Sakamoto Yasumitsu 阪本泰光

… Alternative Names

SAKAMOTO YASUMITSU 阪本泰光

SAKAMOTO Yasumitsu 阪本泰光

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Researcher Number	00349036
Other IDs	https://orcid.org/0000-0003-1067-954X
Affiliation (Current)	2025: 岩手医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 岩手医科大学, 薬学部, 教授 2017 – 2022: 岩手医科大学, 薬学部, 准教授 2013 – 2016: 岩手医科大学, 薬学部, 助教 2008: Iwate Medical University, 薬学部, 助手 2007: Showa University, 保健医療学部, 講師 2006: 昭和大学, 保健医療学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 43030:Functional biochemistry-related / Drug development chemistry / Morphological basic dentistry / Structural biochemistry Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Basic Section 57020:Oral pathobiological science-related
Keywords	Principal Investigator DPP / 抗菌薬 / 多剤耐性 / 構造生物 / SBDD / AMR / 歯周病 / 結晶構造解析 / S46 / 蛋白質 … More / 構造生物学 / 創薬 / プロテアーゼ / 微小重力 / 糖悲発酵 / NFGNB / 薬剤耐性 / 感染症 / 酵素 / 糖非発酵グラム陰性桿菌 / FE創薬 / ジペプチジルアミノペプチダーゼ / 多発性骨髄腫 / グラム陰性 / 糖非発酵 / 歯周病菌 / 多剤耐性菌 / NFGNR / S46 peptidase / Perio / Antibiotics / ペプチダーゼ / DPP11 / プロテオーム / 脳・神経 / 脳 / タンパク質 / 生体分子 / X線結晶構造解析 / CNPase … More Except Principal Investigator P. gingivalis / ジペプチジルペプチダーゼ / 糖尿病 / 歯周病 / ロイコトキシン / ワクチン / LFA-1 / LtxA / A. actinomycetemcomitans / 侵襲性歯周炎 Less

糖非発酵グラム陰性細菌のペプチド代謝機構を標的とした抗菌薬開発Principal Investigator
- Principal Investigator
  
  阪本泰光
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Iwate Medical University
選択的ジペプチジルペプチダーゼ阻害剤による糖尿病関連歯周炎に対する創薬研究
- Principal Investigator
  
  野中由香莉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Drug discovery research targeting the mechanism of peptide metabolism in sugar non-fermenting Gram-negative bacteriaPrincipal Investigator
- Principal Investigator
  
  Sakamoto Yasumitsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Iwate Medical University
Elucidation of the molecular basis of leukotoxin-receptor interactions and development of a novel periodontitis vaccine.
- Principal Investigator
  
  Yoshida Akihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Matsumoto Dental University
Molecular basis for drug discovery of dipeptidyl amino peptidases from Non-Fermented Gram-Negative RodsPrincipal Investigator
- Principal Investigator
  
  Sakamoto Yasumitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Iwate Medical University
Structural and functional studies of dipeptidyl aminopeptidases from periodontal pathogen.Principal Investigator
- Principal Investigator
  
  SAKAMOTO YASUMITSU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Iwate Medical University
Crystal structure of 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, CNPase from human brainPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Yasumitsu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Iwate Medical University
  Showa University

All 2019 2018 2017 2016 2015 2014 2009 2008 2007 2006

All Journal Article Presentation Book Patent

[Book] 看護学学習辞典2008
- Author(s)
  相川直樹,大橋優美子,菅原スミ,吉野肇一,阪本泰光他
- Total Pages
  1698
- Publisher
  学習研究社
- Data Source
  KAKENHI-PROJECT-18770096
[Book] 看護学学習辞典2008
- Author(s)
  相川直樹、大橋優美子, 菅原スミ, 吉野肇一、阪本泰光, 他
- Total Pages
  1732
- Publisher
  学習研究社
- Data Source
  KAKENHI-PROJECT-18770096
[Journal Article] The Crystal Structure of Peptidase Toward Drug Discovery2019
- Author(s)
  阪本泰光、六本木沙織、鈴木義之、石原司、日高興士、中村彰宏、本間宣行、小笠原渉、田中信忠
- Journal Title
  
