Takagi Hirotaka 高木弘隆

… Alternative Names

高木弘隆タカギヒロタカ

TAKAGI Hirotaka 高木弘隆

Less

Researcher Number	00332362
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所安全管理研究センター, 室長
Affiliation (based on the past Project Information) *help	2024: 国立感染症研究所, 安全実験管理部, 室長 2020 – 2022: 国立感染症研究所, 安全実験管理部, 主任研究官 2016 – 2017: 国立感染症研究所, バイオセーフティ管理室, 研究員 2015: 国立感染症研究所, その他部局等, 研究員 2003 – 2006: 国立感染症研究所, バイオセーフティ管理室, 研究官
Review Section/Research Field	Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 53010:Gastroenterology-related / Veterinary medical science / Hygiene
Keywords	Except Principal Investigator サポウイルス / 胆汁酸 / リバースジェネティクス / ウイルス継代 / ウイルス増殖系 / 十二指腸由来細胞 / ウイルスリソース / ヒト十二指腸細胞 / ウイルス大量調製 / ウイルス受容体候補因子 … More / 抗原多様性 / ヒト十二指腸細胞株 / パレコウイルス / ウイルス感受性規定因子 / 特異抗血清 / virion / ウイルスストック / HuTu80 / ヒト十二指腸由来細胞株 / マウスノロウイルス / ネコカリシウイルス / ブタサポウイルス / 感受性細胞 / ノロウイルス / カリシウイルス / Biological terrorism / Pathogen / Infectious aerosol / Crisis-management / Microorganism / Infectious disease / Protective clothing / Biohazard / バイオテロ / 病原体 / 感染性エアロゾル / 危機管理 / 微生物 / 感染症 / 防護服 / バイオハザード Less

集団感染を引き起こしやすいヒト下痢症ウイルスの感染制御法開発のための研究
- Principal Investigator
  
  岡智一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  National Institute of Infectious Diseases
Research to secure resources for sapoviruses and to elucidate the mechanism of growth of gastrointestinal infections
- Principal Investigator
  
  OKA Tomoichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Institute of Infectious Diseases
Trials to improve and establish animal and human noroviruses and sapoviruses in cultured cells
- Principal Investigator
  
  Oka Tomoichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  National Institute of Infectious Diseases
Performance and usage standard of protective clothing against biohazard measures
- Principal Investigator
  
  SHINOHARA Katsuaki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  National Institute of Infectious Diseases

All 2023 2022 2021 2020 2017 2016

All Journal Article Presentation

[Journal Article] Myeloid-associated differentiation marker is an essential host factor for human parechovirus PeV-A3 entry2023
- Author(s)
  Watanabe Kanako、Oka Tomoichiro、Takagi Hirotaka、Anisimov Sergei、Yamashita Shun-ichi、Katsuragi Yoshinori、Takahashi Masahiko、Higuchi Masaya、Kanki Tomotake、Saitoh Akihiko、Fujii Masahiro
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1817-1817
- DOI
  10.1038/s41467-023-37399-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15377, KAKENHI-PROJECT-21KK0166, KAKENHI-PROJECT-20K07757, KAKENHI-PROJECT-20K08320, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23878, KAKENHI-PROJECT-19K08294
[Journal Article] Characterization of a Human Sapovirus Genotype GII.3 Strain Generated by a Reverse Genetics System: VP2 Is a Minor Structural Protein of the Virion.2022
- Author(s)
  Li T-C, Kataoka M, Doan YH, Saito H, Takagi H, Muramatsu M, Oka T.
- Journal Title
  
  Viruses.
  
  Volume: 14 (8) Issue: 8 Pages: 1649-1649
- DOI
  10.3390/v14081649
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08320
[Journal Article] A Human Intestinal Cell Line Suitable for the Propagation of Human Parechovirus Type 1 to 6 with a Clear Cytopathic Effect2022
- Author(s)
  Takagi T, Oka T, Ami Y, Suzaki Y, Saito H.
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 75 Issue: 3 Pages: 318-321
- DOI
  10.7883/yoken.JJID.2021.534
- NAID
  130008094754
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2022-05-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08320
[Journal Article] 汎用培養細胞によるヒトサポウイルスの培養法について2021
- Author(s)
  高木弘隆, 岡智一郎.
- Journal Title
  
  食品衛生学雑誌
  
  Volume: 62
- NAID
  40022639420
- Data Source
  KAKENHI-PROJECT-20K08320
[Journal Article] A human intestinal cell line suitable for the propagation of Type 1-6 human parechovirus with a clear cytopathic effect.2021
- Author(s)
  2.Takagi T, Oka T, Ami Y, Suzaki Y, Saito H.
- Journal Title
  
  Jpn J Infect Dis.
  
