Kimura Y. Motoko 木村元子

… Alternative Names

KIMURA Motoko 木村元子

木村元子キムラモトコ

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Researcher Number	00345018
Other IDs
Affiliation (Current)	2024: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 千葉大学, 大学院医学研究院, 教授 2016 – 2020: 千葉大学, 大学院医学研究院, 准教授 2015: 千葉大学, 医学(系)研究科(研究院), 准教授 2014: 千葉大学, 医学(系)研究科(研究院), 特任准教授 2009: 千葉大学, 大学院・医学研究院, 助手 2006: 千葉大, 医学(系)研究科(研究院), 助手 2003 – 2005: 千葉大学, 大学院・医学研究院, 助手
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49030:Experimental pathology-related / Medium-sized Section 50:Oncology and related fields / Biological Sciences / Transformative Research Areas, Section (III) Except Principal Investigator Basic Section 56010:Neurosurgery-related / Transformative Research Areas, Section (III) / Basic Section 55040:Respiratory surgery-related / Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Biological Sciences
Keywords	Principal Investigator 胸腺 / CD69 / 免疫学 / 恒常性維持 / γδT細胞 / 抗腫瘍免疫 / NKT細胞 / 運命決定 / NKT2細胞 / iNKT細胞 … More / T細胞 / 細胞の運命決定 / NF-κB / Schnurri-2 / 抗腫瘍免疫応答 / 胎児期 / 組織常在性 / Neonatal T細胞 / 自然免疫型T細胞 / 組織特異性 / 腫瘍免疫 / アゴニスト選択 / 制御性T細胞 / 腫瘍微小環境 / がん抗原 / 中枢性免疫寛容 / ネオセルフ / 分化多様性 / CDR3 / TCRレパトア / 抗体療法 / CC69 / Myl9/12 / CD69リガンド / 抗腫瘍効果 / 疲弊 / 腫瘍浸潤T細胞 / がん免疫療法 / TCR / 前駆細胞 / 胸腺内分化 / 細胞運命決定 / Runx3 / Thpok / TCRシグナル / ヘルパー機能 / 胸腺内細胞分化 / 発生･分化 / apoptosis / memory T cell generation / NF_<-κ>B / GATA3 / Th2細胞分化 … More Except Principal Investigator 免疫療法 / 肺癌 / NKT細胞 / 膠芽腫 / 自己分子 / 免疫センサー / 抗腫瘍免疫抑制 / 慢性炎症 / 血小板 / Myosin light chain 9 / 鬱血 / 再疎通 / 皮下組織 / 瘢痕 / リンパ節 / リンパ管 / 線維化 / リンパ浮腫 / アジュバント効果 / NK細胞 / 糖類 / 免疫 / 糖鎖 / トランスレーショナルリサーチ / 癌 / 発生・分化 / 免疫学 Less

Understanding of physiological significance of neonatal T cellsPrincipal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Chiba University
Self-referential immune perception
- Principal Investigator
  
  山崎晶
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
Mechanisms of immune homeostasis and responses based on T cell mediated self-recognitionPrincipal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Chiba University
膠芽腫微小環境の理解に基づくNKT細胞標的治療の開発
- Principal Investigator
  
  本橋新一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Chiba University
Adjuvant effect of NK cells for NKT cell-based immunotherapy targeting lung cancer
- Principal Investigator
  
  Takami Mariko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Chiba University
Detection of the activity of chronic inflammation in subcutaneous tissue by blood sampling and visualization of the process of tissue fibrosis
- Principal Investigator
  
  秋田新介
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Chiba University
Impacts of central tolerance against tumor antigen on anti-tumor immune responsesPrincipal Investigator
- Principal Investigator
  
  Kimura Motoko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Chiba University
Molecular basis of immune homeostasis originating from the thymusPrincipal Investigator
- Principal Investigator
  
  KIMURA Motoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Chiba University
iNKT細胞の胸腺内分化運命決定とネオ・セルフ抗原の役割Principal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Research aimed at developing a new cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  Kimura Motoko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Chiba University
NKT cell-targeted cancer immunotherapy based on the comprehension of anti-tumor immune response in the lung cancer microenvironment
- Principal Investigator
  
  MOTOHASHI Shinichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Chiba University
アンコンベンショナルT細胞の分化と機能におけるネオ・セルフ抗原の関与とその役割Principal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Molecular mechanisms of T cell development and functional differentiation in the thymusPrincipal Investigator
- Principal Investigator
  
  KIMURA Motoko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Chiba University
T細胞の胸腺内分化におけるヘルパー機能獲得機構の解明Principal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Chiba University
NKT cell-based immunotherapy for cancer
- Principal Investigator
  
  NAKAYAMA Toshinori
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
巨大転写因子Shn-2によるNF-κB機能制御と免疫応答に関する研究Principal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University
アレルギー発症を制御するTh2細胞の形質維持機構に関する研究Principal Investigator
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University