  International journal of microgravity science and application
  
  Volume: 36 Issue: 1 Pages: 360106
- DOI
  10.15011//jasma.36.360106
- NAID
  130007842629
- ISSN
  2188-9783
- Year and Date
  2019-01-31
- Language
  Japanese
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-16K08322
[Journal Article] Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues2018
- Author(s)
  Roppongi Saori、Suzuki Yoshiyuki、Tateoka Chika、Fujimoto Mayu、Morisawa Saori、Iizuka Ippei、Nakamura Akihiro、Honma Nobuyuki、Shida Yosuke、Ogasawara Wataru、Tanaka Nobutada、Sakamoto Yasumitsu、Nonaka Takamasa
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2714-2714
- DOI
  10.1038/s41598-018-21056-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04902, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-15K14231, KAKENHI-PROJECT-16K08322
[Journal Article] Periplasmic form of dipeptidyl aminopeptidase IV from Pseudoxanthomonas mexicana WO24: purification, kinetic characterization, crystallization and X‐ray crystallographic analysis2017
- Author(s)
  Saori Roppongi Chika Tateoka Mayu Fujimoto Ippei Iizuka Saori Morisawa Akihiro Nakamura Nobuyuki Honma Yoshiyuki Suzuki Yosuke Shida Wataru Ogasawara Nobutada Tanaka Yasumitsu Sakamoto Takamasa Nonaka
- Journal Title
  
  Acta Crystallographica Section F
  
  Volume: 73 Issue: 11 Pages: 501-606
- DOI
  10.1107/s2053230x17014911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04902, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-15K14231, KAKENHI-PROJECT-16K08322
[Journal Article] Structural and Functional Studies of Dipeptidyl Aminopeptidase from Non-Fermenting Gram-Negative Rods2016
- Author(s)
  阪本泰光、野中孝昌、鈴木義之、小笠原渉、田中信忠
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 58 Issue: 5 Pages: 221-227
- DOI
  10.5940/jcrsj.58.221
- NAID
  130005267922
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08322
[Journal Article] Crystal Structure of Dipeptidyl Peptidase 11 from Porphyromonas gingivalis: the Molecular Basis of Substrate Specificity among the Family S46 Peptidases2016
- Author(s)
  Sakamoto Y, Tanaka N
- Journal Title
  
  Photon Factory Highlights
  
  Volume: 2015 Pages: 56-57
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08322
[Journal Article] Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity.2015
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Yamada M, Ohta K, Gouda H, Nonaka T, Ogasawara W, Tanaka N.
- Journal Title
  
  Scientific Reports
  
  Volume: 87 Issue: 1 Pages: 11151-11151
- DOI
  10.1038/srep11151
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis.2015
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Gouda H, Nonaka T, Ogasawara W, Tanaka N.
- Journal Title
  
  Acta Crystallogr F Struct Biol Commun.
  
  Volume: 71 Issue: 2 Pages: 206-210
- DOI
  10.1107/s2053230x15000424
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] Structures and functions of novel exopeptideses involved in peptide metabolism2015
- Author(s)
  Sakamoto Y, Nonaka T
- Journal Title
  
  生化学
  
  Volume: 87 Issue: 6 Pages: 762-765
- DOI
  10.14952/SEIKAGAKU.2015.870762
- NAID
  40020687497
- ISSN
  0037-1017
- Year and Date
  2015-12-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of dipeptidyl aminopeptidase BII from {\it Pseudoxanthomonas mexicana} WO242014
- Author(s)
  Sakamoto, Y.
- Journal Title
  
