TAKEYAMA Sadaaki 竹山禎章

Researcher Number	00333823
Affiliation (based on the past Project Information) *help	2007: Tohoku University, 大学院・歯学研究科, 助教 2005 – 2006: 東北大学, 大学院歯学研究科, 助手 2002 – 2006: 東北大学, 大学院・歯学研究科, 助手
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Functional basic dentistry
Keywords	Principal Investigator ビスホスホネート / 抗炎症作用 / 歯周疾患 / 抗酸化作用 / プロスタグランジンE2 / 破骨細胞 / 骨芽細胞 / PGE2 / NO / TNF-alpha … More Except Principal Investigator … More 骨吸収 / 破骨細胞 / bisphosphonate / osteoclast / osteoblast / 骨形成 / ビスホスホネート / 骨芽細胞 / ラット / 時計遺伝子 / カルシトニン / サーカディアンリズム / alveolar bone / prostaglamdin E2 / bone formation / bone-resorption / periodontitis / COX / NO / プロスタグランジン / 抗炎症作用 / 歯周炎 / プロスタグランジンE_2 / 歯槽骨 / プロスタグランジンE2 / 歯周病 / clock gene / calcitonin / chronophamacology / ameloblast / circadian rhythm / クロックマウス / RT-PCR / 軟骨細胞 / 象牙芽細胞 / アメロゲニン / 時間薬理学 / エナメル芽細胞 / 血清 / 骨代謝 / カルシウム / 液性因子 Less

抗炎症作用を併せ持つビスホスホネートの作用機序についてPrincipal Investigator
- Principal Investigator
  
  竹山禎章
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tohoku University
A bisphosphonate for periodontitis with anti-bone-resorbing and anti-inflammatory activities
- Principal Investigator
  
  SHINODA Hisashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tohoku University
破骨細胞機能のサーカディアンリズム発現機構に関する分子生物学的研究
- Principal Investigator
  
  SHINODA Hisashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tohoku University
骨吸収抑制と抗炎症作用を併せもつビスホスホネートの作用機序の検討と臨床応用Principal Investigator
- Principal Investigator
  
  竹山禎章
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tohoku University
非アミノ系ビスホスホネートの抗炎症作用とCox-2mRNA転写抑制の解析Principal Investigator
- Principal Investigator
  
  竹山禎章
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tohoku University
A study on the generation of circadian rhythm in hard tissue metabolism
- Principal Investigator
  
  SHINODA Hisashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tohoku University

All 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Pharmacological topics of bone metabolism: A novel bisphosphonate for the treatment of periodontitis.2008
- Author(s)
  Shinoda H, Takeyama S, Suzuki K, Murakami S, Yamada S
- Journal Title
  
  Journal of Pharmacological Science (in press)
- NAID
  10024319772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791364
[Journal Article] Effect of activin A on osteoclastogenesis in vitro.2007
- Author(s)
  Takeyama S, Yamamoto K, Hirotani H, Echigo S, Shinoda S
- Journal Title
  
  Dentistry in Japan Vol 43
  
  Pages: 1-4
- NAID
  10021953273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791364
[Journal Article] Diurnal rhythm of osteoclastogenesis activity in rat serum2006
- Author(s)
  Yan D, Shao P, Choi B-J, Takeyama S, Shinoda H.
- Journal Title
  
  Journal of pharmacological sciences (In press)
- Data Source
  KAKENHI-PROJECT-16659507
[Journal Article] Risedronate does not interfere with bone formation coupled with lipopolysaccharide-stimulated bone resorption2006
- Author(s)
  Suzuki K, Takeyama S, Yamada S, Shinoda H
- Journal Title
  
  Dentistry in Japan 42
  
  Pages: 38-42
- NAID
  10019595348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] 歯周疾患治療へのビスホスホネートの応用2006
- Author(s)
  篠田壽, 竹山禎章
- Journal Title
  
  Clinical Calcium 16(2)
  
