Hamada Koichi 濱田浩一

… Alternative Names

Koichi Hamada 濱田浩一

HAMADA Koichi 濱田浩一

HAMADA Kouichi 濱田浩一

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Researcher Number	00343070
Affiliation (Current)	2025: 昭和薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2025: 昭和薬科大学, 薬学部, 講師 2019 – 2022: 昭和薬科大学, 薬学部, 講師 2015 – 2017: 昭和薬科大学, 薬学部, 講師 2016: 昭和薬科大学, 薬学系, 助教 2012 – 2014: 昭和薬科大学, 薬学部, 助教 … More 2010: Kumamoto University, エイズ学研究センター, 特定事業研究員 2009: Kyushu University, 生体防御医学研究所, 助教 2003 – 2005: 秋田大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related / Pathological medical chemistry / Infectious disease medicine / General medical chemistry / Circulatory organs internal medicine Except Principal Investigator Bioorganic chemistry / Dermatology
Keywords	Principal Investigator 生活習慣病 / IRBIT / 肥満 / 分化 / 細胞骨格 / 脂肪細胞 / 足細胞 / 腎障害 / 肥満治療薬 / アクチンフィラメント … More / GEF / 細胞分化 / ＩＲＢＩＴ / 細胞内ｐＨ / 転移 / 細胞内ｐH変化 / イオントランスポーター / 細胞移動 / 細胞内ｐH / HIV / ＰＩ３Ｋ／ＰＴＥＮ / 潜伏感染 / ＨＩＶ－１ / プロテアーゼ / 遺伝子改変マウス / 胎生致死 / 炎症 / セリンプロテアーゼ / 細胞死 / 細胞増殖 / 血液学 / 血管生物学 / 発生生物学 / 血管内皮細胞 / PI3K / PTEN … More Except Principal Investigator Stat3 / PTEN / プロモーター / 転写制御 / OsMYL2 / OsMYL1 / OsMYC2 / ジャスモン酸 / ファイトアレキシン / フラボノイド / イネ / 二次代謝産物 / 転写因子 / Keratinocyte / Oncogenesis / Cowden disease / 皮膚腫瘍 / STAT3ノックアウトマウス / Ptenノックアウトマウス / 角化細胞 / 発癌 / Cowden病 Less

Elucidation of the mechanism of renal injury in IRBIT-deficient micePrincipal Investigator
- Principal Investigator
  
  濱田浩一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Showa Pharmaceutical University
脂肪細胞の数と大きさを制御する新機構の解析Principal Investigator
- Principal Investigator
  
  濱田浩一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa Pharmaceutical University
Analysis of the function of IRBIT, a novel regulator in the number, size, and adipokine production of adipocytesPrincipal Investigator
- Principal Investigator
  
  Koichi Hamada
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa Pharmaceutical University
Long IRBIT regulates cell migration through modulating bicarbonate/chloride anion exchanger activity.Principal Investigator
- Principal Investigator
  
  HAMADA Koichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa Pharmaceutical University
Regulatory mechanisms on an inductive production of flavonoid-type phytoalexin in rice
- Principal Investigator
  
  Okada Kazunori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokyo
Development of new treatment strategies for HIV -1 infectionPrincipal Investigator
- Principal Investigator
  
  HAMADA Koichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Showa Pharmaceutical University
Rhomboid regulates innate immunity via TNFα signalingPrincipal Investigator
- Principal Investigator
  
  HAMADA Koichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
  Kyushu University
Roles for stat3 in carcinogenesis mouse model of Cowden disease
- Principal Investigator
  
  MANABE Motomu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Akita University
血管形成における脂質メディエーターの役割Principal Investigator
- Principal Investigator
  