  Acta Cryst. F
  
  Volume: 70 Issue: 2 Pages: 221-221
- DOI
  10.1107/s2053230x13034584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] S46 peptidases are the first exopeptidases to be members of clan PA.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 4977-4977
- DOI
  10.1038/srep04977
- NAID
  120006832415
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] Structural comparison analysis of 2H phosphodiesterase family proteins.2008
- Author(s)
  Sakamoto, Y・Tanaka, N・Ichimiya, T・Kurihara, T・Nakamura, KT.
- Journal Title
  
  Nucleic Acids Symposium Series 51
  
  Pages: 447-448
- Data Source
  KAKENHI-PROJECT-18770096
[Journal Article] Structural comparison analysis of 2H phosphodiesterase family proteins2007
- Author(s)
  Sakamoto Y, Tanaka N, Ichimiya T, Kurihara T, Nakamura T.K
- Journal Title
  
  Nucleic Acids Symp. Ser 51
  
  Pages: 447-448
- Data Source
  KAKENHI-PROJECT-18770096
[Journal Article] Crystal structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum complexed with a selective inhibitor2006
- Author(s)
  Tanaka N, Kusakabe Y, Aoki K, Sakamoto Y, Tsunoda M, Kitagawa Y, Nakamura T.K
- Journal Title
  
  Photon Factory Activity Report 24
  
  Pages: 216-216
- Data Source
  KAKENHI-PROJECT-18770096
[Journal Article] Crystal Structures of Mouse Autocrine Motility Factor Complexed with Various Carbohydrate Phosphate2006
- Author(s)
  Tanaka N, Naba N, Shiraiwa K, Kusakabe Y,Aoki K, Tsunoda M, Sakamoto Y, M, Kitagawa Y, Nakamura T.K
- Journal Title
  
