Tada Yayoi 多田弥生

… Alternative Names

TADA Yayoi 多田弥生

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Researcher Number	00334409
Other IDs	https://orcid.org/0000-0003-3743-135X
Affiliation (Current)	2026: 帝京大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help	2026: 帝京大学, 医学部, 主任教授 2018 – 2024: 帝京大学, 医学部, 主任教授 2017: 帝京大学, 医学部, 助手 2008 – 2011: The University of Tokyo, 医学部附属病院, 講師 2008: 東京大学, 医学部・附属病院, 助教 2006 – 2007: 東京大学, 医学部附属病院, 助教 2006: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology
Keywords	Principal Investigator 乾癬 / 膿疱性乾癬 / 樹状細胞 / 免疫学 / 線維芽細胞 / TNF-アルファ Except Principal Investigator CXCL11 / CXCL10 / CXCL9 / prolactin … More / CCL27 / leukotriene B_4 / STAT3 / STAT1 / human β-defensin-2 / leptin / AP-1 / IL-17 / CCL20 / プロラクチン / ケラチノサイト / ケミカルメディエーター / 尋常性乾癬 / 活性化 / 抗原提示 / 共刺激分子 / 樹状細胞 / ランゲルハンス細胞 Less

Elucidation of the mechanism of keratinocyte-derived TARC production and its pathogenic role in pustular psoriasisPrincipal Investigator
- Principal Investigator
  
  多田弥生
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Teikyo University
Identification of TARC-producing cells in pustular psoriasis and elucidation of pathogenesisPrincipal Investigator
- Principal Investigator
  
  多田弥生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Teikyo University
Examining the epidermal resident memory T cell of psoriasis model mousePrincipal Investigator
- Principal Investigator
  
  Tada Yayoi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Teikyo University
Ganglioside as a drug for psoriasisPrincipal Investigator
- Principal Investigator
  
  Tada Yayoi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Teikyo University
尿酸結晶のケラチノサイトへの作用Principal Investigator
- Principal Investigator
  
  多田弥生
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  The University of Tokyo
Regulation of Langerhans cell function by fibroblastsPrincipal Investigator
- Principal Investigator
  
  TADA Yayoi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  The University of Tokyo
The roles of chemical mediators in the pathogenesis of psoriasis vulgaris and their therapeutical application
- Principal Investigator
  
  KANDA Naoko
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Teikyo University
TNFアルファによるランゲルハンス細胞の機能修飾Principal Investigator
- Principal Investigator
  
  多田弥生
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  The University of Tokyo
Investigation of Langerhans cell stimulatory molecule and its application in skin disease therapy
- Principal Investigator
  
  TAMAKI Kunihiko
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Dermatology
- Research Institution
  The University of Tokyo

All 2021 2019 2018 2017 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Other

[Journal Article] Fingolimod ameliorates imiquimod-induced psoriasiform dermatitis by sequestrating interleukin-17-producing ?d T cells in secondary lymph nodes2021
- Author(s)
  Okura Iori、Kamata Masahiro、Asano Yoshihide、Mitsui Aya、Shimizu Teruo、Sato Shinichi、Tada Yayoi
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 102 Issue: 2 Pages: 116-125
- DOI
  10.1016/j.jdermsci.2021.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08696
[Journal Article] Apremilast downregulates interleukin-17 production and induces splenic regulatory B cells and regulatory T cells in imiquimod-induced psoriasiform dermatitis2021
- Author(s)
  Uchida Hideaki、Kamata Masahiro、Shimizu Teruo、Egawa Shota、Ito Makoto、Takeshima Ryosuke、Mizukawa Itsumi、Watanabe Ayu、Tada Yayoi
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 104 Issue: 1 Pages: 55-62
- DOI
  10.1016/j.jdermsci.2021.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08758, KAKENHI-PROJECT-20K08696
[Journal Article] Patient preference for biologic treatments of psoriasis in Japan.2019
- Author(s)
  Tada Y, Ishii K, Kimura J, Hanada K, Kawaguchi I.
- Journal Title
  
  J Dermatol.
  
