 歯の喪失により惹起される海馬機能障害は豊かな飼育環境により改善される.2015

    • Author(s)
      近藤裕子、倉橋実里、鈴木あゆむ、村林知香、森 大輔、飯沼光雄、田村康夫、 陳 華岳、久保金弥
    • Organizer
      第30回老化促進モデルマウス(SAM)研究協議会研究発表会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜県岐阜市)
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] Maternal occlusal disharmony suppresses cell proliferation in the hippocampus of pups2015

    • Author(s)
      Mitsuo Iinuma, Sakae Mori, Hiroko Kmondo, Chika Murabayashi, Yasuo Tamura and Kin-ya Kubo
    • Organizer
      25th Congress of International Association of Pediatric Dentistrt
    • Place of Presentation
      Glasgow,UK
    • Year and Date
      2015-07-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593113
  • [Presentation] 飼育環境が歯の喪失により惹起された空間認知能に与える影響2014

    • Author(s)
      近藤裕子、尾辻渉、倉橋実里、大西見佳、鈴木あゆみ、村林知香、飯沼光生、田村康夫、森大輔、久保金弥
    • Organizer
      第52回日本小児歯科学会
    • Place of Presentation
      東京、品川区立総合区民会館
    • Year and Date
      2014-05-16
    • Data Source
      KAKENHI-PROJECT-24593113
  • [Presentation] 老化促進マウスSAMP6における骨細胞・骨細管系の構造解析2014

    • Author(s)
      陳 華岳、久保金弥、千田隆夫
    • Organizer
      第119回日本解剖学会
    • Place of Presentation
      自治医科大学
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 老化促進マウスSAMP6における骨細胞・骨細管系の構造解析2014

    • Author(s)
      陳華岳、久保金弥、千田隆夫
    • Organizer
      第119回日本解剖学会・全国学術集会
    • Place of Presentation
      自治医科大学
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 老化促進マウスSAMP6におけるJ骨構造の変化2013

    • Author(s)
      陳華岳、久保金弥、千田隆夫
    • Organizer
      第118回日本解剖学会・全国学術集会
    • Place of Presentation
      かがわ国際会議場
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] チューイングは母体ストレスの認知機能障害を抑制する2013

    • Author(s)
      久保金弥、佐藤和彦、小萱康徳、陳華岳
    • Organizer
      第118回日本解剖学会・全国学術集会
    • Place of Presentation
      かがわ国際会議場
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Chewing during chronic stress ameliorates stress-induced bone loss2013

    • Author(s)
      Furuzawa M, Mori D, Miyake H, Katayama T,Fujiwara S, Chen H, Kubo KY
    • Organizer
      Annual meeting of the International Association for Dental Research
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Effects of maternal occlusal stress on hippocampal neurogenesis in SAM mouse pups2013

    • Author(s)
      M Iinuma, H Kondo, M Kurahashi, M Onishi, Y Tamura and K Kubo
    • Organizer
      24th International Association of Pediatric Dentistry
    • Place of Presentation
      韓国ソウルcoex
    • Data Source
      KAKENHI-PROJECT-24593113
  • [Presentation] Maternal chewing prevents stress-induced anxiety-like behavior2013

    • Author(s)
      M Onishi, M Kurahashi, H Kondo, C Kurata, M Iinuma, Y Tamura, D Mori, K Kubo
    • Organizer
      IADR
    • Place of Presentation
      アメリカ(シアトル)
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] 歯の早期喪失が加齢による骨の脆弱に及ぼす影響2013

    • Author(s)
      倉橋実里、市橋幸子、近藤裕子、大西見佳、鈴木あゆみ、村林知香、森大輔、飯沼光生、田村康夫、陳華岳、久保金弥
    • Organizer
      第32回日本小児歯科学会中部地方会
    • Place of Presentation
      朝日大学
    • Year and Date
      2013-11-04
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] チューイングがストレス性骨粗鬆症に及ぼす影響2013

    • Author(s)
      古澤学, 森大輔, 三宅秀和, 片山祐, 三村真一 ,小木曽明, 藤原周, 陳華岳, 久保金弥
    • Organizer
      第122回日本補綴学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2013-05-18
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Chewing during prenatal stress ameliorates stress-induced suppression of brain-derived neurotrophic factor expression in the hippocampus2013

    • Author(s)
      Kin-ya Kubo
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] 慢性ストレスおよびチューイングによるストレス緩和によるマウス骨の構造2013