  Photon Factory Activity Report 23
  
  Pages: 195-195
- Data Source
  KAKENHI-PROJECT-18770096
[Patent] 細菌由来ジペプチジルペプチダーゼの酵素活性を阻害するジペプチド誘導体2017
- Inventor(s)
  阪本泰光、日高興士、津田裕子、小笠原渉
- Industrial Property Rights Holder
  阪本泰光、日高興士、津田裕子、小笠原渉
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-156345
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] クスリ創りの新時代へ　～宇宙実験・アカデミア創薬・ロボット創薬のコラボレーションによる新薬創製への挑戦～2019
- Author(s)
  阪本泰光, 田中信忠, 石原司
- Organizer
  「きぼう」利用シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 「Stenotrophomonas maltophilia 由来 Dipeptidyl peptidase 7 の基質 P2 認識機構の解析」2019
- Author(s)
  中村彰宏、橋口太一、本間宣行、鈴木義之、阪本泰光、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] ジペプチジルアミノペプチダーゼ 4 ファミリーの立体構造比較研究2019
- Author(s)
  六本木沙織、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 宇宙を新薬設計に役立てる -基礎研究から民間利用への拡がり」2019
- Author(s)
  西島和三、舛屋圭一、細田雅人、阪本泰光、善光龍哉
- Organizer
  「きぼう」利用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Elucidation of substrate recognition mechanism of dipeptidyl aminopeptidase IV from Gram-negative bacteria2019
- Author(s)
  Akihiro Nakamura, Nobuyuki Honma, Saori Roppongi, Yoshiyuki Suzuki, Yosuke Shida, Yasumitsu Sakamoto, Koji Inaka, Hiroaki Tanaka, Kiyoito Kihira, Mitsugu Yamada, Izumi Yoshioka, Hiroaki Gouda, Takamasa Nonaka, Nobutada Tanaka, Wataru Ogasawara
- Organizer
  7th International GIGAKU conference in Nagaoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Pseudoxanthomonas mexicana WO24由来Dipeptidyl aminopeptidase IVの基質認識機構の解明2018
- Author(s)
  中村彰宏、本間宣行、六本木沙織、鈴木義之、志田洋介、阪本泰光、飯塚一平、伊中浩治、田仲広明、木平清人、山田貢、吉崎泉、合田浩明、野中孝昌、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] X線結晶構造に基づく多剤耐性菌由来DPP-7阻害剤の設計と評価2018
- Author(s)
  関拓海、奥野優香、櫻井有紀、日高興士、宮崎杏奈、北條恵子、六本木沙織、阪本泰光、伊藤康広、鈴木義之、小笠原渉、田中信忠、木平清人、山田貢、吉崎泉、田仲広明、伊中浩治、津田裕子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Pseudoxanthomonas mexicana WO24由来Dipeptidyl aminopeptidase IVの構造・機能解析2018
- Author(s)
  中村彰宏、本間宣行、六本木沙織、鈴木義之、志田洋介、阪本泰光、飯塚一平、伊中浩治、田仲広明、木平清人、山田貢、吉崎泉、合田浩明、野中孝昌、田中信忠、小笠原渉
- Organizer
  第12回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 微生物ジペプチジルアミノペプチダーゼIVの結晶構造解析2018
- Author(s)
  六本木沙織※、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 微生物Dipeptidyl aminopeptidase IVの結晶構造解析2018
- Author(s)
  六本木沙織、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  2017年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 岩手と宇宙で拓く　アカデミア創薬の取り組み」2018
- Author(s)
  阪本泰光
- Organizer
  盛岡経済研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 微生物ジペプチジルアミノペプチダーゼIVの結晶構造解析2018
- Author(s)
  六本木沙織、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 部位特異的変異導入解析によるFamily S46ペプチダーゼの基質認識残基の同定2018
- Author(s)
  本間宣行、中村彰宏、六本木沙織、鈴木義之、志田洋介、阪本泰光、飯塚一平、伊中浩治、田仲広明、木平清人、山田貢、吉崎泉、合田浩明、野中孝昌、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Identification for Substrate Recognition Residues in Family S46 Peptidase from Pathogenic Non-Fermenting Gram-Negative Bacteria2017
- Author(s)
  Akihiro Nakamura、Yasuhiro Ito、Yoshiyuki Suzuki、Saori Roppongi、Koshi Hidaka、Yasumitsu Sakamoto、Nobutada Tanaka and Wataru Ogasawara
- Organizer
  International Union of Microbiogical Societies (IUMS) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] PFでの結晶化スクリーニングとプレートスクリーニングの現状2017
- Author(s)
  阪本泰光
- Organizer
  第2回PFユーザーグループ主催講習会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Identification of dipeptidic inhibitors targeting DPP7 derived from resistant multidrug resistant bacterium Stenotrophomonas maltophilia2017
- Author(s)
  Yuki Sakurai、Koushi Hidaka、Anna Miyazaki、Keiko Hojo、Saori Roppongi、Yasumitsu Sakamoto、Yasuhiro Ito、Yoshiyuki Suzuki、Wataru Ogasawara、Nobutada Tanaka、and Yuko Tsuda
- Organizer
  第54回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] S46 Family bacterial dipeptidyl aminopeptidases as novel antibiotics targets.2017
- Author(s)
  Yasumitsu Sakamoto、Yoshiyuki Suzuki、Ippei Iizuka、Chika Tateoka、Saori Roppongi、Mayu Fujimoto、Yasuhiro Ito、Koji Inaka、Hiroaki Tanaka、Mitsugu Yamada、Kazunori Ohta、Hiroaki Gouda、Takamasa
- Organizer
