KOBAYASHI Akiko 小林亜紀子

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Kobayashi Akiko 小林亜紀子

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Researcher Number	00345662
Other IDs
Affiliation (Current)	2025: 金沢大学, 総合技術部(医), 技術専門職員
Affiliation (based on the past Project Information) *help	2024: 金沢大学, 総合技術部(医), 技術専門職員 2022 – 2023: 金沢大学, 総合技術部(医), 技術職員 2019 – 2022: 金沢大学, 新学術創成研究機構, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Medium-sized Section 37:Biomolecular chemistry and related fields
Keywords	Principal Investigator mRNA修飾 / NSUN2 / RAE1 / 核膜孔複合体因子 / 子宮内膜がん / ヌクレオポリン / 核膜孔複合体 Except Principal Investigator 相分離 / 翻訳後修飾 / 液－液相分離 / 核膜孔 / 核膜孔複合体

Elucidation of cancer malignant switching mechanism through mRNA modification based on RAE1Principal Investigator
- Principal Investigator
  
  Kobayashi Akiko
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kanazawa University
Functional Dynamics of Liquid-Liquid Phase Separation Mediated by Nuclear Pore Complex
- Principal Investigator
  
  Wong Richard
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kanazawa University
Elucidation of the mechanism of endometrial cancer transformation mediated by nuclear pore complex factorPrincipal Investigator
- Principal Investigator
  
  Kobayashi Akiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kanazawa University

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Spatiotemporal dynamics of protamine-DNA condensation revealed by high-speed atomic force microscopy2025
- Author(s)
  Nishide G, Lim K, Kobayashi A, Qiu Y, Hazawa M, Ando T, Okada Y, Wong RW.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 53 Issue: 6 Pages: 1-11
- DOI
  10.1093/nar/gkaf152
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05939, KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-24K18449
[Journal Article] Optimization of Zwitterionic Polymers for Cell Cryopreservation2024
- Author(s)
  Kato Yui、Uto Takuya、Ishizaki Takeru、Tanaka Daisuke、Ishibashi Kojiro、Matsuda Yuya、Onoda Issei、Kobayashi Akiko、Hazawa Masaharu、Wong Richard W.、Takahashi Kenji、Hirata Eishu、Kuroda Kosuke
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 8 Issue: 7 Pages: 2300499-2300499
- DOI
  10.1002/mabi.202300499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06924, KAKENHI-PLANNED-23H03828
[Journal Article] Cell-compatible isotonic freezing media enabled by thermo-responsive osmolyte-adsorption/exclusion polymer matrices2023
- Author(s)
  Kato Yui、Matsuda Yuya、Uto Takuya、Tanaka Daisuke、Ishibashi Kojiro、Ishizaki Takeru、Ohta Akio、Kobayashi Akiko、Hazawa Masaharu、Wong Richard W.、Ninomiya Kazuaki、Takahashi Kenji、Hirata Eishu、Kuroda Kosuke
- Journal Title
  
  Communications Chemistry
  
  Volume: 6 Issue: 1 Pages: 260-260
- DOI
  10.1038/s42004-023-01061-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06924, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PLANNED-23H03828, KAKENHI-PROJECT-21H03632, KAKENHI-PROJECT-23K23476
[Journal Article] Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.2023
- Author(s)
  Keesiang Lim, Goro Nishide, Elma Sakinatus Sajidah, Tomoyoshi Yamano, Yujia Qiu, Takeshi Yoshida, Akiko Kobayashi, Masaharu Hazawa, Toshio Ando, Rikinari Hanayama, Richard W Wong
- Journal Title
  
  Nano letters
  
  Volume: 23 Issue: 2 Pages: 619-628
- DOI
  10.1021/acs.nanolett.2c04270
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07065, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-22K06924, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K23476
[Journal Article] Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells2023
- Author(s)
  Hazawa M, Ikliptikawati DK, Iwashima Y, Lin DC, Jiang Y, Qiu Y, Makiyama K, Matsumoto K, Kobayashi A, Nishide G, Keesiang L, Yoshino H, Minamoto T, Suzuki T, Kobayashi I, Meguro-Horike M, Jiang YY, Nishiuchi T, Konno H, Koeffler HP, Hosomichi K, Tajima A, Horike SI, Wong RW.
- Journal Title
  