    • Author(s)
      陳華岳、千田隆夫、久保金弥
    • Organizer
      第73回日本解剖学会中部支部学術集会
    • Place of Presentation
      山梨大学甲府キャンパス
    • Year and Date
      2013-10-15
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] チューイングは母胎ストレス性の認知機能障害を抑制する2013

    • Author(s)
      久保金弥
    • Organizer
      第118回日本解剖学会全国学術集会
    • Place of Presentation
      かがわ国際会議場
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] The effects of chewing on the chronic mild stress-induced bone loss in mice2013

    • Author(s)
      Chen H, Senda T, Kubo KY
    • Organizer
      IOF regionals 4th Asia-Pacific osteoporosis meeting
    • Place of Presentation
      Hong kong, Convention and ExhibitionCenter, China
    • Year and Date
      2013-12-13
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 加齢による骨量の減少は骨の種類によって異なる:マイクロCTによるヒト海綿骨の三次元微細構造観察2012

    • Author(s)
      陳華岳、久保金弥、千田隆夫
    • Organizer
      第117回日本解剖学会・全国学術集会
    • Place of Presentation
      山梨大学
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Maternal chewing prevents stress-induced developmental impairment of catecholaminergic neurons2012

    • Author(s)
      Kin-ya Kubo
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] 咀嚼運動が母胎ストレス性情動障害に及ぼす影響2012

    • Author(s)
      大西見佳、倉橋実里、近藤裕子、倉田知香、市橋幸子、飯沼光生、田村康夫、久保金弥
    • Organizer
      小児歯科学会第50回記念大会
    • Place of Presentation
      東京フォーラム
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] チューイングによる母胎ストレス性の認知機能障害を抑制する2012

    • Author(s)
      久保金弥、佐藤和彦、小萱康徳、東華岳
    • Organizer
      第118回日本解剖学会全国学術集会
    • Place of Presentation
      かがわ国際会議場
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] Chewing during stress suppresses stress-induced activity in thehypothalamic-pituitary-adrenal axis2012

    • Author(s)
      M Onishi, M Kurahashi, H Kondo, C Kurata, Y Ichihashi, M Iinuma, Y Tamura, D Mori,M Onozuka, K Kubo
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] チューイングは胎児ストレス性のカテコールアミンニューロンの発達障害を抑制する2012

    • Author(s)
      久保金弥、大西見佳、森大輔、飯沼光生、田村康夫、陳華岳、唐沢延行、小野塚実
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 椎骨の骨量の加齢変化に関するヒトとサルとの相違2012

    • Author(s)
      陳華岳、久保金弥、西村剛、高井正成、千田隆夫
    • Organizer
      第72回日本解剖学会中部支部学術集会
    • Place of Presentation
      岐阜じゅうろくプラザ
    • Year and Date
      2012-10-14
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Maternal chewing prevents stress-induced developmental impairment of catechol- aminergic neurons2012

    • Author(s)
      K Kubo, M Onishi, D Mori, M Iinuma, Y Tamura, H Chen, N Karasawa, M Onozuka
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] 加齢による骨量の減少は骨の種類によって異なる-マイクロCTによるヒト海綿骨の三次元微細構造観察-2012

    • Author(s)
      陳 華岳,久保金弥,千田隆夫
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      山梨大学
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Maternal chewing prevents stress- induced anxiety-like behavior and learn- ing impairment2011

    • Author(s)
      M Onishi, C Kurata, Y Ichihashi, M Iinuma, Y Tamura, D Mori, N Karasawa, M Onozuka ,KKubo
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] Effects of prolonged toothless condition on synaptogenesis in the hippocampus of SAMP8 mice2011

    • Author(s)
      C Kurata, M Onishi, Y Ichihashi, M Iinuma, D Mori, M Onozuka, K Kubo
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Effects of prolonged toothless condition on synaptogenesis in the hippocampus of SAMP8 mice2011

    • Author(s)
      C Kurata, M Onishi, Y Ichihashi, M Iinuma, D Mori, M Onozuka and K Kubo
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] 小児の歯の喪失が海馬のSynaptophysin発現に及ぼす影響2011

    • Author(s)
      倉田知香、小山和彦、大西見佳、市橋幸子、飯沼光生、田村康夫、久保金弥
    • Organizer
      第49回日本小児歯科学会大会
    • Place of Presentation
      いわて県民情報交流センター(岩手県)
    • Year and Date
      2011-11-29
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] ストレスの緩和に及ぼすチューイングの効果-fMRIによる研究-2011

    • Author(s)
      水野潤造, 丹羽政美, 久保金弥, 湯山徳行, 小野塚實
    • Organizer
      第34回日本神経科学学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21390562
  • [Presentation] 小児の歯の喪失が海馬のSynaptophysin発現に及ぼす影響2011