  International Union of Microbiogical Societies (IUMS) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 宇宙実験での最近の成果2017
- Author(s)
  阪本泰光
- Organizer
  iBIX-JAXA合同タンパク質研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 糖非発酵グラム陰性細菌由来ペプチド分解酵素の結晶構造解析2017
- Author(s)
  ◯六本木沙織、館岡千佳、鈴木義之、伊藤康弘、藤本真友、森澤さおり、飯塚一平、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Family S46 ペプチダーゼの新規基質認識残基の同定2017
- Author(s)
  中村彰宏、伊藤康広、鈴木義之、六本木沙織、飯塚一平、阪本泰光、田中信忠、小笠原渉Family S46 ペプチダーゼの新規基質認識残基の同定
- Organizer
  第17回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Crystal structures of dipeptidyl aminopeptidase IV from non-fermenting gram negative Rods.2017
- Author(s)
  Saori Roppongi、Chika Tateoka、Mayu Fujimoto、Ippei Iizuka、Saori Morisawa、Akihiro Nakamura、Nobuyuki Honma、Yasuhiro Ito、Yoshiyuki Suzuki、Wataru Ogasawara、Nobutada Tanaka、Yasumitsu Sakamoto、Takamasa Nonaka
- Organizer
  International Union of Microbiogical Societies (IUMS) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 糖非発酵グラム陰性細菌由来ジペプチジルアミノペプチダーゼ4の結晶構造解析2017
- Author(s)
  ◯六本木沙織、館岡千佳、鈴木義之、伊藤康弘、藤本真友、森澤さおり、飯塚一平、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  2016年度量子ビームサイエンスフェスタ
- Place of Presentation
  つくば
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Analysis of Substrate Recognition Residues in Family S46 Peptidase from Gram-Negative Bacteria2017
- Author(s)
  Akihiro Nakamura、Yasuhiro Ito、Yoshiyuki Suzuki、Saori Roppongi、Koshi Hidaka、Yasumitsu Sakamoto、Nobutada Tanaka and Wataru Ogasawara
- Organizer
  6th International GIGAKU conference in Nagaoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 歯周病菌由来酸性アミノ酸特異的DPP（ジペプチジルペプチダーゼ）の構造生物学的研究（2016
- Author(s)
  六本木沙織、鈴木義之、飯塚一平、舘岡千佳、藤本真友、伊中浩治、田仲広明、太田和敬、山田貢、合田浩明、野中孝昌、小笠原渉、田中信忠、阪本泰光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] 糖非発酵グラム陰性細菌由来ペプチド分解酵素の構造生物学的研究2016
- Author(s)
  ◯六本木沙織、館岡千佳、鈴木義之、藤本真友、森澤さおり、飯塚一平、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  第55回日本薬学会東北支部大会
- Place of Presentation
  郡山
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 歯周病菌由来DPP11の構造生物学的研究2016
- Author(s)
  六本木沙織、鈴木義之、飯塚一平、伊中浩治、田仲広明、太田和敬、山田貢、小笠原渉、田中信忠、野中孝昌、阪本泰光
- Organizer
  2015 量子ビームサイエンスフェスタ
- Place of Presentation
  つくば市
- Year and Date
  2016-03-15
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal structure analysis of bacterial dipeptidyl aminopeptidase IV2016
- Author(s)
  ◯Roppongi, S., Tateoka, C., Suzuki, Y., Fujimoto, M., Morisawa, S., Iizuka, I., Kushibiki, C., Yonezawa, N., Ogasawara, W., Tanaka, N., Sakamoto, Y. and Nonaka, T.
- Organizer
  14th Conference of the Asian Crystallographic Association
- Place of Presentation
  Hanoi
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Structure-Function Relationships of S46 peptidases from Non-Fermenting Gram-Negative Rods2016
- Author(s)
  Roppongi, S., Suzuki, I., Iizuka, I., Inaka, K., Tanaka, H., Yamada, M., Ohata, K., Nonaka, T., Ogasawara, W., Tanaka, N. and　 Sakamoto, Y.
- Organizer
  American Society for Microbiology
- Place of Presentation
  Boston
- Year and Date
  2016-06-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Crystal Structure of Dipeptidyl Amino Peptidase 11 (DPP11) from Periodontal Pathogen.2016
- Author(s)
  SAKAMOTO Yasumitsu
- Organizer
  ISS R&D Conference
- Place of Presentation
  San Diego
- Year and Date
  2016-07-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Crystal structure of dipeptidyl amino peptidase 11 from Porphyromonas gingivalis2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.
- Organizer
  42nd Naito Conference on "In the Vanguard of Structural Biology
- Place of Presentation
  Sapporo
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] S46ペプチダーゼの構造機能相関の解明2016
- Author(s)
  ○伊藤康広、鈴木義之、阪本泰光、田中信忠、小笠原渉
- Organizer
  第16回日本蛋白質科学会
- Place of Presentation
  福岡
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 糖非発酵グラム陰性細菌由来ペプチド分解酵素の結晶化と構造解析2016
- Author(s)
  阪本泰光
- Organizer
  東北大学金属材料研究所金属材料研究所ワークショップ
- Place of Presentation
  仙台
- Year and Date
