Fujimoto Shimpei 藤本新平

… Alternative Names

FUJIMOTO Shimpei 藤本新平

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Researcher Number	00333576
Other IDs
Affiliation (Current)	2025: 高知大学, 教育研究部医療学系臨床医学部門, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 高知大学, 教育研究部医療学系臨床医学部門, 教授 2015 – 2016: 高知大学, 教育研究部医療学系臨床医学部門, 教授 2011 – 2014: 高知大学, 教育研究部医療学系, 教授 2001 – 2004: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Metabolomics Except Principal Investigator Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator インスリン抵抗性 / 糖尿病 / TBP-2 / インスリン分泌 / 2型糖尿病 / ２型糖尿病 / インスリン感受性 / 分岐鎖アミノ酸 / グルコース輸送 / 代謝障害 … More / ATP産生 / グルコース再吸収 / 糖尿病性腎症 / ミトコンドリア / 代謝障害センサー / ナトリウム・グルコース共役輸送体 / 近位尿細管 / 腎障害 / intracelluar ATP concentration / intracellular Ca^<2+> concentration / exocytotic system / priming effect / glucose / insulin secretion / pancreatic β cell / pancreatic islet / ブドウ島 / 細胞内ATP濃度 / 細胞内Ca^<2+>濃度 / 開口放出機構 / プライミング効果 / ブドウ糖 / 膵β細胞 / 膵ランゲルハンス氏島 / TBP-2 (TXNIP) / インスリン分泌障害 / TBP2(TXNIP) / 耐糖能障害 / グルココルチコイド / TBP-２ / 膵B細胞 / B細胞 / 活性酸素種(ROS) / ATP / 活性酸素種(Ros) / Na-K ATPase … More Except Principal Investigator 人工臓器 / 人工膵臓 / 糖代謝動態 / サルコペニア / 血糖管理 Less

２型糖尿病における分岐鎖アミノ酸異化経路のインスリン感受性低下における役割の解明Principal Investigator
- Principal Investigator
  
  藤本新平
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kochi University
Analysis of glycemic metabolism and exploration of novel therapy for surgical patients with sarcopenia using an artificial pancreas
- Principal Investigator
  
  花崎和弘
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kochi University
Elucidation of roles of metabolic disorder in proximal tubules and its sensor in progression of diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  Fujimoto Shimpei
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kochi University
Is perioperative glycemic control using artificial pancreas possible to prevent glucose toxicity associated with surgical diabetes ?
- Principal Investigator
  
  Hanazaki Kazuhiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kochi University
Role of TBP-2 in glucocorticoid-induced glucose intolerancePrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Shimpei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kochi University
Role of TBP-2 of pancreatic B cells in glucose intolerancePrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Shimpei
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kochi University
Na-K ATPase抑制、活性酸素種産生を介するインスリン分泌障害機構の解析Principal Investigator
- Principal Investigator
  
  藤本新平
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
The mechanism of glucose-induced time-dependent potentiation of insulin secretion from pancreatic β cells and its alteration in diabetic statePrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Shimpei
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  KYOTO UNIVERSITY

All 2023 2022 2021 2020 2019 2018 2014 2013 2012 2011 2010 2005 Other

All Journal Article Presentation

[Journal Article] What is the optimal range of glycemic control for non‐diabetic patients undergoing gastroenterological surgery? A single‐center randomized controlled trial using an artificial pancreas2023
- Author(s)
  Tanioka Nobuhisa、Maeda Hiromichi、Uemura Sunao、Munekage Masaya、Kitagawa Hiroyuki、Namikawa Tsutomu、Kuroiwa Hajime、Fujimoto Shimpei、Seo Satoru、Hanazaki Kazuhiro
- Journal Title
  
  Artificial Organs
  
  Volume: 47 Issue: 6 Pages: 943-950
- DOI
  10.1111/aor.14547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K12647
[Journal Article] Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer2021
- Author(s)
  Sugase Takahito、Takahashi Tsuyoshi、Serada Satoshi、Fujimoto Minoru、Ohkawara Tomoharu、Hiramatsu Kosuke、Koh Masahiro、Saito Yurina、Tanaka Koji、Miyazaki Yasuhiro、Makino Tomoki、Kurokawa Yukinori、Yamasaki Makoto、Nakajima Kiyokazu、Hanazaki Kazuhiro、Mori Masaki、Doki Yuichiro、Naka Tetsuji
- Journal Title
  