    • Author(s)
      倉田知香、小山和彦、大西見佳、市橋幸子、飯沼光生、田村康夫、久保金弥
    • Organizer
      第49回日本小児歯科学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      2011-11-29
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Prolonged molarless condition exacerbates aged-related deterioration of the hippocampus in SAMP8 mice2011

    • Author(s)
      M.Iinuma, H.Nakahara, M.Ito, S.Mori, Y.Tamura, K.Kubo
    • Organizer
      24th IAPD Meeting
    • Place of Presentation
      アテネ(ギリシア)
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Prolonged molarless condition exacerbates aged-related deterioration of the hippocampus in SAMP8 mice2011

    • Author(s)
      M. Iinuma, H. Nakahara, M. Ito, S. Mori, Y. Tamura and K. Kubo
    • Organizer
      第24回国際小児歯科学会
    • Place of Presentation
      アテネ、ギリシア
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Maternal chewing rescues stress-induceddeterioration of learning-stimulated hippocampal neurogenesis in her baby2010

    • Author(s)
      K Kubo, N Karasawa, M Onozuka
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] Prolonged toothless condition progresses aging processes in the hippocampus2010

    • Author(s)
      K. Kurata, Y. Tamura, M. Iinuma, Y. Ichihash and K. Kubo
    • Organizer
      第88回国際歯科学会
    • Place of Presentation
      バルセロナ、スペイン
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Prolonged toothless condition progresses aging processes in the hippocampus2010

    • Author(s)
      K.Kurata, Y.Tamura,M.Iinuma, Y.Ichihashi, K.Kubo
    • Organizer
      88th IADR Meeting
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Maternal chewing rescues stress-induced deterioration of learning-stimulated hippocampal neurogenesis in her baby2010

    • Author(s)
      Kin-ya Kubo, et al.
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      Kobe Convention Center
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-22390395
  • [Presentation] Effects of tooth extractions on hippocampus in senescence-accelerated mice2009

    • Author(s)
      M. Iinuma, Y. Hioki, Y. Ichihashi, Y. Tamura and K. Kubo
    • Organizer
      第22回国際小児歯科学会
    • Place of Presentation
      ミュンヘン、ドイツ
    • Year and Date
      2009-06-12
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Long-lasting toothless condition progresses aging processes in the hippocampus2009

    • Author(s)
      IinumaM., KurataC., IchihashiY., TamuraY., KuboK., OnozukaM.
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Chewing is involved in cell generation in the aged hippocampus dentate gyrus2009

    • Author(s)
      Kubo KY, Sasaguri K, et al
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Presentation] Chewing is involved in cel generation in the aged hippocampus dentate gurus2009

    • Author(s)
      Kubo K, Sasaguri, KI, Kimura K, Watanabe K, Onozuka M
    • Organizer
      第32回神経科学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Presentation] Long-lasting toothless condition progresses aging processes in the hippocampus2009

    • Author(s)
      M. Iinuma, C. Kurata, Y. Ichihashi, Y. Tamura, K. Kubo and M. Onozuka
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Occlusal disharmony causes a decrease in hippocampal spines.2008

    • Author(s)
      Kin-ya Kubo
    • Organizer
      The 31st Annual Meeting of the Japan, Neuroscience Society
    • Place of Presentation
      Tokyo Forum
    • Year and Date
      2008-07-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Presentation] 歯の早期喪失は海馬の老化を促進させる-老化促進モデルマウスを用いた研究2008

    • Author(s)
      荒川容子, 市橋幸子, 倉田知香, 飯沼光生, 田村康夫, 久保金弥
    • Organizer
      第46回日本小児歯科学会大会
    • Place of Presentation
      さいたま市大宮ソニックシティー
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-20592420
  • [Presentation] Chewing-related neuronal mechanism under stress condition2007

    • Author(s)
      Kim W, Tachibana A, Otsuka T, Hirano Y, Kubo KY, Ono Y, Nakamura H, Karasawa N, Onozuka M, Watanabe K
    • Organizer
      30回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2007-09-11
    • Data Source
      KAKENHI-PROJECT-19390493
  • [Presentation] Involvement of glucocorticoid response in hippocampal changes in aged SAMP8 mice with occlusal disharmony.2007

    • Author(s)
      Kin-ya Kubo
    • Organizer
      The 30th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Pacifico Yokohama
    • Year and Date
      2007-09-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Presentation] Involvement of glucocorticoid response in hippocampal changes in aged SAMP8 mice with occlusal disharmony2007