  2016-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 歯周病原菌Porphyromonas gingivalis由来dipeptidyl peptidase 11の精製と機能解析2016
- Author(s)
  中村彰宏、伊藤康広、鈴木義之、志田洋介、阪本泰光、田中信忠、小笠原渉
- Organizer
  第16回日本蛋白質科学会
- Place of Presentation
  福岡
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] 多剤耐性菌由来DPP-7を標的とする阻害剤の設計と評価　－宇宙ステーションで抗菌薬を開発する2016
- Author(s)
  ◯櫻井有紀、日高興士、宮崎杏奈、北條恵子、六本木沙織、阪本泰光、伊藤康広、鈴木義之、小笠原渉、田中信忠、津田裕子
- Organizer
  第66回日本薬学会近畿支部大会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Structural Analysis of Dipeptidyl Peptidase 11 (DPP11) from Porphyromonas gingivalis2016
- Author(s)
  ◯Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.:
- Organizer
  14th Conference of the Asian Crystallographic Association
- Place of Presentation
  Hanoi
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Structure analysis of dipeptidyl peptidase 11 from Porphyromonas gingivalis.2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N
- Organizer
  16th International Conference on the Crystallization of Biological Macromolecules
- Place of Presentation
  Prague
- Year and Date
  2016-07-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Enzymatic characterization of S46 peptidase from pathogenic bacteria2016
- Author(s)
  ◯Ito, Y., Nakamura, A., Roppongi, S., Sakurai, Y., Suzuki, Y., Hidaka, K., Tsuda, Y., Sakamoto, Y., Tanaka, N. and Ogasawara, W.
- Organizer
  The 5th International GIGAKU Conference in Nagaoka (IGCN2016)
- Place of Presentation
  Nagaoka
- Year and Date
  2016-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Structure and Functions of Dipeptidyl peptidase 11 (DPP11) from Porphyromonas gingivalis.2016
- Author(s)
  SAKAMOTO Yasumitsu
- Organizer
  The 2nd International Symposium Space Science of High Quality Protein Crystallization Technology
- Place of Presentation
  Tokyo
- Year and Date
  2016-10-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Crystal Structure of Bacterial Dipeptidyl Aminopeptidase IV Complexed with Peptide2016
- Author(s)
  Kushibiki, C., ◯Yonezawa, N., Roppongi, S., Tateoka, C., Suzuki, Y., Fujimoto, M., Morisawa, S., Iizuka, I., Ogasawara, W., Tanaka, N., Sakamoto, Y. and Nonaka, T.
- Organizer
  14th Conference of the Asian Crystallographic Association
- Place of Presentation
  Hanoi
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08322
[Presentation] Pseudoxanthomonas mexicana WO24由来ジペプチジルアミノペプチダーゼの構造解析2015
- Author(s)
  阪本泰光、鈴木義之、飯塚一平、館岡千佳、六本木沙織、藤本真友、伊中浩治、田中広明、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠
- Organizer
  第135回日本薬学会年会
- Place of Presentation
  デザインクリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Pseudoxanthomonas mexicana WO24 由来DAP BII の構造機能相関2015
- Author(s)
  阪本泰光、鈴木義之、飯塚一平、館岡千佳、六本木沙織、藤本真友、伊中浩治、田中広明、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠
- Organizer
  第3回物構研サイエンスフェスタ
- Place of Presentation
  エポカルつくば（つくば）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] First structure of Family S46 peptidase reveal exo-peptidase activity in Clan PA peptidases2015
- Author(s)
  飯塚一平、阪本泰光、鈴木義之、舘岡千佳、六本木沙織、藤本真友、伊中浩治、田仲広明、正木美佳、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠
- Organizer
  9th General Meeting of The International Proteolysis Society
- Place of Presentation
  ペナン、マレーシア
- Year and Date
  2015-10-05
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Structural and mutational studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis2015
- Author(s)
  阪本泰光、鈴木義之、飯塚一平、舘岡千佳、六本木沙織、藤本真友、伊中浩治、田仲広明、太田和敬、山田貢、合田浩明、野中孝昌、小笠原渉、田中信忠
- Organizer
  9th General Meeting of The International Proteolysis Society
- Place of Presentation
  ペナン、マレーシア
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Clan PA に属するExopeptidase family S46 の構造機能相関の解明2015
- Author(s)
  鈴木義之、阪本泰光、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2015年度年会
- Place of Presentation
  岡山大学津島キャンパス（岡山）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Clan PA S46ファミリーに属するDAP BIIの結晶構造解析2015
- Author(s)
  飯塚一平、鈴木義之、館岡千佳、六本木沙織、藤本真友、伊中浩治、田仲広明、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠、阪本泰光