  Oncotarget
  
  Volume: 12 Issue: 21 Pages: 2232-2233
- DOI
  10.18632/oncotarget.28096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K12064, KAKENHI-PROJECT-21K12647
[Journal Article] Anti-Glypican-1 Antibody-drug Conjugate as Potential Therapy Against Tumor Cells and Tumor Vasculature for Glypican-1-Positive Cholangiocarcinoma2021
- Author(s)
  Yokota Keiichiro、Serada Satoshi、Tsujii Shigehiro、Toya Keisuke、Takahashi Tsuyoshi、Matsunaga Takashi、Fujimoto Minoru、Uemura Sunao、Namikawa Tsutomu、Murakami Ichiro、Kobayashi Shogo、Eguchi Hidetoshi、Doki Yuichiro、Hanazaki Kazuhiro、Naka Tetsuji
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 20 Issue: 9 Pages: 1713-1722
- DOI
  10.1158/1535-7163.mct-21-0015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K12064, KAKENHI-PROJECT-21K12647, KAKENHI-PROJECT-20K16960
[Journal Article] A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma2021
- Author(s)
  Munekage Eri、Serada Satoshi、Tsujii Shigehiro、Yokota Keiichiro、Kiuchi Keita、Tominaga Kenji、Fujimoto Minoru、Kanda Mizuki、Uemura Sunao、Namikawa Tsutomu、Nomura Taisei、Murakami Ichiro、Hanazaki Kazuhiro、Naka Tetsuji
- Journal Title
  
  Neoplasia
  
  Volume: 23 Issue: 9 Pages: 939-950
- DOI
  10.1016/j.neo.2021.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12064, KAKENHI-PROJECT-21K12647, KAKENHI-PROJECT-20K16960, KAKENHI-PROJECT-17H01623
[Journal Article] Glypican-1 Is a Novel Target for Stroma and Tumor Cell Dual-Targeting Antibody-Drug Conjugates in Pancreatic Cancer2021
- Author(s)
  Tsujii Shigehiro、Serada Satoshi、Fujimoto Minoru、Uemura Sunao、Namikawa Tsutomu、Nomura Taisei、Murakami Ichiro、Hanazaki Kazuhiro、Naka Tetsuji
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 20 Issue: 12 Pages: 2495-2505
- DOI
  10.1158/1535-7163.mct-21-0335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K12064, KAKENHI-PROJECT-21K12647, KAKENHI-PROJECT-17H01623
[Journal Article] Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes2020
- Author(s)
  Funakoshi S, Yoshimura K, Hirano S, Ohmi S, Amano E, Fukuda Y, Terada Y, Fujimoto S
- Journal Title
  
  Diabetol Metab Syndr
  
  Volume: 12 Issue: 1
- DOI
  10.1186/s13098-020-00579-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11129, KAKENHI-PROJECT-20K19677
[Journal Article] Novel mechanism of impaired metabolism-secretion coupling in β-cells: Loss of cytosolic adenosine triphosphate by leakage (Commentary)2019
- Author(s)
  Fujimoto S
- Journal Title
  
  J Diabetes Investig
  
  Volume: 10 Issue: 6 Pages: 1401-1404
- DOI
  10.1111/jdi.13094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11129
[Journal Article] Knockout of the interleukin-36 receptor protects against renal ischemia-reperfusion injury by reduction of proinflammatory cytokines2018
- Author(s)
  Nishikawa H, Taniguchi Y, Matsumoto T, Arima N, Masaki M, Shimamura Y, Inoue K, Horino T, Fujimoto S, Ohko K, Komatsu T, Udaka K, Sano S, Terada Y.
- Journal Title
  
  Kidney Int.
  
