KOBAYASHI Miwa 小林美和

Researcher Number	00341503
Affiliation *help	2007 – 2011 : University of Occupational and Environmental Health, Japan, 医学部, 講師 2007 – 2008 : 産業医大, 医学部, 講師 – 2007 : 産業医科大学, 医学部, 非常勤医師 2003 : University of Occupational and Environmental Health, Department of Dermatology, Assistant Instructor, 医学部, 助手
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology / Dermatology
Keywords	Principal Investigator 自然免疫 / 表皮ケラチノサイト / ヒスタミン / ナノマテリアル / 白癬菌 / β-glucan / サイトカイン / 表皮角化細胞 Except Principal Investigator 免疫 / 皮膚 … More

A response of pre-immune system of epidermal keratinocytesPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Miwa
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Occupational and Environmental Health, Japan
かゆみ過敏に関わるセマフォリン3a産生の表皮と真皮での相反性
- Principal Investigator
  
  TOKURA Yoshiki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  University of Occupational and Environmental Health, Japan
Does the epidermal keratinocyte recognize the pathogens, as for dermatophyte, by itself?Principal Investigator
- Principal Investigator
  
  KOBAYASHI Miwa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Occupational and Environmental Health, Japan
Immunomolecular mechanism of drug photosensitivity and screening for photoallergenicity of drugs
- Principal Investigator
  
  TOKURA Yoshiki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of Occupational and Environmental Health

All 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Expression of Toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes.2009
- Author(s)
  M Kobayashi, R Yoshiki, J Sakabe, K Kabashima, M Nakamura, Y Tokura.
- Journal Title
  
  British Journal of Dermatology 160
  
  Pages : 297-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790807
[Journal Article] Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes.2009
- Author(s)
  Kobayashi M
- Journal Title
  
  Br J Dermatol 160
  
  Pages : 297-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Journal Article] Expression of Toll-like receptor 2, NOD2, and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes2009
- Author(s)
  M. Kobayashi
- Journal Title
  
  British Journal of Dermatology 160
  
  Pages : 297-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790807
[Journal Article] Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes2009
- Author(s)
  Kobayashi M, Yoshiki R, Sakabe J, Kabashima K, Nakamura M, Tokura Y
- Journal Title
  
  Br J Dermatol 160
  
  Pages : 297-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Journal Article] Downmodulatory Effects of the Antihistaminic Drug Bepotastine on Cytokine/Chemokine Production and CD54 Expression in Human Keratinocytes.2009
- Author(s)
  Kobayashi M, Kabashima K, Nakamura M, Tokura Y
- Journal Title
  
  Skin Pharmacol Physiol 22
  
  Pages : 45-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Journal Article] 表皮ケラチノサイトのIL-8産生に対する真菌成分の影響と、抗真菌薬リラナフタートによる抑制効果.2008
- Author(s)
  小林美和、椛島健治,戸倉新樹.
- Journal Title
  
  日本医真菌学会雑誌 49
  
  Pages : 319-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790807
[Journal Article] Epidermal chemokines and modulation by antihistamines, antibiotics and antifungals2008
- Author(s)
  Tokura Y, Kobayashi M, Kabashima K
- Journal Title
  
  Exp Dermatol 17
  
  Pages : 81-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Journal Article] 表皮ケラチサイトのIL-8産生に対する真菌成分の影響と、抗真菌薬リラナフタートによる抑制効果2008
- Author(s)
  小林美和
- Journal Title
  
  日本医真菌学会雑誌 49
  
  Pages : 319-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790807
[Journal Article] Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis.2008
- Author(s)
  Koga C, Kabashitna K, Shiraishi N, Kobayashi M, Tokura Y
- Journal Title
  
  J Invest Dermatol 128
  
  Pages : 2625-2630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Journal Article] Cutaneous Hypersensitivities to Hapten Are Controlled by IFN-gamma-Upregulated Keratinocyte Th1 Chemokines and IFN-gamma-Downregulated Langerhans Cell Th2 Chemokines.2008
- Author(s)
  Mori T, Kabashima K, Yoshiki R, Sugita K, Shiraishi N, Onoue A, Kuroda E, Kobayashi M, Yamashita U, Tokura Y
- Journal Title
  
  J Invest Dermatol 128
  
  Pages : 1719-1727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Journal Article] Impaired Initiation of Contact Hypersensitivity by FTY720.2008
- Author(s)
  Nakashima D, Kabashima K, Sakabe JI, Sugita K, Kobayashi T, Yoshiki R, Tokura Y
- Journal Title
  