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  矢巾町
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal Structure analyses of dipeptidyl aminopeptidase BII from P. mexicana WO24.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Organizer
  The 23rd Congress and General Assembly of the International Union of Crystallography.
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2014-08-11
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Pseudoxanthomonas mexicana WO24 由来 dipeptidyl aminopeptidase 複合体の結晶構造2014
- Author(s)
  六本木沙織、館岡千佳、森澤さおり、飯塚一平、藤本真友、鈴木義之、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  横浜産貿易ホール（横浜）
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Structural basis of exopeptidase activity of a dipeptidyl aminopeptidase BII, a member of the family S46 peptidases.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Organizer
  15th International Conference on the Crystallization of Biological Macromolecules.
- Place of Presentation
  ハンブルグ（ドイツ）
- Year and Date
  2014-09-17
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] 微小重力環境を利用したジペプチジルアミノペプチダーゼ結晶化2014
- Author(s)
  阪本泰光
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜（横浜）
- Year and Date
  2014-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal structure studies of dipeptidyl aminopeptidase BII from Pseudoxanthomonas mexicana WO24.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Organizer
  The 28th Symposium of the Protein Society
- Place of Presentation
  サンディエゴ（米国）
- Year and Date
  2014-07-27
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal Structures of Dipeptidyl aminopeptidases from Pseudoxanthomonas mexicana WO24.2014
- Author(s)
  Roppongi S, Suzuki Y, Iizuka I, Tateoka C, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N, Sakamoto Y, Nonaka T.
- Organizer
  New York Structural Biology Discussion Group Summer Meeting.
- Place of Presentation
  ニューヨーク（米国）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal structure analysis of dipeptidyl amino peptidase from P. mexicana WO24.2014
- Author(s)
  Roppongi　S, Tateoka C, Suzuki Y, Fujimoto M, Morisawa S, Iizuka I, Ogasawara W, Tanaka N, Sakamoto Y, Nonaka T.
- Organizer
  The 23rd Congress and General Assembly of the International Union of Crystallography.
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] ヒト由来環状化ヌクレオチドホスホジエステラーゼの立体構造2009
- Author(s)
  田中信忠、阪本泰光, 他
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば国際会議場
- Year and Date
  2009-03-25
- Data Source
  KAKENHI-PROJECT-18770096
[Presentation] ヒト由来環状化ヌクレオチドホスホジエステラーゼの立体構造2009
- Author(s)
  阪本泰光、田中信忠、一宮智美、野中孝昌、栗原正、中村和郎
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-18770096
[Presentation] Structural Comparison Studies For 2H Phosphoesterase Superfamily Proteins2007
- Author(s)
  Sakamoto Y, Tanaka N, Ichimiya T, Kurihara T, Nakamura T.K
- Organizer
  The 8th Conference of the Asian Crystallographic Association
- Place of Presentation
  Taipei
- Data Source
  KAKENHI-PROJECT-18770096
[Presentation] 医薬応用を目指した構造解析と構造機能解析支援のためのバイオインフォマティクス2007
- Author(s)
  田中信忠、日下部吉男、阪本泰光、由良敬
- Organizer
  タンパク3000総合シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18770096
[Presentation] STRUCTURAL COMPARISON STUDY for 2H phosphoesterase superfamily PROTEINS2007
- Author(s)
  阪本泰光
- Organizer
  The 8th Conference of the Asian Crystallographic Association
- Place of Presentation
  Howard International House(Taipei)
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18770096
[Presentation] Structural Comparison Analysis of 2H phosphodiesterase family proteins2007
- Author(s)
  Sakamoto Y, Tanaka N, Ichimiya T, Kurihara T, Nakamura T.K
- Organizer
  5th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18770096
[Presentation] Structural comparison analysis of 2H phosphodiesterase family proteins.2007
- Author(s)
  阪本泰光
- Organizer
  SNAC2007 5th International symposium on Nucleic Acids Chemistry
- Place of Presentation
  東京大学
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18770096