  Volume: -
- NAID
  130008094754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08320
[Journal Article] Polymerase chain reaction primer sets for the detection of genetically diverse human sapoviruses2020
- Author(s)
  Oka Tomoichiro、Yamamoto Seiji P.、Iritani Nobuhiro、Sato Shigenori、Tatsumi Chika、Mita Tetsuo、Yahiro Shunsuke、Shibata Shinichiro、Wu Fang-Tzy、Takagi Hirotaka
- Journal Title
  
  Archives of Virology
  
  Volume: 165 Issue: 10 Pages: 2335-2340
- DOI
  10.1007/s00705-020-04746-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08320
[Journal Article] Human sapovirus propagation in human cell lines supplemented with bile acids2020
- Author(s)
  Takagi Hirotaka、Oka Tomoichiro、Shimoike Takashi、Saito Hiroyuki、Kobayashi Takayuki、Takahashi Tomoko、Tatsumi Chika、Kataoka Michiyo、Wang Qiuhong、Saif Linda J.、Noda Mamoru
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 50 Pages: 32078-32085
- DOI
  10.1073/pnas.2007310117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08320
[Journal Article] A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions2017
- Author(s)
  Yokoyama Masaru、Oka Tomoichiro、Takagi Hirotaka、Kojima Hirotatsu、Okabe Takayoshi、Nagano Tetsuo、Tohya Yukinobu、Sato Hironori
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 8 Pages: 1383-1383
- DOI
  10.3389/fmicb.2017.01383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08824, KAKENHI-PROJECT-15K07734
[Journal Article] Antiviral effect of theaflavins against caliciviruses2017
- Author(s)
  Ohba, M., Oka, T., Ando, T., Arahata, S., Ikegaya, A., Takagi, H., Ogo, N., Zhu, C., Owada, K., Kawamori, F., Wang, Q., Saif, L. J. and Asai, A.
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 70 Issue: 4 Pages: 443-447
- DOI
  10.1038/ja.2016.128
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07734
[Journal Article] Discovery and Synthesis of Heterocyclic Carboxamide Derivatives as Potent Anti-norovirus Agents2016
- Author(s)
  Mai Ohba, Tomoichiro Oka, Takayuki Ando, Saori Arahata, Asaka Ikegaya, Hirotaka Takagi, Naohisa Ogo, Kazuhiro Owada, Fumihiko Kawamori, Qiuhong Wang, Linda J. Saif, Akira Asai
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 5 Pages: 465-475
- DOI
  10.1248/cpb.c16-00001
- NAID
  130005148748
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07734
[Presentation] 汎用細胞増殖系を活用した下痢症ウイルスの浄水処理性の評価,2022
- Author(s)
  白崎伸隆, 胡秋晗, 白川大樹, 高木弘隆, 岡智一郎, 松下拓, 松井佳彦
- Organizer
  ウイルス性下痢症研究会第33回学術集会
- Data Source
  KAKENHI-PROJECT-20K08320
[Presentation] 非胃腸炎症例の咽頭拭い液からの下痢症ウイルス検出2022
- Author(s)
  岡智一郎、高木弘隆、斎藤博之
- Organizer
  第63回日本臨床ウイルス学会
- Data Source
  KAKENHI-PROJECT-20K08320
[Presentation] ヒトサポウイルス研究加速のための遺伝子型網羅的リソース確立に向けた取り組み2022
- Author(s)
  岡智一郎、李天成、米満研三、網康至、須崎百合子、中村（桶本）優子、片岡紀代、団海燕、三田哲朗、小林孝行、斎藤博之、八尋俊輔、佐藤重紀、柴田伸一郎、塚田竜介、高木弘隆
- Organizer
  第69回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-20K08320
[Presentation] ヒトパレコウイルスの受容体遺伝子の同定.2021
- Author(s)
  2.渡邉香奈子,岡智一郎,高木弘隆,Anisimov Sergei,高橋雅彦,大桑孝子,樋口雅也,藤井雅寛.
- Organizer
  日本ウイルス学会　第68回学術集会
- Data Source
  KAKENHI-PROJECT-20K08320
[Presentation] 腸管系ウイルス培養における新知見-ヒトの生理からウイルス増殖を考える-2021
- Author(s)
  高木弘隆, 岡智一郎.
- Organizer
  ウイルス性下痢症研究会　第32回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08320
[Presentation] Discovery of novel anti-calicivirus agents.2016
- Author(s)
  Ohba, M., Oka, T., Ando, T., Arahata, S., Ikegaya, A., Takagi, H., Ogo, N., Zhu, C., Owada, K., Kawamori, F., Wang, Q., Saif, L. J. and Asai, A.
- Organizer
  The 3rd International Conference on Pharma-Food (ICPF 2016)
- Place of Presentation
  静岡
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07734
[Presentation] Discovery and synthesis of heterocyclic carboxamide derivatives as potent anti-norovirus agents.2016
- Author(s)
  Ohba, M., Oka, T., Ando, T., Arahata, S., Ikegaya, A., Takagi, H., Ogo, N., Zhu, C., Owada, K., Kawamori, F., Wang, Q., Saif, L. J. and Asai, A.
- Organizer
  The 6th International Calicivirus Conference
- Place of Presentation
  Savannah, GA, USA.
- Year and Date
  2016-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07734
[Presentation] 抗ノロウイルス活性を有する低分子化合物の探索2016
- Author(s)
  大場舞, 岡智一郎, 安藤隆幸, 荒畑沙織, 池ヶ谷朝香, 高木弘隆, 小郷尚久, 小和田和宏, 川森文彦, 浅井章良
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  神奈川県横浜市みなとみらい (パシフィコ横浜)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K07734
[Presentation] 培養可能なカリシウイルスの新規plasmid-basedリバースジェネティクス系の構築2016
- Author(s)
  岡　智一郎、高木弘隆、遠矢幸伸
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K07734
[Presentation] ネコカリシウイルスプロテアーゼの基質特徴を有する非ペプチド性低分子化合物の抗ウイルス活性2016
- Author(s)
  岡　智一郎、高木弘隆、横山勝、小島宏建、岡部隆義、長野哲雄、佐藤裕徳
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  神奈川県横浜市みなとみらい (パシフィコ横浜)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K07734