[Book] 分子細胞免疫学原著第10版2022
- Author(s)
  Abul K. Abbas、Andrew H. Lichtman、Shiv Pillai、中尾篤人（翻訳　木村元子他）
- Total Pages
  650
- Publisher
  エルゼビア・ジャパン
- ISBN
  4860346769
- Data Source
  KAKENHI-PROJECT-20H03464
[Book] 分子細胞免疫学原著第10版2022
- Author(s)
  Abul K. Abbas、Andrew H. Lichtman、Shiv Pillai、中尾篤人（翻訳　木村元子他）
- Total Pages
  650
- Publisher
  エルゼビア・ジャパン
- ISBN
  4860346769
- Data Source
  KAKENHI-PLANNED-22H05189
[Book] Memory Th1/Th2 cell generation controlled by schnurri-2. M e m o r y T - C e l l s (edited by Maurizio Zanetti)2009
- Author(s)
  Nakayama, T., Kimura, Y.M.
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Increased Myosin light chain 9 expression during Kawasaki disease vasculitis2023
- Author(s)
  Kobayashi Hironobu、Kimura Motoko Y.、Hasegawa Ichita、Suganuma Eisuke、Ikehara Yuzuru、Azuma Kazuhiko、Ito Toshihiro、Ebata Ryota、Kurashima Yosuke、Kawasaki Yohei、Shiko Yuki、Saito Naoki、Iwase Hirotaro、Lee Youngho、Noval Rivas Magali、Arditi Moshe、Zuka Masahiko、Hamada Hiromichi、Nakayama Toshinori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.1036672
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464
[Journal Article] CD69 imposes tumor-specific CD8+ T cell fate in tumor-draining lymph nodes2023
- Author(s)
  Koyama-Nasu Ryo、Kimura Motoko Y.、 Kiuchi Masahiro、 Aoki Ami、Wang Yangsong, Mita Yukiyoshi、Hasegawa Ichita、Endo Yukihiro、Onodera Atsushi、Hirahara Kiyoshi、 Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Cancer Immunology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22H05189
[Journal Article] CD69 imposes tumor-specific CD8+ T cell fate in tumor-draining lymph nodes2023
- Author(s)
  Koyama-Nasu Ryo、Kimura Motoko Y.、 Kiuchi Masahiro、 Aoki Ami、Wang Yangsong, Mita Yukiyoshi、Hasegawa Ichita、Endo Yukihiro、Onodera Atsushi、Hirahara Kiyoshi、 Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Cancer Immunology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03464
[Journal Article] CD69-Myl9システムと炎症性疾患2022
- Author(s)
  木村元子、中山俊憲
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 77 Pages: 517-520
- Data Source
  KAKENHI-PLANNED-22H05189
[Journal Article] Clinical and Histological Effects of Partial Blood Flow Impairment in Vascularized Lymph Node Transfer2022
- Author(s)
  Shinsuke Akita, Yuzuru Ikehara, Minami Arai, Hideki Tokumoto, Yoshihisa Yamaji, Kazuhiko Azuma, Yoshitaka Kubota, Hideaki Haneishi, Motoko Y Kimura, Nobuyuki Mitsukawa
- Journal Title
  
  J Clin Med
  
  Volume: 11 Issue: 14 Pages: 4052-4052
- DOI
  10.3390/jcm11144052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09843, KAKENHI-PLANNED-22H05189, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464
[Journal Article] CD69-Myl9システムと炎症性疾患2022
- Author(s)
  木村元子、中山俊憲
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 77 Pages: 517-520
- Data Source
  KAKENHI-PROJECT-20H03464
[Journal Article] Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity2022
- Author(s)
  Iwamura Chiaki、Hirahara Kiyoshi、Kiuchi Masahiro、Ikehara Sanae、Azuma Kazuhiko、Shimada Tadanaga、Kuriyama Sachiko、Ohki Syota、Yamamoto Emiri、Inaba Yosuke、Shiko Yuki、Aoki Ami、Kokubo Kota、et al.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 33 Pages: 2203437119-2203437119
- DOI
  10.1073/pnas.2203437119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15484, KAKENHI-PROJECT-22K15485, KAKENHI-PLANNED-22H05189, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-20K08351, KAKENHI-PROJECT-20K08769, KAKENHI-PROJECT-21K20754
[Journal Article] The cellular and molecular basis of CD69 function in anti-tumor immunity2022
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Hasegawa Ichita、Endo Yukihiro、Nakayama Toshinori、Kimura Motoko Y
- Journal Title
  
  International Immunology
  
  Volume: 34 Issue: 11 Pages: 555-561
- DOI
  10.1093/intimm/dxac024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07234, KAKENHI-PLANNED-22H05189, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464
[Journal Article] 胸腺内iNKT細胞分化機構とCD69の役割2021
- Author(s)
  木村元子
- Journal Title
  
  血液内科
  
  Volume: 82(1)
- Data Source
  KAKENHI-PROJECT-20H03464
[Journal Article] IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation2021
- Author(s)
  Sarkar Murshed H.、Yagi Ryoji、Endo Yukihiro、Koyama-Nasu Ryo、Wang Yangsong、Hasegawa Ichita、Ito Toshihiro、Junttila Ilkka S.、Zhu Jinfang、Kimura Motoko Y.、Nakayama Toshinori
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 11 Pages: e0260204-e0260204
- DOI
  10.1371/journal.pone.0260204
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21537, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-21K07234, KAKENHI-PROJECT-19H05650
[Journal Article] Myosin Light Chain 9/12 Regulates the Pathogenesis of Inflammatory Bowel Disease2021
- Author(s)
  Yokoyama Masaya、Kimura Motoko Y.、Ito Toshihiro、Hayashizaki Koji、Endo Yukihiro、Wang Yangsong、Yagi Ryoji、Nakagawa Tomoo、Kato Naoya、Matsubara Hisahiro、Nakayama Toshinori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11
- DOI
  10.3389/fimmu.2020.594297
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20K21537, KAKENHI-PROJECT-19K16704, KAKENHI-PROJECT-21K07085
[Journal Article] CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69-Myl9 system2021
- Author(s)
  Nakayama Toshinori、Hirahara Kiyoshi、Kimura Motoko Y、Iwamura Chiaki、Kiuchi Masahiro、Kokubo Kota、Onodera Atsushi、Hashimoto Kahoko、Motohashi Shinichiro
- Journal Title
  