  Cell Chemical Biology
  
  Volume: － Issue: 4 Pages: 792-804.e7
- DOI
  10.1016/j.chembiol.2023.10.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07691, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-22K06880, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-23K27544, KAKENHI-PROJECT-23K27835, KAKENHI-PROJECT-24K18449
[Journal Article] Nanoscopic Elucidation of Spontaneous Self-Assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Open Reading Frame 6 (ORF6) Protein2023
- Author(s)
  Nishide Goro、Lim Keesiang、Tamura Maiki、Kobayashi Akiko、Zhao Qingci、Hazawa Masaharu、Ando Toshio、Nishida Noritaka、Wong Richard W.
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 14 Issue: 38 Pages: 8385-8396
- DOI
  10.1021/acs.jpclett.3c01440
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-20K16262, KAKENHI-PLANNED-21H05250, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K23476
[Journal Article] NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells2022
- Author(s)
  Makiyama Kei、Hazawa Masaharu、Kobayashi Akiko、Lim Keesiang、Voon Dominic C.、Wong Richard W.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 586 Pages: 137-142
- DOI
  10.1016/j.bbrc.2021.11.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K23476
[Journal Article] Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM.2022
- Author(s)
  Elma Sakinatus Sajidah, Keesiang Lim, Tomoyoshi Yamano, Goro Nishide, Yujia Qiu, Takeshi Yoshida, Hanbo Wang, Akiko Kobayashi, Masaharu Hazawa, Firli R P Dewi, Rikinari Hanayama, Toshio Ando, Richard W Wong
- Journal Title
  
  Journal of extracellular vesicles
  
  Volume: 11 Issue: 11 Pages: 12275-12275
- DOI
  10.1002/jev2.12275
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07065, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K23476
[Journal Article] Inhibition of Canonical Wnt Signaling Promotes Ex Vivo Maintenance and Proliferation of Hematopoietic Stem Cells in Zebrafish2022
- Author(s)
  Kimura Koki、Yamamori Shiori、Hazawa Masaharu、Kobayashi-Sun Jingjing、Kondo Mao、Wong Richard W、Kobayashi Isao
- Journal Title
  
  Stem Cells
  
  Volume: 40 Issue: 9 Pages: 831-842
- DOI
  10.1093/stmcls/sxac044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-22KJ2574
[Journal Article] Discovery of a Novel Aminocyclopropenone Compound That Inhibits BRD4-Driven Nucleoporin NUP210 Expression and Attenuates Colorectal Cancer Growth2022
- Author(s)
  Kondo Hiroya、Mishiro Kenji、Iwashima Yuki、Qiu Yujia、Kobayashi Akiko、Lim Keesiang、Domoto Takahiro、Minamoto Toshinari、Ogawa Kazuma、Kunishima Munetaka、Hazawa Masaharu、Wong Richard W.
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 3 Pages: 317-317
- DOI
  10.3390/cells11030317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-20K15953, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K24403, KAKENHI-PROJECT-23K23476
[Journal Article] A light-switching pyrene probe to detect phase-separated biomolecules2021
- Author(s)
  Hazawa Masaharu、Amemori Shogo、Nishiyama Yoshio、Iga Yoshihiro、Iwashima Yuki、Kobayashi Akiko、Nagatani Hirohisa、Mizuno Motohiro、Takahashi Kenji、Wong Richard W.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 8 Pages: 102865-102865
- DOI
  10.1016/j.isci.2021.102865
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05521, KAKENHI-PROJECT-19K07398, KAKENHI-PUBLICLY-19H04674, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-21K19043
[Journal Article] High-Speed Atomic Force Microscopy Reveals Spatiotemporal Dynamics of Histone Protein H2A Involution by DNA Inchworming2021
- Author(s)
  Nishide Goro、Lim Keesiang、Mohamed Mahmoud Shaaban、Kobayashi Akiko、Hazawa Masaharu、Watanabe-Nakayama Takahiro、Kodera Noriyuki、Ando Toshio、Wong Richard W.
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 12 Issue: 15 Pages: 3837-3846
- DOI
  10.1021/acs.jpclett.1c00697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-19K07398, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262
[Journal Article] Synthetic zwitterions as efficient non-permeable cryoprotectants2021
- Author(s)
  Kato Yui、Uto Takuya、Tanaka Daisuke、Ishibashi Kojiro、Kobayashi Akiko、Hazawa Masaharu、Wong Richard W.、Ninomiya Kazuaki、Takahashi Kenji、Hirata Eishu、Kuroda Kosuke
- Journal Title
  