  Pages: 117-122
- Data Source
  KAKENHI-PROJECT-16791122
[Journal Article] Current topics in pharmacological research on bone metabolism : inhibitory effects of bisphosphonates on the differentiation and activity of osteoclasts.2006
- Author(s)
  Suzuki K, Takeyama S, Sakai Y, Yamada S, Shinoda H
- Journal Title
  
  J Pharmacol. Sci. Vol. 100(3)
  
  Pages: 189-194
- NAID
  10018240255
- Data Source
  KAKENHI-PROJECT-18791364
[Journal Article] Diurnal rhythm in the effect at calcitonin in rats2006
- Author(s)
  Shao P, Takeyama S, Yan D, Isoya M, Shinoda H.
- Journal Title
  
  Journal of pharmacological sciences (In press)
- Data Source
  KAKENHI-PROJECT-16659507
[Journal Article] Risedronate does not interfere with bone formation coupled with lipopolysaccharide-stimulated bone resorption.2006
- Author(s)
  Suzuki K, Takeyama S, Yamada S, Shinoda H
- Journal Title
  
  Dentistry in Japan 42
  
  Pages: 38-42
- NAID
  10019595348
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Application of bisphosphonates for periodontitis2006
- Author(s)
  Shinoda H, Takeyama S
- Journal Title
  
  Clinical Calcium 16(2)
  
  Pages: 117-123
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Effect of activin A on osteoclastogenesis in vitro.2006
- Author(s)
  Takeyama S, Yamamoto K, Hirotani H, Echigo S, Shinoda H
- Journal Title
  
  Dentistry in Japan Vol. 43
  
  Pages: 37-40
- NAID
  10021953273
- Data Source
  KAKENHI-PROJECT-18791364
[Journal Article] Inhibitory effects of bisphosphonates on the differentiation and activity of osteoclasts.2006
- Author(s)
  Suzuki K, Takeyama S, Sakai Y, Yamada S, Shinoda H
- Journal Title
  
  Journal of Pharmacological Science 100巻4号
  
  Pages: 189-194
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Inhibitory effects of bisphosphonates on the differentiation and activity of osteoclasts2006
- Author(s)
  Suzuki K, Takeyama S, Sakai Y, Yamada S, Shinoda H.
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 189-194
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Inhibitory effects of bisphosphonates on the differentiation and activity of osteoclasts2006
- Author(s)
  Suzuki K, Takeyama S, Sakai Y, Yamada S, Shinoda H
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 189-194
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Inhibitory effects of bisphosphonates on the differentiation and activity of osteoclasts.2006
- Author(s)
  Suzuki K, Takeyama S, Sakai Y, Yamada S, Shinoda H
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 189-194
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Risedronate does not interfere with bone resorption coupled with lipopolysaccharide-stimulated bone resorption2006
- Author(s)
  Suzuki K, Takeyama S, Yamada S, Shinoda H
- Journal Title
  
  Dentistry in Japan 42巻2号
  
  Pages: 38-42
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Osteoclast responses to lipopolysaccharide, parathyroid hormone and bisphosphonate in neonatal murine calvaria analyzed by laser scanning confocal microscopy2005
- Author(s)
  Suzuki K, Takeyama S, Kikuchi T, Yamada S, Sodeck J, Shinoda H
- Journal Title
  
  Journal of Histochemistry and Cytochemistry 53
  
  Pages: 1525-1537
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Activin A stimulates osteoclast formation in vtro2005
- Author(s)
  Takeyama S, Yamamoto K, Hirotani H, Echigo S, Shinoda H
- Journal Title
  
  Interface oral health science (Proceeding of the international symposium for interface oral health science, held in Sendai)
  
  Pages: 340-341
- Data Source
  KAKENHI-PROJECT-16791122
[Journal Article] Osteoclast responses to lipopolysaccharide, parathyroid hormone and bisphosphonates in neonatal murine calvaria analyzed by laser scanning confocal microscopy2005
- Author(s)
  Suzuki K, Takeyama S, Kikuchi T, Yamada S, Sodeck J, Shinoda H
- Journal Title
  