  International Immunology
  
  Volume: 33(12) Issue: 12 Pages: 699-704
- DOI
  10.1093/intimm/dxab053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PROJECT-19K16683, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-20K08769, KAKENHI-PROJECT-21K20754, KAKENHI-PROJECT-20KK0351
[Journal Article] 胸腺内iNKT細胞分化機構とCD69の役割2021
- Author(s)
  木村元子
- Journal Title
  
  血液内科
  
  Volume: 第82巻第1号
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Journal Article] 胸腺内iNKT細胞分化機構とCD69の役割2021
- Author(s)
  木村元子
- Journal Title
  
  血液内科
  
  Volume: 82
- Data Source
  KAKENHI-PROJECT-20K21537
[Journal Article] NKT細胞の新たな分化機構2021
- Author(s)
  木村元子
- Journal Title
  
  炎症と免疫
  
  Volume: 29 Pages: 288-291
- Data Source
  KAKENHI-PROJECT-20K21537
[Journal Article] T細胞性免疫のエフェクタ－機能のメカニズム　生体防御におけるT細胞の機能2020
- Author(s)
  中山俊憲、木村元子、八木良二
- Journal Title
  
  基礎免疫学　原著第6版ー免疫系の機能とその異常
  
  Volume: - Pages: 111-127
- Data Source
  KAKENHI-PROJECT-20H03464
[Journal Article] T細胞性免疫のエフェクタ－機能のメカニズム　生体防御におけるT細胞の機能2020
- Author(s)
  中山俊憲、木村元子、八木良二
- Journal Title
  
  基礎免疫学　原著第6版ー免疫系の機能とその異常
  
  Volume: - Pages: 111-127
- Data Source
  KAKENHI-PROJECT-20K21537
[Journal Article] Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation2020
- Author(s)
  Suzuki Akane S.、Yagi Ryoji、Kimura Motoko Y.、Iwamura Chiaki、Shinoda Kenta、Onodera Atsushi、Hirahara Kiyoshi、Tumes Damon J.、Koyama-Nasu Ryo、Iismaa Siiri E.、Graham Robert M.、Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1536-1536
- DOI
  10.3389/fimmu.2020.01536
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08769, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H02892, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-19K23838
[Journal Article] Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d‐independent manner2020
- Author(s)
  Aoki Takahiro、Takami Mariko、Takatani Tomozumi、Motoyoshi Kiwamu、Ishii Ayana、Hara Ayaka、Toyoda Takahide、Okada Reona、Hino Moeko、Koyama‐Nasu Ryo、Kiuchi Masahiro、Hirahara Kiyoshi、Kimura Motoko Y.、Nakayama Toshinori、Shimojo Naoki、Motohashi Shinichiro
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 7 Pages: 2223-2233
- DOI
  10.1111/cas.14428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07652, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H02892, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-19K18379
[Journal Article] Differentiation of Pathogenic Th17 Cells Is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis2020
- Author(s)
  Angelou Constance C.、Wells Alexandria C.、Vijayaraghavan Jyothi、Dougan Carey E.、Lawlor Rebecca、Iverson Elizabeth、Lazarevic Vanja、Kimura Motoko Y.、Peyton Shelly R.、Minter Lisa M.、Osborne Barbara A.、Pobezinskaya Elena L.、Pobezinsky Leonid A.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 3125-3125
- DOI
  10.3389/fimmu.2019.03125
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466, KAKENHI-PROJECT-20K21537, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-20H03464
[Journal Article] T細胞性免疫のエフェクタ－機能のメカニズム　生体防御におけるT細胞の機能2020
- Author(s)
  中山俊憲、木村元子、八木良二
- Journal Title
  
  基礎免疫学　原著第6版ー免疫系の機能とその異常
  
  Volume: - Pages: 111-127
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Journal Article] A new therapeutic target: the CD69-Myl9 system in immune responses2019
- Author(s)
  Kimura Motoko Y.、Koyama-Nasu Ryo、Yagi Ryoji、Nakayama Toshinori
- Journal Title
  
  Seminars in Immunopathology
  
  Volume: - Issue: 3 Pages: 349-358
- DOI
  10.1007/s00281-019-00734-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07165, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-18K07257, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18K19466
[Journal Article] Survival of Naive T Cells Requires the Expression of Let-7 miRNAs2019
- Author(s)
  Pobezinskaya Elena L.、Wells Alexandria C.、Angelou Constance C.、Fagerberg Eric、Aral Esengul、Iverson Elizabeth、Kimura Motoko Y.、Pobezinsky Leonid A.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 955-955
- DOI
  10.3389/fimmu.2019.00955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-18K19466
[Journal Article] Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology2019
- Author(s)
  Tumes, D., Hirahara, K., Papadopoulos, M., Shinoda, K., Onodera, A., Kumagai, J., Yip, KH., Pant, H., Kokubo, K., Masahiro, K., Aoki, A., Obata-Ninomiya, K., Yokoyoda, K., Endo, Y., Kimura, MY., Nakayama, T.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 0091-6749(19) Issue: 2 Pages: 30340-9
- DOI
  10.1016/j.jaci.2019.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383, KAKENHI-PUBLICLY-18H04665, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650
[Journal Article] CD69 prevents PLZFhi innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation2018
- Author(s)
  Kimura Motoko Y.、Igi Akemi、Hayashizaki Koji、Mita Yukiyoshi、Shinzawa Miho、Kadakia Tejas、Endo Yukihiro、Ogawa Satomi、Yagi Ryoji、Motohashi Shinichiro、Singer Alfred、Nakayama Toshinori
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3749-3749
- DOI
  10.1038/s41467-018-06283-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07165, KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18H02892
[Journal Article] The basis of T cell development and lineage choice in the thymus2018
- Author(s)
  Kimura, M.Y.
- Journal Title
  