  Volume: 印刷中 Issue: 6 Pages: 466-477
- DOI
  10.1111/1346-8138.14870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10255
[Journal Article] Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL36RN mutation.2019
- Author(s)
  Komatsuda S, Kamata M, Chijiwa C, Namiki K, Fukaya S, Hayashi K, Fukuyasu A, Tanaka T, Ishikawa T, Ohnishi T, Abe K, Yamamoto T, Aozasa N, Sugiura K, Tada Y.
- Journal Title
  
  J Dermatol.
  
  Volume: 46 Issue: 1 Pages: 73-75
- DOI
  10.1111/1346-8138.14711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10255, KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-15H04886
[Journal Article] The vitamin D3 analog, maxacalcitol, reduces psoriasiform skin inflammation by inducing regulatory T cells and downregulating IL-23 and IL-17 production.2018
- Author(s)
  Hau CS, Shimizu T, Tada Y, Kamata M, Takeoka S, Shibata S, Mitsui A, Asano Y, Sugaya M, Kadono T, Sato S, Watanabe S.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 92 Issue: 2 Pages: 117-126
- DOI
  10.1016/j.jdermsci.2018.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10255, KAKENHI-PROJECT-16K10146
[Journal Article] Secukinumab improves psoriasis symptoms in patients with inadequate response to cyclosporine A: A prospective study to evaluate direct switch.2017
- Author(s)
  Ohtsuki M, Morita A, Igarashi A, Imafuku S, Tada Y, Fujita H, Fujishige A, Yamaguchi M, Teshima R, Tani Y, Nakagawa H.
- Journal Title
  
  J Dermatol.
  
  Volume: 44 Issue: 10 Pages: 1105-1111
- DOI
  10.1111/1346-8138.13911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10255
[Journal Article] Vaccination with TAT-antigen fusion protein induces protective, CD8(+) T cell-mediated immunity against Leishmania major.2010
- Author(s)
  Kronenberg K, Brosch S, Butsch F, Tada Y, Shibagaki N, Udey MC, von Stebut E
- Journal Title
  
  J Invest Dermatol. 130
  
  Pages: 2602-10
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Serum TARC/CCI17 levels are increased in dermatomyositis associated with interstitial lung disease.2010
- Author(s)
  Kawashima T, Tada Y, et al.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 160巻 Pages: 52-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Identification of a novel marker for dendritic cell maturation, mouse transmembrane protein 123.2010
- Author(s)
  Takekoshi T, Tada Y, Watanabe T, Sugaya M, Hoashi T, Komine M, Kawashima T, Shimizu T, Hau CS, Asahina A, Yokomizo T, Sato S, Tamaki K
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 31876-84
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Identification of a novel marker for dendritic cell maturation, mouse transmembrane protein 123.2010
- Author(s)
  Takekoshi T, Tada Y, et al.
- Journal Title
  
  journal of biological chemistry
  
  Volume: 285巻 Pages: 31876-31884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Possible roles of IL-27 in the pathogenesis of psoriasis.2010
- Author(s)
  Shibata S, Tada Y, Kanda N, Nashiro K, Kamata M, Karakawa M, Miyagaki T, Kai H, Saeki H, Shirakata Y, Watanabe S, Tamaki K, Sato S
- Journal Title
  
  J Invest Dermatol. 130
  
  Pages: 1034-9
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Prolactin enhances basal and IL-17-induced CCL20 production by human keratinocytes.2009
- Author(s)
  Kanda N, Shibata S, Tada Y, Nashiro K, Tamaki K, Watanabe S
- Journal Title
  
  Eur J Immunol. 39
  
  Pages: 996-1006
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Prolactin enhances basal and IL-17-induced CCL20 production by human keratinocytes.2009
- Author(s)
  Kanda, N., Shibata, S., Tada, Y., Nashiro, K., Tamaki, K., Watanabe, S.
- Journal Title
  
  Eur J Immunol 39
  
  Pages: 996-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591259
[Journal Article] Histamine induces human β-defensin-3 production in human keratinocytes.2009
- Author(s)
  Ishikawa, T., Kanda, N., Hau, C.S., Tada, Y., Watanab e, S.
- Journal Title
  
  J Dermatol Sci 56(2)
  