1. TANAKA Nobutada (00286866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. 日高興士 (30445960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 野中由香莉 (40710520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OGASAWARA Wataru (40292172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
5. Yoshida Akihiro (20364151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉成伸夫 (20231699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三好智博 (60534550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宇田川信之 (70245801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋晋平 (20805014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 多部田康一 (20401763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Roppongi Saori

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results

Sakamoto Yasumitsu 阪本 泰光

SAKAMOTO YASUMITSU 阪本 泰光

SAKAMOTO Yasumitsu 阪本 泰光

Research Projects

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糖非発酵グラム陰性細菌のペプチド代謝機構を標的とした抗菌薬開発Principal Investigator

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選択的ジペプチジルペプチダーゼ阻害剤による糖尿病関連歯周炎に対する創薬研究

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Drug discovery research targeting the mechanism of peptide metabolism in sugar non-fermenting Gram-negative bacteriaPrincipal Investigator

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Elucidation of the molecular basis of leukotoxin-receptor interactions and development of a novel periodontitis vaccine.

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Molecular basis for drug discovery of dipeptidyl amino peptidases from Non-Fermented Gram-Negative RodsPrincipal Investigator

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Structural and functional studies of dipeptidyl aminopeptidases from periodontal pathogen.Principal Investigator

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Crystal structure of 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, CNPase from human brainPrincipal Investigator

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[Book] 看護学学習辞典2008

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[Book] 看護学学習辞典2008

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[Journal Article] The Crystal Structure of Peptidase Toward Drug Discovery2019

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[Journal Article] Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues2018

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[Journal Article] Periplasmic form of dipeptidyl aminopeptidase IV from Pseudoxanthomonas mexicana WO24: purification, kinetic characterization, crystallization and X‐ray crystallographic analysis2017

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DOI

Data Source

[Journal Article] Structural and Functional Studies of Dipeptidyl Aminopeptidase from Non-Fermenting Gram-Negative Rods2016

Author(s)

Journal Title

Sakamoto Yasumitsu 阪本泰光

SAKAMOTO YASUMITSU 阪本泰光

SAKAMOTO Yasumitsu 阪本泰光

[Presentation] クスリ創りの新時代へ　～宇宙実験・アカデミア創薬・ロボット創薬のコラボレーションによる新薬創製への挑戦～2019