  Chiba medical journal
  
  Volume: 94E Issue: 3 Pages: 19-23
- DOI
  10.20776/S03035476-94E-3-P19
- NAID
  120006489910
- URL
  https://opac.ll.chiba-u.jp/da/curator/105204/
- Year and Date
  2018-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787
[Journal Article] Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells2018
- Author(s)
  Mita Y, Kimura MY, Hayashizaki K, Koyama-Nasu R, Ito T, Motohashi S, Okamoto Y & Nakayama T
- Journal Title
  
  International Immunology
  
  Volume: 30 Issue: 12 Pages: 559-567
- DOI
  10.1093/intimm/dxy050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18H02892
[Journal Article] Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation2017
- Author(s)
  Kimura Motoko Y.、Hayashizaki Koji、Tokoyoda Koji、Takamura Shiki、Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Immunol. Rev.
  
  Volume: 278 Issue: 1 Pages: 87-100
- DOI
  10.1111/imr.12559
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15715, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K08524
[Journal Article] Myosin light chain 9 and 12 are functional ligands for CD69 that regulate airway inflammation2016
- Author(s)
  Hayashizaki, K., Kimura, M. Y., Tokoyoda, K., Hosokawa, H., Shinoda, K., Hirahara, K., Ichikawa, T., Onodera, A., Hanazawa, A., Iwamura, C., Kakuta, J., Muramoto, K., Motohashi, S., Tumes, D. J., Iinuma, T., Yamamoto, H., Ikehara, Y., Okamoto, Y., and Nakayama, T.
- Journal Title
  
  Sci. Immunol.
  
  Volume: 1 Issue: 3
- DOI
  10.1126/sciimmunol.aaf9154
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K08522, KAKENHI-PROJECT-15K08524
[Journal Article] Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors2016
- Author(s)
  Kimura, M. Y., Thomas, J., Tai, X., Guinter, T. I., Shinzawa, M., Etzenperger, R., Li, Z., Love, P., Nakayama, T., and Singer, A.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 17 Issue: 12 Pages: 1415-1423
- DOI
  10.1038/ni.3560
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K08524
[Journal Article] Methylation of Gata3 at Arg261 regulates transactivation of the Il5 gene in T helper 2 cells2015
- Author(s)
  Hosokawa, H., Kato, M., Tohyama, H., Tamaki, Y., Endo, Y., Kimura, M. Y., Tumes, D. J., Motohashi, S., Matsumoto, M., Nakayama, K. I., Tanaka, T., and Nakayama, T.
- Journal Title
  
  J Biol Chem
  
  Volume: in press Issue: 21 Pages: 13095-13103
- DOI
  10.1074/jbc.m114.621524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390239, KAKENHI-PROJECT-25670438, KAKENHI-PROJECT-15K08524
[Journal Article] Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function2015
- Author(s)
  Pobezinsky, L.A., Etzensperger, R., Jeurling, S., Alag, A., Kadakia, T., McCaughtry, T.M., Kimura, M.Y., Sharrow, S.O., Guinter, T.I., Feigenbaum, L. and Singer, A.
- Journal Title
  
  Nature Immunology
  
  Volume: 16 Issue: 5 Pages: 517-524
- DOI
  10.1038/ni.3146
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08524
[Journal Article] The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling.2014
- Author(s)
  Luckey MA, Kimura MY, Waickman AT, Feigenbaum L, Singer A and Park JH.: The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling.
- Journal Title
  
  Nat. Immunol
  
  Volume: 15 Pages: 638-645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26893033
[Journal Article] Chromatin remodeling at the Th2 cytokine gene loci in human type 2 helper T cells.2007
- Author(s)
  Kaneko, T., Hosokawa, H., Yamashita, M., Wang, C.R., Hasegawa, A., Kimura, Y.M., Kitajima, M., Kimura, F., Miyazaki, M., Nakayama, T.
- Journal Title
  
  M o l. I m m u n o l. 44
  
  Pages: 2249-2256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Schunurri-2 controls memory Th1 and Th2 cell number in vivo.2007
- Author(s)
  Kimura, Y
- Journal Title
  
  J. Immunol. 178
  
  Pages: 4926-4936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Schnurri-2 controls memory Th1 and Th2 cell numbers in vivo.2007
- Author(s)
  Kimura, Y.M., Iwamura, C., Suzuki, A., Miki, T., Hasegawa, A., Sugaya, K., Yamashita, M., Ishii, S., Nakayama, T.
- Journal Title
  
  J. I m m u n o l. 178
  
  Pages: 4926-4936
- NAID
  40016084081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Schnurri-2 controls the generation of memory Th1 and Th2 cells.2007
- Author(s)
  Kimura, Y. M.
- Journal Title
  
  13th International congress of Immunology.
  