  濱田浩一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Akita University

All 2022 2021 2020 2019 2017 2016 2012 2004 Other

All Journal Article Presentation Patent

[Journal Article] Acid Responsiveness of Emissive Morpholinyl Aminoquinolines and Their Use for Cell Fluorescence Imaging2022
- Author(s)
  Yuri Fukumoto, Tomohiro Umeno, Hina Kuramochi, Koichi Hamada, Shota Matsumoto, Noriko Suzuki, Kazuteru Usui, Akihiro Mizutania and Satoru Karasawa
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 20 Issue: 21 Pages: 4342-4351
- DOI
  10.1039/d2ob00546h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11712, KAKENHI-PROJECT-19K11776
[Journal Article] Both IRBIT and long-IRBIT bind to and coordinately regulate Cl -/HCO 3- exchanger AE2 activity through modulating the lysosomal degradation of AE22021
- Author(s)
  Itoh, R. Hatano, N. Murakami, M. Mitsumori, K. Kawasaki, S. Wakagi, T. Kanzaki, Y. Kojima, H. Kawaai, K. Mikoshiba, K. Hamada, K. Mizutani, A.
- Journal Title
  
  Sci Rep .
  
  Volume: 16 Issue: 1 Pages: 5990-5990
- DOI
  10.1038/s41598-021-85499-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11776, KAKENHI-PROJECT-19K12807, KAKENHI-PROJECT-20K06864, KAKENHI-PROJECT-18K02255, KAKENHI-PROJECT-21K15234
[Journal Article] Selective synthesis of substituted amino-quinoline derivatives by C-H activation and fluorescence evaluation of their lipophilicity-responsive properties2019
- Author(s)
  Fuchi Yasufumi、Sakuma Masaomi、Ohyama Kohei、Hagihara Ryusuke、Kohno Minaki、Hamada Koichi、Mizutani Akihiro、Karasawa Satoru
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 17723-17723
- DOI
  10.1038/s41598-019-53882-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07016, KAKENHI-PROJECT-19K11776, KAKENHI-PROJECT-17K08212
[Journal Article] The Phosphatidylinositol 3-Kinase p110α/PTEN Signaling Pathway Is Crucial for HIV-1 Entry2019
- Author(s)
  Hamada K, Maeda Y, Mizutani A, Okada S
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 1 Pages: 130-138
- DOI
  10.1248/bpb.b18-00801
- NAID
  130007542232
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09938, KAKENHI-PROJECT-19K08932, KAKENHI-PROJECT-19K11776
[Journal Article] 血液細胞における癌抑制遺伝子PTEN2004
- Author(s)
  濱田浩一, 佐々木雄彦, 仲野徹, 鈴木聡
- Journal Title
  
  血液・腫瘍科 48(2)
  
  Pages: 190-195
- Data Source
  KAKENHI-PROJECT-15790375
[Journal Article] PTENとアポトーシス2004
- Author(s)
  河原崎哲, 濱田浩一, 松田幸久, 佐々木雄彦, 仲野徹, 鈴木聡
- Journal Title
  
  Biotherapy 18(2)
  
  Pages: 151-160
- Data Source
  KAKENHI-PROJECT-15790375
[Journal Article] Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas2004
- Author(s)
  Horie Y, Suzuki A, Kataoka Ei, Sasaki T, Hamada K, et al.
- Journal Title
  
  JOURNAL OF CLINICAL INVESTIGATION 113(12)
  