  Volume: 93 Issue: 3 Pages: 599-614
- DOI
  10.1016/j.kint.2017.09.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19491, KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-16K14611, KAKENHI-PROJECT-18K08212, KAKENHI-PROJECT-18K11129
[Journal Article] Fasting plasma mannose levels are associated with insulin sensitivity independent of BMI in Japanese individuals with diabetes.2018
- Author(s)
  Amano E, Funakoshi S, Yoshimura K, Hirano S, Ohmi S, Takata H, Terada Y, Fujimoto S
- Journal Title
  
  Diabetol Metab Syndr
  
  Volume: 10 Issue: 1
- DOI
  10.1186/s13098-018-0391-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11129
[Journal Article] Palmitate induces reactive oxygen species production andβ-cell dysfunction by activating NADPH oxidase via Src signaling2014
- Author(s)
  Sato Y, Fujimoto S, Mukai E, Sato H, Tahara Y, Ogura K, Yamano G, Ogura M, Nagashima K, Inagaki N
- Journal Title
  
  J Diabetes Investig
  
  Volume: 5 Issue: 1 Pages: 19-26
- DOI
  10.1111/jdi.12124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-25461330, KAKENHI-PROJECT-25461346
[Journal Article] 酸化ストレスと膵β細胞機能2013
- Author(s)
  田原裕美子、藤本新平、稲垣暢也
- Journal Title
  
  Diabetes Frontier
  
  Volume: 24 Pages: 527-232
- URL
  http://www.m-review.co.jp/
- Data Source
  KAKENHI-PROJECT-23591308
[Journal Article] Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury2013
- Author(s)
  Ishihara M, Urushido M, Hamada K, Matsumoto T, Shimamura Y, Ogata K, Inoue K, Taniguchi Y, Horino T, Fujieda M, Terada Y
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 305(4) Issue: 4 Pages: 495-509
- DOI
  10.1152/ajprenal.00642.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390227, KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-23591573, KAKENHI-PROJECT-23790946, KAKENHI-PROJECT-25670412, KAKENHI-PROJECT-25860683
[Journal Article] Tetrahydro biopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase- dependent manner in diabetic mice2013
- Author(s)
  Abudukadier A, Fujita Y, Obara A, Ohashi A, Fukushima T, Sato Y, Ogura M, Nakamura Y, Fujimoto S, Hosokawa M, Hasegawa H, Inagaki N
- Journal Title
  
  Diabetes
  
  Volume: 62 Issue: 9 Pages: 3033-3043
- DOI
  10.2337/db12-1242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-25293210
[Journal Article] Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction2013
- Author(s)
  Sasaki M, Fujimoto S, Sato Y, Nishi Y, Mukai E, Yamano G, Sato H, Tahara Y, Ogura K, Nagashima K, Inagaki N
- Journal Title
  
  Diabetes
  
  Volume: 62 Issue: 6 Pages: 1996-2003
- DOI
  10.2337/db12-0903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590977, KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-25293210, KAKENHI-PROJECT-25461330, KAKENHI-PROJECT-25461346, KAKENHI-PROJECT-25670258
[Journal Article] Upregulation of HNF-1β during experimental acute kidney injury plays a crucial role in renal tubule regeneration.2012
- Author(s)
  Ogata K,Inoue K,et al
- Journal Title
  
  10.1152/ajprenal.00086
  
  Volume: 303 Issue: 5 Pages: 689-699
- DOI
  10.1152/ajprenal.00086.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790816, KAKENHI-PROJECT-22790793, KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-23790946
[Journal Article] Liver X receptorαis involved in the transcriptional regulation of the 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase gene2012
- Author(s)
  Zhao LF, Iwasaki Y, Nishiyama M, Taguchi T, Tsugita M, Okazaki M, Nakayama S, Kambayashi M, Fujimoto S, Hashimoto K, Murao K, Terada Y
- Journal Title
  
  Diabetes
  
  Volume: 61 Issue: 5 Pages: 1062-1071
- DOI
  10.2337/db11-1255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-24591352
[Journal Article] Molecular mechanism of impaired metabolism-secretion coupling in diabetic pancreaticβcells2011
- Author(s)
  Fujimoto S
- Journal Title
  