1. Oka Tomoichiro (50356242)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. SHINOHARA Katsuaki (60117356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SUGIYAMA Kazuyoshi (90150185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YOSHIDA Hiromu (30270656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANAOKA Chikao (00019770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MYOJO Toshihiko (00209959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 渡辺道彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. アニシモフセルゲイ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 横山勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takagi Hirotaka 高木 弘隆

高木 弘隆 タカギ ヒロタカ

TAKAGI Hirotaka 高木 弘隆

Research Projects

Research Products

Co-Researchers

集団感染を引き起こしやすいヒト下痢症ウイルスの感染制御法開発のための研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research to secure resources for sapoviruses and to elucidate the mechanism of growth of gastrointestinal infections

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Trials to improve and establish animal and human noroviruses and sapoviruses in cultured cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Performance and usage standard of protective clothing against biohazard measures

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Myeloid-associated differentiation marker is an essential host factor for human parechovirus PeV-A3 entry2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of a Human Sapovirus Genotype GII.3 Strain Generated by a Reverse Genetics System: VP2 Is a Minor Structural Protein of the Virion.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Human Intestinal Cell Line Suitable for the Propagation of Human Parechovirus Type 1 to 6 with a Clear Cytopathic Effect2022

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] 汎用培養細胞によるヒトサポウイルスの培養法について2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A human intestinal cell line suitable for the propagation of Type 1-6 human parechovirus with a clear cytopathic effect.2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Polymerase chain reaction primer sets for the detection of genetically diverse human sapoviruses2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human sapovirus propagation in human cell lines supplemented with bile acids2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiviral effect of theaflavins against caliciviruses2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discovery and Synthesis of Heterocyclic Carboxamide Derivatives as Potent Anti-norovirus Agents2016

Takagi Hirotaka 高木弘隆

高木弘隆タカギヒロタカ

TAKAGI Hirotaka 高木弘隆