  Communications Chemistry
  
  Volume: 4 Issue: 1 Pages: 151-151
- DOI
  10.1038/s42004-021-00588-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-20H03510, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K15232
[Journal Article] Millisecond dynamic of SARS‐CoV‐2 spike and its interaction with ACE2 receptor and small extracellular vesicles2021
- Author(s)
  Lim Keesiang、Nishide Goro、Yoshida Takeshi、Watanabe‐Nakayama Takahiro、Kobayashi Akiko、Hazawa Masaharu、Hanayama Rikinari、Ando Toshio、Wong Richard W.
- Journal Title
  
  Journal of Extracellular Vesicles
  
  Volume: 10 Issue: 14
- DOI
  10.1002/jev2.12170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262
[Journal Article] Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex2021
- Author(s)
  Kato Koki、Ikliptikawati Dini Kurnia、Kobayashi Akiko、Kondo Hiroya、Lim Keesiang、Hazawa Masaharu、Wong Richard W.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 536 Pages: 59-66
- DOI
  10.1016/j.bbrc.2020.11.115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20K07568
[Journal Article] Label-free tomographic imaging of nanodiamonds in living cells2021
- Author(s)
  Ikliptikawati Dini Kurnia、Hazawa Masaharu、So Frederick T.-K.、Terada Daiki、Kobayashi Akiko、Segawa Takuya F.、Shirakawa Masahiro、Wong Richard W.
- Journal Title
  
  Diamond and Related Materials
  
  Volume: 118 Pages: 108517-108517
- DOI
  10.1016/j.diamond.2021.108517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20H00453, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-21K19043
[Journal Article] Nucleoporin TPR (translocated promoter region, nulear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma.2020
- Author(s)
  Dewi FRP, Jiapear S, Kobayashi A, Hazawa M, Ikliptikawati DK, Hartono, Sabit H, Nakada M, Wong RW
- Journal Title
  
  Autophagy
  
  Volume: 24 Issue: 4 Pages: 1-12
- DOI
  10.1080/15548627.2020.1741318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-17K08655, KAKENHI-PROJECT-18H02910
[Journal Article] Spatiotemporally tracking of nano-biofilaments inside the nuclear pore complex core2020
- Author(s)
  Mohamed Mahmoud Shaaban、Hazawa Masaharu、Kobayashi Akiko、Guillaud Laurent、Watanabe-Nakayama Takahiro、Nakayama Mizuho、Wang Hanbo、Kodera Noriyuki、Oshima Masanobu、Ando Toshio、Wong Richard W.
- Journal Title
  
  Biomaterials
  
  Volume: 256 Pages: 120198-120198
- DOI
  10.1016/j.biomaterials.2020.120198
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06494, KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20K07568, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-20H00327
[Journal Article] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Lim Keesiang、Kodera Noriyuki、Wang Hanbo、Mohamed Mahmoud Shaaban、Hazawa Masaharu、Kobayashi Akiko、Yoshida Takeshi、Hanayama Rikinari、Yano Seiji、Ando Toshio、Wong Richard W.
- Journal Title
  