  Pages: 1774-1783
- NAID
  120004837332
- Data Source
  KAKENHI-PROJECT-15790375
[Patent] 脂肪滴検出用試薬2019
- Inventor(s)
  唐澤悟、渕靖史、大山耕平、佐久間雅臣、濱田浩一、水谷顕洋
- Industrial Property Rights Holder
  唐澤悟、渕靖史、大山耕平、佐久間雅臣、濱田浩一、水谷顕洋
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K11776
[Presentation] IRBITによる脂肪細胞分化制御機構の解析2020
- Author(s)
  川端春奈、濱田浩一、河野未菜希、上野慎一郎、下田紗弥、田端彩子、水谷顕洋
- Organizer
  第140回日本薬学会
- Data Source
  KAKENHI-PROJECT-19K11776
[Presentation] IRBITファミリーによる細胞体積制御能の解析2019
- Author(s)
  伊藤諒, 川崎聡子, 濱田浩一, 波多野直哉, 水谷顕洋
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K11776
[Presentation] がん細胞におけるShroom3を介したIRBITファミリーの機能制御2017
- Author(s)
  五月女諒介、濱田浩一、三森皐介、伊藤諒、加藤心一郎、川崎聡子、波多野直哉、御子柴克彦、水谷顕洋
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K08318
[Presentation] Long-IRBITは陰イオン交換体の活性を調節して細胞移動を制御している2017
- Author(s)
  伊藤諒、濱田浩一、川崎聡子、御子柴克彦、水谷顕洋
- Organizer
  日本分子生物学会、日本生化学会　合同年次大会（神戸）
- Data Source
  KAKENHI-PROJECT-15K08318
[Presentation] Long-IRBIT plays a critical role in cell migration through binding to anion exchange 22016
- Author(s)
  Koichi Hamada, Ryo Ito, Kousuke Mitsumori, Shinichiro Kato, Naoya Hatano, Katsuhiko Mikoshiba, Akihiro Mizutani
- Organizer
  日米癌合同会議第10回
- Place of Presentation
  ハイアットリージェンシー、マウイ米国
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08318
[Presentation] Critical Role of the PI3K/PTEN/GSK-3 Signaling Pathway in HIV latent infected cells2012
- Author(s)
  濱田浩一、水谷顕洋、岡田誠治
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡(福岡市)
- Data Source
  KAKENHI-PROJECT-24591486
[Presentation] Biological roles of sakuranetin, a flavonoid specialized metabolite inductively produced in rice.
- Author(s)
  Satoshi Ogawa, Chie Yoshiga, Gen-ichiro Arimura, Takafumi Shimizu, Koji Miyamoto, Koichi Hamada, Yoko Nishizawa, Eiichi Minami, Hisakazu Yamane, Hideaki Nojiri, Kazunori Okada
- Organizer
  Plant Growth Regulation Society of America (PGRSA)
- Place of Presentation
  San Francisco, California, USA
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-26450136

1. MANABE Motomu (30138309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SUZUKI Akira (10311565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. INOUE Tae (10301061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Okada Kazunori (20312241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 唐沢悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 渕靖史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hamada Koichi 濱田 浩一

Koichi Hamada 濱田 浩一

HAMADA Koichi 濱田 浩一

HAMADA Kouichi 濱田 浩一

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of renal injury in IRBIT-deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脂肪細胞の数と大きさを制御する新機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the function of IRBIT, a novel regulator in the number, size, and adipokine production of adipocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Long IRBIT regulates cell migration through modulating bicarbonate/chloride anion exchanger activity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory mechanisms on an inductive production of flavonoid-type phytoalexin in rice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new treatment strategies for HIV -1 infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Rhomboid regulates innate immunity via TNFα signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles for stat3 in carcinogenesis mouse model of Cowden disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管形成における脂質メディエーターの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acid Responsiveness of Emissive Morpholinyl Aminoquinolines and Their Use for Cell Fluorescence Imaging2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Both IRBIT and long-IRBIT bind to and coordinately regulate Cl -/HCO 3- exchanger AE2 activity through modulating the lysosomal degradation of AE22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selective synthesis of substituted amino-quinoline derivatives by C-H activation and fluorescence evaluation of their lipophilicity-responsive properties2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Phosphatidylinositol 3-Kinase p110α/PTEN Signaling Pathway Is Crucial for HIV-1 Entry2019

Author(s)

Journal Title

DOI

Hamada Koichi 濱田浩一

Koichi Hamada 濱田浩一

HAMADA Koichi 濱田浩一

HAMADA Kouichi 濱田浩一