  Pages: 475-479
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Crucial role of MLL for the maintenance of memory T helper type 2 cell responses.2006
- Author(s)
  Yamashita, M., Hirahara, K., Shinnakasu, R., Hosokawa, H., Norikane, S., Kimura, Y.M., Hasegawa, A., Nakayama, T.
- Journal Title
  
  I m m u n i t y 24
  
  Pages: 611-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Regulation of allergic airway inflammation through Toll -like receptor 4-mediated modification of mast cell function.2006
- Author(s)
  Nigo, I.Y., Yamashita, M., Hirahara, K., Shinnakasu, R., Inami, M., Kimura, M., Hasegawa, A., Kohno, Y., Nakayama, T.
- Journal Title
  
  P r o c. N a t l. A c a d. S c i. U S A 103
  
  Pages: 2286-2291
- NAID
  40015396097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Regulation of Th2 cell development by Polycomb group gene bmi-1 through the stabilization of GATA3.2006
- Author(s)
  Hosokawa, H., Kimura, Y.M., Shinnakasu, R., Suzuki, A., Miki, T., Koseki, H., van Lohuizen, M., Yamashita, M., Nakayama, T.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 7656-7664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Impaired GATA3-dependent chromatin remodeling and Th2 cell differentiation leading to attenuated allergic airway inflammation in aging mice.2006
- Author(s)
  Hasegawa, A., Miki, T., Hosokawa, H., Hossain, M.B., Shimizu, C., Hashimoto, K., Kimura, Y.M., Yamashita, M., Nakayama, T.
- Journal Title
  
  J. Immunol. 176
  
  Pages: 2546-2554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Differentiation of NK1 and NK2 cells.2005
- Author(s)
  Kimura, Y.M., Nakayama, T.
- Journal Title
  
  C r i t. R e v. I m m. 25
  
  Pages: 361-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Regulation of Th2 cell differentiation by murine Schnurri-22005
- Author(s)
  Kimura, Y.M.
- Journal Title
  
  J.Exp.Med. 201・3
  
  Pages: 397-408
- Data Source
  KAKENHI-PROJECT-17790317
[Journal Article] Regulation of T helper type 2 cell differentiation by murine Schnurri-2.2005
- Author(s)
  Kimura, M.Y.
- Journal Title
  
  J.Exp.Med. 201
  
  Pages: 397-408
- Data Source
  KAKENHI-PROJECT-15790248
[Journal Article] Differentiation of NK1 and NK2 cells.2005
- Author(s)
  Kimura, Y.M.
- Journal Title
  
  Crit.Rev.Imun. 25・5
  
  Pages: 361-374
- Data Source
  KAKENHI-PROJECT-17016010
[Journal Article] Differentiation of NK1 and NK2 cells.2005
- Author(s)
  Kimura, Y.M.
- Journal Title
  
  Crit.Rev.Imm. 25・5
  
  Pages: 361-374
- Data Source
  KAKENHI-PROJECT-17790317
[Journal Article] Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway.2005
- Author(s)
  Yamashita, M., Shinnakasu, R., Asou, H., Kimura, M., Hasegawa, A., Hashimoto, K., Hatano, N., Ogata, M., Nakayama, T.
- Journal Title
  
