Kinugawa Koichiro 絹川弘一郎

… Alternative Names

絹川弘一郎キヌガワコウイチロウ

KINUGAWA Koh-ichiro 絹川弘一郎

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Researcher Number	00345216
Affiliation (Current)	2022: 富山大学, 学術研究部医学系, 教授
Affiliation (based on the past Project Information) *help	2021: 富山大学, 学術研究部医学系, 教授 2015 – 2018: 富山大学, 大学院医学薬学研究部(医学), 教授 2002 – 2005: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 心不全 / 甲状腺ホルモン / 心筋細胞 / 心肥大 / p38 MAPキナーゼ / 甲状腺ホルモンレセプター / 胎児型遺伝子発現 / アデノウィルス / ラット / 遺伝子発現 … More / thyroid hormone / cardiac myocytes / cardiac hypertrophy / p38 MAK kinase / thyroid hormone receptor / fetal gene program / adenovirus / rat / aqauporin 2 / responders / tolvaptan / renal dysfunction / aquaporin 2 / heart failure / responder / 心腎連関 / アクアポリン２ / トルバプタン / 腎機能障害 / アクアポリン … More Except Principal Investigator 心不全 / 胎児型遺伝子 / 肺高血圧 / Ca^<2+> transient / heart failure / angiotensin II / 自然免疫 / Toll-like受容体 / 心筋細胞 / アンジオテンシンII / 心室間相互作用 / Ca^<2+>transient / innate immunity / Toll-like receptors / cardiac myocytes / fetal genes / pulmonary hypertension / 肥大 / モノクロタリン / 胎児遺伝子 / アンギオテンシンII / バルサルタン / カルベジロール / 筋小胞体 / 心肥大 / BNP / hypertrophy / pulmonary arterial hypertension / monocrotaline / fetal gene / valsartan / carvedilol / 後天性フォンビルブランド症候群 / 機械的補助循環 / 心原性ショック / 血管新生 / 重症心不全 / 消化管出血 Less

重症心不全患者における消化管出血発症のメカニズムとアンジオポエチン2の関連
- Principal Investigator
  
  中村牧子
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  University of Toyama
Long-term prognosis of aquaporin-defined responders for tolvaptan in heart failure and renal dysfunctionPrincipal Investigator
- Principal Investigator
  
  Kinugawa Koichiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Toyama
Therapeutic investigation of the factors leading to the molecular abnormalities in heart failure
- Principal Investigator
  
  YAO Atsushi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
A novel strategy for the treatment of congestive heart failure utilizing thyroid hormone signalingPrincipal Investigator
- Principal Investigator
  
  KINUGAWA Koichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Roles of innate immunity in genesis of heart failure
- Principal Investigator
  
  TAKAHASHI Toshiyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo

All 2022 2019 2018 2016 2015 2005

All Journal Article Presentation

[Journal Article] Impact of the Severity of Acquired von Willebrand Syndrome on the Short-Term Prognosis in Patients with Temporary Mechanical Circulatory Support2022
- Author(s)
  Nakamura Makiko、Imamura Teruhiko、Ueno Hiroshi、Kinugawa Koichiro
- Journal Title
  
  Medicina
  
  Volume: 58 Pages: 238-238
- DOI
  10.3390/medicina58020238
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08074
[Journal Article] Update of acute and long-term tolvaptan therapy2019
- Author(s)
  Imamura Teruhiko、Kinugawa Koichiro
- Journal Title
  
  Journal of Cardiology
  
  Volume: 73 Pages: 102-107
- DOI
  10.1016/j.jjcc.2018.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Novel Risk Score Efficiently Prevents Tolvaptan-Induced Hypernatremic Events in Patients With Heart Failure2018
- Author(s)
  Kinugawa Koichiro、Sato Naoki、Inomata Takayuki、Yasuda Moriyoshi、Shibasaki Yoshiyuki、Shimakawa Toshiyuki
- Journal Title
  
  Circulation Journal
  
  Volume: 82 Issue: 5 Pages: 1344-1350
- DOI
  10.1253/circj.cj-17-0986
  10.1253/circj.CJ-17-0986
- NAID
  130006725971
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Tolvaptan Improves Prognosis in Responders with Acute Decompensated Heart Failure by Reducing the Dose of Loop Diuretics2018
- Author(s)
  Nakamura Makiko、Sunagawa Osahiko、Kinugawa Koichiro
- Journal Title
  
  International Heart Journal
  
  Volume: 59 Issue: 1 Pages: 87-93
- DOI
  10.1536/ihj.17-099
- NAID
  130006321433
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Effects of Tolvaptan on Volume Overload in Patients with Heart Failure2018
- Author(s)
  Kinugawa Koichiro、Sato Naoki、Inomata Takayuki
- Journal Title
  
  International Heart Journal
  
  Volume: 59 Issue: 6 Pages: 1368-1377
- DOI
  10.1536/ihj.18-119
- NAID
  130007521919
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Tolvaptan Prolongs Blockage of the Vasopressin Type II Receptor Over 24 Hours in Responders With Stage D Heart Failure2016
- Author(s)
  Imamura T, Kinugawa K, Komuro I.
- Journal Title
  
  International Heart Journal
  
  Volume: 57 Issue: 1 Pages: 41-46
- DOI
  10.1536/ihj.15-297
- NAID
  130005120983
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Tolvaptan Reduces Long-Term Total Medical Expenses and Length of Stay in Aquaporin-Defined Responders2016
- Author(s)
  Imamura, T. Kinugawa, K. Nitta, D. Komuro, I.
- Journal Title
  