  J Invest Dermatol 128
  
  Pages : 2833-2841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659176
[Presentation] 二酸化チタンの表皮角化細胞に対する細胞傷害性の評価2011
- Author(s)
  小林美和
- Organizer
  第29回産業医科大学学会総会
- Place of Presentation
  ラマッツィーニホール福岡県北九州市
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-22791097
[Presentation] 二酸化チタンの表皮角化細胞に対する細胞傷害性の評価2011
- Author(s)
  小林美和
- Organizer
  第29回産業医科大学学会総会
- Place of Presentation
  ラマッツィーニホール(北九州市)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-22791097
[Presentation] Spicular form titanium dioxide induces IL-1 alpha/beta production of keratinocytes2010
- Author(s)
  Miwa Kobayashi
- Organizer
  第35回日本研究皮膚科学会総会学術大会
- Place of Presentation
  和歌山県民文化会館和歌山市
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22791097
[Presentation] Spicular form titanium dioxide induces IL-1 alpha/beta production of keratinocytes2010
- Author(s)
  小林美和
- Organizer
  第35回日本研究皮膚科学会総会学術大会
- Place of Presentation
  和歌山市(和歌山県民文化会館)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22791097
[Presentation] β-glucanとヒスタミン刺激によるケラチノサイトの自然免疫発動.2008
- Author(s)
  小林美和.
- Organizer
  第51回日本医真菌学会総会.
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-19790807
[Presentation] Histamine as a key enhancer for skin innate immunity to fungi.2008
- Author(s)
  M.Kobayashi.
- Organizer
  International Investigative Dermatology
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790807
[Presentation] ヒトケラチノサイトと繊維芽細胞におけるセマフォリン3Aの発現について2008
- Author(s)
  深町晶子, 白石紀子, 小林美和, 尾藤利憲, 椛島健治, 中村元信, 戸倉新樹
- Organizer
  日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-20659176
[Presentation] Semaphorin 3A production by human keratinocyte and fibroblast.2008
- Author(s)
  Fukamachi S, Shiraishi N, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
- Organizer
  18^<th> International Symposium of Itch
- Place of Presentation
  Tokyo
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20659176
[Presentation] Histamine as a key enhancer for skin innate immunity to fungi2008
- Author(s)
  M. Kobayashi
- Organizer
  International Investigative Dermatology 2008
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790807
[Presentation] Possible pathogenic role of Th17 Cells for atopic dermatitis.2008
- Author(s)
  Koga C, Kabashima K, Shiraishi N, Kobayashi M, Tokura Y
- Organizer
  International Investigative Dermatology2008
- Place of Presentation
  Kyoto
- Year and Date
  2008-05-14
- Data Source
  KAKENHI-PROJECT-20659176
[Presentation] Histamine and PAR-2 agonist upmodulate the production of cytokines/chemokines but modulate semaphorin 3A production in human keratinocyte.2008
- Author(s)
  Fukamachi S, Kabashima K, Shiraishi N, Kobayashii M, Tokura Y
- Organizer
  International Investigative Dermatology2008
- Place of Presentation
  Kyoto
- Year and Date
  2008-05-14
- Data Source
  KAKENHI-PROJECT-20659176
[Presentation] Augumentation of Intracellular TLR2 Expression by Peptidoglycan, β-Glucan, and Histamine in Human Keratinocytes.2007
- Author(s)
  Miwa Kobayashi
- Organizer
  37th Annual European Society for Dermatological Research Meeting
- Place of Presentation
  Zurich
- Data Source
  KAKENHI-PROJECT-19790807
[Presentation] Augumentation of Ineracellular TLR2 Expressuion byPeptidoglycan, β-Glucan, and Histamine in Human Keratinocytes2007
- Author(s)
  Kobayashi M
- Organizer
  37th Annual European Society for Dermatological research Meeting
- Place of Presentation
  Zurich
- Data Source
  KAKENHI-PROJECT-19790807
[Presentation] β-glucanとヒスタミン刺激によるケラチノサイトの自然免疫発動2007
- Author(s)
  小林美和
- Organizer
  第51回日本医真菌学会総会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-19790807

1. TOKURA Yoshiki (00172156)

# of Collaborated Projects : 2results

# of Collaborated Products : 10results
2. SAKABE Junichi

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. IZU Kunio (90330993)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 山元修 (70174779)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

KOBAYASHI Miwa 小林 美和

Research Projects

Research Products

Co-Researchers

A response of pre-immune system of epidermal keratinocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

かゆみ過敏に関わるセマフォリン3a産生の表皮と真皮での相反性

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Does the epidermal keratinocyte recognize the pathogens, as for dermatophyte, by itself?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunomolecular mechanism of drug photosensitivity and screening for photoallergenicity of drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of Toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Expression of Toll-like receptor 2, NOD2, and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes2009

Author(s)

Journal Title

Data Source

[Journal Article] Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes2009

Author(s)

Journal Title

Data Source

[Journal Article] Downmodulatory Effects of the Antihistaminic Drug Bepotastine on Cytokine/Chemokine Production and CD54 Expression in Human Keratinocytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] 表皮ケラチノサイトのIL-8産生に対する真菌成分の影響と、抗真菌薬リラナフタートによる抑制効果.2008

Author(s)

Journal Title

Data Source

[Journal Article] Epidermal chemokines and modulation by antihistamines, antibiotics and antifungals2008

Author(s)

Journal Title

Data Source

[Journal Article] 表皮ケラチサイトのIL-8産生に対する真菌成分の影響と、抗真菌薬リラナフタートによる抑制効果2008

Author(s)

Journal Title

Data Source

[Journal Article] Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis.2008

Author(s)

Journal Title

Data Source

[Journal Article] Cutaneous Hypersensitivities to Hapten Are Controlled by IFN-gamma-Upregulated Keratinocyte Th1 Chemokines and IFN-gamma-Downregulated Langerhans Cell Th2 Chemokines.2008

Author(s)

Journal Title

Data Source

[Journal Article] Impaired Initiation of Contact Hypersensitivity by FTY720.2008

Author(s)

Journal Title

Data Source

[Presentation] 二酸化チタンの表皮角化細胞に対する細胞傷害性の評価2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 二酸化チタンの表皮角化細胞に対する細胞傷害性の評価2011

Author(s)

KOBAYASHI Miwa 小林美和