  Nano Letters
  
  Volume: 20 Issue: 9 Pages: 6320-6328
- DOI
  10.1021/acs.nanolett.0c01755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20K07568, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-20K16262, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-19K23841
[Journal Article] Nucleoporin Nup58 Localizes to centrosomes and mid-bodies during mitosis.2019
- Author(s)
  Hartono, Hazawa M, Lim KS, Dewi FRP, Kobayashi A, Wong RW
- Journal Title
  
  Cell Division
  
  Volume: 14 Issue: 1
- DOI
  10.1186/s13008-019-0050-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-17K08655
[Journal Article] Direct Visualization of Avian Influenza H5N1 Hemagglutinin Precursor and its Conformational Change by High-Speed Atomic Force Microscopy2019
- Author(s)
  Lim SK, Mohamed MS, Wang H, Hartono, Hazawa M, Kobayashi A, Voon DC, Kodera N, Ando T and Wong RW
- Journal Title
  
  BBA - General Subjects
  
  Volume: 印刷中 Issue: 2 Pages: 129313-129313
- DOI
  10.1016/j.bbagen.2019.02.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08655, KAKENHI-PROJECT-17K16332, KAKENHI-PUBLICLY-17H05874, KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-19K07398, KAKENHI-WRAPUP-19H05452, KAKENHI-PROJECT-17K19345
[Journal Article] Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma2019
- Author(s)
  Hazawa Masaharu、Sakai Kie、Kobayashi Akiko、Yoshino Hironori、Iga Yoshihiro、Iwashima Yuki、Lim Kee Sing、Chih-Cheng Voon Dominic、Jiang Yan-Yi、Horike Shin-ichi、Lin De-Chen、Wong Richard W.
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 10 Pages: 2212-2223
- DOI
  10.1038/s41388-019-1137-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623, KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-17K08655, KAKENHI-PROJECT-17K16332
[Presentation] 高速AFMによるプロタミン-DNA凝集ダイナミクスの解明2024
- Author(s)
  西出梧朗, Keesiang Lim, 小林亜紀子, Yujia Qiu, 羽澤勝治, 岡田由紀, 西田紀貴, Richard Wong
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] Characterization of full-length SARS-CoV-2 Open Reading Frame 6 (ORF6) protein's molecular properties through HS-AFM analysis2024
- Author(s)
  西出梧朗, Keesiang Lim, 田村真生, 小林亜紀子, 趙慶慈, 羽澤勝治, 安藤敏夫, 西田紀貴, Richard Wong
- Organizer
  第24回日本蛋白質科学回年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] Native molecular properties of full-length SARS-CoV-2 Open Reading Frame 6 (ORF6) protein observed using HS-AFM2024
- Author(s)
  Goro Nishide, Keesiang Lim，Maiki Tamura，Akiko Kobayashi，Qingci Zhao，Masaharu Hazawa，Toshio Ando，Noritaka Nishida，Richard W. Wong
- Organizer
  21st IUPAB Congress 2024 (IUPAB2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] High speed-AFM reveals the millisecond dynamic of small extracellular vesicle nanotopology in response to physicochemical stresses.2023
- Author(s)
  Elma Sakinatus Sajidah, Keesiang Lim, Tomoyoshi Yamano, Goro Nishide, Qiu Yujia, Takeshi Yoshida, Akiko Kobayashi, Masaharu Hazawa, Rikinari Hanayama, Toshio Ando, Richard Wong
- Organizer
  ISEV2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] High speed-AFM as a nanoscopic tool for anti-SARS-CoV-2 spike neutralizaing antibody assessment.2023
- Author(s)
  Keesiang Lim, Goro Nishide, Elma Sakinatus Sajidah, Tomoyoshi Yamano, Qiu Yujia, Takeshi Yoshida, Akiko Kobayashi, Masaharu Hazawa, Toshio Ando, Rikinari Hanayama, Richard Wong.
- Organizer
  ISEV2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] Milisecond dynamics of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM2022
- Author(s)