  International Heart Journal
  
  Volume: 57 Issue: 5 Pages: 593-599
- DOI
  10.1536/ihj.16-007
- NAID
  130005266557
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Tolvaptan Improves the Long-Term Prognosis in Patients With Congestive Heart Failure With Preserved Ejection Fraction as Well as in Those With Reduced Ejection Fraction2016
- Author(s)
  Imamura, T. Kinugawa, K.
- Journal Title
  
  International Heart Journal
  
  Volume: 57 Issue: 5 Pages: 600-606
- DOI
  10.1536/ihj.16-023
- NAID
  130005266611
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Urine Aquaporin-2: A Promising Marker of Response to the Arginine Vasopressin Type-2 Antagonist, Tolvaptan in Patients with Congestive Heart Failure.2016
- Author(s)
  Imamura T, Kinugawa K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 17
- DOI
  10.3390/ijms17010105
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Ratio of urine and blood urea nitrogen concentration predicts the response of tolvaptan in congestive heart failure.2015
- Author(s)
  Shimizu K, Doi K, Imamura T, Noiri E, Yahagi N, Nangaku M, Kinugawa K.
- Journal Title
  
  Nephrology (Carlton, Vic).
  
  Volume: 20 Pages: 405-12
- DOI
  10.1111/nep.12406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Successful Treatment of Intractable Fluid Retention Using Tolvaptan After Treatment for Postoperative Mediastinitis in a Patient With a Left Ventricular Assist Device2015
- Author(s)
  Kimura M, Nawata K, Kinoshita O, Hatano M, Imamura T, Kinugawa K, Ono M.
- Journal Title
  
  International Heart Journal
  
  Volume: 56 Issue: 5 Pages: 574-577
- DOI
  10.1536/ihj.14-412
- NAID
  130005102114
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Mid-Term Administration of Tolvaptan Improves Renal Function Accompanied by Dose-Reduction in Furosemide in Aquaporin-Defined Responders2015
- Author(s)
  Imamura T, Kinugawa K.
- Journal Title
  
  International Heart Journal
  
  Volume: 56 Issue: 6 Pages: 686-687
- DOI
  10.1536/ihj.15-298
- NAID
  130005113066
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09065
[Journal Article] Thyroid hormone induces cardiac myocyte hypertrophy in a TRα_1-specific manner that requirea TAK1 and p38 MAPK.2005
- Author(s)
  Kinugawa et al.
- Journal Title
  
  Mol Endocrinol (in press)
- Data Source
  KAKENHI-PROJECT-15590723
[Journal Article] Thyroid hormone induces cardiac myocyte hypertrophy in a TR_<α1>-specific manner that requires TAK1 and p38 MAPK.2005
- Author(s)
  Kinugawa et al.
- Journal Title
  
  Mol Endocrinol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590723
[Journal Article] Difference in Abnormal Ca2+ Regulation Between Left and Right Ventricles in Rats with Monocrotaline-induced Pulmonary Hypertension2005
- Author(s)
  Ogawa H, Hotta Y, Yao A, Kinugawa K, Nagai R, Kohmoto O.
- Journal Title
  
  Journal of Cardiac Failure 11(Supplement)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590662
[Journal Article] Thyroid hormone induces cardiac myocyte hypertrophy in a TRα_1-specific manner that requires TAK1 and p38 MAPK.2005
- Author(s)
  Kinugawa et al.
- Journal Title
  
  Mol Endocrinol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590723
[Presentation] Acquired von Willebrand syndrome during temporary mechanical circulatory support2022
- Author(s)
  中村牧子, 今村輝彦, 上野博志, 絹川弘一郎
- Organizer
  第86回日本循環器学会
- Data Source
  KAKENHI-PROJECT-21K08074
[Presentation] Who Needs Longer Treatment of Tolvaptan? ―An Interim Analysis from the Samsca Post-Marketing Surveillance in Heart Failure (SMILE Study) ―.2016
- Author(s)
  Kinugawa K, Inomata T, Sato N, Yasuda M, Shimakawa T, Bando K.
- Organizer
  The 80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台
- Year and Date
  2016-03-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09065

1. YAO Atsushi (70372381)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. TAKAHASHI Toshiyuki (40236302)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 今村輝彦 (80746652)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 中村牧子 (80860262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 碓井伸一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kinugawa Koichiro 絹川 弘一郎

絹川 弘一郎 キヌガワ コウイチロウ

KINUGAWA Koh-ichiro 絹川 弘一郎

Research Projects

Research Products

Co-Researchers

重症心不全患者における消化管出血発症のメカニズムとアンジオポエチン2の関連

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Long-term prognosis of aquaporin-defined responders for tolvaptan in heart failure and renal dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic investigation of the factors leading to the molecular abnormalities in heart failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel strategy for the treatment of congestive heart failure utilizing thyroid hormone signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of innate immunity in genesis of heart failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of the Severity of Acquired von Willebrand Syndrome on the Short-Term Prognosis in Patients with Temporary Mechanical Circulatory Support2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Update of acute and long-term tolvaptan therapy2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Risk Score Efficiently Prevents Tolvaptan-Induced Hypernatremic Events in Patients With Heart Failure2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Tolvaptan Improves Prognosis in Responders with Acute Decompensated Heart Failure by Reducing the Dose of Loop Diuretics2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Effects of Tolvaptan on Volume Overload in Patients with Heart Failure2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Tolvaptan Prolongs Blockage of the Vasopressin Type II Receptor Over 24 Hours in Responders With Stage D Heart Failure2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Tolvaptan Reduces Long-Term Total Medical Expenses and Length of Stay in Aquaporin-Defined Responders2016

Author(s)

Kinugawa Koichiro 絹川弘一郎

絹川弘一郎キヌガワコウイチロウ

KINUGAWA Koh-ichiro 絹川弘一郎