  Diabetol Int
  
  Volume: 2 Issue: 3 Pages: 122-126
- DOI
  10.1007/s13340-011-0040-0
- Data Source
  KAKENHI-PROJECT-23591308
[Journal Article] 2型糖尿病のインスリン分泌障害において膵β細胞の機能低下あるいはmassの減少のどちらが重要なのか?2011
- Author(s)
  藤本新平、稲垣暢也
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 32 Pages: 399-401
- NAID
  40018869236
- URL
  http://www.kahyo.com/
- Data Source
  KAKENHI-PROJECT-23591308
[Journal Article] Role of endogenous ROS production in impaired metabolism-secretion coupling of diabetic pancreaticβcells2011
- Author(s)
  Fujimoto S, Mukai E, Inagaki N
- Journal Title
  
  Prog Biophys Mol Biol
  
  Volume: 107 Issue: 2 Pages: 304-310
- DOI
  10.1016/j.pbiomolbio.2011.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-23791028
[Journal Article] Ionic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic βcells: a simulation study2011
- Author(s)
  Cha CY , Nakamura Y, Himeno Y, Wang J,Fujimoto S, Inagaki N, Earm YE, Noma A
- Journal Title
  
  J Gen Physiol
  
  Volume: 138(1)巻 Issue: 1 Pages: 21-37
- DOI
  10.1085/jgp.201110611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390039, KAKENHI-PROJECT-22590216, KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-23791026
[Journal Article] Role of mitochondrial phosphate carrier in metabolism-secretion coupling in rat insulinoma cell line INS-12011
- Author(s)
  Nishi Y, Fujimoto S, Sasaki M, Mukai E, Sato H, Sato Y, Tahara Y, Nakamura Y, Inagaki N
- Journal Title
  
  Biochem J
  
  Volume: 435 Issue: 2 Pages: 421-430
- DOI
  10.1042/bj20101708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-23791026, KAKENHI-PROJECT-23791028
[Journal Article] Systems Analysis of GLP-1 Receptor Signaling in Pancreatic {beta}-cells2011
- Author(s)
  Takeda Y, Amano A, Noma A, Nakamura Y, Fujimoto S, Inagaki N
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 301(4) Issue: 4 Pages: C792-C803
- DOI
  10.1152/ajpcell.00057.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136004, KAKENHI-PROJECT-22390039, KAKENHI-PROJECT-23591308, KAKENHI-PROJECT-23791026
[Journal Article] Targetingβ-cell functions in therapy for type 2d iabetes2011
- Author(s)
  Fujimoto S, Inagaki N
- Journal Title
  
  J Diabetes Investig
  
  Volume: 2 Issue: 3 Pages: 178-179
- DOI
  10.1111/j.2040-1124.2011.00117.x
- Data Source
  KAKENHI-PROJECT-23591308
[Journal Article] Exendin-4 suppresses SRC activity and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner2010
- Author(s)
  Mukai E, Fujimoto S, Sato H, Oneyama C, Kominato R, Sato Y, Sasaki M, Nishi Y, Okada M, Inagaki N
- Journal Title
  
  Diabetes
  
  Volume: 60(1) Issue: 1 Pages: 218-226
- DOI
  10.2337/db10-0021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689009, KAKENHI-PROJECT-23591308
[Journal Article] Tacrolimus suppresses glucose-induced insulin release from pancreatic islets by reducing glucokinase activity.2005
- Author(s)
  Radu RG, Fujimoto S et al.
- Journal Title
  
  American Journal of Physiology Endocrinology and Metabolism 288(2)
- Data Source
  KAKENHI-PROJECT-15790464
[Journal Article] Chronic exposure to β-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents2005
- Author(s)
  Takehiro M, Fujimoto S et al.
- Journal Title
  
  American Journal of Physiology Endocrinology and Metabolism 288(2)
- Data Source
  KAKENHI-PROJECT-15790464
[Journal Article] グルコースによるインスリン分泌動態惹起経路と増幅経路
- Author(s)
  藤本新平
- Journal Title
  