  Sajidah Elma Sakinatus, Lim Keesiang, Yamano Tomoyoshi, Yoshida Takeshi, Kobayashi Akiko, Hazawa Masaharu, Inaba Yuka, Inoue Hiroshi, Hanayama Rikinari, Ando Toshio, Wong Richard W
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] SARS-CoV-2 由来タンパク質 ORF6は RAE1 と NUP98 の局在変化を引き起こす2022
- Author(s)
  加藤弘毅、Dini Kurnia Ikliptikawati、小林亜紀子、他３名Kee Siang Lim、羽澤勝治、Richard Wong
- Organizer
  第 82 回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-22K06924
[Presentation] SARS-CoV-2由来ORF6は核膜孔複合体 RAE1とNUP98の局在変化を引き起こす2021
- Author(s)
  加藤弘毅、小林亜紀子、羽澤勝治、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] The epigenetic role of nucleoporin RAE1 in human breast cancer2021
- Author(s)
  Dini Kurnia Ikliptikawati, Akiko Kobayashi, Masaharu Hazawa, Richard W.Wong
- Organizer
  The 39th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] SARS-CoV-2由来ORF6は核膜孔複合体RAE1とNUP98の局在変化を引き起こす2021
- Author(s)
  加藤弘毅、小林亜紀子、羽澤勝治、Richard W Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速 AFM を用いた DNA インチワーミングによるヒストン H2A ラッピング動態の実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速 AFM によるヒストン H2A トポグラフィーとその DNA コンパクション時の時空間ダイナミクスの解明2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 液-液相分離の動態解析を可能とする機能性蛍光プローブ2021
- Author(s)
  羽澤勝治、雨森翔悟、西山嘉男、岩嶋友紀、小林亜紀子、永谷　広久、水野元博、髙橋憲司、ウォングリチャード
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] Investigation of real-time dynamic histone H2A-DNA interaction and H2A-DNA condensation/de-condensation using high-speed AFM2021
- Author(s)
  西出梧朗、Keesiang LIM、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard WONG
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 核膜孔複合体による核膜近傍での転写制御機構2021
- Author(s)
  岩嶋友紀、羽澤勝治、Qiu Yujia、Dini Kurnia Ikliptikawati、西出梧朗、小林亜紀子、Lim Kee Siang、Richard Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 新規アミノシクロプロペノン化合物は BRD4 依存的 NUP210 の発現を阻害し、がん細胞の増殖を抑制する2021
- Author(s)
  近藤寛弥、三代憲司、羽澤勝治、岩嶋友紀、小林亜紀子、小川数馬、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 核膜孔複合体による転写制御機構2021
- Author(s)
  岩嶋友紀、羽澤勝治、Qiu Yujia、Dini Kurnia Ikliptikawati1、西出梧朗、小林亜紀子、Lim Kee Siang、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 高速 AFM によるヒストン H2A トポグラフィーとその DNA コンパクション時の時空間ダイナミクスの解明2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 核内相分離の制御を可能とする新規アミノシクロプロペノン化合物の発見2021
- Author(s)
  近藤寛弥、三代憲司、岩嶋友紀、Qiu Yujia、稲葉有香、小林亜紀子、Keesiang Lim、源利成、小川数馬、國嶋崇隆、羽澤勝治、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速AFMを用いたヒストンH2A-DNA実時空間イメージングによるヌクレオソーム凝縮プロセスとその環境の解明2021
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] SARS-CoV-2由来ORF6は核膜孔複合体 RAE1とNUP98の局在変化を引き起こす2021
- Author(s)
  加藤弘毅、小林亜紀子、羽澤勝治、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 液-液相分離の動態解析を可能とする機能性蛍光プローブ2021
- Author(s)
  羽澤勝治、雨森翔悟、西山嘉男、岩嶋友紀、小林亜紀子、永谷　広久、水野元博、髙橋憲司、ウォングリチャード
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 上衣腫における核膜孔複合体タンパク質Tprの役割2021
- Author(s)
  小林亜紀子、Shabierjiang Jiapaer、Firli R.P. Dewi、羽澤勝治、Dini K. Ikliptikawati、Hartono、Hemragul Sabit、中田光俊、Richard Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 核膜孔複合体による転写制御機構2021
- Author(s)
  岩嶋友紀、羽澤勝治、Qiu Yujia、Dini Kurnia Ikliptikawati1、西出梧朗、小林亜紀子、Lim Kee Siang、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] ヒストンH2A-DNAダイナミクスの実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、稲葉有香、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速 AFM を用いた DNA インチワーミングによるヒストン H2A ラッピング動態の実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 新規アミノシクロプロペノン化合物は BRD4 依存的 NUP210 の発現を阻害し、がん細胞の増殖を抑制する2021
- Author(s)
  近藤寛弥、三代憲司、羽澤勝治、岩嶋友紀、小林亜紀子、小川数馬、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] Investigation of real-time dynamic histone H2A-DNA interaction and H2A-DNA condensation/de-condensation using high-speed AFM2021