  J. B i o l. C h e m. 280
  
  Pages: 29409-29419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016010
[Presentation] CD69 regulates anti-tumor CD8T cell responses2023
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Endo Yukihiro、Hasegawa Ichita、Ueno Tatsuya、Mita Yukiyoshi、Motohashi Shinichiro、Nakayama Toshinori、Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 biology and pathology2023
- Author(s)
  Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] Role of CD69 on thymic regulatory T cell development2023
- Author(s)
  Endo Yukihiro、Ueno Tatsuya、Hasegawa Ichita、Wang Yangsong、Koyama-Nasu Ryo、 Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] Role of CD69 on thymic regulatory T cell development2023
- Author(s)
  Endo Yukihiro、Ueno Tatsuya、Hasegawa Ichita、Wang Yangsong、Koyama-Nasu Ryo、 Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 biology and pathology2023
- Author(s)
  Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] The essential role of central tolerance in tumor progression2023
- Author(s)
  Wang Yangsong、Koyama-Nasu Ryo、 Hasegawa Ichita、Endo Yukihiro、Kano Shunka, Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] The essential role of central tolerance in tumor progression2023
- Author(s)
  Wang Yangsong、Koyama-Nasu Ryo、 Hasegawa Ichita、Endo Yukihiro、Kano Shunka, Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69 regulates anti-tumor CD8T cell responses2023
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Endo Yukihiro、Hasegawa Ichita、Ueno Tatsuya、Mita Yukiyoshi、Motohashi Shinichiro、Nakayama Toshinori、Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] The essential role of central tolerance in tumor progression2022
- Author(s)
  Wang Yangsong、Koyama-Nasu Ryo、 Hasegawa Ichita、Endo Yukihiro、Kano Shunka, Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69 biology and pathology2022
- Author(s)
  Kimura Motoko Y.
- Organizer
  The 95th Annual Meeting of the Japanese Biochemical Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 biology and pathology2022
- Author(s)
  Kimura Motoko Y.
- Organizer
  The 95th Annual Meeting of the Japanese Biochemical Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] The essential role of central tolerance in tumor progression2022
- Author(s)
  Wang Yangsong、Koyama-Nasu Ryo、 Hasegawa Ichita、Endo Yukihiro、Kano Shunka, Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] 腫瘍特異的CD8T細胞の分化運命決定機構2022
- Author(s)
  那須亮、Wang Yangsong、長谷川一太、遠藤将大、中山俊憲、木村元子
- Organizer
  第31回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] 多彩な働きをするT細胞の分化・機能と疾患制御2022
- Author(s)
  木村元子
- Organizer
  第6回千葉大学膜タンパク質研究センター×量子科学技術研究開発機構　量子生命科学研究所合同勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21537
[Presentation] Ｔ細胞を中心とした抗腫瘍免疫応答の包括的理解とその治療戦略基盤の創生2022
- Author(s)
  木村元子
- Organizer
  千葉大学　国際高等研究基幹（IAAR)キックオフシンポジウム
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] 多彩な働きをするT細胞の分化・機能と疾患制御2022
- Author(s)
  木村元子
- Organizer
  第6回千葉大学膜タンパク質研究センター×量子科学技術研究開発機構　量子生命科学研究所合同勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] Ｔ細胞を中心とした抗腫瘍免疫応答の包括的理解とその治療戦略基盤の創生2022
- Author(s)
  木村元子
- Organizer
  千葉大学　国際高等研究基幹（IAAR)キックオフシンポジウム
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] 胸腺内制御性R細胞分化におけるCD69の役割2022
- Author(s)
  遠藤将大、上野達矢、長谷川一太、Wang Yangsong、那須亮、木村元子
- Organizer
  第31回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] 胸腺内制御性R細胞分化におけるCD69の役割2022
- Author(s)
  遠藤将大、上野達矢、長谷川一太、Wang Yangsong、那須亮、木村元子
- Organizer
  第31回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69 regulates anti-tumor CD8T cell responses2022
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Endo Yukihiro、Hasegawa Ichita、Ueno Tatsuya、Mita Yukiyoshi、Motohashi Shinichiro、Nakayama Toshinori、Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] Role of CD69 on thymic regulatory T cell development2022
- Author(s)
  Endo Yukihiro、Ueno Tatsuya、Hasegawa Ichita、Wang Yangsong、Koyama-Nasu Ryo、 Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 regulates anti-tumor CD8T cell responses2022
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Endo Yukihiro、Hasegawa Ichita、Ueno Tatsuya、Mita Yukiyoshi、Motohashi Shinichiro、Nakayama Toshinori、Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] Role of CD69 on thymic regulatory T cell development2022
- Author(s)
  Endo Yukihiro、Ueno Tatsuya、Hasegawa Ichita、Wang Yangsong、Koyama-Nasu Ryo、 Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] 腫瘍特異的CD8T細胞の分化運命決定機構2022
- Author(s)
  那須亮、Wang Yangsong、長谷川一太、遠藤将大、中山俊憲、木村元子
- Organizer
  第31回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69-Myl9システムと炎症制御2021
- Author(s)
  木村元子, 横山将也, 小林弘信, 林﨑浩史, 遠藤将大, Wang Yangsong, 長谷川一太, 那須亮, 中山俊憲
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69 regulates anti-tumor immunity2021
- Author(s)
  Kimura M., Nasu R., Mita Y., Wang Y., Endo Y., Hasegawa I., Motohashi S., Nakayama T.
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69 regulates anti-tumor immunity2021
- Author(s)
  Kimura M., Nasu R., Mita Y., Wang Y., Endo Y., Hasegawa I., Motohashi S., Nakayama T.
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21537
[Presentation] CD69-Myl9システムと炎症制御2021
- Author(s)
  木村元子, 横山将也, 小林弘信, 林﨑浩史, 遠藤将大, Wang Yangsong, 長谷川一太, 那須亮, 中山俊憲
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21537
[Presentation] CD69 Biology and Pathology2020
- Author(s)
  Kimura M.Y., Koyama-Nasu, R., Mita Y., Hayashizaki, K. and Nakayama T.
- Organizer
  11th International Symposium of IFReC, Immunology at the Forefront
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Presentation] CD69 Biology and Pathology2020
- Author(s)
  Kimura M.Y., Koyama-Nasu, R., Mita Y., Hayashizaki, K. and Nakayama T.
- Organizer
  1th International Symposium of IFReC, Immunology at the Forefront
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Presentation] CD69 Biology and Pathology2020
- Author(s)
  Kimura M.Y., Koyama-Nasu, R., Mita Y., Hayashizaki, K. and Nakayama T.
- Organizer
  11th International Symposium of IFReC, Immunology at the Forefront
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21537
[Presentation] CD69 Biology and Pathology2020
- Author(s)
  Kimura M.Y., Koyama-Nasu, R., Mita Y., Hayashizaki, K. and Nakayama T.
- Organizer
  11th International Symposium of IFReC, Immunology at the Forefront
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] CD69 Biology and Pathology2020
- Author(s)
  Kimura M.Y., Koyama-Nasu, R., Mita Y., Hayashizaki, K. and Nakayama T.
- Organizer
  11th International Symposium of IFReC, Immunology at the Forefront
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03464
[Presentation] CD69 regulates T cell exhaustion at the tumor microenvironment2019
- Author(s)
  Kimura M.Y.
- Organizer
  First Chiba University - University of Toronto workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] がん免疫療法の新たなターゲットとしてのCD69の可能性2019
- Author(s)
  木村元子、那須亮、三田恭義、中山俊憲
- Organizer
  第２３回日本がん免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Presentation] CD69 regulates T cell exhaustion at the tumor microenvironment2019
- Author(s)
  Kimura M.Y.
- Organizer
  3rd Annual CU-UCSD cMAV Symposium, UC San Diego, San Diego
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] CD69 regulates residency time of developing thymocytes that is important for NKT2 cell differentiation in the thymus2019
- Author(s)
  Kimura M.Y., Hayashizaki, K., Yagi, R., Endo, Y., Motohashi, S. and Nakayama, T.
- Organizer
  EMBO Workshop ThymE: T cell and thymus biology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Presentation] がん免疫療法の新たなターゲットとしてのCD69の可能性2019
- Author(s)
  木村元子、那須亮、三田恭義、中山俊憲
- Organizer
  第２３回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] CD69 regulates residency time of developing thymocytes that is important for NKT2 cell differentiation in the thymus2019
- Author(s)
  Kimura M.Y., Hayashizaki, K., Yagi, R., Endo, Y., Motohashi, S. and Nakayama, T.
- Organizer
  EMBO Workshop ThymE: T cell and Thymus biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] Inhibition of acetyl-CoA carboxylase enhances memory Th2 cell generation and Th2 mediated anti-tumor immunity.2019
- Author(s)