  日本臨床
  
  Volume: 70増刊(最新臨床糖尿病学) Pages: 104-108
- URL
  http://www.nippon-rinsho.co.jp/
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] 様々な耐糖能の程度の日本人における血中チロシンとインスリン感受性との相関分析2022
- Author(s)
  天野絵梨，吉村久美子，船越生吾，平野世紀，近江訓子，江口智浩，門脇祐治，寺田典生，藤本新平
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K11574
[Presentation] Correlation analysis between insulin sensitivity, branched-chain acid, and adiponectin levels in Japanese individuals with varying degrees of glucose tolerance2020
- Author(s)
  Amano E, Yoshimura K, Funakoshi S, Hirano S, Ohmi S, Terada Y, Fujimoto S
- Organizer
  American Diabetes Association, 80th Scientific Sessions, Chicago (On line sessions), IL, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11129
[Presentation] Undercarboxylated osteocalcin is correlated with insulin secretion in Japanese individuals with diabetes2019
- Author(s)
  Funakoshi S, Ohmi S, Amano E, Terada Y, Fujimoto S
- Organizer
  American Diabetes Association, 79th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11129
[Presentation] リンゴ由来プロシアニジン類による糖尿病モデルマウスにおける抗糖尿病作用の検討2013
- Author(s)
  小倉かさね、藤本新平、稲垣暢也(他9名)
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本他、熊本市
- Year and Date
  2013-05-18
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Palmitate induces ROS production and β-cell dysfunction by activating NADPH oxidase via Src signaling2013
- Author(s)
  Sato Y, Fujimoto S, Mukai E, Sato H, Tahara Y, Ogura K, Yamano G, Ogura M, Nagashima K, Seino Y, Inagaki N
- Organizer
  American Diabetes Association, 73rd Scientific Sessions
- Place of Presentation
  McCormick Place, Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Srcはグルコキナーゼ活性調節を介して膵β細胞グルコース応答性インスリン分泌に関与する2013
- Author(s)
  佐藤広規、藤本新平、稲垣暢也(他9名)
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本他、熊本市
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Thioredoxin binding protein-2(TBP- 2)が膵β細胞で果たす役割についての検討2013
- Author(s)
  田原裕美子、藤本新平、稲垣暢也(他9名)
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本他、熊本市
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Palmitate induces ROS production andβ-cell dysfunction by activating NADPH oxidase via Src signaling, American Diabetes Association2013
- Author(s)
  Sato Y, Fujimoto S, Mukai E, Sato H, Tahara Y, Ogura K, Yamano G, Ogura M, Nagashima K, Seino Y, Inagaki N
- Organizer
  73rd Scientific Sessions
- Place of Presentation
  Moscone Center, Chicago, IL, USA
- Year and Date
  2013-06-23
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Persistent reduction of ROS ameliorates metabolism-secretion coupling in cultured diabetic GK Islets by suppressing Warburg effect2012
- Author(s)
  Sasaki M, Fujimoto S, Nishi Y, Mukai E, Yamano G, Sato Y, Sato H, Tahara Y, Ogura K, Nagashima K, Inagaki N
- Organizer
  American Diabetes Association, 72nd Scientific Sessions
- Place of Presentation
  McCormic Place Convention Center, Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Persistent reduction of ROS ameliorates metabolism-secretion coupling in cultured diabetic GK Islets by suppressing Warburg effect2012
- Author(s)
  Sasaki M, Fujimoto S, Nishi Y, Mukai E, Yamano G, Sato Y, Sato H, Tahara Y, Ogura K, Nagashima K, Inagaki N
- Organizer
  American Diabetes Association, 72nd Scientific Sessions
- Place of Presentation
  McCormick Place Convention Center, Philadelphia, PA, USA
- Year and Date
  2012-06-10
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] 活性酸素種抑制によるWarburg効果改善を介するGKラットインスリン分泌障害改善効果癌代謝類似代謝障害制御の重要性2012
- Author(s)
  佐々木真弓、藤本新平、稲垣暢也(他8名)
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] 糖尿病における膵β細胞代謝-分泌連関障害の分子機構2011
- Author(s)
  藤本新平
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  さっぽろ芸術文化の館、札幌市(受賞講演1(リリー賞))
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Impaired insulin secretion due to mitochondrial dysfunction in diabetes2011
- Author(s)
  Fujimoto S
- Organizer
  Croucher Foundation Advance Study Institute (ASI) on"Mitochondrial Stress in Diabetes and Aging"
- Place of Presentation
  Mrs Chen Yang Foo Oi Telemedicine Centre, Hong Kong, China
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Metabolic dysfunction in diabetes : Metabolic pathways at the crossroads of diabetes and cancer2011
- Author(s)
  Fujimoto S
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  ヒルトン東京ベイ,Tokyo, Japan
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Role of endogenous ROS production in metabolism-secretion coupling of pancreaticβ-cells2011
- Author(s)
  Fujimoto S, Mukai E, Inagaki N
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌、札幌市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Impaired insulin secretion due to mitochondrial dysfunction in diabetes2011
- Author(s)
  Fujimoto S
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  ヒルトン東京ベイ,Tokyo, Japan
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Role of endogenous ROS production in amelioration of impaired metabolism-secretion coupling of diabetesβ-cells by augmentation of GLP-1 signals2011
- Author(s)
  Fujimoto S, Mukai E, Inagaki N
- Organizer
  Asia Islet Biology & Incretin Symposium (AIBIS) 2011
- Place of Presentation
  Crowne Plaza, Beijing, China
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] シンポジウム(英語)：Role of endogenous ROS production in metabolism-secretion coupling of pancreatic β-cells
- Author(s)
  Fujimoto S, Mukai E, Inagaki N
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] 平成23年度糖尿病学会賞（リリー賞）受賞講演：糖尿病における膵β細胞代謝-分泌連関障害の分子機構
- Author(s)
  藤本新平
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  さっぽろ芸術文化の館（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Metabolic dysfunction in diabetes: Metabolic pathways at the crossroads of diabetes and cancer
- Author(s)
  Fujimoto S
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  ヒルトン東京ベイ（千葉県浦安市）
- Data Source
  KAKENHI-PROJECT-23591308
[Presentation] Impaired insulin secretion due to mitochondrial dysfunction in diabetes
- Author(s)
  Fujimoto S
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  ヒルトン東京ベイ（千葉県浦安市）
- Data Source
  KAKENHI-PROJECT-23591308