    • Author(s)
      Kin-ya Kubo, et. al.
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-09-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Presentation] Effect of abnormal occlusal on the hippocampus in SAMP8 mice.2006

    • Author(s)
      Kin-ya Kubo
    • Organizer
      The 29th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference Hall
    • Year and Date
      2006-07-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592153
  • [Presentation] チューイングは胎児ストレス性のカテコールアミンニューロンの発達障害を抑制する

    • Author(s)
      久保金弥, 大西見佳, 森大輔, 飯沼光生, 田村康夫, 陳 華岳,唐沢延行, 小野塚實
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 椎骨の骨量の加齢変化に関するヒトとサルとの相違

    • Author(s)
      陳 華岳,久保金弥、西村剛、高井正成、千田隆夫
    • Organizer
      第72回日本解剖学会中部支部学術集会
    • Place of Presentation
      岐阜じゅうろくプラザ
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 老化促進マウスSAMP6における骨構造の変化

    • Author(s)
      陳 華岳,久保金弥,千田隆夫
    • Organizer
      第118回日本解剖学会
    • Place of Presentation
      かがわ国際会議場
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 妊娠中の母体ストレスマウスのチューイングが新生仔マウスの骨構造に及ぼす影響

    • Author(s)
      陳 華岳,千田隆夫,久保金弥
    • Organizer
      第120回日本解剖学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] 加齢による骨量の減少は骨の種類によって異なる:マイクロ CT によるヒト海綿骨の三次元微細構造観察

    • Author(s)
      陳 華岳,久保金弥,千田隆夫
    • Organizer
      第117回日本解剖学会総会
    • Place of Presentation
      山梨大学
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] 豊かな飼育環境は歯の喪失によって惹起される学習障害を改善する

    • Author(s)
      近藤 裕子、倉橋 実里、鈴木 あゆみ、大西 見佳、村林 知香、飯沼 光生、森 大輔、陳 華岳、久保 金弥
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] チューイングは母胎ストレス性の認知機能障害を抑制する

    • Author(s)
      久保金弥,佐藤和彦,小萱康徳,陳 華岳
    • Organizer
      第118回日本解剖学会
    • Place of Presentation
      かがわ国際会議場
    • Data Source
      KAKENHI-PROJECT-23592208
  • [Presentation] Effects of chewing on stress-induced bone loss

    • Author(s)
      Furuzawa M, Chen H, Fujiwara S, Kubo KY
    • Organizer
      38th annual conference of the European prosthodontic association
    • Place of Presentation
      Wyndham Istanbul Kalamis Marina, Istanbul, TURKEY
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26462916
  • [Presentation] Effects of early tooth loss on Age-dependent changes in three-dimensional microstructure of trabecular bones in accelerated senescence mouse SAMP8

    • Author(s)
      Kurahashi M, Kondo H, Suzuki A, Onishi M, Murabayashi C, Iinuma M,Tamura Y, Furuzawa M, Chen H, Kubo K
    • Organizer
      10th Biennial conference of the pediatric dentistry association of Asia in conjunction with 54th annual conference of the Japanese society of pediatric dentistry
    • Place of Presentation
      Concorde Hotel, Singapore
    • Year and Date
      2014-08-22 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-26462916
  • 1.  ONOZUKA Minoru (90084780)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 28 results
  • 2.  IINUMA Mitsuo (70184364)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 72 results
  • 3.  CHEN Huayue (20273146)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 89 results
  • 4.  SASAGURI Kin-ichi (10235286)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 5.  FUJIWARA Shu (50229069)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  WATANABE Kazuko (40158621)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 7.  KATO Tomohiro (40224521)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  FUJITA Masafumi (50021449)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  KANEMATSU Masayuki (40252134)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  Takahashi Toru (80324292)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 11.  Yamamoto Toshiharu (50111901)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 12.  KARASAWA Nobuyuki (70148287)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 13.  安細 敏弘 (80244789)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  徳永 美希 (90610238)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 15.  WATANABE Kazuko (50140413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KIMU Wanze (50434395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  KOGAYA Yasutoku (30076046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  DOI Yutaka (40116067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TOMIDA Mihoko (00366329)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ICHIHASHI Yukiko (70515634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 21.  TAMURA Yasuo (40113047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 22.  NISHIYAMA Katsuhiro (20084783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  平野 好幸 (50386843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  安川 然太 (60443454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  山本 裕子 (60756568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  長岡 花恵 (80882943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  山田 久美子 (70737189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  梶本 京子 (30880744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  越智 鈴子 (70912591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  園田 茂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  水谷 謙明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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