  Journal of Histochemistry and Cytochemistry 53
  
  Pages: 1525-1537
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] Osteoclast responses to lipopolysaccharide, parathyroid hormone and bisphosphonates in neonatal murine calvaria analyzed by laser confocal microscopy2005
- Author(s)
  Suzuki K, Takeyama S, Kikuchi K, Yamada S, Sodeck K, Shinoda H.
- Journal Title
  
  Journal of Histochemistry and Cytochemistry 53(12)
  
  Pages: 1525-1537
- Data Source
  KAKENHI-PROJECT-17390491
[Journal Article] ビスホスホネートの歯周疾患治療医学への応用2005
- Author(s)
  竹山禎章, 篠田壽
- Journal Title
  
  日本歯科評論 Vol.65 No.1
  
  Pages: 83-86
- NAID
  10018373112
- Data Source
  KAKENHI-PROJECT-16791122
[Journal Article] Osteoclast responses to lipoplysaccharide, parathyroid hormone and bisphosphonates in neonatal murine calvaria analyzed by laser scanning confocal microscopy.2005
- Author(s)
  Suzuki K, Takeyama S, Kikuchi T, Yamada S, Sodek J, Shinoda H
- Journal Title
  
  Journal of Histochemistry and Cytochemistry 53(12)
  
  Pages: 1525-1537
- Data Source
  KAKENHI-PROJECT-16791122
[Journal Article] Twenty-four-hour rhythm of osteoclastogenic activity in rat serum2005
- Author(s)
  Dong Yan, S.Takeyama, P.Shao, S.Echigo, H.Shinoda
- Journal Title
  
  Journal of biological rhythms in press
- Data Source
  KAKENHI-PROJECT-16659507
[Journal Article] 骨吸収の日内変動に及ぼすリセドロネートの効果2004
- Author(s)
  鍵和田信行, 竹山禎章, 邵萍, 篠田壽, 越後成志
- Journal Title
  
  東北大学歯学雑誌 23巻2号
  
  Pages: 26-33
- Data Source
  KAKENHI-PROJECT-16659507
[Presentation] 歯周病治療薬としてのビスホスホネートの有用性について2007
- Author(s)
  篠田壽、竹山禎章、鈴木恵子、村上忍、山田庄司
- Organizer
  第80回日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-15
- Data Source
  KAKENHI-PROJECT-18791364

1. SHINODA Hisashi (80014025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. HIROTANI Hiroaki (90312595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SHOJI Kanako (90302158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHIMAUCHI Hidetoshi (70187425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 邵萍 (90361104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

TAKEYAMA Sadaaki 竹山 禎章

Research Projects

Research Products

Co-Researchers

抗炎症作用を併せ持つビスホスホネートの作用機序についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A bisphosphonate for periodontitis with anti-bone-resorbing and anti-inflammatory activities

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

破骨細胞機能のサーカディアンリズム発現機構に関する分子生物学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨吸収抑制と抗炎症作用を併せもつビスホスホネートの作用機序の検討と臨床応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

非アミノ系ビスホスホネートの抗炎症作用とCox-2mRNA転写抑制の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on the generation of circadian rhythm in hard tissue metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pharmacological topics of bone metabolism: A novel bisphosphonate for the treatment of periodontitis.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effect of activin A on osteoclastogenesis in vitro.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Diurnal rhythm of osteoclastogenesis activity in rat serum2006

Author(s)

Journal Title

Data Source

[Journal Article] Risedronate does not interfere with bone formation coupled with lipopolysaccharide-stimulated bone resorption2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] 歯周疾患治療へのビスホスホネートの応用2006

Author(s)

Journal Title

Data Source

[Journal Article] Current topics in pharmacological research on bone metabolism : inhibitory effects of bisphosphonates on the differentiation and activity of osteoclasts.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Diurnal rhythm in the effect at calcitonin in rats2006

Author(s)

Journal Title

Data Source

[Journal Article] Risedronate does not interfere with bone formation coupled with lipopolysaccharide-stimulated bone resorption.2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Application of bisphosphonates for periodontitis2006

TAKEYAMA Sadaaki 竹山禎章