1. INAGAKI Nobuya (30241954)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. Hanazaki Kazuhiro (30240790)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 北川博之 (10403883)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 並川努 (50363289)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 上村直 (80566191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. NAGASHIMA Kazuaki (40324628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 藤澤和音 (20767991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 矢田部智昭 (60437720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 前田広道 (20437734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 宮村充彦 (70464378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 谷岡信寿 (80898099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 宗景匡哉 (90554478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. INOUE Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. HORINO Taro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. CHA Chae young

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小根山千歳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 寺田典生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 野間昭典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 天野晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 島村芳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujimoto Shimpei 藤本 新平

FUJIMOTO Shimpei 藤本 新平

Research Projects

Research Products

Co-Researchers

２型糖尿病における分岐鎖アミノ酸異化経路のインスリン感受性低下における役割の解明Principal Investigator

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Analysis of glycemic metabolism and exploration of novel therapy for surgical patients with sarcopenia using an artificial pancreas

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Elucidation of roles of metabolic disorder in proximal tubules and its sensor in progression of diabetic nephropathyPrincipal Investigator

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Is perioperative glycemic control using artificial pancreas possible to prevent glucose toxicity associated with surgical diabetes ?

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Role of TBP-2 in glucocorticoid-induced glucose intolerancePrincipal Investigator

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Role of TBP-2 of pancreatic B cells in glucose intolerancePrincipal Investigator

Principal Investigator

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Na-K ATPase抑制、活性酸素種産生を介するインスリン分泌障害機構の解析Principal Investigator

Principal Investigator

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The mechanism of glucose-induced time-dependent potentiation of insulin secretion from pancreatic β cells and its alteration in diabetic statePrincipal Investigator

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[Journal Article] What is the optimal range of glycemic control for non‐diabetic patients undergoing gastroenterological surgery? A single‐center randomized controlled trial using an artificial pancreas2023

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[Journal Article] Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer2021

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[Journal Article] Anti-Glypican-1 Antibody-drug Conjugate as Potential Therapy Against Tumor Cells and Tumor Vasculature for Glypican-1-Positive Cholangiocarcinoma2021

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[Journal Article] A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma2021

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[Journal Article] Glypican-1 Is a Novel Target for Stroma and Tumor Cell Dual-Targeting Antibody-Drug Conjugates in Pancreatic Cancer2021

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[Journal Article] Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes2020

Author(s)

Fujimoto Shimpei 藤本新平

FUJIMOTO Shimpei 藤本新平