  Koyama-Nasu R., Endo Y., Ito T., Kanno T., Nakajima T., Kimura M.Y. and Nakayama T.
- Organizer
  第２３回日本がん免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Presentation] CD69 regulates T cell exhaustion at the tumor microenvironment2019
- Author(s)
  Kimura M.Y.
- Organizer
  3rd Annual CU-UCSD cMAV Symposium, UC San Diego, San Diego
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] Inhibition of acetyl-CoA carboxylase enhances memory Th2 cell generation and Th2 mediated anti-tumor immunity2019
- Author(s)
  Koyama-Nasu R., Endo Y., Ito T., Kanno T., Nakajima T., Kimura M.Y. and Nakayama T.
- Organizer
  第２３回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] CD69 regulates T cell exhaustion at the tumor microenvironmen2019
- Author(s)
  Kimura M.Y.
- Organizer
  First Chiba University-University of Toronto workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04800
[Presentation] The role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura M.Y., Igi, A., Hayashizaki K., Mita Y., Endo, Y., Ogawa, S., Singer, A. and Nakayama, T.
- Organizer
  KAI International Meeting 2018, Sejong University Convention Center, Seoul, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] Crucial role for CD69 in anti-tumor immunity2018
- Author(s)
  Mita, Y., Kimura, M., Nasu, R., Motohashi, S., Okamoto, Y., Nakayama, T.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02892
[Presentation] CD69による抗腫瘍免疫制御2018
- Author(s)
  三田恭義、木村元子、那須亮、本橋新一郎、岡本美孝、中山俊憲
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] 胸腺内細胞分化におけるCD69の重要性2018
- Author(s)
  木村元子
- Organizer
  Kyoto T Cell Conference 第28回学術集会
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] CD69-Myl9 system regulates pathogenesis of inflammatory disorders2018
- Author(s)
  Kimura M.Y., Hayashizaki K. and Nakayama T
- Organizer
  The 2nd Chiba University-UC San Diego Symposium "Mucosal Immunology, Allergy and Vaccine"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] 胸腺内細胞分化におけるCD69の重要性2018
- Author(s)
  木村元子、伊木明美、林崎浩史、遠藤将大、中山俊憲
- Organizer
  第83回日本インターフェロン・サイトカイン学術集会 (大会長特別枠講演)
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] Role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura M.Y., Hayashizaki, K., Yagi, R., Endo, Y., Motohashi, S. and Nakayama, T.
- Organizer
  The 47th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] The role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura M.Y.
- Organizer
  2018 NIH Thymus symposium, Bethesda
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] CD69-Myl9 system regulates pathogenesis of inflammatory disorders2018
- Author(s)
  Kimura M.Y., Hayashizaki K. and Nakayama T.
- Organizer
  The 2nd Chiba University-UC San Diego Symposium "Mucosal Immunology, Allergy and Vaccine"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] 胸腺内細胞分化におけるCD69の重要性2018
- Author(s)
  木村元子、伊木明美、林崎浩史、遠藤将大、中山俊憲
- Organizer
  第83回日本インターフェロン・サイトカイン学術集会＊大会長特別枠講演
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] CD69 regulates T-cell exhaustionin the tumor microenvironment2018
- Author(s)
  Kimura M.Y., Mita Y. and Nakayama, T.
- Organizer
  Pusan National University, Busan, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] CD69-Myl9 system regulates pathogenesis of inflammatory disorders2018
- Author(s)
  Kimura M.Y., Hayashizaki K. and Nakayama T.
- Organizer
  The 2nd Chiba University-UC San Diego Symposium "Mucosal Immunology, Allergy and Vaccine"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] 胸腺内細胞分化におけるCD69の重要性2018
- Author(s)
  木村元子
- Organizer
  Kyoto T Cell Conference 第28回学術集会
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] Role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura M.Y., Hayashizaki, K., Yagi, R., Endo, Y., Motohashi, S. and Nakayama, T.
- Organizer
  The 47th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] CD69による抗腫瘍免疫制御2018
- Author(s)
  三田恭義、木村元子、那須亮、本橋新一郎、岡本美孝、中山俊憲
- Organizer
  第２２回日本がん免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] The role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura M.Y., Igi, A., Hayashizaki K., Mita Y., Endo, Y., Ogawa, S., Singer, A. and Nakayama, T.
- Organizer
  KAI International Meeting 2018, Sejong University Convention Center, Seoul, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] CD69による抗腫瘍免疫制御2018
- Author(s)
  三田恭義、木村元子、那須亮、本橋新一郎、岡本美孝、中山俊憲
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] The role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura M.Y.
- Organizer
  2018 NIH Thymus symposium, Bethesda, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] CD69-Myl9 system regulates pathogenesis of inflammatory disorders2018
- Author(s)
  Kimura M.Y., Hayashizaki K., Nakayama T.
- Organizer
  The 2nd Chiba University-UC San Diego Symposium "Mucosal Immunology, Allergy and Vaccine"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] CD69 regulates T-cell exhaustionin the tumor microenvironment2018
- Author(s)
  Kimura M.Y., Mita Y. and Nakayama, T.
- Organizer
  Pusan National University, Busan, Korea
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] Role of CD69 on iNKT cell development in the thymus2018
- Author(s)
  Kimura, M. Y., Hayashizaki, K., Yagi, R., Endo, Y., Motohashi, S., Nakayama, T.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02892
[Presentation] CD69による抗腫瘍免疫制御2018
- Author(s)
  三田恭義、木村元子、那須亮、本橋新一郎、岡本美孝、中山俊憲
- Organizer
  第２２回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K19466
[Presentation] Myosin light chain 9 and 12 are functional ligands for CD69 that regulate airway inflammation2017
- Author(s)
  Kimura M.Y., Hayashizaki K., Nakayama T.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation.2017
- Author(s)
  Hayashizaki, K., Kimura, M.Y., Igi, A., and Nakayama, T.
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  京都大学医学部・芝蘭会館（京都府京都市）
- Year and Date
  2017-03-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Myosin light chain 9 and 12 are functional ligands for CD69 that regulate airway inflammation2017
- Author(s)
  Kimura M.Y., Hayashizaki K. and Nakayama T.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05787
[Presentation] Timing and duration of MHC-I positive selection signals in the thymus reveal a novel compensatory signaling mechanism that prevents lineage fate errors.2016
- Author(s)
  Kimura, M.Y., Nakayama, T., and Singer, A.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Timing and duration of MHC-I positive selection and CD8 lineage choice in the thymus.2016
- Author(s)
  Kimura M.Y.
- Organizer
  NIH Thymus Symposium
- Place of Presentation
  NIH, Bethesda, USA
- Year and Date
  2016-12-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Strong TCR signaling prolongs lineage uncertainty during MHC-I specific positive selection2015
- Author(s)
  Kimura, M., Nakayama, T., and Singer, A.
- Organizer
  Immunology 2015　AAI Annual Meeting
- Place of Presentation
  New Orleans (U.S.A.)
- Year and Date
  2015-05-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Roles of IL-2 on Th9 cell differentiation2015
- Author(s)
  Sarkar, H. M., Yagi, R., Nakajima, T., Kimura, M., Nakayama, T., and Zhu, J.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター　(北海道札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Molecular basis for acquisition of helper function during thymocyte development2015
- Author(s)
  Motoko Y. Kimura, Toshinori Nakayama and Alfred Singer
- Organizer
  第25回 Kyoto T Cell Conference
- Place of Presentation
  京都大学芝蘭会館　(京都府京都市）
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Molecular basis for acquisition of helper function during thymocyte development2015
- Author(s)
  Motoko Y. Kimura, Miho Shinzawa, Ruth Etzensperger, Ryoji Yagi, Koji Hayashizaki, Akemi Igi, Toshinori Nakayama and Alfred Singer
- Organizer
  Venice Thymus Meeting 2015
- Place of Presentation
  Venice (Italy)
- Year and Date
  2015-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08524
[Presentation] Hayashizaki, K., Singer, A., and Nakayama, T.: Molecular basis for functional (helper versus cytotoxic) lineage fate decisions during thymocyte development.
- Author(s)
  Kimura, M
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26893033