  Pages: 121-127
- NAID
  10025561175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591259
[Journal Article] Prolactin enhances basal and IL-17-induced CCL20 productionby human keratinocytes.2009
- Author(s)
  Kanda, N., Shibata, S., Tada, Y., Nashiro, K., Tamaki, K., Watanabe, S.
- Journal Title
  
  Eur J Immunol 39
  
  Pages: 996-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591259
[Journal Article] Novel effects of diosgenin on skin aging.2009
- Author(s)
  Tada Y, Kanda N, Haratake A, Tobiishi M, Uchiwa H, Watanabe S
- Journal Title
  
  Steroids 74
  
  Pages: 504-511
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Novel effects of diosgenin on skin aging2009
- Author(s)
  Tada Y, et al.
- Journal Title
  
  Steroids 74
  
  Pages: 504-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Atypical cutaneous sarcoidosis with diffuse, indurated erythema.2009
- Author(s)
  Tada Y, Kanda N, Ohnishi T, Watanabe S
- Journal Title
  
  Eur J Dermatol. 19
  
  Pages: 639-639
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Atypical cutaneous sarcoidosis with diffuse, indurated erythema2009
- Author(s)
  Tada Y, et al.
- Journal Title
  
  European Journal of Dermatology 19
  
  Pages: 639-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Histamine induces human β-defensin-3 production in human keratinocytes.2009
- Author(s)
  Ishikawa, T., Kanda, N., Hau, C.S., Tada, Y., Watanabe, S.
- Journal Title
  
  J Dermatol Sci 56(2)
  
  Pages: 121-127
- NAID
  10025561175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591259
[Journal Article] Serunm levels of souluble CD26 in patients with scleroderma.2008
- Author(s)
  Tamaki Z, Tada Y et al.
- Journal Title
  
  J Dermatol Sci 52
  
  Pages: 67-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Generalized morphea positive for anticentromere antibody.2008
- Author(s)
  Ohmatsu H, Tada Y et al.
- Journal Title
  
  Eur J Dermatol 18
  
  Pages: 718-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Serum 5-S-cysteinyldopa levels in patients with psoriasis undergoing narrowband ultaviolet B phototherapy2008
- Author(s)
  Kikuchi k, tada Y et al.
- Journal Title
  
  Clin Exp Dermatol 33
  
  Pages: 750-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591336
[Journal Article] Increased serum levels of a proliferation-inducing ligand in patients with bullous pemphigoid.2007
- Author(s)
  Watanabe R, Tada Y, et. al.
- Journal Title
  
  Journal of Dermatological Science 46
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790811
[Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques : is there interaction between dendritic cells and keratinocytes2007
- Author(s)
  Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K.
- Journal Title
  
  J Invest Dermatol 127巻
  
  Pages: 1915-1922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209039
[Journal Article] IL-18 enhances IFN-gamma-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes.2007
- Author(s)
  Kanda N, Tada Y, et. al.
- Journal Title
  
  European Journal of Immunology 37
  
  Pages: 338-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790811
[Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques: is there interaction between dendritic cells and keratinocytes?2007
- Author(s)
  Komine M, Tada Y, et. al.
- Journal Title
  
  Journal of Investigative Dermatology 127
  
  Pages: 1915-1922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790811
[Journal Article] Interleukin 12 production by monocytes from patients with psoriasis and its inhibition by ciclosporin A2006
- Author(s)
  Tada Y et al.
- Journal Title
  
  British Journal of Dermatology 154
  
  Pages: 1180-1183
- Data Source
  KAKENHI-PROJECT-18790811
[Journal Article] Identification and characterization of endogenous Langerin ligands in murine extracellular matrix2006
- Author(s)
  Tada Y et al.
- Journal Title
  
  Journal of Investigative Dermatology 126
  
  Pages: 1549-1558
- Data Source
  KAKENHI-PROJECT-18790811
[Journal Article] Type I interferons inhibit maturation and activation of mouse Langerhans cells.2005
- Author(s)
  Fujita H, Asahina A, Tada Y, Fujiwara H, Tamaki K
- Journal Title
  
  J Invest Dermatol 125(1)
  