- Author(s)
  西出梧朗、Keesiang LIM、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard WONG
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 新規アミノシクロプロぺノン化合物はBRD4依存的なNUP210の発現を阻害し、がん細胞の増殖を抑制する2021
- Author(s)
  近藤寛弥、三代憲司、羽澤勝治、岩嶋友紀、小林亜紀子、小川数馬、Richard Wong
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] Molecular Dynamic of Coronavirus Spike Protein2021
- Author(s)
  Keesiang Lim, Goro Nishide, Takeshi Yoshida, Takahiro Watanabe-Nakayama, Akiko Kobayashi, Masaharu Hazawa, Rikinari Hanayama, Toshio Ando, Richard W. Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] The epigenetic role of nucleoporin RAE1 in human breast cancer2021
- Author(s)
  Dini Kurnia Ikliptikawati, Akiko Kobayashi, Masaharu Hazawa, Richard W.Wong
- Organizer
  The 39th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 核内相分離の制御を可能とする新規アミノシクロプロペノン化合物の発見2021
- Author(s)
  近藤寛弥、三代憲司、岩嶋友紀、Qiu Yujia、稲葉有香、小林亜紀子、Keesiang Lim、源利成、小川数馬、國嶋崇隆、羽澤勝治、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 高速 AFM を用いた DNA インチワーミングによるヒストン H2A ラッピング動態の実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 高速AFMを用いたヒストンH2A-DNA実時空間イメージングによるヌクレオソーム凝縮プロセスとその環境の解明2021
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 新規アミノシクロプロぺノン化合物はBRD4依存的なNUP210の発現を阻害し、がん細胞の増殖を抑制する2021
- Author(s)
  近藤寛弥、三代憲司、羽澤勝治、岩嶋友紀、小林亜紀子、小川数馬、Richard Wong
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] SARS-CoV-2由来ORF6は核膜孔複合体RAE1とNUP98の局在変化を引き起こす2021
- Author(s)
  加藤弘毅、小林亜紀子、羽澤勝治、Richard W Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] Molecular Dynamic of Coronavirus Spike Protein2021
- Author(s)
  Keesiang Lim, Goro Nishide, Takeshi Yoshida, Takahiro Watanabe-Nakayama, Akiko Kobayashi, Masaharu Hazawa, Rikinari Hanayama, Toshio Ando, Richard W. Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 上衣腫における核膜孔複合体タンパク質Tprの役割2021
- Author(s)
  小林亜紀子、Shabierjiang Jiapaer、Firli R.P. Dewi、羽澤勝治、Dini K. Ikliptikawati、Hartono、Hemragul Sabit、中田光俊、Richard Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 高速 AFM を用いた DNA インチワーミングによるヒストン H2A ラッピング動態の実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] ヒストンH2A-DNAダイナミクスの実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、稲葉有香、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] Elucidation of histone H2A topography and its nanomechanics with DNA compaction using high-speed atomic force microscopy2020
- Author(s)
  西出梧朗, Keesiang Lim, Mahmoud Shaaban Mohamed, 小林亜紀子, 羽澤勝治, Hanbo Wang, 中山隆宏, 古寺哲幸, 安藤敏夫, Richard Wong
- Organizer
  第43回日本分子生物学会年会（オンライン）
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 高速原子間力顕微鏡によるヒストンH2A動態の実時空間イメージング2020
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、羽澤勝治、小林亜紀子、Richard Wong
- Organizer
  第７２回日本細胞生物学会大会（京都、オンライン）
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] NUP210ががん細胞の核サイズと増殖能力を調節する2020
- Author(s)
  近藤寛弥、三代憲治、羽澤勝治、小林亜紀子、Richard Wong
- Organizer
  第７２回日本細胞生物学会大会（京都、オンライン）
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Keesiang Lim, Noriyuki Kodera, Hanbo Wang, Mahmoud Shaaban Mohamed, Masaharu Hazawa, Akiko Kobayashi, Takeshi Yoshida, Rikinari Hanayama, Seiji Yano, Toshio Ando, Richard Wong
- Organizer
  NanoLSI Symposium (4th) (Kanazawa)
- Data Source
  KAKENHI-PROJECT-19K07398
[Presentation] 上衣腫における核膜孔複合体因子TPRの役割について2020
- Author(s)
  小林亜紀子、Dewi Firli、Jiapaer Shabierjiang、羽澤勝治、Ikliptikawati Dini、Sabit Hemragul、中田光俊、Richard Wong
- Organizer
  第７２回日本細胞生物学会大会（京都、オンライン）
- Data Source
  KAKENHI-PROJECT-19K07398