1. MOTOHASHI Shinichiro (60345022)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. NAKAYAMA Toshinori (50237468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. Takami Mariko (60770906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 秋田新介 (00436403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 三川信之 (40595196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 山崎晶 (40312946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三宅健介 (60229812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 和泉自泰 (70622166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 瀬川勝盛 (20542971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 改正恒康 (60224325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 安友康二 (30333511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 浅野謙一 (10513400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 堀昌平 (50392113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 那須亮 (30466859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
15. 小林正芳 (10867857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 岩立康男 (70272309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HIRAHARA kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. ONODERA atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. HOSOKAWA hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. SHINODA kenta

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. IWAMURA Chiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 八木良二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 林崎浩史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 田中知明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 小久保幸太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Y. Motoko 木村 元子

KIMURA Motoko 木村 元子

木村 元子 キムラ モトコ

Research Projects

Research Products

Co-Researchers

Understanding of physiological significance of neonatal T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Self-referential immune perception

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Mechanisms of immune homeostasis and responses based on T cell mediated self-recognitionPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

膠芽腫微小環境の理解に基づくNKT細胞標的治療の開発

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Adjuvant effect of NK cells for NKT cell-based immunotherapy targeting lung cancer

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Detection of the activity of chronic inflammation in subcutaneous tissue by blood sampling and visualization of the process of tissue fibrosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Impacts of central tolerance against tumor antigen on anti-tumor immune responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular basis of immune homeostasis originating from the thymusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

iNKT細胞の胸腺内分化運命決定とネオ・セルフ抗原の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research aimed at developing a new cancer immunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NKT cell-targeted cancer immunotherapy based on the comprehension of anti-tumor immune response in the lung cancer microenvironment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アンコンベンショナルT細胞の分化と機能におけるネオ・セルフ抗原の関与とその役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of T cell development and functional differentiation in the thymusPrincipal Investigator

Principal Investigator

Kimura Y. Motoko 木村元子

KIMURA Motoko 木村元子

木村元子キムラモトコ

[Book] 分子細胞免疫学原著第10版2022

[Book] 分子細胞免疫学原著第10版2022