  Pages: 126-133
- Data Source
  KAKENHI-PROJECT-17209039
[Presentation] 乾癬患者血清におけるT herper cell type 17誘導性サイトカインの検討2009
- Author(s)
  納さつき, 多田弥生, 神田奈緒子, 渡辺晋一
- Organizer
  第24回日本乾癬学会
- Place of Presentation
  東京
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-18591259
[Presentation] IL-1受容体拮抗薬とP2Y6拮抗薬の乾癬治療としての可能性について2009
- Author(s)
  多田弥生
- Organizer
  第24回日本乾癬学会
- Place of Presentation
  東海大学校友会館(東京都)
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-20591336
[Presentation] シンポジウム1乾癬患者血清におけるT herper cell type 17誘導性サイトカインの検討2009
- Author(s)
  納さつき, 多田弥生, 神田奈緒子, 渡辺晋一
- Organizer
  第24回日本乾癬学会
- Place of Presentation
  東京
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-18591259
[Presentation] Mouse epidermal keratinocytes express Sema4D/CD100 and its receptor CD72 is expressed on Langerhans cells.2008
- Author(s)
  Shimizu T, Tada Y et al.
- Organizer
  International Investigatve Dermatology 2008
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591336
[Presentation] Leukotriene B_4 enhances tumor necrosis factor-α-induced CCL27 production in human keratinocytes2007
- Author(s)
  Kanda N, Shimizu T, Tada Y, Watanabe S
- Organizer
  The 68th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-18591259
[Presentation] Leukotriene B_4 enhances tumor necrosis factor-α-induced CCL27 production in human keratinocytes2007
- Author(s)
  Kanda N, Shimizu T, Tada Y, Watanabe S
- Organizer
  The 68th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Los Angeles,USA
- Data Source
  KAKENHI-PROJECT-18591259
[Presentation] Prolactin enhances interferon-γ-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes.2007
- Author(s)
  Naoko Kanda, Teruo Shimizu, Yayoi Tada, Shinichi Watanabe
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-18591259
[Presentation] Leukotriene B4 enhances tumor necrosis factor-α-induced CCL27 production in human keratinocytes.2007
- Author(s)
  Kanda N, Shimizu T, Tada Y, Watanabe S
- Organizer
  The 68th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-18591259
[Presentation] Mouse epidermal keratinocytes express Sema4D/CD100 and its receptor CD72 is expressed on Langerhans cells.2007
- Author(s)
  Shimizu T, Tada Y, et. al.
- Organizer
  10th International Workshop on Langerhans cells.
- Place of Presentation
  Bern, Switzerland.
- Data Source
  KAKENHI-PROJECT-18790811
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1. TAMAKI Kunihiko (30010432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. ASAHINA Akihiko (50202601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. KOMINE Mayumi (00282632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. WATANABE Takahiro (30280960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANDA Naoko (50260493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. WATANABE Shinichi (90114719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. ONISHI Takamitsu (80233211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鎌田昌洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tada Yayoi 多田 弥生

TADA Yayoi 多田 弥生

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of keratinocyte-derived TARC production and its pathogenic role in pustular psoriasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of TARC-producing cells in pustular psoriasis and elucidation of pathogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examining the epidermal resident memory T cell of psoriasis model mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ganglioside as a drug for psoriasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

尿酸結晶のケラチノサイトへの作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Langerhans cell function by fibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of chemical mediators in the pathogenesis of psoriasis vulgaris and their therapeutical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TNFアルファによるランゲルハンス細胞の機能修飾Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of Langerhans cell stimulatory molecule and its application in skin disease therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Fingolimod ameliorates imiquimod-induced psoriasiform dermatitis by sequestrating interleukin-17-producing ?d T cells in secondary lymph nodes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Apremilast downregulates interleukin-17 production and induces splenic regulatory B cells and regulatory T cells in imiquimod-induced psoriasiform dermatitis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Patient preference for biologic treatments of psoriasis in Japan.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL36RN mutation.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The vitamin D3 analog, maxacalcitol, reduces psoriasiform skin inflammation by inducing regulatory T cells and downregulating IL-23 and IL-17 production.2018

Tada Yayoi 多田弥生

TADA Yayoi 多田弥生