1. Wong Richard (30464035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
2. 羽澤勝治 (40622460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
3. LIM KEE・SIANG (60842987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. OKADA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 西山嘉男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 山野友義

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 安藤敏夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Guillaud Laurent

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 吉野浩教

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KOBAYASHI Akiko 小林 亜紀子

Kobayashi Akiko 小林 亜紀子

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Co-Researchers

Elucidation of cancer malignant switching mechanism through mRNA modification based on RAE1Principal Investigator

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Functional Dynamics of Liquid-Liquid Phase Separation Mediated by Nuclear Pore Complex

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Elucidation of the mechanism of endometrial cancer transformation mediated by nuclear pore complex factorPrincipal Investigator

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[Journal Article] Spatiotemporal dynamics of protamine-DNA condensation revealed by high-speed atomic force microscopy2025

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[Journal Article] Optimization of Zwitterionic Polymers for Cell Cryopreservation2024

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[Journal Article] Cell-compatible isotonic freezing media enabled by thermo-responsive osmolyte-adsorption/exclusion polymer matrices2023

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[Journal Article] Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.2023

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[Journal Article] Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells2023

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[Journal Article] Nanoscopic Elucidation of Spontaneous Self-Assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Open Reading Frame 6 (ORF6) Protein2023

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[Journal Article] NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells2022

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[Journal Article] Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM.2022

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[Journal Article] Inhibition of Canonical Wnt Signaling Promotes Ex Vivo Maintenance and Proliferation of Hematopoietic Stem Cells in Zebrafish2022

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[Journal Article] Discovery of a Novel Aminocyclopropenone Compound That Inhibits BRD4-Driven Nucleoporin NUP210 Expression and Attenuates Colorectal Cancer Growth2022

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[Journal Article] A light-switching pyrene probe to detect phase-separated biomolecules2021

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[Journal Article] High-Speed Atomic Force Microscopy Reveals Spatiotemporal Dynamics of Histone Protein H2A Involution by DNA Inchworming2021

Author(s)

KOBAYASHI Akiko 小林亜紀子

Kobayashi Akiko 小林亜紀子